In the field of medically assisted reproduction (MAR), there is a growing emphasis on the importance of introducing new assisted reproductive technologies (ARTs) only after thorough preclinical safety research, including the use of animal models. At the same time, there is international support for the three R’s (replace, reduce, refine), and the European Union even aims at the full replacement of animals for research. The apparent tension between these two trends underlines the urgency of an explicit justification of (...) the use of animals for the development and preclinical testing of new ARTs. Considering that the use of animals remains necessary for specific forms of ART research and taking account of different views on the moral importance of helping people to have a genetically related child, we argue that, in principle, the importance of safety research as part of responsible innovation outweighs the limited infringement of animal wellbeing involved in ART research. (shrink)

Calorie restriction results in an increased lifespan and reduced fecundity of rodents. In a natural environment the availability of food will vary greatly. It is suggested that Darwinian fitness will be increased if animals cease breeding during periods of food deprivation and invest saved resources in maintenance of the adult body, or soma. This would increase the probability of producing viable offspring during an extended lifespan. The diversion of limited energy resources from breeding to maintenance of the soma is seen (...) as an evolutionary adaptation, fully compatible with the ‘disposable soma’ theory of the evolution of ageing. (shrink)

Political and legal theories of animal rights tend to raise the issue of domesticated animals’ sexuality and reproduction as a matter of population management and therefore concentrate too narrowly on providing justification for fertility restrictions. In this article, I argue that the normative logic underpinning the historical evolution and conceptual development of the fundamental right to health in international law, in its paradigm shift from population control to health rights, is consistent with initiating a similar transition in the (...) domesticated animal case. Without the relevant legal rights protections in place, individual interests in having control over, and making decisions about, their sexuality and reproduction get subordinated to the imperative of achieving sustainable population goals, resulting in the violation of bodily integrity and self-determination. What is missing from the present discussion of domesticated animals’ sexuality and reproduction is a rights-based discourse. I seek to address this gap in the literature by drawing on the existing human rights law norms to develop a conception of sexual and reproductive rights for domesticated animals as a shared yet differentiated fundamental right to health. I show that the realization of this right for domesticated animals is conditional upon a set of freedoms and entitlements, such as the freedom of choice, association, and mobility, as well as access to a range of health facilities, goods, and services. The aim is to introduce a new way of thinking about domesticated animals’ sexuality and reproduction as a rights and agency issue not just a population and fertility control dilemma. (shrink)

Wild animal reproduction poses an important moral problem for animal rights theorists. Many wild animals give birth to large numbers of uncared-for offspring, and thus child mortality rates are far higher in nature than they are among human beings. In light of this reproductive strategy – traditionally referred to as the ‘r-strategy’ – does concern for the interests of wild animals require us to intervene in nature? In this paper, I argue that animal rights theorists should (...) embrace fallibility-constrained interventionism: the view that intervention in nature is desirable but should be constrained by our ignorance of the inner workings of ecosystems. Though authors sometimes assume that large-scale intervention requires turning nature into an enormous zoo, I suggest an alternative. With sufficient research, a new form of gene editing called CRISPR promises to one day give us the capacity to intervene without perpetually interfering with wild animals’ liberties. (shrink)

In this volume Smith examines the early modern science of generation, which included the study of animal conception, heredity, and fetal development. Analyzing how it influenced the contemporary treatment of traditional philosophical questions, it also demonstrates how philosophical pre-suppositions about mechanism, substance, and cause informed the interpretations offered by those conducting empirical research on animal reproduction. Composed of essays written by an international team of leading scholars, the book offers a fresh perspective on some of the basic (...) problems in early modern philosophy. It also considers how these basic problems manifested themselves within an area of scientific inquiry that had not previously received much consideration by historians of philosophy. (shrink)

This paper explores ethical issues raised by the application of non-surgical, pharmaceutical fertility control to manage reproductive behaviors in domesticated and wild animal species. We focus on methods that interfere with the effects of GnRH, making animals infertile and significantly suppressing sexual behavior in both sexes. The paper is anchored by considering ethical issues raised by four diverse cases: the use of pharmaceutical fertility control in male slaughter pigs, domesticated stallions and mares, male companion dogs and female white-tailed deer. (...) Ethical concerns explored include animals’ welfare, the possible violation of animals’ rights, including rights to life, reproduction and bodily integrity; and potential concerns about loss of wildness. We compare ethical concerns about pharmaceutical fertility control with alternative strategies for managing animals’ reproductive behavior including spaying and neutering, sex separation, sex sorting, culling, and doing nothing. The paper concludes that there are some cases where pharmaceutical fertility control is the best ethical choice in current circumstances; but that there are other cases where alternative choices, including doing nothing, would be ethically preferable. This suggests that in ethical terms a case-by-case approach should be taken to the use of pharmaceutical fertility control in animals. (shrink)

In this Introduction, we present a collection of articles under the topic “the reproductive bodies of postgenomics.” Through individual and collective research, the articles explore—sociologically, ethnographically, and philosophically—how bioscience in the postgenomic age is changing our understanding of reproductive bodies, and more broadly, how it is challenging existing ideas of heredity, embodiment, kinship, and identity. Feminist and postcolonial theories of technoscience are at the heart of this collection, and our aim is to further biosocial thinking while being cognizant that practices (...) of postgenomics also continue to reproduce deterministic paradigms. The concepts of “knowledge,” “experience,” and “justice” form the reference points animating our investigations. We bring these concepts into conversation with one another to disentangle how postgenomics operate differently on the reproductive body, namely on the levels of practice, discourse, and norms. This is an important exercise as it will enable social science and humanities scholars to evaluate the political capacities of postgenomics for the future study of reproduction. (shrink)

Résumé Cet article s’intéresse au spectaculaire processus de transformation morphologique des animaux de rente qui s’est accompli en Europe occidentale de la fin du XVIIe siècle à la fin du XIXe siècle. Il met en évidence des stratégies, à la fois concurrentes et complémentaires, de transformation anthropique de l’animal d’élevage, mobilisant des acteurs, des institutions, des techniques et des compréhensions différenciées de la reproduction et de l’hérédité, en France et en Angleterre. Si la biopolitique d’État française diffère de (...) la libre entreprise des élites sociales rurales britanniques, les deux paradigmes convergent toutefois dans la production de discours et de pratiques visant à disqualifier les usages paysans en matière d’élevage et de reproduction animale. Pourtant, en dépit de leurs différences et de leurs succès initiaux, ces deux paradigmes zootechniques n’ont pas réussi – à la fin du XIXe siècle – à imposer l’intégralité de leur programme aux paysanneries. Par un surprenant retournement de situation, à la faveur de l’affirmation d’un mouvement de contestation intellectuelle et morale de la zootechnie, les paysanneries, dans leur diversité, opèrent à leur profit une étonnante appropriation synthétique de ces paradigmes reproductifs. (shrink)

