This book uses the writings of Syed Alam Khundmiri to look at issues such as: Islamic traditionalism in the context of meodernization; Islamic theology and politics; and Western and Indian notions of secularism.

The main objective of this paper is to assess the attitude of a group of Malaysian business students towards business ethics. The survey results indicate that the respondents in general are of the opinion that the businesses in Malaysia consider ethics as secondary. A greater emphasis on ethical values in the business curricular has been strongly supported by the respondents. Moreover, the majority of the respondents believe that moral/ethical education and top management attitudes are the most important factors influencing ethical (...) standards in business practices. (shrink)

A review of economic thought since the sixteenth century reveals two streams of economic discourse, dirigisme and laissez-faire. Starting with the mercantilists, dirigiste approaches to economics embrace the real-world complexity of commodities that often differ greatly in attributes that are growth- and rent- augmenting. Most importantly, this means that free trade is likely to be polarising: it concentrates growth- and rent-augmenting commodities in countries that already enjoy a head start in these commodities. Advanced countries, therefore, support laissez-faire, while lagging countries (...) tend to support dirigisme. In order to rationalise their laissez-faire stance, advanced countries began developing a new economic discourse that strips commodities of their complexity. The foundations for this ideological reconstruction of economics were first laid by Adam Smith; this process eventually reached its climax with the neoclassical economists who stripped commodities down to one attribute: their capital intensity. In opposition to this laissez-faire economics, other writers, supportive of the interests of lagging countries, brought complexity back into their economic discourse; they argued that lagging countries had a fighting chance of catching up to advanced economies only by indigenising a growing array of growth- and rent-augmenting commodities. (shrink)

The Hon’ble Supreme Court of India, in a landmark judgment, scrapped a draconian law [Section 66 (A)] that gave the police absolute power to put behind bars anybody who was found posting offensive or annoying comments online. This paper aims to examine the take of people on the “Free Speech via Social Media” issue and their attitude towards the way sensitive messages/information are posted, shared and forwarded on social media, especially, Facebook.,The research was carried out on a sample of 200 (...) social media users, all picked up randomly, from five Indian states/Union Territories. Data were collected through a questionnaire, and users were contacted through e-mail. Data collected were analyzed through the Kolmogorov–Smirnov (K-S) Z test.,The findings indicate that hate posts/messages are on the rise, and more and more users are joining in. Besides, prosecution happens only when the aggrieved party is influential or powerful.,The findings of this research give a strong insight into the social media behaviour of users in relation to hate contents/posts. The study establishes the fact that Indian people are in favour of free speech, but with a sense of restraint and responsibility. The work could form the basis for future research on various aspects of hate speech on social media. Researchers could study the trials and prosecutions that have happened over the past few years and whether punishment has acted as a deterrent.,The research is likely to be important for those involved in work on freedom of speech or hate speech through social media. Social networking sites such as Facebook would also get some insights into users’ perception towards free and hate speech mechanism on social media. (shrink)

This Editorial introduces the thematic series on 'Toward a New Psychiatry: Philosophical and Ethical Issues in Classification, Diagnosis and Care' http://www.biomedcentral.com/series/newpsychiatry.

This study looks at how discourses of corruption in Bangladesh are discursively constructed within the official documents of Transparency International (TI), a non-profit organization that monitors corruption worldwide. It explores how an orientalist notion regarding Bangladesh is appropriated in neoliberal global discourse through TI’s corruption surveillance process. A postcolonial analysis of TI’s publications demonstrates a symbiotic relation between orientalism and neoliberalism. TI sets up a binary of ‘corrupt’ global South vs. ‘clean’ global North, reinforcing the uneven power relations between nation-states (...) that can be seen as a neocolonial move for maintaining Western hegemony and enabling neoliberal ideology over non-Western territories. Philosophy and Progress, Vol#67-68; No#1-2; Jan-Dec 2020 P 49-76. (shrink)

