Mitchell's formulation of the chemiosmotic theory of oxidative phosphorylation in 1961 lacked any experimental support for its three central postulates. The path by which Mitchell reached this theory is explored. A major factor was the role of Mitchell's philosophical system conceived in his student days at Cambridge. This system appears to have become a tacit influence on his work in the sense that Polanyi understood all knowledge to be generated by an interaction between tacit and explicit knowing. Early in his (...) life Mitchell had evolved a simple philosophy based on fluctoids, fluctids and statids which was developed in a thesis submitted for the Ph.D. at the University of Cambridge, England. This aspect of his work was rejected by the examiners and became a tacit element in his intellectual development. It is argued from his various publications that this philosophy can be traced as an underlying theme behind much of Mitchell's theoretical writing in the 50's leading, through his notion of vectorial metabolism, to the formulation and amplification of the chemiosmotic theory in the sixties. This philosophy formed the basis for Mitchell of his understanding of biological systems and gave him his unique approach to cell biology. (shrink)

I argue that ‘Moore’s paradox for God’. I do not believe this proposition shows that nobody can be both omniscient and rational in all her beliefs. I then anticipate and rebut three objections to my argument.

In this journal, Hamid Vahid argues against three families of explanation of Moore-paradoxicality. The first is the Wittgensteinian approach; I assert that p just in case I assert that I believe that p. So making a Moore-paradoxical assertion involves contradictory assertions. The second is the epistemic approach, one committed to: if I am justified in believing that p then I am justified in believing that I believe that p. So it is impossible to have a justified omissive Moore-paradoxical belief. The (...) third is the conscious belief approach, being committed to: if I consciously believe that p then I believe that I believe that p. So if I have a conscious omissive Moore-paradoxical belief, then I have contradictory second-order beliefs. In their place, Vahid argues for the defective-interpretation approach, broadly that charity requires us to discount the utterer of a Moore-paradoxical sentence as a speaker. I agree that the Wittgensteinian approach is unsatisfactory. But so is the defective-interpretation approach. However, there is a satisfactory version of each of the epistemic and conscious-belief approaches. (shrink)

I argue that Moore's propositions, for example, 'I went to the pictures last Tuesday but I don't believe that I did' cannot be rationally believed. Their assertors either cannot be rationally believed or cannot be believed to be rational. This analysis is extended to Moorean propositions such as God knows that I am an atheist and I believe that this proposition is false. I then defend the following definition of assertion: anyone asserts that p iff that person expresses a belief (...) that p with the intention of causing relevant epistemic change in the cognition of an actual or potential audience. (shrink)

While Saint Augustine has been a household name for centuries, the same cannot be said of long-overlooked philosopher John Poinsot. But in _Augustine and Poinsot_, John Deely contends that the history of semiotics cannot be conceived of without Poinsot’s landmark contribution. According to Deely, even though Augustine was the first to describe _what_ the sign does, Poinsot was the first to show _how_ the sign mediates between nature and culture. This revolutionary volume demonstrates how Poinsot’s account of semiotics (...) allows us to produce human knowledge and experience. (shrink)

This book sets out for the first time in English and in the terms of modern logic the semantics of the Port Royal Logic of Antoine Arnauld and Pierre Nicole, perhaps the most influential logic book in the 17th and 18th centuries. Its goal is to explain how the Logic reworks the foundation of pre-Cartesian logic so as to make it compatible with Descartes' metaphysics. The Logic's authors forged a new theory of reference based on the medieval notion of objective (...) being, which is essentially the modern notion of intentional content. Indeed, the book's central aim is to detail how the Logic reoriented semantics so that it centered on the notion of intentional content. This content, which the Logic calls comprehension, consists of an idea's defining modes. Mechanisms are defined in terms of comprehension that rework earlier explanations of central notions like conceptual inclusion, signification, abstraction, idea restriction, sensation, and most importantly within the Logic's metatheory, the concept of idea-extension, which is a new technical concept coined by the Logic. Although Descartes is famous for rejecting "Aristotelianism," he says virtually nothing about technical concepts in logic. His followers fill the gap. By putting to use the doctrine of objective being, which had been a relatively minor part of medieval logic, they preserve more central semantic doctrines, especially a correspondence theory of truth. A recurring theme of the book is the degree to which the Logic hews to medieval theory. This interpretation is at odds with what has become a standard reading among French scholars according to which this 16th-century work should be understood as rejecting earlier logic along with Aristotelian metaphysics, and as putting in its place structures more like those of 19th-century class theory. (shrink)

