This article does a research into a theme that has not been studied specifically. This is curious, as the idea of philosophy is the most important one in Ortega y Gasset’s system. Here, it is considered concerning its specifity: the principles of pantonomy and autonomy his platitudinous nature and its integrating and critical functions. As it can be seen, Philosophy’s traditional characteristics. Ortega sets them out in a masterly way, reaching its hight literary brilliance when he praises Philosophy.

Recently published work showed that members of the PAQR protein family are activated by cell membrane rigidity and contribute to our ability to eat a wide variety of diets. Cell membranes are primarily composed of phospholipids containing dietarily obtained fatty acids, which poses a challenge to membrane properties because diets can vary greatly in their fatty acid composition and could impart opposite properties to the cellular membranes. In particular, saturated fatty acids (SFAs) can pack tightly and form rigid membranes (like (...) butter at room temperature) while unsaturated fatty acids (UFAs) form more fluid membranes (like vegetable oils). Proteins of the PAQR protein family, characterized by the presence of seven transmembrane domains and a cytosolic N‐terminus, contribute to membrane homeostasis in bacteria, yeasts, and animals. These proteins respond to membrane rigidity by stimulating fatty acid desaturation and incorporation of UFAs into phospholipids and explain the ability of animals to thrive on diets with widely varied fat composition. Also see the video abstract here: https://youtu.be/6ckcvaDdbQg. (shrink)

In this article, we offer a detailed study of two important episodes in the early history of high-energy physics, namely the development of the Chew and the Nambu-Jona-Lasinio models. Our study reveals that both models resulted from the combination of an old Hamiltonian, which had been introduced by earlier researchers, and two new approximation methods developed by Chew and by Nambu and Jona-Lasinio. These new approximation methods, furthermore, were the key component behind the models’ success. We take this historical investigation (...) to support two philosophical theses about the manner in which scientific modelling operates in high-energy physics. Both of these theses run counter to a view that is commonly accepted among philosophers of science: the view that all approximations can be embedded within an equivalent idealized system, and that whatever role the former might play in scientific modelling is therefore parasitic on the much more substantial work performed by the latter. Our first thesis, which we call “Distinctness,” states that approximation methods constitute an independent category of theoretical output from idealized systems. We thus believe that approximations and idealized systems constitute two independent types of objects, both of which are essential to the practice of modelling. Our second, more radical thesis is called “Content Determination.” Our claim here is that approximation methods can in fact be essential to assigning determinate physical content to the idealized systems with which they jointly operate. As we show, this is due to the fact that quantum field theory allows for a very thin characterization of idealized systems only, making the use of approximations necessary to supply additional content. We conclude the paper with a few reflections about the manner in which our two theses can be used to articulate David Kaiser’s views on the “vanishing of scientific theory” in physics after WWII. (shrink)

In this short contribution we explore the historical roots of recent synthetic approaches in biology and try to assess their real potential, as well as identify future hurdles or the reasons behind some of the main difficulties they currently face. We suggest that part of these difficulties might not be just the result of our present lack of adequate technical skills or understanding, but could spring directly from the nature of the biological phenomenon itself. In particular, if life is conceived (...) as autonomy in open-ended evolution, which would help to explain the highly complex and dynamic organization of the simplest known organisms (i.e., genetically-instructed cellular metabolisms), external synthetic implementations of such systems, or interventions on them, are bound to interfere with some of their characteristic transformation processes, both at the ontogenetic and phylogenetic scales. In any case, this will prove very revealing and productive, technologically and scientifically speaking, since the knowledge gathered from those implementations/interventions will be extremely valuable in establishing our capacities and limitations to fully comprehend, utilize, and expand the living domain as we know it today. (shrink)

The arrival of Buddhism to Uruguay is related to various historical and cultural factors, such as the democratic opening at eighties, the progressive globalization in the country, the break of post (modernism) with a hegemonic rationalist-positivist model, the emergence of so-called New Religious Movements and opening of goods symbolic-religious markets, generally aimed at middle and upper social strata with economic and cultural capital is conducive to the proposed use of existential and introspective way of life. In this paper we analyze (...) the arrival of the different Buddhist lineages in Uruguay (Tibetan and Japanese), and the historical and socio-cultural context which activates their emergency. (shrink)

