The Diagnosis Confirmation Model includes a dual-pricing mechanism designed to support value-based pricing of novel antibiotics while improving the alignment of financial incentives with their optimal use in patients at high risk of drug-resistant infections. DCM is a market-based model and complementary to delinked models. Policymakers interested in stimulating antibiotic innovation could consider tailoring the DCM to their reimbursement systems and incorporating it into the suite of incentives to improve the economics of antibiotics.

The need for new “pull” incentives to stimulate antibiotic R&D is widely recognized. Due to the global diversity of health systems, combined with different challenges faced by antibiotics used in different types of healthcare settings, there is no one-size-fits-all solution. Instead, different “pull” incentives should be tailored to local contexts, priorities, and antibiotic types. Policymakers and industry should collaborate to identify appropriate solutions at the local, regional, and global levels.

Philosophy, Iranian. ; Mysticism -- Iran. ; Islamic philosophy--Iran. ; Philosophers -- Iran.

It is sometimes said that there has been a ‘paradigm shift’ in the field of assessment over the last two or three decades: a new preoccupation with what learners can do, what they know or what they have achieved. It is suggested in this article that this change has precipitated a need to distinguish two conceptually and logically distinct methodological approaches to assessment that have hitherto gone unacknowledged. The upshot, it is argued, is that there appears to be a fundamental (...) confusion at the heart of current policy, a confusion occasioned by the demand to know what learners know and compounded by a failure to recognise what this properly entails for assessment methodology. (shrink)

The last decade or so has seen a resurgence of interest in Ryle's knowing‐how / knowing‐that (KH/KT) distinction, prompted by Stanley and Williamson's provocative intellectualist reading of the distinction. This chapter argues that even by Ryle's own account the distinction cannot properly be regarded as an epistemological distinction, that is, as demarcating two different kinds of knowledge. It talks about being clear about where our use of the KH/KT distinction does make sense and where it doesn't. More specifically, it leaves (...) us incapable of explaining how we are able to distinguish cases perhaps identical in terms of overt behaviour yet seemingly very different in terms of what is known. Although the KH/KT distinction has some limited viability in the context of knowledge attribution it is simply not viable as an epistemological distinction. (shrink)

Alzheimer’s disease is emerging into public view in unprecedented ways. Foremost among these is the embodied form of elderly men and women appearing in commercial imagery for patient advocacy groups or pharmaceutical advertisements, but scientific imagery also seeps into the visual media cultures that surround us. The recent reconfiguration of Alzheimer’s disease is due to expanding ageing populations, an aggressive biopharmaceutical industry becoming a fast-growing material-semiotic realm that is providing powerful images of both gendered and racialized embodiment. Such a visual, (...) and yet highly material, realm is in need of feminist interventions, engaging with the images and ideas that circulate around ageing, medicine, human and non-human embodiment. From a non-representationalist and posthumanist perspective identified as feminist visual studies of technoscience, the authors seek to further the discussion in the direction of understanding the ‘scattered ontologies’ of Alzheimer’s — in laboratory practice, the realm of medical media and in commercial appeals to coherent individuality and human cognition — as gendered domains of figural reality and performative matter. (shrink)

While geocentric and relative frames of reference have figured prominently in the literature on spatial language and cognition, the intrinsic frame of reference has received less attention, though various subtypes of the intrinsic frame have been proposed. This paper presents a revised classification of the intrinsic frame, distinguishing between three subtypes: a ‘direct’ subtype, an ‘object-centered’ subtype and a ‘figure-anchored’ subtype, with a cross-cutting distinction between ‘function-based’ and ‘shape-based’ systems. In addition, the ‘FIBO’ system in Dhivehi is analyzed as an (...) example of a borderline case, with some important features of the intrinsic frame but also some differences, presenting a challenge for existing frame of reference classifications. The rotational properties of these various systems are also considered. The analysis underscores the considerable diversity within intrinsic systems but also points to a closer relationship between intrinsic and extrinsic frames than has previously been appreciated. This may have implications for broader theoretical issues including how frames of reference are acquired, how speech communities come to use different frames and whether patterns of frame use in discourse shape patterns of non-verbal frame use. (shrink)

For years, tour guide Daniel Lum has brought visitors as well as his children out to the remote corners of Barrow, Alaska, one of the northernmost cities in the world, to witness polar bears and walrus on the dark, sandy beaches. Over time, snapping pictures for tourists and shooting photographs of his own, he has been a first-hand witness to the profound environmental changes taking place as his homeland shifts and disappears before his eyes. As arguments over climate change rage (...) in more temperate locales, Nuvuk, the Northernmost is a poignant snapshot of life in a town where these changes are impossible to overlook. Lum's vivid photographs of wildlife, such as whales, polar bears, and birds, offer rare close-ups of animals few ever see. In addition, Lum provides vivid descriptions and pictures of daily life in and around Barrow, offering a compelling insider's introduction to living on the tip of the world. With Lum as a capable guide, Nuvuk, the Northernmost is a chance to see a rare world before it changes forever. (shrink)

Seven speeches on sufism. ʻAbd Allāh ibn Muḥammad ʻAyn al-Quḍāh al-Hamadhānī, -1131.

