The difference between us is very marked. Most that I have done and suffered in the service of our cause has been in public, and I have received encouragement at every step of the way. You on the o...

Science is continually faced with describing that which is beyond. This book, through contributions from nine prominent scholars, tackles that challenge.

In the Politics of Black Joy, Lindsey Stewart develops Hurston's contributions to political theory and philosophy of race by introducing the politics of joy as a refusal of neoabolitionism, a political tradition that reduces southern Black life to tragedy or social death.

As someone diagnosed with severe chronic mental illness early in my adolescence, I have spent over half of my life feeling out of step with the rest of the world due to hospitalizations, treatment programs, and the disruptions caused by anxiety, anorexia, depression, and obsessive–compulsive disorder. The effect of my mental health conditions compounded by these treatment environments means I often feel that I experience time passing differently, which results in sensations of removal and isolation from those around me. The (...) global shutdown caused by the COVID-19 pandemic seemed a way for normative bodies to experience the passing of time the way I always have. In this paper, I extend Dr. Sara Wasson’s analysis of the ways in which chronic pain resists narrative coherence to my own temporal experience of chronic mental illness, specifically my embodied experience of the pandemic. I use that embodied experience as a case study for examining how the reciprocal nature of time and narrativity, as outlined by Dr. Paul Ricoeur, can create isolation for those struggling with their temporality due to chronic mental illness. To acknowledge and grapple with the ramifications of discursive and material privilege involved in such situations, I include an analysis of Robert Desjarlais’s 1994 article “Struggling Along: The Possibilities for Experience among the Homeless Mentally Ill,” in which he investigates a similar phenomenon of being outside of structured sequential narrative time in the residents of a Boston shelter for the mentally ill. (shrink)

The article “On Rights of Inheritance and Bequest”, written by “Iain Brassington”, was originally published electronically on the publisher’s Internet portal on 23 April 2019 without open access.

