Blood coagulation is regulated through a complex network of biochemical reactions of blood factors. The main acting enzyme is thrombin whose propagation in blood plasma leads to fibrin clot formation. Spontaneous clot formation is normally controlled through the action of different plasma inhibitors, in particular, through the thrombin binding by antithrombin. In the current study we develop a mathematical model of clot formation both in quiescent plasma and in blood flow and determine the analytical conditions on the antithrombin concentration corresponding (...) to different regimes of blood coagulation. (shrink)

Darwin described biological species as groups of morphologically similar individuals. These groups of individuals can split into several subgroups due to natural selection, resulting in the emergence of new species. Some species can stay stable without the appearance of a new species, some others can disappear or evolve. Some of these evolutionary patterns were described in our previous works independently of each other. In this work we have developed a single model which allows us to reproduce the principal patterns in (...) Darwin’s diagram. Some more complex evolutionary patterns are also observed. The relation between Darwin’s definition of species, stated above, and Mayr’s definition of species is also discussed. (shrink)

Betrifft die Handschrift Cod. 555 der Burgerbibliothek Bern.

The Ecclesiastical History of Orderic Vitalis has been called `the greatest of all medieval chronicles'. Written in Normandy between 1114 and 1141, it is a detailed history of the Norman people and their conquests, full of vivid, often penetrating portraits of the lives and characters of kings and queens, lords and bishops, simple knights, and humble villagers. The chronicle gives a unique, authentic picture of feudal society during a period of rapid change in church and state which saw the emergence (...) of the Anglo-Norman realm, the spread of new forms of monasticism, and the launching of the Crusades. Published in 1968, volume II of Marjorie Chibnall's six-volume edition of the Ecclesiastical History is now available for the first time in paperback. `a superbly edited Latin text and a unique English translation of the work of a major historian' American Historical Review `Mrs Chibnall is giving us... her edition of a classical medieval text which will itself become a classic of medieval scholarship.' Times Literary Supplement. (shrink)

This book is about the relationship between necessary reasoning and visual experience in Charles S. Peirce’s mathematical philosophy. It presents mathematics as a science that presupposes a special imaginative connection between our responsiveness to reasons and our most fundamental perceptual intuitions about space and time. Central to this view on the nature of mathematics is Peirce’s idea of diagrammatic reasoning. In practicing this kind of reasoning, one treats diagrams not simply as external auxiliary tools, but rather as immediate visualizations of (...) the very process of the reasoning itself. Thus conceived, one's capacity to diagram their thought reveals a set of characteristics common to ordinary language, visual perception, and necessary mathematical reasoning. The book offers an original synthetic approach that allows tracing the roots of Peirce’s conception of a diagram in certain patterns of interrelation between his semiotics, his pragmaticist philosophy, his logical and mathematical ideas, bits and pieces of his biography, his personal intellectual predispositions, and his scientific practice as an applied mathematician. (shrink)

Edited with a facing-page English translation from the Latin text by: Chibnall, Marjorie.

The paper focuses on the review of current literature on formal philosophy. Special attention is paid to the review of the book «Introduction to Formal Philosophy» [Hansson, Hendricks, 2018]. The book is a consistent introduction to the problems of formal philosophy, a research tradition that relies on the precise mathematical tools in order to study traditional philosophical problems. The methods of formal philosophy are successfully applied not only to the problems of ontology, epistemology and philosophy of language but also relevant (...) for the problems of ethics, axiology and social philosophy. The book demonstrates that it is not correct to identify formal philosophy with another area of study – philosophical logic, since formal philosophy uses not only logical methods of analysis, but also uses the tools of game theory, decision theory, probability theory, Bayesian statistics, and other theories. Although the book has a propaedeutic character, it also contains some open problems. These problems include the aggregation of the opinions of the group under the condition of a conflicting base of premises in the theory of public choice, there are still open problems in the interpretation of Arrow’s impossibility theorem and others. Certainly, formalization in itself is not a general solution to the particular philosophical problem, but only a tool that allows to formulate a problem in a more rigorous and precise way, which sometimes allows to reveal some unexpected consequences, some implicit contradictions and new solutions. Despite the importance of the concept of coherence in ethics, decision theory, philosophy of law, Bayesian epistemology, philosophy of science, the existing formalizations of the concept of coherence are highly specialized for epistemology, researchers recognize the lack of the relevant explanatory models. Overall, the book is an excellent introduction in to the field of formal philosophy, which provides a general overview of different aspects of formal philosophy and the opportunity to study particular research topics by means of an extensive bibliography accompanying each of the chapters. (shrink)

