The return of genetic research results after death in the pediatric setting comes with unique complexities. Researchers must determine which results and through which processes results are returned. This paper discusses the experience over 15 years in pediatric cancer genetics research of returning research results after the death of a child and proposes a preventive ethics approach to protocol development in order to improve the quality of return of results in pediatric genomic settings.

In response to the discussion between William W. Morgan and Annette Kolodny in the Summer 1976 issue of Critical Inquiry I would like to address the issue of separating judgments based on feminism as an ideology from purely aesthetic judgments. Peripherally this included the issue of "prescriptive criticism," so labeled by Cheri Register in Feminist Literary Criticism: Explorations in Theory.1 In the same book, as Kolodny points out,2 I called for criticism that exists in the "prophetic mode." Kolodny indicates reservations (...) about both concepts without fully exploring the issue. I would like to explain my statement here and to explore further the issue of feminism and aesthetics. When I called for criticism in the prophetic mode, I did not intend to promote an idea of the critic as ideological prophet. Rather, as I explain in the context from which the term is taken,3 I am speaking of the engaged scholar who is concerned to influence the future by her/his work today. S/he chooses her/his work with an eye to encourage political and social changes. Obviously, for a feminist this translates into a concern for a future in which women will be free from many of the restrictions that have held them down in the past. Much feminist criticism is thus corrective criticism designed to redress the imbalance in current literary curricula, and more generally to reintroduce "the feminine" into the public culture. · 1. Cheri Register, "American Feminist Literary Criticism: A Bibliographical Introduction ," Feminist Literary Criticism: Explorations in Theory, ed. Josephine Donovan pp. 11-24.· 2. Annette Kolodny, "The Feminist as Literary Critic," Critical Inquiry 2 : 828.· 3. Josephine Donovan, "Critical Re-Vision," Feminist Literary Criticism, p. 81, n. 2. Josephine Donovan, currently working on a literary biography of Sarah Orne Jewett, has written "Feminist Style Criticism," "Sexual Politics in the Short Stories of Sylvia Plath," and has edited Feminist Literary Criticism: Explorations in Theory. Although the occasion for this response was the exchange between Annette Kolodny and William W. Morgan , the questions raised by Ms. Donovan have some bearing on other topics discussed in Critical Inquiry—e.g., the nature of accepted canons in the arts . In addition the question of how we may interpret literary works from the past that contain currently unacceptable representations of women has implications as well for how we respond to "objectionable" representations of ethnic and religious groups and even of social classes. The editors expect to see these issues explored further in the future. (shrink)

The prospect of using genome technologies to modify the human germline has raised profound moral disagreement but also emphasizes the need for wide-ranging discussion and a well-informed policy response. The Hinxton Group brought together scientists, ethicists, policymakers, and journal editors for an international, interdisciplinary meeting on this subject. This consensus statement formulated by the group calls for support of genome editing research and the development of a scientific roadmap for safety and efficacy; recognizes the ethical challenges involved in clinical reproductive (...) applications of genome editing but, importantly, rejects the idea that human reproductive germline modification is necessarily morally unacceptable; and highlights the importance of meaningful engagement in discussions of genome editing and the development of regulation and oversight mechanisms to govern future uses of such technologies. (shrink)

Background Over the last decade, the return of results (ROR) in precision medicine research (PMR) has become increasingly routine. Calls for individual rights to research results have extended the “duty to report” from clinically useful genetic information to traits and ancestry results. ROR has thus been reframed as inherently beneficial to research participants, without a needed focus on who benefits and how. This paper addresses this gap, particularly in the context of PMR aimed at increasing participant diversity, by providing investigator (...) and researcher perspectives on and questions about the assumed value of ROR in PMR.Methods Semi-structured interviews with a purposive sample of investigators and researchers across federally funded PMR studies in three national consortia, as well as observations of study activities, focused on how PM researchers conceptualize diversity and implement inclusive practices across research stages, including navigating ROR.Results Interviewees (1) validated the value of ROR as a benefit of PMR, while others (2) questioned the benefit of clinically actionable results to individuals in the absence of sufficient resources for translating findings into health care for diverse and disadvantaged populations; (3) expressed uncertainties in applying the presumed value of ROR as a benefit for non-clinical results; and (4) and debated when the promise of the value of ROR may undermine trust in PMR, and divert efforts to return value beyond ROR.Conclusions Conceptualizations of diversity and inclusion among PM researchers and investigators raise unique ethical questions where unexamined assumptions of the value of ROR inform study recruitment efforts to enroll minoritized and under-represented populations. A lack of consideration for resources and infrastructure necessary to translate ROR into actionable information may hinder trustworthy community-research relationships. Thus, we argue for a more intentional interrogation of ROR practices as an offer of benefit and for whom. (shrink)

