In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Divine Illumination: The History and Future of Augustine’s Theory of KnowledgeSteven P. MarroneLydia Schumacher. Divine Illumination: The History and Future of Augustine’s Theory of Knowledge. Challenges in Contemporary Theology. Chichester: Wiley-Blackwell, 2011. Pp. xiii + 250. Cloth, $119.95.Lydia Schumacher has written an ambitious book. Among the many things she tries to accomplish in the volume, three stand out to this reviewer. First of all, she proposes (...) to reexamine Augustine’s theory of knowledge. She argues that Augustine’s philosophy is grounded in theology. For his theory of knowledge this means, by Schumacher’s reading, that the aim of cognition is to enable the human being to regain its original status as “image of God,” which latter state is manifested in knowing God and making God known. It is the mental, and by extension ethical, process of becoming God’s image that Schumacher says we should, in the Augustinian context, take the phrase ‘divine illumination’ to signify. For Augustine, Schumacher insists, this process is an entirely internal phenomenon constituted by a self-correcting series of intellectual reflections on the part of the mind. In holding to this view, Schumacher emphatically rejects the understanding, common in scholarship, that “divine illumination” for Augustine had to do with mental reference to what she labels an “extrinsic” standard such as the eternal ideas in God’s mind. [End Page 293]Second, Schumacher argues that the Augustinian project, epitomized in his theory of knowledge, was carried out by most of the thinkers of the Latin Middle Ages, particularly by Anselm and Thomas Aquinas. These latter two individuals are therefore divine illumi-nationists of the first order. What historians often designate as an Augustinian current, evident in the high Middle Ages among scholastics from the Franciscan Order, represented instead a deviation, a turn to an entirely novel theological-philosophical project. Here, mind’s work was conceived of as “the immediate and totalized knowledge of an individual essence.” And for this, recourse to an extrinsic standard filled the bill. Consequently, high-medieval Franciscans were the actual propounders of the theory of knowledge Schumacher tells us has wrongly been associated with divine illumination. Moreover, this Franciscan current of thought, once severed from its original theological underpinnings, provided the historical inspiration for modern philosophy, thereby acting as a kind of catalyst for the modernist philosophical problems—as Schumacher receives them—of rationalism and fideism, skepticism as well.Third, Schumacher sounds the call for a contemporary return to the authentic Augustinian project. By starting philosophy, as she claims Augustine did, with theological assumptions, she wants to fashion a “faith-based concept of knowledge” and with it, most importantly, to escape the modernist dilemma of the incompatibility of faith and reason. Grounding philosophy in theology—Christian theology, she maintains—will restore a lost integrity to our procedures of thinking, ultimately redeeming philosophy itself.How much of this program has Schumacher managed to achieve? Since this reviewer is marked out as the key spokesperson for the interpretation of both divine illumination and the history of medieval thought against which Schumacher inveighs, perhaps he should not be the one to answer the question. Still, the reader forewarned, I lay out my opinion. With regard to her first goal, Schumacher makes good on her promise to render Augustine as a theologian bent on working from his assumptions to designate a process whereby philosophy and mankind can be simultaneously restored. She is not so convincing in her attempt to equate this program with divine illumination. For Schumacher, the process of divine illumination is correlative to the idea of God as source of the mind’s power to act. Yet Augustine often plainly associates what he describes as illumination with turning to God and conceding his ideas an important role in the mental processes of judgment and concept formation. It is hard to see how one can honestly exclude this extrinsic element of what Augustine intended.Regarding her second goal, Schumacher does an excellent job of reminding us how Augustinian were almost all medieval scholastics, Thomas included, and warning us not to take the high-scholastic recourse to Aristotle as a sign of opposition to Augustinian modes of thought... (shrink)

Numerous studies suggest that both emotion knowledge and language abilities are powerfully related to young children’s theory of mind. Nonetheless, the magnitude and direction of the associations between language, emotion knowledge, and theory-of-mind performance in the first years of life are still debated. Hence, the aim of this study was to assess the direct effects of emotion knowledge and language on theory-of-mind scores in 2- and 3-year-old children. A sample of 139 children, aged between 24 and 47 (...) months ( M = 35.5 months; SD = 6.73), were directly administered measures of emotion knowledge, theory of mind, and language. We conducted structural equation modeling (SEM) to evaluate the effects of these variables within a single comprehensive framework, while also controlling for any effects of age and gender. The proposed structural equation model provided an excellent fit for the data, indicating that both children’s emotion knowledge, and their language ability had direct positive effects on theory of mind scores. In addition, age was found to wield statistically significant effects on all the variables under study, whereas gender was not significantly associated with any of them. These findings suggest the importance of fostering young children’s emotion knowledge and language ability with a view to enhancing their comprehension of mental states. (shrink)

