I distinguish between ‘substantival’ and ‘functional’ forms of vitalism in the eighteenth century. Substantival vitalism presupposes the existence of a (substantive) vital force which either plays a causal role in the natural world as studied scientifically, or remains an immaterial, extra-causal entity. Functional vitalism tends to operate ‘post facto’, from the existence of living bodies to the search for explanatory models that will account for their uniquely ‘vital’ properties better than fully mechanistic models can. I discuss representative figures of the (...) Montpellier school (Bordeu, Ménuret, Fouquet) as functional rather than substantival vitalists, and suggest an additional point regarding the reprisal of vitalism(s) in the 20th century, from Driesch to Canguilhem: that in addition to the substantival and functional varieties, we encounter a third species of vitalism, which I term ‘attitudinal’, as it argues for vitalism as a kind of attitude. (shrink)

The species of vitalism discussed here is a malleable construct, often with a poisonous reputation (but one which I want to rehabilitate), hovering in between the realms of the philosophy of biology, the history of medicine, and the scientific background of the Radical Enlightenment (case in point, the influence of vitalist medicine on Diderot). This is a more vital vitalism, or at least a more ‘biologistic,’ ‘embodied,’ medicalized vitalism. I distinguish between what I would call ‘substantival’ and ‘functional’ forms (...) of vitalism, as applied to the eighteenth century. Substantival vitalism presupposes the existence of something like a (substantive) vital force which either plays a causal role in the natural world as studied by scientific means, or remains a kind of hovering, extra-causal entity. Functional vitalism tends to operate “post facto,” from the existence of living bodies to the desire to find explanatory models that will do justice to their uniquely ‘vital’ properties in a way that fully mechanistic models (such as Cartesian mechanism) cannot. I discuss some representative figures of the Montpellier school as being functional rather than substantival vitalists, particularly as regards the models of organic organization which they develop, and make some suggestions as to how these relate to the then-nascent science of biology. (shrink)

Developmental biology has resurfaced in recent years, often without a clearly central role for the organism. The organism is pulled in divergent directions: on the one hand, there is an important body of work that emphasizes the role of the gene in development, as executing and controlling embryological change; on the other hand, there are more theoretical approaches under which the organism disappears as little more than an instance for testing biological generalizations. I press here for the ineliminability of the (...) organism in developmental biology on explanatory grounds. I examine classical work concerned with growth and development, particularly in Drosophila and C. elegans. Some of this work is suggestive of modular development, and accordingly suggests a level below that of the organism as being explanatory. These are not the only type of case. There are other equally well-established results, which indicate greater integration in the developing organism. Though with a modular organization the organism can be thought of as made up of its constituent traits, and though the explanations of these traits may lie in terms of cells or genes, even with modular development the explanations of "genetic" differences require an appeal to the organism. With non-modular organization the organism has an even more central role. This does not mean that these genetic or cellular contributions are unreal in any way, or that development requires some sort of vitalistic contribution; but the genetic contributions make sense only as constituents of the organism, embedded in a larger organic context. (shrink)

This book offers a comprehensive account of vitalism and the Romantic philosophy of nature. The author explores the rise of biology as a unified science in Germany by reconstructing the history of the notion of “vital force,” starting from the mid-eighteenth through the early nineteenth century. Further, he argues that Romantic Naturphilosophie played a crucial role in the rise of biology in Germany, especially thanks to its treatment of teleology. In fact, both post-Kantian philosophers and naturalists were guided by teleological (...) principles in defining the object of biological research. The book begins by considering the problem of generation, focusing on the debate over the notion of “formative force.” Readers are invited to engage with the epistemological status of this formative force, i.e. the question of the principle behind organization. The second chapter provides a reconstruction of the physiology of vital forces as it was elaborated in the mid- to late-eighteenth century by the group of physicians and naturalists known as the “Göttingen School.” Readers are shown how these authors developed an understanding of the animal kingdom as a graded series of organisms with increasing functional complexity. Chapter three tracks the development of such framework in Romantic Naturphilosophie. The author introduces the reader to the problem of classification, showing how Romantic philosophers of nature regarded classification as articulated by a unified plan that connects all living forms with one another, relying on the idea of living nature as a universal organism. In the closing chapter, this analysis shows how the three instances of pre-biological discourse on living beings – theory of generation, physiology and natural history – converged to form the consolidated disciplinary matrix of a general biology. The book offers an insightful read for all scholars interested in classical German philosophy, especially those researching the philosophy of nature, as well as the history and philosophy of biology. (shrink)

Philosophy of biology before biology -/- Edited by Cécilia Bognon-Küss & Charles T. Wolfe -/- Table of contents -/- Cécilia Bognon-Küss & Charles T. Wolfe. Introduction -/- 1. Cécilia Bognon-Küss & Charles T. Wolfe. The idea of “philosophy of biology before biology”: a methodological provocation -/- Part I. FORM AND DEVELOPMENT -/- 2. Stéphane Schmitt. Buffon’s theories of generation and the changing dialectics of molds and molecules 3. Phillip Sloan. Metaphysics and “Vital” Materialism: The Gabrielle Du Châtelet Circle and French (...) Vitalism 4. John Zammito. The Philosophical Reception of C. F. Wolff’s Epigenesis in Germany, 1770-1790: Herder, Tetens and Kant -/- Part II. ORGANISM & ORGANIZATION 5. François Duchesneau. Senebier and the Advent of General Physiology 6. Tobias Cheung. Organization and Process. Living Systems Between Inner and Outer Worlds: Cuvier, Hufeland, Cabanis. -/- Part III. SYSTEMS 7. Georg Toepfer. Philosophy of Ecology Long Before Ecology: Kant’s Idea of an Organized System of Organized Beings 8. Ina Goy. "All is leaf". Goethe's plant philosophy and poetry 9. Snait Gissis. ‘Biology’, Lamarck, Lamarckisms -/- POSTSCRIPTS 1. Lynn Nyhart. A Historical Proposal Around Prepositions -/- 2. Philippe Huneman. Philosophy after Philosophy of Biology before Biology -/- Cécilia Bognon-Küss and Charles T. Wolfe. Conclusion . (shrink)

Well prior to the invention of the term ‘biology’ in the early 1800s by Lamarck and Treviranus (and lesser-known figures in the decades prior), and also prior to the appearance of terms such as ‘organism’ under the pen of Leibniz and Stahl in the early 1700s, the question of ‘Life’, that is, the status of living organisms within the broader physico-mechanical universe, agitated different corners of the European intellectual scene. From modern Epicureanism to medical Newtonianism, from Stahlian animism to the (...) discourse on the ‘animal economy’ in vitalist medicine, models of living being were constructed in opposition to ‘merely anatomical’, structural, mechanical models. It is therefore striking that the classic narratives of the Scientific Revolution conspicuously avoid any consideration of what status to grant living beings in a newly physicalized universe (I discuss this in Wolfe 2011, 2019 chapt. 1). Neither Harvey, nor Boyle, nor Locke (to name some likely candidates, the latter having studied with Willis and collaborated with Sydenham) ever ask what makes organisms unique, or conversely, what does not. In this chapter I seek to establish how something we might call ‘the knowledge of Life’, to use an expression of Georges Canguilhem’s, emerged as part of early modernity without being part of the mainstream history of life science. This leads to the question, can one can correlate early modern “knowledge of life” with the emergence of a science called ‘biology’? (see Zammito 2018, Wolfe 2019, Bognon-Küss and Wolfe eds. 2019). It was once fashionable to speak of, e.g. ‘precursors of Darwin’, and then Canguilhem and Foucault famously did away with the category of precursor. But how then do we account for the phase that precedes the constitution of a science? With the case of biology, how do we account for the increasing fascination with the ontology of Life during the decades prior to the ‘naming of biology’, as McLaughlin has called it, at the end of the eighteenth century? This increased focus on Life and the ontology of Life sits awkwardly, both with mainstream narratives of the Scientific Revolution and of the history of biology. In seeking to address this increased focus (in which vitalism plays a role but was by no means the only conceptual actor: Wolfe 2020), I critically examine Foucault’s notorious claim (Foucault 1966) that there was no such thing as ‘Life’ in the eighteenth century and thus no such thing as biology. (shrink)

my introduction to special issue of Science in Context on 18c vitalism.

