Working memory (WM) deficits are pervasive co-morbidities of epilepsy. Although the pathophysiological mechanisms underpinning these impairments remain elusive, it is thought that WM depends on oscillatory interactions within and between nodes of large-scale functional networks. These include the hippocampus and default mode network as well as the prefrontal cortex and frontoparietal central executive network. Here, we review the functional roles of neural oscillations in subserving WM and the putative mechanisms by which epilepsy disrupts normative activity, leading to aberrant oscillatory signatures. (...) We highlight the particular role of interictal epileptic activity, including interictal epileptiform discharges and high frequency oscillations (HFOs) in WM deficits. We also discuss the translational opportunities presented by greater understanding of the oscillatory basis of WM function and dysfunction in epilepsy, including potential targets for neuromodulation. (shrink)

This paper focuses on the ethical and moral implications of findings from the authors? national survey of television news directors? policies, practices, and perceptions of good/bad news. In light of the potentially negative effects of excessive amounts of bad news on individuals and society, the authors ask whether television journalists have an ethical responsibility?beyond legal constraints and professional criteria?in the selection and presentation of bad news and good news. An earlier version of this paper, detailing the findings of the survey, (...) was presented to the Radio?TV Journalism Division of the Association for Education in Journalism and Mass Communication in August, 1986. (shrink)

RNA localization is a powerful strategy used by cells to localize proteins to subcellular domains and to control protein synthesis regionally. In germ cells, RNA targeting has profound implications for development, setting up polarities in genetic information that drive cell fate during embryogenesis. The frog oocyte offers a useful system for studying the mechanism of RNA localization. Here, we discuss critically the process of RNA localization during frog oogenesis. Three major pathways have been identified that are temporally and spatially separated (...) in oogenesis. Each pathway uses a different mechanism to effect RNA localization. In some cases, localization elements within the 3' untranslated region have been identified and have provided unique insights into the localization process. This important field is still in its infancy, however, and much remains to be learned. BioEssays 21:546–557, 1999. © 1999 John Wiley & Sons, Inc. (shrink)

Abstract‘Cruel optimism’ is a term coined by Lauren Berlant. In conceptualizing this term, Berlant draws on the resources of critical theory to interrogate people’s desires for things they think may improve their lot, but actually act as obstacles to flourishing. This notion may be useful for analysing the current state of education in Australia, and the desire to believe that My School, and the associated data it provides, will enable schools to address social inequalities. For Berlant, the promise of such (...) technologies is problematic because it diverts our attention from important ethical, social and political questions, some of which are highlighted in the contributions to this special issue. Using ‘cruel optimism’ as a point of departure, I interrogate how the notion of critical theory has been conceptualized in educational research by briefly looking at scholarship within and outside education relating to critical theory. Following on from this, I consider how what I am terming critical theory is put to work in each of the articles that make up this special issue on My School. (shrink)

This book engages contemporary debates about the notion of secularism outside of the field of education in order to consider how secularism shapes the formation of progressive sexuality education. Focusing on the US, Canada, Ireland, Aotearoa-New Zealand and Australia, this text considers the affinities, prejudices, and attachments of scholars who advocate secular worldviews in the context of sexuality education, and some of the consequences that ensue from these ways of seeing. This study identifies and interrogates how secularism infuses progressive sexuality (...) education. It asks readers to consider their own investments in particular ways of thinking and researching in the field of sexuality education, and to think about how these investments have developed and how they shape existing discourses within the field of sexuality education. It hones in on how progressive sexuality education has come to develop in the way that it has, and how this relates to conceits of secularism. This book prompts a consideration of how "progressive" scholarship and practice might get in the way of meaningful conversations with students, teachers, and peers who think differently about the field of sexuality education. (shrink)

If ‘a’ and‘b’are (proper) names and if the meaning of a name is exhausted by its referent, how can‘a = a’differ in cognitive value from‘a = b’if‘a = b’is true? This is Frege's famous puzzle and Bezuidenhout reconstructs it using demonstrative NPs in place of names, i.e.: This X is that X.’Her solution is to posit the‘truth-conditional relevance’of the de re modes of presentation of such expressions. My major objection is that Bezuidenhout's examples are such that the NP to the (...) right of the copula is anaphoric rather than demonstrative and cannot, therefore, support her argument. (shrink)

