Katerina Deligiorgi offers a contemporary defence of autonomy which is Kantian but engages closely with recent arguments about agency, morality, and practical reasoning.

_Interprets Kant's conception of enlightenment within the broader philosophical project of his critique of reason._.

The article deals with the issue of motherhood as a space for the other in terms of its being a space shared with the other on both the biological level and also in the metaphorical sense of the word, where motherhood means accepting the other into the wider space of the body of a family, of society, and of the whole universe. This opening up of one’s space for the other necessarily implies that the space diminishes. The article explores the (...) theme through the work of two writers, Mother Maria Skobtsova and Hélène Cixous, as both reflect in their lives the idea of motherhood as a space for the other. It puts their voices into conversation from their different discourses. Mother Maria speaks the language of theology and poetry, and the artistic language of icons; Hélène Cixous the language of literary criticism, psychoanalysis, and creative writing. (shrink)

The concept of time is an integral part of any religious and philosophical system. It creates a universal cognitive strategy: seeing the world in its change and development, finding temporary relationships and order in everything. In Iranian mythology, where the cult of time was highly developed, time was personified by the higher deity Zurvan, who initially was imagined as an endless time, eternity, existing at the beginning of the universe, and then, in the latter part of the "Avesta" takes an (...) image of the final, natural, world time, who forecasts not only its beginning, but the end, death. Zurvan Akarana in Zoroastrianism - is unlimited Time or Eternity; one of the two primary forces that are mentioned in "Avesta" and "Yasna". Zurvan - is the Сreator who did not make a creation. He is only the foundation, the idea that gives impulse, like an explosion. It is similar to the concept of "dharma" in the Indian tradition, the "Logos" of Heraclites, the law by which the universe exists. Helps to the time, the main essence of space is the duration, the matter has the opportunity to come into effect. Late Avesta makes a distinction between endless time and time, which has a long duration, but finite. Later theologians interpreted endless time as eternity of being, and a long time was regarded as the duration of the world, which was created and will have an end. These ideas can be correlated with ideas that later we can find in Christianity, that person has a freedom of choice, and even later - in Islam, that person's fate is determined in advance. But Zoroastrianism is talking about the same thing, the fate of this material world in which evil is present is determined in advance, but in the world of Ahura Mazda person has the right to choose and there will get whatever deserves. The unconditional departure from mythological beliefs is also the idea of the linearity of time that we meet in Zoroastrianism and which later gets its continuation in Christianity. But in Zoroastrianism time is endless, and therefore is reversible and linear, and therefore simultaneously is irreversible. (shrink)

In this paper the authors seek to contribute to a new ontology of an embodied, desiring subject through an exploration of their own subjectivities and of the ways in which subjectivities are produced and transformed through affective attachments to place. Using the method of collective biography (Davies, Gannon 2006) and drawing on Deleuze and Guattari’s concepts of desire and territorialization they examine their affective responses and attachments to place: Australia and the Czech Republic. As a point of departure for their (...) analysis, the authors ask: What does it mean to be homesick for a place which is not one’s home? What does it mean to desire a place? What of the other place is inscribed in the body? In asking this, the authors show the extent to which place is a zone of immanence in which a continual play of de- and re-territorialization occurs. (shrink)

Purpose – Tabletop online role-playing games enable active learning appropriate for different ages and learner capabilities. They have also been implemented in computer and engineering ethics courses. The paper aims to discuss these issues. Design/methodology/approach – This paper presents the experience of implementing role-playing in several courses embedded in Web 2.0 environment, with an intention to confront complex and sometimes mutually conflicting concepts, and integrate them into a whole. Findings – Typical examples introducing two basic scenarios representing individual and collaborative (...) learning scripts are presented together with the detailed analysis how the games were performed, the effort to participate in, and to maintain them. Particular attention is paid to student feedback. Originality/value – The paper concludes with the basic findings of the effects of role-playing in current learning computer ethics and social responsibilities courses, and recommendations for future implementation of similar asynchronous learning online activities in order to increase their academic value and prepare students for their forthcoming professional integration. (shrink)

Alternative set theory was created by the Czech mathematician Petr Vopěnka in 1979 as an alternative to Cantor’s set theory. Vopěnka criticised Cantor’s approach for its loss of correspondence with the real world. Alternative set theory can be partially axiomatised and regarded as a nonstandard theory of natural numbers. However, its intention is much wider. It attempts to retain a correspondence between mathematical notions and phenomena of the natural world. Through infinity, Vopěnka grasps the phenomena of vagueness. Infinite sets are (...) defined as sets containing proper semisets, i.e. vague parts of sets limited by the horizon. The new interpretation extends the field of applicability of mathematics and simultaneously indicates its limits. Compared to strict finitism and other attempts at a reduction of the infinite to the finite Vopěnka’s theory reverses the process: he models the finite in the infinite. (shrink)

