Delineation of the subthalamic nuclei on MRI is critical for deep brain stimulation surgery in patients with Parkinson’s disease. We propose this retrospective cohort study for quantitative analysis of MR signal-to-noise ratio, contrast, and signal difference-to-noise ratio of the STN on pre-operative three-dimensional stereotactic MRI in patients with medication-refractory PD. Forty-five consecutive patients with medication-refractory PD who underwent STN-DBS surgery in our hospital from January 2018 to June 2021 were included in this study. All patients had whole-brain 3D MRI, including (...) T2-weighted imaging, T2-weighted fluid-attenuated inversion recovery, and susceptibility-weighted imaging, at 3.0 T scanner for stereotactic navigation. The signal intensities of the STN, corona radiata, and background noise were obtained after placing regions of interest on corresponding structures. Quantitative comparisons of SNR, contrast, and SDNR of the STN between MR pulse sequences, including the T2WI, FLAIR, and SWI. Subgroup analysis regarding patients’ sex, age, and duration of treatment. We used one-way repeated measures analysis of variance for quantitative comparisons of SNR, contrast, and SDNR of the STN between different MR pulse sequences, and we also used the dependent t-test for the post hoc tests. In addition, we used Mann–Whitney U test for subgroup analyses. Both the contrast and SDNR were highest on FLAIR. The SNR was highest on SWI, and both the SNR and SDNR were lowest on T2WI. Subgroup analyses demonstrated significantly lower SDNR on SWI for patients receiving medication treatment for ≥13 years. In conclusion, on 3D stereotactic MRI of medication-refractory PD patients, the contrast and SDNR for the STN are highest on FLAIR, suggesting the optimal delineation of STN on FLAIR. (shrink)

At the individual level, the "selfish" and "moral" is the human nature of the two virtues, are not contradictory; in the type of structure the social level, in order to maintain order in the expansion of cooperation required to build and market society to adapt to the social moral foundation. China's traditional lack of a social and moral society in this dimension, Hume in a specific historical period's social and moral discourse for the construction of Chinese contemporary theory of market (...) economy with special reference. Universal code of ethics is the premise of economics, economics of their own value judgments guidelines also reject unethical economic behavior. "A market economy can be unscrupulous," the proposition is not established. On the perspective of individual, "Selfish" and "Moral" are both characteristics within human nature; On another perspective of society, in order to maintain the extending of cooperative order, it is important to construct the moral baserof the society which should be accordant with the market. However, Chinese traditional society is absences of the social moral. The theory of "social moral" which was raised by David Hume on particular moment plays an extremely important role in our current development of market economy. Universal moral rule is the precondition of economics theory. Furthermore, the valuation rule of economy theory also rejects the immoral economy behavior. So the proposition "market economy is immoral" cannot be tenable. (shrink)

Because they are key components of aircraft, improving the safety, reliability and economy of engines is crucial. To ensure flight safety and reduce the cost of maintenance during aircraft engine operation, a prognostics and health management system that focuses on fault diagnosis, health assessment, and life prediction is introduced to solve the problems. Predicting the remaining useful life is the most important information for making decisions about aircraft engine operation and maintenance, and it relies largely on the selection of performance (...) degradation features. The choice of such features is highly significant, but there are some weaknesses in the current algorithm for RUL prediction, notably, the inability to obtain tendencies from the data. Especially with aircraft engines, extracting useful degradation features from multisensor data with complex correlations is a key technical problem that has hindered the implementation of degradation assessment. To solve these problems, deep learning has been proposed in recent years to exploit multiple layers of nonlinear information processing for unsupervised self-learning of features. This paper presents a deep learning approach to predict the RUL of an aircraft engine based on a stacked sparse autoencoder and logistic regression. The stacked sparse autoencoder is used to automatically extract performance degradation features from multiple sensors on the aircraft engine and to fuse multiple features through multilayer self-learning. Logistic regression is used to predict the remaining useful life. However, the hyperparameters of the deep learning, which significantly impact the feature extraction and prediction performance, are determined based on expert experience in most cases. The grid search method is introduced in this paper to optimize the hyperparameters of the proposed aircraft engine RUL prediction model. An application of this method of predicting the RUL of an aircraft engine with a benchmark dataset is employed to demonstrate the effectiveness of the proposed approach. (shrink)

