Until the recent spread of public-private partnerships, pharmaceutical firms had avoided research and development into neglected tropical diseases (NTDs). Because these are diseases that affect the poorest populations in developing regions, research and development initiatives have for the most part depended on the resources and expertise drawn from academia, international organizations, and intermittent state interventions in disease-endemic countries. Over the last few decades, however, public-private product development partnerships (PDPs) have been introducing new collaborative agreements in which the existing resources and (...) expertise combine with the those traditionally withheld by the pharmaceutical industry and global health NGOs. This paper explores recent transformations in the representation of NTDs by examining the shifting logic and spaces of knowledge production which the advent of PDPs has enabled. An analysis of two case studies focused on Chagas disease-related initiatives addresses recurring preoccupations in Science, Technology and Society studies as well as in critical analyses of PDPs: that is, the back-and-forth movement of the disease from being an object of scientific inquiry to a public health concern, and the legitimacy risks and material asymmetries entailed in global health PDPs. Both cases show that it is major global health stakeholders and experts in non-endemic countries, rather than transnational pharmaceutical firms, that exert the greatest influence upon these changing representations: PDPs attempt to expand the preexisting biomedical focus on NTDs by means of incorporating “real world” drug development preoccupations (which I term epistemic shifts), but they also combine their stated global humanitarian aim with security concerns about the diseases spreading to non-endemic, industrialized countries (which I term geographical shifts). (shrink)

Islam and Its Past: Jahiliyya, Late Antiquity, and the Qurʾan. Edited by Carol Bakhos and Michael Cook. Oxford Studies in the Abrahamic Religions. Oxford: oxford University Press, 2017. Pp. ix + 267. $85, £65.

Let be an infinite computable structure, and let R be an additional computable relation on its domain A. The syntactic notion of formal hypersimplicity of R on , first introduced and studied by Hird, is analogous to the computability-theoretic notion of hypersimplicity of R on A, given the definability of certain effective sequences of relations on A. Assuming that R is formally hypersimple on , we give general sufficient conditions for the existence of a computable isomorphic copy of on whose (...) domain the image of R is hypersimple and of arbitrary nonzero computably enumerable Turing degree. (shrink)

Quelle est la place du scepticisme dans l'œuvre d'un philosophe des Lumières comme Denis Diderot? Cet ouvrage vise à mettre en évidence les caractéristiques de la réception des instances sceptiques dans les œuvres de Diderot. L'analyse prend en considération l'ensemble du corpus diderotien, y compris sa contribution à l'Encyclopédie. L'objectif est aussi de montrer que la méthode sceptique de Diderot, qui consiste en l'usage de certaines argumentations, mais aussi en un ensemble de choix stylistiques, permet de mieux interpréter certaines spécificités (...) de sa pensée philosophique et de son matérialisme. Une meilleure compréhension du rôle du scepticisme dans la pensée de Diderot vise à apporter une contribution aux études sur ce qu'on définit comme le scepticisme des Lumières, en montrant qu'il serait plus exact de parler de scepticismes au pluriel, en raison des différences qui subsistent parmi les philosophes. Pour cette raison, ce livre propose des confrontations entre Diderot et ses sources sceptiques, mais aussi avec d'autres philosophes de son époque comme Montesquieu, Voltaire, D'Alembert et Hume"--Page 4 of cover. (shrink)

The article examines the influence of social capital on the quality of life of the Russian population and its particular components. The authors point to the problem associated with the social capital of the individual and determine the levels, namely the micro-level, meso-level, and macro-level, which form the social capital. In the course of the analysis, the authors reveal the theoretical and methodological approaches of foreign and Russian scientists to the concept of social capital and its components. Based on empirical (...) data from sociological research conducted in 2019, the article analyzes the structure of values of the adult population of Russia, highlights the characteristics of social capital and the degree of their influence on the formation of the quality of life. In the course of the research, the authors focus on the micro-level of the formation and influence of social capital, highlighting such components as a social activity and material security of an individual. In the course of the study, it was found that the social capital of a person affects the quality of a person's life, to a certain extent, forming the circle of his/her interests and values, as well as providing real opportunities for the realization of the interests of the individual and meeting his/her needs. The obtained results of the analysis can be useful for further study of the quality of life. (shrink)