Vitalism is understood as impacting the history of the life sciences, medicine and philosophy, representing an epistemological challenge to the dominance of mechanism over the last 200 years, and partly revived with organicism in early theoretical biology. The contributions in this volume portray the history of vitalism from the end of the Enlightenment to the modern day, suggesting some reassessment of what it means both historically and conceptually. As such it includes a wide range of material, employing both historical (...) and philosophical methodologies, and it is divided fairly evenly between 19th and 20th century historical treatments and more contemporary analysis. This volume presents a significant contribution to the current literature in the history and philosophy of science and the history of medicine. (shrink)

In this essay I seek to critically evaluate some forms of holism and organicism in biological thought, as a more deflationary echo to Gilbert and Sarkar's reflection on the need for an 'umbrella' concept to convey the new vitality of holistic concepts in biology (Gilbert and Sarkar 2000). Given that some recent discussions in theoretical biology call for an organism concept (from Moreno and Mossio’s work on organization to Kirschner et al.’s research paper in Cell, 2000, building on chemistry to (...) articulate what they called “molecular vitalism,” studying the “vitalistic” properties of molecular, cellular, and organismal function, and Pepper and Herron’s suggestion in their 2008 paper that organisms define a category that evolutionary biology cannot do without), the question, what concept of organicism are they calling for? To what extent are such claims philosophically committed to a non-naturalistic concept of organism as organizing centre, as a foundational rather than heuristic concept – or possibly a “biochauvinism,” to use Di Paolo’s term (Di Paolo 2009)? My aim in this paper is to conceptually clarify the forms of holism and organicism that are involved in these cases (and I acknowledge that the study of early 20th-century holisms [Peterson 2010] indicates that not all of them were in fact ‘organicist’ or ‘biologistic’). I suggest that contemporary holists are still potentially beholden to a certain kind of vitalism or “biochauvinism”; but that when they reduce their claims to mere heuristics, conversely, they risk losing sight of a certain kind of organizational “thickness”, a “vital materiality” (Wheeler 2010) which is characteristic of biological systems (Bechtel 2007). And I ask if it is possible to articulate a concept of biological holism or organicism which is neither an empirical ‘biochauvinism’ nor a metaphysical ‘vitalism’? (shrink)

This article proposes an empirical approach to understanding the life of an organism that overcomes reductionist and dualist approaches. The approach is based on Immanuel Kant’s analysis of the cognitive conditions required for the recognition of an organism: the concept of teleology and the assumption of a formative power of self-generation. It is analyzed how these two criteria are applied in the cognition of a developing organism. Using the example of a developmental series of a plant leaf, an active and (...) relational process between observer and developing organism is shown, within which the teleology and self-generating power of the organism can be empirically observed through the mental faculties of understanding and will. Furthermore, it is emphasized that, according to Kant, even physical objects are not readily given, but are actively constituted through the unification of sense perceptions with concepts. This Kantian mode of objectification facilitates cognition of the physical properties of an organism. It can be supplemented with a participatory and co-constitutive mode of realization, in which the life of the organism (its teleologically organizing and self-generating power) can become an object of empirical research. Furthermore, it is argued that the participatory mode also facilitates an expanded conception of nature that allows for the existence of living beings within it. Finally, an analogy to Goethe’s approach to the living organism is highlighted. In summary, it is stated that to understand life, one must consciously participate in it. (shrink)

Following the revival in the last decades of the concept of “organism”, scholarly literature in philosophy of science has shown growing historical interest in the theory of Immanuel Kant, one of the “fathers” of the concept of self-organisation. Yet some recent theoretical developments suggest that self-organisation alone cannot fully account for the all-important dimension of autonomy of the living. Autonomy appears to also have a genuine “interactive” dimension, which concerns the organism’s functional interactions with the environment and does not simply (...) derive from its internal organisation. Against this background, we focus on a family of natural philosophical approaches that historically have already strongly taken in account this aspect of autonomy, notably going beyond Kant’s perspective on self-organisation. We thus review Hegel, Plessner, and Jonas’ different perspectives on living beings, focussing in particular on four points: the distinction between organic and inorganic, the theory of biological organisation, the processuality of the living, and the “boundary” between inside and outside, through which the organism establishes its relationship to the environment. We, then, compare the three perspectives on these four points, and finally address the question of what advantages their contribution present—especially compared to Kant’s theory—with respect to the topic of organism’s autonomy. This could help—we hope—to better understand what is at the stake still today. (shrink)

The idea of a self-organized system brings both political and biological discourses together, for they both aim at explaining how a certain compound can achieve self-unity out of plurality. Whereas biological metaphors in politics have been much examined, political metaphors in biology have not. In this paper I intend to show how political metaphors can enlighten biological discourses, taking the work of Aristotle as a case-study. The relationship between the main elements of a living-body could be better understood within a (...) political scheme: the soul rules over the body through pneuma, its prime minister. This scheme entails, thus, to re-examine Aristotle’s definition of soul in the light of the key concept of pneuma, and to replace the hylemorphic explanation with a triadic one. On the one hand, soul is the entelecheia of the body as it keeps both the form and the end of the organism, which is its unity. On the other hand, the moving-efficacious principle that performs unity by circulating through the body, and by linking the body to its environment is pneuma. Therefore, the political formula: “the king does not govern” could shed light upon the structure of the living body: whereas the soul rules the body, pneuma governs it. Although Aristotle does not build his biology upon political concepts, metaphors are already there, shaping his explanations, within the bio-theo-political paradigm of autarchy. (shrink)

In recent decades, several theories have claimed to explain the teleological causality of organisms as a function of self-organising and self-producing processes. The most widely cited theories of this sort are variations of autopoiesis, originally introduced by Maturana and Varela. More recent modifications of autopoietic theory have focused on system organisation, closure of constraints and autonomy to account for organism teleology. This article argues that the treatment of teleology in autopoiesis and other organisation theories is inconclusive for three reasons: First, (...) non-living self-organising processes like autocatalysis meet the defining features of autopoiesis without being teleological; second, organisational approaches, whether defined in terms of the closure of constraints, self-determination or autonomy, are unable to specify teleological normativity, that is, the individuation of an ultimate beneficiary; third, all self-organised systems produce local order by maximising the throughput of energy and/or material (obeying the maximum entropy production (MEP) principle) and thereby are specifically organised to undermine their own critical boundary conditions. Despite these inadequacies, an alternative approach called teleodynamics accounts for teleology. This theory shows how multiple self-organising processes can be collectively linked so that they counter each other’s MEP principle tendencies to become codependent. Teleodynamics embraces – not ignoring – the difficulties of self-organisation, but reinstates teleology as a radical phase transition distinguishing systems embodying an orientation towards their own beneficial ends from those that lack normative character. (shrink)

Rosen accuses conventional biology of abandoning its main challenge: the understanding of the nature of life. Biologists generally act subservient to physicists, handicapped by the Cartesian metaphor of the organism as machine. This allows biologists to eschew the issue of intentionality and finalism. The machine metaphor assures biologists that they do not need to appeal to laws other than the ones used by physicists. Rosen argues that the machine metaphor affords the reduction of the organism to its constituent parts.