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Christology and EthicsLindsey EsbensenChristology and Ethics Edited by F. Leron Shults and Brent Waters Grand Rapids, Mich.: Eerdmans, 2010. 231 pp. $28.00.This collection of essays is a welcome venture into the often-neglected relationship between Christology and ethics. The book stresses that the reciprocal relationship between Christology and Christian moral discernment needs greater attention as well as creative reformulation. The essays produce a variety of models of how other (...) disciplines provide the critical and constructive developments that can strengthen the bond between Christology and the Christian moral life. Rather than a definitive resolution to the “problem” of these Christian disciplines, the book is an invitation to further inquiry, an offer to join the conversation.Although the contributors to this anthology present disparate analyses, they share the goal of integrating interdisciplinary developments in the engagement of Christology and ethics. While each author shares similar departure points for these essays, the conclusions are vastly diverse for each contributor. This is in part because the essays draw from a broad range of sources, from the theological to the scientific. One chapter incorporates developments in the field of psychoanalysis in a discussion of the Christian emphasis on participation in the “new creation” through Jesus Christ, who is akin to the psychoanalytic “third” (121). Another chapter applies evolutionary epistemology and evolutionary ethics to a discussion of the ongoing social mediation and cultural reinterpretation of what it means to “do as Jesus did” (178). Underlying all the expositions is an affirmation that ethics and Christology mutually instruct and challenge each other (98). [End Page 211]Despite the integral connection among the essays, some underlying tensions remain. For instance, Brent Waters’s “The Incarnation and the Moral Life” strongly emphasizes the distinction between the civil community and the church, between the City of Man and the City of God (30). The church is the body of Christ that ministers to the world; therefore, “the singular ministry of the baptized engages, evangelizes, and orders the world in the name and under the authority of Jesus Christ” (21). All moral discernment outside of that with Christological foundations falls short of its goal. Conversely, Jan-Olav Henriksen’s “The Surprise of Judgment and Justice” suggests a much more inclusive view of non-Christian (and non-Christological) contributions to ethics in his interpretation of Matthew 25. Using the imago Dei as the springboard for his analysis, the world is envisioned as God’s gift, and the other (the neighbor) is the imago Dei who calls for recognition. Henriksen contends, “Because Christ is the true image of God, all of humanity is related to him, and is in some sense represented in him.... Christ is the face of every other human—as the one who calls us to mercy, compassion, and love” (142). Christian moral action, then, “is not only determined by you, it is determined by them and their calling of you” (141). In this sense, then, the church does not minister to the world, but the world ministers to the church in helping her to recognize the world as God’s gift and to see the image of God in the neighbor.While the emphases of the various proposals in this collection of essays may produce tensions, the strain is actually a positive contribution to the overall project. The anthology seeks to examine the most significant issues in the relationship between Christology and ethics without necessarily providing a conclusive resolution to how these disciplines mutually inform and reinforce each other. This collection of essays begins a conversation and invites further investigation of the various lines of inquiry.As with any anthology, each essay will have a greater or lesser appeal to the reader according to his interests. Nonetheless, this collection of essays is a unique contribution to systematic and moral theology, and it is an indispensable anthology for those pursuing Christology or ethics for their future endeavors. [End Page 212]Lindsey EsbensenUniversity of Notre DameCopyright © 2012 Society of Christian Ethics... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Diacritics 31.2 (2001) 85-97 [Access article in PDF] Reading's Reason Iain Morland [W]e must first of all recognize [...] how modes of reasoning that were once necessary can spring out of particular situations and be put to new tasks. —Michel de Certeau, Culture in the Plural Introduction: Reading after Reason? Reading is unreasonable. If, as Theodor Adorno has contended, to write poetry after Auschwitz is barbaric, then surely (...) reading—whether of poetry, philosophy, or newsprint—is doubly obscene ["Cultural Criticism" 34]. For Adorno, such barbarism means inattentiveness to barbaric historical truths; it is the misuse of rhetorical reflexivity for the perpetuation, rather than the critique, of social conditions. In other words: to write poetry after Auschwitz is to reproduce, and thereby implicitly condone, a contradictory society within which lyric verse and mass murder are coexistent. By extension, reading—as a pastime within the culture industry—appears to achieve nothing but the expression of such cultural reification. Reading is, as Adorno has written of criticism, "self-satisfied contemplation" in the face of systematized dissatisfaction ["Cultural Criticism" 34]. The Enlightenment had characterized reading as a process of educational reasoning, a dialogue with professional intellectuals about progress and truth. Although this idea carries a rather didactic undertone, as Michel de Certeau has pointed out ["Reading" 166-67], its representation of the book as a mobile repository of thought and criticism seems reasonable enough. Yet, in the face of such barbarism as Auschwitz, the practice of reading appears shamefully futile—a blindfolded refusal of historical truth, rather than an informed response to its implications.Reading is not alone in its unreasonableness: reason too has become unreasonable, Max Horkheimer has argued in Eclipse of Reason. Consequently, Horkheimer proposes that the "denunciation of what is currently called reason is the greatest service reason can render" [187]. Objective reason, Horkheimer suggests, has been eclipsed by its insipid, subjective counterpart, rationality. Rationality defines what is reasonable as what is useful; it does not seek truth as an end in itself. Reason has thus become merely a mental tool with which one can make effective plans in neocapitalist society. In short, rationality privileges means over ends. This subjective pastiche of reason, like poetry after Auschwitz, dumbly reiterates the status quo through devising ever more efficient procedures by which tasks may be carried out. It does not criticize the objective ends that are actually furthered by such procedures. Similarly, poetry (for example, that of James Fenton) invents ornate and affective representations of modern barbarism without removing the conditions within which barbarism thrives. In this regard, reading is [End Page 85] the negative counterpart of Adorno's "dialectical critic of culture," who "both participate[s] in culture and [does] not participate" ["Cultural Criticism" 33]: reading seems to be uncritical for the same reasons that a cultural commentator is critical.The valorization of procedure, of means over ends, is why the practice of reading seems complacently to ignore the demands of society and culture. Insofar as rationality considers reasonable only those procedures that have instant, efficient results, reading remains in essence unreasonable. Reading is not a procedure whereby certain tasks may be accomplished—whether ethical demands for political change, or capitalist invitations to unlimited consumerism. Put differently, although reading has consequences, there is no procedural connection between the practice of reading and its consequences. Consider the case of ethical demands: reading may certainly serve as a preparation or grounding for future political activity. However, such preparatory reading is inevitably superseded by the activity that it incites. It is not itself a procedure for political change, but simply part of the means to a political end. This situation is mirrored in the opposite case, that of capitalist enticement: reading interrupts bookselling. A consumer's reading time extends indeterminably beyond the moment of expenditure, unlike their usage of a product with a predetermined life span.Likewise, when I wrote in the opening paragraph that it "seems reasonable enough" that a book ought to be a repository of thought and criticism, I too have employed reason in merely a rational sense. I have defined the process of reading a book as reasonable only if... (shrink)