Artificial insemination was the first conceptive technology to be widely used in agriculture. Whereas at the beginning of the twentieth century all cows in England and Wales were mated to bulls, by the end of the 1950s 60% conceived through artificial insemination. By then a national network of ‘cattle breeding centres’ brought AI within the reach of every farmer. In this paper I explore how artificial insemination, which had few supporters in the 1920s and 1930s, was transformed into an ‘indispensable’ (...) method for reproducing cattle. I discuss the factors that made organised AI possible , including changes in cultures of cattle breeding, novel State involvement in bovine reproduction, the rise of new ‘animal breeding research’ centres at Cambridge, Edinburgh and Reading universities, war preparations and central planning by the Milk Marketing Board . I go on to show that the unprecedented focus on bovine reproduction set in motion by the AI centres effectively generated new networks of reproductive research, through these the ‘biopower’ of the farm was incorporated into the clinic. The example of AI shows that by combining the history of reproductive technology in agriculture and medicine we can give a richer account of modern reproduction. (shrink)

Reproduction is central to biology and evolution. Standard concepts of reproduction are drawn from animals. Nonstandard examples of reproduction can be found in unicellular eukaryotes that distribute their reproductive strategies across multiple generations, and in mutualistic systems that combine different modes of reproduction across multiple lineages. Examining multigenerational and multilineal reproducers and how they align fitness has implications for conceptualizing units of evolution.

While niche construction theory and developmental approaches to evolution have brought to the front the active role of organisms as ecological and developmental agents, respectively, the role of agents in reproduction has been widely neglected by organismal perspectives of evolution. This paper addresses this problem by proposing an agential view of reproduction and shows that such a perspective has implications for the explanation of the origin of modes of reproduction, the evolvability of reproductive modes, and the coevolution (...) between reproduction and social behavior. After introducing the two prevalent views of agency in evolutionary biology, namely those of organismal agency and selective agency, I contrast these two perspectives as applied to the evolution of animal reproduction. Taking eutherian pregnancy as a case study, I wonder whether organismal approaches to agency forged in the frame of niche construction and developmental plasticity theories can account for the goal-directed activities involved in reproductive processes. I conclude that the agential role of organisms in reproduction is irreducible to developmental and ecological agency, and that reproductive goals need to be included into our definitions of organismal agency. I then explore the evolutionary consequences of endorsing an agential approach to reproduction, showing how such an approach might illuminate our understanding of the evolutionary origination and developmental evolvability of reproductive modes. Finally, I analyze recent studies on the coevolution between viviparity and social behavior in vertebrates to suggest that an agential notion of reproduction can provide unforeseen links between developmental and ecological agency. (shrink)

This paper looks at the role nonhuman animals play in how we think about sex, gender, and sexuality in zoology and in society. In examining the history of ideas regarding a microscopic invertebrate species—rotifers—the paper explores how humans have projected aspects of their lives onto nonhuman animals and how they have extrapolated from nonhuman animals to human society. The paper emphasizes the intersections between knowledge about nonhuman animals and gender and sexuality politics.

This book further develops the interventionist literature on wild animal suffering using different theoretical frameworks, including some that have never previously been used to ground our positive duties to wild animals.------------Though we’ve always known that the wild is a nasty place where predators lethally attack prey, only recently have most animal ethicists come to realize that most wild animals fail to flourish. In fact, what we know about wild animal reproduction suggests that the majority of sentient (...) beings born into the world may not even live lives worth living. It’s not unreasonable for one to initially respond to the above with a sense of depressed resignation, but a growing number of ethicists believe that we both can and should intervene. The purpose of this book is to further develop the interventionist literature by bringing together philosophers who agree that we have significant duties to help wild animals, but who use different theoretical frameworks, or who disagree about the details, e.g., about the reasons that ground our obligations to help wild animals, about how those obligations should be classified, about the content of our obligations, about the means we should use to fulfill our obligations, etc.------------This book will be an invaluable resource for scholars, researchers and students of animal ethics, animal welfare, environmental ethics, philosophy, and sustainability. It was originally published as a special issue of the journal Ethics, Policy & Environment. (shrink)

The continuing existence of zoos and their good purposes such as conservation, science, education, and recreation, can be ethically justified only if zoos guarantee the welfare of their animals. The usual criteria for measuring animal welfare in zoos are physical health, long life, and reproduction. This paper looks at these criteria and finds them insufficient. Additional criteria are submitted to expand the range of welfare considerations: natural and abnormal behavior; freedom and choice; and dignity. All these criteria should (...) play a role in analyzing zoo animal welfare and interests but dignity has the overriding part because it impacts on both animal and human interests. (shrink)

In this essay, I argue that those who embrace animal rights should also embrace primitivism—the view that humans should abandon modern technology and take up something like hunter-gatherer technology instead. I call my view “animal-rights primitivism” to distinguish it from human-centered arguments for primitivism. In particular, I employ a vital-needs framework to make my argument. I argue that hunter-gatherer technology is the least harmful kind of technology, it is sufficient to meet human vital needs, and it is possible (...) for humans to make the transition to hunter-gatherer technology while still meeting their vital needs. Alternatively, I argue that even if humans cannot make the transition while still meeting their vital needs, they are responsible for putting themselves in that situation and therefore forfeit the right to aggress against other sentient species to do so. (shrink)