The organism is neither a discovery like the circulation of the blood or the glycogenic function of the liver, nor a particular biological theory like epigenesis or preformationism. It is rather a concept which plays a series of roles – sometimes overt, sometimes masked – throughout the history of biology, and frequently in very normative ways, also shifting between the biological and the social. Indeed, it has often been presented as a key-concept in life science and the ‘theorization’ of Life, (...) but conversely has also been the target of influential rejections: as just an instrument of transmission for the selfish gene, but also, historiographically, as part of an outdated ‘vitalism’. Indeed, the organism, perhaps because it is experientially closer to the ‘body’ than to the ‘molecule’, is often the object of quasi-affective theoretical investments presenting it as essential, sometimes even as the pivot of a science or a particular approach to nature, while other approaches reject or attack it with equal force, assimilating it to a mysterious ‘vitalist’ ontology of extra-causal forces, or other pseudo-scientific doctrines. This paper does not seek to adjudicate between these debates, either in terms of scientific validity or historical coherence; nor does it return to the well-studied issue of the organism-mechanism tension in biology. Recent scholarship has begun to focus on the emergence and transformation of the concept of organism, but has not emphasized so much the way in which organism is a shifting, ‘go-between’ concept – invoked as ‘natural’ by some thinkers to justify their metaphysics, but then presented as value-laden by others, over and against the natural world. The organism as go-between concept is also a hybrid, a boundary concept or an epistemic limit case, all of which partly overlap with the idea of ‘nomadic concepts’. Thereby the concept of organism continues to function in different contexts – as a heuristic, an explanatory challenge, a model of order, of regulation, etc. – despite having frequently been pronounced irrelevant and reduced to molecules or genes. Yet this perpetuation is far removed from any ‘metaphysics of organism’, or organismic biology. (shrink)

In this thesis, I discuss the organism's self-organization from the perspective of relational ontology. I critically examine scientific and philosophical sources that appeal to the concept of self-organization. By doing this, I aim to carry out a thorough investigation into the underlying reasons of emergent order within the ontogeny of the organism. Moreover, I focus on the relation between universal dynamics of organization and the organization of living systems. I provide a historical review of the development of modern ideas related (...) to self-organization. These ideas have been developed in relation to various research areas including thermodynamics, molecular biology, developmental biology, systems theory, and so on. In order to develop a systematic understanding of the concept, I propose a conceptual distinction between transitional self-organization and regulative self-organization. The former refers to the spontaneous emergence of order, whereas the latter refers to the self-maintaining characteristic of the living systems. I show the relation between these two types of organization within biological processes. I offer a critical analysis of various theories within the organizational approach. Several ideas and notions in these theories originate from the early studies in cybernetics. More recently, autopoiesis and the theory of biological autonomy asserted certain claims that were critical toward the ideas related to self-organization. I advocate a general theory of self-organization against these criticisms. I also examine the hierarchical nature of the organism's organization, as this is essential to understand regulative self-organization. I consider the reciprocal relation between bottom-up and top-down dynamics of organization as the basis of the organism's individuation. To prove this idea, I appeal to biological research on molecular self-assembly, pattern formation (including reaction-diffusion systems), and the self-organized characteristic of the immune system. Finally, I promote the idea of diachronic emergence by drawing support from biological self-organization. I discuss the ideas related to constraints, potentiality, and dynamic form in an attempt to reveal the emergent nature of the organism. To demonstrate the dynamicity of form, I examine research into biological oscillators. I draw the following conclusions: synchronic condition of the organism is irreducibly processual and relational, and this is the basis of the organism's potentiality for various organizational states. (shrink)

Sensibility, in any of its myriad realms – moral, physical, aesthetic, medical and so on – seems to be a paramount case of a higher-level, intentional property, not a basic property. Diderot famously made the bold and attributive move of postulating that matter itself senses, or that sensibility (perhaps better translated ‘sensitivity’ here) is a general or universal property of matter, even if he at times took a step back from this claim and called it a “supposition.” Crucially, sensibility is (...) here playing the role of a ‘booster’: it enables materialism to provide a full and rich account of the phenomena of conscious, sentient life, contrary to what its opponents hold: for if matter can sense, and sensibility is not a merely mechanical process, then the loftiest cognitive plateaus are accessible to materialist analysis, or at least belong to one and the same world as the rest of matter. This was noted by the astute anti-materialist critic, the Abbé Lelarge de Lignac, who, in his 1751 Lettres à un Amériquain, criticized Buffon for “granting to the body [la machine, a common term for the body at the time] a quality which is essential to minds, namely sensibility.” This view, here attributed to Buffon and definitely held by Diderot, was comparatively rare. If we look for the sources of this concept, the most notable ones are physiological and medical treatises by prominent figures such as Robert Whytt, Albrecht von Haller and the Montpellier vitalist Théophile de Bordeu. We then have, or so I shall try to sketch out, an intellectual landscape in which new – or newly articulated – properties such as irritability and sensibility are presented either as an experimental property of muscle fibers, that can be understood mechanistically (Hallerian irritability, as studied recently by Hubert Steinke and Dominique Boury) or a property of matter itself (whether specifically living matter as in Bordeu and his fellow montpelliérains Ménuret and Fouquet, or matter in general, as in Diderot). I am by no means convinced that it is one and the same ‘sensibility’ that is at issue in debates between these figures (as when Bordeu attacks Haller’s distinction between irritability and sensibility and claims that ‘his own’ property of sensibility is both more correct and more fundamental in organic beings), but I am interested in mapping out a topography of the problem of sensibility as property of matter or as vital force in mid-eighteenth-century debates – not an exhaustive cartography of all possible positions or theories, but an attempt to understand the ‘triangulation’ of three views: a vitalist view in which sensibility is fundamental, matching up with a conception of the organism as the sum of parts conceived as little lives (Bordeu et al.); a mechanist, or ‘enhanced mechanist’ view in which one can work upwards, step by step from the basic property of irritability to the higher-level property of sensibility (Haller); and, more eclectic, a materialist view which seeks to combine the mechanistic, componential rigour and explanatory power of the Hallerian approach, with the monistic and metaphysically explosive potential of the vitalist approach (Diderot). It is my hope that examining Diderot in the context of this triangulated topography of sensibility as property sheds light on his famous proclamation regarding sensibility as a universal property of matter. (shrink)

