BackgroundResponsive neurostimulation has been utilized as a treatment for intractable epilepsy. The RNS System delivers stimulation in response to detected abnormal activity, via leads covering the seizure foci, in response to detections of predefined epileptiform activity with the goal of decreasing seizure frequency and severity. While thalamic leads are often implanted in combination with cortical strip leads, implantation and stimulation with bilateral thalamic leads alone is less common, and the ability to detect electrographic seizures using RNS System thalamic leads is (...) uncertain.ObjectiveThe present study retrospectively evaluated fourteen patients with RNS System depth leads implanted in the thalamus, with or without concomitant implantation of cortical strip leads, to determine the ability to detect electrographic seizures in the thalamus. Detailed patient presentations and lead trajectories were reviewed alongside electroencephalographic analyses.ResultsAnterior nucleus thalamic leads, whether bilateral or unilateral and combined with a cortical strip lead, successfully detected and terminated epileptiform activity, as demonstrated by Cases 2 and 3. Similarly, bilateral centromedian thalamic leads or a combination of one centromedian thalamic alongside a cortical strip lead also demonstrated the ability to detect electrographic seizures as seen in Cases 6 and 9. Bilateral pulvinar leads likewise produced reliable seizure detection in Patient 14. Detections of electrographic seizures in thalamic nuclei did not appear to be affected by whether the patient was pediatric or adult at the time of RNS System implantation. Sole thalamic leads paralleled the combination of thalamic and cortical strip leads in terms of preventing the propagation of electrographic seizures.ConclusionThalamic nuclei present a promising target for detection and stimulation via the RNS System for seizures with multifocal or generalized onsets. These areas provide a modifiable, reversible therapeutic option for patients who are not candidates for surgical resection or ablation. (shrink)

本书配合《鬼谷子》的原文、译文及白话经典故事来诠释当今社会必学的谋略,使读者在短时间内获得丰富的历史知识和文学享受,领悟古典文化的精髓所在。.

Este artigo retoma os conceitos de poder disciplinar e biopoder em Michel Foucault para, então, fazer um diagnóstico do contexto pandêmico causado pela Covid-19. Ao se considerar que mais da metade da população mundial foi orientada ao isolamento social, bem como à alteração de hábitos cotidianos a fim de diminuir a propagação do vírus SARS-CoV-2, é possível perceber em Foucault as medidas da técnica disciplinar e da tecnologia biopolítica, ambas direcionadas à preservação da vida da população. Considera-se que o poder (...) disciplinar e o biopoder funcionam na atual pandemia num contexto inédito, marcado pelo avanço tecnológico. (shrink)

ABSTRACT The purpose of this paper is to reveal how the responses of the others compose and expand the narratives of an early years teacher and also how these responses appear in narratives in the context of non-face-to-face and asynchronous support, due to the covid-19 pandemic. The narrative methodology of research in education, in dialogue with the contributions of the Bakhtinian philosophy, was used to interpret the responses materialized in the narratives and the way the teacher reorganizes her work based (...) on them. It was shown that whereas the narratives were related to face-to-face work, the babies’ responses came up from the unfinishedness utterances that the teacher produced from her experience with them; as regarding the narratives about non-face-to-face work, the responses came from the utterances produced by the families, based on what they experienced in their relationship with the babies. In both situations, the teacher tried to reorganize her work in relation to the responses of her others. (shrink)

Este estudo propõe caracterizar Simá: romance histórico do Alto Amazonas, de Lourenço da Silva Araújo e Amazonas, como um “romance épico”, entendido como uma variante de romance histórico distinta da escola hegemônica representada por José Alencar. Esse romance, cujos modelos literários são a Ilíada e a Eneida, elege o rapto da mameluca Simá, chamada de “Helena do Rio Negro”, como a causa imediata da Rebelião de Lamalonga. O romance narra, no plano histórico, o massacre da nação indígena dos Manau pela (...) armada portuguesa e, no plano individual, o destino trágico da protagonista, apresentada como uma vítima inocente do conflito entre Portugal e Espanha. Publicado no mesmo ano de O Guarani, Simá oferece não uma narrativa mítica, como esse célebre romance, mas uma narrativa épica sobre a colonização europeia da Amazônia brasileira. (shrink)

Resenha: SIMAS, Luiz Antonio. _Umbandas: uma história do Brasil. _Rio de Janeiro: Civilização Brasileira, 2021.