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Teaching in university education programmes, can, at times, involve the uncomfortable situation of discriminatory speech.A situation that has often occurred in our own teaching, and in those of our colleagues, is the citation of homophobic and heterosexist comments.These are comments that are more likely to occur in foundation subjects such as philosophy and sociology of education.The occurrence of such situations has prompted debate regarding ‘silencing words that wound’. This has prompted the question, ‘should we keep students from stating such discriminatory (...) speech?’ Our article takes up this issue, and considers it from the perspective of the importance of critique.Working with Foucault’s What is Critique? together with his discussion of subjectivation in the 1981–82 lectures at the Collège de France, we set out to make the case for the significance of the relationship between truth and critique.This leads us to a position where we ask the question, if we silence, what do we risk doing to critique? (shrink)

Ce texte s’inscrit dans le prolongement d’un effort endurci pour penser les modalités complexes du dialogue entre la psychanalyse lacanienne et la phénoménologie française dans la seconde moitié du xx e siècle. Plus exactement, il s’agit ici d’indiquer les raisons objectives, à la fois théoriques et pratiques, qui expliquent la violence de la réception française du De l’interprétation de Paul Ricœur, en mettant en perspective les positions respectives du philosophe et celles du psychanalyste Jacques Lacan lors du colloque de Bonneval (...) sur l’Inconscient d’octobre 1960. L’analyse détaillée du texte “Le conscient et l’inconscient” – élément du corpus ricœurien trop souvent négligé – au regard de l’enseignement lacanien du tournant des années 1960 doit en outre permettre de dégager deux théories de l’interprétation antagonistes, afin d’indiquer pour finir les points concrets de divergence entre les orientations “ricœurienne” et “lacanienne” de la clinique psychanalytique. (shrink)

In the next few years, biotechnology will continue to develop a wide variety of functional foods, foods whose benefits go well beyond basic nutrition. Minors are a major potential market for bioengineered foods that are promoted not as sustaining health but rather as supporting desired lifestyles through the enhancement of physical, athletic, intellectual, or social performance. The experience of other industries suggests that such biomarketing is likely to create a variety of highly public ethical controversies. After a discussion of some (...) of these potential issues, suggestions on how companies and industries can work with marketing ethicists and child advocates to limitnegative impacts on children and youth are presented. That discussion includes a preliminarily analysis of some of the considerations that should be involved in the initial development of a model of biomarketing ethics and in the use of that model to prevent ethical abuses. (shrink)

_The Cultural Politics of Queer Theory in Education Research_ represents the editors’ intention to disrupt cycles of thinking about the place of queer theory in educational research. The book aims to encourage dialogue about the objects and subjects of queer research, the forms of politics incited by the use of queer theory in education, and the methodological approaches used by scholars when queering. The contributions to this book come from those who find queer theory problematic, as well as from those (...) who continue to see a productive place for queer research in education, however that may be defined. The editors have collected contributions that attend to the boundaries that are placed around queer research in education by researchers themselves, and by peers, ethics committees, funding bodies and university and government bureaucracies. Considering how key researchers in gender and education identify with, or deliberately distance themselves from, queer theory, this collection grapples with the contemporary cultural politics of doing queer theoretical work in different education spaces and places. In short, it seeks to disrupt what people think they already know about the ‘place’ of queer theory in education. This book was originally published as a special issue of _Discourse: Studies in the Cultural Politics of Education. _. (shrink)