Two experiments were conducted to examine whether the resistance to extinction obtained in evaluative conditioning (EC) studies implies that EC is a qualitatively distinct form of classical conditioning (Baeyens, Eelen, & Crombez, 1995 Baeyens, F, Eelen, P, and Crombez, G, (1995a). Pavlovian associations are forever: On classical conditioning and extinction, Journal of Psychophysiology 9 ((1995a)), pp. 127–141.[Web of Science ®], [Google Scholar]a) or whether it is the result of an nonassociative artefact (Field & Davey, 1997 Field, AP, and Davey, GCL, (...) (1997). Conceptual conditioning: Evidence for an artifactual account of evaluative learning, Learning and Motivation 25 ((1997)), pp. 446–464.[Crossref], [Web of Science ®], [Google Scholar], 1998 Field, AP, and Davey, GCL, (1998). Evaluative conditioning: Arti‐fact or ‐fiction?‐ A reply to Baeyens, De Houwer, Vansteenwegen, and Eelen (1998), Learning and Motivation 29 ((1998)), pp. 475–491.[Crossref], [Web of Science ®], [Google Scholar], 1999 Field, AP, and Davey, GCL, (1999). Reevaluating evaluative conditioning: A nonassociative explanation of conditioning effects in the visual evaluative conditioning paradigm, Journal of Experimental Psychology: Animal Behavior Processes 25 ((1999)), pp. 211–224.[Crossref], [PubMed], [Web of Science ®], [Google Scholar]). Both experiments included between‐subjects control groups in addition to standard within‐subjects control conditions. In Experiment 1, only verbal ratings were measured in order to evaluate the effect of postacquisition CS‐only exposures on EC whereas in Experiment 2, verbal ratings and postextinction priming effects were measured. The results showed that the EC effects are demonstrable in a between‐subjects design and that the extinction procedure did not have any influence on the acquired evaluative value of CSs regardless of whether the verbal ratings or the priming effects were used as dependent variables. The present results provide evidence that EC is resistant to extinction and suggest an interpretation of EC as a qualitatively distinct form of associative learning. (shrink)

The establishment of Mexico's National Bioethics Commission (Comisión Nacional de Bioética), in 1992, was conceived within the context of a global movement aimed at raising awareness of the ethical implications of technological and scientific development, especially in biomedicine. In 2005, a new decree put the commission under the scope of the Secretariat of Health and granted it technical and operational autonomy, allowing it to become a regulatory agency aimed at promoting a culture of bioethics, encouraging reflection on human health, and (...) developing guidelines for health care, research, and education, through a global, secular, and democratic perspective. The commission became the leading actor in the strategy for institutionalizing bioethics in Mexico after reforms to the country's General Health Act in 2011, which required that public, social assistance, or private health care facilities establish a hospital bioethics committee to address bioethical dilemmas or issues and, when relevant, a research ethics committee to address research with human subjects. This assignment has shifted the focus of the activities and goals of the National Bioethics Commission toward establishing these committees in line with current regulations and developing mechanisms to ensure that they operate with the highest standards of ethical conduct, performance, and accountability. (shrink)

The accuracy of proxies when they interpret advance directives or apply substituted decision-making criteria has been called into question. It therefore became important to know if the Andalusian Advance Directive Form (AADF) can help to increase the accuracy of proxies' predictions. The aim of this research was to compare the effect of the AADF on the accuracy of proxies' predictions about patients' preferences with that gained from informative and deliberative sessions about end-of-life decision making. A total of 171 pairs of (...) patients and their proxies were randomized to three groups. The control group's answers to the Life Sustaining Preferences Questionnaire (LSPQ) were compared with their proxies' answers to the same questionnaire. In one intervention group, the patients had already completed the AADF and given it to their proxies, who used it to guide their own answers to the LSPQ. In the second intervention (discussion) group, both patients and proxies attended two educative sessions guided by trained nurses and later filled in the LSPQ. Comparisons of accuracy and other variables showed a strong association with the discussion group. The findings show that promoting communication between patients and their proxies improves the accuracy of proxies' predictions much more than isolated use of the AADF form. (shrink)