Cumulative technological culture can be defined as the progressive diversification, complexification, and enhancement of technological traits through generations. An outstanding issue is to specify the cognitive bases of this phenomenon. Based on the literature, we identified four potential cognitive factors: namely, theory-of-mind, technical-reasoning, creativity, and fluid-cognitive skills. The goal of the present study was to test which of these factors—or a combination thereof—best predicted the cumulative performance in two experimental, micro-society conditions differing in the nature of the interaction allowed (...) between participants. The task was to build the highest possible tower. Participants were also assessed on the four aforementioned cognitive factors in order to predict cumulative performance and attractiveness. Our findings indicate that technical-reasoning skills are the best predictor of cumulative performance, even if their role may be restricted to the specific technological domain. Theory-of-mind skills may have a facilitator role, particularly in the Communication condition. Creativity can also help in the generation of novel ideas, but it is not sufficient to support innovation. Finally, fluid cognition is not involved in cumulative technological culture. Taken together, these findings suggest that domain-specific knowledge remains critical for explaining cumulative technological culture. (shrink)

Recent proponents of the ‘theory theory’ of mind often trace its roots back to Wilfrid Sellars’ famous ‘myth of Jones’ in his 1956 article, ‘Empiricism and the Philosophy of Mind’. Sellars developed an account of the intersubjective basis of our knowledge of the inner mental states of both self and others, an account which included the claim that such knowledge is in some sense theoretical knowledge. This paper examines the nature of this claim in Sellars’ original account and (...) its relationship to more recent debates concerning ‘theory of mind’, in particular the theory theory. A close look reveals that Sellars’ original view embodied several distinctions that would enable more recent theory theorists to accommodate certain phenomenological objections that have been raised against that outlook. At the heart of the philosophical issue is an overlooked complexity involved in Sellars’ account of the ‘theory/observation’ distinction, involving a conception of the distinction that is both independently plausible and a key to the issue in dispute. (shrink)

Nichols offers the first comprehensive interpretation of the eighteenth-century Scottish philosopher Thomas Reid's theory of perception - by far the most important feature of his philosophical system. Nichols's consummate knowledge of Reid's texts, lively examples, and plainspoken style make this book especially readable. It will be the definitive analysis for a long time to come.

In recent decades, the scientific study of consciousness has significantly increased our understanding of this elusive phenomenon. Yet, despite critical development in our understanding of the functional side of consciousness, we still lack a fundamental theory regarding its phenomenal aspect. There is an “explanatory gap” between our scientific knowledge of functional consciousness and its “subjective,” phenomenal aspects, referred to as the “hard problem” of consciousness. The phenomenal aspect of consciousness is the first-person answer to “what it’s like” question, and (...) it has thus far proved recalcitrant to direct scientific investigation. Naturalistic dualists argue that it is composed of a primitive, private, non-reductive element of reality that is independent from the functional and physical aspects of consciousness. Illusionists, on the other hand, argue that it is merely a cognitive illusion, and that all that exists are ultimately physical, non-phenomenal properties. We contend that both the dualist and illusionist positions are flawed because they tacitly assume consciousness to be an absolute property that doesn’t depend on the observer. We develop a conceptual and a mathematical argument for a relativistic theory of consciousness in which a system either has or doesn’t have phenomenal consciousness with respect to some observer. Phenomenal consciousness is neither private nor delusional, just relativistic. In the frame of reference of the cognitive system, it will be observable and in other frame of reference it will not. These two cognitive frames of reference are both correct, just as in the case of an observer that claims to be at rest while another will claim that the observer has constant velocity. Given that consciousness is a relativistic phenomenon, neither observer position can be privileged, as they both describe the same underlying reality. Based on relativistic phenomena in physics we developed a mathematical formalization for consciousness which bridges the explanatory gap and dissolves the hard problem. Given that the first-person cognitive frame of reference also offers legitimate observations on consciousness, we conclude by arguing that philosophers can usefully contribute to the science of consciousness by collaborating with neuroscientists to explore the neural basis of phenomenal structures. (shrink)

Autonomous Knowledge: Radical Enhancement, Autonomy, and the Future of Knowing motivates and develops a new research programme in epistemology that is centred around the concept of epistemic autonomy.