Brain arteriovenous malformations (bAVMs) are abnormal vessels that are prone to rupture, causing life-threatening intracranial bleeding. The mechanism of bAVM formation is poorly understood. Nevertheless, animal studies revealed that gene mutation in endothelial cells (ECs) and angiogenic stimulation are necessary for bAVM initiation. Evidence collected through analyzing bAVM specimens of human and mouse models indicate that cells other than ECs also are involved in bAVM pathogenesis. Both human and mouse bAVMs vessels showed lower mural cell-coverage, suggesting a role of pericytes (...) and vascular smooth muscle cells (vSMCs) in bAVM pathogenesis. Perivascular astrocytes also are important in maintaining cerebral vascular function and take part in bAVM development. Furthermore, higher inflammatory cytokines in bAVM tissue and blood demonstrate the contribution of inflammatory cells in bAVM progression, and rupture. The goal of this paper is to provide our current understanding of the roles of different cellular loci in bAVM pathogenesis. (shrink)

以严复的中西文化观为核心,将中国与西欧这两大思想文化体系,在历史的纵向发展与时代的横向座标这一大背景下,作宏观与微观的对比分析。.

This is a comparative study of the discourses on the nature of sacred language found in Indian Abhidharma texts and their counterparts by seventh century Chinese Buddhist scholars who, unlike the Indian Buddhists, questioned "the essence of the Buddha's teaching," and developed intellectual dialogues through their texts. ;In the Indian Abhidharma texts, Sa ngitiparyaya, Jnanaprasthana, Mahavibhasa, Abhidharmakosa, and Nyayanusara, the nature of the Buddha's word was either "sound," the oral component of speech, or "name," the component of language that conveys (...) meaning, or both. I show that the Sautrantikas refused to accept the category of "name," which was abstract and hypothetical to them. However, the attitude of the opposing Sarvastivadins, attested in the Mahavibhasa, for whom "name" was approved in their ontological structure, was ambivalent. In the Abhidharmakosa, both positions were introduced without commentary. Sanghabhadra, an ardent Sarvastivadin, was the only one who explicitly claimed that "name" should be the nature of the Buddha's word. ;What was mainly a linguistic debate in India became transformed in China into a religious and metaphysical one. Chiao-t'i, "the essence of the Buddha's word," was used for the first time by Hsuan-tsang for buddhavacana, "the word of the Buddha" in Sanskrit. Adding the term "essence" altered the nature of the debate. Wonch'uk was the first to view the issue from the broad perspective of its history and provenance in the Indian Buddhist texts. K'uei-chi incorporated it into Yogacara: the Buddha's teaching is what is represented in sentient beings' minds. Fa-tsang defined the essence of the Buddha's teaching as the truth appearing in the mind of the Buddha, which he equated with the truth of the Hua-yen world, tathata. This gradual but candid process of dialogue on "the Buddha's word" preluded a transition to "Chinese" Buddhism. An inquiry no longer in the category of language or of epistemological investigation claims its own identity in the Chinese discussion querying the "essence" or "substance" of the Buddha's teaching, and even "Buddhism" itself, transcending the distinction between language and meaning. (shrink)

本书共分两大部分:一为“关于‘启蒙’的再反思”,共由12篇文章组成;二是“世俗化与现代性”,由13篇文章组成。全书对西方启蒙运动及中国明清以来的启蒙思想脉络进行了一番梳理,有助于读者更加深入地了解启蒙 运动、世俗化与现代化的关系。.

90 nian dai, Du Weiming xian sheng de geng duo jing li zai yu kai zhan "wen hua Zhongguo" de lun yu."Wen hua Zhongguo" zhuo mo zui duo de shi ru jia de ren wen jing shen, yi jiu zheng jiang ru jia ru shi de jia zhi qu xiang he fan su ren wen zhu yi hun wei yi tan de yin xiang, tu xian ru jia yi mai xiang cheng de pi pan jing shen.

河北省哲学社会科学规划研究2002年度项目河北省教育厅2005年度著作出版基金资助.

Ben shu gong you ba jiang zu cheng, fen bie shi sheng ren bi ke xue er zhi, Wang Yangming de xin xue ti xi, shi gong yu bing xue, wen xue si xiang yu shi wen chuang zuo, jiao yu si xiang yu shi jian, Yangming hou xue, Yangming xue zai jin xian dai de ying xiang, Yangming wen hua yu Guizhou lü you. Mei ge lun ti lun shu ji zhong, shen du shi zhong, xu shu xing yu (...) yan tong su liu chang, gu shi xing qiang, hen shi he da zhong du zhe yue du. wei qi fa du zhe si kao, zeng qiang yue du xiao guo, zai mei yi jiang zhi hou shi liang she zhi le yi xie ming ci jie shi, jian da tao lun ti. ling pei he xiang guan wen zi, she zhi le yi xie tu pian, bei ke he Yangming shu fa zuo pin deng, ju you ji jia de guan shang xing. (shrink)

