Dans le titre un peu provocateur de ce livre, les lecteurs reconnaîtront sans peine un clin d’œil fait à la parabole du « fils prodigue » de l’évangile de Luc. D’emblée, l’auteure explique l’intérêt de ce récit biblique : alors que le fils dont il est question, revient à la maison, domaine privilégié des femmes, la parabole ne parle jamais d’elles. L’histoire de Luc ne concerne que des hommes. Pour Élisabeth Parmentier, ce silence est significatif de l’expérience des femmes dans (...) la « maison-É... (shrink)

Since 1990, the multinational public accounting firms have all adopted flexible work arrangement policies. In part, the firms are doing this to fulfill an ethical obligation in creating an appropriate professional environment for their employees. This study examines the effect of participation in a flexible work arrangement program on an individual''s professional success and anticipated turnover as perceived by the participant''s peers and superiors. Subjects from one Big Five accounting firm read a description of a manager and answered a series (...) of questions about the likelihood of the manager''s promotion to partner, voluntary and involuntary turnover, and desirability on a job. Gender and participation in a flexible work arrangement were manipulated in a 2×2 design. The results indicate that participation in a flexible work arrangement evoked significantly more pessimistic predictions on all of the dimensions. Gender did not have an effect on the likelihood ratings. Follow-up questions about the factors that enhance and hinder individuals career success in each work scenario indicated that the perceived ability to "juggle" and the ability to "pull one''s weight" potentially affects evaluations of what it takes to be a successful professional in the financial services environment. Implications for professional and ethics practice and research are also presented. (shrink)

J’ai rencontré Marie-Jeanne Bérère à Lyon en 1994. C’était une petite femme vive, à la parole claire et précise, avec un bel accent bourguignon. Elle avait accepté une interview, à son domicile lyonnais, le 23 mars 1995. Je souhaitais la revoir pour ce numéro de CLIO, Histoire, Femmes et Sociétés sur les Chrétiennes mais elle est décédée dans l’été 2000, à 73 ans, sans avoir eu le temps de rédiger ses mémoires. Son itinéraire de femme engagée dans l’Église catholique est (...) celui d’une chrétienn... (shrink)

Flexible work arrangements (FWAs) are widely offered in public accounting as a tool to retain valued professional staff. Previous research has shown that participants in FWAs are perceived to be less likely to succeed in their careers in public accounting than individuals in public accounting who do not participate in FWAs (Cohen and Single, 2001). Research has also documented an increasing backlash against family–friendly policies in the workplace as placing unfair burdens on individuals without children. Building directly on a previous (...) study in this journal (Cohen and Single, 2001), this study addresses the issue of whether the documented perceptions toward FWA participants are the result of electing to take part in the FWA or the result of bias against employees with children. The research questions are addressed in a 3 × 2 experimental setting in which we manipulate FWA participation, along with family status and gender of a hypothetical manager in a public accounting firm. Our findings indicate that FWA participants are viewed as less likely to advance and as less committed than individuals without children or individuals who had children but who were not taking part in a FWA. Male FWA participants are viewed as less likely to succeed than female FWA participants. This effect appears to arise from a perception that FWA participants are willing to make sacrifices in their careers to accommodate family needs and thus may not be as committed to making the sacrifices perceived as necessary to meet the rigorous demands of the public accounting environment. This raises the ethical question of what could be done to change the culture in public accounting to foster a substantive support system for individuals who want to balance a family and a career. (shrink)