This article explores the extent to which consumers consider ethics in luxury goods consumption. In particular, it explores whether there is a significant difference between consumers’ propensity to consider ethics in luxury versus commodity purchase and whether consumers are ready to purchase ethical-luxury. Prior research in ethical consumption focuses on low value, commoditized product categories such as food, cosmetics and high street apparel. It is debatable if consumers follow similar ethical consumption patterns in luxury purchases. Findings indicate that consumers’ propensity (...) to consider ethics is significantly lower in luxury purchases when compared to commoditized purchases and explores some of the potential reasons for this reduced propensity to identify or act upon ethical issues in luxury consumption. (shrink)

Nuclear bodies contribute to non‐random organization of the human genome and nuclear function. Using a major prototypical nuclear body, the Cajal body, as an example, we suggest that these structures assemble at specific gene loci located across the genome as a result of high transcriptional activity. Subsequently, target genes are physically clustered in close proximity in Cajal body‐containing cells. However, Cajal bodies are observed in only a limited number of human cell types, including neuronal and cancer cells. Ultimately, Cajal body (...) depletion perturbs splicing kinetics by reducing target small nuclear RNA (snRNA) transcription and limiting the levels of spliceosomal snRNPs, including their modification and turnover following each round of RNA splicing. As such, Cajal bodies are capable of shaping the chromatin interaction landscape and the transcriptome by influencing spliceosome kinetics. Future studies should concentrate on characterizing the direct influence of Cajal bodies upon snRNA gene transcriptional dynamics.Also see the video abstract here. (shrink)

In “Post-Liberation Feminism,” Ladelle McWhorter raises the question of what practices will be helpful to further feminist goals if we are no longer in a state of domination, but are still oppressed. McWhorter finds resources in Michel Foucault's concept of “practices of freedom” to begin to answer this question. I build upon McWhorter's insight while recalling Angela Davis's Blues Legacies and Black Feminism: namely, that sexual love, as conceived in hoodoo and the blues, became a terrain upon which newly emancipated (...) blacks worked out what their newfound freedom meant. In this essay, I consider what practices of freedom would look like within a life-giving nexus of hoodoo, blues, and sexual love. Not only does the image of the hoodoo woman, prevalent within the blues, emerge through an interaction of race, class, region, gender, sexuality, and spiritualty, but analyzing sexual love within this hoodoo–blues coupling will help us track how sexual love was transformed into a practice of freedom. I will argue that sexual love within this hoodoo–blues coupling reveals an important dimension of emancipatory work that both defies categorization as resistance and is crucial to the development of capacities for resistance. (shrink)

abstract It is standardly taken for granted in the literature on the morality of abortion that adoption is almost always an available and morally preferable alternative to abortion — one that does the same thing so far as parenthood is concerned. This assumption pushes proponents of a woman's right to choose into giving arguments that are based almost exclusively around the physicality of pregnancy and childbirth. On the other side of the debate, the assumption that adoption is a real alternative (...) seems to strengthen the contention that a woman who wishes to abort is morally deficient, whatever the status of the foetus: that she is selfish or short‐sighted in her refusal to bear the temporary physical burden of pregnancy. In this article, I will argue that adoption is not a genuine alternative to abortion. It does not ‘do the same thing’, even setting aside the physicality of pregnancy. I will show that on the most successful model of parental obligation — a causal account that formalises the distinction between parent: progenitor, and parent: carer — birth mothers and fathers remain obliged, life‐long, to their birth children even when the child is adopted out. (shrink)

At the intersection of metaphysics and social theory, this book presents and examines Adorno's unusual concept of possibility and aims to answer how we are to articulate the possibility of a redeemed life without lapsing into a vague and naïve utopianism.

The Declaration of Helsinki and the Council of the International Organization of Medical Sciences provide guidance on standards of care and prevention in clinical trials. In the current and increasingly challenging research environment, the ethical status of a trial design depends not only on protection of participants, but also on social value, feasibility, and scientific validity. Using the example of a study assessing efficacy of a vaccine to prevent human papilloma virus in HIV-1 infected adolescent girls in low resource countries (...) without access to the vaccine, we compare several trial designs which rank lower on some criteria and higher on others, giving rise to difficult trade-offs. This case demonstrates the need for developing more nuanced guidance documents to help researchers balance these often conflicting criteria. (shrink)