Hutto and Satne, Philosophia propose to redefine the problem of naturalizing semantic content as searching for the origin of content instead of attempting to reduce it to some natural phenomenon. The search is to proceed within the framework of Relaxed Naturalism and under the banner of teleosemiotics which places Ur-intentionality at the source of content. We support the proposed redefinition of the problem but object to the proposed solution. In particular, we call for adherence to Strict Naturalism and replace teleosemiotics (...) with autopoietic theory of living beings. Our argument for these adjustments stems from our analysis of the flagship properties of Ur-intentionality: specificity and directedness. We attempt to show that the first property is not unique to living systems and therefore poses a problem of where to place a demarcation line for the origin of content. We then argue that the second property is a feature ascribed to living systems, not their intrinsic part and therefore does not form a good foundation for the game of naturalizing content. In conclusion we suggest that autopoietic theory can not only provide a competitive explanation of the basic responding of pre-contentful organisms but also clarify why Ur-intentionality is attributed to them in such an intuitive manner. (shrink)

The book explores the themes of a) “radical concepts” in politics (inspired by François Laruelle’s “non-Marxism” and “non-philosophy,” developed in accordance with Badiouan and Žižekian “realism”); b) politically relevant and applicable epistemologies of “Thought’s Correlating with the Real” (Laruelle), inspired by Laruelle, Badiou and Žižek and c) the possibility of hybridization of the epistemic stance of “radical concept” with the politics of grief and “identification with the suffering itself” proposed by Judith Butler. Radical concepts, the political vision and the theory (...) based on them, are always already succumbing to the “Lived” (Laruelle), to the singularity of the Event (Badiou), to the encounter with the “kernel of the Real” (Žižek) conditioning a political horizon and the grand and small political narratives taking place within it. The thesis of the book is that the instances of the “lived,” the “event” or the “Real” can be inherently inter-connected by virtue of the category of the “experience” which is an instance of the sheer lived, the bare being subjected to an occurrence which is always already an instance of trauma. The mere subjection to certain” taking place,” the passion (in the etymological sense derived from the Latin verb pati or in the Spinozian sense) which is category beyond the psychological notions of feeling, rational (or irrational) thought, i.e., an ontological category referring to our relation with the “Out-There” which always already happens to us, is that to which the radical (political) concept succumbs to as the ultimate authority rather than to a doctrine, a system of thought, to the “philosophy’s auto-mirroring” (Laruelle). Political revolt or the revolutionary stance stems from precisely this bare experiential, the sheer lived and thus, from the Real of the conatus of staying-in-life. Paradoxically the survivalist stance, the principle of self-preservation is also the revolutionary stance which is by definition destabilizing and destructive. Bodily resistance to subjection (i.e., to discipline) and the continuity of the Self in-the-Real is the source of resistance. The Real of grief and mourning, the identification with the purely experiential stance of the suffering itself is the foundation of a “radical concept” of political solidarity, which by virtue of its being grounded in the Real, i.e., in the Lived, provides the possibility of acting in a revolutionary way. But it is also a form of human universality or political universality, which yet again is not historic universality but rather purely categorical. Other concepts that can be called radical, concepts which are minimally transcendental (Laruelle) and are, therefore, of revolutionary potential are also violence, mourning, labor (work) and gender (the trauma introduced by the linguistic determination as a “he” or a “she”), life, death, animal. Yet, the main focus of the book is the exploration of the lived of vulnerability, trauma and the conatus of life as the determination in the last instance of the revolutionary (political) stance. Clearly, the revolutions and the revolutionary stance this book advocates, or rather, whose potentiality it explores, are not necessarily historical revolutions produced by the intentionality to create politico-historic change. They are not this necessarily. Yet again they are such possibly. Still all purely (on the formal level) revolutionary stance tends to introduce universal change, radically change the political horizon and to reverse the politically unthinkable into a thinkable by elevating it to the level of a universal political truth. (shrink)

Thought experiments being central to contemporary philosophy and science, the following questions were asked in recent literature. What is their definition? Are they heuristic devices, arguments, paradoxes? Are they comparable to real experiments? Do intuition and conceivability intervene? Equally imaginative thought experiments are found in ancient, medieval, and Renaissance texts. Paying attention to prime historical examples of thought experiments, we show that historical perspectives help answer these general questions.

