In this article we are offering a method of analysis and formalization of the Epicurean objection to the Skeptics from the Adversus mathematicos VIII, 337, 6-9. We emphasize the importance of this objection for understanding Sextus Empiricus’ response to it, continuously discussed by the historians of philosophy. The Epicureans argue that the Skeptics cannot criticize their proof, because when the Skeptics are criticizing their proof, they think something different from the original proof, so that the original proof remains untouchable by (...) any criticism. We explain in which sense the holistic assumption used by Sextus Empiricus and some philosophers before him can be used in the Epicurean objection to the Skeptics. In the final formalization we show that Epicureans’ argument can be interpreted as logically correct and deduced from sound premises. In the course of arguing for this thesis we are using the technical means of contemporary epistemic logic. (shrink)

: I reformulate and elaborate on important claims relevantly put for debate by the commentators, i.e., counterfactuals are a form of observable experience rather than a plurality of ….

Multidrug resistance (MDR) is developed in a population of somatic mammalian cells in vivo or in vitro when they are selected for resistance to each of a large group of drugs (colchicine, adriamycin, actinomycin D, etc.). It is produced by the amplification of some unknown gene(s) whose product(s) evidently change(s) the plasma membrane permeability of a cell to a selective agent and to other unrelated compounds. A large specific genomic region (150–250 kbp) undergoes amplification in MDR cells selected for the (...) resistance to different drugs. Amplified DNA is located in homogeneously staining regions of chromosomes, double minute chromosomes and small chromatin bodies – episome‐like structures that replicate out of the S‐phase of a cell cycle. The selection of MDR cell variants is accompanied by regular karyotypic evolution specific for this type of drug resistance. (shrink)

The article offers a logical reconstruction of Marx's theory of history. On the basis of an analysis of the concept of labor, the author presents and discusses the four main socioeconomic formations of human history. The author challenges the Marxian project of the elimination of both division of labor and private property pointing to its theoretical and practical shortcomings.

Racism cannot be ousted by external social manipulations without philosophical reflection on distinguishing between the structure of this phenomenon and the possibilities of its cultural overcoming. This essay analyzes Russian traveler Nicolai Miklouho-Maclay’s heroic struggle against racism. His nap on the outskirts of a Papuan village is presented as an existential act of throwing off any objectivities of one’s personal “I” in an effort to overcome racist insanity using a universal dialogue between accepting each other as equals. As a xenophobic (...) obstacle to a dialogue with the Other, racism generates a global demarcation of humanity that passes through the subjective core of each person’s identity. It is this subjectivity that should be brought to its utmost flexibility for the sake of a dialogue with the Other. The vanishing objectivity of the “I,” according to Karl Jaspers, can be defined as energeticism. It is the strife for achieving the universal “I” which is indefinite but still IS there. (shrink)

The article discusses whether there is an equivalent of the concept of "reflexion" in the philosophy of India as developed independently of the European one. The author comes to the conclusion that there is none. The concept of reflexion is unique to the West. If it does not exist in Indian thought, is it possible to find Indian examples of what a European or Russian philosopher would call reflexion, the application of reflexion? How homogeneous are they and how highly valued (...) are they in the Indian tradition? It turns out that examples of Indian reflexivity are very diverse and are found in such areas as reflexivity in reasoning, reflexivity of mental processes, reflexive closure of epistemology to ontology, and, finally, in the fact that the limit of reflexivity, which can be realized by a thinkeras a metaphysical practitioner, is nothing but the inadequately formulated liberation by Europeans as an "Indian religious ideal". (shrink)

This article, written by a Russian cultural historian, analyzes the concept of "ideology" in the work of Clifford Geertz. and his role in understanding the figurative nature of ideology as a cultural system. The author compares Geertz's semiotic approach to culture with thesemiotics of culture developed by Russian theorists, particularly Yuri Lotman, showing the convergence and divergence of the two differentnational traditions. This understanding of the nature and functions of ideology opens new possibilities for discussing the tortured relations of ideology (...) and literature, showing the way fiction can affect the formation of ideological systems and influence practical politics. The analysis is illustrated by examples from Russian political life of the 1990s, when revolutionary changes demanded new sets of ideological metaphors that in their turn shaped the direction of events. (shrink)

This study provides a critical examination of biopolitics and the process of the subjectification of Russia, Ukraine, Georgia, and Estonia. The authors analyze multiple overlapping regimes of belonging, performativity, and debordering.