Heidegger, Art, and Postmodernity offers a radical new interpretation of Heidegger's later philosophy, developing his argument that art can help lead humanity beyond the nihilistic ontotheology of the modern age. Providing pathbreaking readings of Heidegger's 'The Origin of the Work of Art' and his notoriously difficult Contributions to Philosophy, this book explains precisely what postmodernity meant for Heidegger, the greatest philosophical critic of modernity, and what it could still mean for us today. Exploring these issues, Iain D. Thomson examines (...) several postmodern works of art, including music, literature, painting and even comic books, from a post-Heideggerian perspective. Clearly written and accessible, this book will help readers gain a deeper understanding of Heidegger and his relation to postmodern theory, popular culture and art. (shrink)

This paper reports on a study of ethical decision-making in a fair trade company. This can be seen to be a crucial arena for investigation since fair trade firms not only have a specific ethical mission in terms of helping growers out of poverty, but they tend to be perceived as (and are often marketed on the basis of) having an "ethical" image. Eschewing a straightforward test of extant ethical decision models, we adopt Thompson''s proposal for a more contextualist understanding (...) rooted in ethnographic data. Our findings suggest that the fair trade mission of the firm is experienced as an over-riding ethical claim, which is often invoked to justify potentially ethically questionable decisions. Moreover, decision precedents emerge which can mean that the decision process is bypassed or hurried through. Finally we provide evidence that the significance of these precedents, and indeed, even moral intensity itself, could be actively shaped and constructed by organization members to support different, even shifting, conceptions of what is a morally acceptable decision for a fair trade company to make. (shrink)

In Kant and the Role of Pleasure in Moral Action, Iain Morrisson offers a new view on Kant’s theory of moral action.

We have never been so aware of masks. They were in short supply in the early days of COVID-19, resulting in significant risk to health care workers. Now they are highly politicized with battles about mask-wearing protocols breaking out in public. Although masks have obtained a new urgency and ubiquity in the context of COVID-19, people have thought about both the literal and metaphorical role of masks in medicine for generations. In this paper, we discuss three such metaphors—the masks of (...) objectivity, of infallibility, and of benevolence—and their powerful role in medicine. These masks can be viewed as inflexible barriers to communication, contributing to the traditional authoritarian relationship between doctor and patient and concealing the authenticity and vulnerability of physicians. COVID masks, by contrast, offer a more nuanced and morally complex metaphor for thinking about protecting people from harm, authentic and trustworthy communication, and attention to potential inequities both in and beyond medical settings. We highlight the morally relevant challenges and opportunities that masks evoke and suggest that there is much to be gained from rethinking the mask metaphor in medicine. (shrink)

Iain Atack identifies the contribution of nonviolence to political theory through connecting central characteristics of nonviolent action to fundamental debates about the role of power and violence in politics. This in turn provides a platform for going beyond historical and strategic accounts of nonviolence to a deeper understanding of its transformative potential. From Mahatma Gandhi and Martin Luther King to toppled communist regimes in Eastern Europe and pro-democracy movements in Serbia, Georgia and Ukraine, nonviolent action has played a significant (...) role in achieving social and political change in the last century. The Arab Spring revolutions, particularly those in Tunisia and Egypt, and the Occupy movement in the US and UK demonstrate that nonviolence continues to be a vital feature of many campaigns for democracy, human rights and social justice. (shrink)

Iain I remember reading Thomas Jefferson in high school; he wrote so eloquently about our human need for freedom that I got choked up just reading him. When I found out he'd had slaves I was stunned, traumatized intellectually, but I lacked the resources to work through it very far at the time. Reading Heidegger a few years later I had a similar experience, only magnified and more complicated. As I read Heidegger's later work in Hubert Dreyfus's wonderful "later (...) Heidegger" course at UC Berkeley, I had that strange experience Emerson describes as our own ideas returning to us with "alienated majesty"; here, I thought, was someone who had eloquently expressed ideas that I felt were at the core of my own thinking but that I had never managed to articulate adequately. I was deeply moved by Heidegger's critique of our increasingly nihilistic treatment of our world and each other as meaningless resources to be optimized and I was inspired by his vision of poetic thinking as a way out of this historical nihilism. Then I found out he'd been a Nazi. I was intellectually traumatized once again. But this time I didn't let the question go: How could the greatest thinker of the twentieth century have thrown the weight of his thinking behind its most horrible political regime? That's something I've been struggling with for almost twenty years now. I believe I made some real progress in understanding this difficult and controversial issue in Heidegger on Ontotheology: Technology and the Politics of Education, and I hope to disseminate the view I presented there to a broader audience in a book I'm working on now, an intellectual biography of Heidegger. (shrink)

