Background: A growing number of frameworks for the practice of clinical ethics are described in the literature. Among these, hermeneutical frameworks have helped highlight the interpretive and contextual nature of clinical ethics practice. Objectives: The aim of this article is to further advance this body of work by drawing on the ideas of Charles Taylor, a leading hermeneutical philosopher. Design/Findings: A Hermeneutical Rapprochement Framework is presented for clinical ethics practice, based on Taylor’s hermeneutical “retrieval” and “rapprochement.” This builds on existing (...) hermeneutical approaches for the practice of clinical ethics by articulating a framework with interpretive and reconciliatory scope that extends beyond the presenting “local” context. A Hermeneutical Rapprochement Framework considers broader socio-historical horizons and imaginaries grounded on Taylor’s expansive work in epistemological, ontological, political, and moral philosophy. Discussion: The framework is discussed in terms of how it can be operationalized for clinical practice as well as normative development. Implications for the educational preparation of clinical ethicists are also discussed. Although this work is directly relevant for clinical ethicists, it can also help inform the ethical practice of all clinicians. (shrink)

This analysis presents an epistemological and moral examination of suffering. It addresses the specific questions: (1) What is suffering? (2) Can one's suffering be assessed by another? and (3) What is the moral significance of suffering? The epistemological analysis is orientated by Peter Hacker's framework for the investigation of emotions, demonstrating that suffering is an emotion. This leads to a discussion of whether suffering is a phenomenon that can be evaluated objectively by another person who is not experiencing the suffering, (...) questioning the validity of some decisional models for limiting life-sustaining therapies with the aim of preventing suffering. This analysis highlights that understandings of suffering are value laden. It is conventionally implied that suffering is `bad' and that it should be eliminated. Suffering is commonly regarded as a moral wrong that needs to be made right by health care. This article concludes with a recommendation for a paradigm shift in how suffering can be better understood, through the practice of empathic attunement. (shrink)

Hermeneutics, also referred to as interpretive phenomenology, has led to important contributions to nursing research. The philosophy of Charles Taylor has been a major source in the development of contemporary hermeneutics, through his ontological and epistemological articulations of the human sciences. The aim of this paper is to demonstrate that Taylor's ideas can further enrich hermeneutic inquiry in nursing research, particularly for investigations of ethical concerns. The paper begins with an outline of Taylor's hermeneutical framework, followed by a review of (...) his key ideas relevant for ethics research. The paper ends with a discussion of my empirical research with critically ill children in Canada and France in relation to Taylor's ideas, chiefly Social Imaginaries. I argue that Taylor's hermeneutics provides a substantive moral framework as well as a methodology for examining ethical concerns. (shrink)

Attention and adaptation are both mechanisms that optimize visual performance. Attention optimizes performance by increasing contrast sensitivity for and neural response to attended stimuli while decreasing them for unattended stimuli; adaptation optimizes performance by increasing contrast sensitivity for and neural response to changing stimuli while decreasing them for unchanging stimuli. We investigated whether and how the adaptation state and the attentional effect on contrast sensitivity interact. We measured contrast sensitivity with an orientation-discrimination task, in two adaptation conditions—adapt to 0% or (...) 100% contrast—in focused, distributed, and withdrawn attentional conditions. We used threshold and asymptotic performance to index the magnitude of the attentional effect—enhancement or impairment in contrast sensitivity—before and after adapting to high-contrast stimuli. The results show that attention and adaptation affect the contrast psychometric function in a similar but opposite way: Attention increases stimulus salience, whereas adaptation reduces stimulus salience. An interesting finding is that the adaptation state does not modulate the magnitude of the attentional effect. This suggests that attention affects the normalized signal once the effect of contrast adaptation has taken place and that these two mechanisms act separately to change contrast sensitivity. Attention can overcome adaptation to restore contrast sensitivity. (shrink)

We characterize the sets of all Π2 and all equation image theorems of IΠ−1 in terms of restricted exponentiation, and use these characterizations to prove that both sets are not deductively equivalent. We also discuss how these results generalize to n > 0. As an application, we prove that a conservation theorem of Beklemishev stating that IΠ−n + 1 is conservative over IΣ−n with respect to equation image sentences cannot be extended to Πn + 2 sentences. © 2011 WILEY-VCH Verlag (...) GmbH & Co. KGaA, Weinheim. (shrink)

