Compensation for research related injuries is a subject that is increasingly gaining traction in developing countries which are burgeoning destinations of multi center research. However, the existence of disparate compensation rules violates the ethical principle of fairness. The current paper presents a comparison of the policies of Brazil, Russia, India, China and South Africa. A systematic search of good clinical practice guidelines was conducted employing search strategies modeled in line with the recommendations of ADPTE Collaboration. The search focused on three (...) main areas namely bibliographic data bases, clinical practice guidelines data bases and a restricted internet search. A manual search of references cited in relevant guideline documents was also conducted. The search terms, Medical Subject Headings and key words were developed for a PubMed platform and then adapted for all other data bases. The search terms were kept constant for each country with the only difference being the country name. The documents so obtained were subjected to systematic content analysis. The study revealed that there is vast panoply of regulations which exist on a continuum. On one extreme is India with comprehensive regulations that are codified into law, and on the other end there is China which does not have specific laws regulating research related injuries. There are a number of differences and similarities such as mandatory insurance requirements, existence of no fault compensation, compensable injuries and the role of research ethics committees. It is imperative to enact legislations that protect participants without stifling the research enterprise. There is need for consistency and ideally harmonization of such regulations at a global level. A model policy on compensation for research related injuries should borrow from the best aspects of the different country policies and should be informed by the cardinal ethics principles of autonomy, justice and beneficence. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:F/Actual Knowing:Putting Facts and Values in PlaceHolmes Rolston III (bio)Knowing needs to be actualized, an act of ours, yet also a discovery of what is actually, factually there. In place ourselves, we manage some awareness of other places. Agents in our knowing, we co-respond, and this emplaces us. But we humans have powers of dis-placement too, of taking up, whether empathetically or objectively, the situations of others, other (...) humans, sometimes others than humans. How do our facts depend on our acts? Do we humans always put in place, or sometimes find put, placed there before us, what we variously value on Earth?To put this provocatively: We need to "green" our beliefs; but every educated person knows that nothing out there is really "green." "Seeing green" is an interaction experience. Perhaps this perceptual experience is a model for the whole: all of our human concepts and percepts color up the world. This is true alike of facts and of values, discoveries and evaluations. Such knowing might be well enough placed, but it is always and only "placed." Our geographical position controls our epistemic composition. Epistemology is inevitably anthropocentric; we are always located in the center of our knowing.But what if the "green" we see is mostly chlorophyll? Photosynthesis is not something we can see at all. In place on Earth, we humans breathe oxygen and would die in minutes without it; we depend on photosynthesis at the foundation of our food chains. We know our own respiratory [End Page 137] and trophic interactions with the plants, and this not simply at the native range experiences of breathing and eating. We have figured out the oxygen/carbon-dioxide/water cycles taking place at molecular levels.Now it seems, however, that we are discovering ourselves placed where the facts are bigger than our acts, including our respiratory (and perceptual) interactions; these extend systemically and are hardly anthropocentric. Epistemologically, we have more to evaluate. "Greening" our belief, environmentally grounding it, will require knowing and appropriately respecting these vital life processes—of which we are a part, but which also are "in place" and "take place" apart from us.1. Embodied, Knowledgeable PersonsWhatever knowledge we gain has to "come through" at our native range. That seems uncontroversial, but what are the implications? Knowledge is relative to our location, our embodiment, our size, our terrestrial habitat. This situation constricts, it may be claimed, what can "come through." Mark Johnson concludes: "Our consciousness and rationality are tied to our bodily orientations and interactions in and with our environment. Our embodiment is essential to who we are, to what meaning is, and to our ability to draw rational inferences and to be creative." He urges us to "put the body back into the mind," that is, epistemologically, to become aware of how the body is there, willy-nilly (1987, xxxviii, xxxvi). Joining with George Lakoff, he claims: "Reason, even in its most abstract form, makes use of, rather than transcends, our animal nature" (Lakoff and Johnson 1999, 4).Katherine Hayles continues: "To be incorporated within a different body would be to live in a different world." She features "interactivity" and explains:Interactivity foregrounds rather than obscures the importance of embodiment. In the interaction model, the body does more than provide a biological support system for the mind. Interaction is possible only because we are embodied, and the precise conditions of our embodiment have everything to do with the nature of those interactions. The range and nature of sensory stimuli available to us, the contexts that affect how those sensory stimuli achieve meaning, the habituated movements and postures that we learn through culture and that are encoded for gender, ethnicity, and class—all affect how learning takes place and how the world comes into being for us.(1995, 56) [End Page 138]All this seems true, if one means that with reincarnation our native range experiences would be different. Wolves have keen noses and with them they experience, if you like, a different world. But the survival value of wolf noses, a situated knowledge for them, is equally true for humans, wolves, and elk, because all three... (shrink)