En este artículo analizamos la cuestión de la presencia del mundo en los escritos de juventud de Simone Weil, con el objetivo de aprehender su concepción del tiempo. En ese sentido, intentaremos elucidar las relaciones ontológica y epistemológica que ella establece entre el hombre y el mundo. Esta perspectiva nos permite explorar la primera filosofía de la percepción weiliana y trazar las implicaciones existenciales que se desprenden de la experiencia del presente. Igualmente, examinamos la dificultad de pensar la inmovilidad en (...) la realidad humana a partir de la tensión problemática que plantea S.Weil entre las nociones de continuidad y eternidad. Palabras clave: Simone Weil, presencia, mundo, continuidad, eternidad, tiempo. (shrink)

This two-wave study investigated the temporal interplay between motivation and the intensity and reported impact of athletes’ emotions in training settings. In total, 217 athletes completed self-report measures of motivational climate, motivation regulations, emotional states (i.e., pleasant states, anger, and anxiety) experienced before practice at two time points during a 3-month period. Latent change score modeling revealed significantly negative paths from task-involving climate at time 1 to the latent change in the intensity of dysfunctional anxiety and anger, and significantly positive (...) paths from ego-involving climate at time 1 to the latent change in dysfunctional anger (i.e., intensity and reported impact). The paths from controlled motivation at time 1 to the latent change in the intensity of dysfunctional anxiety and vice versa were significantly positive. The path from controlled motivation at time 1 to the latent change in the intensity of functional anger was significantly positive, but not vice versa. In addition, the paths from dysfunctional anger (i.e., intensity and reported impact) at time 1 to the latent change in motivation regulations were significant, but not vice versa. Overall, evidence provided suggested that the temporal interplay of motivation and emotions is contingent on the specific emotions. The findings highlight the role of coach-created motivational climate and the importance of identifying high levels of controlled motivation to help athletes better adapt to psychological stress. (shrink)

La visión tradicional del pensamiento crítico (PC) fundada en un enfoque racionalista ha sido puesta en duda a partir de fines del siglo pasado por la ‘segunda ola’ del PC, la cual, a pesar de no ser un movimiento del todo definido, ha incluido aspectos como la imaginación, la creatividad y el trabajo cooperativo en su comprensión y en su aplicación a la enseñanza. Paralelamente, perspectivas actuales en psicología moral como el modelo ‘intuicionista social’ propuesto por Jonathan Haidt, representan un (...) desafío al modelo racionalista de la moral que suponen gran parte de las éticas normativas canónicas. Siendo que tanto el PC como el fundamento moral representan factores fundamentales en la enseñanza de ética, se hace explicito que esta última precisa también ser revisada. Es por ello que el presente trabajo analiza una perspectiva del PC alternativa a la tradicional basada en el potencial aporte de la metacognición y del modelo intuicionista social, con el fin de abrir nuevas vías de investigación para la actualización del fundamento moral que se supone en la enseñanza de ética. Para ahondar en ello, se ejemplificará la relevancia y aplicabilidad de la metacognición en la enseñanza de ética con situaciones vinculadas a la actual pandemia por Covid-19. (shrink)