Context: Linguists and philosophers, as well as psychologists, have not yet offered a coherent explanation of the logic behind the intricate grammar of counterfactuals, the meaning of irreality and….

The construct of moral intensity, proposed by Jones (1991), was used to predict the extent to which individuals were able to recognize moral issues. We tested for the effects of the six dimensions of moral intensity: social consensus, proximity, concentration of effect, probability of effect, temporal immediacy and magnitude of consequences. A scenario-based study, conducted among business individuals in Singapore, revealed that social consensus and magnitude of consequences influenced the recognition of moral issues. The study provided evidence for the effects (...) of temporal immediacy. There was marginal support for the impact of proximity and probability of effect but no evidence that concentration of effect influenced recognition of moral issues. The paper concludes with a discussion of the implications of these results for researchers and organisational practitioners. (shrink)

A sociedade brasileira no que diz respeito a sua estrutura de relações sociais como conhecemos, tem início no Brasil colônia a qual a instituição de maior força era a escravagista. Nesse sentido, as formações e interações de classes da sociedade brasileira foram arregimentadas pelo racismo, sendo ele escancarado no passado, com leis e naturalização das práticas de disciminação racial, e mantendo grande influência atualmente com a utilização de “máscaras” que encontram para legitimar sua atuação na sociedade contemporânea. Nesse contexto, nos (...) últimos anos tem-se observado a atuação irregular de ações policiais no país, principalmente nas comunidades periféricas, sendo utilizada a brutalidade e a violência física e moral dos sujeitos, violando direitos humanos e fundamentais, e colocando em perigo a vida de crianças e adolescentes que residem nesses ambientes, sobretudo, as negras, reconhecendo assim a existência do racismo estrutural. Considerando que o país é democrático, e reconhecendo que os atores sociais possuem a capacidade de influenciar nas mudanças e construções de políticas capazes de discutir os fundamentos da vida pública e social, esta proposta de pesquisa tem por objetivo refletir como a brutalidade policial afeta a confiança de crianças negras no Estado democrático por meio de instituições de segurança e proteção. Trata-se de uma pesquisa de revisão bibliográfica, qualitativa e descritiva. (shrink)

To ensure that listeners pay attention and do not habituate, emotionally intense vocalizations may be under evolutionary pressure to exploit processing biases in the auditory system by maximising t...

In this paper we prove general exact unprovability results that show how a threshold between provability and unprovability of a finite well-quasi-orderedness assertion of a combinatorial class is transformed by the sequence-construction, multiset-construction, cycle-construction and labeled-tree-construction. Provability proofs use the asymptotic pigeonhole principle, unprovability proofs use Weiermann-style compression techniques and results from analytic combinatorics.

Стаття присвячена аналізу складного і суперечливого процесу демократизації арабського суспільства, який відбувається вже багато років. Сучасні глобалізаційні процеси торкнулися і арабського світу, де спостерігається зіткнення цивілізаційних парадигм. Разом з тим наголошується, що існуючі соціальні конфлікти та елементи суспільно-політичної нестабільності, які торкнулися ряду арабських країн, частково є результатом західного впливу і нав'язування інститутів, не властивих арабської соціокультурної традиції. З іншого боку, всі ці феномени цілком можливо розглядати як етап своєрідної демократизації арабського соціуму, який потрібен як важлива складова відповідного процесу.