I argue that there are living and everyday case in which rationality requires you, as a non-idealized human thinker, to have inconsistent beliefs while recognizing the inconsistency. I defend my argument against classical and insightful objections by Doris Olin, as well as others. I consider three versions of the preface paradox as candidate cases, including Makinson’s original version. None is free from objection. However, there is a fourth version, Modesty, that supposes that you believe that at least one of your (...) beliefs is false. I argue that this version escapes all the objections that could trouble the other versions, including the objection that given certain closure principles for justified belief, justified inconsistent beliefs saddle you with a pair of justified beliefs that are in explicit contradiction. I also argue more tentatively for the same verdict for Modesty*, a version that supposes that you believe that at least one of your beliefs is false. In that case, your belief guarantees that its content is true, in which case your beliefs are inconsistent, because at least one of them must be false. Once you think you’re wrong, you must be right! Crucial to my argument is a distinction between explicitly contradictory beliefs and three forms of inconsistency in belief. In the first of these, you believe contingent propositions each of which is logically independent of the others, yet you also believe the syntactic negation of their conjunction. In the second, your beliefs are inconsistent because of the rigid designation of demonstratives such as ‘this’ embedded in their contents. In the third, as in Modesty and Modesty* your beliefs are inconsistent because of self-reference. (shrink)

In 2004, I explained the absurdity of Moore-paradoxical belief via the syllogism (Williams 2004): (1) All circumstances that justify me in believing that p are circumstances that tend to make me believe that p. (2) All circumstances that tend to make me believe that p are circumstances that justify me in believing that I believe that p. (3) All circumstances that justify me in believing that p are circumstances that justify me in believing that I believe that p. I then (...) took (3) to mean (EP) Whatever justifies me in believing that p justifies me in believing that I believe that p.1 Now suppose that I am justified in believing anything of the omissive Mooreparadoxical form: (Om) p and I do not believe that p. Then I am justified in believing the first conjunct. So by (EP) I am justified in believing that I believe that p. But since I am also justified in believing the second conjunct, I am justified in believing that I do not believe that p. I claimed that this is impossible, because anything that justifies me in believing that something is the case renders me unjustified in believing that it is not the case. This syllogism is plausible from an externalist view of justification, according to which circumstances such as seeming to see rain under normal perceptual conditions, justify me in believing that it is raining. In support of (1), if my apparent perceptions of rain are reliably connected with rain, so as to justify me in thinking that it is raining, they also tend to make me believe that it is raining. In support of (2), my apparent perceptions of rain are also reliably connected with my coming to believe that it is raining. However, Anthony Brueckner (2006) argues that (1) and (EP) are both false once justification is thought of evidentially. Against (EP), he claims that my evidence that p is not evidence that I believe that p unless I possess the evidence, in the sense that I believe it and were I to believe that p on its basis. (shrink)

This paper explores the modal interpretation of ?ukasiewicz's n -truth-values, his conditional and the puzzles they generate by exploring his suggestion that by ?necessity? he intends the concept used in traditional philosophy. Scalar adjectives form families with nested extensions over the left and right fields of an ordering relation described by an associated comparative adjective. Associated is a privative negation that reverses the ?rank? of a predicate within the field. If the scalar semantics is interpreted over a totally ordered domain (...) of cardinality n and metric ?, an n-valued Lukasiewicz algebra is definable. Privation is analysed in terms of non-scalar adjectives. Any Boolean algebra of 2 n ?properties? determines an n + 1 valued Lukasiewicz algebra. The Neoplatonic ?hierarchy of Being? is essentially the order presupposed by natural language modal scalars. ?ukasiewicz's ≈ is privative negation, and ? proves to stand for the extensional (antitonic) dual if ? then for scalar adjectives, especially modals. Relations to product logics and frequency interpretations of probability are sketched. (shrink)

G. E. Moore famously observed that to assert ‘I went to the pictures last Tuesday but I do not believe that I did’ would be ‘absurd’. Moore calls it a ‘paradox’ that this absurdity persists despite the fact that what I say about myself might be true. Krista Lawlor and John Perry have proposed an explanation of the absurdity that confines itself to semantic notions while eschewing pragmatic ones. We argue that this explanation faces four objections. We give a (...) better explanation of the absurdity both in assertion and in belief that avoids our four objections. (shrink)

