“ The Origins of Genome Architecture ” by Michael Lynch (2007) may not immediately sound like a book that someone interested in the philosophy of biology would grab off the shelf. But there are three important reasons why you should read this book. Firstly, if you want to understand biological evolution, you should have at least a passing familiarity with evolutionary change at the level of the genome. This is not to say that everyone interested in evolution should be a (...) geneticist or a bioinformatician, but that a working knowledge of genetic change is an essential part of the intellectual toolkit of modern evolutionary biology, even if your primary focus is the evolution of behaviour or the diversity of communities. Secondly, this book provides excellent examples of another important tool in the biologist’s intellectual toolkit, but one that is rarely explained or illustrated to such an extent: null (or neutral) models. The role null models play in testing hypotheses in evolution is a central focus of this book. Thirdly, as an accomplished work of advocacy for a strictly microevolutionary view of evolution, this book provides grist for the mill for the important debate about whether population genetic processes are the sine qua non of evolutionary explanations. (shrink)

Does biology have general laws that apply to all levels of biological organisation, across all evolutionary time? In their book “Biology’s first law: the tendency for diversity and complexity to increase in evolutionary systems” (2010), Daniel McShea and Robert Brandon propose that the most fundamental law of biology is that all levels of biological organisation have an underlying tendency to become more complex and diverse over time. A range of processes, most notably selection, can prevent the expression of this tendency, (...) but they predict that, on average, we should see that lineages tend toward greater diversity and complexity, driven by fundamentally neutral processes. Their hypothesis can be summarised as “diversity is easy, stasis is hard”. Here, I consider evidence for this “zero force evolutionary law”. It provides a fair description of evolutionary change at the genomic level, but the predictions of the proposed law are not met for broad scale patterns in the evolution of the animal kingdom. (shrink)

One of the major benefits of interdisciplinary research is the chance to swap tools between fields, to save having to reinvent the wheel. The fields of language evolution and evolutionary biology have been swapping tools for centuries to the enrichment of both. Here I will discuss three categories of tool swapping: conceptual tools, where analogies are drawn between hypotheses, patterns or processes, so that one field can take advantage of the path cut through the intellectual jungle by the other; theoretical (...) tools, where the machinery developed to process the data in one field is adapted to be applied to the data of the other; and analytical tools, where common problems encountered in both fields can be solved using useful tricks developed by one or the other. I will argue that conceptual tools borrowed from linguistics contributed to the Darwinian revolution in biology; that theoretical tools of evolutionary change can in some cases be applied to both genetic and linguistic data without having to assume the underlying evolutionary processes are exactly the same; and that there are practical problems that have long been recognised in historical linguistics that may be solved by borrowing some useful analytical tools from evolutionary biology. (shrink)

The extended reliance on media can be seen as one indicator of mediatization. But even though we can assume that the pervasive character of digital media essentially changes the way people experience everyday life, we cannot take these experiences for granted. There has recently been a formulation of three tasks for mediatization research; historicity, specificity and measurability, needed to empirically verify mediatization processes across time and space. In this article, we present a tool designed to handle these tasks, by measuring (...) the extent to which people experience that media reach into the deeper layers of daily human life. The tool was tested in an empirical study conducted in Sweden in 2017. The results show that perceived media reliance is played out in relation to three types of basic desires: (1) (re)productive desires, (2) recognition desires, and (3) civic desires, and is socially structured and structuring. We argue this tool, in diachronic analyses, can measure one important aspect of mediatization. (shrink)

The word “gene” means different things to different people, and can even be used in multiple ways by the same individual. In this review, I follow a particular thread running through Griffith and Stotz’s “Genetics and Philosophy: an introduction”, which is the way that methods of investigation influence the way we define the concept of “gene”, from nineteen century breeding experiments to twenty-first century big data bioinformatics. These different views lead to a set of gene concepts, which only partially overlap (...) each other, each of which picks up on a different part of gene behaviour, function or scientific utility. This plurality of concepts carries over to the use of the concept of “information” in biology, where the non-overlapping concepts can be connected to whether you view the genome as a blueprint for development, a response to environmental triggers, an engine of heritability, or a document of history. (shrink)

This chapter is concerned with the Cambrian explosion. It considers only one particular kind of explanation for the Cambrian radiation: that major innovations in animal body plan were produced from relatively few genetic changes of large phenotypic effect. It investigates the developmental genetic hypothesis of the origin and maintenance of body plans. This chapter suggests that the genetic architecture underlying body plans was not set during the Cambrian and has been immutable since. It shows that the link between body plan (...) and phylum can become blurry when the minor phyla are considered. (shrink)