Introduction. The complexity of the modern world causes a person to be overloaded with information and a desire to automate and simplify all these processes. Such a reaction is a natural response of the psyche, which strives to prevent excessive stress. At the same time, this natural defensive reaction is manipulated by forces that have the ability to control information and pursue their own narrowly focused goals. This is how the phenomenon of information warfare appeared and developed. The purpose of (...) the study is to consider information as a way of negative impact in the context of modern information wars. Methods. The author uses an axiological approach that reveals the importance of studying war not only from a materialistic perspective, but also from a spiritual, value-based one; the method of systematization allows us to consider at first glance disparate phenomena and events as part of a single system; using the structural and functional method, the phenomenon of information is comprehensively studied and the key mechanisms of its influence on humans and society are pointed out. Scientific novelty of the research. The paper examines the features of information that allow it to be used both in a positive and negative direction. The author provides current data on information wars and analyzes the involvement of modern Russia in all these processes. Information warfare is considered from the standpoint of a predominantly axiological approach, while exploring the possibilities of the influence of new types of information warfare on the processes of changing value orientations and spiritual traditions. It also reveals the importance of the ideology of “Western values” in the context of information warfare, which represents a new stage in the long process of civilizational confrontation. Results. Information is studied as a philosophical category, its functions and other characteristics are highlighted. Various approaches to studying information warfare are presented. The distinctive features of information warfare as a type of new generation wars are highlighted. Special attention is paid to the disclosure of the axiology of information warfare, as well as ways to counter information aggression. Conclusions. A successful society in the 21st century should be able to use the latest technologies to preserve its uniqueness, identity, and national identity to counter the information wars of modernity. (shrink)

For a long time, leading European thinkers have denied systematic, theoretical and rational nature of Chinese traditional thinking, unpretentiously reading it as banal moralizing, not supported by any proper philosophical discourse. However, the habitual socioethical label conceals a much deeper problematic of strategic thinking. At its center, there is the question of choosing all sorts of strategies: from everyday life to special technical ones, from personal existential choice to fateful state decisions. The concept of a winning strategy is emblematized by (...) the dramatic plot of a deadly risk but under certain conditions with guaranteed happy end. The strategy of harmony, which is miraculous in its effectiveness, is proposed as a exemplary strategy. It allows you to “step on the tiger’s tail” with impunity. From the point of view of strategic thinking, the criterion of cognitive value of reasoning is its effectiveness, and the most effective is unmistakable prediction, i.e. the ability to predict the outcome of future developments with the help of reasoning. In the ideal case, prognostic reasoning becomes not just plausible but 100% reliable that is an apodictic true inference. Therefore, the highest cognitive status in the Chinese intellectual tradition is endowed with guaranteed error-free prognostic reasoning. This type of reasoning, where the reliability of foresight is guaranteed by the implementation of a certain winning strategy, can be called the prognostic form of deduction. As a result, the dynamism of Chinese logic, which relies on a deliberate staging of the future, is strikingly different from the static nature of the classical image of logic, where logic is no more than a static guardian of correctness of reasoning. On the contrary, the Chinese concept of logic focuses on deriving consequences from strategic considerations regarding the future, actively and purposefully shaped by the subject who at the same time constructing both himself and the world around him. (shrink)

Gene transcription in eukaryotes is associated with conformational changes of a large area of chromatin adjacent to a gene. This rearrangement may involve the whole loop (topological domain) to which a given gene belongs.Regulatory events associated with activation or inactivation of transcription are found to act through relatively short nucleotide sequences, often located several thousand base pairs apart from gene. These sequences, termed enhancers may act independently on their distance from or orientation with respect to the gene.Both long‐range conformational rearrangements (...) of chromatin and any long distance effects of enhancers may be associated with elastic torsional strain in DNA, arising in transcriptionally active chromatin loops. Enhancer effects, in particular, may be associated with conformational transitions in DNA competing for the energy deposited in the elastic spring of the DNA. (shrink)

The author argues that the idea of freedom guided Vygotsky’s research from his very first steps in psychology, when he was deliberating on the “overman” and on “mastering one’s own behavior” by mea...