This paper investigates Hegel’s account of the animal organism as it is presented in the Philosophy of Nature, with a special focus on its normative implications. I argue that the notion of “organisation” is fundamental to Hegel’s theory of animal normativity. The paper starts by showing how a Hegelian approach takes up the scientific image of organism and assigns a basic explanatory role to the notion of “organisation” in its understanding living beings. Moving from this premise, the paper turns to (...) the group of accounts in contemporary theoretical biology known as “organisational accounts”, which offer a widely debated strategy for naturalizing teleology and normativity in organisms. As recent scholarship recognizes, these accounts explicitly rely on insights from Kant and Post-Kantianism. I make the historical and conceptual argument that Hegel’s view of the organism shares several basic commitments with OAs, especially regarding the notion of “organisational closure”. I assess the account of normativity that such accounts advance and its implications for how we approach Hegel. Finally, I argue that the notion of “organisation” is more fundamental to Hegel’s theory of animal normativity than the Aristotelian notion of “Gattung” or “species”, which by contrast appears derivative – at least in the Philosophy of Nature and the Lectures – and does not play the central role in his account maintained by some scholars. (shrink)

In earlier work I wrestled with the question of the “ontological status” of organisms. It proved difficult to come to a clear decision, because there are many candidates for what such a status is or would be and of course many definitions of what organisms are. But what happens when we turn to theoretical projects “about” organisms that fall under the heading “organicist”? I first suggest that organicist projects have a problem: a combination of invoking Kant, or at least a (...) Kantian “regulative ideal,” usually presented as the epistemological component (or alternately, the complete overall vision) of a vision of organism – as instantiating natural purposes, as a type of “wholeWhole, wholes” distinct from a merely mechanistically specifiable set of parts, etc. – and a more ontological statement about the inherent or essential features of organisms, typically presented according to a combination of a “list of heroes” or “laundry list” of properties of organisms. This amounts to a category mistake. Other problems concern the too-strict oppositions between mechanism and organi(ci)sm, and symmetrical tendencies to “ontologize” (thus objectifying) properties of organisms and to “subjectify” them (turning them into philosophies of subjectivity). I don’t mean to suggest that no one should be an organicist or that Kant is a name that should be banished from civilized society. Rather, to borrow awkwardly from Sade, “organicists, one more effort!” if one wants a naturalistic, non-foundationalist concept of organicism, which is indeed quite active in recent theoretical biology, and which arguably was already alive in the organismic and even vitalist theories of thinkers like Goldstein and Canguilhem. (shrink)

Explanations in behavioural neuroscience are often said to be mechanistic in the sense that they explain an organism’s behaviour by describing the activities and organisation of the organism’s parts that are “constitutively relevant” to organism behaviour. Much has been said about the constitutive relevance of working parts (in debates about the so-called “mutual manipulability criterion”), but relatively little has been said about the constitutive relevance of the organising relations between working parts. Some New Mechanists seem to endorse a simple causal-linking (...) account: organising relations are constitutively relevant to organism behaviour if and only if (and because) they are causal relations that link the working parts that are constitutively relevant to organism behaviour. In this paper, I argue that the causal-linking account is inadequate because it neglects the constitutive relevance of anatomical relations that organise the working parts of a behaving organism. I demonstrate this by considering a case study where the anatomical organisation of the barn owl (Tyto alba) is constitutively relevant to their mechanism for sound localization. The anatomical organisation of this mechanism is best understood as the back-and-forth flow of task information across 7 “levels of anatomy” (a notion that I distinguish from levels of mechanism). A further implication, I conclude, is that at least some of the interlevel structure of neuroscientific explanation is accounted for by levels of anatomy, not levels of mechanism. (shrink)

Despite the radical importance of embryology in the development of organicism, developmental biology remains philosophically underexplored as a theoretical and empirical resource to clarify the nature of organisms. This paper discusses how embryology can help develop the organisational definition of the organism as a differentiated, functionally integrated, and autonomous system. I distinguish two conceptions of development in the organisational tradition that yield two different conceptions of the organism: the life-history view claims that organisms can be considered as such during their (...) whole ontogeny; the constitutive view distinguishes two periods in the life history, a period of generation and a period of self-maintenance of a constitutive organisation. Arguing in favour of the constitutive view, it will be claimed that the organisational criteria for the definition of organism (i.e., differentiation, functional integration, and autonomy) can only be applied to the developmental system when it has entered the period of self-maintenance of a constitutive organisation. Under the light of current research in developmental biology, it is possible to make explicit how organisms come to be as organisms. To this end, I explore key ontogenetic events that help us clarify the core aspects of animal organisation and allow us to identify the developmental stage that marks the ontological transition between an organism in potency and an organism in actuality. The structure of this ontogenetic unfolding parallels the conceptual structure of the very notion of organism; the generation of the being of a particular organism parallels its definition. (shrink)

Despite the radical importance of embryology in the development of organi- cism, developmental biology remains philosophically underexplored as a theoretical and empirical resource to clarify the nature of organisms. This paper discusses how embryology can help develop the organisational definition of the organism as a differentiated, function- ally integrated, and autonomous system. I distinguish two conceptions of development in the organisational tradition that yield two different conceptions of the organism: the life- history view claims that organisms can be considered as (...) such during their whole ontogeny; the constitutive view distinguishes two periods in the life history, a period of generation and a period of self-maintenance of a constitutive organisation. Arguing in favour of the con- stitutive view, it will be claimed that the organisational criteria for the definition of organ- ism (i.e., differentiation, functional integration, and autonomy) can only be applied to the developmental system when it has entered the period of self-maintenance of a constitutive organisation. under the light of current research in developmental biology, it is possible to make explicit how organisms come to be as organisms. To this end, I explore key onto- genetic events that help us clarify the core aspects of animal organisation and allow us to identify the developmental stage that marks the ontological transition between an organism in potency and an organism in actuality. The structure of this ontogenetic unfolding paral- lels the conceptual structure of the very notion of organism; the generation of the being of a particular organism parallels its definition. (shrink)

The organism is neither a discovery like the circulation of the blood or the glycogenic function of the liver, nor a particular biological theory like epigenesis or preformationism. It is rather a concept which plays a series of roles, sometimes masked, often normative, throughout the history of biology. Indeed, it has often been presented as a key-concept in life science and its ‘theorization’, but conversely has also been the target of influential rejections: as just an instrument of transmission for the (...) selfish gene, but also, historiographically, as part of an outdated ‘vitalism’. Indeed, the organism, perhaps because it is experientially closer to the ‘body’ than to the ‘molecule’, is often the object of quasi-affective theoretical investments presenting it as essential, as the pivot of a science or a particular approach to nature, while other approaches reject or attack it with equal force, assimilating it to a mysterious ‘vitalist’ ontology of extra-causal forces, or other pseudo-scientific doctrines. I do not seek to adjudicate between these debates, either regarding scientific validity or historical coherence; nor do I return to the well-studied issue of the organism-mechanism tension in biology. Recent scholarship has begun to discuss the emergence and transformation of the organism concept, but has not emphasized the way the latter is a shifting, ‘go-between’ concept – invoked as ‘natural’ by some thinkers to justify their metaphysics, but then presented as value-laden by others, over and against the natural world. The organism as go-between concept is also a hybrid, a boundary concept or a limit case, which continues to function in different contexts – as a heuristic, an explanatory challenge, a model of order, of regulation, etc. – despite having frequently been pronounced irrelevant and reduced to molecules or genes. Yet this perpetuation is far removed from any ‘metaphysics of organism’, or organismic biology. (shrink)