The consent theory of power, whereby ruling elites depend ultimately on the submission, cooperation and obedience of the governed as their source of power, is often linked to debates about the effectiveness of non-violent political action. According to this theory, ruling elites depend ultimately on the submission, cooperation and obedience of the governed as their source of power. If this cooperation is with-drawn, then this power is undermined. Iain Atack outlines this theory and examines its strengths and weaknesses. Atack (...) argues that incorporating the insights of other theories of power, such as Gramsci's theory of hegemony and Foucault's views on 'micro-power', can provide us with a more sophisticated understanding of both the effectiveness and the limits of nonviolent political action than the consent theory of power. Gramsci's contribution deepens the analysis in terms of our understanding of the origins of individual consent in the context of larger economic and political structures, while Foucault adds a different dimension, in that his micro-approach emphasizes the ubiquity and plurality of power, rather than its embodiment or reification in large-scale structures. (shrink)

In this paper I present a critical analysis of the English law relating to the safeguarding of vulnerable adults, in particular how the law impacts on the sexual lives of adult women with mental disabilities. I consider the discourses of vulnerability that surround the different legal regimes and whether the emerging theoretical vulnerability literature can assist in developing more nuanced legal responses. I argue that the inherent jurisdiction and Care Act 2014 provide an opportunity to move away from the focus (...) on inherent features of vulnerability such as mental disability towards a more nuanced, situational and embodied account of what it means to safeguard ‘vulnerable adults’. This has the potential to be developed in England through the new legal framework of the Care Act and can be achieved through targeting interventions against the situational causes of vulnerability, for example the perpetrators of sexual violence. (shrink)

Many critics of the legalization of physician‐assisted death oppose it in part because they fear it will further disadvantage those who are already economically disadvantaged. This argument points to a serious problem of how economic considerations can influence medical decisions, but in the context of PAD, the concern is not borne out. We will provide empirical evidence suggesting that concerns about money influence medical decisions throughout the full course of illness, but at the end of life, financial pressure is much (...) more likely to influence a decision to pursue or reject aggressive life‐extending care than it is to influence a request for PAD. We will also address the question of whether financial pressure as a result of being poor—particularly in the context of an inadequate social safety net—robs people of their autonomy, rendering their informed request and consent invalid. We argue that it does not. We will emphasize the impracticality and injustice of rejecting the role of poverty as a legitimate factor in decision‐making, the irrational distinction between PAD and withdrawal of life‐sustaining care, and the more appropriate focus on the great flaws in the American health care system. (shrink)

Canonical economic agents act so as to maximize a single, representative, utility function. However, there is accumulating evidence that heterogeneity in thought processes may be an important determinant of individual behavior. This paper investigates the implications of a vector-valued generalization of the Expected Utility paradigm, which permits agents either to deliberate as per Homo economics, or to act impulsively. This generalized decision theory is applied to explain the crowding-out effect, irrational educational investment decisions, persistent social inequalities, the pervasive influence of (...) non-cognitive ability on socio-economic outcomes, and the dynamic relationships between non-cognitive ability, cognitive ability, and behavioral biases. These results suggest that the generalized decision theory warrants further investigation. (shrink)

This paper investigates the difficulties of creating economic, social, and environmental values when operating as a hybrid venture. Drawing on hybrid organizing and sustainable business model research, it explores the implications of alternative forms of business model experimented with by farmer owned, fairtrade social enterprise Cafédirect. Responding to changes and challenges in the market and societal environment, Cafédirect has tried multiple business model innovations to deliver on all three forms of value capture, with differing levels of success. This longitudinal case (...) study, therefore, provides a contribution to our understanding of how business models enact hybrid mission, providing a platform for triple-bottom-line value capture. In doing so, we are able to expand on the normative understandings of integrating hybrid objectives, and the complications of multiple types of value capture. (shrink)

What attitude would a just state take to the inheritance of property? Would confiscatory taxes on the estate of the deceased be morally acceptable, or would they represent some kind of wrong? While there is a good amount of political philosophical scholarship that considers the desirability of inheritance tax, there appears to be little that has considered it from the perspective of rights theory, asking what kind of thing a right to bequeath or to inherit would be, and whether those (...) putative rights are defeasible. I argue here that putative inheritance rights are best made sense of as interest-rights. However, while agents may have interests in bequest and inheritance, it is also plausible that the community as a whole has interests that would be served by a confiscatory inheritance tax; and if inheritors’ and testators’ interests are strong enough to generate a prima facie right, it is also plausible that the community would have a competing prima facie right. Importantly, there is reason to think that the community’s interests trump the testator’s and the inheritor’s; if there are thoroughgoing rights in respect of inheritance, it is not at all clear that a highly confiscatory tax would violate them. (shrink)

