The “impossibility” in our title is similar to what Emmanuel Falque designates by the notion of “outside phenomenon”, namely a region as excepting itself from the dialectic of logos and chaos. “Out of phenomenon” in the sense here of a principial impossibility of “saying oneself”, affecting in turn the “self” (saying oneself) and its expression (saying oneself). Phenomenology has taught us that there is no ego as below the cogito. No self‑foundation guarantees the reference that is marked in the (lexical) (...) expression: “self”. From this correlation between egoism and narrativity, we will retain in this article only the essential affirmation, namely that the self is above all a saying: an act of speech, not about itself, nor from itself, but as adhering to itself in such a way that no gap remains between the word (self) and the referent (self). The self becomes from then on like a performance (of language). Almost a reduction. But what happens when the self is affected by a radical aphasia? (shrink)

Cancers rely on multiple, heterogeneous processes at different scales, pertaining to many biomedical fields. Therefore, understanding cancer is necessarily an interdisciplinary task that requires placing specialised experimental and clinical research into a broader conceptual, theoretical, and methodological framework. Without such a framework, oncology will collect piecemeal results, with scant dialogue between the different scientific communities studying cancer. We argue that one important way forward in service of a more successful dialogue is through greater integration of applied sciences (experimental and clinical) (...) with conceptual and theoretical approaches, informed by philosophical methods. By way of illustration, we explore six central themes: (i) the role of mutations in cancer; (ii) the clonal evolution of cancer cells; (iii) the relationship between cancer and multicellularity; (iv) the tumour microenvironment; (v) the immune system; and (vi) stem cells. In each case, we examine open questions in the scientific literature through a philosophical methodology and show the benefit of such a synergy for the scientific and medical understanding of cancer. (shrink)

This book consists of Gregory Vlastos' studies on a variety of themes in Plato's metaphysics, epistemology, ethics, and social philosophy. Although many of the essays have appeared in various philosophical and classical journals or symposia, new in the volume are two major studies. One is on Plato's theory of love, exploring its metaphysical dimension and its far-reaching implications for personal and political relations. The other centers on semantic and logical problems in the Sophist; it offers solutions to crucial difficulties in (...) this fundamental Platonic work. In these essays the author presents ideas which are likely to provoke comment and may be discussed as vigorously in scholarly journals as has some of his earlier work. The other papers, some of them extensively revised, comprise virtually all the author's published work on Plato, with the exception of a few papers easily accessible elsewhere. This second edition includes three additional essays and extensive notes that were not included in the original edition. (shrink)

This is the companion volume to Gregory Vlastos' highly acclaimed work Socrates: Ironist and Moral Philosopher. Four ground-breaking papers which laid the basis for his understanding of Socrates are collected here, in revised form: they examine Socrates' elenctic method of investigative argument, his disavowal of knowledge, his concern for definition, and the complications of his relationship with the Athenian democracy. The fifth chapter is a new and provocative discussion of Socrates' arguments in the Protagoras and Laches. The epilogue 'Socrates and (...) Vietnam' suggests that Socrates was not, as Plato claimed, the most just man of his time. The papers have been prepared for publication by Professor Myles Burnyeat with the minimum of editorial intervention. (shrink)

Psychophysical scaling models of the form R = f, with R the response and I some intensity of an attribute, all assume that people judge the amounts of an attribute. With simple biases excepted, most also assume that judgments are independent of space, time, and features of the situation other than the one being judged. Many data support these ideas: Magnitude estimations of brightness increase with luminance. Nevertheless, I argue that the general model is wrong. The stabilized retinal image literature (...) shows that nothing is seen if light does not change over time. The classification literature shows that dimensions often combine to produce emergent properties that cannot be described by the elements in the stimulus. These and other effects cannot be adjusted for by simply adding variables to the general model because some factors do not combine linearly. The proposed alternative is that people initially judge the entire stimulus – the object in terms of its environment. This agrees with the constancy literature that shows that objects and their attributes are identified through their relations to other aspects of the scene. That the environment determines judgments is masked in scaling studies where the standard procedure is to hold context constant. In a typical brightness study the essential stimulus might be the intensity of the light or a difference between the light and the background. The two are perfectly confounded. This issue is examined in the case of audition. Judgments of the loudness of a tone depend on how much that tone differs from the previous tone in both pitch and loudness. To judge loudness people first seem to process the stimulus object in terms of differences between it and other aspects in the situation; only then do they assess the feature of interest. Psychophysical judgments will therefore be better interpreted by theories of attention that are based in biology or psychology than those that are based in classical physics. (shrink)