In this article I describe my experience teaching a moral problems course to first-year students within a Learning Community model. I begin with the learning goals and the mechanics of both my Learning Community and my moral problems course. I then focus on the experiential learning requirement of my Learning Community which is based on a field trip model instead of a service learning model. I describe how two field trips in particular—one to an Arab American community in Brooklyn, New (...) York, and the other to a Black American community in West Harlem, New York—primed my students to more effectively engage in philosophical discussions about terrorism, war, and affirmative action. I conclude that experiential learning on a field trip model helped my students to have more sophisticated conversations about complex and emotionally charged moral issues. (shrink)

This article compares case studies to better understand how third grade teachers, serving low-income (including Title I) schools, adapted their instruction in the midst of a global pandemic to better support their students’ learning about locally-relevant civic issues. Civic perspective-taking components were embedded in the unit design with the aim of building deliberative, inclusive classrooms. The team designed lessons drawing from theories of culturally sustaining pedagogy. Using semi-structured interview data, we examined teachers’ reported thinking and perceptions about students’ needs and (...) their own struggles to deliver purposeful, equitable instruction. Findings indicate that as teachers collaboratively designed the lessons they discussed how to balance relevance and sensitivity in relation to content that mirrored students lived realities. This study advances our understanding of what challenges teachers overcome to integrate culturally-sustaining practices in their social studies instruction. (shrink)

In Aaron and Bachalo's work, Doctor Stephen Strange exemplifies the characteristics and methods of the natural philosophers in clashes with his mystical enemies, Lord Imperator and the Empirikul. It's easy to be distracted by Doctor Strange's fancy spells, unique job title, or flashy cape, but we should also recognize that he is a Sorcerer Supreme, who demonstrates both discipline and intellect. Like the historical philosopher‐scientists, Doctor Strange studies metaphysics and its relationship to the physical world. When intellectuals began to challenge (...) Aristotle's teleological world‐view, they faced opposition from both the Catholic Church, who found Aristotle's views consistent with scripture, and the scientific community. Historian Peter Dear's book Revolutionizing the Sciences helps situate the work of ancient philosophers, like Aristotle, in the context of the history of the scientific revolution. (shrink)

William Storm reinterprets the concept of the tragic as both a fundamental human condition and an aesthetic process in dramatic art. He proposes an original theoretical relation between a generative and consistent tragic ground and complex characterization patterns. For Storm, it is the dismemberment of character, not the death, that is the signature mark of tragic drama. Basing his theory in the sparagmos, the dismembering rite associated with Dionysus, Storm identifies a rending tendency that transcends the ancient Greek setting and (...) can be recognized transhistorically. The dramatic character in any era who suffers the tragic fate must do so in the manner of the ancient god of theater: the depicted self is torn apart, figuratively if not literally, psychologically if not physically. Storm argues that a newly objectified concept of the tragic can prove more useful critically and diagnostically than the traditional and more subjective tragic "vision." Further, he develops a theory of the tragic field, a model for the connective and cumulative activity that brings about the distinctive Dionysian effect upon character. His theory is supported with case studies from Agamemnon and Iphigenia in Aulis, King Lear, and The Seagull. Storm's examination of the dramatic form of tragedy and the existential questions it raises is sensitive to both their universal relevance and their historical particularity. (shrink)

Community-based learning is one way to bring discussions about diversity and inclusion into the philosophy classroom, but it can have unintended, negative consequences if it is not carefully planned. This article is divided into four sections that utilize courses and projects in which I have participated, as both co-architect and instructor, to discuss potential negative outcomes and how to avoid them. The first section introduces the projects and courses. The second section discusses practices that nurture positive relationships between institutions of (...) higher education and communities, and pedagogical strategies to prevent reinforcing negative student perceptions about vulnerable communities. The third section discusses how curricular and pedagogical choices can challenge privilege and power both in the classroom and community experience. The final section focuses on what to do when a student resists the learning experience. I conclude with a brief reflection about the community side of this partnership. (shrink)

