"Complementing Harker's photographs are vignettes by poet and writer Jim Heynen. Both whimsical and endearing, each vignette treats barns as organic and intelligent entities, reflecting the living history that can be found inside each rural structure."--BOOK JACKET.

A documentary photographer captures the glory and decay of one of rural America's most elemental icons in this collection of images that encapsulate the dramatic transformations that have overtaken the Iowa countryside. Original.

For decades, cigarette companies helped to promote the impression that there was no scientific consensus concerning the safety of their product. The appearance of controversy, however, was misleading, designed to confuse the public and to protect industry interests. Created scientific controversies emerge when expert communities are in broad agreement but the public perception is one of profound scientific uncertainty and doubt. In the first book-length analysis of the concept of a created scientific controversy, David Harker explores issues including climate (...) change, Creation science, the anti-vaccine movement and genetically modified crops. Drawing on work in cognitive psychology, social epistemology, critical thinking and philosophy of science, he shows readers how to better understand, evaluate, and respond to the appearance of scientific controversy. His book will be a valuable resource for students of philosophy of science, environmental and health sciences, and social and natural sciences. (shrink)

The most influential arguments for scientific realism remain centrally concerned with an inference from scientific success to the approximate truth of successful theories. Recently, however, and in response to antirealists' objections from radical discontinuity within the history of science, the arguments have been refined. Rather than target entire theories, realists narrow their commitments to only certain parts of theories. Despite an initial plausibility, the selective realist strategy faces significant challenges. In this article, I outline four prerequisites for a successful selective (...) realist defence and argue that adopting a comparative sense of success both satisfies those requirements and partially in consequence provides a more compelling, albeit more modest, realist thesis. (shrink)

Scientific theories are developed in response to a certain set of phenomena and subsequently evaluated, at least partially, in terms of the quality of fit between those same theories and appropriately distinctive phenomena. To differentiate between these two stages it is popular to describe the former as involving the accommodation of data and the latter as involving the prediction of data. Predictivism is the view that, ceteris paribus, correctly predicting data confers greater confirmation than successfully accommodating data. In this paper, (...) I take issue with a variety of predictivist theses, argue that their role for issues of confirmation is extremely limited, and attempt to account for the appeal that predictivism has enjoyed. Introduction Temporal Predictivism Heuristic Predictivism Weak Predictivism 4.1 Inference to better theories 4.2 Inference to better methods Arguments for Strong Heuristic Predictivism 5.1 Best explanations argument 5.2 Conditional support 5.3 Unique explanations Increased Explanatory Unification 6.1 Explaining what other theories can't 6.2 Contrived hypotheses 6.2 Strength and simplicity Conclusions CiteULike Connotea Del.icio.us What's this? (shrink)

The judgment that a given event is epistemically improbable is necessary but insufficient for us to conclude that the event is surprising. Paul Horwich has argued that surprising events are, in addition, more probable given alternative background assumptions that are not themselves extremely improbable. I argue that Horwich’s definition fails to capture important features of surprises and offer an alternative definition that accords better with intuition. An important application of Horwich’s analysis has arisen in discussions of fine-tuning arguments. In the (...) second part of the paper I consider the implications for this argument of employing my definition of surprise. I argue that advocates of fine-tuning arguments are not justified in attaching significance to the fact that we are surprised by examples of fine-tuning. (shrink)

A not unpopular thesis, when it comes to the confirmation of scientific theories, is that data which were used in the construction of a theory afford poorer support for that theory than data that played no role. Some compelling thought experiments have been offered in favour of this view, not as proof but rather to add some intuitive plausibility. In this paper I consider such thought experiments and argue that they do not support the thesis; the perceived importance of prediction (...) over accommodation, at least in these cases, is illusory. Introduction Background assumptions Strong thesis Weak thesis Conclusions. (shrink)