We examine whether a taxpayer’s decision to choose a taxpayer-favorable characterization of income is associated with contextual and individual dimensions of that decision. Using a 2 × 2 factorial experimental design, we manipulate the prevailing social norm on whether there is a general belief that a specific form of income should be characterized as a capital gain or as ordinary income, and the group affiliation on whether the individual is making a tax characterization decision as a sole proprietor or as (...) a member of a group practice. Moreover, we measure participants’ fairness perception of characterizing the income as capital gains versus ordinary. We study the decisions of 180 graduate business and accounting students from two US business schools to explore these dimensions using a tax-ambiguous income situation. Results indicate that both contextual and individual dimensions impact taxpayer decisions. Specifically, the social norm and fairness perception of characterizing income as capital gains affects the likelihood of choosing such a characterization. Being a sole proprietor or a member of a group practice does not have any significant main effect. However, relative to all other conditions, taxpayers are most likely to characterize income as capital gains when both the social norms are for capital gains characterization and when the taxpayer is a member of a group practice. Results remain largely robust to a variety of alternative explanations. We conclude the paper with a discussion of our findings and their implications for tax policy, enforcement, and research. (shrink)

We consider a recursive model and an additional recursive relation R on its domain, such that there are uncountably many different images of R under isomorphisms from to some recursive model isomorphic to . We study properties of the set of Turing degrees of all these isomorphic images of R on the domain of.

The epistolary exchanges of early modern natural history have long been of interest to historians of science, as they reflect the dynamic nature of the emergent discipline better than the printed volumes of natural history. Less attention, at least until recently, has been paid to the unfinished pieces, the cryptic marginalia, and the practical notes that more often than not accompanied letters. Lists of specimens sent or requested were among the new tools at the naturalist's disposal for dealing with a (...) scientific world increasingly populated by objects. This essay seeks to reconstruct the genealogy of specimen lists by focusing on little-known apothecaries in northern Italy: the individuals traditionally held to be social counterparts to these modest strings of words. It seems that the operations at the back of the shop and the literature generated by the centuries-old drug and spice trades may have been a more defining influence on early modern naturalists than the humanist practices of indexing and commonplacing that were concurrently embraced by Italian studiosi. (shrink)

The paper addresses the problem of imaginative resistance in science, that is, why and under what circumstances imagination sometimes resists certain scenarios. In the first part, the paper presents and discusses two accounts concerning the problem and relevant for the main thesis of this study. The first position is that of Gendler (Journal of Philosophy 97:55–81, 2000), (Gendler, in: Nichols (ed) The Architecture of the Imagination: New essays on pretence, possibility and fiction, Oxford University Press, New York, 2006a), (Gendler & (...) Liao, in: Gibson, Carroll (eds) The routledge companion to philosophy of literature, Routledge, New York, 2016), according to which imaginative resistance mainly concerns evaluative scenarios, presenting deviant moral attitudes. The second account examined is that of Kim et al. (in: Cova, Réhault (eds) Advances in experimental philosophy of aesthetics, Bloomsbury, London, 2018), who insisted on the link between imaginative resistance on the one hand and counterfactual and counterdescriptive scenarios on the other. In the light of both theories, this paper discusses the importance of addressing the problem of imaginative resistance in the scientific enterprise in the light of some mechanisms of embodied simulation, based on the activity of mirror neurons and investigated within the framework of the Embodied Simulation Theory. (shrink)