Throughout the COVID-19 pandemic, the concept of solidarity has been invoked frequently. Much interest has centred around how citizens and communities support one another during times of uncertainty. Yet, empirical research which accounts and understands citizen’s views on pandemic solidarity, or their actual practices has remained limited. Drawing upon the analysis of data from 35 qualitative interviews, this article investigates how residents in England and Scotland enacted, understood, or criticised (the lack of) solidarity during the first national lockdown in the (...) United Kingdom in April 2020—at a time when media celebrated solidarity as being at an all-time high. It finds that although solidarity was practiced by some people, the perceived lack of solidarity was just as pronounced. We conclude that despite frequent mobilisations of solidarity by policy makers and other public actors, actual practices of solidarity are poorly understood—despite the importance of solidarity for public health and policy. (shrink)

In season one of True Detective, people watch Rustin Cohle evolve from a man who is slowly suffocating under the weight of the world to one who can shoulder it. His metamorphosis is existential. By the end of the season, when he proclaims that the "light is winning", Cohle has arrived. Cohle has had enough of his life; he is trapped in his despair and choking on its poison. Throughout the first season of True Detective, Cohle is the shepherd who (...) is choking on all that is bitter and ugly in the world. He is struggling to find the strength to kill the snake. The snake represents the necessity of affirming all aspects of life and willing them eternally. This leads us to Errol Childress. He is the hyperbolic monster at the end of the dream; he is the specter of nihilism and suffering. Their encounter ends with a violent, crippling battle and Childress' death. (shrink)

The authors conducted a baseline survey of baccalaureate and graduate degree health humanities programs in the United States and Canada. The object of the survey was to formally assess the current state of the field, to gauge what kind of resources individual programs are receiving, and to assess their self-identified needs to become or remain programmatically sustainable, including their views on the potential benefits of program accreditation. A 56-question baseline survey was sent to 111 institutions with baccalaureate programs and 20 (...) institutions with graduate programs. Respondents were asked about three areas: (1) program administration (managing unit, paid director, faculty lines, paid staff, funding sources); (2) educational program (curricular structure, CIP code usage, completion rates); and (3) views on accreditation for the field. A clear majority of respondents agreed that some form of accreditation or consultation service could address resource and sustainability issues. Overall, the survey responses to staffing, curricular structure, and support suggest the need for developing a sustainable infrastructure for health humanities. (shrink)

With attractive and scantily clad female characters, Zeus as a philandering womanizer, the First Born as a hyper‐masculine war monger, and Hera as a jealous wife blaming other women for her husband's infidelities, Wonder Woman (the New 52 series) confirms some age old stereotypes about men and women. But, Wonder Woman (the New 52) also challenges some traditional gender stereotypes. The end of the twentieth and beginning of the twenty‐first century have witnessed great strides in gender equality for, among others, (...) heterosexual women and members of the LGBTQ community. In one of the most important early books in twentieth‐century feminist philosophy, The Second Sex, philosopher and novelist Simone de Beauvoir explores women's inequality to men. The chapter considers the transformation of Hera throughout Wonder Woman (the New 52) as an existential movement from immanence to transcendence. (shrink)

Lex Luthor despises Superman. He obsesses about Superman. He tries to kill Superman. Luthor takes existentialism to the extreme, though, rejecting ethics and becoming an anti‐hero. In Superman: Secret Origin, Luthor is presented as self‐directed from an early age. Friedrich Nietzsche can help us understand Luthor as an iconoclast, literally one who breaks sacred images. Luthor also explains why he is so obsessed with bringing down Superman. Luthor thinks that Superman interferes with people viewing their lives as an existential project. (...) Lex Luthor underscores the complexities of existentialist philosophy. While he is creative, self‐determined, and autonomous, he is also completely immoral. His willingness to sacrifice anything or anyone takes existentialism to an extreme that Nietzsche, Sartre, and Kierkegaard would reject. And so, we are left to wonder: is Lex Luthor an evil genius and an abomination to existentialism, or might he be a true evolution of what existentialism can become. (shrink)