The use of contingent valuation methods for estimating the economic value of environmental improvements and damages has increased significantly. However, doubts exist regarding the validity of the usual willingness to pay CV methods. In this article, we examine the CV approach in light of recent findings from behavioral decision research regarding the constructive nature of human preferences. We argue that a principal source of problems with conventional CV methods is that they impose unrealistic cognitive demands upon respondents. We propose a (...) new CV approach, based on the value-structuring capabilities of multiattribute utility theory and decision analysis, and discuss its advantages and disadvantages. (shrink)

W. V. Quine was the most important naturalistic philosopher of the twentieth century and a major impetus for the recent resurgence of the view that empirical science is our best avenue to knowledge. His views, however, have not been well understood. Critics charge that Quine’s naturalized epistemology is circular and that it cannot be normative. Yet, such criticisms stem from a cluster of fundamental traditional assumptions regarding language, theory, and the knowing subject – the very presuppositions that Quine is at (...) pains to reject. Through investigation of Quine’s views regarding language, knowledge, and reality, the author offers a new interpretation of Quine’s naturalism. The naturalism/antinaturalism debate can be advanced only by acknowledging and critiquing the substantial theoretical commitments implicit in the traditional view. Gregory argues that the responses to the circularity and non-normativity objections do just that. His analysis further reveals that Quine’s departure from the tradition penetrates the conception of the knowing subject, and he thus offers a new and engaging defence of Quine’s naturalism. (shrink)

This book presents an original and creative enactment of a confrontation between Heidegger and Plato. Gregory Fried outlines a new approach to ethics and politics combining skeptical idealism and what he calls polemical ethics, and goes on to apply polemical ethics to the crucial questions around fascism and racism.

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Ideas 61.3 (2000) 433-452 [Access article in PDF] When Ideas Matter: The Moral Philosophy of Fontenelle Gregory Matthew Adkins Introduction There has been a recent trend in the historiography of seventeenth- and eighteenth-century intellectual culture to analyze that culture from a sociological perspective. This perspective, a necessary corrective to a pure history of ideas, takes knowledge as a socially constructed phenomenon and thus subject (...) to sociological analysis. The point of the sociology of knowledge, however, is not to re-hash and bolster old externalist arguments but to do away with the whole debate over whether ideas or social conditions are more important in intellectual history and the history of science. A focus on sociology does not mean that ideas do not matter. This becomes apparent when analyzing the ethics of early modern intellectuals.For example, Anne Goldgar's recent work, Impolite Learning: Conduct and Community in the Republic of Letters, 1680-1750 (1995), gives much attention to the sociology of the seventeenth- and eighteenth-century Republic of Letters--but at the cost of relegating the role of ideas to the sidelines. According to Goldgar, if one wants to understand early modern intellectuals as a community, including their ethics and sense of morality, one should focus on forms of sociability rather than the ideas and philosophies they put forth in their writings. An aristocratic ethic dominated early modern scholarship, she argues, and even took precedence over knowledge claims: "[i]n striving to make its inner workings acceptable to the outside community the Republic of Letters chose, like the aristocracy, to empty its internal relationships of content, choosing instead to concentrate on form.... [A]rguments were often judged on the politeness with which they were presented, rather than on their intrinsic merit." 1 Men of [End Page 433] letters, although often of humble origin, cultivated nobility by emulating aristocratic modes of decorum and noble interests in status and reputation. One way they promoted these ideas was through a literary genre adopted from classical antiquity, the éloge (eulogy), which presented exemplary modes of behavior by praising the lives of the "heroes" of the Republic of Letters. Interestingly, the years on which Goldgar focuses her analysis almost precisely encompass the period of Bernard le Bouyer de Fontenelle's mature intellectual production. Yet Fontenelle (1657-1757), widely hailed during his lifetime as having perfected the art of the éloge, plays no role in her argument.From 1699 to 1740 Fontenelle, as secrétaire perpétuel of the Académie Royale des Sciences, composed some sixty-nine éloges in honor of recently deceased members of the academy and of other notable savants. Even a brief glance at Fontenelle's eulogies reveals an intimate link between philosophy and morality. A more careful examination of them in the context of his life and works shows that this link was logically commensurate with his genuinely held notions of human nature, happiness, reason, and the good. In fact the relationship in the eulogies between notions of nobility and the virtues proper to the savant or philosopher is highly intellectualized. Fontenelle was not as concerned with status and reputation or with self-fashioning as one might think. 2 We can only assimilate his ethics to those of the court aristocracy if we ignore what he actually wrote.Through his eulogies and other writings, Fontenelle's thoughts on philosophy and morality have had a lasting impact on western culture. He presented an image of what would come to characterize the proper, objective, modern scientist and thinker. 3 In order to understand the éloge as an institution in the Republic of Letters (and by extension the early modern intellectual ethic) it is therefore important to examine Fontenelle's moral philosophy more carefully. It is a philosophy expressed in his eulogies but understood clearly only in the context of his life and works. On the ÉlogesAs noted above, one way to contextualize the institution of the éloge is to place it within a Republic of Letters concerned with adopting the manners of the nobility: the éloges... (shrink)