Critical study on Advaitatattvasudhā by N. S. Anantakrishna Sastri, work on Advaita Philosophy.

The relationship between humans and animals is complex and influenced by multiple variables. Humans display a remarkably flexible and rich array of social competencies, demonstrating the ability to interpret, predict, and react appropriately to the behavior of others, as well as to engage others in a variety of complex social interactions. Developing computational systems that have similar social abilities is a critical step in designing robots, animated characters, and other computer agents that appear intelligent and capable in their interactions with (...) humans and each other. Further, it will improve their ability to cooperate with people as capable partners, learn from natural instruction, and provide intuitive and engaging interactions for human partners. Thus, human−animal team analogs can be one means through which to foster veridical mental models of robots that provide a more accurate representation of their near-future capabilities. Some digital twins of human−animal teams currently exist but are often incomplete. Therefore, this article focuses on issues within and surrounding the current models of human−animal teams, previous research surrounding this connection, and the challenges when using such an analogy for human−autonomy teams. (shrink)

This article examines the ‘integrated conception of competence’ as conceived by Paul Hager and David Beckett and suggests that its characterization in terms intended to distance it from behaviouristic and reductionist notions of competence is not sufficient to differentiate it from other models. Taking up Hager and Beckett’s idea that competence must be inferred from behaviour, it is suggested that this indicates how the integrated conception is more properly distinguished by virtue of the method used rather than what it is (...) that is assessed. Drawing on the work of Wittgenstein and Donald Davidson, it is argued that it is possible to discern two logically distinct methodological approaches to competence assessment, allowing a clear distinction to be made between the integrated conception and the kind of approach which predominates in the UK’s framework of vocational qualifications. While the latter is shown to be rightly criticized for its deficiencies, in contrast the integrated conception is seen to suggest a methodological approach that is capable of acknowledging the full richness of occupational practice. (shrink)

Buddhism perspectives on death; criticism on the thoughts of Buil khyup On Chan, a political leader and Shyan Ukkattha, a famous Buddhist monk in Burma.

This paper notes the apparent ineffectiveness of the critical response to competence-based education and training (CBET) and suggests that this results from a failure to correctly isolate CBET's unique, identifying features. It is argued that the prevailing tendency to identify CBET with ‘competence’ is fundamentally mistaken and that the competence approach is more properly characterised in terms of its philosophically naïve methodological strategy. It is suggested that this strategy is based upon untenable assumptions relating to the semantic status of statements (...) of outcome and the epistemological and ontological constructs to which such statements are intended to correspond. (shrink)

Le monde naturel comme probleme philosophique, these d'habilitation de Jan Patocka, parut d'abord en 1936, en meme temps que la premiere partie de la Krisis. C'etait alors le premier ouvrage - et longtemps le seul - expressement consacre a la notion, a la description et aux analyses husserliennes de la Lebenswelt. Si le jeune Patocka y demeure fidele au transcendantalisme de son maitre, c'est en toute independance qu'il tente la restitution du monde dans lequel nous vivons - dans un dialogue (...) avec l'analytique existentiale de Heidegger, la cosmologie de Fink, la theorie de la forme et les inspirations du Cercle linguistique de Prague. Cette nouvelle traduction, comprenant l'autocritique approfondie que l'auteur a tenu a ajouter en 1970 a la seconde edition tcheque, permet au lecteur de suivre le developpement de ce theme clef dans la genese de sa conception originale de l'existence en tant que mouvement et le virage vers une phenomenologie asubjective. (shrink)

This paper identifies the key assumptions underpinning current arrangements in vocational education and training (VET) in the UK. These assumptions, and the idea of vocational capability they denote, are rejected in favour of a more coherent conception—a conception centred not on the traditional dichotomy of ‘knowing how-knowing that’ but on what I refer to as the ‘constitutive understandings’ from which both practical and theoretical capabilities can be seen to derive. It is argued that an account of vocational capability in these (...) terms suggests a far richer conception of vocational preparation than current arrangements are able to admit. (shrink)

