Introduction: Children affected by parental HIV are more likely than unaffected peers to experience trauma and are at-risk for negative psychological and social outcomes. This study aimed to examine the relationship between adverse childhood events and psychosocial functioning among children affected by parental HIV.Methods: A total of 790 children ages 6–17 from Henan, China were enrolled in a longitudinal, randomized controlled trial of a resilience-based psychosocial intervention. At baseline, children reported on numerous psychosocial factors, including trauma exposure, symptoms of anxiety (...) and depression, and peer social functioning. We used linear regression analysis to test the direct effect of trauma exposure on peer social functioning. We then tested whether depression and anxiety symptoms served as two potential parallel mediators in the association between trauma exposure and peer social functioning.Results: Trauma exposure was significantly associated with poor peer social functioning when controlling for key covariates. When depression and anxiety symptoms were added to the model, the association between trauma exposure and peer social functioning became nonsignificant. Instead, there were significant indirect effects from trauma exposure to peer social functioning via depression and anxiety.Conclusion: This study is among the first to link trauma exposure to peer social functioning deficits for children affected by parental HIV and demonstrates that symptoms of anxiety and depression mediate this relationship. Findings underscore the need for comprehensive psychosocial support for children affected by HIV, including screening for trauma exposure and mental health disorders. (shrink)

Ductin is the highest conserved membrane protein yet found in eukaryotes. It is multifunctional, being the subunit c or proteolipid component of the vacuolar H+‐ATPase and at the same time the protein component of a form of gap junction in metazoan animals. Analysis of its structure shows it to be a tandem repeat of two 8‐kDa domains derived from the subunit c of the F0 proton pore from the F1F0 ATPase. Each domain contains two transmembrane α‐helices, which together may form (...) a four‐helix bundle. In both the V‐ATPase and gap junction channel, ductin is probably arranged as a hexamer of subunits forming a central channel of gap junction‐like proportions. The two functions appear to be seggregated by ductin having two orientations in the bilayer. Ductin is also the major component of the mediatophore, a protein complex which may aid in the release of neurotransmitters across the pre‐synaptic membrane. It is also a target for a class of poorly understood viral polypeptides. These polypeptides are small and highly hydrophobic and some have oncogenic activity. Ductin thus appears to be at the crossroads of a number of biological processes. (shrink)

What role does audience uptake play in determining whether a speaker refuses or consents to sex? Proponents of constitution theories of uptake argue that which speech act someone performs is largely determined by their addressee’s uptake. However, this appears to entail a troubling result: a speaker might be made to perform a speech act of sexual consent against her will. In response, we develop a social constitution theory of uptake. We argue that addressee uptake can constitute a speaker’s utterance of (...) ‘no’ as a speech act of consent under some conditions, but that this does not prevent us from judging that an addressee committed rape. Second, we claim that addressee uptake is not the only form of uptake that matters—the uptake of other members of the discursive community matters too, and can override the addressee’s uptake, constituting the speaker’s utterance as the speech act it was intended to be. (shrink)

Recent perspectives on community investments suggest that they are opportunities for firms to create value for shareholders and other stakeholders. However, many corporate managers are still influenced by a widely held belief that such investments erode profits and are therefore unjustifiable from an agency perspective. In this paper, we refine and test theory regarding countervailing forces that influence community-based firm performance. We hypothesize that high levels of available slack will be associated with higher community-based performance, but that this relationship will (...) be moderated by three important governance variables: board independence, investment fund ownership, and CEO ownership. We find support for our hypotheses in longitudinal study of a large sample of U.S. corporations. (shrink)

Charles Erskine Stuart's studies of the MSS. of Seneca's tragedies are known to readers of the Class. Quart, from his two articles . Before he died he expressed a wish that his collations and notes should pass to me.

In 394 Agesilaus, treading in the footsteps of Xerxes, came from Asia by way of Thrace and Macedon into Thessaly, threw off the attacks of the Thessalian cavalry, proceeded without further trouble into Boeotia, and met the enemy at Coronea, where a great battle was fought. The question ought to have been asked before now, why was he not held up at Thermopylae?

The lover of Aeschylus and Verrall, remembering the appendix to Verrall's Seven against Thebes, pricks up his ears at etetumos and listens for a verbal equivocation.

Psychologists can learn from the procedural conventions of experimental economics. But the rationale for those conventions must be examined and understood lest they become constraints. Field referents and the choice of heuristic, matter for behavior. This theme unites the fields of experimental psychology and experimental economics by the simple fact that the object of study in both cases is the same.

Reading the Rhesus again the other day, I was struck by something strange in the rhythm of its trimeters. Whatever this was, it seemed to have nothing to do with metrical punctuation ; nor with the use of trisyllabic feet, though on that I shall have something to say. By listening hard I found a clue. The Rhesus is very spondaic at the beginning and the middle of the line.

In a recent article JRS, 68 f. Nicholas Horsfall sought to demonstrate that Corythus, which Virgil makes the original home of Dardanus, should be identified with Tarquinii, some 50 miles north-west of Rome, on the coast of Etruria, rather than with Cortona, roughly twice as far away, to the north, and inland. In doing so he expressed surprise that the Virgilian evidence should have been completely ignored by previous writers on the subject : and, using the Aeneid as the main (...) source on which his own argument was based, he supported his conclusion with a careful examination of several other aspects of the problem. (shrink)

In the middle of the third book of his Histories, Tacitus records some movements in the western provinces occasioned by the events of 69. The troops in Britain, he says, were partial to Vespasian, who had served there with distinction in the reign of Claudius, and a party was formed in his interest.

Poets should mean at least as much as they say. When Lucan wrote sola futuri Crassus erat belli medius mora. qualiter undas qui secat et geminum gracilis mare separat Isthmos,1 he ought to have been aware of the inept juxtaposition of slender and Thick. Did Sophocles mean all that he has implied ? I think so, because onoma, if it has not this implication, is strange, and a feeble excuse for it has to be sought two hundred and fifty lines (...) away. (shrink)

Does the desirability of social institutions for public goods provision depend on the extent to which they include mechanisms for endogenous enforcement of cooperative behavior? We consider alternative institutions that vary the use of direct punishments to promote social cooperation. In one institution, subjects participate in a public goods experiment in which an initial stage of voluntary contribution is followed by a second stage of voluntary, costly sanctioning. Another institution consists of the voluntary contribution stage only, with no subsequent opportunity (...) to sanction. In a third stage subjects vote for which institution they prefer for future interactions: do they prefer one that does allow sanctions or one that does not allow sanctions? Our results show that even though sanctions are frequently used when available, the clear majority of individuals vote for the institution that does not allow sanctions. Thus, a distinction is required between the principles that guide the choice of institutions and the principles that apply to actions guided by institutions. Our results indicate that it is the wealth generated by the institution that determines its desirability. (shrink)