Theories of Information, Communication and Knowledge.

The stated subject of these lecture courses given by Husserlbetween 1910 and 1918is ‘reason, the word for the mental activities and accomplishments that govern knowledge, give it form and supply it with norms.’ They show their author still pursuing the course set out in the Logical Investigations up to the end of the second decade of the century and displaying utter consistency with stands that he began taking on meaning, analyticity, Platonism, manifolds, mathematics, psychologism, etc. in the 1890s. Thus, they (...) undermine many idées reçues about the development of his thought. The centerpiece of this work is an exploration of the realm of meaning. Moreover, they add new dimensions to standard discussions by taking readers back to the place where phenomenology and analytic philosophy diverged. They show that Husserl tangled long and hard with the very ideas that went into the making of the latter and offer a wealth of interesting insights into sense and meaning, theory of judgment, complete and incomplete meanings, states of affairs, extensional logic, the relationship between logic and mathematics, functions and arguments, propositional functions, quantification, existential generalization, the word ‘all,’ number theory, sets, modality, deductive theory, ideas that are still under discussion today. Prepared for oral delivery in the classroom, they are refreshingly lively and spontaneous. They are clearer, more explicit, and readable than the books Husserl published during his lifetime. (shrink)

Theory of Mind (ToM) is the cognitive achievement that enables us to report our propositional attitudes, to attribute such attitudes to others, and to use such postulated or observed mental states in the prediction and explanation of behavior. Most normally developing children acquire ToM between the ages of 3 and 5 years, but serious delays beyond this chronological and mental age have been observed in children with autism, as well as in those with severe sensory impairments. We examine data (...) from studies of ToM in normally developing children and those with deafness, blindness, autism and Williams syndrome, as well as data from lower primates, in a search for answers to key theoretical questions concerning the origins, nature and representation of knowledge about the mind. In answer to these, we offer a framework according to which ToM is jointly dependent upon language and social experience, and is produced by a conjunction of language acquisition with children's growing social understanding, acquired through conversation and interaction with others. We argue that adequate language and adequate social skills are jointly causally sufficient, and individually causally necessary, for producing ToM. Thus our account supports a social developmental theory of the genesis of human cognition, inspired by the work of Sellars and Vygotsky. How are we to decide whether to take reason to be an essentially private thing that can, however, turn on a public display when it chooses to do so, or, like conversing, to be an essentially social skill, which can, however, be retained a while through periods of solitary confinement? (Annette Baier, The Commons of the Mind, p. 5). The squirrel does not infer by induction that it is going to need stores next winter as well (Wittgenstein, On Certainty§ 287). The problem of thought and language thus extends beyond the limits of natural science and becomes the focal problem of historical human psychology, i.e. of social psychology. Consequently, it must be posed in a different way (Vygotsky, Thought and Language, p. 51). From the very first days of the child's development his activities acquire a meaning of their own in a system of social behaviour and, being directed towards a definite purpose, are refracted through the prism of the child's environment. The path from object to child and from child to object passes through another person. This complex human structure is the product of a developmental process deeply rooted in the links between individual and social history (Vygotsky, Mind in Society, p. 30). (shrink)

This is a very selective survey of developments in epistemology, concentrating on work from the past twenty years that is of interest to philosophers of science. The selection is organized around interesting connections between distinct themes. I first connect issues about skepticism to issues about the reliability of belief-acquiring processes. Next I connect discussions of the defeasibility of reasons for belief to accounts of the theory-independence of evidence. Then I connect doubts about Bayesian epistemology to issues about the content (...) of perception. The last detailed connection is between considerations of the finiteness of cognition and epistemic virtues. To connect the connections I end by briefly discussing the pressure that consideration of social roles in the transmission of belief puts on the purposes of epistemology. (shrink)