Climate change's impact on investor behavior is a scantly investigated area in finance. This paper examines the performance of socially responsible exchange trade funds (ETFs) concerning conventional ETFs, in response to climate change events. We proxy climate change signals with a list of natural disaster events that NASA scientists relate to climate change. We contribute to existing literature, by using a very extensive information set of ETF strategies, not influenced by rating agencies' subjective evaluation policies, and covering almost 90% of (...) the universe of worldwide sustainability thematic-oriented ETFs. This sample allows us to identify the socially responsible investment behavior in response to unpredictable climate change shocks. Our identification strategy accounts for endogeneity concerns and relies on two-stage least square (2SLS) approach finding that responsible investors react to climate change events by purchasing socially responsible investments. The relationship between climate change signals and return of investment in themes linked to the development of sustainability is positive. Interestingly enough, the sign of this relationship is different, when we disentangle the empirical results according to the asset type, confirming that investors shift their investments from equity funds to bond funds when market sentiment worsens. Our results indicate that policymakers should increase the support of firms adopting environmentally conscious business practices, while managers should boost a sustainable business strategy. (shrink)

The majority of G protein-coupled receptors (GPCRs) self-assemble in the form dimeric/oligomeric complexes along the plasma membrane. Due to the molecular interactions they participate, GPCRs can potentially provide the framework for discriminating a wide variety of intercellular signals, as based on some kind of combinatorial receptor codes. GPCRs can in fact transduce signals from the external milieu by modifying the activity of such intracellular proteins as adenylyl cyclases, phospholipases and ion channels via interactions with specific G-proteins. However, in spite of (...) the number of cell functions they can actually control, both GPCRs and their associated signal transduction pathways are extremely well conserved, for only a few alleles with null or minor functional alterations have so far been found. This would seem to suggest that, beside a mechanism for DNA repairing, there must be another level of quality control that may help maintaining GPCRs rather stable throughout evolution. We propose here receptor oligomerization to be a basic molecular mechanism controlling GPCRs redundancy in many different cell types, and the plasma membrane as the first hierarchical cell structure at which selective categorical sensing may occur. Categorical sensing can be seen as the cellular capacity for identifying and ordering complex patterns of mixed signals out of a contextual matrix, i.e., the recognition of meaningful patterns out of ubiquitous signals. In this context, redundancy and degeneracy may appear as the required feature to integrate the cell system into functional units of progressively higher hierarchical levels. (shrink)

In this detailed study of the republican tradition in the development of the Enlightenment, the central problem of utopia and reform is crystallized in a discussion of the right to punish. Describing the political situation in Europe in the seventeenth and eighteenth centuries, the author shows how the old republics in Italy, Poland and Holland stagnated and were unable to survive in the age of absolutism. The Philosophes discussed the ideal of republicanism against this background. They were particularly influenced by (...) the political and religious radicalism of John Toland, which had survived the English Restoration and was then reaching Europe. Professor Venturi traces the debate on the penal laws and the attempt to relate utopian ideas of society to the practical problem of dealing with man in society, which culminated in the assertion by many Philosophes that an unjust social system necessitated harsh penal laws, thereby rejecting the possibility of reform. (shrink)

By a theorem of R. Kaye, J. Paris and C. Dimitracopoulos, the class of the Πn+1-sentences true in the standard model is the only consistent Πn+1-theory which extends the scheme of induction for parameter free Πn+1-formulas. Motivated by this result, we present a systematic study of extensions of bounded quantifier complexity of fragments of first-order Peano Arithmetic. Here, we improve that result and show that this property describes a general phenomenon valid for parameter free schemes. As a consequence, we obtain (...) results on the quantifier complexity, finite axiomatizability and relative strength of schemes for Δn+1-formulas. (shrink)

Any living organism interacts with and responds specifically to environmental molecules by expressing specific olfactory receptors. In this paper, this specificity will be first examined in causal terms with particular emphasis on the mechanisms controlling olfactory gene expression, cell-to-cell interactions and odor-decoding processes. However, this type of explanation does not entirely justify the role olfactory receptors have played during evolution, since they are also expressed ectopically in different organs and/or tissues. Homologous olfactory genes have in fact been found in such (...) diverse cells and/or organs as spermatozoa, testis and kidney where they are assumed to act as chemotactic sensors or renin modulators. To justify their functional diversity, homologous olfactory receptors are assumed to share the same basic role: that of conferring a self-identity to cells or tissues under varying environmental conditions. By adopting this standpoint, the functional attribution as olfactory or chemotactic sensors to these receptors should not be seen either as a cause conditioning receptor gene expression, or as a final effect resulting from genetically predetermined programs, but as a direct consequence of the environmental conditions olfactory receptor genes have explored during evolution. The association of odorant patterns with specific environmental or contextual situations makes their relationship semiotically triadic, due to the emergence of an interpretant capable of perceiving odorants as meaningful signs out of a noisy background. This perspective highlights the importance of odorant-receptor relationships as respect to the properties of the interacting partners. It is our contention that only when taken together can these different explanatory strategies provide a realistic account of how olfactory receptor genes have been structurally and functionally modified during evolution. (shrink)