This essay develops an ecofeminist, environmental justice perspective on the shortcomings of “choice” rhetoric in the politics of women’s reproductive self-determination, specifically around fertility-enhancing technologies. These new reproductive technologies (NRTs) medicalize and thus depoliticize the contemporary phenomenon of decreased fertility in first-world industrialized societies, personalizing and privatizing both the problem and the solution when the root of this phenomenon may be more usefully addressed as a problem of PCBs, POPs, and other toxic by-products of industrialized culture that are degrading our (...) personal and environmental health. The NRTs’ rhetoric of choice is implicitly antifeminist: it blames the victim by attributing rising infertility rates to middle-class women who delay childbearing while struggling to launch careers; it conceals information about adverse health effects and solicits egg donation and gestation services from women disadvantaged by economic status, nation, and age; and it offers no choice at all for the millions of female animals—chicks, cows, turkeys, pigs, and others—whose fertility is regularly manipulated and whose offspring are commodified as products for industrialized animal food production. An intersectional analysis shifts the discourse away from reproductive choice to a framework of ecological, feminist, and reproductive justice. (shrink)

This paper traces the history of the Animal Research Station, Cambridge from its establishment in 1932 to its closure in 1986. The author worked there for forty years and was Director from 1979. Originally set up as a field station for Cambridge University’s School of Agriculture, the Station was expanded after World War II as the Agricultural Research Council’s Unit of Animal Reproduction. Beginning with semen and artificial insemination, research at the Station soon embraced superovulation and embryo (...) transfer in farm animals. Many other technologies were also developed here, including IVF in pigs, cloning by nuclear transplantation of early embryonic cells, and the first genetically modified farm animals in Britain. This account recalls the Directors of the Station and their research teams together with details of their pioneering contribution to reproductive biology. (shrink)

Replacing animal procedures with methods such as cells and tissues in vitro, volunteer studies, physicochemical techniques and computer modelling, is driven by legislative, scientific and moral imperatives. Non‐animal approaches are now considered as advanced methods that can overcome many of the limitations of animal experiments. In testing medicines and chemicals, in vitro assays have spared hundreds of thousands of animals. In contrast, academic animal use continues to rise and the concept of replacement seems less well accepted (...) in university research. Even so, some animal procedures have been replaced in neurological, reproductive and dentistry research and progress is being made in fields such as respiratory illnesses, pain and sepsis. Systematic reviews of the transferability of animal data to the clinical setting may encourage a fresh look for novel non‐animal methods and, as mainstream funding becomes available, more advances in replacement are expected. BioEssays 29:918–926, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

This paper discusses Aristotle’s theory of reproduction: specifically, the good that he thinks organisms attain by reproducing. The aim of this paper is to refute the widespread theory that Aristotle believes plants and animals reproduce for the sake of attenuated immortality. This interpretive claim plays an important role in supporting one leading interpretation of Aristotle’s teleology: the theory that Aristotelian nature is teleologically oriented with a view solely to what benefits individual organisms, and what benefits the organism is its (...) survival and well–being. This paper challenges the theories that Aristotle takes plants and animals to reproduce for the sake of attenuated immortality, and that he believes survival to be the most basic of goods. It is argued that Aristotle believes reproduction is detrimental to organisms’ health and longevity but nonetheless is central to plant and animal flourishing. It is claimed that, to explain the fundamentality of the reproductive soul function, Aristotle appeals to the eternal and divine. (shrink)

Which and how much of our current drives –individually and as a global community– are driven by ancestral, inherited traits or imprinted on our animal condition? An attempt to approximate this intriguing query is explored here. It pertains to our identity, social constructions, and our ecological interaction. The origin of our species has its roots in ancestral habits, behaviors and a survival drive, transformed from changing environmental conditions. We were not born in a mother-of-pearl cradle nor were protected by (...) magical agents. We grew on the thread of time within the complex nature of bio-ecological interactions. They carved our identity, our genetic expression and the possible origin of our beliefs, resulting in an arch of various behaviors and cultural phenotypes. The biological nature of our construction dragged through millennia through species trials with variable rates of survival times provided traces of inconstant and multiple evolutive chains. Our modern cultural contexts –norms, priorities, values– appear as newly born. Yet, socio-cultural ecology upon which our brain organization and behavioral constructs derive include shared basic behavioral drives with non-human primates. The emergence of humans with a sophisticated language allowed the development of complex virtual constructs based on symbolism and the instruments of culture. This has enhanced cognitive capacity and emotional interaction supported by processes anchored in neural networks distributed within cortical and subcortical levels. Basic, essential neural connectivities were preserved during the evolutionary development of the species. The biological matrix and inheritance are usually segregated from the social and cultural construction. Sophistication of our cultural development tends to set up a divisive fault from primitive foundations of non-human animal behavior (survival, territory, reproduction, prevalence, access to nutrients). These are basic templates and underlie essential individual and group basic drives, and cultural constructs. Humans have not ceased from being territorial (whether applied to virtual or material dimensions). Various forms of social inequities have been expressed in our time and through human history. On evolutive terms, the notion of individual social status within the social structure of a gregarious community generated the probability of an individual ascending or descending that hierarchy. Thus, becoming a potential figure of leadership, or the subordinate or the marginalized. Is there an evolutive antecedent for human social inequities? How do we construct a different future? Post-industrial societies became increasingly dependent on material consumerism and technological cultures, to the point of embraining them; conceptually becoming technological hybrids. Are these a developmental must, or an uncontrolled spin-off of human inventiveness affecting our future? Construction of supernatural agents played a significant role in the socialization/domestication processes. Agents’ intentionality flourished through altered states of conscience, or under fear of natural phenomena attributed to supposed inhabitants of the Natural Kingdom or virtual beings. This imaginary universe, reinforced by ritual behaviors, contributed to control personal/collective distress of various possible origins and conditioned our degrees of emotional and cognitive freedom. (shrink)

ABSTRACT‘Solidarity’ is a key concept in political movements and usually bears on matters of labour, health and social justice. As such, it is essential in the reproduction and transformation of communities that support their members and protect their interests. It is sometimes overlooked that interspecies solidarity already pertains with a number of domesticated animals, and that people are willing to carry substantial emotional, financial and social burdens to benefit them. There has been even more reluctance to acknowledge wild animals (...) as fellow members of our political communities with whom we might stand in solidarity. The purpose of this paper is to propose that solidaristic relations with certain wild animals are not only possible, but also already exist in some contexts. It explores three different understandings of solidarity, and in probing to what extent they can be applied to wild animals, it identifies some important different roles they can play in ‘animal politics’, and shows how they can help us reconceive our communities in less anthropocentric terms. (shrink)

