Stem cells are likely to be used as an alternate source of biological material for neural transplantation to treat Parkinson’s disease in the not too distant future. Among the several ethical criteria that must be fulfilled before proceeding with clinical research, a favourable benefit to risk ratio must be obtained. The potential benefits to the participant and to society are evaluated relative to the risks in an attempt to offer the participants a reasonable choice. Through examination of preclinical studies transplanting (...) stem cells in animals and the transplantation of fetal tissue in patients with Parkinson’s disease, a current set of potential benefits and risks for neural transplantation of stem cells in clinical research of Parkinson’s disease are derived. The potential benefits to research participants undergoing stem cell transplantation are relief of parkinsonian symptoms and decreasing doses of parkinsonian drugs. Transplantation of stem cells as a treatment for Parkinson’s disease may benefit society by providing knowledge that can be used to help determine better treatments in the future. The risks to research participants undergoing stem cell transplantation include tumour formation, inappropriate stem cell migration, immune rejection of transplanted stem cells, haemorrhage during neurosurgery and postoperative infection. Although some of these risks are general to neurosurgical transplantation and may not be reduced for participants, the potential risk of tumour formation and inappropriate stem cell migration must be minimised before obtaining a favourable potential benefit to risk calculus and to provide participants with a reasonable choice before they enrol in clinical studies. (shrink)

"Epistola a Memeceo, Maximas capitales, Sentencias vaticanas, fragmentos y testimonios; texto griego y traduccion": p. [87]-161.

Łukasiewicz presented two different analyses of modal notions by means of many-valued logics: the linearly ordered systems Ł3,..., Open image in new window,..., \; the 4-valued logic Ł he defined in the last years of his career. Unfortunately, all these systems contain “Łukasiewicz type paradoxes”. On the other hand, Brady’s 4-valued logic BN4 is the basic 4-valued bilattice logic. The aim of this paper is to show that BN4 can be strengthened with modal operators following Łukasiewicz’s strategy for defining truth-functional (...) modal logics. The systems we define lack “Łukasiewicz type paradoxes”. Following Brady, we endow them with Belnap–Dunn type bivalent semantics. (shrink)

Digital transformation has allowed to offer additional services - which complement the main product - both in terms of use, emotional and relationship terms. Focused on a traditionally rational insurance customer offering a value that explores the customer's emotions, from co-creating with the user, allows brand differentiation. Given this idea, this document has three purposes. First, identify the role of expectations and the perceived quality of the customer's digital experience. Secondly, to identify the relationship between experience and satisfaction gained in (...) private insurance web areas. Third, identify the most valued digital attributes by the user. A sample of 4,178 customers registered was analyzed using the partial least squares technique. The model is highly predictive to customer experience and evidence the important relationship between the WOW effect and satisfaction, as well as the weak but doble role that expectations play on insurance digital self-service. The model demonstrates that expectations are only relevant before web consumption, because during the process it is the perceived digital quality, in particular the usefulness, information and technology, that offer a true customer experience. This article offers high academic value because it more accurately defines the determinants of the digital insurance customer experience and its effect on customer satisfaction in digital services. While expectations influence attitude before service, this research reveals that perceived digital quality is what delivers a true customer experience. Strategically, the implications are immediate in the field of business as it shows the importance of co-creation in digital design, not only because of the significant savings in implementation costs but also because it guarantees a greater experience, essential in the loyalty of its customers. This ensures the sustainable growth of the company. (shrink)

We provide all possible axiomatizations with independent axioms of E→ and R→ formulable with Anderson and Belnap’s list.

This paper offers a particular intuitionistic negation completion of Urquhart's system C resulting in a super-intuitionistic contractionless propositional logic equivalent to Dummett's LC without contraction.

A system S has the “converse Ackermann property” if -> C is unprovable in S whenever C is a propositional variable. In this paper we define the fragments with the C.A.P. of some well-know propositional systems in the spectrum between the minimal and classical logic. In the first part we succesively study the implicative and positive fragments and the full calculi. In the second, we prove by a matrix method that each one of the systems has the C.A.P. Thus, we (...) think the problem proposed in Anderson & Belnap § 8.12 has been solved. (shrink)

Let R+ be the positive fragment of Anderson and Belnap’s Logic of Relevance, R. And let RMO+ be the result of adding the Mingle principle ) to R+. We have shown in [2] that either a minimal negation or else a semiclassical one can be added to RMO+ preserving the variable-sharing property. Moreover, each of there systems is given a semantics in the Routley-Meyer style. In describing in [2] the models for RMO+ plus minimal negation, we noted that a similar (...) strategy would give us a semantics for R+ with minimal negation; that is, constructive R. The aim of this paper is to prove this claim. (shrink)

The logic TM is the result of adding the mingle axiom, M to Ticket Entailment logic, T. In the present study, it is proved that TM has the variable-sharing property . Ternary relational semantics for TM is provided. Finally, an interesting extension of TM with the vsp is briefly discussed.

