Recentemente, sulla rivista «Nature», i progressi empirici della teoria dell’evoluzione sono stati descritti nei termini di un confronto tra «riformisti», i quali auspicano una revisione dell’approccio neodarwiniano standard attraverso l’inclusione di fattori e processi fino ad ora trascurati, e «conservatori», secondo i quali l’attuale programma di ricerca evoluzionistico, basato sulla variazione genetica e sulla selezione naturale, «va bene così». Il dissidio, che concerne principalmente il problema del riduzionismo genetico, sembra non portare a nessun risultato. I riformisti mettono in luce dei (...) fattori molto importanti, ma paiono non portare ancora nessuna proposta coerente quanto alla struttura di questa versione estesa della teoria evoluzionistica a venire. I conservatori si mettono sulla difensiva, facendo affidamento soltanto su quelle aggiunte che non modificano il nucleo neodarwiniano quanto ai suoi tratti essenziali, mantenendolo ben saldo nei vecchi connotati. Analizziamo qui il suddetto dibattito, proponendone un’interpretazione. La biologia evoluzionistica è un campo di ricerche in rapida espansione. L’oggetto del contendere è la modalità di estendere e aggiornare il nucleo centrale dell’eredità darwiniana. La nostra ipotesi è che, nel campo della biologia evoluzionistica attuale, si stia producendo un avanzamento del programma di ricerca, la cui struttura è composta da una serie di pattern evolutivi integrabili e compatibili tra di loro. Nel corso della sua storia la biologia evoluzionistica si è infatti accresciuta tramite l’inclusione progressiva di modelli diversi, senza che questo significasse una revisione del nucleo della teoria. La «teoria gerarchica» di Niles Eldredge è un esempio di struttura globale che si propone come fine quello di incorporare e unificare i pattern evoluzionistici attualmente accettati. (shrink)

We develop a version of a direct perception account of emotion recognition on the basis of a metaphysical claim that emotions are individuated as patterns of characteristic features. On our account, emotion recognition relies on the same type of pattern recognition as is described for object recognition. The analogy allows us to distinguish two forms of directly perceiving emotions, namely perceiving an emotion in the absence of any top-down processes, and perceiving an emotion in a way that significantly involves (...) some top-down processes ; and, in addition, an inference-based evaluation of an emotion. Our model clarifies the epistemology of emotion recognition. (shrink)

The paper addresses the formation of striking patterns within originally near-homogenous tissue, the process prototypical for embryology, and represented in particularly purist form by cut sections of hydra regenerating, by internal reorganisation of the pre-existing tissue, a complete animal with head and foot. The essential requirements are autocatalytic, self-enhancing activation, combined with inhibitory or depletion effects of wider range – “lateral inhibition”. Not only de-novo-pattern formation, but also well known, striking features of developmental regulation such as induction, inhibition, and (...) proportion regulation can be explained on this basis. The theory provides a mathematical recipe for the construction of molecular models with criteria for the necessary non-linear interactions. It has since been widely applied to different developmental processes. (shrink)

Abstract: The notion of a self-pattern, as developed in the pattern theory of self, which holds that the self is best explained in terms of the kind of reality that pertains to a dynamical pattern, acknowledges the importance of neural dynamics, but also expands the account of self to extra-neural (embodied and enactive) dynamics. The pattern theory of self, however, has been criticized for failing to explicate the dynamical relations among elements of the self-pattern; as (...) such, it seems to be nothing more than a mere list of elements. We’ll argue that the dynamics of a self-pattern are reflected in three significant and interrelated ways that allow for investigation. First, a self-pattern is reflectively reiterated in its narrative component. Second, studies of psychiatric or neurological disorders can help us understand the precise nature of the dynamical relations in a self-pattern, and how they can fail. Third, referencing predictive processing accounts, neuroscience can also help to explicate the dynamical relations that constitute the self-pattern. (shrink)

In isolated English word reading, readers have the optimal performance when their initial eye fixation is directed to the area between the beginning and word center, that is, the optimal viewing position (OVP). Thus, how well readers voluntarily direct eye gaze to this OVP during isolated word reading may be associated with reading performance. Using Eye Movement analysis with Hidden Markov Models, we discovered two representative eye movement patterns during lexical decisions through clustering, which focused at the OVP and the (...) word center, respectively. Higher eye movement similarity to the OVP-focusing pattern predicted faster lexical decision time in addition to cognitive abilities and lexical knowledge. However, the OVP-focusing pattern was associated with longer isolated single letter naming time, suggesting conflicting visual abilities required for identifying isolated letters and multi-letter words. In contrast, in both word and pseudoword naming, although clustering did not reveal an OVP-focused pattern, higher consistency of the first fixation as measured in entropy predicted faster naming time in addition to cognitive abilities and lexical knowledge. Thus, developing a consistent eye movement pattern focusing on the OVP is essential for word orthographic processing and reading fluency. This finding has important implications for interventions for reading difficulties. (shrink)