Artificial gametes, derived from stem cells, have the potential to enable in vitro fertilization of embryos. Currently, artificial gametes are only being generated in laboratory animals; however, considerable efforts are underway to develop artificial gametes using human cell sources. These artificial gametes are being proposed as a means to address infertility through assisted reproductive technologies. Nonetheless, the availability of artificial gametes obtained from adult organisms can potentially expand the possibilities of reproduction. Various groups, such as same-sex couples, post-menopausal women, (...) and deceased donors, could potentially utilize artificial gametes to conceive genetically related offspring. The advent of artificial gametes raises significant bioethical questions. Should all these reproductive scenarios be accepted? How can we delineate the range of future reproductive choices? A normative bioethical framework may be necessary to establish a consensus regarding the use of human artificial gametes. This review aims to present the current state of research on the biological roadmap for generating artificial gametes, while also summarizing proposed approaches to establish a normative framework that delineates ethically acceptable paths for reproduction. (shrink)

In this paper we argue that there is much to learn about “wild justice” and the evolutionary origins of morality – behaving fairly – by studying social play behavior in group-living mammals. Because of its relatively wide distribution among the mammals, ethological investigation of play, informed by interdisciplinary cooperation, can provide a comparative perspective on the evolution of ethical behavior that is broader than is provided by the usual focus on primate sociality. Careful analysis of social play reveals rules of (...) engagement that guide animals in their social encounters. Because of its significance in development, play may provide a foundation of fairness for other forms of cooperation that are advantageous to group living. Questions about the evolutionary roots of cooperation, fairness, trust, forgiveness, and morality are best answered by attention to the details of what animals do when they engage in social play – how they negotiate agreements to cooperate, to forgive, to behave fairly, and to develop trust. We consider questions such as why play fairly? Why did play evolve as it has? Does “being fair” mean being more fit? Do individual variations in play influence an individual’s reproductive fitness? Can we use information about the foundations of moral behavior in animals to help us understand ourselves? We conclude that there is likely to be strong selection for cooperative fair play because there are mutual benefits when individuals adopt this strategy and group stability may also be fostered. Numerous mechanisms have evolved to facilitate the initiation and maintenance of social play, to keep others engaged, so that agreeing to play fairly and the resulting benefits of doing so can be readily achieved. (shrink)

The fundamental postulate of sociobiology is that individuals exploit favorable environments to increase their genetic representation in the next generation. The data on fertility differentials among contemporary humans are not cotvietent with this postulate. Given the importance ofHomo sapiensas an animal species in the natural world today, these data constitute particularly challenging and interesting problem for both human sociobiology and sociobiology as a whole.The first part of this paper reviews the evidence showing an inverse relationship between reproductive fitness and (...) “endowment” (i.e. wealth, success, and measured aptitudes) in contemporary, urbanized societies. It is shown that a positive relationship is observed only for those cohorts who bore their children during a unique period of rising fertility, 1935–1960, and that these cohorts are most often cited by sociobiologists as supporting the central postulate of sociobiology. Cohorts preceding and following these show the characteristic inverse relationship between endowment and fertility. The second section reviews the existing so-ciobiological models of this inverse relationship, namely, those of Barkow, Burley, and Irons, as well as more informal responses among sociobiologists to the persistent violation of sociobiology's central postulate, such as those of Alexander and Dawkins. The third section asks whether the goals of sociobiology, given the violation of its fundamental postulate by contemporary human societies, might not be better thought of as applied rather than descriptive, with respect to these societies. A proper answer to this question begins with the measurement of the pace and direction of natural selection within modern human populations, as compared to other sources of change. The vast preponderance of the shifts in human trait distributions, including the IQ distribution, appears to be due to environmental rather than genetic change. However, there remains the question of just how elastic these distributions are in the absence of reinforcing genetic change. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Human Reproduction: Dominion and LimitsRichard A. McCormick S.J. (bio)The general struggle throughout Christian history has been to seek the proper balance between dominion and limits, intervention and nonintervention, givenness, and creativity. This struggle has worked itself out in six areas that touch human life. In this essay, I will revisit the Catholic tradition’s treatment of these in terms of dominion and limits to see whether we can discern (...) developmental patterns that might suggest an approach to issues pertaining to the sources of life (reproductive ethics) as we move into the next century.1. Abortion. The history of the treatment of abortion in the Catholic tradition is the history of an evaluation. This evaluation was somewhat muddied by [End Page 387] unclarity and inconsistency in the use of terms. Thus, some theologians distinguished three types of abortion: prevention of conception, abortion of an inanimate fetus, and abortion of an animated fetus. Others regarded all interventions into the life-giving process as homicides. Still others argued that termination of a nonanimated fetus was justified to save the life of the mother. And still others said such termination was anticipated homicide or the misuse of semen conceptum.Such unclarities and qualifications eventually vanished and produced an evaluation of fetal life that yielded to very few competing interests, what John Noonan (1970) referred to as “an almost absolute value.” There was some dominion or control, but the limits became increasingly clear and powerful.2. Individual and corporate self-defense. Augustine disallowed lethal individual or personal self-defense, but established the first elementary rules for war. Aquinas allowed both. Vitoria, Suarez, and others refined the criteria justifying war (jus ad bellum) and listed them as three: recovery of property, resistance to aggression, and vindication of injuries (injustices). Pius XII narrowed these to a single reason: national self-defense. The Challenge of Peace (NCCB 1983) moves away from the licitness of nuclear war and nuclear deterrence even for self-defense. Once again, the limits to the dominion over life in war grow stronger and more powerful even as the weapons of such dominion grow more powerful.3. Capital punishment. Over the centuries, Christian thinkers, such as Thomas Aquinas, permitted the use of capital punishment. Three justifications were proposed to found this right of the state: retribution, deterrence, and reform. In the past decades, however, these justifications have been seriously questioned. Both the American and Philippine bishops’ conferences have rejected all use of capital punishment. Most recently John Paul II (1995, n. 56, p. 709) adduces defense of society as the only possible justification for it and sees such cases as “very rare if not practically non-existent.”4. The preservation of life. The theme of a balance between dominion and limits is perhaps nowhere clearer than in the Catholic approach to life preservation. Catholic tradition does not accept our culture’s rejection of death. Rather it asserts that the facts that we are pilgrims, that Christ has overcome death and lives, and that we also will live with him yield a general value judgment on the meaning and value of life as we now live it: Life is a basic good but not an absolute one. It is basic because, as the Congregation for the Doctrine of the Faith (1980, p. 511) worded it, it is the “necessary source and condition of every human activity and of all society.” It is not absolute because there are higher goods for which life can be sacrificed—e.g., the glory of God, salvation of souls, service of one’s brethren, and the like. Thus in John (15:13): “There is no greater love than this: to lay down one’s life for one’s friends. John Paul II (1995, n. 47, p. 706) briefly summarizes this in Evangelium Vitae: “The life of the body in its earthly state is not an absolute good for the believer.” This value [End Page 388] judgment has immediate relevance for care of the ill and dying: Not all means must be used to preserve life.Thus the Catholic tradition has moved between two extremes: medico-moral optimism or vitalism (which preserves life with all means, at any cost... (shrink)