This paper provides a synopsis of the human rights enforcement in Bangladesh, which marks its 50 years in 2021 since its independence. After a theoretical background on how human rights are perceived as legal and political instruments, it critically discusses human rights provisions and explores the legal and institutional frameworks on human rights enforcement in Bangladesh—(re)construed in 50 years (1971–2021). Finally, it divulges the controversies in human rights enforcement and a roadmap to address them by making some suggestions: multiple legislative, (...) administrative, and judicial reforms are required to tackle human rights abuses to ensure punishment for the abusers and restitution for the victims. The paper concludes with the notion that the positive will of the relevant stakeholders (legislature, executive, and judiciary) is the key to upholding and protecting the human rights of Bangladeshi citizens. The significance of this paper lies in exploring the complexities associated with the laws and insular national politics, which often debars the enforcement of human rights and crucially compromises Bangladesh’s ability to empower its citizens. (shrink)

The formative stage of Cao Dai religion is closely connected to Vietnamese traditional myths, tales, doctrines and practices that are mostly transmitted orally down to the centuries. At the same time, Caodaism constantly maintained its links with religio-cultural elements of Chinese, Indian and Western origin. Due to this fact, Caodaism, with its synthesis of Eastern, Southeast Asian, Indian and Western elements specially from indigenous folk tales, Buddhism, Hinduism, Taoism, Confucianism, and Christianity, appeared as the religion of an acclaimed small group (...) in 1926. This paper aims to examine how Caodaism evolved by a long-term process of Western and Asian acculturation. Thus, first to be considered is the significant role of socio- historical factors in creating a strong footing for the progress of Caodaism in Vietnam at the beginning of the early 20th century. Second, the process of Vietnamese acculturation is taken into consideration through which Caodaism borrowed diverse elements from different resources around it. Methodologically, a critical discourse analysis is adopted to consider the characteristics of Caodaism and its sociohistorical structure that is required to understand its historical origin and development. In conclusion, first, the study clearly demonstrates the close connection between Caodaism and the major factors of acculturation such as integration and assimilation for its development and diffusion around the South of Vietnam. Second, the current problem demands a careful consideration of some other crucial factors that might have influenced the rise and progress of Caodaism since its official journey in 1926. Philosophy and Progress, Vol#73-74; No#1-2; Jan-Dec 2023 P 21-36. (shrink)

Information on the current prevalence and types of consanguineous marriages in Malakand District, Khyber Pakhtunkhwa Province (KPK), Pakistan, was collected from 1192 rural couples. Some 66.4% of marriages were between couples related as second cousins or closer (F≥0.0156), equivalent to a mean coefficient of inbreeding (α) of 0.0338. The data suggest that the prevalence of consanguineous unions in Malakand has been increasing during the last decade, in response to the high levels of violence across KPK.

In philosophy happiness occupies a dominant position. From the beginning of philosophy, we find the scholarly engagement of philosophers in search of happiness for human being. It is actually a perennial search of mankind throughout history. My attempt in this paper is to become a part of that august journey. I will try to focus some points in my paper. At first, I will try to give an analytic presentation about the nature of happiness with references to different philosophers and (...) philosophical schools. In this part I will attempt to find out the root causes of the changing patterns of happiness by maintaining a chronological order. In the next part I will try to depict some significant debates regarding the pursuit of happiness. The question of enigma and reality will be dealt here in a comparative fashion. And finally, I will try to give some recommendations and suggestions for a happy life.As this is a qualitative work, here I confine myself within some relevant textbooks of philosophy and recent research articles on the pursuit of happiness. Content analysis, comparative discussion with a critical outlook and philosophical speculation will be within the research methodology of the paper. Philosophy and Progress, Vol#71-72; No#1-2; Jan-Dec 2022 P 129-151. (shrink)