The result of a seven-and-a-half-year undertaking to document Iowa's barns and all they represent, Harker's Barns: Visions of an American Icon featured seventy-five stunning black-and-white photographs by Michael Harker. An impressive and well-received collection, the book helped preserve the glory of one of rural America's most elemental icons. Still Standing, a postcard book of thirty of Harker's barn photographs---some from Harker's Barns, some previously unseen---continues that mission of preservation. Printed on heavy card stock and perforated for (...) easy removal, the cards showcase midwestern barns-from square to round, wood to brick, Dutch to Swedish, occupied or abandoned, all symbolizing a passing way of life that was once the lifeblood of Iowa and the Midwest. As barns continue to disappear, these images will endure. “Barns Again! Celebrating an American Icon,” an exhibit of Harker's barn photos sponsored by Humanities Iowa and organized by the Smithsonian Institution's Traveling Exhibition Service and the National Building Museum, with assistance from the National Trust for Historic Preservation, is currently touring Iowa. (shrink)

Most analytic epistemologists, foundationalists and coherentists alike, have rejected the possibility of an infinitely long, non-recurring regress of justified beliefs. it is instructive to inquire why this notion has received nearly universal condemnation. in a review of recent work six sorts of arguments against infinite justificatory chains are examined. it is concluded firstly that, while regresses in which each belief is justified solely via relations to further beliefs cannot exist, the impossiblity of other sorts of infinite justificatory chains has not (...) been shown, and secondly that there may nevertheless be sound methodological reasons for provisionally rejecting the infinite regress possibility while more satisfactory alternatives are explored. (shrink)

In a recent paper McCain (2012) argues that weak predictivism creates an important challenge for external world scepticism. McCain regards weak predictivism as uncontroversial and assumes the thesis within his argument. There is a sense in which the predictivist literature supports his conviction that weak predictivism is uncontroversial. This absence of controversy, however, is a product of significant plasticity within the thesis, which renders McCain’s argument worryingly vague. For McCain’s argument to work he either needs a stronger version of weak (...) predictivism than has been defended within the literature, or must commit to a more precise formulation of the thesis and argue that weak predictivism, so understood, creates the challenge to scepticism that he hopes to achieve. The difficulty with the former is that weak predictivism is not uncontroversial in the respect that McCain’s argument would require. I consider the prospects of saving McCain’s argument by committing to a particular version of weak predictivism, but find them unpromising for several reasons. (shrink)

The problem of demarcation continues to attract attention, in part because solutions are perceived to have enormous social significance. The civic motivation, however, I argue is in tension with the heterogeneity of the sciences. Philosophers of science would be better employed reflecting on the features, causes, and consequences, of created, scientific controversies. These arise when relevant experts are in broad agreement about what conclusions can sensibly be drawn from available evidence, but the public perceives an expert community deeply divided and (...) conclusions that are plagued by profound and systemic uncertainty. In the second part of the paper I explore this concept further. (shrink)

Several friends of inference to best explanation have claimed in recent work that explanatory virtues, such as consilience, simplicity and increased precision, play an important heuristic role in assigning probabilities to available hypotheses and that it is this role that justifies continued efforts to investigate the scope, nature and epistemic value of the inference rule. In this paper I argue that understanding explanatory virtues as a guide to probability assignments creates a critical dilemma for advocates of IBE that has not (...) previously been made sufficiently explicit and which has significant implications for the prospects of the rule. I conclude that the viability of IBE requires that explanatory virtues be related to a non - probabilistic conception of success. (shrink)

Inference to the best explanation has at times appeared almost indistinguishable from a rule that recommends simply that we should infer the hypothesis which is most plausible given available evidence. In this paper I argue that avoiding this collapse requires the identification of peculiarly explanatory virtues and consider Woodward's concept of invariance as an example of such a virtue. An additional benefit of augmenting IBE with Woodward's model of causal explanation is also suggested.

Inferences from scientific success to the approximate truth of successful theories remain central to the most influential arguments for scientific realism. Challenges to such inferences, however, based on radical discontinuities within the history of science, have motivated a distinctive style of revision to the original argument. Conceding the historical claim, selective realists argue that accompanying even the most revolutionary change is the retention of significant parts of replaced theories, and that a realist attitude towards the systematically retained constituents of our (...) scientific theories can still be defended. Selective realists thereby hope to secure the argument from success against apparent historical counterexamples. Independently of that objective, historical considerations have inspired a further argument for selective realism, where evidence for the retention of parts of theories is itself offered as justification for adopting a realist attitude towards them. Given the nature of these arguments from success and from retention, a reasonable expectation is that they would complement and reinforce one another, but although several theses purport to provide such a synthesis the results are often unconvincing. In this paper I reconsider the realist’s favoured type of scientific success, novel success, offer a revised interpretation of the concept, and argue that a significant consequence of reconfiguring the realist’s argument from success accordingly is a greater potential for its unification with the argument from retention.Keywords: Scientific realism; Pessimistic meta-induction; Success; Progress; Aether; Novelty. (shrink)

In this wide-ranging interview, Dave Elder-Vass discusses his main contributions to critical realist theory over two decades. In the first half, he explains his early work on emergence, agency, str...