Influential parts of the veterinary profession, and notably the American Veterinary Medicine Association, are promoting the routine neutering of cats and dogs that will not be used for breeding purposes. However, this view is not universally held, even among representatives of the veterinary profession. In particular, some veterinary associations in Europe defend the view that when reproduction is not an issue, then neutering, particularly of dogs, should be decided on a case-by-case basis. However, even in Europe the American view (...) is gaining ground. In light of this situation, this paper considers whether or not routine neutering of cats and dogs, in cases where uncontrolled reproduction is not an issue, can be ethically defended. The starting point of this consideration is a review of the veterinary literature on the effects of neutering on companion animals. The focus is both on the welfare of neutered animals themselves, and on behavioral and other effects that may not directly affect the animals’ welfare, but that maybe motivating factors for owners to neuter their companion animals. Here it becomes clear that justification for routine neutering, particularly of confined male dogs, does not follow from claims about the dogs’ own welfare. The costs of neutering male dogs, in terms of the increased risk of very serious diseases, may well outweigh the benefits. Then, building on this veterinary material, but including some other, additional considerations, the paper goes through some possible ethical approaches to routine animal neutering. These ethical approaches offer different degrees of concern about, or opposition to, routine neutering. Finally, based on this ethical exploration, it is argued that routine neutering, at least in the case of non- free-ranging companion animals, raises significant ethical questions, and from some ethical perspectives, looks highly problematic. (shrink)

Abstract.Since the gene splicing debates of the 1980s, the public has been exposed to an ongoing sequence of genetic and reproductive technologies. Many issue areas have outcomes that lose track of people's inner values or engender opposing religious viewpoints defying final resolution. This essay relocates the discussion of what is an acceptable application from the individual to the societal level, examining technologies that stand to address large numbers of people and thus call for policy resolution, rather than individual fiat, in (...) their application. A major source of guidance is the “Genetic Frontiers” series of professional dialogues and conferences held by the National Conference for Community and Justice from 2002 to 2004. Genetic testing, human gene therapy, genetic engineering of plants and animals, and stem cell technology are examined. While differences in perspective on the beginning of life persist, a stepwise approach to the examination of genetic testing reveals areas of general agreement. Stewardship of life, human co‐creativity with the divine, and social justice help define the bounds of application of genetic engineering and therapy; compassionate care plays a major role in establishing stem cell policy. Active, sustained dialogue is a useful resource for enabling sharing of religious values and crystallization of policies. (shrink)

Aristotle refers to some animal kinds as μέγιστα γένη, or greatest kinds. The goal of this paper is to make clear the nature and significance of these kinds. I argue that Aristotle thinks of greatest kinds as the most general kinds within a specified domain. I then consider the fact that Aristotle’s discussion of animals’ reproductive parts and modes of reproduction in Generation of Animals is organized around divisions related to the cause of each of the features being (...) explained. I conclude that, while classification is an important goal in Aristotle’s biological treatises, it is of little significance that some of the kinds he identifies are referred to as greatest kinds. The important divisions are, for Aristotle, the divisions that best serve his goal of explaining the various features of animals and these divisions sometimes group together and sometimes cut across the commonly recognized, including the greatest, animal kinds. (shrink)