Terrorism is a global phenomenon that constantly challenges human survival. Based on the social structure, human beings adopt different strategies to overcome its negative consequences on their mind and behavior. Coping strategies and those processes essential for adjustment and survival illustrate how individuals perceive, consider, deal with, and realize a stressful situation in the era of terrorism. The study focuses on exploring coping strategies and avoidance of terrorism impacts. This research study was qualitatively designed to explore the coping strategies adaptation (...) and their influence on the former FATA individuals during the wave of terrorism in the region. The study was undertaken in five districts of erstwhile FATA, including Dara Adam Khel, Orakzai Agency, Khyber Agency, and North and South Waziristan agency. A sample size of twenty-five (25) participants was purposively selected and interviewed, ten (10) focused group discussions (FGDs) were done from each district, and the other 50 participants were chosen for ten (10) FGDs. The collected data were analyzed via the thematic analysis technique. The findings revealed that coping strategies included four different phases: the welcome, resistance, acceptance, surrender, and flee phases for overcoming threats of terrorism. Furthermore, it was also found that fear of terrorism had strongly influenced the individuals’ physical, socio-economic, psychological, emotional stress and fear, education, and social integration. The study recommended that social integration and solidarity among the people, as well as their cooperation with the government, can eliminate the threat of terrorism. (shrink)

In this paper, we study bounded versions of some model-theoretic notions and results. We apply these results to the context of models of bounded arithmetic theories as well as some related complexity questions. As an example, we show that if the theory \(\rm S_2 ^1(PV)\) has bounded model companion then \(\rm NP=coNP\). We also study bounded versions of some other related notions such as Stone topology.

Textbooks play a strong part in constructing gender roles and status in society. Thus, the images, lessons, and stories of gender portrayed in textbooks affect the perception of prevalent masculine behavior. To develop an insight into the phenomena, this article analyzes the institutionalized patriarchy and patriarchal values embedded in the Urdu and English National Book Foundation textbooks for grades 5, 6, and 7. The study used content analysis techniques to decode the tone, juggling of meanings, pictorial representation, topic selection, word (...) selection, number of pages devoted to each topic, and gender placement of Urdu and Social Studies textbooks. The study explored whether women are portrayed as followers of men and men as having a leadership role. The mother is predominantly presented as a housewife who stays at home, cleaning and cooking all day. While the father goes to work every day and comes home and relaxes after a hard day’s work. Such placement of gendered roles has an effect on the thinking of young students and they internalize the idea that such roles are a natural part of their personality. Moreover, the books reflect a reality which is more male-oriented, while female representations are lacking in the dominant reality. (shrink)

Female entrepreneurship is steadily increasing around the world especially in developing countries where lack of job opportunities has forced people toward self-employment, Pakistan being no exception. Females in Pakistan are now actively participating in economic activities to get recognition of their abilities and to generate employment opportunities. Given the changing role of females over time, the study seeks the answer to a very important question i.e Are females in Pakistan are motivated towards self-employment then being employed if yes then what (...) is the magnitude and areas/sectors they are mainly engaged in? Specifically, this study aims to analyze the magnitude of the female-headed household enterprises in Pakistan by sector province, and region. In addition study evaluates the socio-economic background influencing their decision to own and operate household enterprise – or becoming self-employed. For, the assessment purpose study has used cross-sectional data of the PSLM/HIES for the period 2018-2019. Finings indicates that the majority of self-employed females in Pakistan are engaged in small-medium enterprises. Province wise break up shows, Punjab has the most female-owned household enterprises. The present study is unique in the sense that sector-wise magnitude by province and region for female entrepreneurs has not been comprehensively documented earlier. (shrink)

Innovation ecosystems are formed by interconnected firms that coalesce in interdependent networks to jointly create value. Such ecosystems rely on the norm of reciprocity—the give-and-take ethos of sharing knowledge-based resources. It is well established that an ecosystem firm can increase its competitive advantage by increasing interconnectedness with partners. However, much research has focused heavily on the positive role of inbound openness or ‘taking’ resources from ecosystem partners. The positive role of outbound openness or ‘giving’ resources to ecosystem partners remained less (...) explored and often misunderstood as eroding competitive advantage. We address this gap by first developing a conceptual model about the mediating role of inbound openness and outbound openness in the relationship between a firm’s ecosystem interconnectedness and competitive advantage. We then test this model on a large sample (_n_ = 794 managers) from Silicon Valley (USA) and Macquarie Business Park (Australia). Results indicate that outbound openness is a more important mediator than inbound openness for ecosystem firms seeking competitive advantage. Our findings suggest that the effect of outbound openness goes beyond merely generating tit-for-tat reciprocity to generating strategic benefits in their own right. The study adds to knowledge about the ethics of innovation ecosystems by showing that outbound openness to partners improves competitive advantage. Ecosystem firms, thus, do well by doing good when they increase their outbound openness. (shrink)