This introduction to a special issue of Topoi introduces and summarises the relationship between three main varieties of 'enactivist' theorising about the mind: 'autopoietic', 'sensorimotor', and 'radical' enactivism. It includes a brief discussion of the philosophical and cognitive scientific precursors to enactivist theories, and the relationship of enactivism to other trends in embodied cognitive science and philosophy of mind.

We present a specific elaboration and partial defense of the claims that cognition is enactive, embodied, embedded, affective and (potentially) extended. According to the view we will defend, the enactivist claim that perception and cognition essentially depend upon the cognizer’s interactions with their environment is fundamental. If a particular instance of this kind of dependence obtains, we will argue, then it follows that cognition is essentially embodied and embedded, that the underpinnings of cognition are inextricable from those of affect, that (...) the phenomenon of cognition itself is essentially bound up with affect, and that the possibility of cognitive extension depends upon the instantiation of a specific mode of skillful interrelation between cognizer and environment. Thus, if cognition is enactive then it is also embodied, embedded, affective and potentially extended. (shrink)

Background The field of personal health monitoring (PHM) develops rapidly in different contexts, including the armed forces. Understanding the ethical dimension of this type of monitoring is key to a morally responsible development, implementation and usage of PHM within the armed forces. Research on the ethics of PHM has primarily been carried out in civilian settings, while the ethical dimension of PHM in the armed forces remains understudied. Yet, PHM of military personnel by design takes place in a different setting (...) than PHM of civilians, because of their tasks and the context in which they operate. This case study therefore focusses on obtaining insights into the experiences and related values of different stakeholders regarding an existing form of PHM, the Covid-19 Radar app, in the Netherlands Armed Forces. Methods We carried out an exploratory qualitative study, using semi-structured interviews with twelve stakeholders in the Netherlands Armed Forces. We focussed on participation in the use of PHM, reflections on the practical use and use of data, moral dilemmas and the need for ethics support, all in regard to PHM. The data was analysed using an inductive thematic approach. Results Three interlinking categories reflecting ethical dimensions of PHM emerged: (1) values, (2) moral dilemmas, and (3) external norms. The main values identified were: security (in relation to data), trust and hierarchy. Multiple related values were found. Some, but no broadly shared, moral dilemmas were identified and no strong need for ethics support was expressed. Conclusion This study shed light on key values, provide insights in the experienced and presumed moral dilemmas and bring to mind ethics support considerations when looking at PHM in the armed forces. Some values bring a certain vulnerability to military users when personal and organisational interests are not aligned. Furthermore, some identified values may hinder a careful consideration of PHM because they potentially conceal parts of ethical dimensions of PHM. Ethics support can assist in uncovering and addressing these concealed parts. The findings highlight a moral responsibility for the armed forces to devote attention to the ethical dimensions of PHM. (shrink)

Of two contending models for eukaryotic evolution the “archezoan“ has an amitochondriate eukaryote take up an endosymbiont, while “symbiogenesis“ states that an Archaeon became a eukaryote as the result of this uptake. If so, organelle formation resulting from new engulfments is simplified by the primordial symbiogenesis, and less informative regarding the bacterium‐to‐mitochondrion conversion. Gradualist archezoan visions still permeate evolutionary thinking, but are much less likely than symbiogenesis. Genuine amitochondriate eukaryotes have never been found and rapid, explosive adaptive periods characteristic of (...) symbiogenetic models explain this. Mitochondrial proteomes, encoded by genes of “eukaryotic origin“ not easily linked to host or endosymbiont, can be understood in light of rapid adjustments to new evolutionary pressures. Symbiogenesis allows “expensive” eukaryotic inventions via efficient ATP generation by nascent mitochondria. However, efficient ATP production equals enhanced toxic internal ROS formation. The synergistic combination of these two driving forces gave rise to the rapid evolution of eukaryotes.Also watch the Video Abstract. (shrink)