Emergence is much discussed by both philosophers and scientists. But, as noted by Mitchell (2012), there is a significant gulf; philosophers and scientists talk past each other. We contend that this is because philosophers and scientists typically mean different things by emergence, leading us to distinguish being emergence and pattern emergence. While related to distinctions offered by others between, for example, strong/weak emergence or epistemic/ontological emergence (Clayton, 2004, pp. 9–11), we argue that the being vs. pattern distinction better (...) captures what the two groups are addressing. In identifying pattern emergence as the central concern of scientists, however, we do not mean that pattern emergence is of no interest to philosophers. Rather, we argue that philosophers should attend to, and even contribute to, discussions of pattern emergence. But it is important that this discussion be distinguished, not conflated, with discussions of being emergence. In the following section we explicate the notion of being emergence and show how it has been the focus of many philosophical discussions, historical and contemporary. In section 3 we turn to pattern emergence, briefly presenting a few of the ways it figures in the discussions of scientists (and philosophers of science who contribute to these discussions in science). Finally, in sections 4 and 5, we consider the relevance of pattern emergence to several central topics in philosophy of biology: the emergence of complexity, of control, and of goal-directedness in biological systems. (shrink)

Ballard et al.'s principle of deictic coding as exemplified in the analysis of fixation patterns relies on a functional dichotomy between foveal and extrafoveal vision based on the well-known dependency of spatial resolution on eccentricity. Experimental evidence suggests that for processes of pattern learning and recognition such a dichotomy may be less warranted because its manifestation depends on the learning state of the observer. This finding calls for an explicit consideration of learning mechanisms within deictic coding schemes.

This study investigates to what extent Turkish formal complaint letters followed the ‘Problem-Solution Pattern’, and on how the writers expressed their wishes when they explained their problem and asked the authorities to amend a mistake. The study is based on a corpus of 134 Turkish complaint letters. It draws upon Flowerdew’s approach to the problem-solution pattern and the role of clause relations in this text pattern. Results showed that age-old Turkish rhetorical norms led writers’ choice of lexico-grammatical (...) patterns in reflecting politeness in order to maintain their own and the recipients’ faces. The speech acts in the ‘Problem and Solution’ parts below were hedged and impersonalized. The Turkish traditional rhetorical formula that was used in the request does not explicitly ask the reader to do something; in this way, the writers attempt to protect both their own face and that of the reader. (shrink)

Among philosophical analyses of Darwin’s Origin, a standard view says the theory presented there had no concrete observational consequences against which it might be checked. I challenge this idea with a new analysis of Darwin’s principal geographical distribution observations and how they connect to his common ancestry hypothesis.

(1991). Different forms of causation in dynamical systems: Determinism, pattern generation, and information. World Futures: Vol. 30, No. 4, pp. 221-237.

The primary argument against Rachlin's act-versus-pattern analysis of self-control is that it is wrong to think of a temptation as a solitary act while the alternative is conceived of as an element of a pattern. Either both are solitary acts or both are members of patterns, however different the patterns may be in their complexity and abstractness.

This review is focused on recent advances in our understanding of the development of coordinated cell polarity, through experiments on the Drosophila compound eye. Each eye facet (or “ommatidium”) contains a set of eight photoreceptor cells, placed so that their rhabdomeres form an asymmetric trapezoid. The array of ommatidia is organized so that these trapezoids are aligned in two mirror-image fields, dorsal and ventral to the eye midline (or “equator”). The development of this pattern depends on two systems of (...) positional information that inform the cluster of cells that will form an ommatidium of anterior/posterior (a/p) and dorsal/ventral (d/v) direction. The former (a/p) is encoded by a progressive wave of development (the morphogenetic furrow). The latter (d/v) involves molecules known to act in tissue polarity in other organs and organisms. Our understanding of the function of these molecules rests not only on their mutant phenotypes, biochemistry, and expression patterns, but also on the spatial effects when mutant patches of cells are made (genetic mosaics). BioEssays 21:275–285, 1999. © 1999 John Wiley & Sons, Inc. (shrink)

