Importance Informed consent is essential to ethical, rigorous research and is important to recruitment and retention in cancer trials.Objective To examine cancer clinical trial (CCT) participants’ perceptions of informed consent processes and variations in perceptions by cancer type.Design and Setting and Participants Cross-sectional survey from mixed-methods study at National Cancer Institute–designated Northeast comprehensive cancer center. Open-ended and forced-choice items addressed: (1) enrollment and informed consent experiences and (2) decision-making processes, including risk-benefit assessment. Eligibility: CCT participant with gastro-intestinal or genitourinary, hematologic-lymphatic (...) malignancies, lung cancer, and breast or gynecological cancer (N = 334).Main Outcome Measures Percentages satisfied with consent process and information provided; and assessing participation’s perceptions of risks/benefits. Multivariable logistic or ordinal regression examined differences by cancer type.Results Most patient-participants felt well informed by the consent process (more than 90% overall and by cancer type) and. most (87.4%) reported that the consent form provided all the information they wanted, although nearly half (44.8%) reported that they read the form somewhat carefully or less. More than half (57.9%) said that talking to research staff (i.e., the consent process) had a greater impact on participation decisions than reading the consent form (2.1%). A third (31.1%) were very sure of joining in research studies before the informed consent process (almost half of lung cancer patients did—47.1%). Most patients personally assessed the risks and benefits before consenting. However, trust in physicians played an important role in the decision to enroll in CCT.Conclusions and Relevance Cancer patients rely less on written features of the informed consent process than on information obtained from the research staff and their own physicians. Research should focus on information and communication strategies that support informed consent from referring physicians, researchers, and others to improve patient risk-benefit assessment and decision-making. (shrink)

Multiteam systems are complex organizational forms comprising interdependent teams that work towards their own proximal goals within and across teams to also accomplish a shared superordinate goal. MTSs operate within high-stakes, dangerous contexts with high consequences for suboptimal performance. We answer calls for nuanced exploration and cross-context comparison of MTSs “in the wild” by leveraging the MTS action sub-phase behavioral taxonomy to determine where and how MTS failures occur. To our knowledge, this is the first study to also examine how (...) key MTS attributes influence MTS processes and performance. We conducted historiometric analysis on 40 cases of failed MTS performance across various contexts to uncover patterns of within- and between-team behaviors of failing MTSs, resulting in four themes. First, component teams of failing MTSs over-engaged in within-team alignment behaviors by enacting acting, monitoring, and recalibrating behaviors more often within than between teams. Second, failing MTSs over-focused on acting behaviors and tended to not fully enact the action sub-phase cycle. Third and fourth, boundary status and goal type exacerbated these behavioral patterns, as external and physical MTSs were less likely to enact sufficient between-team behaviors or fully enact the action sub-phase cycle compared to internal and intellectual MTSs. We propose entrainment as a mechanism for facilitating MTS performance wherein specific, cyclical behavioral patterns enacted by teams align to facilitate goal achievement via three multilevel behavioral cycles. We argue that the degree to which these cycles are aligned both between teams and with the overarching MTS goal determines whether and how an MTS fails. Our findings add nuance beyond single-context MTS studies by showing that the identified behavioral patterns hold both across contexts and almost all types of MTS action-phase behaviors. We show that these patterns vary by MTS boundary status and goal type. Our findings inform MTS training best practices, which should be structured to integrate all component teams and tailored to both MTS attributes and situation type. (shrink)

It is interesting to explore the effects of second language acquisition on anatomical change in brain at different stages for the neural structural adaptations are dynamic. Short-term Chinese training effects on brain anatomical structures in alphabetic language speakers have been already studied. However, little is known about the adaptations of the gray matter induced by acquiring Chinese language for a relatively long learning period in adult alphabetic language speakers. To explore this issue, we recruited 38 Indian overseas students in China (...) as our subjects. The learned group included 17 participants who had learned Mandarin Chinese for an average of 3.24 years and achieved intermediate Chinese language proficiency. The control group included 21 subjects who had no knowledge about Chinese. None of the participants had any experience in learning logographic and tonal language before Chinese learning. We found that the learned group had significantly greater gray matter volume in the left lingual gyrus compared with the control group; the Chinese characters’ reading accuracy was significantly and positively correlated to the GMV in the left LG and fusiform gyrus across the two groups; and in the learned group, the duration of Chinese learning was significantly and positively correlated with the GMV in the left inferior frontal gyrus after correction for multiple comparisons with small volume corrections. Our structural imaging findings are in line with the functional imaging studies reporting increased brain activation induced by Chinese acquisition in alphabetic language speakers. The regional gray matter changes reflected the additional requirements imposed by the more difficult processing of Chinese characters and tones. The present study also show that the biological bases of the adaptations induced by a relatively long period of Chinese learning were limited in the common areas for first and foreign language processing. (shrink)