The paper explores the relationships and distinctions between pictorial and linguistic symbolic systems. It addresses the issue of the interplay between these media and symbolic systems. The paper explains why we cannot speak of any “pure” approaches and why it is necessary to be familiar with these mixed strategies. The central hypothesis is based on the idea of mutual "lending" of strategies and influences, leading to the emergence of a "new homogeneity," or a new semanticity and conceptualization. The main question (...) posed is: How does the linguistic symbolic system influence images, and how does the image symbolic system, in turn, influence language under contextual pressures? The first objective is to identify and analyze suitable examples of these pressures and “borrowings” to determine the domains of language and imagery. The analysis seeks to understand when these symbolic systems are most effective in their functions, when they exchange strategies, and what new meanings arise from this exchange. The second objective, derived from the first, is to defend the irreplaceability of the unique “message of the samples” (images) and how they symbolically create their version of the world in an irreplaceable way through words. Additionally, the paper aims to define a functional and irreplaceable space for words within the realm of visual art. (shrink)

This paper, located in the traditions of Interactional Sociolinguistics (Gumperz 1982) and Social Constructionism (Berger and Luckmann 1966), explores code-switching and identity practices amongst British-born Greek-Cypriots. The speakers, members of a Greek-Cypriot youth organization, are fluent in English and (with varying levels of fluency) speak the Greek-Cypriot Dialect. Qualitative analyses of recordings of natural speech during youth community meetings and a social event show how a new ‘third space’ becomes reified through code-switching practices. By skillfully manipulating languages and styles, speakers (...) draw on Greek-Cypriot cultural resources to accomplish two inter-related things. First, by displaying knowledge of familiar Greek-Cypriot cultural frames, they establish themselves as different from mainstream British society and establish solidarity as an in-group. Secondly, by using these frames in non-serious contexts, and at times mocking cultural attitudes and stereotypes, they challenge and re-appropriate their inherited Greek-Cypriot identity, thereby constructing the identity of British-born Greek-Cypriot youth. (shrink)

Laruelle's version of Marxism is termed "non-Marxism" whereby the "non-" is stated to stand for bracketing out Marxism's "philosophical sufficiency" and seeking to radicalise Marxism. It stands for the Laruellian non-philosophical variant of Marxism. It is precisely the non-philosophical use of Marx that has enabled the analysis at hand, demonstrating that at the heart of patriarchy and capitalism stands philosophical reason and its treatment of the Animal (both human and non-human). Women are de-realised even as use value and what is (...) exchanged in patriarchy is abstraction or the commodified femininity, which serves the multiplication of the surplus value or rather the pure value of masculinity. Just as the “C” in the M-C-M formula can be expunged as it is a mere relay for the endless repetition of the M-M automaton, so, to paraphrase Marx, because not an atom of matter enters the composition of woman as commodity, the material woman can be excluded from the equation P(hallus)-P(hallus). The less physicality in the pure value of femininity the more perfect the finite automaton of patriarchy. The fetishised femininity, as any form of commodity, is reified abstraction. The token of femininity is exchanged only in order for masculinity to engender itself. Masculinity (or the pure value of the Phallus), speculative reason, and rationalism are endowed with the same contempt for the physical, narcissistic circularity of thought and disgust for the woman outside the signifying automaton of fetishisation. (shrink)

Cognitive and emotional processes are now known to be intertwined and thus the limbic system that underlies emotions is important for human brain evolution, including the evolution of circuits supporting language. The neural substrates of limbic functions, like motivation, attention, inhibition, evaluation, detection of emotional stimuli and others have changed over time. Even though no new, added structures are present in the human brain compared to nonhuman primates, evolution tweaks existing structural systems with possible functional implications. Empirical comparative neuroanatomical evidence (...) is presented here in support of such changes in the limbic system, including the amygdala and the orbitofrontal cortex. Given their possible functional significance, these alterations may further enable and enhance human interest and motivation to communicate beyond what is seen in other primates living in complex social groups. The argument here is that even though emotion processing is likely needed for increased social complexity independent of language, the reason why humans want to talk may be related in part to the enhancement of socioemotional processes resulting from the reorganization and rewiring of underlying neural systems some of which are interconnected to the language areas. Neurodevelopmental disorders in humans affecting both language and sociability fuel such arguments. (shrink)

Physics is the most fundamental of the sciences and its main purpose is to explain how the world works on the smallest as well as the largest scales. This book outlines the most important discoveries and technical development in the field of physics during the past two decades. The reader will learn the basics of the major theories that form the backbone of the current understanding of the universe through descriptions of the latest findings in particle physics, quantum optics, structure (...) of matter or astrophysics. The book also explains how devices such as lasers or particle accelerators work. (shrink)

