Pathological tremor is a common but highly complex movement disorder, affecting ~5% of population older than 65 years. Different methodologies have been proposed for its quantification. Nevertheless, the discrimination between Parkinson’s disease tremor and essential tremor remains a daunting clinical challenge, greatly impacting patient treatment and basic research. Here, we propose and compare several movement-based and electromyography-based tremor quantification metrics. For the latter, we identified individual motor unit discharge patterns from high-density surface electromyograms and characterized the neural drive to a (...) single muscle and how it relates to other affected muscles in 27 Parkinson’s disease and 27 essential tremor patients. We also computed several metrics from the literature. The most discriminative metrics were the symmetry of the neural drive to muscles, motor unit synchronization, and the mean log power of the tremor harmonics in movement recordings. Noteworthily, the first two most discriminative metrics were proposed in this study. We then used decision tree modelling to find the most discriminative combinations of individual metrics, which increased the accuracy of tremor type discrimination to 94%. In summary, the proposed neural drive-based metrics were the most accurate at discriminating and characterizing the two most common pathological tremor types. (shrink)

Decidim es una plataforma digital de democracia participativa desarrollada por el Ajuntament de Barcelona. Decidim es, además, un proyecto tecnopolítico que implica multitud de códigos más allá del informático. Distinguimos tres planos analíticos que sirven para conceptualizar de forma holística y sistemática el proyecto Decidim: un plano político, uno tecnopolítico, y un plano técnico. Decidim emerge como ejemplo de lo que denominamos “redes políticas” caracterizadas, frente a las “redes sociales”, por hacer del vínculo político y la construcción de inteligencia y (...) voluntad colectivas el centro de su diseño y estructura. A su vez, la comunidad y los espacios “Metadecidim” operan como dispositivos para la democratización del software de Decidim y de la democracia en red en un sentido más amplio, constituyendo “redes tecnopolíticas”. Estas redes de nueva generación hacen de la plataforma una infraestructura público-común (financiada con dinero público y co-diseñada con la ciudadanía), abierta y libre para la democracia participativa, un proyecto que aspira a servir de dispositivo y modelo para la transformación política en un periodo de crisis de la hegemonía neoliberal. (shrink)

Con frecuencia el avance y uso del conocimiento han sido relacionados como uno de los indicadores más importantes para el desarrollo económico y bienestar social de países y regiones. Sin embargo, independientemente de los factores teórico metodológicos que impulsan el desarrollo del conocimiento, el acceso a este activo intangible se encuentra limitado a diversas condiciones económicas, sociales, culturales e incluso del mismo conocimiento per se que cada individuo desarrolla dentro de la sociedad. El objetivo principal de este trabajo de investigación (...) consiste en realizar un análisis teórico desde una perspectiva sociológica de la ciencia y la tecnología, sobre el papel que desempeña la universidad pública en la democratización del conocimiento al interior de su comunidad y de la sociedad en general, señalando los principales avances y obstáculos que ésta presenta durante la difusión del mismo. (shrink)

In this paper we describe an experimental test of the validity of the Pauli Exclusion Principle (for electrons) which is based on a straightforward idea put forward a few years ago by Ramberg and Snow (Phys. Lett. B 238:438, 1990). We perform a very accurate search of X-rays from the Pauli-forbidden atomic transitions of electrons in the already filled 1S shells of copper atoms. Although the experiment has a very simple structure, it poses deep conceptual and interpretational problems. Here we (...) describe the experimental method and recent experimental results, which we interpret in the framework of quon theory. We also present future plans to upgrade the experimental apparatus using Silicon Drift Detectors. (shrink)