While a corporate ethics program is expected to reduce employees’ unethical behavior, understanding the effects of the ethics program elements on reducing the unethical behavior is a crucial issue. This study aims to explore how a corporate ethics program with multiple control elements, including punishment, monitoring, internal reporting, code of ethics, ethics support service and ethics training, influence employees’ threat appraisal process, coping appraisal process and unethical behavior at workplaces. The data to verify proposed research hypotheses were collected by administering (...) questionnaire survey on four autonomous government organizations in Bangladesh. Research findings show that only punishment and monitoring have significantly negative relationships with unethical behavior. Monitoring and internal reporting have significantly positive relationships with threat appraisal. The code of ethics, ethics support service and ethics training are associated positively with coping appraisal. The mediation results reveal that coping appraisal mediates the relationship between ethics program elements and unethical behavior; but the mediation effects of threat appraisal are not significant. This study provides valuable insights into how a corporate ethics program with multiple control elements reduces employees’ unethical behavior as well as how employees’ threat and coping appraisal processes are related to the corporate ethics program and unethical behavior in organizations. (shrink)

The COVID-19 pandemic has had a substantial impact on the retail industry around the globe, including in the vast market of India. The response to the pandemic required stores to close and develop new ways to approach shoppers more efficiently. The worldwide usage of social media enabled the growth of social commerce. Influencers on s-commerce platforms use live broadcasting on their channels to promote endorsed products. The features of s-commerce influencers enhance users' trust in the online community and s-commerce intention, (...) impacting their online purchasing intentions. In this study, we collected data from 379 Indian consumers to test the measurement and structural model using Partial Least Square-Structural Equation Modeling to verify our conceptual framework. We found that trust in the online community and s-commerce intention are antecedents of online purchase intentions. Additionally, the results demonstrate that trust in Indian social media influencers and s-commerce intentions are vital for boosting consumers' purchase intention, verifying the hypothesized mediating effect of these factors. Based on these results, we suggest several managerial actions that could enhance the value of s-commerce for franchises, executives, e-retailers, and e-marketplaces. (shrink)

The main objective of this study is to assess the state of business ethics in New Zealand organisations. The survey results suggest that top New Zealand companies give low priorities to ethical values. A number of suggestions have been put forward by the respondents to improve the corporate ethical environment. These include commitment of top management, written and published codes of ethics, comprehensive accounting standards and annual reporting and monitoring and an efficient legal and education system.

Philanthropy plays a significant role in developing and promoting education over the world. The motives of philanthropy have been studied by designing different scales, most of which are based on the behavior of non-philanthropists, some scales even contain reverse answers for which complexity arises in calculating the scores, there have been limited studies on the educational philanthropic scale too. Danobir Dr. Syed Ragib Ali is one of the renowned philanthropists in Bangladesh, there are a good number of studies on his (...) philanthropic contribution but very few of them focused on the level of educational philanthropy of Dr. Ali. This study aims to critically revisit the existing philanthropic scales so far to design an educational philanthropic scale and assess the level of educational philanthropy of Danobir Dr. Syed Ragib Ali using the newly formed scale. After carefully reviewing the literature, the study initially designed a 35-item ‘Educational Philanthropic Scale (EPS)’ and conducted a purposive online survey among 400 different levels of educational entrepreneurs in Bangladesh. Then, an exploratory factor analysis was conducted from the usable 317 responses and finally, a 27-item scale was prepared. The Cronbach’s Alpha has been tested for reliability and the Kaiser-Meyer-Olkin (KMO) calculated for sampling adequacy. By using this scale it is found that Danobir Dr. Syed Ragib Ali is an exceptionally educational philanthropist. The findings of this study significantly contribute to the existing literature and can broadly be used to assess the educational philanthropic levels within individuals and organizations. The future researcher can find a new horizon to update the scale. (shrink)