Accepted standards of parental decisional autonomy and child best interests do not address adequately the complex moral problems involved in the care of critically ill children. A growing body of moral discourse is calling for the recognition of `tragedy' in selected human problems. A tragic dilemma is an irresolvable dilemma with forced terrible alternatives, where even the virtuous agent inescapably emerges with `dirty hands'. The shift in moral framework described here recognizes that the form of conduct called for by tragic (...) dilemmas is the practice of phronesis. The phronetic agent has acquired a capacity to discern good agency in tragic circumstances. This discernment is practiced through the artful creation of moral narratives: stories that convey that which is morally meaningful in a particular situation; that is, stories that are `meaning making'. The phronetic agent addresses tragic dilemmas involving children as a narrator of contextualized temporal embodied human (counter)stories. (shrink)

The author publishes the initial fragment of an unknown treatise by Leon Battista Alberti on the casting of statues written around 1455 and preserved in cod. Ottob. lat. 1870. The fragment contains a discussion on the nature of light and the element of fire.

Let T be a second-order arithmetical theory, Λ a well-order, λ < Λ and X ⊆ ℕ. We use $[\lambda |X]_T^{\rm{\Lambda }}\varphi$ as a formalization of “φ is provable from T and an oracle for the set X, using ω-rules of nesting depth at most λ”.For a set of formulas Γ, define predicative oracle reflection for T over Γ ) to be the schema that asserts that, if X ⊆ ℕ, Λ is a well-order and φ ∈ Γ, then$$\forall \,\lambda (...) < {\rm{\Lambda }}\,.$$In particular, define predicative oracle consistency ) as Pred–O–RFN{0=1}.Our main result is as follows. Let ATR0 be the second-order theory of Arithmetical Transfinite Recursion, ${\rm{RCA}}_0^{\rm{*}}$ be Weakened Recursive Comprehension and ACA be Arithmetical Comprehension with Full Induction. Then,$${\rm{ATR}}_0 \equiv {\rm{RCA}}_0^{\rm{*}} + {\rm{Pred - O - Cons\ }}\left \equiv {\rm{RCA}}_0^{\rm{*}} + \,{\rm{Pred - O - Cons\ }}\left \equiv {\rm{RCA}}_0^{\rm{*}} + \,{\rm{Pred - O - RFN}}\,_{{\bf{\Pi }}_2^1 } \left.$$We may even replace ${\rm{RCA}}_0^{\rm{*}}$ by the weaker ECA0, the second-order analogue of Elementary Arithmetic.Thus we characterize ATR0, a theory often considered to embody Predicative Reductionism, in terms of strong reflection and consistency principles. (shrink)

Concatenation, conjunction, and connection -- The sensitive infosphere -- Global skin : a trans-identitarian patchwork -- The aesthetic genealogy of globalization -- Language, limit, excess -- Avatars of the general intellect -- The swarm effect -- Social morphogenesis and neuroplasticity -- The transhuman -- The horizon of mutation -- Consciousness and evolution -- The end.

_ Source: _Volume 29, Issue 1, pp 86 - 102 The aim of this paper is to give an overview of the place that Hobbes assigns to optics in the context of his classification of sciences and disciplinary boundaries. To do this, I will begin with an account of Hobbes’s conception of philosophy or science, and particularly his distinction between true and hypothetical knowledge. I will also show that in his demarcation between mathematics or geometry and natural philosophy Hobbes was (...) influenced by Galileo’s _Dialogue_. I then analyse the consequences of this distinction for optics, and conclude by clarifying its status among the scientific disciplines. (shrink)

We show that the replacement rule of the sequent calculi ${\bf G3[mic]}^= $ in [8] can be replaced by the simpler rule in which one of the principal formulae is not repeated in the premiss.