La presente investigación tuvo como objetivo realizar un análisis del procedimiento abreviado contemplado en el Código Orgánico Integral Penal (COIP), partiendo del criterio de que ciertos aspectos de este procedimiento vulneran derechos fundamentales del investigado. Se destaca particularmente el requisito para el procesado de admitir los hechos que se le imputan para acceder a este procedimiento, lo cual, según la opinión mayoritaria de doctrinarios, compromete el principio de no autoincriminación, la presunción de inocencia y el derecho a un juicio con (...) todas sus fases. El objetivo de esta investigación fue analizar el procedimiento abreviado establecido en el Código Orgánico Integral Penal (COIP), con el propósito de identificar posibles vulneraciones de derechos fundamentales del investigado. Se buscó específicamente evaluar cómo el requisito de admitir los hechos imputados para acceder a este procedimiento podría afectar principios como el de no autoincriminación y la presunción de inocencia. A través de un enfoque cualitativo y utilizando diferentes métodos de análisis, se procuró determinar si el procedimiento abreviado, tal como está configurado, garantiza un debido proceso conforme a los estándares de derechos humanos y constitucionales. La metodología aplicada se sustentó en un enfoque cualitativo, utilizando los métodos inductivo, analítico, sintético y exegético. Se llevó a cabo un análisis documental de la bibliografía relacionada con el tema investigado, así como de instrumentos internacionales de Derechos Humanos, la Constitución de la República de Ecuador, el COIP y jurisprudencia vinculada a la materia. Los resultados de la investigación determinaron que el procedimiento abreviado tal como se encuentra regulado en el COIP beneficia al Estado y al sistema de justicia al agilizar ciertos procesos legales. Sin embargo, se evidenció que este procedimiento puede vulnerar derechos esenciales del procesado, como el principio de no autoincriminación y la presunción de inocencia. Por lo tanto, se concluye que el procedimiento abreviado afecta el debido proceso al comprometer garantías fundamentales. La investigación señala que el procedimiento abreviado regulado en el COIP, si bien puede ser beneficioso para la eficiencia del sistema de justicia, también conlleva riesgos significativos de vulnerar derechos fundamentales del procesado. Por lo tanto, se destaca la necesidad de revisar y modificar este procedimiento para garantizar el respeto absoluto al debido proceso y a las garantías individuales del investigado. (shrink)

This paper explores the antecedents of intra-organizational social capital from a comprehensive perspective that integrates leadership as the main antecedent. To be precise, we propose that intra-organizational social capital is a direct consequence of an organizational ethical and community context to which leadership in the servant dimension plays a transcendental role. Indeed, since the seminal work of Greenleaf the servant leadership concept has been widespread among business academics and professionals for the value it brings to the organization not only in (...) ethical but also in excellence terms. Among the recent styles and theories on leadership up to date, servant leadership fits perfectly an organizational ethical context both at the organizational or group level, acting in addition as a main promoter of that context. Furthermore, servant leadership is linked to the cultivation of helpful, altruistic and servant attitudes among the employees which are useful elements in the generation of social capital inside the organization. A model then for understanding the causes of intra-organizational social capital with a focus on servant leadership is here elaborated from which conclusions and implications for Management will be delineated. (shrink)

Background: Several authors have focused on the aesthetics of nursing care from diverse perspectives; however, there are few studies about the sublime and the beautiful in nursing. Aim: To identify beautiful and sublime moments in the context of the aesthetics of nursing care. Methods: A theoretical reflection has been contemplated about sublime and beautiful values in the context of the aesthetics of nursing care from the cultural history perspective. For that purpose, a revision of this issue has been completed. The (...) terms ‘beautiful’ and ‘sublime’ have been analysed to identify the characteristics of both in the context of nursing care. Ethical consideration: We have followed all ethical requirements regarding the sources, conducting research and authorship. There is no conflict of interest in this paper. Results: With aesthetic knowledge, the nurse expresses the artistic nature of nursing care by appreciating the act of caring for individuals. The sublime is a complex phenomenon, since apparently contrary feelings are interwoven. Nursing care is an art with an anthropological object-subject on which the ‘artist’ applies their prior knowledge and skills. Feelings and emotions that develop during the clinical nursing practice – especially at times sublime and beautiful, aesthetic – constitute experiences which are professionally significant. (shrink)

A evidência textual primária confirma que Schopenhauer estava ciente da adoção generalizada do confinamento solitário no sistema penitenciário americano e alguns de seus efeitos prejudiciais. Ele entende sua perniciosidade no que diz respeito ao tédio, fenômeno pelo qual é conhecido por ter nele pensado e analisado extensivamente. Neste artigo, eu interpreto o relato de Schopenhauer sobre o tédio e sua relação com o confinamento solitário. Defendo Schopenhauer contra a objeção de que os casos de confinamento servem apenas para ilustrar a (...) inadequação geral de sua explicação do tédio como a falta de coisas para se querer. Esta defesa chega à conclusão de que, ao contrário, alguém pode muito bem sofrer da falta de coisas para querer como resultado direto de estar confinado; e que o tédio, entendido como a privação de vontade — fenômeno que sugiro poder ser chamado de privação conativa — faz uma contribuição esclarecedora para a nossa compreensão teórica da nocividade do confinamento solitário. (shrink)