This dissertation does not argue for a particular theory of realism. It seeks to clear the ground for such a theory by clarifying the distinction between realism and reality. Realism is not reality. 'Realism' stands for theories that describe reality and how it exists mind-independently. I argue that much recent writing on realism misses the import of this distinction and proceeds "anti-philosophically." While some statements refer uncontroversially to an accepted state of affairs, others amplify, vouchsafe, or explain a (...) philosophical compunction about the received notion of reality. Philosophy consists, in accounting for what one does, says exists, or knows. So, the mere acceptance of the supposed "facts" is anti-philosophical. ;Philosophy should accept at least some "facts." But it has to rise above first order obviousness in order to dismiss or accept received views. The effort to proceed "antiphilosophically," insists that some statements or material be accepted uncritically or neutrally as explaining or settling important philosophical issues without philosophical assistance. ;Accordingly, I reject Devitt's "proposal" that we can "settle the realism issue before any epistemic or semantic issue" . Issues of reference cant help but pertain to settling that "Tokens of most current common-sense and scientific objects objectively exist independently of the mental" . The "constructivist turn" in realism holds that "realism" describes mind-independent entities, but not in a way that is itself independent of knowledge or meaning. Realism and much else, including our "facts," is "constructed" ; reality isn't. Hence, I also reject John Searle's attempt to "construct" all of social reality from non-social or "brute" reality alone. It is only by the social that we know the "non-social." I reject Michael Dummett's theory that the theory of meaning "underlies" metaphysics. Regardless, statements still refer to entities, without which they mean nothing. I favor Hilary Putnam's attempt to reject metaphysical realism despite his leanings toward idealism and a "limit concept" of reason and truth. Finally, I argue that Rorty's arguments for the "pointlessness" of realist and antirealist discussion are self-contradictory and nearly irrelevant. (shrink)

Originally published in 1949. Understanding the questions is the major problem when beginning philosophy. This book does not attempt to provide the answers, but defines the questions and shows by example how they should be tackled. Subjects treated include the nature of the objects of thought and judgment; truth and error in belief; perception and knowledge of the material world; the status and function of memory.

A comprehensive introduction to the theory of knowledge, this work explores what it is to be a rational, sentient human being.

General Theory of Knowledge is an exciting, acutely reasoned treatise, in which Schlick prepares the way for the modern analytic movement. Moritz Schlick is best known as the founder and guiding genius of the Vienna Circle of Logical Positivists.

This book contains the definitive statement of Franz Brentano's views on meta physics. It is made up of essays which were dictated by Brentano during the last ten years of his life, between 1907 and 1917. These dictations were assembled and edited by Alfred Kastil and first published by the Felix Meiner Verlag in 1933 under the title Kategorienlehre. Kastil added copious notes to Brentano's text. These notes have been included, with some slight omissions, in the present edition; the bibliographical (...) references have been brought up to date. Brentano's approach to philosophy is unfamiliar to many contemporay readers. I shall discuss below certain fundamental points which such readers are likely to find the most difficult. I believe that once these points are properly understood, then what Brentano has to say will be seen to be of first importance to philosophy. THE PRIMACY OF THE INTENTIONAL To understand Brentano's theory of being, one must realize that he appeals to what he calls inner perception for his paradigmatic uses of the word "is". For inner perception, according to Brentano, is the source of our knowledge of the nature of being, just as it is the source of our knowledge of the nature of truth and of the nature of good and evil. And what can be said about the being of things that are not apprehended in inner perception can be understood only by analogy with what we are able to say about ourselves as thinking subjects. (shrink)

I argue that having a theory of mind requires having at least implicit knowledge of the norms of the community, and that an implicit understanding of the normative is what drives the development of a theory of mind. This conclusion is defended by two arguments. First I argue that a theory of mind likely did not develop in order to predict behavior, because before individuals can use propositional attitudes to predict behavior, they have to be able to (...) use them in explanations of behavior. Rather, I suggest that the need to explain behavior in terms of reasons is the primary function of a theory of mind. I further argue that in order to be motivated to offer explanations of behavior, one must have at least an implicit understanding of appropriate behavior, which implies at least an implicit understanding of norms. The second argument looks at three cases of nonhuman animal societies that appear to operate within a system of norms. While there is no evidence that any species other than humans have a theory of mind, there is evidence that other species have sensitivity to the normative. Finally, I propose an explanation for the priority of norms over a theory of mind: given an understanding of norms in a society, and the ability to recognize and sanction violations, there developed a need to understand actions that violated the norms, and such explanations could only be given in terms of a person's reasons. There is a significant benefit to being able to explain behavior that violates norms, because explanations of the right sort can also serve to justify behavior. (shrink)

Theory of Thought and Knowledge is an unchanged, high-quality reprint of the original edition of 1897. Hansebooks is editor of the literature on different topic areas such as research and science, travel and expeditions, cooking and nutrition, medicine, and other genres. As a publisher we focus on the preservation of historical literature. Many works of historical writers and scientists are available today as antiques only. Hansebooks newly publishes these books and contributes to the preservation of literature which has become (...) rare and historical knowledge for the future. (shrink)