Despite theorisation and consistent Pracademic (academics who are also practitioners) contributions to the concepts of truth-telling and decolonising epistemologies in the fields of activist research, there remains ongoing need for articulating the everyday praxis and positionality of empirical work. This paper considers the practice of two intercultural Australian-based practitioners’ examination of the ethical practices towards decolonising praxis as a contributor to third-space youth development which considers the space between participants. First Nations terminology is drawn on to explore the empirical nature (...) of third space theory (Bhabha) acknowledging the social construct of hybrid identities within individuals and communities’ personhood. Through exploring Indigenous inquiry as a contributor to third-space youth development, this paper argues that co-creation of knowledge amongst young people and practitioners considers a third space which can allow for deeper understandings of intercultural work and power dynamics. This article provides the opportunity to further explore a critical analysis of the challenges and possibilities of practitioners/pracademics working towards a decolonising journey which has implications for the ethics of youth work practice globally. (shrink)

A paradigm shift in public health and medicine has broadened the field from a singular focus on the ill effects of negative states and psychopathology to an expanded view that examines protective psychological assets that may promote improved physical health and longevity. We summarize recent evidence of the link between psychological well-being and physical health, with particular attention to outcomes of mortality and chronic disease incidence and progression. Within this evolving discipline there remain controversies and lessons to be learned. We (...) discuss measurement-related challenges, concerns about the quality of the evidence, and other shortcomings in the field, along with a brief discussion of hypothesized biobehavioral mechanisms involved. Finally, we suggest next steps to move the field forward. (shrink)

Bodily methodologies that engage with the affective, rhythmic, and temporal dimensions of movement have altered the landscape of social science and humanities research. Walking is one such methodology by which scholars have examined vital, sensory, material, and ephemeral intensities beyond the logics of representation. Extending this rich field, this article invokes the concept trans to reconceptualize walking research through theories that attend to the vitality and agency of matter, the interconnectedness between humans and non-humans, the importance of mediation and bodily (...) affect, and the necessity of acknowledging ethico-political responsibility. While theoretical and empirical research about embodied, emplaced, and sensorial relations between moving bodies and space are well developed in the field of walking studies, their entanglements become profoundly altered by theories of trans – transcorporeality, transspecies, and transmaterialities. Taking up trans theories we experiment in thinking-with a sonic art performance, Walking to the Laundromat, which probes bodily, affective, and gendered labour. (shrink)

Malformations concerning the ventral body wall constitute one of the leading categories of human birth defects and are present in about one out of every 2000 live births. Although the occurrence of these defects is relatively common, few detailed experimental studies exist on the development and closure of the ventral body wall in mouse and human. This field is further complicated by the array of theories on the pathogenesis of body wall defects and the likelihood that there is no single (...) cause for these abnormalities. In this review, we summarize what is known concerning the mechanisms of normal ventral body wall closure in humans and mice. We then outline the theories that have been proposed concerning human body wall closure abnormalities and examine the growing number of mouse mutations that impact normal ventral body wall closure. Finally, we speculate how studies in animal models such as mouse and Drosophila are beginning to provide a much‐needed mechanistic framework with which to identify and characterize the genes and tissues required for this vital aspect of human embryogenesis. BioEssays 26:1307–1321, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

To isolate, analyze and explain their most basic commitments, theories of justice typically idealize. They assume for theoretical purposes, for example, that human beings possess far greater knowledge than they do, or that society's members strictly comply with just laws. Yet because it falsifies, idealization undermines the practical applicability of an ideal theory's principles. ;Although ideal theories are unsatisfactory as they stand, their fundamental principles may be invaluable in addressing our problems of justice. From such basic principles we may derive (...) intermediate ones that bridge the gap between ideal world and real, and allow us to determine what ideal theory demands in actual circumstances. ;Going beyond others who recognize the need, but themselves offer only ideal theories, I develop a set of these intermediate principles. I examine Kant's theory of justice as a paradigm, and identify problems it cannot address because they have their source in non-ideal features, including limited knowledge, imperfect will and preexisting social injustice. I then appeal to a modified version of the perspective of the ideal citizen that Kant employs in the Rechtslehre. This modified perspective enables us to articulate principles that give effect to Kant's universal law of justice and categorical imperative in non-ideal circumstances. Illustrating its use in addressing issues such as prison reform and exclusionary zoning, I argue that augmented ideal theory can play a crucial role in our pursuit of social justice. (shrink)