In 1999 the UN instituted the Program of Action on a Culture of Peace, leading to the Declaration of the International Decade for the Promotion of a Culture of Peace and Non-Violence for the Children of the World 2001-2010. This represented a paradigm shift away from the prevailing conceptualization of peace as ‘the absence of war’ to one of ‘creating cultures of peace’, and indicated a significant opening for peace educators and the expansion of their mission and field in peace (...) research and scholarship. This book seeks to address several questions about the emergence, present state, and future of the field of peace education, and to ground the definition of the discipline in its origins – origins deeply set in informal grassroots movements of concerned citizens, faith-based communities, and professional organizations who work for peace, as well as those working in formal institutions. These origins are vital in imparting identity, and in nurturing the current growing collective consciousness that combines the academic discipline and the worldwide peace movement – a collective that can unify, fuel, and inspire dialogue among scholars, researchers, activists, educators, government leaders, and the myriad of individuals committed to creating cultures of peace throughout the world. This book was originally published as a special issue of the _Journal of Peace Education. _. (shrink)

We can be certain that the body does not survive death. Once the heart stops circulating blood, the brain is no longer nourished and begins to decay. On the basis of medical evidence it would seem that, within a quarter of an hour, the personality is irreparably destroyed and the individual ceases to exist. But now there is mounting scientific evidence for a life after death. In At the Hour of Death, veteran psychical researchers Karlis Osis, Ph.D and Erlendur Haraldsson, (...) Ph.D collated compelling evidence that suggests we, as conscious beings, do survive physical death. This book is the product of extensive interviews of over 1,000 doctors and nurses who have been present when cases of "post-mortem existence" have occurred. Extensive computer analyses of their observations have been made. The results are reported in this first truly scientific investigation of the experiences of the dying at the hour of death. What these doctors and nurses have witnessed cannot be explained away by medical, psychological, cultural, or other conditioning. Yet it may answer the fundamental question of human existence. "Finally, a book that probes death and dying with modern research techniques. Osis and Haraldsson present compelling evidence that the deathbed is the gateway to another existence. The visions of the dying appear to be not hallucinations but glimpses through the windows of eternity." -Alan Vaughan, editor of New Realities Magazine "A major contribution to the scientific study of the question of post-mortem existence. -Raymond A. Moody, M.D., author of Life After Life. (shrink)

In this important book, a distinguished legal scholar examines how the legal culture and institutions in Anglo-American countries affect the way in which evidence is gathered, sifted, and presented to the courts.

This book derives from a 1993 National Endowment for the Humanities Summer Institute on Knowledge, Teaching, and Wisdom. The Institute took place at the University of California, Berkeley, and was co-directed by Keith Lehrer and Nicholas D. Smith. The aims of the Institute were several: we sought to reintroduce wisdom as a topic of discussion among contemporary philosophers, to undertake an historical investigation of how and when and why it was that wisdom faded from philosophical view, and to ask how (...) contemporary epistemological theories might apply to the obviously related subjects of teaching and wisdom. In recruiting participants, Lehrer and Smith put the greatest emphasis on those with professional interests in epistemology and the history of philosophy, of the ancient Greeks especially ancient Greek philosophy (because in the writings all three subjects of the Institute were explicitly related and discussed). But in addition to these two groups, some effort was made also to include others, with academic specializations in a variety of fields other than epistemology and the history of philosophy, to ensure that a broad perspective could be achieved in our discussions. To an obvious extent, the papers in this book reflect the recruitment emphases and variety. They also testify to the extent that the Institute managed to bring life to our subjects, and to raise very old questions in a contemporary context. (shrink)

Comprehensive Hindi commentary on the Sāṅkhyakārikā, philosophical work of the Sankhya school in Hindu philosophy, by Īśvarakr̥ṣṇa.