Computable model theory, also called effective or recursive model theory, studies algorithmic properties of mathematical structures, their relations, and isomorphisms. These properties can be described syntactically or semantically. One of the major tasks of computable model theory is to obtain, whenever possible, computability-theoretic versions of various classical model-theoretic notions and results. For example, in the 1950's, Fröhlich and Shepherdson realized that the concept of a computable function can make van der Waerden's intuitive notion of an explicit field precise. This led (...) to the notion of a computable structure. In 1960, Rabin proved that every computable field has a computable algebraic closure. However, not every classical result “effectivizes”. Unlike Vaught's theorem that no complete theory has exactly two nonisomorphic countable models, Millar's and Kudaibergenov's result establishes that there is a complete decidable theory that has exactly two nonisomorphic countable models with computable elementary diagrams. In the 1970's, Metakides and Nerode [58], [59] and Remmel [71], [72], [73] used more advanced methods of computability theory to investigate algorithmic properties of fields, vector spaces, and other mathematical structures. (shrink)

This is a comprehensive analysis of the idea of libertas and its conflicting uses in the political struggles of the late Roman Republic. By reconstructing Roman political thinking about liberty against the background of Classical and Hellenistic thought, it excavates two distinct intellectual traditions on the means allowing for the preservation and the loss of libertas. Considering the interplay of these traditions in the political debates of the first century BC, Dr Arena offers a significant reinterpretation of the political struggles (...) of the time as well as a radical reappraisal of the role played by the idea of liberty in the practice of politics. She argues that, as a result of its uses in rhetorical debates, libertas underwent a form of conceptual change at the end of the Republic and came to legitimise a new course of politics, which led progressively to the transformation of the whole political system. (shrink)

We construct a recursive model , a recursive subset R of its domain, and a Turing degree x 0 satisfying the following condition. The nonrecursive images of R under all isomorphisms from to other recursive models are of Turing degree x and cannot be recursively enumerable.

In the past few years, behavioural, neuroimaging and neurophysiological studies have been suggesting that Embodied Simulation represents a constitutive feature of language understanding. However, this claim is still controversial, as is the definition of Embodied Simulation. In this paper, I aim at providing a more suitable definition of Embodied Simulation. I will then apply this definition to the study of bodily metaphors. Embodied Simulation gets us attuned with our social world and it provides us with both a brain and bodily (...) disposition, which is the starting point of many cognitive processes. Exploitation of the mechanism of simulation is particularly evident in the linguistic phenomenon of metaphors. Bodily metaphors are often so successful because they exploit this mechanism of brain and bodily attunement, enacted by means of Embodied Simulation. The role of Embodied Simulation and its importance for metaphor comprehension can be explained in two points: (1) Embodied Simulation allows speakers to share a bodily attitude during communicative exchanges; (2) by means of Embodied Simulation speakers directly experience the source domain during metaphorical mapping. (shrink)

The purpose of this article is to identify how modern Russia can build good relationships between multiple Russian religions and the state. At present there are many obstacles standing in the way of achieving this goal. The article includes a great many statistics, and discusses political, social, and religious views of the issue.The working Russian Constitution provides major legal provisions for democratic relationships between religions and the state. The law “On Freedom of Conscience and Religious Associations” (1997) clarified constitutional provisions. (...) It should not forgotten that Russia is a secular state claiming to respect all religions. No doubt the supremacy of Orthodoxy in Russia after 1721 and the extreme atheism that arose in the Soviet Union after 1917 influenced people’s minds greatly. While the countries in Western Europe were moving from religiosity to secularism, Russia was developing the other way around. But while respecting all religions, Russia should not forget to be mindful of extremism. Religious associations themselves are likewise uneasy about the danger presented by certain mystic, neo-pagan, and destructive sects. The author argues that the best compromise between religions and the modern Russian state canonly be achieved on the basis of equality and freedom. (shrink)