The logic B+ is Routley and Meyer's basic positive logic. We show how to introduce a minimal intuitionistic negation and an intuitionistic negation in B+. The two types of negation are introduced in a wide spectrum of relevance logics built up from B+. It is proved that although all these logics have the characteristic paradoxes of consistency, they lack the K rule (and so, the K axioms).

A simple, bivalent semantics is defined for Łukasiewicz’s 4-valued modal logic Łm4. It is shown that according to this semantics, the essential presupposition underlying Łm4 is the following: A is a theorem iff A is true conforming to both the reductionist and possibilist theses defined as follows: rt: the value of modal formulas is equivalent to the value of their respective argument iff A is true, etc.); pt: everything is possible. This presupposition highlights and explains all oddities arising in Łm4.

The aim of this paper is to define the logical system Sm4 characterised by the degree of truth-preserving consequence relation defined on the ordered set of values of Smiley’s four-element matrix MSm4. The matrix MSm4 has been of considerable importance in the development of relevant logics and it is at the origin of bilattice logics. It will be shown that Sm4 is a most interesting paraconsistent logic which encloses a sound theory of logical necessity similar to that of Anderson and (...) Belnap’s logic of entailment E. Intuitively, Sm4 can be described as a four-valued expansion of the positive fragment of Lewis’ S5 or, alternatively, as a four-valued version of S5. (shrink)

Entendemos el concepto de “negación mínima” en el sentido clásico definido por Johansson. El propósito de este artículo es definir la lógica positiva mínima Bp+, y probar que la negación mínima puede introducirse en ella. Además, comentaremos algunas de las múltiples extensiones negativas de Bp+.“Minimal negation” is classically understood in a Johansson sense. The aim of this paper is to define the minimal positive logic Bp+ and prove that a minimal negation can be inroduced in it. In addition, some of (...) the many possible negation extensions of Bp+ are commented. (shrink)

The aim of this paper is to introduce an alternative to Łukasiewicz’s 4-valued modal logic Ł. As it is known, Ł is afflicted by “Łukasiewicz type paradoxes”. The logic we define, PŁ4, is a strong paraconsistent and paracomplete 4-valued modal logic free from this type of paradoxes. PŁ4 is determined by the degree of truth-preserving consequence relation defined on the ordered set of values of a modification of the matrix MŁ characteristic for the logic Ł. On the other hand, PŁ4 (...) is a rich logic in which a number of connectives can be defined. It also has a simple bivalent semantics of the Belnap–Dunn type. (shrink)

A prepositional logic S has the Converse Ackermann Property (CAP) if (AB)C is unprovable in S when C does not contain . In A Routley-Meyer semantics for Converse Ackermann Property (Journal of Philosophical Logic, 16 (1987), pp. 65–76) I showed how to derive positive logical systems with the CAP. There I conjectured that each of these positive systems were compatible with a so-called semiclassical negation. In the present paper I prove that this conjecture was right. Relational Routley-Meyer type semantics are (...) provided for each one of the resulting systems (the positive systems plus the semiclassical negation). (shrink)

ISSN:1909-9711 (En línea) Misión La Revista Acta Colombiana de Psicología publica hallazgos originales de las investigaciones en Psicología y de esta disciplina en diálogo con otras, con el propósito de divulgarlas a la comunidad universitaria y a todas las personas interesadas en conocer sus nuevos avances y aplicaciones a distintos campos y necesidades de la sociedad contemporánea.

Routley- Meyer type relational complete semantics are constructed for intuitionistic contractionless logic with reductio. Different negation completions of positive intuitionistic logic without contraction are treated in a systematical, unified and semantically complete setting.