Arap edebiyatı tarihinin dönemlerinden biri olarak Osmanlı dönemi Arap edebiyatı yaklaşık dört buçuk asırlık uzun bir dönemi kapsamaktadır. Modern dönemde Arap edebiyatı tarihi yazımına öncülük eden Carlo Alfonso Nallino (öl.1938), Hamilton Gibb (öl.1971), Régis Blachère (öl.1973) gibi müsteşrikler Osmanlı dönemi Arap edebiyatını yok saymış, dahası bir çöküş ve inkıta evresi olarak tanımlamışlardır. Bu makalede sözü edilen araştırmacıların dönemle ilgili iddialarının sağlamasını yapmak üzere Osmanlı’da Arap edebiyatı alanında var olan süreklilik, çeşitlilik ve gelişim durumu dönemin öncü iki edebiyatçısı ve eserlerinde ön (...) plana çıkan temalar üzerinden konu edilmiştir. Makale, literatür değerlendirmesinin de yapıldığı bir girişi, Osmanlı Dönemi Arap edebiyatı hakkında bir değerlendirmeyi, 17. yy. Osmanlı dönemi Arap edebi çevrelerinde meşhur olan edebiyatçılardan Yûsuf el-Bedî‘(öl. 1073/1662)’nin ve Şihâbuddîn el-Mûsevi Ebû Ma‘tûḳ (öl. 1087/1676)’un edebi şahsiyetlerini ve eserlerinde ön plana çıkan temaları, edebi süreklilik açısından incelemeyi içermektedir. Adı geçen iki edebi şahsiyetin seçilmesinin sebebi, edebiyatta hem geleneği korumuş olmaları hem de eserlerinin modern dönem edebiyatını etkilemiş olmasıdır. Genel olarak Osmanlı dönemi Arap edebiyatında ortaya konan edebî eserler hakkında, özel olarak makalenin konusunu teşkil eden edebiyatçılar hakkında henüz yeterli sayıda ilmî araştırmanın bulunmaması bir boşluk oluşturmaktadır. Makalemiz, önemini bu boşluğu bir nebze de olsa doldurma çabasından almaktadır. Makalemizde, bu dönemin edebî gelişim ve zenginlik açısından bir duraksamaya uğrayıp uğramadığı veya yok sayılacak denli edebî faaliyetlerden uzak olup olmadığı; edebiyat sahasında geleneğin sürekliliğinin sağlanıp sağlanmadığı ve edebî olgunluk ile gelişime ulaşılıp ulaşılmadığı sorularına cevap bulmak amaçlanmıştır. Dönemin iki usta edebiyatçısına ait edebî temaların süreklilik bakımından değerlendirilmesi suretiyle konuya objektif bir bakış açısı sunmak hedeflenmiştir. Makalede nitel araştırma yöntemlerinden betimleyici yöntem kullanılmış olup edebî metinlerden verilen örnekler sınırlı tutulmuştur. Osmanlı Döneminin, Arap edebiyatının sekteye uğradığı bir dönem olmayıp, kendisinden önceki edebî dönemlerin devamı olarak canlılığını sürdürdüğü ve modern döneme temel teşkil edecek çalışmaların yapıldığı verimli bir dönem olduğu sonucuna ulaşılmıştır. Yûsuf el-Bedî‘î’nin ve Ebû Ma‘tûḳ'un edebî zevkleri, tenkit yetenekleri ve şair kimlikleri, onları yetiştiren kültürel çevreyi yansıtırken, canlı bir entelektüel ortamın varlığını da gösterir. Şiirlerinde klasik kasidenin temalarını dönemlerine uygun şekilde işleyerek, Arap edebiyatının zengin mirasının nesilden nesile aktarıldığını kanıtlarlar. Onların edebî kişilikleri, yaşadıkları yüzyılın entelektüel düzeyini ve dönemin edebiyatçı profilini nitelikli bir şekilde temsil etmektedir. (shrink)