En la actualidad, los desarrollos teóricos acerca de la justicia desde una perspectiva lingüística giran alrededor de la teoría de la justicia de John Rawls y la teoría de la acción comunicativa de Jürgen Habermas. Empero, aunque un estudio detallado del funcionamiento del lenguaje hace parte de estas teorías no pueden concebirse propiamente como filosofías del lenguaje. La filosofía del lenguaje propende por la construcción de una teoría del significado que permita explicar diferentes fenómenos lingüísticos entre los que se encuentran (...) aquellos donde es usado el concepto de justicia. Mientras estas teorías permiten comprender las dinámicas pragmáticas de estos fenómenos, quedan cortas en la comprensión del contenido semántico del concepto. Este contenido semántico es lo que en última instancia aclara la naturaleza del mismo y, por tanto, una teoría del significado que permita dar cuenta tanto de las dinámicas pragmáticas como del contenido semántico será de vital importancia en la aclaración del concepto de justicia. Según este panorama, una salida más viable podría encontrarse en el pensamiento de Robert Brandom y Charles Travis, cuyas teorías del significado están basadas en el pensamiento expuesto en la obra tardía del filósofo Ludwig Wittgenstein. Según este autor, las prácticas de la justicia hacen parte de nuestras formas de vida y si el contenido semántico del concepto de justicia ha de ser buscado en algún lugar, es allí, en esas prácticas, donde será encontrado. La trama de la vida misma es la luz adecuada que puede iluminar la oscuridad en la que se ha sumido el concepto de justicia. Currently, the theoretical developments about justice from a linguistic perspective revolve around the theory of justice of John Rawls and the theory of communicative action of Jürgen Habermas. However, although a detailed study of the functioning of language is part of these theories, they can not be properly conceived as philosophies of language. The philosophy of language tends to the construction of a theory of meaning that allows explaining different linguistic phenomena among which are those where the concept of justice is used. While these theories allow to understand the pragmatic dynamics of these phenomena, they are short in the understanding of the semantic content of the concept. This semantic content is what ultimately clarifies the nature of it and, therefore, a theory of meaning that allows to account both the pragmatic dynamics and the semantic content will be of vital importance in the clarification of the concept of justice. According to this panorama, a more viable exit could be found in the thought of Robert Brandom and Charles Travis, whose theories of meaning are based on the thought expressed in the later work of the philosopher Ludwig Wittgenstein. According to this author, the practices of justice are part of our forms of life and if the semantic content of the concept of justice has to be sought somewhere, it is there, in those practices, where it will be found. The plot of life itself is the adequate light that can illuminate the darkness in which the concept of justice has been submerged. (shrink)

Background: Eye movement desensitization and reprocessing [EMDR] is an innovative, evidence-based and effective psychotherapy for post-traumatic stress disorder [PTSD]. As with other psychotherapies, the effectiveness of EMDR contrasts with a limited knowledge of its underlying mechanism of action. In its relatively short life as a therapeutic option, EMDR has not been without controversy, in particular regarding the role of the bilateral stimulation as an active component of the therapy. The high prevalence of EMDR in clinical practice and the dramatic increase (...) in EMDR research in recent years, with more than 26 randomized controlled trials published to date, highlight the need for a better understanding of its mechanism of action. Methods: We conducted a thorough systematic search of studies published until October 2017, using PubMed, ScienceDirect, Web of Knowledge and Scopus databases that examined the mechanism of action of EMDR or provided conclusions within the framework of current theoretical models of EMDR functioning. Results: Seventy-five studies were selected for review and classified into three overarching models; (i) psychological models (ii) psychophysiological models and (iii) neurobiological models. The evidence available from each study was analysed and discussed. Results demonstrated a reasonable empirical support for the working memory hypothesis and for the physiological changes associated with successful EMDR therapy. Recently, more sophisticated structural and functional neuroimaging studies using high resolution structural and temporal techniques are starting to provide preliminary evidence into the neuronal correlates before, during and after EMDR therapy. Discussion: Despite the increasing number of studies that published in recent years, the research into the mechanisms underlying EDMR therapy are still in its infancy. Studies in well-defined clinical and non-clinical populations, larger sample sizes and tighter methodological control are further needed in order to establish firm conclusions. (shrink)

I argue for a four dimensional, non-dynamical view of space-time, where becoming is not an intrinsic property of reality. This view has many features in common with the Parmenidean conception of the universe. I discuss some recent objections to this position and I offer a comparison of the Parmenidean space-time with an interpretation of Heraclitus’ thought that presents no major antagonism.

Este artículo interpreta tres sueños decisivos que sacudieron a Descartes tomando como punto de partida lo que Heidegger denominó otro inicio de la filosofía en el espanto (das Erschrecken). Por un lado, se mostrará cómo las pesadillas que experimentó Descartes abrían la posibilidad de un pensar inicial. Por otro lado, se detallará cómo Descartes retrocede ante esa posibilidad. Vinculando la dimensión oculta del ser a lo demoniaco, Descartes buscó refugio en un pensamiento calculador fundamentado en un Dios veraz que garantiza (...) la disponibilidad del ser. El análisis de los sueños aquí propuesto busca llamar la atención sobre un trasfondo que ayude a comprender de qué busca refugio Descartes cuando construye el edificio de la ciencia y qué vías quedan abiertas en el subsuelo de su pensamiento. (shrink)