Informed consent to medical intervention is fundamental in both ethics and law. But in practice it is often not taken seriously in developing countries. This paper provides an appraisal of informed consent practices in Bangladesh. Following a review of the ethical and legal principles of informed consent, it assesses the degree to which doctors adhere to it in Bangladesh. Based on findings of non-compliance, it then investigates the reasons for such non-compliance through an appraisal of informed consent practices in Bangladesh (...) and provides recommendations aimed at improving such practices. The significance of this paper lies in unveiling the interdependence between the ethical and legal traits of informed consent and their ramifications on strengthening the patient-oriented approach of duty to care. (shrink)

The epistemological foundation of unity of knowledge is used to formulate a system-model of participatory socioeconomic development. The micro-properties of such a participatory development approach are deeply ethical in nature. In order to bring out the endogenous role of ethics derived from the moral law in reference to the epistemic foundation, and thereby explain their impact on the socioeconomic development experience, the methods of topological space and topological mappings are found to be appropriate for formalizing the complex nature of participatory (...) dynamics. They emerge in the midst of institutional and organic interaction, integration, and evolution. The application of topological methods to participatory socioeconomic development thus opens up a field that is rarely used by mathematical economists. In this sense this article is an original contribution to the area of ethical development theory and its topological explanation and application. (shrink)

Three distinct models of political economy are articulated in this article to chart out the possible politico-economic futures of the Arab World. Of these, the present predicaments of the revolutionizing Arab populace are argued to have been caused by the continuance of the wrong social choices. It depended for a long time now on the alienating model of differentiation and alienation of the Arab nations by their rulers, and by their uncritical immersing in the equally debilitating globalization agenda. Two models (...) of the alienating and unfeasible types are formulated as the prevailing ones today. The arguments and empirical study of limited socioeconomic data with the examples of Egypt, Tunisia and Yemen, which are considered as exemplary of the revolutionary Arab World, point out that social factors based on the demand for participation and representation, self-reliant social change, and opportunities are the overwhelming factors of politico-economic change. These factors, as opposed to the purely economic factors, must be embedded in a synergistic way with the rest in a distinctive future model of Arab political economy. Three formal models of possible political economy of the future Arab World with their evolutionary futures are formalized. Necessary social and policy implications are drawn in reference to these three evolutionary Arab futures in political economy. (shrink)

In this article, we make analysis of the implicit fractional differential equations involving integral boundary conditions associated with Stieltjes integral and its corresponding coupled system. We use some sufficient conditions to achieve the existence and uniqueness results for the given problems by applying the Banach contraction principle, Schaefer’s fixed point theorem, and Leray–Schauder result of the cone type. Moreover, we present different kinds of stability such as Hyers–Ulam stability, generalized Hyers–Ulam stability, Hyers–Ulam–Rassias stability, and generalized Hyers–Ulam–Rassias stability by using the (...) classical technique of functional analysis. At the end, the results are verified with the help of examples. (shrink)

In the field of teaching English to speakers of other languages (TESOL), much empirical research has investigated learner and teacher autonomy, agency, and identity. Yet, little prior research has...