In the past few decades, a lot of optimization methods have been applied in estimating the parameter of photovoltaic models and obtained better results, but these methods still have some deficiencies, such as higher time complexity and poor stability. To tackle these problems, an enhanced success history adaptive DE with greedy mutation strategy is employed to optimize parameters of PV models to propose a parameter optimization method in this paper. In the EBLSHADE, the linear population size reduction strategy is used (...) to gradually reduce population to improve the search capabilities and balance the exploitation and exploration capabilities. The less and more greedy mutation strategy is used to enhance the exploitation capability and the exploration capability. Finally, a parameter optimization method based on EBLSHADE is proposed to optimize parameters of PV models. The different PV models are selected to prove the effectiveness of the proposed method. Comparison results demonstrate that the EBLSHADE is an effective and efficient method and the parameter optimization method is beneficial to design, control, and optimize the PV systems. (shrink)

Good balance between product and service is the key in the innovative design of product service systems. In this study, the evolution route of the PSS based on Teoriya Resheniya Izobretatelskikh Zadatch ideal final result was provided. The function model of the PSS was constructed according to the service blueprint and function system diagrams. On this basis, an innovation design method of the PSS based on function incentive was established. The function incentive strategies included function synergy, function supplement, and function (...) substitution. Finally, the PSS design process of agricultural machinery based on computer-aided innovation platform was analyzed to verify this method. (shrink)

Aiming to realize rapid and efficient three-dimensional identification of substation equipment, this article proposes a new method in which the 3D identification of substation equipment is based on K-nearest neighbor classification of subspace feature vector. First of all, the article uses octree encoding to reduce and denoise the point cloud data obtained by a 3D laser scanner. Secondly, position calibration and size standardization are used for the point cloud after pretreatment. Then, the normalized point cloud is divided into a number (...) of cubes with same size. The cosine of the angle between the positive direction of z axis and a vector from the global centroid of the point cloud to the centroid of each subspace is regarded as the feature of the subspace. All cosines of subspaces constitute the feature of the point cloud. Finally, we classify the subspace feature vector by using the KNN algorithm and improve classification accuracy by using the particle swarm optimization algorithm. The simulation results show that the identification accuracy of the proposed method for unknown substation equipment is about 90% and the proposed method is applicable to low-degree losses. Apparently, this method can accurately identify 3D substation equipment. At the same time, increasing the number of subspaces will improve the accuracy; however, it will increase the recognition time. (shrink)

ObjectiveThe level of health literacy is one of the important factors affecting health outcomes. Family is an important place to shape personality traits, and people with different personalities will adopt different lifestyles, which will lead to variations in health outcomes. Therefore, this article aims to explore the relationship between health literacy and personality and its influencing factors in different family structures.MethodsThis was a cross-sectional study with 1,406 individuals. A questionnaire was utilized to measure health literacy, personality and demographic variables, including (...) family structure. Canonical correlation analysis and hierarchical multiple regression analysis were used to examine the relation between health literacy and personality traits between two types of family structure.ResultsCCA showed that the canonical correlation coefficients were 0.309 and 0.347, in two-parent family and single-parent family, respectively. The openness of personality traits exhibited the highest correlation with health literacy. Compared with the remaining personality traits, openness yielded the strongest effect in two types of family structure, respectively. Education and monthly income were significantly associated with health literacy.ConclusionOur results support the relation between health literacy and personality traits in two types of family structure. (shrink)

