Background Ensuring individual free and informed decision‐making for research participation is challenging. It is thought that preliminarily informing communities through ‘community sensitization’ procedures may improve individual decision‐making. This study set out to assess the relevance of community sensitization for individual decision‐making in research participation in rural Gambia. Methods This anthropological mixed‐methods study triangulated qualitative methods and quantitative survey methods in the context of an observational study and a clinical trial on malaria carried out by the Medical Research Council Unit Gambia. (...) Results/discussion Although 38.7% of the respondents were present during sensitization sessions, 91.1% of the respondents were inclined to participate in the trial when surveyed after the sensitization and prior to the informed consent process. This difference can be explained by the informal transmission of information within the community after the community sensitization, expectations such as the benefits of participation based on previous research experiences, and the positive reputation of the research institute. Commonly mentioned barriers to participation were blood sampling and the potential disapproval of the household head. Conclusion Community sensitization is effective in providing first‐hand, reliable information to communities as the information is cascaded to those who could not attend the sessions. However, further research is needed to assess how the informal spread of information further shapes people's expectations, how the process engages with existing social relations and hierarchies (e.g. local political power structures; permissions of heads of households) and how this influences or changes individual consent. (shrink)

It is widely held that quantum mechanics is the first scientific theory to present scientifically internal, fundamental difficulties for a realistic interpretation (in the philosophical sense). The standard (Copenhagen) interpretation of the quantum theory is often described as the inevitable instrumentalistic response. It is the purpose of the present article to argue that quantum theory doesnot present fundamental new problems to a realistic interpretation. The formalism of quantum theory has the same states—it will be argued—as the formalisms of older physical (...) theories and is capable of the same kinds of philosophical interpretation. This result is reached via an analysis of what it means to give a realistic interpretation to a theory. The main point of difference between quantum mechanics and other theories—as far as the possibilities of interpretation are concerned—is the special treatment given tomeasurement by the “projection postulate.” But it is possible to do without this postulate. Moreover, rejection of the projection postulate does not, in spite of what is often maintained in the literature, automatically lead to the many-worlds interpretation of quantum mechanics. A realistic interpretation is possible in which only the reality ofone (our) world is recognized. It is argued that the Copenhagen interpretation as expounded by Bohr is not in conflict with the here proposed realistic interpretation of quantum theory. (shrink)

Inappropriate authorship is a common problem in biomedical research and may be becoming one in bioethics, due to the increase in multiple authorship. This paper investigates the authorship policies of bioethics journals to determine whether they provide adequate guidance for researchers who submit articles for publication, which can help deter inappropriate authorship. It was found that 63.3% of bioethics journals provide no guidance on authorship; 36.7% provide guidance on which contributions merit authorship, 23.3% provide guidance on which contributions do not (...) merit authorship, 23.3% require authors to take responsibility for their contributions or for the article as a whole, 20% provide guidance on which contributions merit an acknowledgement but not authorship, 6.7% require authors to describe their contributions, and only 3.3% distinguish between authorship in empirical and conceptual research. To provide authors with effective guidance and promote integrity in bioethics research, bioethics journals should adopt authorship policies that address several important topics, such as the qualifications for authorship, describing authorship contributions, taking responsibility for the research and the difference between authorship in empirical and conceptual research. (shrink)

From the first months of life, human infants produce “protophones,” speech-like, non-cry sounds, presumed absent, or only minimally present in other apes. But there have been no direct quantitative comparisons to support this presumption. In addition, by 2 months, human infants show sustained face-to-face interaction using protophones, a pattern thought also absent or very limited in other apes, but again, without quantitative comparison. Such comparison should provide evidence relevant to determining foundations of language, since substantially flexible vocalization, the inclination to (...) explore vocalization, and the ability to interact socially by means of vocalization are foundations for language. Here we quantitatively compare data on vocalization rates in three captive bonobo (Pan paniscus) mother–infant pairs with various sources of data from our laboratories on human infant vocalization. Both humans and bonobos produced distress sounds (cries/screams) and laughter. The bonobo infants also produced sounds that were neither screams nor laughs and that showed acoustic similarities to the human protophones. These protophone-like sounds confirm that bonobo infants share with humans the capacity to produce vocalizations that appear foundational for language. Still, there were dramatic differences between the species in both quantity and function of the protophone and protophone-like sounds. The bonobo protophone-like sounds were far less frequent than the human protophones, and the human protophones were far less likely to be interpreted as complaints and more likely as vocal play. Moreover, we found extensive vocal interaction between human infants and mothers, but no vocal interaction in the bonobo mother–infant pairs—while bonobo mothers were physically responsive to their infants, we observed no case of a bonobo mother vocalization directed to her infant. Our cross-species comparison focuses on low- and moderate-arousal circumstances because we reason the roots of language entail vocalization not triggered by excitement, for example, during fighting or intense play. Language appears to be founded in flexible vocalization, used to regulate comfortable social interaction, to share variable affective states at various levels of arousal, and to explore vocalization itself. (shrink)