Flexible work arrangements (FWAs) are widely offered in public accounting as a tool to retain valued professional staff. Previous research has shown that participants in FWAs are perceived to be less likely to succeed in their careers in public accounting than individuals in public accounting who do not participate in FWAs (Cohen and Single, 2001). Research has also documented an increasing backlash against family–friendly policies in the workplace as placing unfair burdens on individuals without children. Building directly on a previous (...) study in this journal (Cohen and Single, 2001), this study addresses the issue of whether the documented perceptions toward FWA participants are the result of electing to take part in the FWA or the result of bias against employees with children. The research questions are addressed in a 3 × 2 experimental setting in which we manipulate FWA participation, along with family status and gender of a hypothetical manager in a public accounting firm. Our findings indicate that FWA participants are viewed as less likely to advance and as less committed than individuals without children or individuals who had children but who were not taking part in a FWA. Male FWA participants are viewed as less likely to succeed than female FWA participants. This effect appears to arise from a perception that FWA participants are willing to make sacrifices in their careers to accommodate family needs and thus may not be as committed to making the sacrifices perceived as necessary to meet the rigorous demands of the public accounting environment. This raises the ethical question of what could be done to change the culture in public accounting to foster a substantive support system for individuals who want to balance a family and a career. (shrink)

Outer membrane proteins (OMPs) maintain the viability of Gram‐negative bacteria by functioning as receptors, transporters, ion channels, lipases, and porins. Folding and assembly of OMPs involves synchronized action of chaperones and multi‐protein machineries which escort the highly hydrophobic polypeptides to their target outer membrane in a folding competent state. Previous studies have identified proteins and their involvement along the OMP biogenesis pathway. Yet, the mechanisms of action and the intriguing ability of all these molecular machines to work without the typical (...) cellular energy source of ATP, but solely based on thermodynamic principles, are still not well understood. Here, we highlight how different single‐molecule studies can shed additional light on the mechanisms and kinetics of OMP biogenesis. (shrink)

Although research on the mismatch negativity (MMN) has been ongoing for 40 years, the generation process of the MMN remains largely unknown. In this study, we used a single-trial EEG-fMRI coupling method which can analyse neural activity with both high temporal and high spatial resolution and thus assess the generation process of the MMN. We elicited the MMN with an auditory oddball paradigm while recording simultaneous EEG and fMRI. We divided the MMN into five equal-durational phases. Utilizing the single-trial variability (...) of the MMN, we analysed the neural generators of the five phases, thereby determining the spatiotemporal generation process of the MMN. We found two distinct bottom-up prediction error propagations: first from the auditory cortex to the motor areas and then from the auditory cortex to the inferior frontal gyrus (IFG). Our results support the regularity-violation hypothesis of MMN generation. (shrink)

Clustering plays an important role in data mining, pattern recognition, and machine learning. Then, single-valued neutrosophic sets are a useful means to describe and handle indeterminate and inconsistent information, which fuzzy sets and intuitionistic fuzzy sets cannot describe and deal with. To cluster the data represented by single-value neutrosophic information, the article proposes a single-valued neutrosophic minimum spanning tree clustering algorithm. Firstly, we defined a generalized distance measure between SVNSs. Then, we present an SVNMST clustering algorithm for clustering single-value neutrosophic (...) data based on the generalized distance measure of SVNSs. Finally, two illustrative examples are given to demonstrate the application and effectiveness of the developed approach. (shrink)

Many results have been obtained on isolated graphs and complete graphs. In this paper, a necessary and sufficient condition will be proved for a single valued neutrosophic graph to be an isolated single valued neutrosophic graph.

Majority cycling and related social choice paradoxes are often thought to threaten the meaningfulness of democracy. But deliberation can prevent majority cycles – not by inducing unanimity, which is unrealistic, but by bringing preferences closer to single-peakedness. We present the first empirical test of this hypothesis, using data from Deliberative Polls. Comparing preferences before and after deliberation, we find increases in proximity to single-peakedness. The increases are greater for lower versus higher salience issues and for individuals who seem to have (...) deliberated more versus less effectively. They are not merely a byproduct of increased substantive agreement. Our results both refine and support the idea that deliberation, by increasing proximity to single-peakedness, provides an escape from the problem of majority cycling. (shrink)

sirThe recent article by Evans in the journal on the single blind placebo in drug research is timely and its conclusions were persuasive. The basic premiss that single blind placebo “washout” periods are ethically specious was well argued and I agree that from a scientific point of view they have no valid justification. The real reasons ….