Islamic scholars, who encountered works on the classification of sciences together with their translation activities, formed their own classification traditions by classifying the sciences from different perspective. These classifications, which position the sciences by considering the connection between reason and revelation, and pointing to the hierarchy and relationship between the sciences, also reflect the understanding of science on which they are based. In this context, we can talk about two different classification traditions put forward by Islamic philosophers on the one (...) hand and Islamic scholars on the other. At this point, Tashkoprīzāda (d. 958/1561), one of the 16th century Ottoman scholars, created an original classification of sciences that influenced the future by benefiting from both traditions. Tashkoprīzāda, who sees the classification of sciences as a branch of science at the same time, has written four valuable books in this field, especially his book called Miftāhu’s-sa‘āda. These works contain rich information about the history of sciences as well as the classification of sciences. He determined the sciences of fiqh and usūl al-fiqh as a sub-branch of shar‘ī sciences and gave both historical and current information about these sciences by focusing on the works of influential scholars. Tashkoprīzāda, who is followed Hanafi sect and saw the Hanafi school as the most virtuous one, handled the fiqh section by putting the Hanafi school in the center. One of the remarkable points is that Tashkoprīzāda completed the part in which he dealt with the historical process of Hanafi fiqh with two great scholars, such as Mewlānā Calāleddīn al-Konewī (v. 672/1273) and Sheikh Badraddin as-Simāwī (v. 823/1420), who stood out with their Sufism. It is also important in terms of showing the mystic environment in which Tashkoprīzāda was influenced and his approach to the relationship between tasawwuf and fiqh. Another point that makes Tashkoprīzāda’s works stand out in terms of the history of sciences is that he mentions famous and acceptable works by referring to the curriculum of his period and surroundings. Thus, Tashkoprīzāda reveals the classification of sciences as a whole with its history, hierarchy and curriculum. (shrink)

Mehmet Akif İnan, Türkiye sendikacılığının önde gelen bir siması olarak bilinmesinin yanı sıra şâir ve yazarlığıyla da toplumun ekseriyeti tarafından tanınan bir şahsiyettir. Fakat sûfî kişiliği pek bilinmemektedir. Yapılan araş-tırmada İnan’a daha mücadeleci ve aktif karakter sağlayan hakikat, bilinmeyen tasavvuf ve tarîkat yönüdür. O, tasavvuf terbiyesinin kazandırdığı ahlâkla, insanlara önceden gösterdiği fedakârlığın daha fazlasını gösterir. İnan, tasavvuf ilmiyle benlik dönüşümünü gerçekleştirdikten sonra hem sendika çalışmalarında hem yazılarında ve şiirlerinde neslin kendi öz kültürü ve medeniyetiyle yetişmesi için gayret göstermiştir. İnan’ın tarîkata (...) intisabı yakın çevresi tarafından hayretle karşılanırken, tasavvufun kendisine kazandırdığı hal ile insanları kucaklaması, onların dertlerini paylaşması, arkadaşları tarafından "entelektüel derviş" olarak vasıflandırılır. Bu konuda yakın arkadaşları ve kendisini tanıyanlardan birçok eleştiri almıştır. Bu çalışmada, İnan’ın hayatı, eserleri, hayat mücadelesi ve pek bilinmeyen sûfî kişiliği ele alınmaktadır. (shrink)

