The confounding effects of heterogeneity in biological psychiatry and psychiatric genetics have been widely discussed in the literature. We suggest an approach in which heterogeneity may be put to use in hypothesis testing, and may find application in evaluation of the Crespi & Badcock (C&B) imprinting hypothesis. Here we consider three potential sources of etiologic subtypes for analysis.

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Meaning and Interpretation: Wittgenstein, Henry James, and Literary KnowledgeWilliam FleschMeaning and Interpretation: Wittgenstein, Henry James, and Literary Knowledge, by G. L. Hagberg; xi & 178 pp. Ithaca: Cornell University Press, 1994, $27.50.The idea of studying Henry James and the later Ludwig Wittgenstein together is attractive, although there is very little stylistic similarity between them. Wittgenstein writes like a novelist, James like a philosopher. Wittgenstein is intensely interested (...) in the real language of real people; most of James’s dialogues bristle with a peculiarly Jamesian stiltedness. But both writers focus on the exquisite, extensive subtleties of language and of linguistic interaction, subtleties that tend to make uselessly crude such notional entities as facts, meanings, or ideas, and so of an epistemology based on such entities. The extremely fine grain of James’s analyses of his characters and of their analyses of each other already commits him philosophically to agreeing with Wittgenstein’s central insight that “to imagine a language means to imagine a form of life”: to James’s characters life consists in interpretation of each other’s language. Those characters have the deepest lives who come to the greatest subtlety in their investigations of what determines the deeply overdetermined linguistic moves made by other minds.Hagberg’s book is disappointing, however. The exposition of Wittgenstein is unexceptionable but hardly novel, and as for James, Hagberg has confined himself to four stories, considerable to be sure, but hardly the novels. Hagberg gives creditable readings of these stories, especially “The Lesson of the Master” and “The Figure in the Carpet.” But he treats James’s stories more as demonstrations of his philosophical point—that there is an analogy between language games and works of art, also an analogy between our attitude towards a person and our attitude towards a work of art—than as works of art themselves. This would be fine if he didn’t keep asserting that they are examples of what they address: perhaps they are, but Hagberg makes them out primarily as didactic. Thus in “Figure” he finds a clear and direct argument that one ought not look for some propositional content as the point or secret of a work of art and thus a fortiori of a story like the one under consideration. [End Page 373] Hagberg is right, of course, but he reduces the story to a moral in just the way he claims it warns us to avoid.In his treatment of “Lesson,” he writes with real insight about the ambiguities of the master’s motivation in that story, and argues convincingly that the motivation may be opaque to the master himself, but then retreats from the insight thus won by treating ambiguity itself rather literal-mindedly, as a sort of resultant of several unambiguous vectors. Although the comparison of ambiguity to seeing aspects is fascinating, Hagberg’s analysis would be inevitably enriched by treating The Golden Bowl, where Adam Verver remains essentially ambiguous. Hagberg’s readings falter because his sense of language-games is too flat: he doesn’t take into account (although he claims to) their genuine variety. For Hagberg, unlike for Wittgenstein, games always have well-defined moves, and so ambiguity becomes a move. But what if it’s ambiguous whether it’s a move or not?Perhaps Hagberg’s account of “The Tree of Knowledge” is least in the spirit of Wittgenstein. In Philosophical Investigations Wittgenstein writes, “I can know what someone else is thinking, not what I am thinking” (Part II, section xi). But Hagberg, in a taxonomy of kinds of knowing, takes it for granted that I can know what I am thinking (pp. 153, 169): again, this is a way of reducing ambiguity to a question of the intent of a “move,” and not grappling with its fundamental elusiveness.Meaning and Interpretation is a learned and helpfully provocative book, often written with great verve, but its value is more in the questions that it broaches than in the answers it offers. Raising questions is the proper Wittgensteinian and Jamesian activity: the book demonstrates by its own examples that offering definite answers may neutralize the power of the questions.William FleschBrandeis UniversityCopyright... (shrink)