The authors consider the phenomenon of overcoming and examines the culture of overcoming in Marxist dialectics. As the core thread for dealing with this issue in the writings of Karl Marx, the authors follows the research on the socio-biological problem carried out by Vladimir I. Plotnikov, a Russian representative of the Marxist dialectics. Examining Marx’s standpoint on the subject, Plotnikov provides an outline of the issue of overcoming. This issue is described as the issue of mankind overcoming its species’ boundaries (...) and divided into the problems of the first and second overcoming. The first overcoming is defined as breaking out beyond the boundaries of instinctual activity, while the second—as the problem of removing the self-restrictions by an alienated person. (shrink)

The purpose of the research is to identify the structure of investment projects in the regions included in the Northwestern Federal District on the basis of the data of the digital platform "Investment Projects". The scientific novelty consists in determining the sectoral structure of investments in the Northwestern Federal District, based on the forms of systematization of information used on this portal. The result of the study is the identification of industry specifics of each region and the selection of three (...) groups of regions based on the level of investment attractiveness. (shrink)

The article is devoted to the problem of time in modern science, where in recent years there have been major changes related to the latest discoveries in the field of the foundations of quantum theory. The author refers to works of K.-F. von Weizsacker (which works are not well-known in Russian-speaking field). Weizsacker deploys a large-scale program of building modern physics, while starting (not only as a physicist, but also a professional philosopher) with questions of philosophical interpretation of postulates of (...) modern physics, especially quantum mechanics. His key thesis is that time in physics is fundamentally distinct, which represents the whole physics as an integral scientific discipline. Weizsacker comes from physical and philosophical reflections, that give a special value to his work. Analyzing the conclusions of theoretical physics, namely the issues of substantiation of statistical mechanics, thermodynamics, and, above all, quantum mechanics, Weizsacker comes to the key idea of the structure of time in the substantiation of physical theory. The author in this conclusion disagrees with the opinion of most modern physicists that time has a subjective character, and the modus of the past, present and future reflects its essential character. The allocation of the time structure requires special logic. Such a logic is temporal and quantum. Starting from temporal logic, introducing the concept of possibility and probability, he comes to the substantiation of quantum mechanics. Being modal logic, it is based on the concept of possibility and probability. Key concept for Weizsacker is a binary alternative (Uralternative), closely related to the principle of superposition in quantum mechanics. By introducing the concept of certain alternatives, essentially actualized alternatives, Weizsacker shows how one can get the theory of relativity with its space-time structure. Further, he shows that based on its structure, you can get the theory of relativity. The space-time structure in this case is secondary, relational, as understood by Leibniz, Mach, and Einstein. (shrink)

The Cartesian cogito ergo sum is a major milestone for modern European philosophy, which shaped its mainstream for centuries. This dictum states that consciousness is the only reliable object of in...

The great disputants within the Islamic tradition, the Mutakallimūn, laid down the basis for rational discussion of causality by affirming the right of reason to engage in independent research. This affirmation could not be absolute; it took the form of a division of the spheres of competence belonging, respectively, to reason and Law. Reason was declared to be the judge in ontological and epistemological questions, whereas the sphere of ethics and legislation were left subject to religious Law. Certainly, this division (...) should not be understood too rigidly. The Mutakallimūn often remained loyal to the Law and did not permit reason to execute its rights to the full even when disputing ontological problems. On the other hand, in the sphere of legislation they asserted the rights of reason to define new norms, not established in Revelation, on the basis of rational analysis of revealed Law, thus defying the Zāhiriyya, “people of the manifest,” who denied the legitimacy of rational procedures for determining new norms of law. (shrink)