The application of machine learning and artificial intelligence in healthcare domains has received much attention in recent years, yet significant questions remain about how these new tools integrate into frontline user workflow, and how their design will impact implementation. Lack of acceptance among clinicians is a major barrier to the translation of healthcare innovations into clinical practice. In this systematic review, we examine when and how clinicians are consulted about their needs and desires for clinical AI tools. Forty-five articles met (...) criteria for inclusion, of which 24 were considered design studies. The design studies used a variety of methods to solicit and gather user feedback, with interviews, surveys, and user evaluations. Our findings show that tool designers consult clinicians at various but inconsistent points during the design process, and most typically at later stages in the design cycle. We also observed a smaller amount of studies adopting a human-centered approach and where clinician input was solicited throughout the design process. A third of all studies reported on clinician trust in clinical AI algorithms and tools. The surveyed articles did not universally report validation against the “gold standard” of clinical expertise or provide detailed descriptions of the algorithms or computational methods used in their work. To realize the full potential of AI tools within healthcare settings, our review suggests there are opportunities to more thoroughly integrate frontline users’ needs and feedback in the design process. (shrink)

This study examines the impact of Fair Trade on the sustainability of coffee growing. To examine sustainability we use an ethnographic approach, interviewingproducers and their associated buyers working in Fair Trade organizations in Chiapas Mexico. We focus on social, economic and ecological dimensions of the producers’ and buyers’ experience.

In March 2020, the World Health Organization declared the disease caused by SARS-CoV-2 coronavirus “pandemic.” To reduce the risk of contamination, many countries have ordered a lockdown characterized by social distancing and restrictive isolation measures. While the lockdown has proven to be quite effective in terms of physical health, little is known about its impact on couple satisfaction in a dyadic perspective. The current research was a 4-waves longitudinal study with the objective to examine the trajectory of couple satisfaction during (...) the lockdown with a dyadic perspective, including the presence of children at home, the number of hours spent together, and the duration of the relationship as time-invariant predictors and the partner’s couple satisfaction trajectory as a time-varying covariate. Results showed positive intraindividual changes in couple satisfaction during the lockdown, especially an increase in partners’ effectiveness for resolving couple conflicts and a decrease in partners’ aggressiveness. Partners had also perceived the influence of the lockdown as more and more positive over time on couple and family functioning. Finally, the couple satisfaction of both partners changed in tandem during the lockdown: The perception of the couple relationship seems to similarly evolve between partners. (shrink)

Mastery imagery (i.e., images of being in control and coping in difficult situations) is used to regulate anxiety. The ability to image this content is associated with trait confidence and anxiety, but research examining mastery imagery ability's association with confidence and anxiety in response to a stressful event is scant. The present study examined whether trait mastery imagery ability mediated the relationship between confidence and anxiety, and the subsequent associations on performance in response to an acute psychological stress. Participants (N= (...) 130; 55% male;Mage= 19.94 years;SD= 1.07 years) completed assessments of mastery imagery ability and engaged in a standardized acute psychological stress task. Immediately prior to the task, confidence, cognitive and somatic anxiety intensity, and interpretation of anxiety symptoms regarding the task were assessed. Path analyses supported a model whereby mastery imagery ability mediated the relationship between confidence and cognitive and somatic anxiety interpretation. Greater mastery imagery ability and confidence were both directly associated with better performance on the stress task. Mastery imagery ability may help individuals experience more facilitative anxiety and perform better during stressful tasks. Improving mastery imagery ability by enhancing self-confidence may help individuals successfully cope with anxiety elicited during stressful situations. (shrink)