Hunting for sport or pleasure is ethical because (1) it does not violate any animal’s moral rights, (2) it has as its primary object the exercise of human skills, which is a sufficient good to compensate for the evil that results from it, namely, the death of the animal, and (3) it contributes to the ecological system by directly participating in the balancing process of life and death upon which the ecosystem thrives, thus indirectly benefiting the human community. As such, (...) hunting is not only a natural good, but also a moral good. (shrink)

The paper aims to disclosure of key points in the development of the German tradition of historiography of philosophy after the 90s of the 18th century. The starting point was the so-called «dispute about the method» of historiography, which erupted in the last decade of the 18th century not without the influence of Kant’s «critical philosophy». Its participants (Reinhold, Fülleborn, Goess, Grohmann, Tennemann, and others) put forward different theses, but they agreed that it is Kant’s philosophy that makes it possible (...) to create a «philosophical history of philosophy». A type of historiography was formed, which was based on the criterion of «progress of philosophy» and Kant’s position was considered as a standard for any historiography. Subsequently, other types of historiography were formed, which followed either the opposite criterion of «regress» or «decadence», or tried to combine both of these criteria (Hegel). In the second half of the 19th century «history of problems» becomes widespread as a principle of research and presentation of the history of philosophy, its main representatives were W. Windelband, N. Hartmann, H. Heimsoeth. Instead, in the second half of the 20th century the dominant type of historiography is the «history of concepts», which finds linguistic and philosophical justification in Gadamer’s philosophical hermeneutics. In recent decades, the German tradition of historiography has been enriched by K. Flasсh’s project «historical philosophy» and by D. Henrich program «constellation research». In both of these projects, there is a noticeable attraction to microhistory, going beyond the «classic» texts, discovering hitherto unknown figures and sources that significantly expand the established practice of the historiography of philosophy. (shrink)

This article is a response to A. Patkul’s review of my translation of D. Jacquette’s book “Alexius Meinong, the Shepherd of Non-Being.” I disagree with reviewer’s opinion on a number of issues. One of the objections is that A. Patkul proceeds from the implicit (and sometimes explicit) opposition of analytical and continental philosophy when considering the contents of a book written by an analytical philosopher, and moreover translated by an analytical philosopher. This attitude is manifested by him in two trends. (...) Firstly, it is an emphasis on the already well-known sides of the Meinong’s theory of objects, which is rather of historical and philosophical interest, tending more to repeat the “Brentanian” roots and phenomenological aspects of Mining. Actually, the application of Meinong’s ideas to modern philosophical problems, which is the subject of Jacquette’s book, is practically ignored. Secondly, reviewer’s claims to the terminological decisions of the translator turn out, in addition to trivial typos, to be the result of all his desire to keep Meinong in the bosom of often scholastic terminology, with the recommendation to make do with Latin tracing paper. From my point of view, despite the well-known quirkiness of the terminology of Meinong himself, when translating, one should strive to convey the meaning in terms understandable to the reader. (shrink)

The article analyzes the concept of «reception», which has recently gained popularity, but remains not sufficiently clarified in studies of the history of philosophy. It is assumed that the concept has become the subject of explicit methodological reflection only in the reception aesthetics (Rezeptionsästhetik) of the Constance School of Literary Studies, where it not only opposes the concept of influence, but is interpreted in the context of a horizontal structure for text understanding. At the same time, it is important to (...) distinguish not only the «historical horizon» and the «horizon of modernity» (Gadamer), but also the «horizon of expectations» in its duality: both coded in the text itself and the life practice of the reader, «inter literary» and «external literary» horizons of expectation. The empirical trend of the reception study, developed later, makes it possible to formulate a number of specific proposals for the methodology of historical and philosophical research, which focuses on the principle of «history of receptions». It is clear that only «reproductive» and «productive» reception categories are relevant to this type of research. In particular, it is an analysis of the institutional prerequisites for the reception, the classification of the source base of that received, the channels (re)broadcast of that received, the specification of the types of scientific communication, the tradition determined positive or negative factors of reception, the status of philosophy in particular historical periods. (shrink)

This essay is concerned with different approaches to the elucidation of action. It explicates the influence of Aristotle’s theory of action on the development of the modern philosophy of action, provided, first of all, by Reductionist and Causalist’s points of view. The author argues that the denial of the physical and psychological components of the action allows to conclude, firstly, that action is a social concept, logically dependent on the accepted rules of conduct; secondly, that it is fundamentally not descriptive, (...) but ascriptive in its character; and thirdly, that it is a defeasible concept to be defined through exceptions and not by a set of necessary and sufficient conditions whether physical or psychological. (shrink)

This chapter contains sections titled: Notes.