Violence against women is a growing health problem, especially when perpetrated in intimate relationships. Despite increasing attention, there is little comparative evidence on the different types of violence involved and there is a paucity of research on sexual femicides. This study examines cases of violence against women in northern Italy, focusing on sexual and non-sexual femicides and comparing them with rape that does not result in femicides. The sample included 500 women who were victims of sexual and non-sexual femicides, and (...) of rape. Results show sexual femicides mostly involved unknown victims or women who were prostitutes. Sexual femicidal offenders used improper weapons to kill their victims, acted in secluded locations, and fled the crime scene; their crime was more likely the result of predatory intentions, with antisociality and sexual deviance being the most significant factors related to this type of femicide. The criminal and violent pattern that characterized sexual femicides in this study shared significant similarities with the pattern of violence involved in rape. Rape victims were in fact mostly unknown, or involved in a brief relationship with their killer. When the victim was known it was more likely that the abuse occurred at home and in front of the woman’s children. Rapists were often under the effect of alcohol or drugs. Non-sexual femicides mainly involved known victims, and they were more often committed in the context of domestic disputes. It was not seldom that the long relationship between the victim and perpetrator was likely to be characterized by contentiousness, suggesting that the woman was often victim of an oppressive climate of emotional tension and domination. Morbid jealousy contributed to aggravating the tone of a controlling relationship. Non-sexual femicides bore more similarities to cases of rape within the pattern of intimate partner violence. Findings are discussed in terms of their implications for prevention and intervention. (shrink)

Specification denotes the type of pattern that highly improbable events must exhibit before one is entitled to attribute them to intelligence. This paper analyzes the concept of specification and shows how it applies to design detection (i.e., the detection of intelligence on the basis of circumstantial evidence). Always in the background throughout this discussion is the fundamental question of Intelligent Design (ID): Can objects, even if nothing is known about how they arose, exhibit features that reliably signal the action (...) of an intelligent cause? This paper reviews, clarifies, and extends previous work on specification in my books The Design Inference and No Free Lunch. (shrink)

A fundamental goal of biology is to understand how novel phenotypes evolved through changes in existing genes. The Dictyostelia or social amoebas represent a simple form of multicellularity, where starving cells aggregate to build fruiting structures. This review summarizes efforts to provide a framework for investigating the genetic changes that generated novel morphologies in the Dictyostelia. The foundation is a recently constructed molecular phylogeny of the Dictyostelia, which was used to examine trends in the evolution of novel forms and in (...) the divergence of genes that shape these forms. There is a major trend towards the formation of large unbranched fruiting bodies, which is correlated with the use of cyclic AMP (cAMP) as a secreted signal to coordinate cell aggregation. The role of cAMP in aggregation arose through co‐option of a pathway that originally acted to coordinate fruiting body formation. The genotypic changes that caused this innovation and the role of dynamic cAMP signaling in defining fruiting body size and pattern throughout social amoeba evolution are discussed. BioEssays 29:635–644, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

There are, I think, three distinct senses in which Rousseau uses the term “general will.” He means by it, as the nineteenth century Idealists used to point out, something very like Kant's “good will,” which all men have in common and which cannot conflict with itself. But he also means, quite as often, the Utilitarian compromise, The mean between divergent interests which takes account of all of them and satisfies as many as possible. And, thirdly, he means something like the (...) “culture pattern” of the modern anthropologists. I want to show that Green inherits this ambiguity, and that his argument in the Principles of Political Obligation is plausible only because he does not distinguish between these three meanings of “general will.”. (shrink)

Melchizedek is one of the most mysterious characters of the book of Genesis. As priest of God Almighty he blessed Abraham, the patriarch returning from war, and received tithes from him. The Epistle to the Hebrews presents Jesus Christ as high priest according to Melchizedek’s priestly order, based on God’s oath found in Psalm 110:4. While Christ’s priestly order according to Melchizedek is higher than Aaron’s priestly order, it is important to remember that Christ is greater than Melchizedek. In other (...) words, Melchizedek derives his pattern from the preexistent Christ, and not the other way around. It is the purpose of this paper to bring to attention that the superiority of the characteristics of and blessings derived from Christ’s priesthood according to Melchizedek’s order is best understood only within this frame. (shrink)

This article is devoted to the characterization of the basin of attraction of pattern solutions for some slow–fast reaction–diffusion systems with a symmetric property and an underlying oscillatory reaction part. We characterize some subsets of initial conditions that prevent the dynamical system to evolve asymptotically toward solutions which are homogeneous in space. We also perform numerical simulations that illustrate theoretical results and give rise to symmetric and non-symmetric pattern solutions. We obtain these last solutions by choosing particular random (...) initial conditions. (shrink)