Filosofias africanas é uma viagem ao pensamento africano pelos ganhadores do Prêmio Jabuti – Livro do ano. Num sentido amplo, o termo “filosofia” designa a busca do conhecimento iniciado quando os seres humanos começaram a tentar compreender o mundo por meio da razão. O termo pode também definir o conjunto de concepções, práticas ou teóricas, acerca da existência, dos seres, do ser humano e do papel de cada um no Universo. Na prática acadêmica, é usado para designar o “conjunto de (...) concepções metafísicas (gerais e abstratas) sobre o mundo”. A grande crítica que se faz às tentativas de caracterizar o pensamento tradicional africano como filosofia é a de que, na África, os nativos, defrontados com a grande incógnita que é o Universo, seriam incapazes de ir além do temor e da reverência, próprios das mentes ditas “primitivas”. A partir daí, o chamado “racismo científico”, um dos pilares do colonialismo no século XIX – desqualificando as fontes do saber africano conhecidas desde a Antiguidade –, negou a possibilidade de os africanos produzirem filosofia. Então, o reconhecimento como filósofos, no sentido estrito do termo, de pensadores nascidos na África e de uma linha filosófica deles originada só ocorreu a partir do século XX. Filosofias africanas trata tanto dos saberes ancestrais africanos, sua essência preservada nos provérbios, na diversidade multicultural e nos ensinamentos passados durante gerações por meio da oralidade, quanto da contribuição de filósofos africanos e afrodescendentes contemporâneos na atualização desses saberes, muitos dos quais pautados no decolonialismo. Nei Lopes e Luiz Antonio Simas, de maneira didática, mais uma vez escreveram uma obra que evidencia a complexidade, sofisticação e profundidade do pensamento africano e das perspectivas de mundo que sua filosofia provoca. (shrink)

In the present study, ordinary kriging and support vector machine have been used to develop three dimensional site characterization model of an alluvial site based on standard penetration test results. The SVM is a novel type of learning machine based on statistical learning theory, uses regression technique by introducing ε-insensitive loss function has been adopted. The knowledge of the semivariogram of the SPT values is used in the ordinary kriging method to predict the N values at any point in the (...) subsurface of the site where field measurements are not available. The comparison between the SVM and ordinary kriging model demonstrates that the SVM model is superior to ordinary kriging model in predicting N values in the site. (shrink)

An important question in epistemology is whether the KK principle is true, i.e., whether an agent who knows that p is also thereby in a position to know that she knows that p. We explain how a “transparency” account of self-knowledge, which maintains that we learn about our attitudes towards a proposition by reflecting not on ourselves but rather on that very proposition, supports an affirmative answer. In particular, we show that such an account allows us to reconcile a version (...) of the KK principle with an “externalist” or “reliabilist” conception of knowledge commonly thought to make that principle particularly problematic. (shrink)

A book filled with inspirations, tools, and techniques, offers a practical guide to discovering the power of living fully and completely in the now and significantly reducing stress by embracing Buddhist wisdom.

In this essay, my aim is to explain Vātsyāyana’s solution to a problem that arises for his theory of liberation. For him and most Nyāya philosophers after him, liberation consists in the absolute cessation of pain. Since this requires freedom from embodied existence, it also results in the absolute cessation of pleasure. How, then, can agents like us be rationally motivated to seek liberation? Vātsyāyana’s solution depends on what I will call the Pain Principle, i.e., the principle that we should (...) treat all aspects of our embodied existence as pain. If we were to follow this advice, we would come to apply the label of pain to all aspects of our embodied existence, including pleasure. This would undermine our attachment to our own embodied existence. I show that this fits with Vātsyāyana’s general theory of motivation. According to this theory, by manipulating the labels using which we think about the world and ourselves, we can induce radical shifts in our patterns of motivation. (shrink)

This article offers the first edition and translation of two heretofore unpublished pharmacological treatises by Abū Bakr al-Rāzī, namely Fī ittikhādh māʾ al-jubn and Fī manāfiʿ māʾ al-jubn, which seem to have formed part of a lost volume on dairy products. As it demonstrates, al-Rāzī’s examination of whey is connected to his philosophical interest in the complex nature of simple substances such as milk. The article also highlights how these two treatises built on the Greek pharmacological tradition by incorporating ingredients (...) from Persia and India. (shrink)

This paper establishes a dialogue between the later works of Wittgenstein, those of Cavell and the novels of J. M. Coetzee concerning the problem of violence, authority and the authoritative voice. By drawing on J. M. Coetzee's Waiting for the Barbarians and Diary of a Bad Year, the paper discusses lessons and insights on the nature of violence and the ways in which it can be accepted as “normal.” The term “normalization” is used in order to show how violence and (...) cruelty can become a “form of life” that develops according to its own actors, cultural practices and legitimacies. (shrink)