Cet article propose d’étudier différentes commissions municipales de la vie nocturne à Lille. Depuis les années 2000, ces instances de concertation ont essaimé en France et dans d’autres États européens dans le but d’encadrer le déploiement d’une économie de la fête nocturne. À partir d’une enquête monographique menée depuis 2012, reposant sur des entretiens avec des professionnels de la nuit et des différentes institutions concernées (mairie, préfecture, police), des observations ethnographiques de ces commissions, et une analyse des archives municipales, nous (...) nous proposons d’esquisser une généalogie de ces instances de concertation en mettant de côté la recherche de ses effets sur l’action publique au profit de l’étude de ses usages et _in_ _fine_ de ses fonctions latentes. Notre perspective diachronique nous permet de tester l’hypothèse éliassienne d’une forme de « curialisation » de la vie nocturne. Ces espaces de délibération constituent un moyen pour la mairie de prendre pied dan... (shrink)

Relation between physicians and pharmaceutical industry is required for the benefit of the patient. But it may turn into business and overthrow the patients’ benefit. The relation might be in question at present and in future. Several questions are flowing in Bangladesh. To solve these queries we have explored the situation in developed and developing countries. The physicians and associations of pharmaceutical industries developed several ethical guidelines in those countries. They have addressed the long lasting issues on gift provided to (...) physician, cash back, sample, industry sponsored scientific meetings, research and hospitality. There are huge restrictions to ensure the right of the patient’s e.g. limitation of inexpensive gift by the pharmaceuticals, avoiding expensive medicine instead of equally effective low priced medicine. We are lacking behind to protect the patient right properly: regulation, adherence to existing guide line, lack of guidance from statutory bodies. The current scenario is far behind the right of patient. In Bangladesh it is not yet addressed either by professionals or by pharmaceutical associations. It is the immediate need to construct a guide line for physicians and pharmaceutical industry of Bangladesh.Bangladesh Journal of Bioethics 2015 Vol.6 (1):1-5. (shrink)

This study examines whether mortality of two adjacent siblings in families is age-specific and is modified by the MCH78, 198590 in the treatment (MCH–FP) and comparison areas. Logistic regression was used to estimate the net effects of survival status of elder siblings on mortality of younger siblings in the neonatal, postneonatal and toddler periods, controlling for birth order, previous birth interval, maternal age, education and religion, household possession of valuable items and sex of the child.

The convergence of corporate social responsibility (CSR) and corporate governance (CG) has changed the corporate accountability mechanism. This has developed a socially responsible ‘corporate self-regulation’, a synthesis of governance and responsibility in the companies of strong economies. However, unlike in the strong economies, this convergence has not been visible in the companies of weak economies, where the civil society groups are unorganised, regulatory agencies are either ineffective or corrupt and the media and non-governmental organisations do not mirror the corporate conscience. (...) Using the case of Bangladesh, this article investigates the convergence between CSR and CG in the self-regulation of companies in a less vigilant environment. (shrink)

Management and business literature affirm the role played by stakeholders in corporate social responsibility practices as crucial, but what constitutes a true business–society partnership remains relatively unexplored. This paper aims to improve scholarly and management understanding beyond the usual managers’ perceptions on salience attributes, to include how stakeholders can acquire missing attributes to inform a meaningful partnership. In doing this, a model is proposed which conceptualises CSR practices and outcomes within the frameworks of stakeholder salience via empowerment, sustainable corporate social (...) performances and partnership quality. A holistic discussion leads to generation of propositions on stakeholder salience management, corporate social performance, corporate–community partnership systems and CSR practices, which have both academic and management implications. (shrink)

This essay situates Foucault`s ideas of ‘biopower’ and ‘governmentality’ within the Indian context of the Covid emergency, analysing how the excesses of ‘biopolitical’ and the authoritarian forms of ‘governmentality’ evoke a radical re-reading of Foucault within Covid-infested India. We argue how pre-existing ‘discursive’ conditions of biomedical, digital, and neoliberal India facilitated more majoritarian and undemocratic forms of (bio)politics during the Indian experience of the pandemic, exposing the migrant workers in particular to tremendous ‘precarity’ and turning them into pandemicariat. To meet (...) our theoretical ends, we investigate through forging links between Foucauldian theory – consisting of a set of concepts like biopolitics, anatomo-politics, governmentality etc— and ideas like transmuted biosociality, truncated sociality, will to live, pandemicariat etc. Current conditions of truncated sociality render human bodies more ‘discursively’ available for ‘biomedical’ and ‘biopolitical’ interventions, disempowering people’s capacity to sustain the more synthetic biosocial substances of conviviality. However, following Agamben’s early controversial stance for braving the virus, we would like to envisage “life” to be more than “survival” alone. We would also argue that the hard times of the pandemic invoke a new grammar of the “will to live” that was practised by the pandemicariat against heavy odds. (shrink)