Introduction: The use of human samples in genomic research has increased ethical debate about informed consent (IC) requirements and the information that subjects should receive regarding the results of the research. However, there are no quantitative data regarding researchers’ attitudes about these issues. Methods: We present the results of a survey of 104 US and 100 Spanish researchers who had published genomic epidemiology studies in 61 journals during 2006. Results: Researchers preferred a broader IC than the IC they had actually (...) obtained in their published papers. US authors were more likely than their Spanish colleagues to support obtaining a broad IC, covering either any future research project or any projects related to a group of diseases (67.6% vs 43%; adjusted OR = 4.84, 95% CI, 2.32 to 10.12). A slight majority of researchers (55.8%) supported informing participants about individual genomic results only if the reliability and clinical validity of the information had been established. Men were more likely than women to believe that patients should be informed of research results even if these conditions were not met (adjusted OR = 2.89, 95% CI = 1.46 to 5.72). Conclusions: This study provides evidence of a wide range of views among scientists regarding some controversial ethical issues related to genomic research, suggesting the need for more study, debate and education. In the interim, journals might consider including the investigators’ policies regarding these ethical issues in the papers they publish in the field of genomic epidemiology. (shrink)

La crisis pandémica sufrida por el Covid-19 no tiene parangón, con un importante impacto económico y financiero, además de sanitario. Sin embargo, este propio marco nos permite y, a su vez, nos obliga a auditar los daños y repensar un nuevo marco jurídico y político que incluya a toda la ciudadanía mundial, sin penalización. La mirada para contabilizar el daño ciudadano no puede ignorar el enfoque de los derechos humanos desde la perspectiva feminista, sino que se requiere inexorablemente de una (...) obligatoria y urgente metodología de género. Sin perder de vista los objetivos de la Agenda Mundial de 2030, y el compromiso con la erradicación de la pobreza, la incorporación de esta metodología obliga a repensar la Sociedad del Trabajo y la Sociedad de cuidados para reivindicar la importancia que para el bienestar humano tiene el trabajo realizado dentro del hogar, y la urgencia de computarlo normativa y globalmente como generador de bienes y servicios. (shrink)

Causal cognition – how we perceive, represent and reason about causal events – are fundamental to the human mind, but it has rarely been approached in its cultural specificity. Here, we investigate this core concept among Wichi people, an indigenous group living in Chaco Forest. We focus on the Wichi, because their epistemological orientations and explanatory frameworks about ecosystem differ importantly from those documented among most Western majority-culture populations. We asked participants to reason about causes of events that involve the (...) hunhat lheley (inhabitants of the earth: humans, non-human animals, plants and spiritual beings) and other entities of their ecosystem (e.g., lagoon). We find a native ontological framework that encompasses three interacting organizing principles. This new evidence highlights ways in which native categories guide causal reasoning. Our research challenge long-held assumptions that dichotomies – nature-culture or natural-supernatural – are universal features of the human mind. (shrink)

The article provides arguments for including social-emotional education in moral education. The first part of the article presents an analysis of the concept of “emotional intelligence”, considering the history of its creation and the methodological difficulties with which this concept is burdened. In the second part of the article, the expectations that can be placed on emotional education classes are formulated. The starting point is empirical research that examined the effectiveness of past attempts to provide emotional education to adolescents and (...) adults. The last part of the article discusses the assumptions of the pedagogical movement that emerged in the 1990s, which calls for conducting classes in the field of so-called “character education”. Furthermore, experiences from social-emotional learning (SEL) classes developed by the University of Illinois are discussed. The text also briefly takes into account Spain's first experiences in the field of emotional education. (shrink)