This article casts light on the moral implications of the possibility of human extinction, with a specific focus on extinction caused by an interruption in human reproduction. In the first two paragraphs, I show that moral philosophy has not yet given promising explanations for the wrongness of this kind of extinction. Specifically, the second paragraph contains a detailed rejection of John Leslie’s main claims on the morality of extinction. In the third paragraph, I offer a demonstration of the fact that (...) a moral view which stresses the permissibility of some types of human extinction can be effectively constructed, while in the following paragraph I propose a prima facie defense of a new approach to the topic which is likely to provide us with reasons in favor of the wrongness of a premature departure of humankind. (shrink)

This paper investigates the status of the fragments of Peano Arithmetic obtained by restricting induction, collection and least number axiom schemes to formulas which are $${\Delta_1}$$ provably in an arithmetic theory T. In particular, we determine the provably total computable functions of this kind of theories. As an application, we obtain a reduction of the problem whether $${I\Delta_0 + \neg \mathit{exp}}$$ implies $${B\Sigma_1}$$ to a purely recursion-theoretic question.

This paper concerns late 1920 s attempts to construct unitary theories of gravity and electromagnetism. A first attempt using a non-standard connection—with torsion and zero-curvature—was carried out by Albert Einstein in a number of publications that appeared between 1928 and 1931. In 1929, Tullio Levi-Civita discussed Einstein’s geometric structure and deduced a new system of differential equations in a Riemannian manifold endowed with what is nowadays known as Levi-Civita connection. He attained an important result: Maxwell’s electromagnetic equations and the gravitational (...) equations were obtained exactly, while Einstein had deduced them only as a first order approximation. A main feature of Levi-Civita’s theory is the essential use of the Ricci’s rotation coefficients, introduced by Gregorio Ricci Curbastro many years before. We trace the history of Ricci’s coefficients that are still used today, and highlight their geometric and mechanical meaning. (shrink)

A recent trend in bioethics has highlighted the decisive role that solidarity plays in global health. However, given the impact and extent of the effects of climate change, which reach beyond present generations, it is important to consider whether this concept can be applied intergenerationally. Does it make sense to talk about solidarity with future generations? The objective of this article is to explore ‘amplified solidarity’, a new concept of solidarity that explains our obligations towards the health and quality of (...) life of future generations. The analysis of this concept is structured as follows: I first establish the moral relevance of future people and then investigate the traits of amplified solidarity, its challenges, and its relationship with other key principles. I propose that amplified solidarity needs both a critical imagination to be projected towards the future and an institutional framework to correct health injustices across an intergenerational timescale. Solidarity forms a potent triangular constellation with responsibility and justice to fight against global and intergenerational injustices. (shrink)

The aim of this article is to highlight the under-recognized merits of clinical ethics committees (CECs), to help ensure that the development of roles for clinical ethics consultants do not unwittingly compromise the valuable contributions that CECs can continue to provide. I argue that CECs can offer distinctive contributions to the clinical ethics consultation process that can complement and enrich the input provided by a clinical ethics consultant. These distinctions and complementarities should be further examined and developed. This will help (...) to optimize the synergistic contributions that CECs and clinical ethics consultants can make to promote the ethical treatment of patients and their families. (shrink)

The world population aged significantly over the twentieth century, leading to an increase in the number of individuals presenting progressive, incapacitating, incurable chronic-degenerative diseases. Advances in medicine to prolong life prompted the establishment of instruments to ensure their self-determination, namely the living will, which allows for an informed person to refuse a type of treatment considered unacceptable according to their set of values. From the knowledge on the progression of Alzheimer disease, it is possible to plan the medical care, even (...) though there is still no treatment available. Irreversible cognitive incapacity underlines the unrelenting loss of autonomy of the demented individual. Such a loss requires the provision of specific and permanent care. Major ethical issues are at stake in the physician–patient–family relationship, even when dementia is still at an early stage. The authors suggest that for an adequate health care planning in Alzheimer disease the living will can be presented to the patient in the early days of their geriatric care, as soon as the clinical, metabolic or even genetic diagnosis is accomplished. They also suggest that the appointment of a health care proxy should be done when the person is still in full enjoyment of his cognitive ability, and that the existence and scope of advance directives should be conveyed to any patient in the early stages of the disease. It follows that ethical guidelines should exist so that neurologists as well as other physicians that deal with these patients should discuss these issues as soon as possible after a diagnosis is reached. (shrink)