It is widely supposed that evolutionary debunking arguments against morality constitute a type of epistemological objection to our moral beliefs. In particular, the debunking force of such arguments is not supposed to depend on the metaphysical claim that moral facts do not exist. In this paper I argue that this standard epistemological construal of EDAs is highly misleading, if not mistaken. Specifically, I argue that the most widely discussed EDAs all make key and controversial metaphysical claims about the nature of (...) morality or the possibility of moral truth that belie their apparently epistemological character. I show that the debunking force of these EDAs derives largely from metaphysical claims about morality and their implications for the possibility of moral reduction, rather than from epistemological worries associated with the existence of an causal/non-moral explanation of our moral judgments. The paper briefly concludes with a dilemma that I believe confronts all EDAs such as those discussed in this paper: either such arguments are unsound, or else they prove too much, debunking our knowledge of science and the external world, as well as morality. (shrink)

This paper is about a tension between two theses. The first is Value of Evidence: roughly, the thesis that it is always rational for an agent to gather and use cost‐free evidence for making decisions. The second is Rationality of Imprecision: the thesis that an agent can be rationally required to adopt doxastic states that are imprecise, i.e., not representable by a single credence function. While others have noticed this tension, I offer a new diagnosis of it. I show that (...) it arises when an agent with an imprecise doxastic state engages in an unreflective inquiry, an inquiry where they revise their beliefs using an updating rule that doesn't satisfy a weak reflection principle. In such an unreflective inquiry, certain synchronic norms of instrumental rationality can make it instrumentally irrational for an agent to gather and use cost‐free evidence. I then go on to propose a diachronic norm of instrumental rationality that preserves Value of Evidence in unreflective inquiries. This, I suggest, may help us reconcile this thesis with Rationality of Imprecision. (shrink)

The search for definitions is ubiquitous in Sanskrit philosophy. In many texts across traditions, we find philosophers presenting their theories by laying down definitions of key theoretical categories, by testing those definitions, and by refuting competing definitions of the same theoretical categories. Call this the method of definitions. The aim of this essay is to explore a challenge that arises for this method: the paradox of definitions. It arises from the claim that the method of definitions is either (i) redundant (...) because it does not provide us any knowledge that we did not already possess, or (ii) impossible to successfully pursue because it leads to an infinite regress. Neither of these alternatives should be acceptable to the defender of this method. To focus our discussion, I will show how this challenge arose for—and was arguably resolved by—early Nyāya-Vaiśeṣika thinkers active in the first millennium CE and at the very beginning of the second millennium. In response to the paradox of definitions, these Nyāya-Vaiśeṣika thinkers claimed that the purpose of a definition is to remove either metaphysical ignorance about the distinction between theoretically significant kinds or kind-membership, or metalinguistic ignorance about the meaning or the application-conditions of theoretically significant terms. I will show how this discussion helps us to ward off certain misconceptions about the method of definitions in Nyāya-Vaiśeṣika. (shrink)

We read with interest Dominic Wilkinson’s article “Frailty Triage: Is Rationing Intensive Medical Treatment on the Grounds of Frailty Ethical?” on the utility of the Clinical Frailty Score in...

Judith Butler's The Force of Nonviolence attempts a creative mapping of the forces of nonviolence. With leading thinkers of the world coming up with creative cartographies of violence, Butler's mapping of nonviolence doesn't stand as an exercise in altering or undermining such cartographies. While these thinkers work with what stands as a categorical understanding of violence while reconstructing it as a destructive force innate to every being in the world, Butler departs from reiterating such understandings. However, with her mapping, Butler (...) doesn't seek to problematize the orientation of such understandings either—an orientation that lies in explaining the incurable fascist leaning of humans. Rather, she releases... (shrink)

In this article, I cast doubt on an apparent truism, namely, that if evidence is available for gathering and use at a negligible cost, then it’s always instrumentally rational for us to gather that evidence and use it for making decisions. Call this ‘value of information’ (VOI). I show that VOI conflicts with two other plausible theses. The first is the view that an agent’s evidence can entail non-trivial propositions about the external world. The second is the view that epistemic (...) rationality requires us to update our credences by conditionalization. These two theses, given some plausible assumptions, make room for rationally biased inquiries where VOI fails. I go on to argue that this is bad news for defenders of VOI. (shrink)