Functional language has been used in many multinational corporations as a way to overcome the problems caused by the coexistence of multiple languages in the workplace. The existing literature has explored the importance, adoption, and effectiveness of functional language. Yet, how functional language shapes host country employees’ moral cognition and behavior is insufficiently researched. Guided by the Social Identity Theory, this manuscript shows that host country employees’ functional language proficiency enhances their unethical pro-organizational behavior through their linguistic group identification and (...) moral disengagement. We tested our predictions using the data collected from 309 full-time host country employees through an online survey, and the results generally supported our hypotheses. The findings make contributions to both international management and language literature and organizational moral behavior literature. (shrink)

Circular economy is a critical approach to realize the coordinated development of society, economy, and ecological environment. Given the fact that urban is a complex system in which human beings integrate material, energy, information, and natural environment and interact and influence each other, reviewing the urban circular economy research and development could benefit for having a better and comprehensive understanding on urban complexity. Mainly based on the Chinese literature studies from 1999 to 2020, this study aims to present an in-depth (...) analysis of the research themes, policy systems, and index system of Chinaʼs urban-scale circular economy, discuss the changes and evolution trends of themes, levels, and perspectives in time series, sort out the policy systems at both the national and local levels, and analyze the design principles and application fields of indicators. Finally, we propose that future development of an urban circular economy should be built based on modern techniques, technologies, and models. The construction of development mechanism on the circular economy should be framed as “government-led, market-driven, legal norms, policy support, technological support, and public participation” and inject concepts such as “Internet +,” “sharing economy,” “Internet of Things,” and “artificial intelligence.”. (shrink)

Objective: This study aimed to test the psychometric properties of the suicide stroop task in a Chinese college population. Methods: College students who were in the 1st–4th grade, fluent in Chinese, and without color blindness were recruited from a university in Guangzhou, China from September to December 2019. Participants were administered the suicide stroop task at baseline and 1-month follow-up. Results: The suicide stroop task showed excellent internal reliability. However, the suicide stroop task did not reveal suicide-related attentional biases among (...) current suicide ideators and was not significantly associated with the severity of suicidal ideation, depression, hopelessness, nor anhedonia, indicating a lack of concurrent validity for the task. Additionally, the two-time data of interference scores could not generate intraclass correlation coefficients due to a negative average covariance among data, which indicated poor test–retest consistency for the task. Conclusion: The results of this study did not support the use of the suicide stroop task on the identification of suicidal risk among Chinese college students. It is crucial to assess the psychometric properties of behavioral measures rigorously as self-report measures before large applications in clinical and community settings. (shrink)

Background: Individuals’ information processing includes automatic and effortful processes and the latter require sustained concentration or attention and larger amounts of cognitive “capacity.” Event-related potentials reflect all neural activities that are related to a certain stimulus. Investigating ERP characteristics of effortful cognitive processing in people with schizophrenia would be helpful in further understanding the neural mechanism of schizophrenia.Methods: Both schizophrenia patients and health controls completed ERP measurements during the performance of the basic facial emotion identification test and the face-vignette task. (...) Data of ERP components, BFEIT and FVT performances were analyzed.Results: Schizophrenia patients’ accuracies of face emotion detection in the BFEIT and vignette emotion detection in the FVT were both significantly worse than the performance of the HC group. Repeated-measures ANOVAs performed on mean amplitudes and latencies revealed that the interaction effect for group × experiment × site was significant for N250 amplitude. In FVT experiment, N250 amplitudes at prefrontal and frontal sites in schizophrenia group were larger than those of HC group; the maximum N250 amplitude was present at the prefrontal site in both the groups. For N250 latency, the interaction effect for group × experiment was significant; N250 latencies in the schizophrenia group were longer than those of the HC group.Conclusion: Schizophrenia patients present effortful cognitive processing dysfunctions which reflect in abnormal ERP components, especially N250 at prefrontal cortex and frontal cortex sites. These findings have important implications for further clarifying the neural mechanism of effortful cognitive processing deficits in schizophrenia. (shrink)