Drawing on a historical ethnography of how Brazil’s post-dictatorial psychiatric reforms have shaped young people’s lives, this paper builds on Eve Sedgwick’s analysis of the hermeneutics of suspicion to show that narrow applications of Foucault’s biopower concept nurture forms of resistance to bio-reductionism centred primarily on epistemic deconstruction. To unsettle this hermeneutic, I put young people’s theories of power into conversation with Georges Canguilhem’s concept of the milieu and with feminist scholars’ work on prefigurative politics. I introduce the concepts of (...) threading and unthreading to consider how one subject of biopower, the child-like biobehavioural figure, was continuously being threaded within a specific milieu and in relation to another key figure: the elite angst-ridden ‘storm-and-stress’ adolescent. Young people’s subsequent unthreading and reweaving politics, flourishing in co-construction with what I call the politicizing clinic, illustrate how decolonial pedagogies can incrementally change the patterning of social life. (shrink)

The long 19th century was a period of many developments and technical innovations in agriculture and animal biology, during which actors sought to incorporate new practices in light of new information. By the middle of the century, however, while heredity steadily became the dominant concept in animal husbandry, some policies related to livestock improvement in Brazil seemed to have been tailored following a climate-deterministic concept established in the mid-18th century by the French naturalist Georges-Louis Leclerc, the Comte de Buffon. His (...) theory of animal degeneration posited, among other things, the necessity of recurrent crossbreeding to preserve animal species living in nonnative environments from climate-induced degeneration. Although largely discredited by the early 19th century, the teachings of the French naturalist seem to have found supporters in a Brazilian program to modernize national agriculture through the application of the natural sciences. Herein I examine the revival of Buffon’s theories in that government-sponsored program to improve animal husbandry and breeding techniques, including actual applications of this theory in the real world. Ultimately, I argue that Buffon’s theory of degeneration was used to tailor public policies and funding for the improvement of domesticated animals in Brazil between 1856 and 1860. (shrink)

In this work I search for elements that contribute to the development of the ethical dimension of environmental education. I start with the existence of what C.A. Bowers calls “areas of silence” in the curriculum in both schools and universities. The reason for this silence, I argue, is to be found in the Cartesian conceptual structures of curricula. I suggest that the works of Bacon, Galileo and Descartes provoke a twofold process that I have termed the forgetting of tradition and (...) objectification of nature. As a corrective to this process, I explore the possibilities that the philosophical hermeneutics of Hans-Georg Gadamer opens for rehabilitation of tradition and de-objectification of nature. I work with the concept of the “dignity of things” present in Greek dialectics: that nature is not simply a projection of mind (as the neo-Kantians claim), but something that thought suffers. In my conclusions I argue that for nature to be reinserted into almost all areas of knowledge it is necessary that we respect “the otherness of nature.”. (shrink)

In this paper, I respond to what is currently the most significant criticism of the principle fair play as a basis for political obligations. In a series of cases in which obligations appear to be established by fair play, important scholars contend that the moral principle at work is not fair play but a natural duty of justice to provide essential benefits to other people. Such natural duty accounts strikingly ignore requirements of reciprocity, to make appropriate return for benefits received. (...) In addition, careful examination of possible natural duty explanations of such cases indicates severe difficulties explaining exactly to whom the natural duties in question are owed and why they may require significant costs. (shrink)