Darwin's theory of evolution brought to an end the static view of nature. It was no longer possible to think of species as immortal, with secure places in nature. Fluctuation of population could no longer be thought of as occurring within definite limits which had been set at the time of creation. Nor was it any longer possible to generalize from the differential reproductive potentials, or from a few cases of mutualism between species, that everything in nature was “fitted to (...) produce general ends, and reciprocal uses.” 134 The appeal to “design” could no longer be substituted for answers to questions concerning animal demography. Instead, the dynamics of a population had to be viewed as the outcome of species' struggle against animate and inanimate factors in the environment. Both the members of a species and the environmental factors tend to vary randomly, and therefore neither evolution nor population dynamics could be fully understood alone. For this reason Darwin's linking of the two subjects was inevitable and not merely an historical accident. Since Darwin had shown that no automatic equilibrium existed, he demonstrated the importance of closer study of the causes of population dynamics and extinction. He also indicated that an understanding of population depends upon the development of a broad knowledge in ecology.Viewed from another direction, Darwin's work ended the early modern era of population studies by clarifying three interrelated problems which were important for understanding population: extinction, distribution, and the nature of species. The components of his answer had been discussed in the eighteenth century, but there had not existed enough evidence for the completion of the revolution in thought which had then begun. At the beginning of the nineteenth century, Playfair found the evidence for extinction conclusive, and, in spite of Lamarck, Curvier convinced the scientific world that there could no longer be any doubt about it. This was a step the importance of which, with his limited knowledge of biogeography and population, Cuvier could not have fully realized. Lamarck attempted, with his evolutionary theory, to circumvent the necessity for admitting extinction, but he overestimated the adaptability of organisms and in doing so he underestimated the importance of competition and the whole field of ecology. On the other hand, he was not willing to let questions such as the origin of species remain taboo to science. The origin of species was a biogeographical as well as a paleontological question. Humboldt correlated environment with the distribution of species and conveyed the impression that plant communities are subject to change. De Candolle, following the lead of Linnaeus and Humboldt, emphasized the ecological aspects of biogeography, not only the importance of habitat and range, clearly showing the ecological effects of competition. The entomologists Kirby and Spence took a faltering step toward understanding the relationship between population and ecological role, but they fell short of any significant new conclusions. Neither they nor Swainson could fully comprehend the new perspective of De Candolle.Lyell was able to bring together the evidence from these three lines of investigation and weave them into an important synthesis that almost accomplished that Darwin later did. Although opposing Lamarck's theory of evolution, Lyell had a dynamic view of ecology. He realized that population dynamics offered an important key to the understanding of biogeography. Since he knew that species become extinct, he investigated closely the factors which could either preserve or extinguish species. While explaining these factors, he described the interrelationships of species in greater detail than had ever been done before. Forbes continued to develop Lyell's ecological concepts, and his first-hand field experience enabled him to describe biotic communities more concretely than Lyell had.Having the advantages of Lyell's understanding and his own experience from a global voyage, Darwin could take the final step from the static to the dynamic concept of life. He had seen populations fluctuating and also fossil species in South America, and on the Galapagos Islands he had encountered a biogeographical problem that could not be credibly solved without the idea of evolution. However, the bare idea of evolution did not fully answer his questions. He sought physiological causes of extinction before he read Malthus and realized that De Candolle and Lyell had correctly emphasized the importance of competition. Darwin found that, in order to understand evolution, he needed to improve his understanding of ecology. He wanted to know when populations were most easily decimated, how extensive were competition and cooperation, what effects parasites have upon populations, and what changes occur in biotic communities when a species is either added or subtracted. He contributed to some extent to answering these questions. Though there remained much for others to do, there was now a new and more secure theoretical framework within which later studies could be interpreted. As Ernst Mayr has observed, Darwin's “consistent thinking in terms of population has had an impact on biological theory and practice which is second only to his sponsorship of natural selection as the mechanism of evolution.” 135. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Animals in the World: Five Essays on Aristotle’s Biology by Pierre PellegrinChristopher LutzPELLEGRIN, Pierre. Animals in the World: Five Essays on Aristotle’s Biology. Translated by Anthony Preus. Albany: State University of New York Press, 2023. vi + 324 pp. Cloth, $95.00; paper, $35.95This book explores two broad questions that have for decades been driving Pierre Pellegrin’s contributions to the so-called biological turn in Aristotle studies: whether and in (...) what sense Aristotle actually has a biology; the degree to which Aristotle’s teleological commitments lead him to characterize living things and the world that they inhabit as perfect. By analyzing various interplays that the zoological treatises posit between, on the one hand, the form and end of each species and, on the other hand, its material and efficient causes, Pellegrin reveals the astounding depth of Aristotle’s affinity with modern biology.In consideration of the millennia-spanning distance between Aristotle and the emergence of modern biology in the nineteenth century, Pellegrin first of all seeks to establish that he may call Aristotle a biologist without committing anachronism. Chapter 1 identifies two teleological notions that connect Parts of Animals and Generation of Animals to nineteenth-century conceptions of biology: Using organic function as the primary organizational principle in comparative anatomy relates Aristotle to Cuvier, and the concept of adaptation relates Aristotle to Darwin. Citing the profound influence of History of Animals on Cuvier (and thus on nineteenth-century biology), Pellegrin argues that its chief biological [End Page 357] innovation lies in the suggestion that observation is epistemically useful even when we are unable to explain that which we have observed.Chapter 2 emphasizes the role that mechanistic (that is, material and efficient) causality plays within the teleological explanations in Aristotle’s studies of animals. After a lengthy discussion of hypothetical necessity, Pellegrin uses PA 1.1’s distinction between formal nature and material nature to suggest that Aristotle recognizes an “ontological autonomy” of material nature, by which he seems to mean that matter has certain properties independent of any form. Linking Aristotle to Darwin, he argues that for Aristotle the perfection of each species consists in its fitness for (everlasting) survival. The end-directed formal nature of the species must negotiate with its autonomous material nature in order to secure for it an advantageous condition that guarantees its permanence but inevitably comes at the expense of certain disadvantages. For example, birds have no ears because they need extra matter for feathers (see PA 2.12).Shifting the focus to a crucial difference between Aristotle and modern biology, chapter 3 investigates the unity of Aristotelian natural science and biology’s place within it. Pellegrin finds analogies between Aristotle’s explanations of sexual reproduction, spontaneous generation, and Meteorology ’s account of the formation of inanimate homoiomerous matter (for example, metals, minerals). Sexual reproduction (clearly involving a material, formal, efficient, and final cause) is more causally complex than spontaneous generation (which according to Pellegrin has no preexisting final cause and only a quasi-formal cause), yet we understand spontaneous generation only by analogy with sexual reproduction, which is for Aristotle explanatorily prior. Spontaneous generation, in turn, is marginally more complex than the formation of homoiomerous matter (which also has only a quasi-formal cause and, further, no final cause at all), yet we understand the latter only by analogy with spontaneous generation and sexual reproduction. Pellegrin concludes that all natural science is united insofar as “material-efficient causality concerns all natural realities,” living and nonliving alike; however, because Aristotle in each case explains the less complex by analogy with the more complex, the teleological study of fully developed living things is explanatorily primary within his natural science. In this way, Aristotle stands in stark contrast to modern natural science, in which biology is explanatorily posterior to chemistry and physics.Chapter 4 qualifies the explanatory priority of complex organisms by challenging any notion of an Aristotelian scala naturae. Pellegrin works to show that the recognition of irreducible diversity is present in Aristotle’s very definition of an animal, arguing that in animals the nutritive faculty is neither ontologically nor developmentally prior to the sensitive and motive... (shrink)

This chapter contains sections titled: The Place of GA in Aristotle's Philosophy Male and Female as archai The Nature of Sperma The Transmission of Soul: GA II.3 Reproductive Hylomorphism Inheritance Individual Forms Four Causes of Generation Notes Bibliography.