Heidegger is now widely recognized as one of the most influential and controversial philosophers of the twentieth century, yet much of his later philosophy remains shrouded in confusion and controversy. Restoring Heidegger's understanding of metaphysics as 'ontotheology' to its rightful place at the center of his later thought, this book demonstrates the depth and significance of his controversial critique of technology, his appalling misadventure with Nazism, his prescient critique of the university, and his important philosophical suggestions for the future of (...) higher education. It will be required reading for those seeking to understand the relationship between Heidegger's philosophy and National Socialism, as well as the continuing relevance of his work. (shrink)

Heidegger is against the modern tradition of philosophical “aesthetics” because he is for the true “work of art” which, he argues, the aesthetic approach to art eclipses. Heidegger's critique of aesthetics and his advocacy of art thus form a complementary whole. Section 1 orients the reader by providing a brief overview of Heidegger's philosophical stand against aesthetics, for art. Section 2 explains Heidegger's philosophical critique of aesthetics, showing why he thinks aesthetics follows from modern “subjectivism” and leads to late-modern “enframing,” (...) historical worldviews Heidegger seeks to transcend from within—in part by way of his phenomenological interpretations of art. Section 3 clarifies this attempt to transcend modern aesthetics from within, focusing on the way Heidegger seeks to build a phenomenological bridge from a particular work of art by Vincent van Gogh to the ontological truth of art in general. In this way, as we will see, Heidegger seeks to show how art can help lead us into a genuinely meaningful postmodern age. Section 4 concludes by explaining how this understanding of Heidegger's project allows us to resolve the longstanding controversy surrounding his interpretation of Van Gogh. (shrink)

Language plays a role in the genocide of the Rohingya people in Myanmar and continues to shape their experiences in displacement, yet their linguistic rights are rarely discussed in relation to their human rights and humanitarian concerns. International human rights standards offer important foundations for conceptualizing the “right to language” and identifying how linguistic rights can be violated both in situ and in displacement. The Rohingya case highlights how language policies are weaponized to oppress unwanted minorities; their outsider status is (...) reinforced by the country’s language education policy and they face additional rights challenges in displacement—including obstacles to effectively accessing humanitarian aid. Moving forward, norms associated with self-determination and language rights offer a conceptual foundation for shifting attitudes and altering negative perceptions of Rohingya identity. (shrink)

In ‘After-birth abortion: why should the baby live?’, Giubilini and Minerva argue that infanticide should be permitted for the same reasons as abortion. In particular, they argue that infanticide should be permitted even for reasons that do not primarily serve the interests (or would-be best interests) of the newborn. They claim that abortion is permissible for reasons that do not primarily serve the interests (or would-be interests) of the fetus because fetuses lack a right to life. They argue that newborns (...) also lack a right to life, and they conclude that therefore, the same reasons that justify abortion can justify infanticide. This conclusion does not follow. The lack of a right to life is not decisive. Furthermore, the justificatory power of a given reason is a function of moral context. Generalisations about reasons across dissimilar moral contexts are invalid. However, a similar conclusion does follow—that fetus-killing and newborn-killing are morally identical in identical moral contexts—but this conclusion is trivial, since fetuses and newborns are never in identical moral contexts. (shrink)

Chemokines (chemotactic cytokines) drive and direct leukocyte traffic. New evidence suggests that the unusual CCR6/CCL20 chemokine receptor/ligand axis provides key homing signals for recently identified cells of the adaptive immune system, recruiting both pro‐inflammatory and suppressive T cell subsets. Thus CCR6 and CCL20 have been recently implicated in various human pathologies, particularly in autoimmune disease. These studies have revealed that targeting CCR6/CCL20 can enhance or inhibit autoimmune disease depending on the cellular basis of pathogenesis and the cell subtype most affected (...) through different CCR6/CCL20 manipulations. Here, we discuss the significance of this chemokine receptor/ligand axis in immune and inflammatory functions, consider the potential for targeting CCR6/CCL20 in human autoimmunity and propose that the shared evolutionary origins of pro‐inflammatory and regulatory T cells may contribute to the reason why both immune activation and regulation might be controlled through the same chemokine pathway. (shrink)