In her recent paper ‘The Epistemology of Propaganda’ Rachel McKinnon discusses what she refers to as ‘TERF propaganda’. We take issue with three points in her paper. The first is her rejection of the claim that ‘TERF’ is a misogynistic slur. The second is the examples she presents as commitments of so-called ‘TERFs’, in order to establish that radical (and gender critical) feminists rely on a flawed ideology. The third is her claim that standpoint epistemology can be used to establish (...) that such feminists are wrong to worry about a threat of male violence in relation to trans women. In Section 1 we argue that ‘TERF’ is not a merely descriptive term; that to the extent that McKinnon offers considerations in support of the claim that ‘TERF’ is not a slur, these considerations fail; and that ‘TERF’ is a slur according to several prominent accounts in the contemporary literature. In Section 2, we argue that McKinnon misrepresents the position of gender critical feminists, and in doing so fails to establish the claim that the ideology behind these positions is flawed. In Section 3 we argue that McKinnon’s criticism of Stanley fails, and one implication of this is that those she characterizes as ‘positively privileged’ cannot rely on the standpoint-relative knowledge of those she characterizes as ‘negatively privileged’. We also emphasize in this section McKinnon’s failure to understand and account for multiple axes of oppression, of which the cis/trans axis is only one. (shrink)

Background Advance Care Planning via Group Visits (ACP-GV) is a patient-centered intervention facilitated by a clinician using a group modality to promote healthcare decision-making among veterans. Participants in the group document a “Next Step” to use in planning for their future care needs. The next step may include documentation of preferences in an advance directive, discussing plans with family, or anything else to fulfill their ACP needs. This evaluation seeks to determine whether there are identifiable subgroups of group participants with (...) differing needs prior to delivery of the ACP-GV program and, if so, to use information about the subgroups to enhance the program offered to veterans in United States Department of Veterans Affairs (VA) healthcare settings. Methods We conducted a secondary analysis of national data from a quality improvement evaluation. Patient- and provider-level data from administrative healthcare records for VA users in all 50 states, territories, and the District of Columbia provides data on veterans attending ACP-GV during federal fiscal years 2018–2022 (N = 26,857). Latent class analysis seeks to identify the various subgroups of veterans based on their level of ACP self-efficacy before attending ACP-GV and any demographic differences across the resulting subgroups of veterans attending ACP-GV. ACP self-efficacy is derived from seven items obtained from a participant worksheet used during the group. Results Analysis revealed two distinct groups of veterans, distinguishable by their pre-ACP-GV levels of one aspect of ACP self-efficacy: prior knowledge of ACP. Veterans with higher prior knowledge of ACP are associated with an identified next step focused on checking their current AD status and updating it, and veterans with lower ACP prior knowledge are associated with identifying a next step to discuss ACP more fully with family. Differences in age, sex, race, ethnicity, and marital status exist across subgroups of veterans. Conclusion Greater attention must be paid to ACP and veterans’ prior knowledge of ACP to consistently encourage annual review and status updates. (shrink)

This paper explores violence in intimate relationships in one low-income community in the Western Cape, South Africa. In this community most intimate relationships (including parentchild, intimate partner relationships and friendships) seem to be characterized by anger, rage and also violence. In our analysis we discuss how the concepts of shame, guilt and the compulsion to repeat can serve to illuminate the seemingly inevitable link between violence and care in this specific community. It also seems that contextual factors such as class, (...) gender and race shape not only the form violence assumes, but also to whom it is directed. While we pay attention to the material and ideological conditions that shape the lives of individual storytellers, we also focus on the ways in which violence is represented in the individual stories. (shrink)

Laclau and Mouffe: The Radical Democratic Imaginary is the first full-length overview of the important work of Ernesto Laclau and Chantal Mouffe. Anna Marie Smith clearly shows how Laclau and Mouffe's work has brought Gramscian, poststructuralist and psychoanalytic perspectives to revitalize traditional political theory. With clarity and insight, she shows how they have constructed a highly effective theory of identity formation and power relations that carefully draws from the criticism of political theory from postmodern anti-foundationalist political theory.

An overview of the feminist theory literature on welfare policy and politics is presented. This introductory essay places a particular emphasis on the works that fall within the political sociology and normative political philosophy genres. In a lengthy digression, the article offers a tribute to the work of Iris Marion Young. It examines the centrality of her thinking about distribution, cultural marginalization, the welfare state bureaucracy, transnational responsibility and solidarity, and the pitfalls of maternalist discourse for this field. In the (...) conclusion, the article makes brief remarks about each of the contributions to the special issue on Feminist Theory and Welfare. (shrink)