A common view of politics is that it is reducible to applied ethics. If politics, in a classic phrase, is about “who gets what, when, and how,” then the task of normative political theory would simply be to tell us who is morally entitled to get whatever the “what” is in that statement.This view, however, can easily reduce politics to a dizzying vortex of actions to assess from an ethical perspective. And while the task of moral philosophy may be precisely (...) to articulate principles by which to pass such judgment, the focus of political theory lies elsewhere.To study and assess politics means attending to the institutional frameworks and structural conditions that enable or constrain human action to begin with. The question for normative political theory, in other words, is whether the organizational structure of a given society—embodied in its decision-making procedures, its distribution of power, and its defining patterns of production, reproduction, and distribution—is defensible or not.This question of justice in the institutional makeup of society has not been entirely ignored in animal rights literature. Animal advocates have always been clear about the massive societal ramifications of dismantling the speciesist order. Likewise, rights theorists and activists have often proposed concrete legal measures for improving the protection of animals, be it by piecemeal welfare reform in animal agriculture, by the abolition of specific practices in biomedical research, or by seeking the equivalent of human rights for select species like great apes or dolphins. The field has also seen fierce debate among animal advocates about the appropriate strategies for engaging with the state and the legal system.Nonetheless, most discussions have been about what it means to treat individual animals with respect, and not about what is required of a political order aspiring to just treatment of all species. In fact, it is only in the last decade that the issue of political justice has taken up a place at the center of animal ethics.Though the field is still developing, we may take it as a sign of maturity that it can now sport its first “short introduction” book: Alasdair Cochrane's Should Animals Have Political Rights? (2020). Its appearing as part of the Polity Press series Political Theory Today further attests to the book's timeliness.The starting point of Cochrane's book—and of political animal studies in general—is that political relations between humans and other animals are not optional but inevitable. Other animals live among us, and the way we organize our societies has a massive impact on the lives of other sentient animals both inside and outside the borders of our human communities. Assuming that these creatures possess intrinsic value as experiencing individuals with morally relevant interests, the question seems inescapable: What kind of polity can accommodate for the multispecies character of our communities and embody justice for all sentients? Cochrane's answer is largely the same as the one he offered in his previous book, Sentientist Politics: A Theory of Global Inter-Species Justice (Oxford University Press, 2018), where he laid out his full vision of a postnational and species-neutral “cosmozoopolis.”The present book is much more concentrated and written as an accessible introduction for readers new to the field. Over seven short chapters, Cochrane reconstructs his argument for an interspecies democracy by assessing a series of arguments and propositions drawn from previous literature on the topic.The first notion to be scrutinized is the popular idea that animal welfare legislation is enough to secure respect for animals. Here, Cochrane acknowledges that welfarism goes some way toward safeguarding animal interests, but he also stresses that its historical record has been disheartening. Welfarism protects animals only insofar as their protection coincides with human interests, and this is far from enough to ensure respect for the animals’ intrinsic value.The second line of argument tries to push beyond welfarism by claiming constitutional protection for animals. By this move, reformers hope to place animal interests on an equal footing with human interests and prevent the overriding of the former in the name of human entitlements (to property, artistic expression, freedom of science, and so forth). Looking at real-world cases, however, Cochrane finds that these constitutional provisions tend to be sidelined when they come into conflict with the interests of big agribusiness.Noting that more than constitutional protection is needed, Cochrane turns to a third set of arguments about legal personhood for animals. Winning personhood for animals would certainly constitute a radical step toward equalizing the interests of different species. Nonetheless, Cochrane argues that personhood alone would be insufficient. Intrinsic value, to him, cannot be fully respected unless animals win the political right to have their interests factor into society's articulation of the public good. As sentient beings, we can all make a claim on the political communities we are part of to not only recognize us as members but furnish us with the means to live well.The fourth and final step for Cochrane is to argue that democratic representation for animals is necessary for realizing these political membership rights. Without representation, he contends, political rights risk being watered down, leaving animals with much less than they are entitled to as sentient beings. Cochrane critically discusses several different models for how this representation could be organized. While he is partial to a system where specially trained human representatives are tasked with voicing the animals’ interests in the legislative process, he leaves many of the practicalities open for future experimentation.Readers familiar with the field of political animal studies will find little new in Should Animals Have Political Rights? For students new to the field, however, Cochrane's book does an excellent job introducing the main issues in a very accessible format. Students of “regular” political science will also benefit from the book's fresh challenge to the discipline's understanding of “the political” as well as its important insights into the relationship between individual and political rights. (shrink)

Aristotle's account of female nature has received mostly negative treatment, emphasising what he says females cannot do. Building on recent research, this book comprehensively revises such readings, setting out the complex and positive role played by the female in Aristotle's thought with a particular focus on the longest surviving treatise on reproduction in the ancient corpus, the Generation of Animals. It provides new interpretations of the nature of Aristotle's sexism, his theory of male and female interaction in generation, and (...) his account of inherited features. It also discusses a range of more general issues which can and should be re-examined in light of Aristotle's account of female animals: his methodology, hylomorphism, teleology and psychology. Aristotle on Female Animals will be valuable to all those interested in Aristotle's philosophy and the history of gender. (shrink)

ABSTRACT Recent developments in generating gametes via in vitro gametogenesis (IVG) from induced pluripotent stem cells (iPSCs) and their successful use for reproductive purposes in animals strongly suggest that soon these methods could also be used in human reproduction. At least two questions emerge in this context: (a) if a legislator should permit their use and (b) if ethical claims emerge that support their provision, e.g., by public health care systems. This urges an ethical reflection of the new reproductive (...) options this technique might offer. Since the concept of reproductive freedom is a key aspect for the ethical evaluation of artificial reproductive technologies (ARTs), it is necessary to analyze if the new possibilities emerging from IVG fall within the scope of this concept. The results may constitute a morally relevant difference between different imaginable applications of IVG and potentially justify differences in claims to access this technology. (shrink)

This chapter is an examination of the way aporiai are employed in Aristotle’s scientific account of animal reproduction, and how they are resolved. I argue that – surprising as it may be, given what Aristotle says in Metaphysics B about the importance of going through aporiai – there seems to be nothing of much significance about his use of them, at least if we assume that genuine cases of aporiai are being tracked by use of aporia-language. I demonstrate (...) this negative thesis by systematically going through the examples. There seems to be no common purpose for which they are raised, they have no single type of structure, and they are not caused by any one sort of difficulty. (shrink)

The discussion of the soul as a principle of life in ancient Greek philosophy was not limited to the soul’s relation to the body, the capacities of the soul, and the functions of the living organism. The debates about the soul and life also concerned issues of embryogenesis, such as the generation, formation, and animation of an organic body in the womb. The fragments of these debates can be traced in the writings of Alexander of Aphrodisias, particularly in his treatise (...) On the Soul. In this paper, I examine Alexander’s views on animal reproduction, especially considering the problematic question of the life and animation of the embryo. Analyzing generation among the other capacities of the nutritive soul in On the Soul, Alexander considers the causes of embryogenesis. As the first cause, he indicates the nutritive capacity, which is transmitted from the parent through the seed and acts in the embryo. In addition, as Simplicius states in his commentary on Aristotle’s Physics, Alexander claims that the soul of the parent acts as a paradeigma that specifies the order and the goal of the embryo’s development. Thus, I explain Alexander’s understanding of the causes of the embryo’s development and animation in the context of his idea of the soul as a capacity (δύναμις) and state (ἕξις). (shrink)