This is part of a three-volume collection of most of David Lewis' papers in philosophy, except for those that previously appeared in his Philosophical Papers (Oxford University Press, 1983 and 1986). They are now offered in a readily accessible form. This second volume is devoted to Lewis' work in metaphysics and epistemology. The purpose of this collection, and the volumes that precede and follow it, is to disseminate more widely the work of an eminent and influential contemporary philosopher. The volume (...) will serve as a useful work of reference for teachers and students of philosophy. (shrink)

In philosophical interpretations of the Laozi the function of the ‘sage’ is a relatively under concentrated on topic. Although nearly every scholar does have something to say about the sage, comments are usually brief and often revolve around the sage as some particular character-type; for example highlighting the sage as a ‘sage-ruler’. In this article we will argue that the sage serves as a tool for understanding the major concepts, thinking, and logic of the Laozi. While the sage does often (...) refer to the sage-ruler this does not mean all references are politically orientated, and even those that are can easily be applied to a host of social situations. This paper thus seeks to appreciate the context for what the Laozi says by looking at how the text itself envisions the embodiment of its ideas through reference to the sage. (shrink)

D. H. Mellor; VI*—I and Now, Proceedings of the Aristotelian Society, Volume 89, Issue 1, 1 June 1989, Pages 79–94, https://doi.org/10.1093/aristotelian/89.1.79.

Perforation or gap formation in a vegetation is a major process in landscape transformation. The occurrence of gaps profoundly alters the microclimatical conditions in a vegetation. A method is proposed to quantify perforation by using the three main 2-D characteristics of the gaps: area, number and boundary length. New measures are developed by normalizing the observed values to the reference status of minimum and maximum perforation. As minimum perforation status, the presence of one single gap with area equal to the (...) map resolution is assumed. The new measures are combined using a 3-D Euclidean distance to visualize the process and to detect changes. The method is exemplified using a field case of gaps in a tropical terra firme rainforest at Tiputini, Ecuador. (shrink)

There is a common view in medical ethics that the patient's right to be informed entails, as well, a correlative right not to be informed, i.e., to waive one's right to information. This paper argues, from a consideration of the concept of autonomy as the foundation for rights, that there can be no such ‘right’ to refuse relevant information, and that the claims for such a right are inconsistent with both deontological and utilitarian ethics. Further, the right to be informed (...) is shown to be a mandatory right (though not a welfare right); persons are thus seen to have both a right and a duty to be informed. Finally, the consequences of this view are addressed: since the way in which we conceptualize our problems tends to determine the actions we take to resolve them, it is important properly to conceptualize patients' requests not to be informed. There may be many reasons for acting in accord with such a request, but it is a mistake to conceptualize one's act as ‘respecting a right possessed by persons’. Keywords: medical ethics, informed consent, autonomy, information-waivers, rights, obligations CiteULike Connotea Del.icio.us What's this? (shrink)

This article proposes a semio-rhetorical epistemology for visual documents, one capable of accounting for both their internal configuration, which we shall call the compositional dimension, and their persuasive force within public space, or their rhetorical dimension. The field of reference will be that of identity-related images on social networks, because compared to other kinds of images, such as artistic or professional ones, they adopt new compositional solutions and new dynamics of circulation. To test this theoretical framework, we will conduct an (...) analysis which has never been carried out in semiotics and which, as far as we know, remains very rare even in the overall field of visual studies, that is, the analysis of the profile of an Instagram influencer’s visual production, that of Canadian artist Rupi Kaur. Taking into account the flow of images shared over time, we will focus primarily on the compositional dimension that articulates the specificity of the language of images. The most appropriate model for investigating social network photos seems to be that of the portrait, thanks to which we will identify a first series of regularities and deviations. Secondly, we will turn towards the rhetorical dimension – the persuasive strategies found within, through, and towards images – focusing on the analysis of a single photo: on the one hand, it is a shot which presents greater compositional richness than others; on the other hand, it has greatly impacted the notoriety of the influencer, due to the censorship incurred on Instagram, its abundant coverage by traditional media, and the heated debate it triggered on social media. We will thus propose a reinterpretation of Paul Ricœur’s theory of identity in order to balance the rhetorical and the compositional dimensions through a unitary theoretical hypothesis. Visual identity on social networks is always the result of a negotiation between two opposite tendencies: on the one hand, the experiential pressure expressed through images related to the body and everyday practices; on the other, the algorithmic pressure due to the delegation of the management of identity to software. The case of Rupi Kaur is a rare example of a critical mediation between these two pressures and helps us build a methodology for the examination of images belonging to other social domains. (shrink)