Ru jia jing shen dui yu xian dang dai de Zhongguo ren lai shuo ying xiang shi ju da de, ru jia jing shen yi shen tou dao Zhongguo ren de yi yan yi xing zhong, shi ji shang cheng wei Zhonghua min zu nei ju de jing shen niu dai. ben shu zuo zhe yi qing song, you mei de bi diao xiang guang da du zhe xi tong jie shao liao ru jia jing shen de ji ben nei (...) han, li shi yan bian. ben shu shi guang da du zhe xue xi Zhongguo chuan tong wen hua de tong su du wu. (shrink)

Este texto relaciona la filosofía de Byung-Chul Han, específicamente su concepto de cansancio, con la teoría de la intencionalidad de Edmund Husserl. Aun cuando estos dos desarrollos filosóficos son distantes cronológicamente y distintos epistemológicamente, se intenta verificar la posibilidad de una proximidad entre las dos argumentaciones filosóficas. El análisis se lleva a cabo a partir de los textos La sociedad del cansancio, de Han (2012), en el cual el autor trata del cansancio en la sociedad del inicio del siglo XXI; (...) Wahrnehmung und Aufmerksamkeit (Hua 38) (Beilage II, § 9) y Experiencia y juicio (§ 15-21 y 51), de Husserl (1980; 2004), que abordan aspectos afectivos/sensibles del sujeto en la percepción. El filósofo surcoreano se dedica a la crítica de la sociedad tardomoderna, mientras que el filósofo alemán, cuando expone posibles límites de la percepción, considera restricciones afectivas y la sensibilidad del yo. Para esta aproximación, se propone la hipótesis del cansancio de Han como un fenómeno semejante a los límites de la percepción analizados por Husserl. Para verificar la aproximación, se realizaron los siguientes pasos: análisis del concepto de cansancio en el pensamiento de Han; examen de los límites de la percepción, según Husserl; presentación de posibles aproximaciones entre esas dos perspectivas y, finalmente, exposición de las conclusiones. (shrink)

Ben shu yi "zhou xin shi dai" Zhongguo wen hua ren wen xing te zheng xing cheng ji qi dui Zhongguo zhe xue te zhi de su zao wei qie ru dian, zai xi tong shu li ru xue xin xing lun de ji ben zhu ti he li shi fa zhan, jie shi qi te zheng de ji chu shang, cong dao de yu sheng ming, dao de shi jian deng fang mian dui tang jun yi dao de xing (...) shang xue jin xing le shen ru de yan jiu. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Feminist Studies 47, no. 2. © 2021 by Feminist Studies, Inc. 251 7 preface 8 In recent years, people all over the world have become ever more aware of being drawn into intimate—and unequal—relations with one another, whether through environmental crises, the COVID-19 pandemic, global economic commodity chains, violent conflicts, forced displacements, or political protests and social movements. This special issue features China’s so-called rising presence as one of (...) the key nodes in these global intimacies. The essays by Mei-Hua Chen and Hong-zen Wang, Sealing Cheng, and Wei Wei contribute new approaches to migrant intimacies across borders through their ethnographically rich analyses. Chen and Wang explore cross-border marriages and sex work between Taiwanese men and Mainland Chinese and southeast Asian women; Cheng investigates refugee marriages and the difficulties men from various African nations face in seeking asylum in Hong Kong; and Wei analyzes Mainland Chinese queer reproduction that uses transnational Assisted Reproductive Technologies (ARTs) to enable queer parents to have a genetic link with their children and to be more accepted in Chinese society. In his essay, Petrus Liu pushes us to move beyond the idea that a theory of gender construction traveled to China from the West and was wholly adopted there, instead demonstrating the complexities of gender theories in China in the age of the Beijing Consensus. Christina Yuen Zi Chung and Sasha Su-Ling Welland explore a broad range of artworks that critically reflect on China’s efforts to create a China-centered global Global Intimacies: China and/in the Global South 252Preface trading network. Paul Amar offers a “deimperial queer analysis” of the all-time top-earning Chinese film, Wolf Warrior 2, illuminating how it both buttresses China’s extractive and militarized investments in African nations and manifests anti-imperialist and utopian impulses. Poems by Zhai Yongming and Xu Lizhi feature the gendered and sexualized precarity and violence of recent social transformations in China resulting from China’s intimate linkages with the global capitalist economy. Finally, Cai Yiping’s News and Views offers a nuanced engagement with the Chinese government’s formal proclamations on women’s rights.1 In the first essay, “Flexible Intimacies in the Global Intimate Economy : Evidence from Taiwan’s Cross-Border Marriages,” Mei-Hua Chen and Hong-zen Wang demonstrate the fallacy of treating cross-border marriages and cross-border sex work as separate as well as grouping women dichotomously under one or the other set of practices. These two seemingly disparate categories are, in effect, produced by state immigration regulations and dominant intersectional discourses of gender, sexuality, and class. Rather than distinguishing between marriage migrants and economic migrants, or between real marriages and fake marriages, Chen and Wang demonstrate the overlapping means by which women from the Global South try to better their lives in what they call the global intimate economy—where the Global North appropriates the reproductive and intimate labor of women from the Global South. The authors develop the concept of “flexible intimacy” to highlight how migrant women treat marriage as an investment through which to improve their lives. They argue that many marriage migrants have economic motivations for cross-border marriage and that migrant sex workers, conversely, are often involved in intimate relationships. Chen and Wang focus their study on Taiwan, which they argue is economically part of the North but politically part of the South due to Mainland China’s “One China” policy, which has marginalized Taiwan in the international political arena. To assert its sovereignty, the Taiwanese government 1. These essays grew out of a Ford Foundation-funded series of workshops on China and/in the Global South: The Central Role of Gender and Sexuality, which took place in Beijing and also at the University of California, Santa Cruz. Thanks to the Ford Foundation grants, and especially Susie Jolly, Lisa Rofel and the authors have built a transnational network of scholars and activists addressing China’s transformed presence in the Global South. Preface 253 strictly controls border crossings by migrant women from China and Southeast Asia yet simultaneously allows Taiwanese husbands to appropriate migrant women’s intimate and reproductive labor. Both Taiwanese men and migrant women expect... (shrink)