We use the path integral form of quantum electrodynamics to show that a causal classical limit to QED can be derived by functionally integrating over the photon coordinates, starting from an initial photon vacuum and ending in a final coherent radiation state driven by the anticipated classical charged particle trajectories. The resulting charged particle transition amplitude depends only on particle coordinates. When the \ limit is taken, only those particle paths that are not constrained by the final radiation state are (...) varied. These results demonstrate that the collapse from an infinity of charged particle paths, a path integral description, to causally interacting classical trajectories, a stationary-action description, is critically dependent on including final coherent state radiation and maintaining the distinction between particle paths that are free to vary and those trajectories that can be monitored by the final state radiation. (shrink)

Gregory Vlastos was one of the twentieth century's most influential scholars of ancient philosophy. Over a span of more than fifty years, he published essays and book reviews that established his place as a leading authority on early Greek philosophy. The two volumes that comprise Studies in Greek Philosophy include nearly forty contributions by this acknowledged master of the philosophical essay. Many of these pieces are now considered to be classics in the field. Perhaps more than any other modern scholar, (...) Gregory Vlastos was responsible for raising standards of research, analysis, and exposition in classical philosophy to new levels of excellence. His essays have served as paradigms of scholarship for several generations. Available for the first time in a comprehensive collection, these contributions reveal the author's ability to combine the skills of a philosopher, philologist, and historian of ideas in addressing some of the most difficult problems of ancient philosophy. Volume I collects Vlastos's essays on Presocratic philosophy. Wide-ranging concept studies link Greek science, religion, and politics with philosophy. Individual studies illuminate the thought of major philosophers such as Heraclitus, Parmenides, Anaxagoras, and Democritus. A magisterial series of studies on Zeno of Elea reveals the author's power in source criticism and logical analysis. Volume II contains essays on the thought of Socrates, Plato, and later thinkers and essays dealing with ethical, social, and political issues as well as metaphysics, science, and the foundations of mathematics. (shrink)

Among the most interesting of the controversies in the recent history of parapsychology and related studies is the claim made in 1933 by the psychical researcher Harry Price that the medium Rudi Schneider had on one particular occasion produced his psychic effects by fraudulent means. The background to this event, and the controversy which followed it, are described in detail in this article, which draws on many hitherto unpublished materials. The issues involved range from the design of experiments in an (...) unusual area of science, through the relation between fringe and orthodox science, to the role of popularisers of science and the ethics of science. (shrink)

While he develops three different aspects of Lacan's “Real,” Slavoj Žižek does so only partially, in the end leaving an inconsistent and contradictory account. Here these three versions of the Real are outlined and clarified by showing their relation to Marx's account of capitalist exchange and socialist politics. This leads to a discussion of two other aspects of the Real that appear in Žižek's work: the pre-Symbolic Real and the “Sinthome.” Where the former is simultaneously the fear of a unified (...) working class and the fantasy of a world of “total enjoyment” without conflict, the latter is discussed here in terms of political struggle that takes on not only the form of a means to an end but also that of an end in itself. (shrink)

Georg Northoff employs a comparison with Parkinson's disease in an effort to tease apart the underlying pathophysiology of psychogenic catatonia. Northoff's extensive treatment of the subject is abetted by his own research as well as the research of others. Nevertheless, a number of points concerning basal ganglia/thalamocortical processing need to be raised, some adding support to his hypothesis and others detracting from it.