This reply addresses observations of Drs. Larsen, Kruse, and Sweeny, and Scherer in their reviews of our published work on the link between positive psychological assets and outcomes of physical health. Inspired by Obama’s Precision Medicine Initiative we argue that the interplay between the emotion spectrum and health is likely a complex and heterogeneous amalgam of known and yet unidentified elements melding at the individual level. When exploring the emotion–health link, researchers are challenged to grapple with complex system models by (...) considering multiple hierarchies of information that span individual-level factors, genetic blueprints, and cultural and environmental context. Research is needed to more fully elucidate the mechanism through which emotion influences health, with careful consideration of differences across race/ethnicity, culture, and context. (shrink)

Here I set the stage for developing a Kantian account of punishment attuned to social and economic injustice and to the need for prison reform. I argue that we cannot appreciate Kant's own discussion of punishment unless we read it in light of the theory of justice of which it is a part and the fundamental commitments of that theory to freedom, autonomy and equality. As important, we cannot properly evaluate Kant's advocacy of the law of retribution unless we recognize (...) his theory of justice as an ideal theory. Once we understand both Kant's larger account of justice and its relationship to his less basic commitments, we discover grounds to accept that larger theory, but reject components like the law of retribution with their basis in empirical conclusions we may not share with Kant. We also open the way to develop an account of punishment responsive to social circumstances. (shrink)

BackgroundSocial support plays an important role for health outcomes. Support for those living with chronic conditions may be particularly important for their health, and even for their survival. The role of support for the survival of cancer patients after receiving an allogeneic hematopoietic cell transplant is understudied. To better understand the link between survival and support, as well as different sources and functions of support, we conducted two studies in alloHCT patients. First, we examined whether social support is related to (...) survival. Second, we examined who provides which support and which specific support-related functions and tasks are fulfilled by lay caregivers and healthcare professionals.MethodsIn Study 1, we conducted a retrospective chart review of alloHCT patients and registered availability of a dedicated lay caregiver and survival. In Study 2, we prospectively followed patients after alloHCT from the same hospital, partly overlapping from Study 1, who shared their experiences of support from lay caregivers and healthcare providers in semi-structured in-depth interviews 3 to 6 months after their first hospital discharge.ResultsPatients with a dedicated caregiver had a higher probability of surviving to 100 days than patients without a caregiver, OR = 2.84, p = 0.042. Study 2 demonstrated the importance of post-transplant support due to patients’ emotional needs and complex self-care regimen. The role of lay caregivers extended to many areas of patients’ daily lives, including support for attending doctor’s appointments, managing medications and financial tasks, physical distancing, and maintaining strict dietary requirements. Healthcare providers mainly fulfilled medical needs and provided informational support, while lay caregivers were the main source of emotional and practical support.ConclusionThe findings highlight the importance of studying support from lay caregivers as well as healthcare providers, to better understand how they work together to support patients’ adherence to recommended self-care and survival. (shrink)

These meditations, which begin with Stephan Schwartz and Mark Schroll's contested and contesting histories of the lineage and founding of the Society for the Anthropology of Consciousness (below), contribute to the imagining of what Bethe Hagens calls "the relatively new interdisciplinary field of anthropology of consciousness.” Ethnographic vignettes from fieldwork of anthropologists, as well as fieldwork of students studying that fieldwork, highlight the paradox of anthropology's secularism and invite the reader, through the reading and writing of the text itself, to (...) participate in the practices of consciousness described. Using Schwartz's metaphor of "boulders in the stream,” these practices, and the modes of consciousness they invoke, serve as boulders that readers must swim around, or hop from, secularist anthropology through cyborg anthropology to an anthropology of consciousness itself. (shrink)

1 Evidence-based policy requires researchers to provide the answers to ecological questions that are of interest to policy makers. To find out what those questions are in the UK, representatives from 28 organizations involved in policy, together with scientists from 10 academic institutions, were asked to generate a list of questions from their organizations. 2 During a 2-day workshop the initial list of 1003 questions generated from consulting at least 654 policy makers and academics was used as a basis for (...) generating a short list of 100 questions of significant policy relevance. Short-listing was decided on the basis of the preferences of the representatives from the policy-led organizations. 3 The areas covered included most major issues of environmental concern in the UK, including agriculture, marine fisheries, climate change, ecosystem function and land management. 4 The most striking outcome was the preference for general questions rather than narrow ones. The reason is that policy is driven by broad issues rather than specific ones. In contrast, scientists are frequently best equipped to answer specific questions. This means that it may be necessary to extract the underpinning specific question before researchers can proceed. 5 Synthesis and applications. Greater communication between policy makers and scientists is required in order to ensure that applied ecologists are dealing with issues in a way that can feed into policy. It is particularly important that applied ecologists emphasize the generic value of their work wherever possible. (shrink)