Eventually and inevitably the study of a Roman comedy leads to the question of its relationship to the Greek model and to the nature of the original play. In recent years Terence's Adelphoe has stimulated numerous publications on the Menandrian comedy and on the changes which were made by the Latin dramatist. Greatest attention has been paid to the ending of the Greek play. This article, however, will examine the first two ‘acts’ of the Terentian comedy and will offer a (...) reconstruction of its primary model that differs from those that have been proposed in the major studies on this problem. (shrink)

ABSTRACT Timothy Williamson offers the ordinary practice, the lottery and the Moorean argument for the ‘knowledge account’ that assertion is the only speech-act that is governed by the single rule that one must know its content. I show that these fail to support it and that the emptiness of the knowledge account renders mysterious why breaking the knowledge rule should be a source of criticism. I argue that focussing exclusively on the sincerity of the speech-act of letting one know engenders (...) a category mistake about the nature of constraints on assertion. After giving an analysis of assertion I propose that the norm of a type of assertion is the epistemic state one needs for one’s speech-act to succeed in being an assertion of that type and that the epistemic state in question is determined by the point of the type of assertion. One is practically irrational in violating the norm. (shrink)

It is first argued that there are two types of beliefs-in; beliefs in X which are identical with the belief that X exists and beliefs-in which entail no existential belief but which do entail a commendatory attitude. It is then shown that belief in God is not identical with, but rather entails, the belief that God exists. Pace Norman Malcolm, the converse holds neither as a logical nor psychological claims.

Discussions of what is sometimes called 'Moore's paradox' are often vitiated by a failure to notice that there are two paradoxes; not merely one in two sets of linguistic clothing. The two paradoxes are absurd, but in different ways, and accordingly require different explanations.

The mediaeval logic of Aristotelian privation, represented by Ockham's expositionof All A is non-P as All S is of a type T that is naturally P and no S is P, iscritically evaluated as an account of privative negation. It is argued that there aretwo senses of privative negation: (1) an intensifier (as in subhuman), the dualof Neoplatonic hypernegation (superhuman), which is studied in linguistics asan operator on scalar adjectives, and (2) a (often lexicalized) Boolean complementrelative to the extension of (...) a privative negation in sense (1) (e.g., Brute). Thissecond sense, which is the privative negation discussed in modern linguistics, isshown to be Aristotle's. It is argued that Ockham's exposition fails to capture muchof the logic of Aristotelian privation due to limitations in the expressive power of thesyllogistic. (shrink)

Adam Morton recently argued that the Ramsey test of whether we may accept a conditional as true embodies a misunderstanding of the function of indicative conditionals. I attack the Ramsey Test for different reasons; there are conditionals that we should accept as true that the Ramsey Test tells us to reject and there are conditionals that we should reject that the Ramsey Test tells us to accept.

In these lines Micio criticizes the way in which his brother Demea rears his son and implies comparison with his own method. Two types of imperium are contrasted, ‘imperium ’ and ‘illud quod amicitia adiungitur’. It is the latter phrase which will be discussed here. If this meant ‘si imperium tibi amicitia adiungas’, there would be no difficulty: cf. Cic. Mur. 41 ‘benevolentiam adiungit lenitate audiendi’; Sext. Rose. 116 ‘auxilium sibi se putat adiunxisse.’ The acquisition of imperium, however, is not (...) relevant here; Micio is talking of the imperium that a man has qua father and the point at issue is the manner in which each man administers this imperium. (shrink)

Neither novel should be read as predictions, the accuracy of which can be used to judge them. Rather, both attempt to portray what humanity could conceivably become. The authenticity of this conceivability is a necessary condition of the power of both works to raise central philosophical questions about the human condition. What is ethically wrong with control? How far can Man go in recreating himself? In what sense are these worlds anti-utopian? Are they really possible worlds? How credible are they (...) as political systems? In what ways do the different systems depict the end of humanity? What logical and moral objections could be made against their fictional apologists? (shrink)

This book shows otherwise. John Martin rehabilitates Neoplatonism, founded by Plotinus and brought into Christianity by St. Augustine.

“The real issue concerns the need for authentic and representative black leadership being included within the highest levels of the legislative decision-making of South Africa. Apart from this, all other overtures for change would be void.”.

Ondanks de grote diversiteit van Berlins werken, die een groot cultuurhistorisch bereik hebben, gaat hij uit van een moreel minimum als constante horizon van de mensheid, ondanks alle culturele verschillen.