Although HIV disease has set a new model for resolving the tensions between civil liberties and public health interests, with an unprecedented commitment to individual privacy and autonomy, the resurgence of tuberculosis has sparked new and troublesome concerns. One particularly intense controversy has emerged around the value and appropriateness of single disease hospitals. In HIV disease, the single hospital turns out to be an altogether unsuitable and unnecessary innovation. In the instance of tuberculosis, however, it appears to have a critical (...) and legitimate role, particularly for involuntary commitment of patients who have been non-compliant with treatment regimens. To be sure, that role must be carefully circumscribed and the facilities themselves closely monitored. But a hospital dedicated to tuberculosis now occupies a central place in public policy that is not to be found for HIV disease. What considerations promote this difference, and how a single disease hospital for tuberculosis may avoid the pitfalls that make it so inapposite for HIV, are the two questions this essay will be exploring. (shrink)

Roots presents articles on major discoveries that laid the basis for contemporary molecular and cellular biology. In this article, Norton D. Zinder reviews the first findings about the single‐stranded DNA‐containing bacteriophages and what is known today about the genetics and molecular biology of these phages.

In this paper, we propose a new concept named the uniform single valued neutrosophic graph. An illustrative example and some properties are examined. Next, we develop an algorithmic approach for computing the complement of the single valued neutrosophic graph. A numerical example is demonstrated for computing the complement of single valued neutrosophic graphs and uniform single valued neutrosophic graph.

The crucial phase of speciation is argued to be the evolution of mating cross-incompatibility (prezygotic incompatibility) between the genotypes distinguishing the prospective species populations. Based on this idea, a single-locus model of speciation is presented, which is shown to be biologically plausible and may help to settle the controversy as to the biological significance of single-locus modes of speciation. The model involves three alleles, two of which characterize in homozygous state the prospective species populations and in heterozygous state their hybrids. (...) The third allele represents a mutant which is equivalent to one of the first two alleles with the exception that it inhibits mating with carriers of the third allele. This third allele is fixed in one population and immigrates into a second population which contains the mutant inhibiting matings with members of the former population. Migration in the reverse direction does not occur. Proceeding from a widely applicable concept of fitness and mating preference it is shown that postzygotic incompatibility (hybrid or heterozygote disadvantage) alone suffices to trigger evolutionary replacement of the extant mating relations in the population receiving immigrants by any arbitrary degree of prezygotic incompatibility. This corroborates Wallace's hypothesis and emphasizes the potential biological relevance of speciation by reinforcement (parapatric speciation) at single gene loci. (shrink)

This work introduces the framework for selecting architecture in 5G networks, considering various technological, performance, economic, and operational factors. With the emergence of 5G technology, the architecture selection process has become pivotal in meeting diverse requirements for ultra-high-speed connectivity, low latency, scalability, and diverse service demands. The evaluation comprehensively analyses different architecture options, including centralized, distributed, cloud-based, and virtualized architectures. Factors such as network performance, scalability, cost-effectiveness, security, and compatibility are considered within a multi-criteria decision-making framework. Findings reveal each architecture (...) option's diverse strengths and limitations, emphasizing the importance of aligning architectural choices with specific use cases, deployment scenarios, and business objectives. We used the concept of multi-criteria decision-making (MCDM) methodology to control the various criteria. We used the single-valued neutrosophic set (SVNS) to deal with vague and inconsistent data. The SVNS is integrated with the hyperSoft set. The proposed methodology uses a single-valued neutrosophic hyperSoft set (SVNHSS) to select the best 5G architecture. We used the VIKOR method as an MCDM method to rank the alternatives. The proposed framework provides stakeholders with a structured methodology to evaluate and prioritize architecture options, facilitating informed decision-making in the complex landscape of 5G network deployments. (shrink)

Single‐cell microinjection has been successfully used to deliver exogenous proteins, cDNA constructs, peptides, drugs and particles into transfection‐challenged cells. With precisely controlled delivery dosage and timing, microinjection has been used in many studies of primary cultured cells, transgenic animal production, in vitro fertilization and RNA inference. This review discusses the advantages and limits of microinjection as a mechanical delivery method and its applications to attached and suspended cells. BioEssays 30:606–610, 2008. © 2008 Wiley Periodicals, Inc.