Phylogenies are increasingly being used to investigate human history, diversification and cultural evolution. While using phylogenies in this way is not new, new modes of analysis are being applied to inferring history, reconstructing past states, and examining processes of change. Phylogenies have the advantage of providing a way of creating a continuous history of all current populations, and they make a large number of analyses and hypothesis tests possible even when other forms of historical information are patchy or nonexistent. In (...) common with approaches taken in other historical sciences, phylogenetics is a way of reconstructing past and processes using the traces left in the present day. Trees, based on DNA, language, cultural traits, or other evidence, are now sprouting all over the academic landscape. The increasing use of phylogenetic analysis to understand human cultural evolution has been embraced by some, and scorned by others. The purpose of this article is not to review methods and applications of phylogenetic analyses, nor to consider the growing field of cultural phylogenetics, but, more broadly, to explore how we interpret phylogenies as narratives about human diversification. The first half of the article deals with meaning: phylogenies are often interpreted as histories, but a bifurcating tree is at best an abstract representation of history, and its connections to past events and processes is dependent on the data used, the assumptions made in the analysis, and the degree to which nodes in the tree (where one lineage splits into two) can be connected to change and movement in real populations. The second half of the article explores the purpose of phylogenies: a tree does not have to be a literal history of human lineages in order to be useful for investigating processes of human diversification. Phylogenies should not be read as accurate records of history, but as a way of exploring plausible explanations for current patterns of diversity. Phylogenies provide important information that can be used to test ideas about human diversity, and can help to guard against errors of inference arising from statistical artifacts. (shrink)

Overall assessments and balancing of interests -- Multi-criteria analysis -- Intuition -- Legal examples of decision-making with SAW -- Decision-making under uncertainty -- Evidentiary aspects.

Two core motivational systems have been conceptualized as underlying emotion and behavior. The approach system drives the organism toward stimuli or events in the environment, and the avoidance system instead deters the organism away from these stimuli or events. This approach—avoidance dichotomy has been central to theories of emotion. Advances in neuroscience complementing well-designed behavioral experiments have begun to elucidate the neural mechanisms underlying approach—avoidance motivation, suggesting that these two systems exist in parallel and are lateralized in the brain. This (...) review explores the notion of approach—avoidance and the cerebral lateralization of these motivational tendencies. (shrink)

Rutherford and Lindell (2011) review the theoretical and empirical research conceptualizing emotion and emotional processing within an approach-avoidance framework. This is accompanied by an extensive discussion of the cerebral lateralization of approach-avoidance. Berntson, Norman, and Cacioppo (2011) extend this discussion by presenting a bivariate evaluative model of emotion which adopts a valence-based (positive, negative) dictum. Here we discuss this latter model in the context of an approach-avoidance perspective.

This note investigates the class of finite initial segments of the cumulative hierarchy of pure sets. We show that this class is first-order definable over the class of finite directed graphs and that this class admits a first-order definable global linear order. We apply this last result to show that FO = FO.

Words like you, here, and tomorrow are different from other expressions in two ways. First, and by definition, they have different kinds of meanings, which are context-dependent in ways that the meanings of names and descriptions are not. Second, their meanings play a different kind of role in the interpretations of the utterances that contain them. For example, the meaning of you can be paraphrased by a description like "the addressee of the utterance." But an utterance of (1) doesn't say (...) the same thing as an utterance of (2). (shrink)

This Article examines the ways in which market vendors in Kampala, Uganda, responded to plans to redevelop their markets through the concession of long-term leases to private investors. These plans met with massive resistance from the marketers, with significant outcomes. The Article uncovers how the marketers actively negotiated a “gray space” between legality and illegality and creatively used the law, with a view to asserting themselves as the legitimate rulers of their markets. It shows how the marketers engaged in highly (...) diverse modalities of struggle, stretching across the legal/illegal boundary. They organized in multiple configurations which were flexible, hybrid and mutant in character, rather than being fixed in particular organizational categories. In their struggles, the marketers engaged in shifting alliances and with a disparate range of political allies. Their politics were fluid, untamed and pragmatic, but also contradictory and fractured. This flexibility and pragmatism enabled them to navigate a complex political landscape and to make instrumental use of a generally unfavorable legal environment. (shrink)