L’enjeu de cet article est de défendre l’internalisme de Bernard Williams à propos de la raison pratique, en adoptant un point de vue différent de ce qui se fait habituellement dans la littérature. Les expériences de pensée impliquant des « excentriques idéalement cohérents » sont généralement présentées dans ce débat comme un argument majeur contre l’internalisme. Je conteste ce point et montre que nos intuitions concernant de telles figures impliquent en réalité une compréhension internaliste de la notion de raisons d’agir. (...) À cette fin, je suggère d’étendre la conception de Williams par une conception internaliste orientée sur le locuteur relativement à la signification des ascriptions de raisons externes. (shrink)

La obra de Thomas Piketty supone una contribución significativa para el pensamiento crítico. Sus tesis han renovado el alcance de la reflexión económica tradicional y canalizado su atención al estudio de la desigualdad, un asunto fundamental en el capitalismo contemporáneo cuya reflexión se impone, asimismo, a la filosofía social. En un intento por dar cuenta de la profundidad de su planteamiento, en las siguientes líneas abordamos las tesis principales de su aproximación, centrándonos particularmente en la dinámica r>g que presenta en (...) El Capital en el siglo XXI. A continuación, examinamos las soluciones principales que propone para una mejor distribución de la riqueza y el aumento de la justicia fiscal, así como ciertos aspectos problemáticos de su enfoque. Se concluye señalando posibles aportaciones del pensamiento pikettyano a la reflexión teórica en vinculación con las teorías de Streeck y Harvey. (shrink)

El objetivo de este artículo es definir qué son los estudios culturales, de género y literarios. Reflexionar acerca de la relación que hay entre ellos. Debatir cómo es posible el hecho de que puedan intersectarse éstos. E intentar explicar el funcionamiento teórico y metodológico de dichas interdisciplinas. Asimismo, este trabajo ofrece un panorama general con respecto a la situación actual de los estudios de género y los estudios literarios con esta perspectiva en México: ¿qué es lo que se está haciendo?, (...) ¿cómo?, ¿en dónde? (shrink)

En este este estudio presentamos una investigación sobre la genealogía de la razón de Estado y del golpe de Estado, según Michel Foucault. La genealogía de la razón gubernamental se desarrolló paralelamente a la comprensión científica del mundo, en los siglos XVI e XVII, como una realidad gobernada por leyes propias de la naturaleza. La genealogía de la razón de Estado incorporó los elementos “científicos” de la razón gubernamental como técnicas utilitarias para gobernar convenientemente un Estado, más allá del voluntarismo (...) del arbitrio del poder soberano. Foucault muestra en sus análisis genealógicos que el golpe de Estado fue concebido, ya en el siglo XVII, como una técnica gubernamental conveniente con la razón de Estado, cuyas tres principales características son: la necesidad, la violencia y la teatralidad. Palabras clave: Razón gubernamental. Razón de Estado. Golpe de Estado. Michel Foucault. (shrink)

Current Perspectives in Philosophy of Biology.

The aim of this paper is to render a detailed analysis of the correspondence with Clarke in order to shed some light in the relationship between the Principle of Identity of Indiscernibles and the Principle of Sufficient Reason. Most of the secondary literature takes for granted that Leibniz derives the Principle of Identity of Indiscernible from the Principle of Sufficient Reason in at least some parts of the correspondence. This would render the Principle of Identity of Indiscernibles a merely contingent (...) truth and not a necessary principle. I will argue that this interpretation is misleading, and that Leibniz never abandoned the idea that the Principle of Identity of Indiscernibles is a necessary truth. Although he is continuously using the Principle of Sufficient Reason in his argumentation, he keeps in parallel a strong argumentation that entails the necessity of the Principle of Identity of Indiscernibles. To achieve this goal, it will be necessary to point out first some contextual facts that may determine a correct understanding of the correspondence. It will be also necessary to frame the discussion about the principles into the broader debate on the possibility of Newtonian space. Finally, it will be shown that the mentioned hypothesis is supported by textual evidence throughout the entire correspondence. (shrink)