Services for single parents constitute a category of child and family services. These services are carried out by public and non-governmental bodies for people who are single parents by the unfortunate events or by their own choice. Individuals come to single parenthood mainly through divorce, separation, birth outside of marriage, child abuse/neglect, death of a partner/widowhood, and adoption.

Logothetis, N.K.: Single units and conscious vision. Philosophical Transactions of the Royal Society of London Series B-Biological Sciences 353, 1801-1818 (1998) Abstract.

In this paper, we introduce the notion of single-valued neutrosophic soft uniform spaces as a view point of the entourage approach. We investigate the relationship among single-valued neutrosophic soft uniformities, single-valued neutrosophic soft topologies and single-valued neutrosophic soft interior operators. Also, we study several single-valued neutrosophic soft topologies induced by a single-valued neutrosophic soft uniform space.

A fundamental fact about human minds is that they are never truly alone: all minds are steeped in situated interaction. That social interaction matters is recognized by any experimentalist who seeks to exclude its influence by studying individuals in isolation. On this view, interaction complicates cognition. Here, we explore the more radical stance that interaction co-constitutes cognition: that we benefit from looking beyond single minds toward cognition as a process involving interacting minds. All around the cognitive sciences, there are approaches (...) that put interaction center stage. Their diverse and pluralistic origins may obscure the fact that collectively, they harbor insights and methods that can respecify foundational assumptions and fuel novel interdisciplinary work. What might the cognitive sciences gain from stronger interactional foundations? This represents, we believe, one of the key questions for the future. Writing as a transdisciplinary collective assembled from across the classic cognitive science hexagon and beyond, we highlight the opportunity for a figure-ground reversal that puts interaction at the heart of cognition. The interactive stance is a way of seeing that deserves to be a key part of the conceptual toolkit of cognitive scientists. (shrink)

It is tempting to think that multi premise closure creates a special class of paradoxes having to do with the accumulation of risks, and that these paradoxes could be escaped by rejecting the principle, while still retaining single premise closure. I argue that single premise deduction is also susceptible to risks. I show that what I take to be the strongest argument for rejecting multi premise closure is also an argument for rejecting single premise closure. Because of the symmetry between (...) the principles, they come as a package: either both will have to be rejected or both will have to be revised. (shrink)

What happens to the "conversational score" when speakers in a conversation push the score for a context-sensitive term in different directions? In epistemology, contextualists are often construed as holding that both the skeptic ("You don't know!") and her opponent ("Oh, yes I do!") speak truthfully when they debate. This assumes a "multiple scoreboards" version of contextualism. But contextualists themselves typically opt for "single scoreboard" views on which such apparently competing claims really do conflict. This paper explores several single scoreboard options (...) for contextualists, opting in the end for the "gap view," on which neither of our debaters speaks truthfully. (shrink)

Among the possible solutions to the paradoxes of collective preferences, single-peakedness is significant because it has been associated to a suggestive conceptual interpretation: a single-peaked preference profile entails that, although individuals may disagree on which option is the best, they conceptualize the choice along a shared unique dimension, i.e. they agree on the rationale of the collective decision. In this article, we discuss the relationship between the structural property of singlepeakedness and its suggested interpretation as uni-dimensionality of a social choice. (...) In particular, we offer a formalization of the relationship between single-peakedness and its conceptual counterpart, we discuss their logical relations, and we question whether single-peakedness provides a rationale for collective choices. (shrink)

Electronic institutional review board systems (eIRBs) have become an integral component in ensuring compliance with Human Research Protection Program (HRPP) and IRB requirements. Despite this, few of these systems are configured to administer the single IRB (sIRB) process mandated by the National Institutes of Health (NIH) for multisite research. We interviewed 103 sIRB administrators, chairs, members, and staff members about their experiences with sIRB multisite research review. We observed three main obstacles to adapting existing eIRB systems to accommodate the sIRB (...) process: (1) Existing systems are not designed for sIRBs and are not configured to administer sIRB responsibilities, (2) they are not interoperable, and (3) resources to improve existing systems are lacking. Our findings suggest that IRBs that act as an sIRB will need major changes to their electronic systems in order to accommodate sIRB processes. These difficulties threaten both the ability of IRBs to focus on ethical rather than bureaucratic problems and the efficiency of multisite trials. (shrink)

In this paper, we define the regular and totally regular single valued neutrosophic hypergraphs, and discuss the order and size along with properties of regular and totally regular single valued neutrosophic hypergraphs. We also extend work on completeness of single valued neutrosophic hypergraphs.

