BackgroundInvolvement of adolescent girls in biomedical HIV research is essential to better understand efficacy and safety of new prevention interventions in this key population at high risk of HIV infection. However, there are many ethical issues to consider prior to engaging them in pivotal biomedical research. In Uganda, 16–17-year-old adolescents can access sexual and reproductive health services including for HIV or other sexually transmitted infections, contraception, and antenatal care without parental consent. In contrast, participation in HIV prevention research involving investigational (...) new drugs requires adolescents to have parental or guardian consent. Thus, privacy and confidentiality concerns may deter adolescent participation. We describe community perspectives on ethical considerations for involving adolescent girls in the MTN 034 study in Uganda.MethodsFrom August 2017 to March 2018, we held five stakeholder engagement meetings in preparation for the MTN 034 study in Kampala, Uganda (NCT03593655): two with 140 community representatives, two with 125 adolescents, and one with 50 adolescents and parents. Discussions were moderated by the study team. Proceedings were documented by notetakers. Summary notes described community perspectives of adolescent participation in HIV research including convergent, divergent or minority views, challenges, and proposed solutions.ResultsMost community members perceived parental or guardian consent as a principal barrier to study participation due to concerns about adolescent disclosure of pre-marital sex, which is a cultural taboo. Of 125 adolescent participants, 119 (95%) feared inadvertent disclosure of sexual activity to their parents. Community stakeholders identified the following critical considerations for ethical involvement of adolescents in HIV biomedical research: (1) involving key stakeholders in recruitment, (2) ensuring confidentiality of sensitive information about adolescent sexual activity, (3) informing adolescents about information to be disclosed to parents or guardians, (4) offering youth friendly services by appropriately trained staff, and (5) partnering with community youth organizations to maximize recruitment and retention.ConclusionsStakeholder engagement with diverse community representatives prior to conducting adolescent HIV prevention research is critical to collectively shaping the research agenda, successfully recruiting and retaining adolescents in HIV clinical trials and identifying practical strategies to ensure high ethical standards during trial implementation. (shrink)

Initial vaccine allocations for the coronavirus disease 2019 (COVID-19) will be limited. It is crucial to assess the ethical values associated with different methods of allocation, as well as important scientific and practical questions. This Viewpoint identifies three ethical values, benefiting people and limiting harm; prioritizing disadvantaged populations; and equal concern for all. It then explains why these values support prioritizing three groups: health care workers; other essential workers and people in high-transmission settings; and people with medical vulnerabilities associated with (...) poorer COVID-19 outcomes. In contrast, two other groups, people over 65 without medical vulnerabilities and participants in clinical research, present more complex ethical questions. This prioritization also encompasses valuing direct benefits to vaccinated individuals, indirect benefits to individuals protected from spread of infection, and indirect health and socioeconomic benefits to those protected from harm as health system and societal functioning improve. Vaccine allocation that recognizes important ethical values and avoids arbitrariness, waste, and corruption can ensure that the distribution of a COVID-19 vaccine is both fair and perceived as fair. (shrink)

We introduce tame abstract elementary classes as a generalization of all cases of abstract elementary classes that are known to permit development of stability-like theory. In this paper, we explore stability results in this new context. We assume that [Formula: see text] is a tame abstract elementary class satisfying the amalgamation property with no maximal model. The main results include:. Theorem 0.1. Suppose that [Formula: see text] is not only tame, but [Formula: see text]-tame. If [Formula: see text] and [Formula: (...) see text] is Galois stable in μ, then [Formula: see text], where [Formula: see text] is a relative of κ from first order logic. [Formula: see text] is the Hanf number of the class [Formula: see text]. It is known that [Formula: see text]. The theorem generalizes a result from [17]. It is used to prove both the existence of Morley sequences for non-splitting and the following initial step towards a stability spectrum theorem for tame classes:. Theorem 0.2. If [Formula: see text] is Galois-stable in some [Formula: see text], then [Formula: see text] is stable in every κ with κμ=κ. For example, under GCH we have that [Formula: see text] Galois-stable in μ implies that [Formula: see text] is Galois-stable in μ+n for all n < ω. (shrink)