This article focuses on the views held by the early Bulgarian representative and interpreter of pragmatism Ivan Sarailiev on the two trends of this doctrine – the method for ascertaining meaning proposed by Charles Sanders Peirce, and the theory of truth propounded by William James. Sarailiev applied andpropagated the pragmatist ideas of the doctrine’s founders in Bulgaria in the 1920s, and is thus one of the first followers of Peirce in Europe and the very first in Eastern Europe. How deep (...) was Sarailiev’s understanding of the two types of pragmatism? How did they shape his philosophy and what was their role? This article will try to address these questions as well as presenting the overall reception of pragmatism in Bulgaria in the Interwar period through Sarailiev who was its only serious proponent both at the time and long aft erwards. (shrink)

The book deals with the influences exerted by Social Darwinism upon Korea’s modern ideologies and discourses in the 1880s-1900s. It argues that Social Darwinism constituted the main keystone for many pivotal discourses in early modern Korea, especially nationalism.

The authors of the volume under review proclaimed a “revisionist revolution” in Vygotsky studies. With the exception of the two chapters by Ekaterina Zavershneva, everything else in the book is written by Anton Yasnitsky—solo or in collaboration with René van der Veer, Eli Lamdan and Jennifer Fraser. It is demonstrated how the “Vygotsky cult” took shape and eventually spread throughout the world, and how the “myths” and “dogmas” of that cult are later subjected to deconstruction. The editors, van der Veer (...) and Yasnitsky, give an overview of Vygotsky’s published works and critically analyze editorial interventions in his texts, mainly in the six-volume Collected Works. The final chapter is devoted to the “birth of the cultural–historical Gestalt psychology,” focusing attention on the story of Vygotsky’s personal contacts with Gestalt psychologists. (shrink)

This article studies the phenomenon of overcoming and provides a rationale of the understanding of the totality of human experience that integrates the situation of overcoming as that of the transcendence of human existence. As the basis of the research we use an integrated model of archaic cultural overcoming of the life–death dichotomy—a metaphysics of overcoming. A result of this metaphysics is a specific dialectical ontology of myth, represented as an ontology of return. Manifestationism, holism, alogism, metamorphism, animism, cyclism, and (...) sacralism are the general principles of this ontology. Return ontologies are in conflict with the ontology and metaphysics of the finite present in the religious and scientific worldviews. The author sees the prospects for a further study of the phenomenon of overcoming in using the subjective energistic approach that leads to understanding the phenomenon of overcoming at the biosocial level. The results of the research can be used as a philosophical basis for the development of an archaeological activity theory, in particular, a unified integrated approach to the ancient burial ritualism. They also allow to deepen the theoretical concepts of man, society, and culture. (shrink)

The article focuses on two lecture courses - The Idea of time and The History of the Idea of Time - delivered by the French philosopher Henri Bergson at Collge de France in 1901-1903. While these courses cannot replace Bergsons published works for understanding his philosophy, they can shed new light on Bergsons popularity. Due to the requirements of the genre, Bergson presents his views in a most succinct and convincing manner and showcases his most original ideas. In these lectures (...) Bergson reinterprets traditional philosophical categories such as the absolute and the relative, the infinite and the finite, and explores two major modes of cognition - conceptual and intuitive knowledge. Major thrust of Bergsons arguments is targeted at conceptual cognition because it is incapable of grasping the duration. Conceptual cognition relies on signs to operate representations of reality. Bergson demonstrates that signs, including concepts, are general, fixating and they appeal to action. Conceptual cognition, therefore, is based on fragmenting continuous processes in reality. However, when discussing intuitive cognition Bergson provides but an outline by referring to intellectual sympathy, plunging into the thing in itself. Despite this apophatic description of the alternative - intuitive - mode of cognition Bergson insists on fundamental transformation of philosophy. We conclude that already in the early 1900s Bergson has in mind an entire project of reconstituting metaphysics and reorienting it towards the problem of time, what might be described as temporal turn in philosophy of the twentieth century. (shrink)