Psychedelic drugs such as psilocybin, LSD and DMT are known to induce powerful alterations in phenomenology. Perhaps of most philosophical and scientific interest is their capacity to disrupt and even “dissolve” one of the most primary features of normal experience: that of being a self. Such “peak” or “mystical” experiences are of increasing interest for their potentially transformative therapeutic value. While empirical research is underway, a theoretical conception of the mechanisms underpinning these experiences remains elusive. In the following paper, psychedelic-induced (...) ego-dissolution is accounted for within an active inference framework, as a collapse in the “temporal thickness” of an agent’s deep temporal model, as a result of lowered precision on high-level priors. The argument here is composed of three moves: first, a view of the self-model is proposed as arising within a temporally deep generative model of an embodied organism navigating an affordance landscape in the service of allostasis. Next, a view of the action of psychedelics as lowering the precision of high-level priors within the generative model is unpacked in terms of a high Bayesian learning rate. Finally, the relaxation of high-level priors is argued to cause a “collapse” in the temporal thickness of the generative model, resulting in a collapse in the self-model and a loss of the ordinary sense of being a self. This account has implications for our understanding of ordinary self-consciousness and disruptions in self-consciousness present in psychosis, autism, depression, and dissociative disorders. The philosophical, theoretical and therapeutic implications of this account are touched upon. (shrink)

This paper examines people's reasoning about identity continuity and its relation to previous research on how people value one-of-a-kind artifacts, such as artwork. We propose that judgments about the continuity of artworks are related to judgments about the continuity of individual persons because art objects are seen as physical extensions of their creators. We report a reanalysis of previous data and the results of two new empirical studies that test this hypothesis. The first study demonstrates that the mere categorization of (...) an object as “art” versus “a tool” changes people's intuitions about the persistence of those objects over time. In a second study, we examine some conditions that may lead artworks to be thought of as different from other artifacts. These observations inform both current understanding of what makes some objects one-of-a-kind as well as broader questions regarding how people intuitively think about the persistence of human agents. (shrink)

Many systems of logic diagrams have been offered both historically and more recently. Each of them has clear limitations. An original alternative system is offered here. It is simpler, more natural, and more expressively and inferentially powerful. It can be used to analyze not only syllogisms but arguments involving relational terms and unanalyzed statement terms.

It is widely thought to be unfair to hold people responsible, or to blame or punish them, for wrongful acts or omissions that are beyond their control. Because this principle is often taken to support incompatibilism, and because it has led many to deny the possibility of moral luck, we might expect its normative underpinnings to have been carefully scrutinized. However, surprisingly, they have not. In the current paper, I will try to fill this gap by first reconstructing, and then (...) criticizing, what I take to be the principle’s most compelling rationale. Because I will argue that that rationale is irretrievably flawed, the thrust of my discussion will be to raise doubts both about the principle itself and about the philosophical theses that it is said to support. (shrink)

It is widely held in theories of narrative that all works of literary narrative fiction include a narrator who fictionally tells the story. However, it is also granted that the personal qualities of a narrator may be more or less radically effaced. Recently, philosophers and film theorists have debated whether movies similarly involve implicit audio-visual narrators. Those who answer affirmatively allow that these cinematic narrators will be radically effaced. Their opponents deny that audio-visual narrators figure in the ontology of movies (...) at all, and many have argued that the ‘effaced’ literary narrator is an illusion as well. In this paper, I attempt to sort out the central issues that arise in these debates, defending the existence of effaced narrators in both literature and film. (shrink)