En el presente artículo se trata de ofrecer una visión global de la concepción husserliana del inconsciente. A tal fin se va mostrando como los análisis estáticos, genéticos y generativos van desvelando diversos estratos que actúan de espaldas a la conciencia despierta. La inatención acompaña esencialmente intención, así como la ausencia es inseparable de la presencia. Lejos de ser transparente a sí, la conciencia deviene desde un fondo inconsciente y, lejos de ser unitaria, es inseparable de una Ich-Spaltung que habilita (...) el canal de parto a partir del cual deviene la vivencia. (shrink)

This paper deals with the interpretation and distribution of universal Free Choice (FC) items, such as English FC any or Spanish cualquiera. Crosslinguistically, universal FC items can be characterized as follows. First, they have a restricted distribution. Second, they express freedom of choice: the sentence You can take any card conveys the information that the addressee is free to pick whichever card she chooses. Under standard assumptions, the truth conditions of sentences like You can take any card are taken to (...) be captured by formalizations in which a universal quantifier ranging over individuals has wide scope over the possibility modal. The crucial observation that informs the account in this paper is that this type of formalization cannot capture the freedom of choice component. I will argue that in order to derive the right interaction between possibility modals and FC items, we need to add an exclusiveness condition to the standard wide scope paraphrases. The same proposal that guarantees freedom of choice will automatically account for the distribution restrictions of FC items. The formal implementation of this proposal is cast in the Hamblin semantics proposed in Kratzer and Shimoyama (Indeterminate phrases: The view from Japanese, 2002). (shrink)

This study examines the relationship between cooperative business relations in small businesses and environmental protection, one of the most important policies of social responsibility in manufacturing. We reviewed the literature and carried out an empirical study of 930 small manufacturing firms in Spain. Results indicate that small businesses that maintain and improve their cooperative relations through business networking with universities, competitors, suppliers and customers spend more on environmental protection. The managerial, practical, research and policy implications of the obtained research findings (...) are discussed. (shrink)

In this paper we analyze some of the major difficulties of informed consent. We consider insufficient to base IC on the principle of autonomy. We must not forget that the patient may be in a situation of extreme vulnerability and the good doctor should assume a degree of commitment and responsibility with his/her decisions. Our aim is to introduce the ethics of responsibility of Levinas in practice and theory of IC in order to generate a beneficent medical practice in which (...) the supervision and overseeing of the patient do not undermine his/her autonomy. (shrink)

This practical-theological study aims to develop a contextual theology in the areas of business and government that will aid a successful intervention by the church in diminishing the corrupt practices prevalent in South Africa. It seeks to prove that corruption is a major factor in causing the delays experienced in the implementation of service delivery, and that this is causing much anger and increasing disillusionment with the present system of democratic government. At the moment the church has a window of (...) opportunity for this intervention to take place, since many of those responsible for supporting, organising and implementing service delivery, both in government and industry, worship regularly, as committed members, in local Christian congregations. A modified application of the Asset-Based Community Development (ABCD) approach using focus groups is suggested as both a tool for intervention and for further research. (shrink)

The by now famous exclusion problem for mental causation admits only one possible solution, as far as I can see, namely: that mental and physical properties are linked by a vertical relation. In this paper, starting from what I take to be sensible premises about properties, I will be visiting some general relations between them, in order to see whether, first, it is true that some vertical relationship, other than identity, makes different sorts of causation compatible and second, whether physical (...) and mental properties can be pairs of such relationship. (shrink)

I apply recent research on the links between belief, truth and pragmatism based on Williams statement that “beliefs aim at truth,” to the phenomenon of pluralistic ignorance, in which agents act contrary to their private beliefs because they believe that other agents believe the contrary. I consider three positions; an epistemic position, a pragmatic position, and a third position coordinating the first two. I apply them to pluralistic ignorance while considering the recent study of Bjerring, Hansend and Pedersen. I conclude (...) that a purely epistemic approach is better for understanding pluralistic ignorance. (shrink)

Nota crítica sobre PornoXplotación: la explosión de la gran adicción de nuestros tiempos, de Mabel Lozano y Pablo J. Conellie, Barcelona, Editorial Alrevés, 2020, 286 pp.

SummaryA conception of numerical identity is introduced which, in accordance with a transcendental or imposition view of language, treats an identity predicate as having an ontologically generative function by genuinely being involved in the generation or construction of its domain of discourse. The proposed conception also allows for a plurality of identity predicates, each of which generating a domain, and it allows for the possibility that some such domains may not be unifiable with each other. All of these informal notions (...) are explicated in formal terms. Finally, a comparison to Scott and Fourman's intuitionistic conception of identity is made. (shrink)

Based on an idea of Ajdukiewiu, a method of equifunctionality is developed to provide a formal explication of the notion of sameness of use relative to some system of rules. Given this, a set‐theoretic explication of Lauener's context dependent conception of synonymy is introduced by looking at languages of ropositional logic, and compared both with Ajdukiewicz's original conception and with Carnap's explication of synonymy based on his method of extension and intention.