ArgumentIn the United States, scientific knowledge is brought before the courts by way of testimony – the testimony of scientific experts. We argue that this expertise is best understoodfirstas related to the quality of the underlying scienceand thenin terms of who delivers it. Bloodstain pattern analysis (BPA), a contemporary forensic science, serves as the vaulting point for our exploration of objectivity as a metric for the quality of a science in judicial contexts. We argue that BPA fails to meet (...) the minimal standard set by Helen Longino’s social-procedural account of objectivity (1990, 2002). In light of some pressing issues for social-procedural accounts, we offer an infrastructural account of objectivity. This account offers what amounts to a friendly amendment to Longino’s account and adds to the ways in which we might analyze social-procedural objectivity. Finally, we address an issue that is pressing in the legal context: given that scientific knowledge is delivered by individuals, not communities, at least in U.S. courts, we (may) need a way to evaluate individual scientific and epistemic agents. We suggest a means for making this evaluation that is derived from our infrastructural account of objectivity. (shrink)

Graphic pattern (e.g. geometric design) and number-based code (e.g. digital sequencing) can store and transmit complex information more efficiently than referential modes of representation. The analysis of the two genres and their relation to one another has not advanced significantly beyond a general classification based on motion-centred geometries of symmetry. This article examines an intriguing example of patchwork coverlets from the maritime societies of Oceania, where information referencing a complex genealogical system is lodged in geometric designs. By drawing attention (...) to the interplay of graphic pattern and number-based code and its role in the knowledge economies of maritime societies, the article offers new insight into possible ways of designing a digital informational surface that captures the behaviour of an operational system, allowing both for differentiation and integration. (shrink)

Anselm’s 'Proslogion' is, as he says in its Preface, 'unum argumentum', a single line of reasoning, that builds toward the following: “that God is truly,” “that he is the highest good who needs no other,” and that he is the one “whom all things need so that they may be and may be well.” This paper attempts to shed light on how Anselm carries out the threefold task that he sets for himself and way in which his procedure brings unity (...) to the work. Although I do not provide a full account of the unity of the 'Proslogion', I lay the groundwork for such an account by reflecting on the 'Proslogion' in light of the 'Symposium', with a view to bringing a pattern of thinking present in Plato’s work to bear on the 'Proslogion'—an intertextual approach that illuminates aspects of Anselm’s thinking and reveal the rich Platonic and Neoplatonic tradition within which he was working. In the 'Symposium', one discerns a pattern of thinking that consists of three “moments”: a comic moment, a tragic moment, and a philosophic moment. To follow this pattern in one’s inquiry is, as Socrates suggests, to practice 'ta erôtica', “erotics,” the art of erotic thinking. Familiarity with this pattern of erotic thinking helps make sense of Anselm’s thinking in the 'Proslogion', and in this paper I reveal how this is so. (shrink)

Since its introduction, multivariate pattern analysis, or ‘neural decoding’, has transformed the field of cognitive neuroscience. Underlying its influence is a crucial inference, which we call the decoder’s dictum: if information can be decoded from patterns of neural activity, then this provides strong evidence about what information those patterns represent. Although the dictum is a widely held and well-motivated principle in decoding research, it has received scant philosophical attention. We critically evaluate the dictum, arguing that it is false: decodability (...) is a poor guide for revealing the content of neural representations. However, we also suggest how the dictum can be improved on, in order to better justify inferences about neural representation using MVPA. 1Introduction 2A Brief Primer on Neural Decoding: Methods, Application, and Interpretation 2.1What is multivariate pattern analysis? 2.2The informational benefits of multivariate pattern analysis 3Why the Decoder’s Dictum Is False 3.1We don’t know what information is decoded 3.2The theoretical basis for the dictum 3.3Undermining the theoretical basis 4Objections and Replies 4.1Does anyone really believe the dictum? 4.2Good decoding is not enough 4.3Predicting behaviour is not enough 5Moving beyond the Dictum 6Conclusion. (shrink)

Members of the astacin family of metalloproteinases such as human bone morphogenetic protein 1 (BMP‐1) have previously been linked to cell differentiation and pattern formation during development through a proposed role in the activation of latent growth factors of the TGF‐β superfamily. Recent finding(1) indicate that BMP‐1 is identical to pro‐collagen C‐proteinase, which is a metalloproteinase involved in extracellular matrix (ECM) formation. This observation suggests that a functional link may exist between astacin metalloproteinases, growth factors and cell differentiation and (...) pattern formation during development. Taken together, current studies indicate that BMP‐1 and possibly other astacin metalloproteinases are multifunctional enzymes that act directly on growth factors and the ECM. In combination, these dual actions would have profound effects on developmental processes. (shrink)