Each world faith tradition has its own distinctive relationship with science, and the science-religion dialogue benefits from a greater awareness of what this relationship is. In this book, members of the International Society for Science and Religion (ISSR) offer international and multi-faith perspectives on how new discoveries in science are met with insights regarding spiritual realities.The essays reflect the conviction that “religion and science each proceed best when they’re pursued in dialogue with each other, and also that our fragmented and (...) divided world would benefit more from a stronger dialogue between science and religion.” In Part One, George F. R. Ellis, John C. Polkinghorne, and Holmes Rolston III, each a Templeton Prize winner, discuss their views on why the science and religion dialogue matters. They are joined in Part Two by distinguished theologians Fraser Watts and Philip Clayton, who place the dialogue in an international context; John Polkinghorne’s inaugural address to the ISSR in 2002 is also included. In Part Three, five members of the ISSR look at the distinctive relationships of their faiths to science: •Carl Feit on Judaism •Munawar Anees on Islam •B.V. Subbarayappa on Hinduism •Trinh Xuan Thuan on Buddhism •Heup Young Kim on Asian Christianity George Ellis, the recently elected second president of ISSR, summarizes the contributions of his colleagues. Ronald Cole-Turner then concludes the book with a discussion of the future of the science and religion dialogue. (shrink)

For fifty years, Willard Van Orman Quine's books and articles have stimulated intense debate in the fields of logic and the philosophy of language. Many scholars in fact, regard Quine as the greatest living English-speaking philosopher; yet his views remain widely misunderstood and misinterpreted. This book provides the first major explication and defense of Quine's systematic philosophy and is ideally suited for use as a required or supplementary text in a wide variety of undergraduate and graduate courses in philosophy and (...) linguistics.The book explores the far-reaching implications of Quine's views on language for contemporary analytic philosophy. It is unique in providing a lucid and rich description and reconstruction of the historical context from which Quine's work grew, focusing in particular on the role that Russell and Wittgenstein played in shaping the problems inherited by Quine. It presents Quine's difficult later views in an accessible fashion, bringing out as no other study has the very radical nature of his position. One of the book's highlights is its careful examination and assessment of Tarski's theory of truth as it relates to the traditions of Russell and Wittgenstein and to Quine's own philosophy.George D. Romanos took his Ph.D. in philosophy under George D. W. Berry and Paul T. Sagal at Boston University. This book grew out of his dissertation with the active criticism and support of Quine himself. (shrink)

Philosophical (p-) zombies are constructs that possess all of the behavioral features and responses of a sentient human being, yet are not conscious. P-zombies are intimately linked to the hard problem of consciousness and have been invoked as arguments against physicalist approaches. But what if we were to invert the characteristics of p-zombies? Such an inverse (i-) zombie would possess all of the behavioral features and responses of an insensate being yet would nonetheless be conscious. While p-zombies are logically possible (...) but naturally improbable, an approximation of i-zombies actually exists: individuals experiencing what is referred to as “anesthesia awareness.” Patients under general anesthesia may be intubated (preventing speech), paralyzed (preventing movement), and narcotized (minimizing response to nociceptive stimuli). Thus, they appear—and typically are—unconscious. In 1-2 cases/1000, however, patients may be aware of intraoperative events, sometimes without any objective indices. Furthermore, a much higher percentage of patients (22% in a recent study) may have the subjective experience of dreaming during general anesthesia. P-zombies confront us with the hard problem of consciousness—how do we explain the presence of qualia? I-zombies present a more practical problem—how do we detect the presence of qualia? The current investigation compares p-zombies to i-zombies and explores the “hard problem” of unconsciousness with a focus on anesthesia awareness. (shrink)

RECENT PHILOSOPHICAL ATTENTION TO THE LANGUAGE OF DISEASE HAS FOCUSED PRIMARILY ON THE QUESTION OF ITS VALUE-NEUTRALITY OR NON-NEUTRALITY. PROPONENTS OF THE VALUE-NEUTRALITY THESIS SYMBOLICALLY COMBINE POLITICAL AND OTHER CRITICISMS OF MEDICINE IN AN ATTACK ON WHAT THEY SEE AS VALUE-INFECTED USES OF DISEASE LANGUAGE. THE PRESENT ESSAY ARGUES AGAINST TWO THESES ASSOCIATED WITH THIS VIEW: A METHODOLOGICAL THESIS WHICH TENDS TO DIVORCE THE ANALYSIS OF DISEASE LANGUAGE FROM THE CONTEXT OF THE PRACTICE OF MEDICINE AND A SUBSTANTIVE THESIS WHICH (...) HOLDS THAT DISEASE LANGUAGE IS EVALUATIVELY NEUTRAL. IN PARTICULAR, THE ESSAY CRITICALLY FOCUSES ON THE VALUE NEUTRAL POSITION ADOPTED BY CHRISTOPHER BOORSE, WHICH HE TERMS A FUNCTIONAL THEORY OF DISEASE. THE ARGUMENT CONCERNS WHETHER OR NOT ONE CAN HAVE VALUE NEUTRAL DESCRIPTION OF DISEASE STATES OR WHETHER DISEASE LANGUAGE ESSENTIALLY INVOLVES VALUES. (shrink)