The opposition between the climactic thought of René Descartes and that of Blaise Pascal, although not very explicitly expressed at the time, is considered to be some kind of dispute between “reason and the heart.” An attempt at the relativization of these compartmentalizing poles brings the author of the study to a starting point that is common to Descartes’ Meditations on First Philosophy and Pascal’s Pensées (Thoughts): the act of skepticism and radical doubt. Despite the differences in their skeptical pathways (...) and their goals, the roots of the “systems” of thought of both philosophers grow from this act. The paper attempts to outline how the role of doubt can shape the problem of human knowledge, both on a general level and on the level of the highest, concrete knowledge of Divine Existence. (shrink)

This paper examines the concept of hope in the epistemology and psychology of Immanuel Kant and Johann Christoph Hoffbauer (1766-1827). The decisive question is how according to Kant hope can impair the objectivity of judgements about future and what are the positive and negative effects of this impairment. While for Kant hope is not essentially considered as an affect, he admits that it could transform into an affect and in this way it can impair the mood and its cognitive faculties (...) negatively. In my paper I examine this argumentations of Kant and their reception in the psychology and psychopathology of Hoffbauer, where hope as affect is even considered as a cause of madness and where Hoffbauer seems to suggest that the clinical state of madness can be effect of inappropriate use of the cognitive faculties of the soul. (shrink)

Ethnic diversity and cultural heterogeneity are a reality for the city of Skopje, the capital of North Macedonia. The changing ethnic demography and redressed power-balance between majority and non-majority groups on local level have spurred a turbulent conflict – that of governance of diversity in public space. This paper aims to understand citizens’ views on how language, ethnicity, religion and collective cultural symbols are legitimised through the political, social and symbolic value of public spaces in their neighbourhoods. The results indicate (...) that the political value of public spaces to stimulate contact, deliberation and debate among citizens on issues of their concern is undermined. Public spaces in Skopje are not planned and managed through a wide forum of citizen engagement. The colliding ethnonationalism and symbolic power struggle between the major ethnic groups result in co-ethnic preferences in socialisation and selection of public spaces. The concept of “the appropriate citizen” constructed through the symbolic meaning of public spaces perpetuates ethnonational rhetoric and supports expressions of citizenship that are limited to the nation-state and ethnic identification. In opposition to contact theory, this research indicates that self-segregation of ethnic groups can be prevalent in multi-ethnic neighbourhoods. This should make us think of the context where the contact is established and not only of the content of the interaction. (shrink)

The concept of professionalism is embedded into all aspects of nursing education and practice yet is rarely critically interrogated in nursing scholarship. This paper describes how professionalism in nursing is based on whiteness. When actualized, this oppressive construct homogenizes individuals' identities to assist nurses in building and wielding power against each other and against patients, and results in dehumanization and disconnection. Foregrounding an ethic of authenticity as a practice of resistance against white professionalism offers an alternative possibility for how nursing (...) could be taught, practiced and theorized. As such a practice must begin with oneself, the authors outline a reflexive process from which to begin this work. (shrink)

Departing from the premise that the poststructuralist paradigm still reigns supreme in feminist and gender theory, that is, despite the niche efforts made in the past two decades to challenge it linked to the so called “speculative” turn or the materialisms (and realisms) emerging from the feminist field itself (such as the Utrecht School, inspired by Rosi Braidotti), we set the call for papers for the issue before you in terms that would invite authors ready to challenge the dominant epistemic (...) framework. We invited papers that engage with materialism(s), realism(s), sciences and projects engaged in rethinking the post-human beyond the poststructuralist (and, we dare say, postmodern/ist) norm. -/- . (shrink)

Phenotypic plasticity is a crucial feature of aggressive cancer, providing the means for cancer progression. Stochastic changes in tumor cell transcriptional programs increase the chances of survival under any condition. I hypothesize that unstable chromatin permits stochastic transitions between transcriptional programs in aggressive cancers and supports non‐genetic heterogeneity of tumor cells as a basis for their adaptability. I present a mechanistic model for unstable chromatin which includes destabilized nucleosomes, mobile chromatin fibers and random enhancer‐promoter contacts, resulting in stochastic transcription. I (...) suggest potential markers for “unsettled” chromatin in tumors associated with poor prognosis. Although many of the characteristics of unstable chromatin have been described, they were mostly used to explain changes in the transcription of individual genes. I discuss approaches to evaluate the role of unstable chromatin in non‐genetic tumor cell heterogeneity and suggest using the degree of chromatin instability and transcriptional noise in tumor cells to predict cancer aggressiveness. (shrink)

