Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

Taken as a whole, the volume provides an unparalleled survey of all the topical areas, major methods, and stances in the philosophy of science.

SummaryEllis, Jardine and Putnam have argued that the would‐be scientific realist can only avoid being a metaphysical realist by becoming an “internal realist” . While metaphysical realism is unattractive, the approaches to truth offered by Ellis, Jardine and Putnam are quite unacceptable. However, the is no reason to think that one who wishes to be a scientific realist is limited to these two options.

First published in 1985. Routledge is an imprint of Taylor & Francis, an informa company.

First published in 2002. Routledge is an imprint of Taylor & Francis, an informa company.

We all think that science is special. Its products—its technological spin-off—dominate our lives which are thereby sometimes enriched and sometimes impoverished but always affected. Even the most outlandish critics of science such as Feyerabend implicitly recognize its success. Feyerabend told us that science was a congame. Scientists had so successfully hood-winked us into adopting its ideology that other equally legitimate forms of activity—alchemy, witchcraft and magic—lost out. He conjured up a vision of much enriched lives if only we could free (...) ourselves from the domination of the ‘one true ideology’ of science just as our ancestors freed us from the domination of the Church. But he told us these things in Switzerland and in California happily commuting between them in that most ubiquitous product of science—the aeroplane. (shrink)

Originally published in 1980. What is time? How is its structure determined? The enduring controversy about the nature and structure of time has traditionally been a diametrical argument between those who see time as a container into which events are placed, and those for whom time cannot exist without events. This controversy between the absolutist and the relativist theories of time is a central theme of this study. The author's impressive arguments provide grounds for rejecting both these theories, firstly by (...) establishing that 'empty' time is possible, and secondly by showing, through a discussion of the structure of time which involves considering whether time might be cyclical, branching, beginning or non-beginning, that the absolutist theory of time is untenable. This book then advances two new theories, and succeeds in shifting the traditional debate about time to a consideration of time as a theoretical structure and as a theoretical framework. (shrink)

The point of departure for all discussions of nonstatistical explanation in the philosophy of science has been the deductive‐nomological or covering law model of explanation that was given its most influential exposition by Carl Hempel, who was also the pioneering figure in the discussion of statistical explanation (see statistical explanation). On this account, to explain a particular event, we cite other particular events together with a general law or laws which "cover" what we want to explain. For example, we might (...) explain why a balloon expanded when placed on a radiator, by citing the fact that the radiator was hot together with the relevant laws relating heat to expansion. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

We think that science is special: its products ‐ technological spin‐offs ‐ dominate our lives. Sometimes it enriches our lives; sometimes it impoverishes them or even takes them away. For better or for worse, no institution has had more impact on the character of our existence this millennium than science. Penicillin, computers, atomic bombs make modern life modern life.

David Hume is the greatest figure in the empiricist tradition in philosophy and was a particular source of inspiration for the logical positivists (see logical positivism). Hume was born in 1711 and entered Edinburgh University at the age of 12. After graduating, he had a varied career in commerce, diplomacy, as a librarian, and as a writer of history. Twice he was secretary to General St Clair and on one occasion set off with him on an expedition to drive the (...) French out of Canada. Forced back by the wind, it was decided instead to make a brief incursion on the coast of Brittany. This failed, for the expedition had maps of Canada, but none of Brittany. During a three‐year stay in France he wrote his major philosophical work Treatise of Human Nature. It appeared in 1739 and, in his own words, “fell dead‐born from the Press.” His Inquiry Concerning Human Understanding, which was intended to be a more popular version of book I of his Treatise, was published in 1748 but was only a little more favorably received. His six‐volume History of England, on the other hand, was a great success. He died in 1776, never having succeeded in his ambition to be appointed to a professorship of philosophy in Scotland, due to his religious skepticism. (shrink)

Although much evidence indicates that young infants perceive unitary objects by analyzing patterns of motion, infantsÕ abilities to perceive object unity by analyzing Gestalt properties and by integrating distinct views of an object over time are in dispute. To address these controversies, four experiments investigated adultsÕ and infantsÕ perception of the unity of a center-occluded, moving rod with misaligned visible edges. Both alignment information and depth information affected adultsÕ and infantsÕ perception of object unity in similar ways, and infants perceived (...) object unity by integrating information about object features over time. However, infants perceived a moving, misaligned, three-dimensional object as indeterminate in its connectedness, whereas adults perceived it as connected behind the occluder. These findings indicate that the effectiveness of common motion in specifying unified surfaces across an occluder is reduced by misalignment of edges. Alignment information enhances perception of object unity either by serving directly as information for unity or by optimizing the detectability of motion-carried information for unity. In addition, young infants are able to retain information about edge orientation over short intervals in determining connectedness via a process of spatiotemporal integration. Ó 2003 Elsevier Science (USA). All rights reserved. (shrink)

A project on teaching business ethics at The Wharton School concluded that ethics should be directly incorporated into key MBA courses and taught by the core business faculty. The project team, comprised of students, ethics faculty and functional business faculty, designed a model program for integrating ethics. The project was funded by the Exxon Education Foundation.The program originates with a general introduction designed to familiarize students with literature and concepts pertaining to professional and business ethics and corporate social responsibility. This (...) may be accomplished through orientation sessions, readings, packages, short classes and lectures. (shrink)