In this contribution we focus on one phenomenon that has a special role in pragmatic theorizing, namely metaphor, and select two issues deriving from theoretical models and prone to be tested experimentally. The first issue concerns the comprehension procedure, that is whether access to metaphorical meaning goes through a mandatory literal stage and thus is indirect, as predicted by a Gricean inspired account, or rather is retrieved directly. The question will be discussed by referring to behavioral and neurophysiological studies, which (...) advanced our understanding of the time course of metaphorical interpretation but proved not fully suitable to answer the question. The second issue revolves around the cognitive architecture of the pragmatic system as it operates in the case of metaphor comprehension. We will illustrate the contribution that functional neuroimaging, coupled with clinical investigations can provide to fine-tune the architecture of the system responsible for metaphor processing. Some outstanding questions are highlighted in the final part, aiming at sketching our interpretation of the experimental pragmatic enterprise. (shrink)

With every new recursive relation R on a recursive model , we consider the images of R under all isomorphisms from to other recursive models. We call the set of Turing degrees of these images the degree spectrum of R on , and say that R is intrinsically r.e. if all the images are r.e. C. Ash and A. Nerode introduce an extra decidability condition on , expressed in terms of R. Assuming this decidability condition, they prove that R is (...) intrinsically r.e. if and only if a natural recursive-syntactic condition is satisfied. We show that, while a recursive non-intrinsically r.e. relation may have a two element degree spectrum, a non-intrinsically r.e. relation which satisfies the Ash–Nerode decidability condition has an infinite degree spectrum. We also study several related decidability conditions and their effects on the degree spectra, including some conditions which are sufficient to obtain every r.e. degree in a spectrum. (shrink)

The aim of this paper is to address the problem known as “the puzzle of imaginative” use, related to the ambiguities of an imagination that sometimes distances us from reality, but at other times, as for example in the use of scientific thought experiments, is used to understand some important aspects of the real world. The problem is closely related to that of imaginative constraints. It will be shown how, particularly in the scientific enterprise, the epistemic value of imagination depends (...) on the embodiment of imagination itself. The work of scientific imagination, understood as an ability, will be re-read through the most recent studies on Embodied Simulation. This will make it possible to grasp in the imaginative act the link between creativity and method that is essential in the scientific enterprise. (shrink)

In spatial sequence synaesthesia ordinal stimuli are perceived as arranged in peripersonal space. Using fMRI, we examined the neural bases of SSS and colour synaesthesia for spoken words in a late-blind synaesthete, JF. He reported days of the week and months of the year as both coloured and spatially ordered in peripersonal space; parts of the days and festivities of the year were spatially ordered but uncoloured. Words that denote time-units and triggered no concurrents were used in a control condition. (...) Both conditions inducing SSS activated the occipito-parietal, infero-frontal and insular cortex. The colour area hOC4v was engaged when the synaesthetic experience included colour. These results confirm the continued recruitment of visual colour cortex in this late-blind synaesthetes. Synaesthesia also involved activation in inferior frontal cortex, which may be related to spatial memory and detection, and in the insula, which might contribute to audiovisual integration related to the processing of inducers and concurrents. (shrink)

A substantial body of experimental evidence has demonstrated that labels have an impact on infant categorization processes. Yet little is known regarding the nature of the mechanisms by which this effect is achieved. We distinguish between two competing accounts: supervised name‐based categorization and unsupervised feature‐based categorization. We describe a neurocomputational model of infant visual categorization, based on self‐organizing maps, that implements the unsupervised feature‐based approach. The model successfully reproduces experiments demonstrating the impact of labeling on infant visual categorization reported in (...) Plunkett, Hu, and Cohen (2008). It mimics infant behavior in both the familiarization and testing phases of the procedure, using a training regime that involves only single presentations of each stimulus and using just 24 participant networks per experiment. The model predicts that the observed behavior in infants is due to a transient form of learning that might lead to the emergence of hierarchically organized categorical structure and that the impact of labels on categorization is influenced by the perceived similarity and the sequence in which the objects are presented. The results suggest that early in development, say before 12 months old, labels need not act as invitations to form categories nor highlight the commonalities between objects, but they may play a more mundane but nevertheless powerful role as additional features that are processed in the same fashion as other features that characterize objects and object categories. (shrink)