Over the past decades, self-assembly has attracted a lot of research attention and transformed the relations between chemistry, materials science and biology. The paper explores the impact of the current interest in self-assembly techniques on the traditional debate over the nature of life. The first section describes three different research programs of self-assembly in nanotechnology in order to characterize their metaphysical implications: (1) Hybridization (using the building blocks of living systems for making devices and machines) ; (2) Biomimetics (making artifacts (...) mimicking nature); (3) Integration (a composite of the two previous strategies). The second section focused on the elusive boundary between self-assembly and self-organization tries to map out the various positions adopted by the promoters of self-assembly on the issue of vitalism. (shrink)

This paper addresses the remarkable longevity of the idea of vitalism in the biological sciences and beyond. If there is to be a renewed vitalism today, however, we need to ask – on what kind of original conception of life should it be based? This paper argues that recent invocations of a generalized, processual variety of vitalism in the social sciences and humanities above all, however exciting in their scope, miss much of the basic originality – and interest – of (...) the vitalist perspective itself. The paper argues that any renewed spirit of vitalism in the contemporary era would have to base itself on the normativity of the living organism rather than on any generalized conceptions of process or becoming. In the terms of the paper, such a vitalism would have to be concrete and ‘disciplinary’ rather than processual or generalized. Such a vitalism would also need to accommodate, crucially, the pathic aspects of life – pathology, sickness, error; in short everything that makes us, as living beings, potentially weak, without power, at a loss. Sources for such a pathic vitalism might be found above all in the work of Georges Canguilhem – and Friedrich Nietzsche – rather than primarily in Bergson, Whitehead or Deleuze. (shrink)

There is a familiar opposition between a ‘Scientific Revolution’ ethos and practice of experimentation, including experimentation on life, and a ‘vitalist’ reaction to this outlook. The former is often allied with different forms of mechanism – if all of Nature obeys mechanical laws, including living bodies, ‘iatromechanism’ should encounter no obstructions in investigating the particularities of animal-machines – or with more chimiatric theories of life and matter, as in the ‘Oxford Physiologists’. The latter reaction also comes in different, perhaps irreducibly (...) heterogeneous forms, ranging from metaphysical and ethical objections to the destruction of life, as in Margaret Cavendish, to more epistemological objections against the usage of instruments, the ‘anatomical’ outlook and experimentation, e.g. in Locke and Sydenham. But I will mainly focus on a third anti-interventionist argument, which I call ‘vitalist’ since it is often articulated in the writings of the so-called Montpellier Vitalists, including their medical articles for the Encyclopédie. The vitalist argument against experimentation on life is subtly different from the metaphysical, ethical and epistemological arguments, although at times it may borrow from any of them. It expresses a Hippocratic sensibility – understood as an artifact of early modernity, not as some atemporal trait of medical thought – in which Life resists the experimenter, or conversely, for the experimenter to grasp something about Life, it will have to be without torturing or radically intervening in it. I suggest that this view does not have to imply that Nature is something mysterious or sacred; nor does the vitalist have to attack experimentation on life in the name of some ‘vital force’ – which makes it less surprising to find a vivisectionist like Claude Bernard sounding so close to the vitalists. (shrink)

This paper seeks to characterize how the study of nutrition processes contributed to revisit the problem of vital organization in the late eighteenth century. It argues that focusing on nutrition leads to reformulate the problem of the relation between life and organization in terms of processes, rather than static or given structures. This nutrition-centered approach to life amounts to acknowledge the specific strategic role nutrition played in the development of a materialist approach to the generation of vital organization. The paper (...) proposes a clarification of the multiple meanings of the concept of organization in the context of Enlightenment physiology and nascent biology, before focusing on the century long analogy between nutrition and generation. It shows how, by contrasting different uses of this analogy, nutrition was employed as a key vital phenomenon in the development of epigenetic theories of generation, i.e. how a nutritive modeling of generation was used in the undermining of preformationism. To this purpose I contrast two seemingly opposite theories of generation, Buffon’s and Bonnet’s, and show that despite the obvious metaphysical discontent, their views of generation share a common mechanical conceptual frame in which nutrition is conflated with growth and repair. I then turn to the role nutrition played in the epigenetic conception of generation in C. F. Wolff’s embryology and analyze this rival understanding of nutrition as an organizing process. (shrink)

Mikhail Bakhtin’s 1926 essay, “Contemporary Vitalism,” includes Bergson alongside Driesch in a short list of “the most published representatives of vitalism in Western Europe,” and, indeed, Bakhtin’s critique of Driesch is intended to undermine what he calls the “conceptual framework” of “contemporary vitalism” as a whole (The crisis of modernism: Bergson and the vitalist controversy. Eds. Frederick Burwick and Paul Douglass. Cambridge University Press, New York, 1992, p 81). The conceptual framework that Driesch and Bergson are supposed to have shared (...) in common consists at bottom, for Bakhtin, in the ontological commitment to the autonomy of life, “its independence, its disconnectedness from physical-chemical phenomena” (81). This has long been understood as the defining mark of vitalism, at least in the mind of its critics: the contention that matter and the mechanical models that track it are insufficient to the reality of biological forms, and that the explanation of life therefore requires the postulation of a non-mechanical, possibly immaterial, uniquely vital principle, force, substance, or property. Recent scholarship has made considerable headway in complicating these pictures by attending to earlier and subtler forms of materialism, and by distinguishing between different types of vitalism and drawing out the heuristic or scientific utility of some of them (Wolfe, Eidos 14: 212–235, 2011, Antropol Exp 17(13): 215–224, 2017; cf. Wolfe and Normandin, Vitalism and the scientific image in post-enlightenment life science, 1800–2010. Springer, Dordrecht, 2013). The focus of some of this work has been on the critical revaluation of Driesch himself (Bognon et al., Kairos J Philos Sci 20(1): 113–140, 2018). Yet the status of Bergson’s commitment to the existence of a vital principle remains underdeveloped. In the midst of what some are calling a “Bergson renaissance,” I think that it calls for the same kind of critical reappraisal (Ansell-Pearson, Bergson: thinking beyond the human condition. Bloomsbury, New York, 2018: 1; cf. Lundy, Deleuze’s Bergsonism. Edinburgh University Press, Edinburgh, p 5, 2018). The aim of this paper is to attempt the outline of an answer to that call. I begin with a brief summary of Driesch’s vitalism, then I reconstruct Bergson’s underappreciated critique of internal finality, or what Kant called inner purposiveness, and locate in it a subterranean criticism of vital principles of the Drieschian variety as well. Two consequences follow: first, if Bergson is to be considered a vitalist, it cannot be in the Drieschian sense and we are therefore wrong to associate the two; and second, if Bergson is to be considered a vitalist, then his vitalism has to be understood—somewhat counterintuitively, and certainly contra Driesch—on the basis of a principle external to the ostensible individuality of biological forms. (shrink)