La construcción de maquetas arquitectónicas como herramienta pedagógica aplicada en la etapa de bachillerato permite al estudiante comprender arquitectónicamente el edificio analizado, al mismo tiempo que aumenta su visión espacial, familiarizándose con el uso de planos de arquitectura. Además, el estudio histórico del edificio, en este caso, en el que ha desarrollado sus estudios en los últimos años, le inicia en el hábito de la investigación universitaria, implicándose desde el principio en conseguir los objetivos marcados, por lo que este tipo (...) de proyectos puede considerarse una interesante experiencia de enseñanza-aprendizaje. (shrink)

One of the main challenges in medicine is to guarantee an appropriate drug supply according to the real needs of patients. Closed-loop strategies have been widely used to develop automatic solutions based on feedback variables. However, when the variable of interest cannot be directly measured or there is a lack of knowledge behind the process, it turns into a difficult issue to solve. In this research, a novel algorithm to approach this problem is presented. The main objective of this study (...) is to provide a new general algorithm capable of determining the influence of a certain clinical variable in the decision making process for drug supply and then defining an automatic system able to guide the process considering this information. Thus, this new technique will provide a way to validate a given physiological signal as a feedback variable for drug titration. In addition, the result of the algorithm in terms of fuzzy rules and membership functions will define a fuzzy-based decision system for the drug delivery process. The method proposed is based on a Fuzzy Inference System whose structure is obtained through a decision tree algorithm. A four-step methodology is then developed: data collection, preprocessing, Fuzzy Inference System generation, and the validation of results. To test this methodology, the analgesia control scenario was analysed. Specifically, the viability of the Analgesia Nociception Index as a guiding variable for the analgesic process during surgical interventions was studied. Real data was obtained from fifteen patients undergoing cholecystectomy surgery. (shrink)

LCo with the Converse Ackermann Property is defined as the result of restricting Contraction in LC. Intuitionistic and Superintuitionistic Negation is shown to be compatible with the CAP.

Łukasiewicz 3-valued logic Ł3 is often understood as the set of all valid formulas according to Łukasiewicz 3-valued matrices MŁ3. Following Wojcicki, in addition, we shall consider two alternative interpretations of Ł3: ‘truth-preserving’ Ł3a and ‘well-determined’ Ł3b defined by two different consequence relations on the 3-valued matrices MŁ3. The aim of this article is to provide a Routley–Meyer ternary semantics for each one of these three versions of Łukasiewicz 3-valued logic: Ł3, Ł3a and Ł3b.

In his paper “Recent work in relevant logic”, Jago includes a section on Disjunctive Syllogism . The content of the section essentially consists of (a) a valuation of some work by Robles and Méndez on the topic as “not particularly interesting in itself”; (b) a statement establishing that “What would be interesting is to discover just how weak a relevant logic needs to be before disjunctive syllogism becomes inadmissible”. The main problem with this section of Jago’s paper on DS is (...) that the author is unaware of the recent important results on the topic. I show that (1) the valuation in (a) is groundless and (2) the ill-formulated problem in (b) is solved in the recent literature on relevant logics. (shrink)

En 1968 Raquel Carson comenzaba una revolución en el pensamiento, quizá una de las de mayor peso en la actualidad. En su libro "La primavera silenciosa" acusaba del deterioro ambiental al poder ilimitado del ser humano. La creencia surgida en la modernidad de que todo lo que el hombre decidía era en sí mismo lo mejor por haber sido fruto de una voluntad libérrima, daba primacía y legitimidad absoluta a su acción sobre la naturaleza. Surgieron con gran fuerza numerosos grupos (...) ecologistas que adoptaron un pensamiento que responde al nombre de "ecología profunda" o "Deep Ecology" descrito por primera vez por Arme Naess en un artículo publicado por la revista Inquiry y titulado "The Shallow and the Deep, Long Range Ecology Movement". Los principios que proponía este movimiento (Naess 1984) pueden ser resumidos en ocho grandes puntos: 1) la vida de los seres no humanos es un valor en sí: 2) la riqueza y la diversidad de estas formas de vida son también valores en sí; 3) los seres humanos no pueden intervenir de manera destructiva en la vida; 4) a este respecto, la intervención humana actual es eminentemente excesiva; 5) por consiguiente, las reglas de juego deben ser radicalmente modificadas; 6) esta modificación radical debe hacerse tanto a nivel de las estructuras económicas como de las estructuras ideológicas y culturales; 7) a nivel ideológico, el cambio principal consiste en apreciar más la calidad de la vida que el goce de los bienes materiales; 8) las personas que acepten estos principios tienen la obligación de contribuir, directa o indirectamente a la realización de los cambios fundamentales que aquellos implican. (shrink)