The aim of the study was to describe and compare whether women who used the pill or condoms discussed the choice of contraceptive method with their partner, and their sexual activity and interaction with their partner. It also studied women's thoughts about the attitudes of their partner and close others concerning unplanned pregnancy and abortion. A total of 134 women, aged 23-29, who had a stable partner relationship, answered three questionnaires. The contraceptive pill was used by 94 of the women (...) and 40 used condoms. The results show that most women discussed and planned choice and use of contraceptive method with their partner. However, more women whose partner used the condom discussed and talked about the use of the contraceptive method than women who used the pill. Independent of the contraceptive method, the women stated that non-agreement with the partner about the method resulted in no intercourse. More women who used the pill reported that they sometimes forgot to use it compared to women who used the condom. This latter group also stated to a higher degree that unplanned pregnancy would result in positive attitudes on the part of their partner and close others. (shrink)

A visual imagery task is presented which is beyond the limits of normal human ability, and some of the factors contributing to its difficulty are isolated by comparing the difficulty of related tasks. It is argued that complex objects are assigned hierarchical structural descriptions by being parsed into parts, each of which has its own local system of significant directions. Two quite different schemas for a wire‐frame cube are used to illustrate this theory, and some striking perceptual differences to which (...) they give rise are described. The difficulty of certain mental imagery tasks is shown to depend on which of the alternative structural descriptions of an object is used, and this is interpreted as evidence that structural descriptions are an important component of mental images. Finally, it is argued that analog transformations like mental folding involve changing the values of continuous variables in a structural description. (shrink)

This groundbreaking book revisits the writings of classic theorists in an effort re-evaluate the importance and influence the psychology of esteem has on the economy. The authors explore ways the economy of esteem may be reshaped to improve overall social outcomes and offer new ways of thinking about how society works and may be made to work.

This work makes available to readers without specialized training in mathematics complete proofs of the fundamental metatheorems of standard (i.e., basically ...

A history of the pre-Socratic philosophers, with selected writings and texts.

Background: Growing evidence suggests that collaborative practice improves healthcare outcomes, but the precursors to collaborative behavior between nurses and physicians have not been fully explored. Research question: The purpose of this descriptive correlational study was to describe the professional values held by nurses and their attitudes toward physician–nurse collaboration and to explore the relationships between nurses’ characteristics (e.g. education, type of work) and professional values and their attitudes toward nurse–physician collaboration. Research design: This descriptive correlational study examines the relationship between (...) nurses’ professional values (Nurses Professional Values Scale–Revised) and their attitudes toward nurse–physician collaboration (Jefferson Scale of Attitudes toward Physician–Nurse Collaboration). Ethical considerations: Permission to conduct the study was received from the hospital, and the Institutional Review Boards of the healthcare system and the participating university. Participants/context: A convenience sample of 231 registered nurses from a tertiary hospital in the United States was surveyed. Findings: A significant positive relationship was found between nurses’ professional values and better attitudes toward collaboration with physicians ( r =.26, p <.01). Attitude toward collaboration with physicians was also positively associated with master’s or higher levels of education ( F(3, 224) = 4.379, p =.005). Discussion: The results of this study can be helpful to nurse administrators who are responsible for developing highly collaborative healthcare teams and for nurse educators who are focused on developing professional values in future nurses. (shrink)

The present work is a systematic study of five frameworks or perspectives articulating mathematical structuralism, whose core idea is that mathematics is concerned primarily with interrelations in abstraction from the nature of objects. The first two, set-theoretic and category-theoretic, arose within mathematics itself. After exposing a number of problems, the book considers three further perspectives formulated by logicians and philosophers of mathematics: sui generis, treating structures as abstract universals, modal, eliminating structures as objects in favor of freely entertained logical possibilities, (...) and finally, modal-set-theoretic, a sort of synthesis of the set-theoretic and modal perspectives. (shrink)

The principle of sufficient reason threatens modal collapse. Some have suggested that by appealing to the indefinite extensibility of contingent truth, the threat is neutralized. This paper argues that this is not so. If the indefinite extensibility of contingent truth is developed in an analogous fashion to the most promising models of the indefinite extensibility of the concept set, plausible principles permit the derivation of modal collapse.