Alfred I. Tauber (ed.), Organism and the Origins of Self. Dordrecht, Netherlands: Kluwer Academic Publishers, 1991. xix + 384 pp., US$ 110.00 (US$ 25.00 paperback). This is a fascinating book based on a 1990 symposium at Boston University. It promises to change the way one conceives of the organism. The authors start from different specializations but provide a most tantalizing feast of ideas. Richard Lewontin commences the book with a strange foreword. Lewontin submits that the concern with the "self and (...) private identity in modern biology is ... only one manifestation of the ideology of individualism that is a shibboleth of our particular [bourgeois] form of social organization" (p. xix). If this is the case, the reader should stop reading the book and ask for her money back. But I advise patience. Tauber's introduction is a mixture of the history of the medical notion of disease and the advocacy of a dialectical concept of the self as the interpenetration of part and whole. Tauber highlights Elie Metchnikoff's appealing idea of phagocytosis as just one form of the active organism striving to attain harmony among competing cells. (shrink)

Foreword by Oliver Sacks Kurt Goldstein (1878-1965) was already an established neuropsychologist when he emigrated from Germany to the United States in the 1930s. This book, his magnum opus and widely regarded as a modern classic in psychology and biology, grew out of his dissatisfaction with traditional natural science techniques for analyzing living beings. It offers a broad introduction to the sources and ranges of application of the "holistic" or "organismic" research program that has since become a standard part of (...) biological thought. Goldstein was especially concerned with the breakdown of organization and the failure of central controls that take place in catastrophic responses to situations such as physical or mental illness. But he was equally attuned to the amazing powers of the organism to readjust to such catastrophic losses, if only by withdrawal to a more limited range that it could manage by a redistribution of its reduced energies, thus reclaiming as much wholeness as new circumstances allowed. Goldstein's theses in The Organism have had an important impact on philosophical and psychological thought throughout the twentieth century, as evidenced in the work of Maurice Merleau-Ponty, Georges Canguilhem, Ernst Cassirer, and Ludwig Binswanger. (shrink)

Living systems are complex systems made of components that tend to degrade, but nonetheless they maintain themselves far from equilibrium. This requires living systems to extract energy and materials from the environment and use them to build and repair their parts. They do so by regulating their activities on the basis of their internal and external conditions in ways that allow them to keep living. The philosophical and theoretical approach discussed in this book aims to explain these features of biological (...) systems by appealing to their organization. One of its distinctive features is that it addresses classical and more recent issues in philosophy of biology, from origins and definitions of life to biological teleology and functions, from an original perspective mainly focused on the living system, its physiology and behavior, rather than evolution. The book discusses and revises the conceptual foundations of this approach and presents an updated version of it. (shrink)

This essay argues for the importance of an organismic perspective in plant biology and considers some of its implications. These include an increased attention to plant-environment interaction and an emphasis on integrated approaches. Furthermore, this essay contextualizes the increased emphasis on the concept of organism in recent years and places the concept in a longer history. Recent developments in biology and worsening environmental crises have led researchers to study plant responses to changing environments with whole plant approaches that situate plants (...) in their environments, emphasizing the intricate and dynamic interaction between them. This renewed attention to the organism recalls the debates of the early twentieth century, when organicism was one of the three main frameworks in biology (along with vitalism and mechanism). Some scholars see this renewed importance today as a “return” of this earlier period. This essay argues that including insights from plant biology will benefit philosophy of biology research that examines the concept of organism and organicism now and in earlier periods. A comprehensive account of the concept of organism should involve a botanical conception of the organism as well as a zoological one (which is more frequently considered). Although this essay does not aim to present a conceptual analysis, it presents examples of how an organismic perspective can be useful for understanding concepts (such as phenotype, stress, etc.) and research processes (such as experiment set-ups, data processes, etc.) in plant biology. Philosophy of biology investigations that aim at a comprehensive understanding of the concept of organism can benefit greatly from examinations of cases in plant biology, both now and in the past. (shrink)

In this paper, we set out to develop a theoretical and conceptual framework for the new field of Radical Embodied Cognitive Neuroscience. This framework should be able to integrate insights from several relevant disciplines: theory on embodied cognition, ecological psychology, phenomenology, dynamical systems theory, and neurodynamics. We suggest that the main task of Radical Embodied Cognitive Neuroscience is to investigate the phenomenon of skilled intentionality from the perspective of the self-organization of the brain-body-environment system, while doing justice to the phenomenology (...) of skilled action. In previous work, we have characterized skilled intentionality as the organism's tendency toward an optimal grip on multiple relevant affordances simultaneously. Affordances are possibilities for action provided by the environment. In the first part of this paper, we introduce the notion of skilled intentionality and the phenomenon of responsiveness to a field of relevant affordances. Second, we use Friston's work on neurodynamics, but embed a very minimal version of his Free Energy Principle in the ecological niche of the animal. Thus amended, this principle is helpful for understanding the embeddedness of neurodynamics within the dynamics of the system “brain-body-landscape of affordances.” Next, we show how we can use this adjusted principle to understand the neurodynamics of selective openness to the environment: interacting action-readiness patterns at multiple timescales contribute to the organism's selective openness to relevant affordances. In the final part of the paper, we emphasize the important role of metastable dynamics in both the brain and the brain-body-environment system for adequate affordance-responsiveness. We exemplify our integrative approach by presenting research on the impact of Deep Brain Stimulation on affordance responsiveness of OCD patients. (shrink)

Abstract“Development” suggests that there is something that is developing, or changing over time. We can ask about temporal boundaries of that developmental process, asking when development begins or ends and whether it has defined stages along the way, for example. We can ask about spatial boundaries as well: where does the developing object start and end? For this article, I ask about the boundary definition of the developing organism in particular. What is an individual organism, and what defines it as (...) the same organism as it changes over time? In particular, how has this been answered historically: how have researchers described and explained what an individual developing organism is? This article explores ideas and approaches especially starting in the late 19th century, and in particular looks at the role of “organization.”. (shrink)

This article presents a new hypothesis on the origin of life on Earth. According to this hypothesis, life arose within the limits of a particular material system representing a set of specific local environments integrated by a common circulating liquid medium where relatively short RNA molecules, viroid-like particles, are replicated with great accuracy. In each of the local environments, the synthesis of certain substances that are required for accurate replication and survival of the RNAs is carried out. The system, which (...) we called “diffuse organism,” is, in essence, a very rough and bulky analog of the structural-functional organization of the cell’s biosynthetic machinery. The diffuse organism was an organismal and evolving system at the same time. It seems that only such a system that has emerged in the only specimen as a result of a set of chance events operating under a system of universal physical and chemical laws was able to give rise to life and evolution by means of biological selection. The outlined scenario for the origin of life allows us to narrow down the still insuperable gap between prebiological chemistry and the first living systems without devising conceptions unrelated to the realities of life. (shrink)