ABSTRACTProviding an introduction to this special issue on the ancient notions of liberty and its modern perspectives, this essay contains, first, some reflections about the relation between the fields of ancient history and contemporary political theory. Building on the comments of the final roundtable with Kinch Hoekstra and Quentin Skinner, it then makes an attempt at extrapolating some theoretical understandings of liberty from a wide range of geographical and historical contexts covered in the contributions. Moving away from a strictly classical (...) Graeco-Roman focus, these include investigations from the second millennium BCE polities in the Levant to the Byzantine empire in the fifth-century CE. (shrink)

Purpose This paper aims to shed light on the threats that young people living in refugee camps face in their use of Facebook. While social media enable a participatory process of communication (Russo et al., 2008), which is based on the agency of the communicator and defined by their own cultural and moral goals (Lee et al., 2023), these platforms can at times be inappropriately pursued if the communicator lacks relevant skills. The outcome of such a pursuit can also inadvertently (...) damage social cohesion in the camp and lead to conflict. Design/methodology/approach A total of 17 semi-structured interviews were carried out in 2023 with young people between the ages of 20 and 29 living in Kakuma refugee camp. The young refugees were asked questions related to their own behaviour and practices on Facebook and to those of their peers. The focus was specifically on the context of the interactions with other youth in Kakuma and on the camp’s Facebook groups or pages. Findings Findings reveal that limited knowledge, understanding and awareness of the functioning and affordances of social media platforms such as Facebook are leading young refugees towards multiple risks involved in public online interactions. This has significant negative impacts not only on the lives of the youth who are active on social media in the camp but also on the relationships with their peers and overall community harmony. Originality/value A number of studies have identified some of the dangers arising for refugees operating in online spaces, and particularly on social media platforms (see, for example, Tech Transparency Project, 2022; Dekker et al., 2018). Yet, there is a lack of research on the outcomes that young refugees face in their immediate virtual and physical environment as a result of their online behaviour. To the best of the author’s knowledge, this study is the first to bring to light the nature of the interactions and the dynamics that young, encamped refugees engage in on Facebook and to offer useful reflections that can inform digital literacy efforts carried out by development agencies. (shrink)

In his 2011 article “Global Bifurcation: The Decision Window” Ervin Laszlo notes that “we have reached a watershed in our social and cultural evolution. The sciences of systems tell us that when complex open systems … approach a condition of critical instability, they face a moment of truth: they either transform or break down.” In this article we provide our own vision of this Global Bifurcation. This work stems naturally from the research highlighted in the article titled “Transition to Crisis-Free (...) Development: A Myth or Reality?” that was published in World Futures in 2014. In our new article, we move forward suggesting that crises-free development is not only possible but is also very likely, and paradoxically the world is now going through the most challenging transition from one paradigm of development to another. Based on our previous research as well as the findings of the Fifth Report to the Club of Rome, we suggest reasons for the development and implementation of a megaproject featuring a new model of life so as to make the paradigm shift possible, exclude negative implications of the upcoming technological “singularity,” and foster the achievement of an objectively defined goal of development, and this should reasonably require support from and direct involvement of the United Nations. The mechanism for implementation of this model suggests coordinating interests of the government, society, and business communities on each level with interests of particular individuals. (shrink)

v. 1. Commentaria in Aristotelem Armeniaca-Davidis Opera.

Can we really transcend our own human point of view in approaching the non-human? Rather than confining anthropomorphism in the field of the superstitious or identifying it with anthropocentrism, we propose a “weak” anthropomorphism. By adopting phenomenology as methodology, particularly Merleau-Ponty’s notions of corporeity and flesh, we suggest that anthropomorphism is the result of a shared bodily perception: first of all, we are-in-the-world. What we have is not a divide between the human and the non-human, but rather a blurred and (...) fuzzy compound of human and non-human features, where the wild coincides with this symbiotic unit. (shrink)