Chez les commentateurs platoniciens de l’époque impériale, l’un des problèmes majeurs liés à la théorie des Idées concernait le domaine d’application de cette doctrine. L’exégèse de la première partie du Parménide de Platon donnait occasion à diverses discussions sur ce sujet. Le Commentaire de Proclus sur le Parménide est sans doute la plus précieuse source qui soit parvenue de l’Antiquité jusqu’à nous pour la reconstitution de ces débats. Alors que la grande majorité des commentateurs anciens étaient convaincus que les Idées (...) ont un domaine assez restreint, le Commentaire de Proclus nous révèle l’existence d’une lecture alternative, selon laquelle il y a des Idées de « toutes choses ». Proclus relie cette interprétation alternative en particulier à l’existence des Idées de choses mauvaises et d’individus, probablement parce que ces deux classes d’objets étaient vraiment les dernières choses dont un platonicien orthodoxe voudrait admettre des Idées. Amélius est le seul néoplatonicien connu pour avoir soutenu l’existence des Idées de choses mauvaises. Dans cet article j’essaie de montrer que, selon toute vraisemblance, Amélius est également la cible de la réfutation des Idées d’individus par Proclus dans son Commentaire. La conclusion qui s’ensuit naturellement est qu’Amélius était très probablement l’un de ces philosophes qui, d’après Proclus, admettaient des Idées « de toutes choses ». (shrink)

In Bester’s article (2018) challenging the use of the harm principle and advocating sole reliance on the use of a best interest standard (BIS) in pediatric decision-making, we believe that the auth...

A laboratory-testable, solid-state Maxwell demon is proposed that utilizes the electric field energy of an open-gap p-n junction. Numerical results from a commercial semiconductor device simulator (Silvaco International–Atlas) verify primary results from a 1-D analytic model. Present day fabrication techniques appear adequate for laboratory tests of principle.

It is often thought that instances of the T-schema such as snow is white is true if and only if snow is white state correspondences between sentences andthe world, and that therefore such sentences play a crucial role in correspondence theories oftruth. I argue that this assumption trivializes the correspondence theory: even a disquotationaltheory of truth would be a correspondence theory on this conception. This discussionallows one to get clearer about what a correspondence theory does claim, and toward the end (...) of thepaper I discuss what a true correspondence theory of truth would involve. (shrink)

Objectives: To describe the concerns and priorities of key stakeholders in a developing country regarding ethical obligations held by researchers and perceptions of equity or “what is fair” for study participants in an HIV/AIDS clinical drug trial. Design: Qualitative study with focus groups. Setting: Teaching and referral hospital and rural health centre in western Kenya. Participants: Potential HIV/AIDS clinical trial participants, clinician researchers, and administrators. Results: Eighty nine individuals participated in a total of 11 focus groups over a four month (...) period. The desire for continued drug therapy, most often life long, following an HIV/AIDS clinical trial was the most common priority expressed in all focus groups. Patients with and without HIV/AIDS also thought subsidisation of drug therapies and education were critical forms of compensation for clinical trial participation. Financial incentives were considered important primarily for purchasing drug therapy as well as obtaining food. Patients noted a concern for the potential mismanagement of any money offered. Clinician researchers and administrators felt strongly that researchers have a moral obligation to participants following a trial to provide continued drug therapy, adverse event monitoring, and primary care. Finally, clinician researchers and administrators stressed the need for thorough informed consent to avoid coercion of study participants. Conclusions: Kenyan patients, clinician researchers, and administrators believe that it would be unfair to stop antiretroviral therapy following an HIV/AIDS clinical trial and that researchers have a long term obligation to participants. (shrink)

This study aimed to determine if people would use social usefulness as a criterion when allocating a kidney to potential recipients. Participants ranked hypothetical patients in order of priority to receive the kidney, using only information on the patients’ volunteering record, intelligence, emotional intelligence, and attractiveness. The results showed that volunteers were prioritized over nonvolunteers, highly intelligent patients over those with average intelligence, patients with high emotional intelligence over those with average emotional intelligence, and good-looking patients over average-looking patients. There (...) was little evidence of personal favoritism. Implications and limitations are discussed. (shrink)

Idealism is often associated with the kind of metaphysical system building which was successfully disposed of by logical positivism. As Hume's fork was intended to deliver a serious blow to Leibnizian metaphysics so logical positivism invoked the verificationist principle against the reawakening of metaphysics, in the tradition of German and British idealism. In the light of this one might reasonably wonder what Carnap's pragmatism could possibly have in common with Collingwood's idealism. After all, Carnap is often seen as a champion (...) of the logical positivist's critique of metaphysics, whilst Collingwood is renowned for his defence of the possibility of metaphysics against the attack to which Ayer subjected it. The answer is that they have more in common than one might suspect and that, once the relevant qualifications are made, there is as much convergence as there is contestation between Carnapian pragmatism and Collingwoodian idealism. (shrink)