The modernist movement has been regarded as representing a crisis point in Western thought. This volume looks at that crisis in terms of its reinterpretation of ideas concerning vitalism: the animation of the universe, whether spiritual or based in physical energies) of the universe. Beginning with vitalism's historical background in the enlightenment and the nineteenth century, and moving through scientific, philosophical and literary disciplines, the contributors chart the progress of vitalism and its influence on modernist thought. The focal point (...) is the work of Henri Bergson, whose part in this powerful reinterpretation had a considerable bearing on European and American intellectual life, and yet led to a vehement rejection of his work. A previously untranslated and little-known essay by Bakhtin will be of special interest in this stimulating collection, which includes original contributions from leading scholars in literature, the history of science, biology and philosophy, and comprises a wide-ranging reassessment of 'the perpetual crises of modernity'. The modernist movement has been regarded as representing a crisis point in Western thought. This volume looks at that crisis in terms of its reinterpretation of ideas concerning vitalism: the animation of the universe, whether spiritual or based in physical energies) of the universe. Beginning with vitalism's historical background in the enlightenment and the nineteenth century, and moving through scientific, philosophical and literary disciplines, the contributors chart the progress of vitalism and its influence on modernist thought. The focal point is the work of Henri Bergson, whose part in this powerful reinterpretation had a considerable bearing on European and American intellectual life, and yet led to a vehement rejection of his work. A previously untranslated and little-known essay by Bakhtin will be of special interest in this stimulating collection, which includes original contributions from leading scholars in literature, the history of science, biology and philosophy, and comprises a wide-ranging reassessment of 'the perpetual crises of modernity'. (shrink)

Securing the internet has arguably become paradigmatic for modern security practice, not only because modern life is considered to be impossible or valueless if disconnected, but also because emergent cyber-relations and their complex interconnections are refashioning traditional security logics. This paper analyses European modes of governing geared toward securing vital, emergent cyber-systems in the face of the interconnected emergency. It develops the concept of ‘bureaucratic vitalism’ to get at the tension between the hierarchical organization and reductive knowledge frames of security (...) apparatuses on the one hand, and the increasing desire for building ‘resilient’, dispersed, and flexible security assemblages on the other. The bureaucratic/vital juxtaposition seeks to capture the way in which cybersecurity governance takes emergent, complex systems as object and model without fully replicating this ideal in practice. Thus, we are concerned with the question of what happens when security apparatuses appropriate and translate vitalist concepts into practice. Our case renders visible the banal bureaucratic manoeuvres that seek to operate upon security emergencies by fostering connectivities, producing agencies, and staging exercises. (shrink)

This article outlines an epistemological perspective to understand the organism as a temporally changing whole. To analyze the mental faculties involved, the organism’s development and persisting existence is differentiated into four interdependent aspects: descent, future existence, persistent species, and environmentally adapted physical appearance. It is outlined that these aspects are recognized by comparative memory, concept-guided anticipation, conceptual thinking, and sensory perception, respectively. Furthermore, it is pointed out that these aspects correspond to the famous four Aristotelian “causes” or principles of explanation. (...) The descent of an organism corresponds to Aristotle’s efficient principle (“where does it come from?”), its future existence to the final principle (“what is if for?”), its physical structure to the material principle (“out of what is it?”) and its persistent species to the formal principle (“what is it?”). Aristotle regarded the unity of the efficient, formal and final principle as the ontological cause of the organism and called it the “soul” (psyche), while the material principle can be understood to represent its “body” (soma). I suggest that Aristotle’s “soul” corresponds to three of the four mental faculties required for cognition of a self-maintaining organism. I argue that in a Kantian perspective, the Aristotelian “soul” represents the condition for recognizing an organism at all. Therefore, the Aristotelian principle of life becomes intelligible and even empirically observable through the inner sense. In summary, I suggest that the four aspects of the organism described here can be viewed as the general, epistemological and ontological principle of the organism, the Bio-Logos. (shrink)

In the period of the high and late Enlightenment, the human sciences were reformed based on ideas, methods, and assumptions drawn from the life sciences. The goal was to improve the human sciences by naturalizing them, injecting them with the spirit that animated the search for the principles of life in biology. Many Enlightenment thinkers took interest in the agenda set by a loose group of natural philosophers known as vitalists, which included Georges-Louis Leclerc de Buffon, Paul Barthez, (...) Charles Bonnet, Alexander von Humboldt, Horace-Bénédict de Saussure, and Toberg Olaf Bergman. These vitalists sought to reformulate the concept of matter and proposed theories that resurrected the Renaissance and classical biological ideas rejected by the mechanists. This chapter explores how biological vitalism was utilized by Enlightenment thinkers to formulate strikingly modern concepts of the human sciences, focusing on Adam Smith's Wealth of Nations and Johann Gottfried Herder's Ideen. In particular, it explores how Enlightenment vitalism inspired the two men's conception of a science of humanity, that is, their use of analogy, semiotics, and the epistemology that supported it. (shrink)

THE ENLIGHTENMENT IS DISTINGUISHED from other periods of history by two major characteristics: 1) the widespread belief that it was superior morally and intellectually to all those periods which preceded it, and 2) the conviction that human faculties, reason or moral sense, are primarily responsible for this achievement. The Enlightenment was marked, furthermore, by radical change in the organization of society and by rapid progress in the applications of scientific technology to the production of goods and services. Since (...) political and ecclesiastical authorities were challenged during the Enlightenment, revolutions, both democratic and industrial, have been its fruit. Inherited traditions and established institutions were often overthrown or overhauled in order to release the human energies, ideas, and values which promoted the erection of new institutions. (shrink)

The species of vitalism discussed here, to immediately rule out two possible misconceptions, is neither the feverish cosa mentale found in ruminations on ‘biopolitics’ and fascism – where it alternates quickly between being a form of evil and a form of resistance, with hardly any textual or conceptual material to discuss – nor the opaque, and less-known form in which it exists in the worlds of ‘Theory’ in the humanities, perhaps closely related to the cognate, ‘materiality’. Rather, vitalism here is (...) a malleable construct, often with a poisonous reputation, hovering in the realms of the philosophy of biology, the history of medicine, and the scientific background of the Radical Enlightenment. This is a more vital vitalism, or at least a more ‘biologistic’, ‘embodied’, medicalized vitalism. I first distinguish between what I would call ‘substantival’ and ‘functional’ forms of vitalism, as applied to the eighteenth century. Substantival vitalism presupposes the existence of something like a vital force which either plays a causal role in the natural world as studied by scientific means, or remains a kind of hovering, extra-causal entity. Functional vitalism tends to operate ‘post facto’, from the existence of living bodies to the desire to find explanatory models that will do justice to their uniquely ‘vital’ properties in a way that fully mechanistic models cannot. I discuss some representative figures of the Montpellier school as being functional rather than substantival vitalists. A second point concerns the reprisal of vitalism in ‘late modernity’; from Hans Driesch to Georges Canguilhem. I suggest that in addition to the substantival and functional varieties, we then encounter a third, more existential form of vitalism, articulated by Canguilhem, in which vitalism is a kind of attitude towards Life. All of this, I hope, argues for a form of vitalism which is neither tedious scientism nor dangerous political rhetoric of health and sickness; instead, a vitalism with its own discreet charm. (shrink)

