In light of the development of “CRISPR” technology, new promising advances in therapeutic and preventive approaches have become a reality. However, with it came many ethical challenges. The most recent worldwide condemnation of the first use of CRISPR to genetically modify a human embryo is the latest example of ethically questionable use of this new and emerging field. Monotheistic religions are very conservative about such changes to the human genome and can be considered an interference with God’s creation. Moreover, these (...) changes could cause perpetual changes to future generations. The Muslim scholars establish their decisions by addressing five foundations of Islamic law i.e. “maqāṣid al sharı̄`a”; the purposes of the law. These are dın̄, nafs, nasl, `aql and māl. To achieve this, the five principles should all be met before approval of an experiment like the Chinese embryo modifications; Qaṣd which is achieved in this case as it aims to protect the embryo from HIV. Yaqın̄ and Ḍarar were not satisfied as they require strong scientific certainty of the procedures, and evidence of safety. Ḍarūra by which the alternatives being compared; in this case more established and proven safe alternatives to protect the HIV transmission from the father are available, so this principle is not met. The final principle is `Urf, by which the social context of using any contemporary technology should be taken in consideration, and clearly this was not achieved. Collectively, germline changes are rejected from an Islamic perspective until the five principles are fulfilled. In the Chinese Twins gene editing case, there was clearly no justification or support for it according to the Muslim Jurisprudence laws. These laws and approaches can serve as an ethical checklist for such controversial research, especially in early stages of the research. (shrink)

Background Fecal microbiota transplant (FMT) is a treatment modality that involves the introduction of stool from a healthy pre-screened donor into the gastrointestinal tract of a patient. It exerts its therapeutic effects by remodeling the gut microbiota and treating microbial dysbiosis-imbalance. FMT is not regulated in Jordan, and regulatory effort for FMT therapy in Jordan, an Islamic conservative country, might be faced with unique cultural, social, religious, and ethical challenges. We aimed to assess knowledge, attitudes, and perceptions of ethical and (...) social issues of FMT use among Jordanian healthcare professionals. Methods An observational, cross-sectional study design was used to assess knowledge, attitudes, and perceptions of ethical and social issues of FMT among 300 Jordanian healthcare professionals. Results A large proportion (39 %) thought that the safety and efficacy of this technique are limited and 29.3 % thought there is no evidence to support its use. Almost all (95 %) responded that they would only perform it in certain cases, if ethically justified, and 48.3 % would use it due to treatment failure of other approaches. When reporting about reasons for not using it, 40 % reported that they would not perform it due to concerns about medical litigation, fear of infections (38 %), and lack of knowledge of long safety and efficacy (31.3 %). Interestingly, all practitioners said they would perform this procedure through the lower rather than upper gastrointestinal tract modality and the majority will protect the patient’s confidentiality via double-blinding (43.3 %). For a subset of participants (n = 100), the cultural constraints that might affect the choice of performing FMT were mainly due to donor’s religion, followed by dietary intake, and alcohol consumption. Conclusions Our healthcare practitioners are generally reluctant to use the FMT modality due to religious and ethical reasons but would consider it if there was a failure of other treatment and after taking into consideration many legislative, social, ethical and practice-based challenges including safety, efficacy and absence of guidelines. (shrink)

Neuroscience is advancing at a rapid pace, with new technologies and approaches that are creating ethical challenges not easily addressed by current ethical frameworks and guidelines. One fascinating technology is neuroimaging, especially functional Magnetic Resonance Imaging (fMRI). Although still in its infancy, fMRI is breaking new ground in neuroscience, potentially offering increased understanding of brain function. Different populations and faith traditions will likely have different reactions to these new technologies and the ethical challenges they bring with them. Muslims are approximately (...) one-fifth of world population and they have a specific and highly regulated ethical and moral code, which helps them deal with scientific advances and decision making processes in an Islamically ethical manner. From this ethical perspective, in light of the relevant tenets of Islam, neuroimaging poses various challenges. The privacy of spirituality and the thought process, the requirement to put community interest before individual interest, and emphasis on conscious confession in legal situations are Islamic concepts that can pose a challenge for the use of something intrusive such as an fMRI. Muslim moral concepts such as There shall be no harm inflicted or reciprocated in Islam and Necessities overrule prohibitions are some of the criteria that might appropriately be used to guide advancing neuroscience. Neuroscientists should be particularly prudent and well prepared in implementing neuroscience advances that are breaking new scientific and ethical ground. Neuroscientists should also be prepared to assist in setting the ethical frameworks in place in advance of what might be perceived as runaway applications of technology. (shrink)

This study aimed to evaluate Jordanian pharmacy postgraduate students’ knowledge, behavior and perception about plagiarism and why do they commit such research misconduct.This is a cross-sectional survey that was conducted in Jordan during the period between June-July 2019. The study targeted postgraduate pharmacy students from all Jordanian universities. Recruited students were asked to fill out the study questionnaire to evaluate their knowledge, behavior, and perception about plagiarism.A total of 103 postgraduate students participated in this survey, most of them were enrolled (...) in masters programs. Most of them reported that they have committed plagiarism during their studies, but this work was unintended for about 76.4% of the plagiarist.Students were asked about 12 items that represented plagiarism actions and most of postgraduate students were able to identify most of the actions as plagiarism. Overall, the mean knowledge score for students about plagiarism was 8.6 ± 2.6.Regarding students’ perceptions towards plagiarism, many students believed that plagiarizing is as bad as to steal from someone and 92.2% reported that plagiarism is considered against their ethical values.This study found a high rate of plagiarism among postgraduate pharmacy students in Jordan despite their awareness and understanding of the concept and its different forms. Academic institutions must establish formal policies to raise awareness about plagiarism, enforce and implement penalties for those who commit plagiarism. (shrink)

Research on human subjects is ethically justified when its anticipated results would ultimately benefit the society or public and not only the individuals participating in this research. Besides contributing to scientific knowledge, social benefits of scientific research may extend to all aspects of the public’s life including health, education, and security. In this paper, we aimed to discuss the social benefits principle as an ethical requirement for the conduct of scientific research in general and nursing research in particular. We critically (...) examined the current situation of nursing research in developing countries including its adherence to the social benefits principle and provided exemplars of both hindered and successful utilization of nursing research evidence in developing countries. We concluded that the utilization of nursing research evidence in clinical practice, education, and policy making is almost nonexistent and faces many challenges in most developing countries. Thus, most nursing research in developing countries are not currently meeting the social benefit principle of the ethical conduct of scientific research. We provided recommendations to promote the utilization of nursing research in evidence-based practice, nursing education, and health policy. (shrink)