By a result of L.D. Beklemishev, the hierarchy of nested applications of the $$\Sigma _1$$ -collection rule over any $$\Pi _2$$ -axiomatizable base theory extending Elementary Arithmetic collapses to its first level. We prove that this result cannot in general be extended to base theories of arbitrary quantifier complexity. In fact, given any recursively enumerable set of true $$\Pi _2$$ -sentences, S, we construct a sound $$(\Sigma _2 \! \vee \! \Pi _2)$$ -axiomatized theory T extending S such that the (...) hierarchy of nested applications of the $$\Sigma _1$$ -collection rule over T is proper. Our construction uses some results on subrecursive degree theory obtained by L. Kristiansen. (shrink)

La primera parte del artículo presenta un raro texto titulado "Avertissements aux Confesseurs", que se completa con otros dos fragmentos y las "Ordenances synodales" para los confesores. Se muestra como ejemplo de los efectos prácticos del Concilio de Trento en la diócesis de Ginebra, como había hecho San Carlos Borromeo en Milán. La segunda parte del artículo se refiere a los penitentes, y aunque se basa principalmente en "Introducción a la vida devota" y "Conversaciones espirituales", también tiene en cuenta algunos (...) extractos de sus cartas, traducidas ahora por primera vez al español, así como algunos de sus sermones. La tercera parte trata de tres de los capítulos del "Tratado del amor de Dios", en el que San Francisco de Sales presenta su hermosa doctrina de la contrición, rechazada por la Reforma, pero confirmada por el Concilio de Trento. (shrink)

In this paper we continue the study of the theories IΔ n+1 (T), initiated in [7]. We focus on the quantifier complexity of these fragments and theirs (non)finite axiomatization. A characterization is obtained for the class of theories such that IΔ n+1 (T) is Π n+2 –axiomatizable. In particular, IΔ n+1 (IΔ n+1 ) gives an axiomatization of Th Π n+2 (IΔ n+1 ) and is not finitely axiomatizable. This fact relates the fragment IΔ n+1 (IΔ n+1 ) to induction (...) rule for Δ n+1 –formulas. Our arguments, involving a construction due to R. Kaye (see [9]), provide proofs of Parsons’ conservativeness theorem (see [16]) and (a weak version) of a result of L.D. Beklemishev on unnested applications of induction rules for Π n+2 and Δ n+1 formulas (see [2]). (shrink)

Cet article est consacré à la théorie des causes de Plutarque dans ses rapports avec le platonisme des premiers siècles de l’époque impériale. Le texte le plus important se trouve dans les chapitres 47-48 du dialogue De defectu oraculorum, où Plutarque présente une théorie dualiste des causes, qui admet deux genres de cause : d’une part la cause divine et rationnelle, qui comprend la cause finale et la cause efficiente, d’autre part la cause nécessaire et matérielle, qui comprend la matière (...) et la cause instrumentale. Cette version de la théorie des causes dépend, de manière directe ou indirecte, du Timée de Platon. Dans d’autres ouvrages, comme le De animae procreatione, Plutarque ajoute deux causes différentes, à savoir la cause paradigmatique, qui s’identifie avec le monde des idées ou avec dieu lui-même, et la cause du mouvement, représentée par l’âme pré-cosmique irrationnelle. Il est intéressant de remarquer que, dans son exposition de la théorie des causes, Plutarque emploie la description prépositionnelle, très répandue dans les écoles philosophiques : l’agent est donc to hyph’hou, le paradigme to pros ho, la matière to ex hou, alors que la cause finale est indiquée avec la formule to dia ho. (shrink)

This article discusses changes in post-apartheid South Africa’s economy and society in relation to the country’s re-insertion in the Empire. South Africa ’s specificity in the African context is largely related to the crucial role played in this case by the factory proletariat in defining the collapse of apartheid. Therefore, neoliberalism and the entry in the Empire in this case have to be understood in terms of state responses to a class composition that starting from workplace organisation has expressed a (...) resistance to the imposition of wage labour discipline. While the government of the African National Congress has successfully recodified its nationalist discourse to suit the requirements of capitalist globalisation and liberalization, this process has also been very contradictory. The adoption of a neoliberal agenda has, in particular, emphasized the ANC’s abdication from state sovereignty as a vehicle of strategies of control based on social citizenship. New movements, largely made of multitudes left out of waged employment, have therefore emerged to challenge the ANC’s pro-Empire choice. However, these movements are not based on a « souverainniste » agenda, or on delegation to the state of resistance to the Empire. Rather, in their conscious departure from nationalist and wage-based mythologies, they clarify the biopolitical nature of current processes of contestation and are able to combine grassroots struggles with cognitive abilities of reappropriation. (shrink)