What is suspense and how is it created? An answer to this question constitutes a theory of suspense. I propose that any theory of suspense needs to be able to account for three curious features: (1) Suspense is seldom felt in our daily lives, but frequently felt in response to works of fiction and other narrative artworks. [Narrative Imbalance] (2) It is widely thought that suspense requires uncertainty, but we often feel suspense in response to narratives when we (...) have knowledge of the outcome. [Paradox of Suspense] (3) The amount of suspense felt in response to a narrative typically diminishes on repeated encounters. [Diminishing Returns] I offer a theory of suspense that can explain these three features. I argue for a theory called the Desire-Frustration Theory of Suspense, which holds that suspense results when our desire to effect the outcome of an imminent event is frustrated. (shrink)

This new edition of the classic Contemporary Theories of Knowledge has been significantly updated to include analyses of the recent literature in epistemology.

Excerpt from Vector Analysis and the Theory of Relativity One of the most striking effects of the publication of Einstein's papers on generalized relativity and of the discussions which arose in connection with the subsequent astronomical observations was to make students of physics renew their study of mathematics. At first they attempted to learn simply the technique, but soon there was a demand to understand more; real mathematical insight was sought. Unfortunately there were no books available, not even papers. (...) Dr. Murnaghan's little book is a most successful attempt to supply what is a definite need. Every physicist can read it with profit. He will learn the meaning of a vector for the first time. He will learn methods which are available for every field of mathematical physics. He will see which of the processes used by Einstein and others are strictly mathematical and which are physical. Every chapter is illuminating, and the treatment of the subject is that of a student of mathematics and is not developed ad hoc. The extension of surface and line integrals is most interesting for physicists and the discussion of the space relations in a four-dimensional geometry is one most needed. This is specially true concerning the case of point-symmetry which forms the basis of Einstein's formulae for gravitation as applied to the solar system. I feel personally that I owe to this book a great debt. I have read it with care and shall read it again. It has given me a definiteness of understanding which I never had before, and a vision of a field of knowledge which before was remote. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works. (shrink)

In part I of this paper I argue that on his theory of the mind as the idea of an actually existing body Spinoza is unable to account for the ability of the mind to have adequate knowledge, and I suggest that his theory of the eternity of the mind can be viewed as his solution to this problem. In part II I deal with the question of the meaning of ‘eternity’ in Spinoza, in regard both to God (...) and the human mind, and I sketch a line of thought which I believe may have provided him with further motivation for his theory that a part of the mind is eternal. (shrink)

Developed in collaboration with the International Baccalaureate Organization, Oxford's Course Companions provide extra support for students taking IB Diploma Programme courses. They present a whole-course approach with a wide range of resources, and encourage a deep understanding of each subject by making connections to wider issues and providing opportunites for critical thinking. This companion stimulates students to think about learning and knowledge from their own and from others' perspectives in a way that crosses disciplines and cultures. It encourages reflection, discussion, (...) critical thinking, and awareness or the ways in which knowledge is constructed, and will students to recognize the implications of knowledge for issues of global concern. Places students at the center of the course, with lively material providing opportunities for questioning, discussion, and interaction Invites students to add their own voices to those in the book, which include students, teachers, and professionals in various areas of knowledge Encourages students to frame their own perspectives with international awareness and recognition of the impact of knowledge on the world Contains guidance for current assessment, with support for the Theory of Knowledge essay and class presentation Written by experienced teachers, authors, and examiners, including recent deputy and chief examiners of Theory of Knowledge. (shrink)

“Virtue jurisprudence” is a normative and explanatory theory of law that utilises the resources of virtue ethics to answer the central questions of legal theory. The main focus of this essay is the development of a virtue–centred theory of judging. The exposition of the theory begins with exploration of defects in judicial character, such as corruption and incompetence. Next, an account of judicial virtue is introduced. This includes judicial wisdom, a form of phronesis, or sound practical (...) judgement. A virtue–centred account of justice is defended against the argument that theories of fairness are prior to theories of justice. The centrality of virtue as a character trait can be drawn out by analysing the virtue of justice into constituent elements. These include judicial impartiality (even–handed sympathy for those affected by adjudication) and judicial integrity (respect for the law and concern for its coherence). The essay argues that a virtue–centred theory accounts for the role that virtuous practical judgement plays in the application of rules to particular fact situations. Moreover, it contends that a virtue–centred theory of judging can best account for the phenomenon of lawful judicial disagreement. Finally, a virtue–centred approach best accounts for the practice of equity, departure from the rules based on the judge’s appreciation of the particular characteristics of individual fact situations. [ABSTRACT FROM AUTHOR]. (shrink)