The notion of neutrosophic cubic set is originated from the hybridization of the concept of neutrosophic set and interval valued neutrosophic set. We define similarity measure for neutrosophic cubic sets and prove some of its basic properties. We present a new multi criteria group decision making method with linguistic variables in neutrosophic cubic set environment. Finally, we present a numerical example to demonstrate the usefulness and applicability of the proposed method.

Credible and well-functioning governance is crucial for the value creation of firms. Recently, private sectors have undergone substantial changes by focusing on good governance as a tool to enhance value, reputation, and image. The primary features of firms with good governance include greater emphasis on accountability practices, proper implementation of a corporate integrity system, and sound internal controls in place to avoid risk and to ensure policy and procedures that are complied. Government linked companies (GLCs) as the backbone of the (...) Malaysian Government have been harshly criticised for not being able to create value(s) despite receiving high priority in the process of getting government projects. Therefore, this study aims to examine the role of good governance systems, which are reflected through accountability systems, corporate integrity systems, and internal control systems towards value creation of Malaysian GLCs. This study collected primary data based on a set of questionnaire survey among 100 GLCs in Malaysia. Based on the regression analysis, this study found that corporate integrity systems and internal control systems were vital elements in ensuring value creation in GLCs. (shrink)

Caffeine, a known CNS stimulant is given as an adjunct component in most abused drugs which could be fatal with repeated administration in many circumstances. This paper presents a study to investigate the effect of repeated administration of caffeine at high dose on rat liver, and discusses ethical and policy issues of caffeine use. Long Evans rats were treated with pure caffeine solution in distilled water through intragastric route once daily for consecutive 56 days. Three groups of rats recognized as (...) low dose, high dose and control group received 6mg caffeine / kg BW, 12mg caffeine / kg BW and distilled water, respectively. Rat plasma was examined for liver transaminases and alkaline phosphatases concentrations which were significantly increased in plasma as compared to the control. Both rat plasma and liver homogenate were subjected to estimate malondialdehyde, advanced oxidation protein product, nitric oxide, antioxidant enzyme catalase, glutathione and superoxide dismutase activity. MDA, AOPP, NO levels increased and SOD activity decreased significantly in both plasma and liver as compared to those of control where as CAT and GSH activity remain unchanged. Rat liver tissues were studied histochemically with Hematoxylin and Eosin, and Picro Sirius Red staining. Significantly increased infiltration of inflammatory cells and progressive deposition of collagen fibre were visible in liver tissue of caffeine treated both dose groups as compared to the control. Long term administration of caffeine at higher dose, significantly contributes to liver inflammation and consequent fibrogenesis. This raises significant ethical and policy issues. (shrink)

The scientific methodology underlying model-building is critically investigated. The modeling views of Popper and Samuelson and their prototypes are critically examined in the light of the theme of the moral law of unity of knowledge and unity of the world-system configured by the meta-epistemology of organic unity of knowledge. Upon such critical examination of received methodology of model-building in economics, the extended perspective?namely of integrating the moral law derived from the divine roots as the meta-epistemology?is rigorously studied. The example of (...) the Islamic prerogative in interpreting the holistic world-system through model-building in economics is highlighted. A religio-philosophical approach is adopted to exemplify some approaches in Islamic model-building. An especial focus is placed here on grassroots types of financing and activities. The critique of these models within the existing Islamic scholarship is carried out. The result is new dimensions of macroeconomic analysis that emanate in a logical way from the meta-epistemological approach, and oppose the mainstream ideas, both in received and Islamic economic thinking as of now. (shrink)