The outbreak of the COVID-19 epidemic has promoted the popularity of online learning, but has also exposed some problems, such as a lack of interaction, resulting in loneliness. Against this background, students' attitudes toward peer interaction may have become even more important. In order to explore the impact of attitude toward peer interaction on students' mindset including online learning motivation and critical thinking practice that could affect their problem-solving self-efficacy during the COVID-19 pandemic, we developed and administered a questionnaire, receiving (...) 1,596 valid responses. The reliability and validity of the questionnaire were re-tested, and structural equation modeling was applied. It was found that attitude toward peer interaction could positively predict middle school students' online learning motivation and critical thinking. Learning motivation and critical thinking also positively supported problem-solving self-efficacy. It is expected that the results of this study can be a reference for teachers to adopt student-centered online learning in problem solving courses. (shrink)

Security issue against different attacks is the core topic of cyberphysical systems. In this paper, optimal control theory, reinforcement learning, and neural networks are integrated to provide a brief overview of optimal robust control strategies for a benchmark power system. First, the benchmark power system models with actuator and sensor attacks are considered. Second, we investigate the optimal control issue for the nominal system and review the state-of-the-art RL methods along with the NN implementation. Third, we propose several robust control (...) strategies for different types of cyberphysical attacks via the optimal control design, and stability proofs are derived through Lyapunov theory. Furthermore, the stability analysis with the NN approximation error, which is rarely discussed in the previous works, is studied in this paper. Finally, two different simulation examples demonstrate the effectiveness of our proposed methods. (shrink)

Migraine is a chronic and idiopathic disorder leading to cognitive and affective problems. However, the neural basis of migraine without aura is still unclear. In this study, dynamic amplitude of low-frequency fluctuations analyses were performed in 21 patients with migraine without aura and 21 gender- and age-matched healthy controls to identify the voxel-level abnormal functional dynamics. Significantly decreased dALFF in the bilateral anterior insula, bilateral lateral orbitofrontal cortex, bilateral medial prefrontal cortex, bilateral anterior cingulate cortex, and left middle frontal cortex (...) were found in patients with migraine without aura. The dALFF values in the anterior cingulate cortex were negatively correlated with pain intensity, i.e., visual analog scale. Finally, support vector machine was used to classify patients with migraine without aura from healthy controls and achieved an accuracy of 83.33%, sensitivity of 90.48%, and specificity of 76.19%. Our findings provide the evidence that migraine influences the brain functional activity dynamics and reveal the neural basis for migraine, which could facilitate understanding the neuropathology of migraine and future treatment. (shrink)

張載思想在當代儒學界引發熱烈論辯， 他是「理學宗師」？還是「氣學之祖」？ 是「唯物論／唯氣論」者？ 還是「即存有即活動」的儒家「心性論」、「道德的形上學」？ 針鋒相對的各種詮釋，使得張載格外具有研究趣味， 也展現他在當代儒學上的學術潛力。 《當代張載學》對張載的關懷集中在心性論與氣化論的交涉之上。作為北宋理學宗師，如同牟宗三以「天道性命相貫通」為張載的中心課題，唐君毅以「人道合天道之道」標示橫渠學性格，天、道、性、心的確是張載經常使用的 核心語詞，張載學乃是儒家傳統意義下的心性論與道德形上學。然而在心性論之外，張載同時使用大量的氣論語言，並且經常在氣化流行中説明世界誠明、物與無妄。由此形成的大有哲學，正是對抗佛老的利器。切割大量氣論， 無疑違反《正蒙》初心。「太虛即氣」正是張載刻意把氣帶入天道性命論域的新哲學命題。 可惜的是，理學內部高舉〈西銘〉，貶抑《正蒙》，「以氣說道」成為對張載經常使用的批評。相較於張載在理學史上未被善待的命運，一九四九年後唯物論氣學與新儒家心性論，或晚近新儒家心性論與先天型氣學的論辯，張載 卻是一重要戰場。當中牽涉對氣的理解，也摻雜政治對立因素，並涉及儒學典範的挑戰。一個張載，多種面貌，其間的拮抗張力使當代張載研究更有挑戰性。張載強調兩端一致、兼體無累，本書相信不僅唯心、唯物對立框架不適 用於張載，也認為心性論與氣化論不必然是二擇一的選題。張載具有打破二元框架、平視心物的潛力，此有待於重新檢證其氣學性格。.