George Grant's magnificent four-part meditation sums up much that is central to his own thought, including a critique of modern liberalism, an analysis of John Rawls's Theory of Justice, and insights into the larger Western philosophical ...

In the Bible, the human God-relationship is typically established through and by the phenomenon of “calling”. However, for much subsequent theology, this has been displaced by “vision”, “taste” or “feeling”. Referring to the notion of an inner word, the paper follows Kierkegaard's treatment of silence as, alternatively, a mode of inattention and attention to such an inner word. With Heidegger, the paper turns to the notion of vocation, both as in the discussion of the call of conscience in Being and (...) Time and the poetic vocation exemplified in the figure and poetry of Hölderlin. Finally, it considers the possible difference between such a poetic vocation and a divine calling. (shrink)

Santayana argues that instinct and imagination are crucial to the emergence of reason from chaos. Santayana's Life of Reason, published in five books from 1905 to 1906, ranks as one of the greatest works in modern philosophical naturalism. Acknowledging the natural material bases of human life, Santayana traces the development of the human capacity for appreciating and cultivating the ideal. It is a capacity he exhibits as he articulates a continuity running through animal impulse, practical intelligence, and ideal harmony in (...) reason, society, art, religion, and science. The work is an exquisitely rendered vision of human life lived sanely. In this first book of the work, Santayana provides an account of how the human animal develops instinct, passion, and chaotic experience into rationality and ideal life. Inspired by Aristotle's De Anima, Darwin's evolutionary theory, and William James's The Principles of Psychology, Santayana contends that the requirements of action in a hazardous and uncertain environment are the sources of the development of mind. More specifically, instinct and imagination are crucial to the emergence of reason from chaos. Separating himself from the typical thought of the time by his recognition of the imagination, Santayana in this volume offers extensive critiques of various philosophies of mind, including those of Kant and the British empiricists. This Critical Edition, volume VII of The Works of George Santayana, includes a chronology, notes, bibliography, textual commentary, lists of variants, and other tools useful to Santayana scholars. The other four books of the volume include Reason in Society, Reason in Religion, Reason in Art, and Reason in Science. (shrink)

The British have often denied the very existence of a tradition of English literary theory. George Watson redeems that denial in his latest book, the first study of 20th Century English theory. The book begins with Yeats, Pound and Eliot, who made England their home. In subsequent chapters, based on personal recollection as well as published sources, it assesses the contribution of I.A. Richards, William Empson, F.R. Leavis, C.S. Lewis, Isaiah Berlin and Wittgenstein, as well as Marxists like E.P. (...) Thompson and Raymond Williams. English literary theory is a tradition that has suffered in reputation, paradoxically, by the sheer fertility of its invention. In this seminal work the author celebrates that fertility from the First World War downto the death of Iris Murdoch in 1999, showing that England pioneered the academic study of theories of literature years in advance of France or the USA. (shrink)

American healthcare -- Bioterror and bioart -- State of emergency -- Licensed to torture -- Hunger strikes -- War -- Cancer -- Drug dealing -- Toxic tinkering -- Abortion -- Culture of death -- Patient safety -- Global health -- Statue of security -- Pandemic fear -- Bioidentifiers -- Genetic genocide.

The article examines the polemic in the surangama sutra against the possibility of establishing any spacial relation between consciousness, the sense organs, and the external world. the arguments lead to the negative conclusion that consciousness cannot be said to have spacial location without contradicting experience. the article then takes this argument and applies it to the physiology of vision showing that visual perception cannot, in principle, be located neurologically.