It is almost universally believed that in quantum theory the two following statements hold: all transformations are achieved by a unitary interaction followed by a von-Neumann measurement; all mixed states are marginals of pure entangled states. I name this doctrine the dogma of purification ontology. The source of the dogma is the original von Neumann axiomatisation of the theory, which largely relies on the Schrődinger equation as a postulate, which holds in a nonrelativistic context, and whose operator version holds only (...) in free quantum field theory, but no longer in the interacting theory. In the present paper I prove that both ontologies of unitarity and state-purity are unfalsifiable, even in principle, and therefore axiomatically spurious. I propose instead a minimal four-postulate axiomatisation: associate a Hilbert space \ to each system \; compose two systems by the tensor product rule \; associate a transformation from system \ to \ to a quantum operation, i.e. to a completely positive trace-non-increasing map between the trace-class operators of \ and \; evaluate all joint probabilities through that of a special type of quantum operation: the state preparation. I then conclude that quantum paradoxes—such as the Schroedinger-cat’s, and, most relevantly, the information paradox—are originated only by the dogma of purification ontology, and they are no longer paradoxes of the theory in the minimal formulation. For the same reason, most interpretations of the theory interpret the same dogma, not the strict theory stripped of the spurious postulates. (shrink)

SummaryThe crux of Quine's argument against synonymy— and therewith for a version of pragmatism, and independent/y against mentalism — is his challenge to the other side to explain the behavioural difference between the disposition to employ two predicates, say, interchangeably because of habitually “believing“ them coextensive, and the disposition to do so because of “meaning” the same by each. Since synonymy is taught behaviourally, the distinction in question must make a difference behaviourally, but not necessarily one explainable wholly non‐mentalistically. The (...) distinction is drawn in terms of what would extinguish the disposition. The resultant concept of cognitive synonymy is then used to clarify the difference between trivial and non‐trivial necessary truth, and explain how logical deduction by tautological steps can lead to new knowledge.RésuméLe noeud de I'argumentation de Quine contre la synonymie— et donc pour une version de pragmatisme et indépendamment contre le mentalisme — réside dans le défi lancéà la partie adverse d'expliquer en termes de comportement la différence entre d'une part la disposition à utiliser deux prédicats de façon »interchangeable« parce qu'on les »tcroit« habituellement coextensifs, et d'autre part la disposition à le faire parce que l'un et l'autre »signifiant« la même chose. Puisque la synonymie est prise dans un sens comportemental, cette distinction doit se manifester par une différence de comportement, mais n'est pas nécessairement totalement explicable sans recourir au mental. La distinction est faite en considérant ce qui supprimerait la disposition à les utiliser de façon interchangeable. Le concept de “lsynonymie cognitive” qui se dégage de cette analyse est ensuite utilisé pour clarifier la différence entre des várités nécessaires triviales et non triviales et pour expliquer comment une deduction logique par pas tautologiques peut conduire à des connaissances nouvelles.ZusammenfassungDer entscheidende Punkt in Quines Argument gegen die Synonymitrtt— und damit für eine bestimmte Version des Pragmatismus und unabhängig davon gegen den Mentalismus — ist seine Aufforderung, den verhaltensmässigen Unterschied zu erklaen zwischen einerseits der Disposition, zwei Prädikate in austauschbarer Weise zu verwenden, weil man sie gewohnheitsmässig für Koextensiv hält, und andererseits der Disposition, dies zu tun, weil sie gleiche »Bedeutung« haben. Da die Synonymitlit behaviouristisch gelehrt und gelernt wird, muss die zur Diskussion stehende Unterscheidung verhaltensmässig einen Unterschied ausmachen, welcher jedoch nicht notwendigerweise ganz in nicht‐mentalistischer Termen erklärbar ist. Die Unterscheidung wird in Termen formuliert die die Disposition aufheben warden. Der Begriff der kognitiven Synonyrnitlft. der daraus resultiert, wird dann verwendet, urn den Unterschied zwischen trivialen und nicht‐trivialen notwendigen Wahrheiten zu erläutern und um zu erkläen, wie eine logische Deduktion durch tautologische Schritte zu neuem Wissen führen kann. (shrink)

D W Hamlyn; How Does Knowledge Start? A Reply to Pamela Moore, Journal of Philosophy of Education, Volume 15, Issue 1, 30 May 2006, Pages 137, https://doi.org/1.