Alzheimer’s disease (AD) may be situated within a cultural landscape produced, in part, by demographics and the marketing strategies of an aggressive biopharmaceutical industry. The simultaneously corporeal and visual domain of advertisements for anti-AD drugs generates dynamic images of gender and embodiment, and it also lends itself to feminist interventions engaging with the images and ideas circulating around aging, medicine and the body. In this article, we investigate advertisements targeting medical practitioners treating patients with AD. Working within a methodological framework (...) we identify as ‘feminist visual studies of technoscience’, we want to propel the discussion in the direction of a broader corpus of medical media. Through this limited exercise, we hope to make a scholarly contribution to the feminist community by critiquing some of the images emerging within popular/scientific media with regard to Alzheimer’s, a disease collectively imagined within an aging Western population. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:The Journal of Aesthetic Education 37.3 (2003) 112-118 [Access article in PDF] Hong Kong Art: Culture and Decolonization, by David Clarke. Durham, North Carolina: Duke University Press, 2002, 240 pp. Paper. The issue of identity is a "vicious" circle in relation to Hong Kong's return to China in 1997. The more one talks about it, the more it is to be talked about as if it is a phenomenon (...) at a very special moment. But isn't not talking about Hong Kong identity in a certain period of time also a "vicious" circle, in which the lack of noise invites further silence?David Clarke's Hong Kong Art is, in a sense, an initiation of Hong Kong art as a "vicious" circle. In this sense, a concrete affinity between a text and its subject matter is significantly established. This is one of the ideals, potentials, and powers of all books written for the sake of being read and having actual effect. In this respect, this "vicious" circle is not vicious in a negative sense. It is through such interactivities that a book establishes a positive link with its subject matter.Hong Kong Art investigates "a particular historical moment in which HongKong art came into its own" (p. 10) and dwells upon the "local-ness of recent Hong Kong art" (p. 8). Nevertheless, Clarke deliberately avoids introducing a chronological survey of "Hong Kong art history as a whole" (p. 10). His solid research draws on the colloquial meanings of Hong Kong art in connection with the dynamics among different languages (Cantonese, Mandarin, and English), local receptions of art as reflected in local media, as well as backgrounds of artists, artworks, and political and cultural developments, among others. All this is necessary for a book that examines theemergence of Hong Kong identity. This is the case especiallyas "[n]o adequate survey exists of Hong Kong art as a whole," albeit surveying Hong Kong art as a whole is not the book's objective. Clarke's meta-survey about surveys on Hong Kong art is given in an endnote, which I also quote here in a note for the reader's reference. "The present author's Art and Place: Essays on Art from a Hong KongPerspective (Hong Kong, 1996) attempts to give a picture of the Hong Kong art world in the period immediately prior to the one covered by this text, and includes [End Page 112] some discussion of art from earlier periods as well. Petra Hinterthür'sModern Art in Hong Kong (Hong Kong, 1985) attempts a brief survey, but is of course unable to throw light on more recent developments. A chronology of Hong Kong art development from 1922 to 1994 is given in Hong Kong Artists. Volume 1 (Hong Kong, 1995), pp. 21-32. A rather patchy and sometimes imprecise chronology of Hong Kong artistic events from 1967 to 1998 isgiven in Gao Minglu, ed., Inside Out: New Chinese Art (Berkeley, 1998), pp. 207-11. The latter chronology also covers political and other broader historical events of the period. A valuable resource (in Chinese) for research on the early period of Hong Kong art is provided by Edwin Lai and Jack Lee, 'A Chronology of Visual Arts Activities in Hong Kong, 1900-1930,' in Besides: A Journal of Art History and Criticism 1 (1997): 135-230" (p. 211).With regard to the book's "ideal" link with its subject matter, I will now discuss the book's actualization of what it sets out to examine. The inadequacy of surveys on Hong Kong art (whether or not as a whole) manifests the relative tranquility in acknowledging that Hong Kong art is distinct. In view of this, the book itself is an intervention that (further) actualizes what it talks about. This is the case particularly in light of its predecessors' "vicious" circle of "silence," let alone those simplifications reducing Hong Kong art to either a Westernized product or a Chinese branch.The "Introduction" of Hong Kong Art begins with a critique of Western art history practices such as Gardner's... (shrink)

We present a Revised Projectivity Calculus that extends the scope of inclusion and exclusion inferences derivable under the Projectivity Calculus developed by Icard :705–725, 2012). After pointing out the inadequacies of C, we introduce four opposition properties which have been studied by Chow Proceedings of the 18th Amsterdam Colloquium, Springer, Berlin, 2012; Beziau, Georgiorgakis New dimensions of the square of opposition, Philosophia Verlag GmbH, München, 2017) and are more appropriate for the study of exclusion reasoning. Together with the monotonicity properties, (...) the OPs will form the basis of RC instead of the additive/multiplicative properties used in C. We also prove some important results of the OPs and their relation with the MPs. We then introduce a set of projectivity signatures together with the associated operations and conditions for valid inferences, and develop RC by inheriting the key features of C. We then show that under RC, we can derive some inferences that are not derivable under C. We finally discuss some properties of RC and point to possible directions of further studies. (shrink)

Interest in a hydrogen economy has grown significantly in the past decade. However, the success of old technologies that are being re-engineered to work on hydrogen, as well as the creation of new hydrogenbased technologies, hinges upon public interest in and demand for such technologies. With increasing investments in the research and development of hydrogen technologies, there exists a need to monitor public attitudes toward hydrogen to ensure its success as an alternative energy carrier. To address this need, two surveys (...) were conducted. The results of the first survey give insights about how colored information influences the public acceptance of hydrogen, and the results of the second survey elucidate what trade-offs the public is willing to accept during the transition to a hydrogen economy. Furthermore, the research highlights how hydrogen knowledge and acceptance differ among age, education, and gender groups. (shrink)

An assessment of Michael Naas's Miracle and Machine, which is devoted to a careful reading of Derrida's essay "Faith and Knowledge". This article focuses on survival and its temporality.