Connecting influence and leadership, the professor of business ethics assumes a sacred moral vocation. Directed towards the student's role in the marketplace, the business ethics course enjoins consideration of the values of social responsibility for the human community in its political, economic, and familial manifestations.

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 125 oped the theory of the swerve and applied it to the problem of voluntary action, also made use of it in his defense of moral responsibility" (l ~9-3o). The distinction Englert has in mind is between to hekousion and to eph' heroin, a distinction he had emphasized in his long chapter 5 on Aristotle, and insisted was important to Epicurus as well. But the promise is (...) not realized; we are told only that to eph' heroin is saved just as is to hekousion, by insisting that the swerve marks a causal break (135). The book then ends with some undigested matters: David Sedley's work on Epicurus 's On Nature and Don Fowler's suggestion that the mind's act of focus (epibole)might constitute a swerve. There is more to be said for their views. And more against. The last word on the subject has yet to be written. JEFFREY S. PURINTON Princeton University Gerard O'Daly. Augustine's Phzlosophy of Mind. Berkeley and Los Angeles: University of California Press, 1987. Pp. xii + 241. $35.00. Paul Rigby. Original Sin in Augustine's "Confessions." Ottawa: University of Ottawa Press, 1987. Pp. 137. Paper, $17.95. Augustine's philosophy of the human person is one of the most neuralgic points in his thought, and the neuralgic soreness spreads to almost every other compartment of his thinking. Since there is still much to learn in this troubled area, one can only welcome the publication of these two studies. O'Daly's book aspires to deal with the entire list of questions involved in the ancient world's Platonic tractatus De anima, whereas Rigby focuses on a single issue, critically evaluating (and largely refuting) the contention put forth by Athanase Sage in two classic articles: that the Augustine who wrote the Confessions had not yet come to think of humanity as guilty of original sin. The breadth of O'Daly's focus also betrays a distinctly confident attitude toward the wide array of matters he must discuss; he seems to view the Augustinian field as relatively trouble free. The central chapters of his book originated as a Habilitation thesis for the University of Heidelberg: hence the generous display of German scholarship, but also a greater serenity toward the difficulties non-German students might perhaps raise against some of his conclusions. He moves from Augustine's general theory of the soul, through claapters on the soul's "lower" activities (sense-perception, imagination, and memory), to that peculiar Augustinian preoccupation with the soul's measurement of time; he then concludes with the psychology of what Augustine would term "knowledge" in the higher (i.e., intellectual) sense of the term. The atmosphere throughout is encyclopedic, but then so is the impressive scale of O'Daly's learning; at the end, though, the reader is especially grateful for the two valuable indices---one topical the other an Index locorum--which help in retrieving the multitude both of texts and topics O'Daly handles. O'Daly is confident that Augustine's views on most of these matters solidified early on, so he feels entitled tojump about from early to late works and back again. Those who 126 JOURNAL OF THE HISTORY OF PHILOSOPHY 28:1 JANUARY 199o find Augustine's thought more fluid will question this methodology, even find it circular ; it supposes a continuity of thought which ought rather to be proven. But this nondevelopmental approach results in another loss--the living sense of context, the controlled excitement that invariably marks Augustine's own thinking, has mostly drained off. This is all the more disappointing since O'Daly writes a pleasing prose style. But that judgment may only reflect the preferential conviction that we still have more exciting things to learn about Augustine's philosophy of human nature than O'Daly is willing to admit. Is this, one wonders, the reason why he ignores the many relevant insights contained in Oliver DuRoy's massive study? He is particularly adamant on the question of the soul's origin, yet one is at liberty to doubt that forty-four years of Augustine's thinking on this gnawing issue can be treated adequately in a... (shrink)

This Element is a philosophical history of Social Darwinism. It begins by discussing the meaning of the term, moving then to its origins, paying particular attention to whether it is Charles Darwin or Herbert Spencer who is the true father of the idea. It gives an exposition of early thinking on the subject, covering Darwin and Spencer themselves and then on to Social Darwinism as found in American thought, with special emphasis on Andrew Carnegie, and Germany with special emphasis on (...) Friedrich von Bernhardi. Attention is also paid to outliers, notably the Englishman Alfred Russel Wallace, the Russian Peter Kropotkin, and the German Friedrich Nietzsche. From here we move into the twentieth century looking at Adolf Hitler - hardly a regular Social Darwinian given he did not believe in evolution - and in the Anglophone world, Julian Huxley and Edward O. Wilson, who reflected the concerns of their society. (shrink)