SINGLE MAGNETIC NORTHPOLES AND SOUTPOLESAND THEIR IMPORTANCE FOR SCIENCETen lectures delivered at the University of Viennaduring the summer semester of 1947byDr. Felix EhrenhaftU. S. Visiting Profe...

Replication protein A (RPA), the major single‐stranded DNA‐binding protein in eukaryotic cells, is required for processing of single‐stranded DNA (ssDNA) intermediates found in replication, repair, and recombination. Recent studies have shown that RPA binding to ssDNA is highly dynamic and that more than high‐affinity binding is needed for function. Analysis of DNA binding mutants identified forms of RPA with reduced affinity for ssDNA that are fully active, and other mutants with higher affinity that are inactive. Single molecule studies showed that (...) while RPA binds ssDNA with high affinity, the RPA complex can rapidly diffuse along ssDNA and be displaced by other proteins that act on ssDNA. Finally, dynamic DNA binding allows RPA to prevent error‐prone repair of double‐stranded breaks and promote error‐free repair. Together, these findings suggest a new paradigm where RPA acts as a first responder at sites with ssDNA, thereby actively coordinating DNA repair and DNA synthesis. (shrink)

Do children’s single words related to motion and change also encode aspects of environmental events highlighted by Talmy’s motion event analysis? If so, these meanings may predict children’s early verb meanings. Analyzing the kinds of meanings expressed in single “dynamic event words” through motion event semantics yields links between early true verbs in sentences and the semantics encoded in these single words. Dynamic event words reflect the sense of temporal and spatial reversibility established in the late sensorimotor period. We propose (...) that these dynamic meanings provide the semantic foundation for the most common verbs included in early sentences, and thus a bootstrap to full development of the verb repertoire. In this study, we followed the spoken language development of five children. We identified dynamic event words as encoding dynamic change in the following dimensions: spatial direction in relation to self; vertical spatial direction; figure/ground relationships; and temporal event sequences. Verbs continuing the semantics previously identified in dynamic event words occurred early and dominated the verb repertoire through 24 months of age. (shrink)

Arrow's account (1951/1963) of the problem of social choice is based upon the assumption that the preferences of each individual in the relevant group are expressible by a single ordering. This paper lifts that assumption and develops a multidimensional generalization of Arrow's framework. I show that, like Arrow's original framework, the multidimensional generalization is affected by an impossibility theorem, highlighting not only the threat of dictatorship of a single individual, but also the threat of dominance of a single dimension. In (...) particular, even if preferences are single-peaked across individuals within each dimension – a situation called intradimensional single-peakedness – any aggregation procedure satisfying Arrow-type conditions will make one dimension dominant. I introduce lexicographic hierarchies of dimensions as a class of possible aggregation procedures under intradimensional single-peakedness. The interpretation of the results is discussed. (shrink)

Many theories about human number representation stress the importance of a central semantic representation that includes the magnitude information of small integer numbers, and that is conceived as an abstract, compressed number line. However, thus far there has been little or no direct evidence that units and teens are represented on the same number line. In two masked priming experiments, we show that single-digit and two-digit Arabic numerals are equally well primed by an Arabic numeral with the same number of (...) digits as by an equally distant Arabic numeral with a different number of digits (e.g. the priming effect of 7 on the target 9 is the same as the priming effect of 11 on the target 9). The finding was obtained both with a number naming task and with a parity judgement task. This is in line with the hypothesis that units and teens are part of a continuous number line. (shrink)