1. Xin yi shu chuang zuo lun, Xin yi shu lun ji -- 2. Mian xiang sheng huo, Lun yi shu de ji qiao -- 3. Yi yi dang shi -- 4. Xi wen le jian -- 5. Ge er bu ge -- 6. Lun Feng jie -- 7. Kai xin yue shi -- 8. Bu dao ding dian, Shen mei de min gan -- 9. Zai zai tan suo -- 10. Liao ran yu xin -- 11. Shen mei tan (...) -- 12. Si zeng xiang shi, Yi shen er ren -- 13. Shen mei xin tai -- 14. Hui jian zi ji -- 15. Diao su diao su -- 16. "Fu huo" de fu huo -- 17. Dong fang ji bai -- 18. Shen yu wu you -- 19. Tu na ying hua -- 20. Qu yu wu xie -- 21. Shu xin, ti ci xuan -- 22. Duan jian can pian. (shrink)

本书简要介绍了从明中叶至辛亥革命这一历史时期中国文化史上的主流思潮。全书按历史顺序分别评介了晚明人文主义思潮、明清之际启蒙主义思潮、嘉道之际实学思潮和19世纪末—20世纪初的新民思潮。.

Naïve realism is the view that veridical experiences are fundamentally relations of acquaintance to external objects and their features, and multidisjunctivism is the conjunction of naïve realism and the view that hallucinatory experiences don’t share a common fundamental kind. Multidisjunctivism allegedly removes the screening-off worry over naïve realism, and the relevant literature suggests that multidisjunctivism is one of the naïve realist responses to the worry. The present paper argues that the multidisjunctive solution is implicitly changing the subject, so the impression (...) that the multidisjunctivist is addressing the screening-off problem is illusory. (shrink)

Many philosophers believe that it counts against one morally if one is close and good friends with a bad person. Some argue that one acts badly by counting a bad person as a good friend, because such friendships carry significant moral risks. Others locate the moral badness in one’s moral psychology, suggesting that one becomes objectionably complacent by being good friends with a bad person. In this paper, I argue that none of these accounts are plausible. In fact, I propose (...) that the starting intuition, that there is something pro tanto morally bad in being close and good friends with a bad person, does not track ethical reality. A person’s friend list isn’t at all in-principle informative of a person’s moral character. I also diagnose why we nonetheless have this mistaken intuition. I propose that friendships are fragmented in two crucial aspects. Once we observe these fragmentations, our initially mistaken intuition completely goes away. (shrink)