The origin of marine invertebrate larvae has been an area of controversy in developmental evolution for over a century. Here, we address the question of whether a pelagic “larval” or benthic “adult” morphology originated first in metazoan lineages by testing the hypothesis that particular gene co-option patterns will be associated with the origin of feeding, indirect developing larval forms. Empirical evidence bearing on this hypothesis is derivable from gene expression studies of the sea urchin larval gut of two closely related (...) but differently developing congenerics, Heliocidaris tuberculata (feeding indirect-developing larva) and H. erythrogramma (nonfeeding direct developer), given two subsidiary hypotheses. (1) If larval gut gene expression in H. tuberculata was co-opted from an ancestral adult expression pattern, then the gut expression pattern will remain in adult H. erythrogramma despite its direct development. (2) Genes expressed in the larval gut of H. tuberculata will not have a coordinated expression pattern in H. erythrogramma larvae due to loss of a functional gut. Five structural genes expressed in the invaginating archenteron of H. tuberculata during gastrulation exhibit substantially different expression patterns in H. erythrogramma with only one remaining endoderm specific. Expression of these genes in the adult of H. erythrogramma and larval gut of H. tuberculata, but not in H. erythrogramma larval endoderm, supports the hypothesis that they first played roles in the formation of adult structures and were subsequently recruited into larval ontogeny during the origin and evolution of feeding planktotrophic deuterostome larvae. (shrink)

This study identified the influences of maternal socio-demographic and antenatal factors on stillbirths and neonatal deaths in New South Wales, Australia. Bivariate and multivariate analyses were used to explore the association of selected antenatal and maternal characteristics with stillbirths and neonatal deaths. The findings of this study showed that stillbirths and neonatal deaths significantly varied by infant sex, maternal age, Aboriginality, maternal country of birth, socioeconomic status, parity, maternal smoking behaviour during pregnancy, maternal diabetes mellitus, maternal hypertension, antenatal care, plurality (...) of birth, low birth weight, place of birth, delivery type, maternal deaths and small gestational age. First-born infants, twins and infants born to teenage mothers, Aboriginal mothers, those who smoked during the pregnancy and those of lower socioeconomic status were at increased risk of stillbirths and neonatal deaths. The most common causes of stillbirths were conditions originating in the perinatal period: intrauterine hypoxia and asphyxia. Congenital malformations, including deformities and chromosomal abnormalities, and disorders related to slow fetal growth, short gestation and low birth weight were the most common causes of neonatal deaths. The findings indicate that very low birth weight (less than 2000 g) contributed 75·6% of the population-attributable risks to stillbirths and 59·4% to neonatal deaths. Low gestational age (less than 32 weeks) accounted for 77·7% of stillbirths and 87·9% of neonatal deaths. The findings of this study suggest that in order to reduce stillbirths and neonatal deaths, it is essential to include strategies to predict and prevent prematurity and low birth weight, and that there is a need to focus on anti-smoking campaigns during pregnancy, optimizing antenatal care and other healthcare programmes targeted at the socially disadvantaged populations identified in this study. (shrink)

Since the inception of the Pastoral Care Movement, the approach to pastoral care has evolved from the traditional shepherd model to a more clinical, client-centred method. This evolution requires a thorough analysis of recent trends and dynamics in pastoral care, especially in relation to key theological theories and the Church’s role in providing support. Today, the landscape of pastoral care covers a range of topics, including ecotheology, global existential crises and the Church’s involvement in addressing these issues. Additionally, this examination (...) reveals conclusions about theological shortcomings and inconsistencies in emphasis within pastoral care.Contribution: This article provides a critical overview of pastoral care in its current form and context, examining its relevance to the existential needs of the postmodern social milieu and its role in the church today. It offers a critical evaluation of pastoral care within contemporary culture. (shrink)

ch. 1. Ocherki teorii intelligent︠s︡ii -- ch. 2. Ocherki istorii russkoĭ intelligent︠s︡ii.

This is a clear assessment of Hume's theories of the self and personal identity, including his famous Treatise on Human Nature . Pitson provides a critical exploration of his thinking, also examining the continuing relevance of Hume's theories for contemporary philosophy and relating it to his broader reflections on human nature itself. Divided into two parts, Pitson's study follows Hume's important distinction between two aspects of personal identity: the "mental" and the "agency". The first part discusses Hume's conception of the (...) mind as a "bundle" or "system" of perceptions and explores Hume's position on the traditional mind/body problem. In the second part Pitson examines a range of topics including Hume's treatment of character, the relationship between human and animal nature, and the nature of agency. (shrink)

In this paper I hope to show that Geach misunderstands the nature of Plato's argument in the Euthyphro and more importantly the reasoning behind the dialectical strategy adopted by Socrates. Furthermore I shall argue that Geach's reading of the Euthyphro engenders serious difficulties, that stand in the way of understanding the manner in which Plato construes the problem of determining the nature of, and relationship between universal and particulars, which is of great significance because it is precisely this problem, in (...) relation to piety, that is central to the Euthyphro. In the appendix I shall sketch the outline of an argument in order to justify the assumption that the theory of Forms is present in the Euthyphro. (shrink)

Both the author and the date of this five-volume poem, the first Western document to link the houses of the zodiac with the course of human affairs, are uncertain. The author's name may be Marcus Manilius, or Manlius, or Mallius, and the latest datable event mentioned in the books themselves is the disastrous defeat of Varus' Roman legions by the German tribes in 9 CE. The writing shows knowledge of the work of Lucretius, but the work is not referred to (...) by any subsequent writer, suggesting that it was never widely disseminated. A manuscript was rediscovered by Poggio Bracciolini in 1416 or 1417, and editions were produced by Scaliger and Bentley, but this immensely erudite edition of 1903–1930 by the scholar and poet A. E. Housman is regarded as authoritative. Volume 4 describes the influence of the zodiacal signs on the people born under them. (shrink)

More than simply a listing and abstract discussion of ideas, the book presents a searching analysis of Aristotle's thought, both in terms of its historical ...

This paper explores the underrepresentation of women and minorities in academic philosophy. Specifically, it focuses on why, given the relatively even male/female ratio at undergraduate level, women are underrepresented at every level above this. It addresses some of the misconceptions and myths surrounding women in philosophy, including those surrounding the discussion of the different‐intuition hypothesis. It also explores the ways in which feminist research in philosophy is subject to marginalisation as a result of systematic exclusionary practices typical of the dominant (...) culture of justification within traditional philosophy. It argues for the necessity of an intersectional approach, and the importance of taking seriously the psychological and sociological analysis of underrepresentation, in order to improve both the experience and the representation of women and other minorities at all levels of professional philosophy, as well as of the discipline as a whole. (shrink)