Traditional health sciences (including nursing) paradigms, conceptual models, and theories have relied heavily upon notions of the ‘person’ or ‘patient’ that are deeply rooted in humanistic principles. Our intention here, as a collective academic assemblage, is to question taken‐for‐granted definitions and assumptions of the ‘person’ from a critical posthumanist perspective. To do so, the cinematic works of filmmaker David Cronenberg offer a radical perspective to revisit our understanding of the ‘person’ in nursing and beyond. Cronenberg's work explores bodily transformation and (...) mutation, with the body as a fragile and malleable vessel. Cronenberg's work allows us to interrogate the body in all its complexity, contingency, and hybridity and provides avenues of rupture within current understandings of ‘the person’. Reinventing the definition of what it means to be human, critical posthumanism offers opportunities to both critique humanist theories and build affirmative futurities. Also drawing on the work of Deleuze and Guattari, specifically, their concept of becoming, we propose a critical posthumanist alternative to the conceptualization of the person in the health sciences, that of the becoming‐mutant, so frequently explored in Cronenberg's films. Such a conceptualization permits the inclusion of various technological interventions of the contemporary subject: The postperson. This position offers the health science disciplines a radical reconceptualization of the conceptual and theoretical approaches, extending beyond those trapped within the quagmire of humanistic principles. (shrink)

I argue that the phenomenal properties of conscious visual experiences are properties of the mind-independent objects to which the subject is perceptually related, mediated by the subject's practical understanding of their sensorimotor relation to those properties. This position conjoins two existing strategies for explaining the phenomenal character of perceptual experiences: accounts appealing to perceivers’ limited, non-inferential access to the details of their sensory relation to the environment, and the relationalist conception of phenomenal properties. Bringing these two positions together by emphasizing (...) their sensorimotor common ground allows each one to respond to damaging objections using the resources of the other. The resulting ‘sensorimotor relationalism’ about conscious vision provides a promising schema for explaining phenomenal properties of perceptual states, replacing ‘Hard’ questions with tractable ones about the perceptual relation and its sensorimotor underpinnings. (shrink)

What kind of symbiosis between archaeon and bacterium gave rise to their eventual merger at the origin of the eukaryotes? I hypothesize that conditions favouring bacterial uptake were based on exchange of intermediate carbohydrate metabolites required by recurring changes in availability and use of the two different terminal electron chain acceptors, the bacterial one being oxygen. Oxygen won, and definitive loss of the archaeal membrane potential allowed permanent establishment of the bacterial partner as the proto‐mitochondrion, further metabolic integration and highly (...) efficient ATP production. This represents initial symbiogenesis, when crucial eukaryotic traits arose in response to the archaeon‐bacterium merger. The attendant generation of internal reactive oxygen species (ROS) gave rise to a myriad of further eukaryotic adaptations, such as extreme mitochondrial genome reduction, nuclei, peroxisomes and meiotic sex. Eukaryotic origins could have started with shuffling intermediate metabolites as is still essential today. (shrink)

How do questions concerning consciousness and phenomenal experience relate to, or interface with, questions concerning plans, knowledge and intentions? At least in the case of visual experience the relation, we shall argue, is tight. Visual perceptual experience, we shall argue, is fixed by an agent’s direct unmediated knowledge concerning her poise (or apparent poise) over a currently enabled action space. An action space, in this specific sense, is to be understood not as a fine-grained matrix of possibilities for bodily movement, (...) but as a matrix of possibilities for pursuing and accomplishing one’s intentional actions, goals and projects. If this is correct, the links between planning, intention and perceptual experience are tight, while (contrary to some recent accounts invoking the notion of ‘sensorimotor expectations’) the links between embodied activity and perceptual experience, though real, are indirect. What matters is not bodily activity itself, but our practical knowledge (which need not be verbalized or in any way explicit) of our own possibilities for action. Such knowledge, selected, shaped and filtered by the grid of plans, goals, and intentions, plays, we argue, a constitutive role in explaining the content and character of visual perceptual experience. (shrink)