This paper deals with the so-called “external history” of the origin of Critique of the power of judgment that is based primarily on the philosopher’s correspondence in the period between May 1787 and October 1789. Two letters from Kant to Reinhold (28.12.1787 and 12.05.1789) as well as modifications in the interpretation of the term “aesthetics” in the first Critique (KrVA 22, B 35-36) are crucial for the evolution of the project Critique of Taste in the book Critique of the Power (...) of Judgment. Special attention was paid to the debate between some modern scholars and editors about the importance of the reports on ‘Grundlegung’ / ‘Grundlage’ of Critique of Taste in the initial phase of work on the text. However, the available evidence does not allow us to reconstruct the “internal history” of the development of Kant’s thought during the period of writing the third Critique. Some modern scholars try to establish other objective criteria for this kind of reconstruction by identification in the text of Critique direct or hidden hints or citations to the literature of the 18th century. The author considers that the use of so-called “reflections” from the philosopher’s manuscript heritage, which can be seen as the formation and development of certain concepts of Kant’s theory, can be fruitful. The well-known problem of dating the reflections can be partially solved if terminus a quo will be not the published works, but Kant’s lectures on anthropology and logic taught at that time. (shrink)

Notizie biografiche. -- Il "Principe." -- I "Discorsi sopra la prima deca di Tito Livio." -- Le "Istorie florentine.".

Review of Vassallo, C. (2021). The Presocratics at Herculaneum. A Study of Early Greek Philosophy in the Epicurean Tradition. Berlin: De Gruyter.

This essay is concerned with the applicability in modern conceptual jurisprudence of a particular methodology for defining concepts, namely, per genus proximum et differentiam specificam. We explicate the origin of this method and how it was applied by Aristotle, Porphyry, and Boethius, arguing that H. L. A. Hart’s views about the “open texture” of language, which is context-sensitive, call into question the applicability of this methodology in modern conceptual jurisprudence.

The review introduces the main topics of the reports of the seminar participants of the Kant Society in Ukraine, held at the National University “Kyiv-Mohyla Academy” in December 2019. The speakers focused on the interpretation of I. Kant’s note on the “great light” in various historical and systematic contexts: from the evolution of the doctrine of space through the problem of metaphysical cognition and the new theory of judgment down to the concepts of normativity and conceptuality of human cognition.

Kant first publicized the concept of “metaphysics of morals” in the Critique of Pure Reason and further justified it in other works. However, we can state some distinctive features and perspectives of this project. There are reasons to single out three meanings of this concept: the entire project of pure moral philosophy (MM1), the late work with the same name Metaphysics of Morals (1797) (MM2), the chapter in Groundwork (1785) on “Transition from popular moral philosophy to the metaphysics of morals” (...) (MM3). It is obvious that MM2 and MM3 belong to MM1 as a whole systematic project of the metaphysics of morals. Among Kant scholars was established the view that Kant’s project of “metaphysics of morals” was “completely new”, and the concept itself is Kant’s “creature” (G. Tonelli, R. Brandt). Instead, recent research shows that this project belongs to the modern tradition of universal ethics (Pufendorf, Wolff and his school). (shrink)

The progress in computer programming leads to the shift in traditional correlation between intuitive and formal components of mathematical knowledge. From epistemological point of view the role of intuition decreases in compare with formal representation of mathematical structures. The relevant explanation is to be found in D. Hilbert’s formalism and corresponding Kantian’s motives in it. The notion of sign belongs to both areas under consideration: on the one hand it is object of intuition in Kantian de re sense, on the (...) other hand, it is part of formal structure. Intuitive mathematical knowledge is expressed by primitive recursive reasoning. The W. Tait’s thesis, namely, that finitism as methodology of mathematics is equivalent to primitive recursive reasoning is discussed in connection with some explications of Kantian notion of intuition. The requirements of finitism are compared with normative role of logic. (shrink)