In Considerations on Western Marxism, released in 1976, Perry Anderson stated and vindicated an affiliation to the Trotskyist tradition long apparent from the pages of New Left Review under his editorship. Central to this tradition, in its orthodox forms, was a historico-political perspective which regarded the Soviet Union as ‘degenerate’ or ‘deformed’ ‘workers’ states’ – post-capitalist social formations whose complex character dictated rejection of Stalinism and anti-Sovietism alike. In Anderson's case, this orientation received a Deutscherite inflection: abroad, no less than (...) at home, Soviet power was a contradictory phenomenon, by turns reactionary and progressive. The potential regeneration of the Russian Revolution and its sequels, whether via ‘proletarian revolution’ from below, or bureaucratic reformation from above, remained an article of faith among Marxists of this observance to the end. Accordingly, the debacle of Gorbachevite perestroika proved a profoundly disorientating experience for many who lent little or no credence to the mendacious claims of ‘actually existing socialism'. Amid capitalist euphoria at Communist collapse, what was to be said – and done? Anderson's displaced answer was forthcoming in 1992 in ‘The Ends of History’. (shrink)

This collection of essays examines urban communities and societies in Asia and the West to shed much-needed light on issues that have emerged as the world experiences its new urban turn. An urbanized world should be an improving place, one that is better to live in, one where humans can flourish. This book examines contemporary practices of care of the self in cities in Asia and the West, including challenges to citizenship and even the right to the city itself. Written (...) by a range of academics from different backgrounds (from architecture and urbanism, anthropology, social science, psychology, gender studies, history, and philosophy) their trans- and multidisciplinary approaches shed valuable light on what are sometimes quite old problems, leading to fresh perspectives and news ways of dealing with them. One thing that unites all of these papers is their people-centred approach, because, after all, a city is its people. (shrink)

Frege's Grundgesetze der Arithmetik offers a conception of cpLogic as the study of functions. Among functions are included those that are concepts, i.e. characteristic functions whose values are the logical objects that are the True/the False. What, in Frege's view, are the objects the True/the False? Frege's stroke functions are themselves concepts. His stipulation introducing his negation stroke mentions that it yields [...]. But curiously no accommodating axiom is given, and there is no such theorem. Why is it that some (...) of Frege's informal stipulations never made appearances as axioms? I offer an explanation that sheds new light on the Grundgesetze. No axioms should over-determination the True as a logical object. Perhaps the True = 0, as would be common in the mathematics of characteristic functions. But the logical objects that are cardinal numbers are value ranges correlated with second-level numerical concepts by a non-homogeneous second-level value-range function [...]. The existence of concepts would be ontologically circular if the True is itself a number. We find this circularity perfectly agreeable to Frege, and suggest that he had accepted that the existence of functions that are concepts in his cpLogic may well be ontologically inseparable from the existence of his value-range function. His cpLogic itself stands or falls with the viability of some value-range function. (shrink)

As noted In Part II of this series, perhaps the most critical elements to define in deciding when treatment Is futile are the goals of therapy from, both the physician's and the patient's point of view. A patient's personal goals are based upon value system., life goals, and personal definition of “quality of life.” These personal goals must then be interpreted and applied in a reasonable and realistic fashion against what the physician has previously described as the legitimate, objective, and (...) attainable therapeutic goals. As far as possible, both, parties must work together to eliminate the uncertainties in their discussion. The ideal situation includes a competent, alert patient and a prudent, caring physician who have had a long-term ongoing relationship. The key to collaboration is communication: a sincere interest in and professional concern for the patient; a willingness to be honest and open; a commitment to talk and to listen; an attempt to make one another feel comfortable in the collaboration; and an effort to recognize and to overcome barriers to communication, whether barriers are personal to either the patient or the physician or are professional, institutional, or societal. (shrink)