This paper explores the relationship between attitudes to corporate social responsibility (CSR) and the cultural dimensions of business activity identified by Hofstede & Hofstede using a sample of nearly 90,000 stakeholders drawn from 28 countries. We develop five general propositions relating attitudes to CSR to aspects of culture. We show that the propensity of consumers to punish firms for bad behaviour varies in ways that appear to relate closely to the cultural characteristics identified by Hofstede. Furthermore, this variation appears to (...) be understandable in terms of the standard interpretation of the Hofstede dimensions, suggesting that cultural variation in the attitudes of consumers may play an important role in helping us to understand variations in CSR across countries. This in turn has implications for how managers of multinational companies should implement CSR strategies in different cultural contexts. (shrink)

With developments in the 19th and early 20th centuries, structuralist ideas concerning the subject matter of mathematics have become commonplace. Yet fundamental questions concerning structures and relations themselves as well as the scope of structuralist analyses remain to be answered. The distinction between axioms as defining conditions and axioms as assertions is highlighted as is the problem of the indefinite extendability of any putatively all-embracing realm of structures. This chapter systematically compares four main versions: set-theoretic structuralism, a version taking structures (...) as sui generis universals, structuralism based on category theory, and a quasi-nominalist modal-structuralism. While none of the approaches is problem-free, it appears that some synthesis of the category-theoretic approach with modal-structuralism can meet the challenges set out, given the notion of “logical possibility.”. (shrink)

University of Virginia, USA, lel3f{at}virginia.edu ' + u + '@' + d + ' '//--> The strategy of this article is to consider republicanism in contrast with liberalism. We focus on three aspects of this contrast: republicanism’s emphasis on ‘social goods’ under various conceptualizations of that category; republicanism’s emphasis on political participation as an essential element of the ‘good life’; and republicanism’s distinctive understanding of freedom (following the lines developed by Pettit). In each case, we are skeptical that what republicanism (...) offers is superior to the liberal alternative and indicate the grounds for that skepticism. Key Words: republicanism • liberalism • social goods • political participation • republican freedom. (shrink)

Berkeley is one of the most influential and yet most misunderstood of eighteenth-century philosophers. In this new, revised edition of his classic introduction, G.J. Warnock examines all Berkeley's major philosophical works and discusses his most original and interesting contributions to questions still debated by philosophers today. The aim of the book is to help the reader learn not so much about Berkeley, but rather, through Berkeley, something about philosophy itself.

A plurality of approaches to foundational aspects of mathematics is a fact of life. Two loci of this are discussed here, the classicism/constructivism controversy over standards of proof, and the plurality of universes of discourse for mathematics arising in set theory and in category theory, whose problematic relationship is discussed. The first case illustrates the hypothesis that a sufficiently rich subject matter may require a multiplicity of approaches. The second case, while in some respects special to mathematics, raises issues of (...) ontological multiplicity and relativity encountered in the natural sciences as well. (shrink)

The value of rational choice theory for the social sciences has long been contested. It is argued here that, in the debate over its role, it is necessary to distinguish between claims that people maximise manifest payoffs, and claims that people maximise their utility. The former version has been falsified. The latter is unfalsifiable, because utility cannot be observed. In principle, utility maximisation can be adapted to fit any form of behaviour, including the behaviour of non-human organisms. Allegedly 'inconsistent' behaviour (...) is also impossible to establish without qualification. This utility-maximising version of rational choice theory has the character of a universal 'explanation' that can be made to 'fit' any set of events. This is a sign of weakness rather than strength. In its excessive quest for generality, utility-maximising rational choice theory fails to focus on the historically and geographically specific features of socio-economic systems. As long as such theory is confined to ahistorical generalities, then it will remain highly limited in dealing with the real world. Instead we have to consider the real social and psychological determinants of human behaviour. (shrink)

1. Is consciousness vague? This paper will argue that it is. But, first, we need to get clear on the meaning of the question.I will take vagueness to consist in the possibility of borderline cases....

I argue that the effectiveness of forgiveness in the healing of relationships is dependent on both the givers and recipients of forgiveness understanding that once it has been granted, forgiveness is not normally able to be retracted. When we forgive, we make a firm commitment not to return to our former state of moral resentment against the offender, replacing it by good-will. This commitment can be broken only where the forgiving party makes some significant cognitive adjustment to her appraisal of (...) either the offender or the offence, believing that her original forgiveness was granted in error. I reject the view that forgiveness can lapse or be withdrawn on the basis of a return of hurt or disappointed feelings, arguing that these do not amount to a restoration of the resentment that is extinguished when forgiveness is granted. I contend that a person who ‘forgives’ and later takes back that ‘forgiveness’ because certain negative feelings have returned either did not genuinely forgive in the first place or shows that she has not fully grasped the nature of forgiveness. (shrink)

This paper considers on what basis justice may require that people be treated as equals. It begins with an examination of the argument that people are to be treated as equals because they are equals, and suggests reasons for thinking that such an argument is unlikely to succeed. The remainder of the paper considers, and tries to make plausible, the argument that justice requires people be treated as equals because they are individuals. Thus the paper offers some support for the (...) view that the proper foundation of egalitarianism is individualism. (shrink)