Given a quantum system with a very large number of degrees of freedom and a preferred tensor product factorization of the Hilbert space we describe how it can be approximated with a very low-dimensional field theory with geometric degrees of freedom. The geometric approximation procedure consists of three steps. The first step is to construct weighted graphs with vertices representing subsystems and edges representing mutual information between subsystems. The second step is to deform the adjacency matrices of the information graphs (...) to that of a low-dimensional lattice using the graph flow equations introduced in the paper. The third step is to define an emergent metric and to derive an effective description of the metric and possibly other degrees of freedom. To illustrate the procedure we analyze two information graph flows with geometric attractors and metric perturbations obeying a geometric flow equation. Our analysis also suggests a possible approach to quantum gravity in which the geometry emerges directly from a quantum state due to the flow of the information graphs. (shrink)

Jeremy Bentham is usually seen as an anti-realist political thinker, or a proponent of what Bernard Williams has termed ‘political moralism’. This article questions that prevalent view and suggests instead that there are good grounds for considering Bentham a political realist. Bentham’s political thought has considerable commonalities with that of the sociologist and political realist Max Weber: both agree that politics is a unique domain of human activity defined by its association with power; that consequently, ethical conduct is unavoidably inflected (...) by power in politics; that a commitment to truth in politics can only ever be contingent; and that politics has a set of basic conditions that it would be not only misguided but dangerous to attempt to transcend. Whilst it is often held that Bentham advanced a reductive framework for understanding politics, in fact, his utilitarianism was a far more realistic approach to political ends and means than has generally been acknowledged, and one that contemporary political theory realists would benefit from taking seriously. (shrink)

Jewish short stories are explained from the viewpoint of many-valued logic. On the basis of some examples, we show, how their contents may be logically interpreted.

This article argues that Jeremy Bentham put forward a distinctive and original theory of representative democracy which can be helpfully analysed through his concept of the ‘deputy’. A deputy, Bentham argued, evoked a specific political relationship between governors and the governed – a relationship that was functionally different to that between the people and a ‘representative’ or a ‘delegate’. Whereas a representative was suggestive of too great a degree of governmental independence from the people and a delegate implied an excessive (...) dependency of governors upon the governed, a deputy for Bentham best described the relationship between the rulers and the ruled that should subsist in a representative democracy. A political form based on deputies, who were to be relatively free to conduct the business of government yet simultaneously accountable to their sovereign electors, was the only way in his eyes to guarantee the promotion of utility in politics and the security of the people from being misruled. (shrink)

In spite of all the industrious efforts Peirce scholars have made so far, Peirce’s biography still retains a number of gaps, among which the problem of identity of Peirce’s second wife, Juliette Froissy, stands out most significantly. It is all the more important that, as some scholars suggest, the discovery of any reliable facts about Juliette could provide an explanation to some of the decisions Peirce had made, which irrevocably changed the course of his life, as well as his semiotic (...) theory. By courtesy of Professor Dr. Nathan Houser and the Peirce Edition Project, the writer of the present paper was granted access to the archive materials containing the Max H. Fisch — Maurice Auger correspondence and Victor Lenzen’s notes on Juliette. The paper aims at arranging the dispersed data obtained from these and other sources into a set of several distinct versions, which curiously refer to each other and collectively impose a certain order on some major abductions concerning Juliette’s identity. (shrink)

The relationship between logic and ethics is one of the basic and most essential questions of classical philosophical analysis. Since the time of the Pythagoreans, the fundamental unity of the two – whether by means of vague intuition, an elaborate conceptual scheme, or even a carefully crafted lifestyle – has led philosophers to identify truth and virtue. In his critical philosophy Kant put this unity of truth and virtue to extensive and rigorous trial to determine what conditions, if any, a...

The article is devoted to reviewing and analyzing the results of the All-Russian scientific and practical conference “Public administration in new realities: modern challenges and opportunities”, held in Chelyabinsk on October 26—27, 2022, and is a digest of the main events of the conference.

The article examines a number of issues related to the specifics of information dissemination under the conditions of communicative practice of both an individual level and the functioning of mass media. The main attention is paid to the issue of the deliberate spread of disinformation. In this context, the phenomenon of "hybrid war" and the place of the information component in it, the issue of using narratives as an effective means of mass information damage, and the specifics of the process (...) of "devaluation of the word". The need to develop mechanisms to counteract the phenomena of "abuse of freedom of speech" and "simulative democracy" to ensure the survival and sustainable development of democratic societies is substantiated. (shrink)