This book confronts one of the central questions of political science: how people choose to accept or not to accept particular governments. In contrast to the prevailing view that citizens' decisions about the legitimacy of their governments are strongly conditioned by political culture and socialization and are hence largely non-rational, Ronald Rogowski argues that such decisions may indeed be the product of rational choice. The book proceeds both from recent work in the theory of voting and constitutional choice and (...) from the older tradition of contract theory to postulate that decisions about legitimacy are really choices among alternative regimes. The author suggests that members of a society choose among these alternative regimes on the basis of a knowledge of ethnic and occupational divisions in their society. From these postulates a general theory is derived, which finds expression in numerous testable hypotheses. Originally published in 1974. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905. (shrink)

Some sociological theories yield self-subverting or 'dangerous' knowledge. The functionalist theory of social deviance provides a case in point. The theory, first formulated by Durkheim, maintains that ostensibly anti-social deviants perform a number of socially indispensable functions. But what would happen if everyone knew this? They would cease to regard deviants as malefactors and would indeed come to esteem them as public benefactors. In that case, however, deviants could no longer perform their proper function. If they are to (...) play the part assigned to them by the theory, most people must remain unaware of their 'true' role in the drama of social life. This gives rise to the paradox of dangerous knowledge: The theory can be true only if its truths are not widely known; widespread ignorance is the precondition of its truth. But then, if its truths must not be publicly known, the theory is a piece of esoterica, not of science. I conclude by considering, and rejecting, several possible solutions to the 'dangerous knowledge' paradox. (shrink)

There is a widespread misinterpretation of kant according to which an analytic judgment is one that follows from a definition. Through a study of kant's theory of definition, And the role in knowledge that he ascribes to definition, It is shown that this is indeed a misinterpretation. Much criticism of kant's theory of analytic judgments is vitiated by substituting a modern definition of "analytic" for the one kant gave.

MacDonald and Kreitman (1991) propose a test of the neutral mutationrandom drift (NM-RD) hypothesis, the central claim of the neutral theory of molecular evolution. The test involves generating predictions from the NM-RD hypothesis about patterns of molecular substitutions. Alternative selection hypotheses predict that the data will deviate from the predictions of the NM-RD hypothesis in specifiable ways. To conduct the test Mac- Donald and Kreitman examine the evolutionary dynamics of the alcohol dehydrogenase (Adh) gene in three species of Drosophila. (...) The test compares the number of DNA sequence changes between species and within species. The number of DNA differences is an indicator of the evolutionary rate of the Adh gene. Based on the test they conclude that there is strong evidence for adaptive protein evolution at particular sites in the gene. Understanding the test requires some basic knowledge about molecular terms and the predictions of neutral theory. The two important terms are fixed differences and polymorphisms. These are determined by comparing DNA sequences made up of thousands of individual nucleotide sites. A site that is unchanged within a species but different from a related species counts as a fixed difference. These are mutations that occur in some common ancestor of the lineage such that all descendants inherit the change. A site that differs within a species counts as a polymorphism. Determining the number of fixed differences and polymorphisms requires placing 1 each individual gene sequence onto a phylogenetic tree. A coalescent tree charts the ancestral relationships for a set of individual gene sequences. Sequences sampled from within a species form a within-species tree. The common ancestors of each within-species tree form a between-species tree. A detected difference counts as a polymorphism or a fixed difference depending on where it occurs in the phylogenetic tree (cf. Table 1). The test uses the numbers of polymorphisms and fixed differences as indicators of evolutionary rates.. (shrink)

In the theoretical philosophy of Immanuel Kant, the term object has an extensive and far-reaching significance, and it can therefore be understood as a theory of objects. This becomes particularly clear when it is observed that all of his guidelines can be traced to different concepts of objects and their combination. With his concept of the object of experience, he attempts to mediate incompatible aspects in this: in relation to the object of experience, we have apodictic claims but at (...) the same time our knowledge of the object develops and contains the possibility of historical progress. This theory of objects was elaborated by Kant with regard to natural science and the claim of its metaphysical foundation. For this reason, Kant’s concept of object is inherently linked with his concept of science. Astronomy is at the core of his investigation, because it represents a perfect example of a so-called proper and rational natural science. (shrink)