A recent single cell mRNA sequencing study by Dueck et al. compares neuronal transcriptomes to the transcriptomes of adipocytes and cardiomyocytes. Single cell ‘omic approaches such as those used by the authors are at the leading edge of molecular and biophysical measurement. Many groups are currently employing single cell sequencing approaches to understand cellular heterogeneity in cancer and during normal development. These single cell approaches also are beginning to address long‐standing questions regarding nervous system diversity. Beyond an innate interest in (...) cataloging cell type diversity in the brain, single cell neuronal diversity has important implications for neurotypic neural circuit function and for neurological disease. Herein, we review the authors’ methods and findings, which most notably include evidence of unique expression profiles in some single neurons. (shrink)

This book provides an account of discursive or reason-governed cognition, by synthesizing research in the philosophy of language, the philosophy of mind, and evolutionary anthropology. -/- Using the grasp of a natural language as a model for the autonomous or self-governed rationality of discursive cognition, the author uses a semantics for individual intentions, shared intentions, and normative attitudes as a framework for understanding what it is to be a rational animal. This semantics interprets claims about shared intentions and claims about (...) what people ought and may do as the expression of plans of action that involve taking the points of view of other people within a community. This has important consequences for our understanding of both the natural basis and the social relevance of intentional and normative mental states. In order to distinguish the strong and weak modal force, which characterizes normativity but not shared intentionality, the author argues that a notion of single-minded practical cognition is necessary. This account of single-mindedness is then used to shed light on the autonomy or self-government characteristic of discursive cognition, as manifest in a linguistic community whose members are able to adopt the standpoints of others. -/- Drawing together research in philosophy and the related sciences, the formal account of the semantic content of the claims we use to give expression to shared intentional and normative mental states integrates well with research in cognitive science, evolutionary anthropology, and social psychology concerning the ontogenetic and phylogenetic development of shared intentionality and norm psychology in human beings and other primates. The Single-Minded Animal will appeal to researchers and advanced students working on shared intentionality, normativity, rationality, cognitive science, social and developmental psychology, and evolutionary anthropology. (shrink)

In this paper, I will defend a new compositional semantics for single-domain free logic. This semantics makes use of a distinction between the semantic value of a singular term and its semantic referent. The semantic value of a singular term is conceived of as a set that either contains the semantic referent or no element at all. The semantic referent is the object that the term designates. Before I will introduce this new semantics for single-domain predicate and an S5-type modal (...) logic in detail, I will present five related problems of compositionality of the standard semantics for these logical systems. After that I will show in detail how my new proposed alternative semantics can be used to solve nearly all of the outlined five problems. (shrink)

Frauchiger and Renner have recently claimed to prove that “Single-world interpretations of quantum theory cannot be self-consistent”. This is contradicted by a construction due to Bell, inspired by Bohmian mechanics, which shows that any quantum system can be modelled in such a way that there is only one “world” at any time, but the predictions of quantum theory are reproduced. This Bell–Bohmian theory is applied to the experiment proposed by Frauchiger and Renner, and their argument is critically examined. It is (...) concluded that it is their version of “standard quantum theory”, incorporating state vector collapse upon measurement, that is not self-consistent. (shrink)

A quasivariety of algebras has the joint embedding property (JEP) if and only if it is generated by a single algebra A. It is structurally complete if and only if the free ℵ0‐generated algebra in can serve as A. A consequence of this demand, called ‘passive structural completeness’ (PSC), is that the nontrivial members of all satisfy the same existential positive sentences. We prove that if is PSC then it still has the JEP, and if it has the JEP and (...) its nontrivial members lack trivial subalgebras, then its relatively simple members all belong to the universal class generated by one of them. Under these conditions, if is relatively semisimple then it is generated by one ‐simple algebra. We also prove that a quasivariety of finite type, with a finite nontrivial member, is PSC if and only if its nontrivial members have a common retract. The theory is then applied to the variety of De Morgan monoids, where we isolate the sub(quasi)varieties that are PSC and those that have the JEP, while throwing fresh light on those that are structurally complete. The results illuminate the extension lattices of intuitionistic and relevance logics. (shrink)