Ludwig deals with the relations between language, thought, and rationality, and, especially, the role and status of assumptions about rationality in interpreting another’s speech and assigning contents to her psychological attitudes—her beliefs, desires, intentions, and so on. The chapter is organized around three questions: What is the relation between rationality and thought? What is the relation between rationality and language? What is the relation between thought and language? Ludwig argues that some large degree of rationality is required for (...) thought and consequently that same degree of rationality at least is required for language since language requires thought. Thought, however, does not require language. In answering questions and, Ludwig gives particular attention to Davidson’s arguments for the Principle of Charity, according to which it is constitutive of speakers that they are largely rational and largely right about the world, and to Davidson’s arguments for the thesis that without the power of speech we lack the power of thought. (shrink)

Abstract“Autonomous Sensory Meridian Response” (ASMR) refers to a sensory‐emotional experience that was first explicitly identified and named within the past two decades in online discussion boards. Since then, there has been mounting psychological and neural evidence of a clustering of properties common to the phenomenon of ASMR, including convergence on the set of stimuli that trigger the experience, the properties of the experience itself, and its downstream effects. Moreover, psychological instruments have begun to be developed and employed in an attempt (...) to measure it. Based on this empirical work, we make the case that despite its nonscientific origins, ASMR is a good candidate for being a real kind in the cognitive sciences. The phenomenon appears to have a robust causal profile and may also have an adaptive evolutionary history. We also argue that a more thorough understanding of the distinctive type of phenomenal experience involved in an ASMR episode can shed light on the functions of consciousness, and ultimately undermine certain “cognitive” theories of consciousness. We conclude that ASMR should be the subject of more extensive scientific investigation, particularly since it may also have the potential for therapeutic applications. (shrink)

Immanuel Kants "Grundlegung" ist ohne Zweifel einer der bedeutendsten Texte der abendlandischen Moralphilosophie. Sie gilt mitunter allerdings auch als einer der "dunkelsten" Texte Kants - wenn nicht sogar der abendlandischen Philosophie uberhaupt. Der Kommentar macht deutlich, dass die vorgebliche Dunkelheit im Wesentlichen der Tatsache geschuldet ist, dass der Text seit langem im Schatten der falschen Annahme gelesen wird, Kant wolle eine Begrundung (oder Rechtfertigung) des Sittengesetzes liefern, um damit den moralischen Skeptizismus abzuwehren. Liest man ihn stattdessen unter der (auch historisch (...) angemesseneren) Perspektive, dass Kant mit dem kategorischen Imperativ 'nur' eine neue Formel fur das Prinzip der allgemein im Schwange gehenden Sittlichkeit 'angeben und rechtfertigen' will, um so den moralischen Eudaimonismus durch eine Moral der Autonomie zu ersetzen - dann zeigt sich, dass der Text nicht bloss ein philosophisches, sondern zugleich ein schriftstellerisches Meisterwerk ist. (shrink)

El Concilio Vaticano II ofrece una teología del diaconado, al aludir a la condición diaconal de toda la Iglesia y, más en concreto, del ministerio ordenado. Esta diakonía se expresa pues en clave de servicio, y no de poder. En este artículo se responde a la pregunta de cuál es la diferencia con un laico, quien puede desempeñar funciones muy parecidas. La condición sacramental del diaconado ha sido enseñada siempre por la Tradición y el Magisterio de la Iglesia, mientras que (...) la doctrina del “carácter diaconal” como representación in persona Christi Servi sería más bien un desarrollo del magisterio posconciliar. El Concilio ha afirmado que el diácono ha sido ordenado non ad sacerdotium sed ad ministerium, para expresar la colaboración con los obispos, con sus presbíteros y con todo el Pueblo de Dios. Sirve a la mesa de los pobres, a la Mesa de la Palabra y a la Mesa eucarística. Su misión consiste en crear las condiciones para que la comunidad local se convierta en Iglesia y pueda así contar con e. (shrink)