Originally applied on domestic and lab animals, assisted reproduction technologies (ARTs) have also found application in conservation breeding programs, where they can make the genetic management of populations more efficient, and increase the number of individuals per generation. However, their application in wildlife conservation opens up new ethical scenarios that have not yet been fully explored. This study presents a frame for the ethical analysis of the application of ART procedures in conservation based on the Ethical Matrix (EM), and (...) discusses a specific case study—ovum pick-up (OPU) procedures performed in the current conservation efforts for the northern white rhinoceros (Ceratotherium simum cottoni)—providing a template for the assessment of ART procedures in projects involving other endangered species. (shrink)

Unrestricted reproductive rights for domesticated animals, including the right to roam freely, will have serious consequences for domesticated animals in today's world. While political and legal theories focus on population control to justify fertility restrictions, they do so to save animals’ lives, and one consequence of restricting domesticated animals’ reproductive rights is many more animal deaths. Further, theorists have explored whether population control methods unjustifiably infringe on animals’ rights and argue that at least some are not only justified but (...) arguably mandated under animal rights theories. And finally, it is doubtful today that unbridled reproductive rights for domesticated animals that protect their rights to freedom of association and mobility is in their best interests. (shrink)

Best known as a moralist and one of the founders of the Scottish Common Sense school of philosophy, Thomas Reid was also an influential scientific thinker. Here his work on the life sciences is studied in detail, bringing together unpublished transcripts of his most important papers on natural history, physiology, and materialist metaphysics. Part I provides the first published account of Reid's reflections on the highly controversial theories surrounding muscular motion and the reproduction of plants and animals and relates (...) them to the broader Enlightenment debates on these issues. It also contains the first systematic reconstruction of Reid's opposition to materialism and views his polemics against the noted Dissenter Joseph Priestley in terms of their differing interpretations of the Newtonian legacy, their conflicting philosophical assumptions, and the cultural politics of Common Sense philosophy in the 1770s. Part II reproduces a selection of Reid's most significant papers on the life sciences, including his Glasgow Literary Society discourses on muscular motion and on Priestley's materialism, as well as other manuscripts that document the development of his scientific ideas. (shrink)

In 2017, a Philadelphia research team revealed the closest thing to an artificial womb the world had ever seen. The ‘biobag’, if as successful as early animal testing suggests, will change the face of neonatal intensive care. At present, premature neonates born earlier than 22 weeks have no hope of survival. For some time, there have been no significant improvements in mortality rates or incidences of long-term complications for preterms at the viability threshold. Artificial womb technology, that might change (...) these odds, is eagerly anticipated for clinical application. We need to understand whether AWT is an extension of current intensive care or something entirely new. This question is central to determining when and how the biobag should be used on human subjects. This paper examines the science behind AWT and advances two principal claims. First, AWT is conceptually different from conventional intensive care. Identifying why AWT should be understood as distinct demonstrates how it raises different ethico-legal questions. Second, these questions should be formulated without the ‘human being growing in the AW’ being described with inherently value laden terminology. The ‘human being in an AW’ is neither a fetus nor a baby, and the ethical tethers associated with these terms could perpetuate misunderstanding and confusion. Thus, the term ‘gestateling’ should be adopted to refer to this new product of human reproduction: a developing human being gestating ex utero. While this paper does not attempt to solve all the ethical problems associated with AWT, it makes important clarifications that will enable better formulation of relevant ethical questions for future exploration. (shrink)

This essay is an exploration in ethical rhetoric, specifically, the ethics of comparing the status of fetuses and animals to enslaved Africans. On the view of those who make such comparisons, the fetus is treated as a slave through abortion, reproductive technologies, and stem cell research, while animals are enslaved through factory farming, experimentation, and as laborers, circus performers, and the like. I explore how the apotheosis of the fetus and the humanization of animals represent the flipside of the subjugation (...) and animalization of black people. At their ethical best, those who compare aborted fetuses and abused animals with enslaved black people have laudable ethical goals. The anti-abortion right and the animal rights left, respectively, wish to abolish abortion and the unethical treatment of animals. They seek, respectively, to reimagine the ethical-political status of the fetus and to criticize the animalization of animals, the practice of constructing them as beasts. While sympathetic to these goals, I worry about the comparative diminution of the historical, literal enslavement of black people. To what extent, I ask, does the comparative ethical rhetoric of fetal slaves and animal slaves affect historical constructions of black people as beastly and disposable? (shrink)

Recent investigations with non‐model species and whole‐genome approaches have challenged several paradigms in animal epigenetics. They revealed that epigenetic variation in populations is not the mere consequence of genetic variation, but is a semi‐independent or independent source of phenotypic variation, depending on mode of reproduction. DNA methylation is not positively correlated with genome size and phylogenetic position as earlier believed, but has evolved differently between and within higher taxa. Epigenetic marks are usually not completely erased in the zygote (...) and germ cells as generalized from mouse, but often persist and can be transgenerationally inherited, making them evolutionarily relevant. Gene body methylation and promoter methylation are similar in vertebrates and invertebrates with well methylated genomes but transposon silencing through methylation is variable. The new data also suggest that animals use epigenetic mechanisms to cope with rapid environmental changes and to adapt to new environments. The main benefiters are asexual populations, invaders, sessile taxa and long‐lived species. (shrink)

Generation of Animals is one of Aristotle's most mature, sophisticated, and carefully crafted scientific writings. His overall goal is to provide a comprehensive and systematic account of how animals reproduce, including a study of their reproductive organs, what we would call fertilization, embryogenesis, and organogenesis. In this book, international experts present thirteen original essays providing a philosophically and historically informed introduction to this important work. They shed light on the unity and structure of the Generation of Animals, the main theses (...) that Aristotle defends in the work, and the method of inquiry he adopts. They also open up new avenues of exploration of this difficult and still largely unexplored work. The volume will be essential for scholars and students of ancient philosophy as well as of the history and philosophy of science. (shrink)