As free‐living organisms, alpha‐proteobacteria produce reactive oxygen species (ROS) that diffuse into the surroundings; once constrained inside the archaeal ancestor of eukaryotes, however, ROS production presented evolutionary pressures – especially because the alpha‐proteobacterial symbiont made more ROS, from a variety of substrates. I previously proposed that ratios of electrons coming from FADH2 and NADH (F/N ratios) correlate with ROS production levels during respiration, glucose breakdown having a much lower F/N ratio than longer fatty acid (FA) breakdown. Evidently, higher endogenous ROS (...) formation did not hinder eukaryotic evolution, so how were its disadvantages mitigated? I propose that the resulting selection pressures favoured the evolution of a variety of eukaryotic ‘innovations’: peroxisomes for FA breakdown, carnitine shuttles, the linkage of beta‐oxidation to antioxidant properties, uncoupling proteins (UCPs) and using mitochondrial uncoupling during beta‐oxidation to reduce ROS. Recently observed relationships between peroxisomes and mitochondria further support the model. (shrink)

Based on our respective research programs (psychiatry, forensic psychiatry, public health, HIV/AIDS, harm reduction) this article aims to use purposely non‐conventional means to present the substantial contribution of poststructuralist perspectives to knowledge development in nursing science in general and in our current research in particular. More specifically, we call on the work of Michel Foucault and Deleuze & Guattari to politicize nursing science using examples from our empirical research programs with marginal and often highly marginalized populations. We discuss the concepts (...) of power, discourse, and resistance to illustrate the essential contribution of poststructuralism to marginal, even “nomadic”, nursing research. (shrink)

Recently, a review regarding the mechanics and evolution of mitochondrial fission appeared in Nature. Surprisingly, it stated authoritatively that the mitochondrial outer membrane, in contrast with the inner membrane of bacterial descent, was acquired from the host, presumably during uptake. However, it has been known for quite some time that this membrane was also derived from the Gram‐negative, alpha‐proteobacterium related precursor of present‐day mitochondria. The zombie idea of the host membrane still surrounding the endosymbiont is not only wrong, but more (...) importantly, might hamper the proper conception of possible scenarios of eukaryogenesis. Why? Because it steers the imagination not only with regard to possible uptake mechanisms, but also regarding what went on before. Here I critically discuss both the evidence for the continuity of the bacterial outer membrane, the reasons for the persistence of the erroneous host membrane hypothesis and the wider implications of these misconceptions for the ideas regarding events occurring during the first steps towards the evolution of the eukaryotes and later major eukaryotic differentiations. I will also highlight some of the latest insights regarding different instances of endosymbiont evolution. (shrink)

Aspects of peroxisome evolution, uncoupling, carnitine shuttles, supercomplex formation, and missing neuronal fatty acid oxidation (FAO) are linked to reactive oxygen species (ROS) formation in respiratory chains. Oxidation of substrates with high FADH2/NADH (F/N) ratios (e.g., FAs) initiate ROS formation in Complex I due to insufficient availability of its electron acceptor (Q) and reverse electron transport from QH2, e.g., during FAO or glycerol‐3‐phosphate shuttle use. Here it is proposed that the Q‐cycle of Complex III contributes to enhanced ROS formation going (...) from low F/N ratio substrates (glucose) to high F/N substrates. This contribution is twofold: 1) Complex III uses Q as substrate, thus also competing with Complex I; 2) Complex III itself will produce more ROS under these conditions. I link this scenario to the universally observed Complex III dimerization. The Q‐cycle of Complex III thus again illustrates the tension between efficient ATP generation and endogenous ROS formation. This model can explain recent findings concerning succinate and ROS‐induced uncoupling. (shrink)

This article describes aspects of our biological nature that have contributed to the dangerous current state of societal, ecological and climatological affairs. Next, it deals with stratagems to take these aspects into account, so as to allow us better choices. I will concentrate on the concepts of evolved group mechanisms and “neoteny” and explain why they direct our responses throughout our lives. The connection between our biological make‐up and our vulnerability to the current rise of certain kinds of irrational, undemocratic, (...) populism is also laid bare. I will end by listing some simple, but possibly controversial, proposals that might have value in combating these societal tendencies and help decision making in a reality‐based, more scientific, manner. (shrink)