內容簡介 儒學不應僅是「思辯哲學」或「實踐理論」。從「半日靜坐，半日讀書」到當代身體觀，透過理學工夫論研究，反思儒學進入現代西方學術之轉譯過程，所產生的實踐脫落，召喚逐漸被學院哲學遺忘的實踐向度。 本書是一部探討宋明理學工夫論的著作，雖概括不同時代理學家，但貫穿其間的是儒學作為「實踐之學」的基本信念。儒學現代化過程中，在學科分類下被勉強劃入「哲學」學門，但哲學家一向擅長以理論的方式探討實踐，卻往 往無法自己親自實踐。當代儒學也出現一個難題：學術化的儒家哲學如何「實踐」？如何不僅成為「思辯哲學」或「實踐理論」？如何避免「實踐的脫落」？此實是儒學現代化、學術化下的一項挑戰。 藉著回顧理學傳統的修養方法，尋找返本開新的可能。本書關注理學工夫的具體實踐與操作方法，如何被運作、展開；此訴求下，靜坐、讀書與與身體觀，是本書比較集中探討的理學工夫論面向。將工夫論研究，由思想文獻中靜 態結構描述的「實踐理論」，返回實修實證的動態歷程之展現。使儒家哲學研究從心性形上學，往身體向度落實，發展成完整的「身心之學」。 名人推薦 理學做為成德之學，向來與生命實踐密不可分。實踐工夫成為理學家日常性功課，甚至以證本體為生命大事，那種古典求道精神的實踐神聖性，在當今學術專技化的客觀年代，已逐漸成為一種實踐理論之客觀研究。而當存在體驗 化為抽象理論時，理學原初最濃厚的實踐動能與召喚力道，是否也將靈光消逝？本書作者的初發心，便具有這種存在的憂心與感受。換言之，身為現代的學者，作者仍懷有強烈的求道之古典關懷。本書的基本主題關涉：靜坐與讀 書這兩種工夫論的辯證，而除了心性修養的傳統論述以外，作者亦吸收當代的身體實踐觀點，企圖更為完整地描述理學家身心一體轉化的體證內涵。現今從事理學工夫理論的研究者不算少，但在理論與實踐之間尋尋覓覓者已不多 ，在這種儒門淡泊的工夫遺忘的現代氣氛下，作者的懷古初心尤為可貴，其研究成果也值得觀察。──賴錫三╱中山大學中文系教授 現代儒學研究，儒家的工夫論常被本體論取代，而呈失語現象。此書真正立基於工夫實踐的立場，可做為現今儒者內聖學道德實踐之重要參考著作。──廖俊裕╱南華大學生死學系副教授.

本书收集了著名哲学家、伦理学家周辅成先生的重要文章，分两卷编辑，包括了《歌德对于哲学的见解》、《论莎士比亚的人格》、《亚里士多德的伦理学》、《论当前农村社会的道德风气》等文章。.

Shang. Qiu shi lun ji -- Xia. Xu qiu shi lun ji.

One of the most significant challenges in the application of brain-computer interfaces is the large performance variation, which often occurs over time or across users. Recent evidence suggests that the physiological states may explain this performance variation in BCI, however, the underlying neurophysiological mechanism is unclear. In this study, we conducted a seven-session motor-imagery experiment on 20 healthy subjects to investigate the neurophysiological mechanism on the performance variation. The classification accuracy was calculated offline by common spatial pattern and support vector (...) machine algorithms to measure the MI performance of each subject and session. Relative Power values from different rhythms and task stages were used to reflect the physiological states and their correlation with the BCI performance was investigated. Results showed that the alpha band RP from the supplementary motor area within a few seconds before MI was positively correlated with performance. Besides, the changes of RP between task and pre-task stage from theta, alpha, and gamma band were also found to be correlated with performance both across time and subjects. These findings reveal a neurophysiological manifestation of the performance variations, and would further provide a way to improve the BCI performance. (shrink)

Your letter has been received. Please give my regards to all the comrades-in-arms of Rebel Command Post of Henan Province [Henanzhaozhong]! Please also convey our deepest condolences to those comrades-in-arms who shed blood and sacrificed their lives while fighting under difficult and harsh circumstances.