Der Reader versammelt programmatische Ansätze der kulturwissenschaftlichen Auseinandersetzung mit dem Problem der Evidenz aus dem Blickpunkt der Sprach-, Geschichts-, Kunst- und Literaturwissenschaft, Medientheorie, Anthropologie und Soziologie. Mit Beiträgen u.a. von Rüdiger Campe, Iris Daermann, Egon Flaig, Peter Geimer, Vinzenz Hediger, Caspar Hirschi, Ludwig Jäger, Albrecht Koschorke, Helmut Lethen, Jakob Moser, Inka Mülder-Bach, Jan-Dirk Müller, Karl Schlögel, Florian Sprenger, Jakob Tanner, Marcus Twellmann, Juliane Vogel und Claus Zittel.

Neste texto, refero-me principalmente à forma madura da Ciência da Lógica, isto é, ao seu primeiro livro da edição revista do ano 1832. O objetivo de meu trabalho reside em demonstrar que a ilustração do problema do início da filosofia por Hegel é indiretamente uma chave para o entendimento da ideia fundamental de sua concepção da lógica como método científico da filosofia. Para atingir esse objetivo exponho, em primeiro lugar, as principais ideias do programa de Hegel por uma revisão da (...) lógica, da metafísica e da filosofia completa, em contraste à lógica tradicional. Depois ofereço uma interpretação da declaração da dificuldade em encontrar um início lógico na filosofia, que reside em que resolver o problema de unir o método ao conteúdo, a forma ao princípio. Essa interpretação deve mostrar no qual sentido o início vale sem pressuposto. Esse entendimento nega a possibilidade de começar a filosofia com algo hipotética e problematicamente verdadeiro como é o procedimento comum na matemática. Por meio da análise daquele problema ilustrado especialmente pelo exemplo da crítica hegeliana à compreensão da natureza da relação entre o ser puro e a sua alteração necessária em Jacobi, tento encontrar um acesso para o entendimento do método lógico de Hegel, na medida em que o momento da negatividade enquanto princípio do modo de determinar e, com isso, do conteúdo, resultam necessariamente da indeterminidade do ser como a mais pensável abstração. Esse resultado surge pela necessidade, por qual o ser puro provoca a sua própria mudança para o devir um desenvolvimento que Jacobi desmente por princípio para ficar parado na abstração unilateral e falsa. Assim, a indeterminidade enquanto algo contrário é mesmo o determinado ou o negativo, isto é, o negativo puro, inteiramente abstrato, em outras palavras: O ser como resultado da perfeita abstração é negatividade abstrata, o nada. Mas essa negatividade é o princípio e o método da determinação e do conhecer na lógica e na filosofia como ciência. (shrink)

In this chapter, the author uses the term ′ethics′ in a slightly wider sense, in a sense which includes an essential part of what is generally called ‘aesthetics’. The author says ′Ethics is the enquiry into what is valuable, or, into what is really important’, or ‘Ethics is the enquiry into the meaning of life, or into what makes life worth living, or into the right way of living’. If one looks at all these phrases, a rough idea is obtained (...) as to what it is that ethics is concerned with. Ethics, so far as it springs from the desire to say something about the ultimate meaning of life, the absolute good, the absolute valuable can be no science. But it is a document of a tendency in the human mind which the author personally cannot help respecting deeply. (shrink)

l. "Los axiomas de un sistema axiomático deben ser autoevidentes". ¿Cómo son, entonces, autoevidentes? ¿Qué ocurre si dijera: así es como lo encuentro mas fácil de imaginar. Y aquí imaginar no es un proceso mental particular en el cual uno cierra sus ojos o los cubre con las manos.

Uit familie-foto's en tekstfragmenten van brieven en aantekeningen samengestelde biografie van de Joods-Oostenrijkse, later in Engeland gevestigde wijsgeer (1889-1951).