A partir de dos poemas de Borges se emprende un análisis de la experiencia del instante, inicialmente al trasluz de la crítica hegeliana de la inmediatez sensible como decir inconsciente, para, después, trasponerla al vacío constitutivo de la identidad que destapa el deseo, empresa que conduce hasta un fenómeno del presente como diástasis que depara la presencia de la ausencia.

Besides their cardinal and proportional readings, many and few have been argued to allow for a ‘reverse’ proportional reading that defies the conservativity universal. Recently, an analysis has been developed that derives the correct truth conditions for this reading while preserving conservativity. The present paper investigates two predictions of this analysis, based on two key ingredients. First, many is decomposed into a determiner stem many and the degree operator POS. This predicts that other elements may scopally intervene between the two (...) parts. Second, non-reverse and reverse readings arise from the versatile association possibilities of POS, as independently witnessed in the grammar. In languages in which the same versatile association profile is granted to the superlative degree operator -est, reverse readings are expected to arise for most as well. Both predictions are borne out. (shrink)

El texto aborda uno de los temas de la violencia contemporánea, la violencia política de las mujeres. A partir de los problemas para nombrar la violencia y de los análisis de A. Cavarero sobre el «horrorismo», se centra en dos casos: la muerte de Yoyes y las mujeres bombas suicidas chechenas, mostrando las construcciones sociales y culturales de sexo/género, sus mitos y estereotipos, en cuanto constituyen una de las raíces más profundas y persistentes de la violencia. En definitiva, de lo (...) que se trata es de reflexionar y comprender la vulnerabilidad de la condición humana. (shrink)

Dentro de la sociología francesa actual, Gilles Lipovetsky se ha convertido de forma paulatina en uno de los sociólogos con mayor proyección internacional, con sus finos análisis sobre las sociedades postmodernas. En este artículo se plantea una revisión crítica de las principales líneas argumentativas que expone el autor francés. El objetivo es el de reflexionar sobre las limitaciones de su aproximación a los conceptos de postmodernidad, hipermodernidad, y consumo.

Este trabajo tiene por objeto el estudio del bien jurídico de la libre competencia en el mercado como posible bien jurídico digno de tutela penal. Al respecto se plantean dos problemas esenciales: el propio concepto de competencia y el respeto a los principios legitimadores del Derecho penal. Para no argumentar en abstracto, se analiza un problema político-criminal concreto: el delito de corrupción entre particulares como delito contra la competencia en el mercado. El trabajo concluye que el legislador ha ignorado parcialmente (...) el principio de intervención mínima en este ámbito. (shrink)

Este artículo trata de mostrar cómo la fenomenología husserliana fue desplegando progresivamente el campo fenomenológico. Ese proceso llevó en las Investigaciones lógicas a aunar lo categorial y lo sensible. Más adelante, los análisis de la conciencia interna del tiempo llevaron tanto a abrir lo dado en la presencia a horizontes pro-re-tencionales, como a introducir la relación ego-alter ego y consciente-inconsciente en tanto que constitutivas de la trascendencia del objeto. De ese modo, el despliegue fenomenológico acabará despejando, en el marco genético (...) de una intersubjetividad intermonádica, el mundo que, en un primer momento, la epojé había puesto entre paréntesis. (shrink)

La presente investigación se efectuó con el objetivo de evaluar el impacto de la introducción y generalización del resultado científico: La educación en valores mediante la aplicación de medios de enseñanza - aprendizaje en la disciplina de Morfofisiología en la Licenciatura en Enfermería, a través de indicadores diseñados de acuerdo a las particularidades de la investigación. Se aplicaron encuestas, se realizó una revisión documental de bibliografía relacionada con la temática y de documentos de los departamentos e instituciones en que ha (...) incidido este resultado, lo cual permitió constatar la amplia y efectiva aplicación práctica de los resultados obtenidos de forma sistemática, a través de publicaciones, posgrados, presentación en eventos científicos y su generalización en diversas instituciones educacionales. This research was conducted with the objective of assessing the impact of the introduction and generalization of the scientific result: Values education through the application of teaching aids- learning in Morphophysiology subject in the Nursing Degree through indicators designed according to the research characteristics. Surveys were carried, furthermore, a documentary bibliographic review related to the subject matter and a review of documents from departments and institutions affected by this result were made. They enabled to verify the wide and effective practice of the results got in a systematic way, through publications, postgraduate courses and presentations in scientific events as well as its generalization in different educational institutions. (shrink)