If we can wrong a work of art, then it has moral status. This paper considers two examples of putative wrongings of works of art, but in both cases, the claim that the work of art itself is wronged cannot be vindicated. The sense that a work of art has been wronged arises when that work has a special meaning for us or has a special standing in a cultural context. There is nothing intrinsic to works of art that can (...) confer moral status upon them, and so they are not moral patients. (shrink)

When Dr. van Fleteren writes of the articles I criticized as dating from some twenty years ago, the unwary reader might infer that my criticism of those articles was, for its part, relatively recent. The fact is, however, that when the two connected articles I eventually criticized appeared in the volumes of Augustinian Studies, I wrote this reply while Fr. Robert Russell, of happy memory, was still at the helm, and was promised publication in the near future. Meanwhile, however, Fr. (...) Russell had the discourtesy to move on to a more intimate acquaintance with Augustine than any of us on this confused planet can boast of, and someone sowed cockle into field he had tended: in unaccountable fashion my article seems to have disappeared. Only a recent letter of inquiry on my part, and Fr. Allan Fitzgerald’s understanding reply, resulted in this renewal of dialogue between Dr. van Fleteren and me. Let me assure both Dr. van Fleteren and Fr. Fitzgerald that I am grateful for giving it exactly that form, a courteous dialogue. (shrink)

The evidence for the effectiveness of rehabilitation of three types of attention—selectivity, sustained attention, and attentional switching—is reviewed. Limited but significant effects in all three domains are observed, though evidence for generalization to wider everyday life functions remains relatively sparse. In the case of sustained attention and also in the case of spatial selectivity, the modulating effects of arousal are shown to be important, and higher level executive deficits may at times be exacerbated or even caused by lowered levels of (...) arousal. Conversely, methods of modulating arousal may be used to improve sustained attention and executive functions in a range of clinical conditions. Attentional functions are key to other cognitive domains such as attention and perception, and so the promising evidence for attentional rehabilitation may contribute to the rehabilitation of other cognitive domains also. (shrink)

In this editorial, we argue that midwives should focus on climate change, a link which has been underexplored.

A globe-spanning investigation into the Transhumanist movement, considering the tech billionaires, scientific luminaries, and DIY body-hackers attempting to prolong, improve, and ultimately transcend the limits of human life.

This case note discusses the case of Baczkowski v. Poland in the European Court of Human Rights. The Court ruled that, where an elected mayor makes comments disapproving of homosexuality, and officials subsequently ban a Gay Pride march, then courts may be able to infer that the ban was discriminatory under Article 14 ECHR.

Assuming that the reader accepts, albeit provisionally, that James's "will" to believe, early and late, implies that his ethics is traversed by a deontological streak, and by a "faith" which implies epistemic form on the relevant facts (both interpretations the writer argued for in two previous essays), a final feature of his position entitles one to interpret his "will" to believe as, not merely a willingness or readiness, but as a controlling resolve, in the strong sense, to interpret the facts (...) in a manner appropriate to our living in the "strenuous mood," a mood which is congruent to our universe viewed as "moral." Consider, as a crucial instance, the will to believe which undergirds the "keeping" of a friendship. (shrink)

Narrowing the focus of his Soundings in St. Augustine's Imagination (1994) O'Connell (philosophy, Fordham U.) analyzes three decisive conversions portrayed in the Confessions: the youthful reading of Cicero, that sparked by the platonist books, and the final capitulation in the Milanese garden. He also compares the conversion imagery with that in the Dialogues of Cassicciacum to shed light on the question of two Augustines. Annotation copyrighted by Book News, Inc., Portland, OR.

Peirce’s doctrine of God has scarcely been studied at all. This is surprising because his own naturally religious temperament, his desire for philosophical completeness and the influence of Kant, all led him to give an important place to theistic speculation in his philosophy. It is true that few parts of his philosophy reveal more than the fragmentary and unfinished nature of his thinking. This however does not take away from its importance both for the interpretation of his philosophy and for (...) the evaluation of its contribution. In this paper I want to examine his doctrine of God mainly in order to discover and outline what views he held in the matter. Such examination is an essential preliminary to any consideration of the value of his theistic thinking. Moreover, an objective exposition is already the best beginning of evaluation. However it is impossible to undertake this kind of examination without a careful search into various corners of his writings and a meticulous and slightly laboured presentation of one’s findings. But I think that the patience involved in such research has a rich reward. (shrink)

William James' lecture on "The Will to Believe" has kindled spirited controversy. In this reappraisal of that controversy, Father O'Connell contributes some : that James' argument should be viewed against his indebtedness to Pascal and Renouvier; that it works primarily to validate our "over-beliefs" ; and most surprising perhaps, that James envisages our "passional nature" as intervening, not after, but before and throughout, our intellectual weighing of the evidence for belief. --From publisher's description.