The aim of this paper is to provide a Routley-Meyer semantics for Ackermann’s logics of “strenge Implikation” Π ′ and Π ′′ . Besides the Disjunctive Syllogism, this semantics validates the rules Necessitation and Assertion. Strong completeness theorems for Π ′ and Π ′′ are proved. A brief discussion on Π ′ , Π ′′ and paraconsistency is included.

Etude de l'extension par la negation semi-intuitionniste de la logique positive des propositions appelee logique C, developpee par A. Urquhart afin de definir une semantique relationnelle valable pour la logique des valeurs infinies de Lukasiewicz (Lw). Evitant les axiomes de contraction et de reduction propres a la logique classique de Dummett, l'A. propose une semantique de type Routley-Meyer pour le systeme d'Urquhart (CI) en tant que celle-la ne fournit que des theories consistantes pour la completude de celui-ci.

S3o and S4o are the restrictions with the Converse Ackermann Property of the implicative fragments of Lewis' S3 and S4 respectively. The aim of this paper is to provide all possible axiomatizations with independent axioms of S3o and S4o that can be formulated with a modification of Anderson and Belnap's list of valid entailments.

Estamos siendo testigos de grandes avances tecnológicos y, a la vez, de grandes desastres naturales y sociales que nos impulsan a plantearnos cuáles son las causas últimas de la degradación natural ecológica. El abuso en el uso de los recursos tal vez pueda tener relación con el abuso en el uso de la tecnología; incluso ser causa de la gran desigualdad social en el acceso a bienes necesarios para llevar una vida digna, raíz de muchos conflictos sociales. La ecología es (...) una disciplina científica, pero cada vez es más habitual ampararse en este término para lanzar opiniones o generar un debate de ideologías de índole catastrofista que no hacen más que generar malestar social sin visos de solución práctica. Las reflexiones sobre la ecología nos parece que deben plantearse de una forma interdisciplinar, pero no de cualquier manera, sino respetando el estatuto epistemológico de cada área del saber. Cuidar el método científico, en el ámbito científico; el filosófico, en el suyo propio; e incluso el teológico. El tema de nuestra relación con la naturaleza nos afecta tan íntimamente que casi todas las áreas del conocimiento pueden decir algo al respecto. En el presente trabajo comenzamos ese diálogo y presentamos las ideas básicas desde las que se podría plantear un modo de actuar humano respetuoso para con los demás hombres y los demás seres de la naturaleza, que mejore nuestro modo de vivir y evite más daños y perjuicios. A esto nos referimos cuando hablamos de “ética ambiental”. La ecología nos toca de cerca porque tiene que ver con el modo de habitar nuestro mundo y las relaciones que tenemos con los demás seres vivos y no vivos. A fin de poder delinear las líneas principales de una ética orientada al medioambiente es preciso, en primer lugar, conocer los datos científicos sobre el tema; en segundo lugar, analizar los problemas graves que se están detectando y comprender que muchas de sus causas todavía son desconocidas y precisan de un estudio más detenido; finalmente, es conveniente revisar las alternativas de solución que nos orienten a llevar una vida mejor, donde se sugieran modos de obrar que no nos cierren el camino hacia ese destino común que tenemos como seres humanos, y que integre al resto de criaturas porque no somos los únicos seres vivientes del planeta. La propuesta de una “ética ambiental” apunta a considerar un verdadero “ecologismo solidario”. (shrink)

A classical result by Słupecki states that a logic L is functionally complete for the 3-element set of truth-values THREE if, in addition to functionally including Łukasiewicz’s 3-valued logic Ł3, what he names the ‘$T$-function’ is definable in L. By leaning upon this classical result, we prove a general theorem for defining binary expansions of Kleene’s strong logic that are functionally complete for THREE.

RMO -> is the result of adding the ‘mingle principle’ (viz. A-> (A -> A)) to Anderson and Belnap’s implicative logic of relevance R->. The aim of this paper is to provide all possible axiomatizations with independent axioms of RMO -> formulable with Anderson and Belnap’s list extended with three characteristic minglish principles.