The author starts from the traditional American notion that technology might offer a way to decrease the horror and suffering of warfare. He points out that historically this assumption is flawed in that past technological advances, from gunpowder weapons to bombers, have only made warfare more--not less--bloody. With a relentless logic, Colonel Dunlap takes to task those who say that the Revolution in Military Affairs has the potential to make war less bloody. He covers the technological landscape from precision-guided munitions (...) and Information Warfare to the use of space for military operations to raise issues that could pose difficult ethical, legal and moral problems for statesmen and soldiers. Some of these conundrums are so confounding that the author could claim that in all humility his only purpose was to raise these issues to prompt debate. But Colonel Dunlap takes the next step to outline several broad thematic avenues that may help us all address the difficult problems that lie ahead. (shrink)

Memory exhibits episodic superposition, an analog of the quantum superposition of physical states: Before a cue for a presented or unpresented item is administered on a memory test, the item has the simultaneous potential to occupy all members of a mutually exclusive set of episodic states, though it occupies only one of those states after the cue is administered. This phenomenon can be modeled with a nonadditive probability model called overdistribution (OD), which implements fuzzy-trace theory's distinction between verbatim and gist (...) representations. We show that it can also be modeled based on quantum probability theory. A quantum episodic memory (QEM) model is developed, which is derived from quantum probability theory but also implements the process conceptions of global matching memory models. OD and QEM have different strengths, and the current challenge is to identify contrasting empirical predictions that can be used to pit them against each other. (shrink)

Werner syndrome is a rare autosomal recessive disorder that mimics some of the characteristics of aging. The gene for this disorder has recently been identified as a helicase of the recQ subclass(1). Other phenotypically distinctive disorders caused by different helicase mutations include Bloom syndrome, Cockayne syndrome, xeroderma pigmentosum and trichothiodystrophy. Possible mechanisms by which helicases might produce the variable phenotypes are discussed. These include altered nucleotide excision repair and RNA polymerase II‐mediated transcription. The discovery of the helicase defect in Werner (...) syndrome provides a road map for future study of its unique pathogenesis and conceivable, but unproved, relationship to the aging process. (shrink)

Louis Frédéric Ancillon was a member of the Prussian Academy of Sciences and Belles Lettres whose imagined dialogue between Berkeley and Hume was read to the Academy in 1796 and published in 1799. It is important as an indicator of the reception of Hume and Berkeley in francophone philosophical circles in late eighteenth-century Prussia. Our introduction is followed by an English translation with notes.

Since the publication of Husserl's Logische Untersuchungen at the outset of this century, the notion of phenomenology has had a long and important history on the European continent. Of the many claims made on its behalf perhaps the most interesting is that phenomenology is able to ground philosophical assertions in a manner which is neither purely formal nor purely empirical, i.e., that phenomenology as a method is capable of transcending this very distinction. For example, phenomenologists argue that their reduction of (...) essences provides a way of knowing which is neither analytic nor synthetic but both. Having reached such an eidetic intuition phenomenologists claim to have attained a non-trivial universality and necessity. (shrink)

Aristotle assesses as valid three first figure syllogisms, each of which contains at least one premiss expressing a de re contingency. In fact, all three of these moods (namely, Barbara-QQQ, Barbara-XQM, and Barbara-LQM) are invalid. Utilizing the concept of ampliation, this paper shows how the mood Barbara-QQQ must be refined if it is to be deemed valid. It can then become clear as to how Barbara-XQM and Barbara-LQM can be disambiguated and ultimately validated. In treating all three moods, some theses (...) from S4 will be exploited in the context of distinguishing de dicto and de re modes of attributing possibility and necessity. Various Aristotelian propositional forms and rules of inference, including argumentation by ecthesis, will shape the presentation. The viability of Aristotle’s views on the convertibility of universal negative apodeictic propositions will emerge as decisive in evaluating the success of his modal syllogistic. (shrink)

Alfred Loisy and Maude Petre, like others who were associated with the Modernist movement in the Roman Catholic Church, shared hopes in a renewed Catholicism that would bring it into a positive relationship with modernity. With the Vatican condemnation of Modernism in 1907, Loisy abandoned all optimism for viable reform in the Church, and instead looked forward to a Religion of Humanity. While Petre found Loisy's ideal attractive, she retained a hope that the Church would undergo renewal at some future (...) point. Each of them had to come to terms with a dark side of modernity that emerged with the Great War. Loisy's Guerre et religion and Petre's Reflections of a Non-Combatant preserve a record of their struggles to preserve their faith in modernity and in humanity. (shrink)

The Belmont Report’s distinction between research and the practice of accepted therapy has led various authors to suggest that these purportedly distinct activities should be governed by different ethical principles. We consider some of the ethical consequences of attempts to separate the two and conclude that separation fails along ontological, ethical, and epistemological dimensions. Clinical practice and clinical research, as with yin and yang, can be thought of as complementary forces interacting to form a dynamic system in which the whole (...) exceeds the sum of its parts. Just as effective clinical practice cannot exist without clinical research, meaningful clinical research requires the context of clinical practice. We defend this thesis by triangulation, that is, by outlining how multiple investigators have reached this conclusion on the basis of varied theoretical and applied approaches. More confidence can be placed in a result if different methods/viewpoints have led to that result. (shrink)

From a moral-philosophical standpoint, the convergence and strengthening of two interlocking ideological developments since the mapping of the human genome in 2001 would seem significant and thus call for vigilance. One of these stems from advances in biogenetic technology and brain research; the other posits evolutionary biology as the comprehensive explanation and origin of the human moral impulse as well as the universe. Both conceptual frameworks are rooted in the assumptions of metaphysical materialism. Whether human morality can be plausibly ascribed (...) to biology—regardless of its support from neuroscience, genomic technology or evolutionary psychology—and whether physical science per se is adequate to make metaphysical pronouncements will require a reasoned response in the second decade of the twenty-first century. At stake is no less than “civil society” itself and whether human beings in fact can be held responsible for their actions. (shrink)