Our aim in this article is to attempt to discuss propagating organization of process, a poorly articulated union of matter, energy, work, constraints and that vexed concept, “information”, which unite in far from equilibrium living physical systems. Our hope is to stimulate discussions by philosophers of biology and biologists to further clarify the concepts we discuss here. We place our discussion in the broad context of a “general biology”, properties that might well be found in life anywhere in the cosmos, (...) freed from the specific examples of terrestrial life after 3.8 billion years of evolution. By placing the discussion in this wider, if still hypothetical, context, we also try to place in context some of the extant discussion of information as intimately related to DNA, RNA and protein transcription and translation processes. While characteristic of current terrestrial life, there are no compelling grounds to suppose the same mechanisms would be involved in any life form able to evolve by heritable variation and natural selection. In turn, this allows us to discuss at least briefly, the focus of much of the philosophy of biology on population genetics, which, of course, assumes DNA, RNA, proteins, and other features of terrestrial life. Presumably, evolution by natural selection—and perhaps self-organization—could occur on many worlds via different causal mechanisms. Here we seek a non-reductionist explanation for the synthesis, accumulation, and propagation of information, work, and constraint, which we hope will provide some insight into both the biotic and abiotic universe, in terms of both molecular self reproduction and the basic work energy cycle where work is the constrained release of energy into a few degrees of freedom. The typical requirement for work itself is to construct those very constraints on the release of energy that then constitute further work. Information creation, we argue, arises in two ways: first information as natural selection assembling the very constraints on the release of energy that then constitutes work and the propagation of organization. Second, information in a more extended sense is “semiotic”, that is about the world or internal state of the organism and requires appropriate response. The idea is to combine ideas from biology, physics, and computer science, to formulate explanatory hypotheses on how information can be captured and rendered in the expected physical manifestation, which can then participate in the propagation of the organization of process in the expected biological work cycles to create the diversity in our observable biosphere. Our conclusions, to date, of this enquiry suggest a foundation which views information as the construction of constraints, which, in their physical manifestation, partially underlie the processes of evolution to dynamically determine the fitness of organisms within the context of a biotic universe. (shrink)

Enactivism and ecological psychology converge on the relevance of the environment in understanding perception and action. On both views, perceiving organisms are not merely passive receivers of environmental stimuli, but rather form a dynamic relationship with their environments in such a way that shapes how they interact with the world. In this paper, I suggest that while enactivism and ecological psychology enjoy a shared specification of the environment as the cognitive domain, on both accounts, the structure of the environment, itself, (...) is unspecified beyond that of contingent relations with the species-typical sensorimotor capacities of perceiving organisms. This lack of specification creates a considerable gap in theory regarding the organization of organisms as coupled with their environments. I argue that this gap can be filled by drawing from resources in developmental systems theory, namely, specifying the environmental state-space as a developmental niche that shapes and is shaped by individual organisms over developmental and, on a population scale, evolutionary time. Defining the environment as an organism’s developmental niche makes it clearer how and why certain contingencies have arisen, in turn, strengthening a joint appeal to both enactivism and ecological psychology as theories asserting complementarity between organisms and their environments. (shrink)

Even if the concept of organization is increasingly recognized as crucially important to (philosophy of) biology, the fear of thereby collapsing into vitalism, understood as the metaphysical thesis that “life” involves special principles irreducible to (and that perhaps even run counter to) the principles governing the physical order, has persisted. In trying to overcome this tension, Georges CanguilhemCanguilhem, G. endorsed an attitudinal form of vitalism. This “attitudinal stance” (a term coined by Charles Wolfe) shifts the issue of organization away from (...) ontological commitments regarding the nature of things as they are in themselves, in favor of epistemologicalEpistemology issues concerning the stance of the knowing subjectSubject. However, it is based on some epistemological tenets that deserve further examination. Firstly, in spite of its anti-Cartesian spirit, the attitudinal stance implicitly relies on a CartesianCartesianism perspective on the relation between subject and object. Secondly, it rests on the idea that some objects can meaningfully be identified as persisting individuals—living organisms—in a way in which others cannot, even if it denies that the capacity to be meaningfully identified as such reflects an actual property of them. This chapter outlines a possible alternative viewpoint that takes these challenges to heart by developing a co-constitutive picture of the relation between subject and object—a picture based on Georges Canguilhem’s own theory of judgment, but supplemented by Immanuel KantKant, I.’s transcendental logic. Most fundamentally, it is argued that the (self-)organization of living beingsLiving beings draws attention to and is structurally intertwined with the (self-)organization of the thinking subject’s rational (i.e., logical, conceptual, judging) capacities. (shrink)

This far-reaching study redraws the intellectual map of the Enlightenment and boldly reassesses the legacy of that highly influential period for us today. Peter Hanns Reill argues that in the middle of the eighteenth century, a major shift occurred in the way Enlightenment thinkers conceived of nature that caused many of them to reject the prevailing doctrine of mechanism and turn to a vitalistic model to account for phenomena in natural history, the life sciences, and chemistry. As he (...) traces the ramifications of this new way of thinking through time and across disciplines, Reill provocatively complicates our understanding of the way key Enlightenment thinkers viewed nature. His sophisticated analysis ultimately questions postmodern narratives that have assumed a monolithic Enlightenment—characterized by the dominance of instrumental reason—that has led to many of the disasters of modern life. (shrink)

Biology lacks a central organism concept that unambiguously marks the distinction between organism and non-organism because the most important questions about organisms do not depend on this concept. I argue that the two main ways to discover useful biological generalizations about multicellular organization--the study of homology within multicellular lineages and of convergent evolution across lineages in which multicellularity has been independently established--do not require what would have to be a stipulative sharpening of an organism concept.

0. Philippe Huneman and Charles T. Wolfe: Introduction 1. Tobias Cheung, “What is an ‘organism’? On the occurrence of a new term and its conceptual transformations 1680-1850” 2. Charles T. Wolfe, “Do organisms have an ontological status?” 3. John Symons, “The individuality of artifacts and organisms” 4. Thomas Pradeu, “What is an organism? An immunological answer” 5. Matteo Mossio & Alvaro Moreno, “Organisational closure in biological organisms” 6. Laura Nuño de la Rosa, “Becoming organisms. The organisation of development and the (...) development of organisation” 7. Denis Walsh, “Two Neo-Darwinisms” 8. Philippe Huneman, “Assessing the prospects for a return of organisms in evolutionary biology” 9. Johannes Martens, “Organisms in evolution” 10. Susan Oyama, “Biologists behaving badly: Vitalism and the language of language” . (shrink)

ArgumentEighteenth-century Montpellerian vitalism and contemporaneous French “vitalist” materialism, exemplified by the medical and biological materialism of La Mettrie and Diderot, differ in some essential aspects from some later forms of vitalism that tended to postulate immaterial vital principles or forces. This article examines the arguments defending the existence of vital properties in living organisms presented in the context of eighteenth-century French materialism. These arguments had recourse to technological metaphors and analogies, mainly clockworks, in order to claim that just as machines (...) can have functional properties which its parts do not possess, so living organisms can, as material entities, also have organic or vital properties which its material parts do not possess. Such arguments, with the help of a healthy dose of epistemological scepticism, tend to strike a balance between two positions concerning the ontology of life which we now tend to label “vitalism” and “emergentism.” Although there is nothing inconsistent in viewing vital properties as emergent, some ambiguity results if one does not draw a clear distinction between properties and functions. The philosophical problems related to these ambiguities are revealed in Diderot's apparent hesitation concerning sentience as “a general property of matter or the product of organization.”. (shrink)