Recently, scholars have looked more closely at the philosophical importance of the imaginative and literary aspects of Plato's writing, and have begun to appreciate the methods of ancient philosophers and commentators who studied Plato. This study brings together leading philosophical and literary scholars to investigate these new-old approaches.

Two classic theories maintain that aging evolves either because of alleles whose deleterious effects are confined to late life or because of alleles with broad pleiotropic effects that increase early‐life fitness at the expense of late‐life fitness. However, empirical studies often reveal positive pleiotropy for fitness across age classes, and recent evidence suggests that selection on early‐life fitness can decelerate aging and increase lifespan, thereby casting doubt on the current consensus. Here, we briefly review these data and promote the simple (...) argument that aging can evolve under positive pleiotropy between early‐ and late‐life fitness when the deleterious effect of mutations increases with age. We argue that this hypothesis makes testable predictions and is supported by existing evidence. (shrink)

The problem, as Augustine sees it, is to show how it is possible both that we voluntary will to perform certain actions and that God foreknows that we shall will to perform these actions. The argument which gives rise to this problem may be expressed as follows.

So van Leeuwen prints the lines, following Cobet and Meineke in athetizing 16. Nor is it difficult to find grounds for the exclusion; τòν πο is repeated at 47; the following three words smell of the scholiast; the last three resemble the end of 13. The line taken as a whole seems to play little if any role, and indeed to lack meaning, even if line 47 is some way away and it is a little odd that the three separate (...) elements meld into a perfectly acceptable comic trimeter . Conjectures are not lacking for the replacement of κ τν ρνων by something which gives more sense; Köchly's νθρωποσ ποτ' ὢν may be taken as typical in both meaning and style. (shrink)

The feeling that one was ‘born in the wrong time’ we call malchronia. This is distinct from mere nostalgia, in that it may generate the longing to transcend the temporal present in favor of a time of which one has had no experience, or even a timeless state of being. Implicit in malchronetic longing is the rejection of one’s experience of one’s own time, making it a revolutionary and utopian inclination. In this article we examine two dominant strategies—primitive weapons in (...) the war on time, really—that have been developed in the hopes of delivering individuals to a future beyond the reach of their natural life spans: cryonics and bionics. (shrink)

This book is unique because it is the first single-author monograph which applies Bourdieu’s theory to management studies. It takes a theory-driven approach to develop models to describe service innovation. This will give the reader a full understanding of the variety of different theoretical concepts that Bourdieu created and used and how they can be applied to the study of management and innovation. Moreover, it is also the only book that links Bourdieu’s theory to his methodological approach, providing the reader (...) with a toolkit of methods to perform business ethnographies according to Bourdieu’s approach. The book acts as a primer for anyone wanting to learn how to model an organisational system from a Bourdieusian perspective. It contains all the information someone might need to begin to go out in the field and collect data. Consequently, the people that might want to read this publication include post-graduate students looking to learn business anthropology, as well as post-doctoral and other early career researchers. (shrink)

The synergies between viral and bacterial infections are well established. Most studies have been focused on the indirect mechanisms underlying this phenomenon, including immune modulation and alterations to the mucosal structures that promote pathogen outgrowth. A growing body of evidence implicates direct binding of virus to bacterial surfaces being an additional mechanism of synergy at the host–pathogen interface. These cross‐kingdom interactions enhance bacterial and viral adhesion and can alter tissue tropism. These bacterial–viral complexes play unique roles in pathogenesis and can (...) alter virulence potential. The bacterial–viral complexes may also play important roles in pathogen transmission. Additionally, the complexes are recognized by the host immune system in a distinct manner, thus presenting novel routes for vaccine development. These synergies are active for multiple species in both the respiratory and gastrointestinal tract, indicating that direct interactions between bacteria and virus to modulate host interactions are used by a diverse array of species. (shrink)

Unlike some psychiatric illnesses, criminal lifestyles are not reproductive dead ends and may represent frequency-dependent adaptations. Sociopaths may gain reproductively from their greater relative to nonsociopaths. This mating-effort construct should be assessed directly in future studies of sociopathy. Collaboration between biologically oriented and environmentally oriented researchers is needed to investigate the biosocial basis of sociopathy.