It would be hard to find a more effective visual source for understanding the political ideology that underscores Dante's relationship to Boniface VIII in the Divina Commedia than the frescoes that line the walls of the Oratorio di San Silvestro in the Basilica of the Santi Quattro Coronati in Rome. These frescoes, which depict episodes from the life of St. Sylvester and his relationship to the emperor Constantine, express as their clear subtext the thirteenth-century papacy's view of the proper relationship (...) between ecclesiastical and secular power . Their vivid dramatization of these events synthesizes and, more importantly, interprets two well-known literary sources: the life of St. Sylvester that was thought to have been composed by Eusebius of Caesarea and the text of the Donation of Constantine, the Constitutum Constantini. The account of the life of St. Sylvester that is contained in the Golden Legend also provides a readily accessible point of reference for the cycle, since it is roughly contemporaneous with it and is itself a compilation based on these earlier texts. (shrink)

Here Samuel Fleischacker undertakes an ambitious task. Primarily he aims to develop and defend an account of political liberty importantly distinct from the alternatives Isaiah Berlin made famous. Moreover, he promises to enunciate this account by appeal to Kant and Adam Smith and to demonstrate its practical strengths by comparison with the work of several contemporary political theorists, Rawls most significant among them.

ABSTRACT To date, over forty-seven studies have examined the antecedents and outcomes of Moral Disengagement mechanisms used to rationalize unethical behavior. However, none have examined its relationship with mindful awareness, either as a trait or set of everyday applications. Our study demonstrates that trait mindfulness is negatively correlated with all MD mechanisms. The tendency to apply decentering and relaxation is positively correlated with all MD mechanisms while stopping and reappraisal trend toward positive relationships and savoring shows no correlation. We discuss (...) potential reasons for these disparate relationships and implications for mindfulness-based interventions in the workplace. (shrink)

Background:The severity of the Coronavirus pandemic has led to lockdowns in different countries to reduce the spread of the infection. These lockdown restrictions are likely to be detrimental to mental health and well-being in adolescents. Physical activity can be beneficial for mental health and well-being; however, research has yet to examine associations between adolescent physical activity and mental health and well-being during lockdown.Purpose:Examine the effects of adolescent perceived Coronavirus prevalence and fear on mental health and well-being and investigate the extent (...) to which physical activity can be a protective factor against these concerns.Methods:During United Kingdom lockdown restrictions, 165 participants (100 female, aged 13–19) completed an online questionnaire assessing perceived Coronavirus prevalence and fear, physical activity, and indicators of mental health and well-being (stress, anxiety, depression, fatigue, vitality, and perceived health). Separate hierarchical multiple linear regression analyses (with age, gender, perceived Coronavirus prevalence, and fear entered in step 1, and physical activity in step 2) were run to predict each well-being outcome.Results:Regression analyses indicated that in general, while Coronavirus fear was a negative predictor, physical activity was a positive and stronger predictor of enhanced mental health and well-being outcomes.Conclusion:Findings suggest that physical activity during the Coronavirus pandemic can counteract the negative effects of Coronavirus fear on adolescent mental health and well-being. Therefore, physical activity should be promoted during lockdown to support good mental health and well-being. (shrink)

This article presents texts recovered by post-processing of multispectral images from the fifth- or sixth-century underwriting of the palimpsest Codex Climaci Rescriptus. Texts identified include the Anonymous II Proemium to Aratus’ Phaenomena, parts of Eratosthenes’ Catasterisms, Aratus’ Phaenomena lines 71–4 and 282–99 and previously unknown text, including some of the earliest astronomical measurements to survive in any Greek manuscript. Codex Climaci Rescriptus also contains at least three astronomical drawings. These appear to form part of an illustrated manuscript, with considerable textual (...) value not merely on the basis of its age but also of its readings. The manuscript undertexts show significant overlap with the Φ Edition, postulated as ancestor of the various Latin Aratea. (shrink)