In this essay, I propose that DNA‐binding anti‐cancer drugs work more via chromatin disruption than DNA damage. Success of long‐awaited drugs targeting cancer‐specific drivers is limited by the heterogeneity of tumors. Therefore, chemotherapy acting via universal targets (e.g., DNA) is still the mainstream treatment for cancer. Nevertheless, the problem with targeting DNA is insufficient efficacy due to high toxicity. I propose that this problem stems from the presumption that DNA damage is critical for the anti‐cancer activity of these drugs. DNA (...) in cells exists as chromatin, and many DNA‐targeting drugs alter chromatin structure by destabilizing nucleosomes and inducing histone eviction from chromatin. This effect has been largely ignored because DNA damage is seen as the major reason for anti‐cancer activity. I discuss how DNA‐binding molecules destabilize chromatin, why this effect is more toxic to tumoral than normal cells, and why cells die as a result of chromatin destabilization. (shrink)

Interpretations of Hegel’s social and political thought tend to present Hegel as critic of modern individualism and defender of institutionalism or proto-communitarianism. Yet Hegel has praise for the historically emancipatory role of individualism and gives a positive role to individuals in his discussion of ethics and the state. Drawing on Hegel’s analysis of the category of ‘individual’ in his Logic, this chapter shows that Hegel criticizes the conception of ‘individual’ as a simple and argues instead that it is a term (...) in need of specification or completion. Hegel’s revisionary logic of the category of ‘individual’ is both interesting in itself and useful as an interpretative tool, because it shows the consistency of his various statements about individuals in his practical philosophy. (shrink)

Byzantine philosophy is an almost unexplored field. Being regarded either as mere scholars or as primarily religious thinkers, Byzantine philosophers have not been studied on their own philosophical merit. The eleven contributions in this volume, which cover most periods of Byzantine culture from the 4th to the 15th century, for the first time systematically investigate the attitude the Byzantines took towards the views of ancient philosophers, to uncover the distinctive character of Byzantine thought.

Our philosophical moral vocabulary expresses a predilection for depth; we customarily probe feelings, intentions, reasons for action. Friedrich Schiller's concept of grace offers an alternative: moral guidance is best sought in what we train ourselves to set aside, facial expression, sound of voice, movement. This surprising proposal merits our attention and speaks to some of our current concerns.

While the emancipatory efforts of the Czech national revival culminated at the end of the 18th and in the 19th century, manifestations of national feeling in the 17th century Czech Lands were rather rare. The article focuses on the concept of nationality as it was treated by scholars from the monastic orders such as the German provincial of the Czech Franciscan province, Bernhard Sannig (1637–1704), or the Czech Jesuit Bohuslav Balbín (1621–1688), whose views are briefly compared with those of the (...) most significant representative of the Czech Protestant emigration – Johann Amos Comenius (1592–1670). By the means of analysis and comparison of several texts, the article investigates how the concept of nationality was gradually rationalized and moralized through the ethical categories of vice and virtue. These reflections on nation, nationality, and patriotism and their moral assessment demonstrate that their authors anticipated some elements of the later formulated doctrine of the natural law of nations, which theoretically justified the demands of the Czech national revival and formed the basis for the concept of Czech history. (shrink)

The article presents the German philosopher G. W. Leibniz as a key precursor of the First Law of Thermodynamics. In this way, Leibniz tried to oppose Newton, who seems to have completely rejected the First Law of Thermodynamics, while at the same time remarkably anticipating the Second. Based on his polemics not only with Newton, from whose Laws of Motion thermodynamics originates, and with his advocate Samuel Clarke, but also with René Descartes, whose conception Leibniz partially followed, Leibnizʼs reasoning turns (...) out to be the most convincing. It is certainly no coincidence that the later founders of thermodynamics frequently acknowledged him. (shrink)

Hegelian ethics, which gives pride of place to the roles and relations that give substance to our moral life, is seen as a rejection of Kant's a priori treatment of morality, moral law and moral agency. Analysis of the so-called religious writings from the late 1790s to the early 1800s, 'The Positivity of the Christian Religion', the 'Love' fragment, and the essay 'On the Scientific Treatment of Natural Law', shows Hegel engaging profoundly with recognizably Kantian problems of moral metaphysics about (...) moral agency, the moral law, nature and freedom. The almost experimental approach of these early pieces yields independently interesting results as well as offering an important insight into the development of Hegel's thought. (shrink)