We prove that from categoricity in λ+ we can get categoricity in all cardinals ≥ λ+ in a χ-tame abstract elementary classe [Formula: see text] which has arbitrarily large models and satisfies the amalgamation and joint embedding properties, provided [Formula: see text] and λ ≥ χ. For the missing case when [Formula: see text], we prove that [Formula: see text] is totally categorical provided that [Formula: see text] is categorical in [Formula: see text] and [Formula: see text].

In 2011 the Journal of Moral Education (JME) celebrated its 40th anniversary of publication. It seemed appropriate to examine and reflect on the JME?s achievements by reviewing its evolution and contribution to the emerging field of moral education and development. Moral education trends, as reflected in the 945 articles published in JME from 1971 to 2011, were investigated by content analysis. The research objectives were: to discover the trends in moral education as represented by published articles and special issues (by (...) analysis of disciplinary approaches, key topics, research methodologies and age-related educational levels) and to examine the international and gender-related development of the journal and the influence of its contributors (by analysis of first authors and editorial board members). The findings identify important concerns, key research topics and neglected areas in moral education and development. Analysis offers an insight into the contribution of JME as the main international interdisciplinary journal in this field, to the history of moral education, to theory and practice and in the changing socio-cultural contexts of the past 40 years. Discussion of the findings is offered, limitations are acknowledged and implications for future directions for the journal considered. (shrink)

This article is an attempt to develop a measure of ethical sensitivity to racial and gender intolerance that occurs in schools. Acts of intolerance that indicate ethically insensitive behaviors in American schools were identified and tied to existing professional ethical codes developed by school-based professional organizations. The Racial Ethical Sensitivity Test consists of 5 scenarios that portray acts of racial intolerance and ethical insensitivity. Participants viewed 2 videotaped scenarios and then responded to a semistructured interview protocol adapted from Bebeau and (...) Rest. After a 2-week interval, this procedure was repeated. Stability of the REST across time was determined by using the overall test-retest coefficient. Internal as well as interrater consistency was also calculated for each scenario. Overall findings indicate promise for the REST as a reliable measure to assess racial and ethnic sensitivity. (shrink)

In this issue ofJME, Watsonet alcall for research evaluation of government health programmes and identify ethical guidance, including the Ottawa Statement on the ethical design and conduct of cluster randomised trials, as a hindrance. While cluster randomised trials of health programmes as a whole should be evaluated by research ethics committees (RECs), Watsonet alargue that the health programme per se is not within the researcher’s control or responsibility and, thus, is out of scope for ethics review. We argue that this (...) view is wrong. The scope of research ethics review is not defined by researcher control or responsibility, but rather by the protection of research participants. And the randomised evaluation of health programmes impacts the liberty and welfare interests of participants insofar as they may be exposed to a harmful programme or denied access to a beneficial one. Further, Watsonet al’s claim that ‘study programmes … would occur whether or not there were any … research activities’ is incorrect in the case of cluster randomised designs. In a cluster randomised trial, the government does not implement a programme as usual. Rather, researchers collaborate with the government to randomise clusters to intervention or control conditions in order to rigorously evaluate the programme. As a result, equipoise issues are triggered that must be addressed by the REC. (shrink)

This study concerned the role of gestures that accompany discourse in deep learning processes. We assumed that co‐speech gestures favor the construction of a complete mental representation of the discourse content, and we tested the predictions that a discourse accompanied by gestures, as compared with a discourse not accompanied by gestures, should result in better recollection of conceptual information, a greater number of discourse‐based inferences drawn from the information explicitly stated in the discourse, and poorer recognition of verbatim of the (...) discourse. The results of three experiments confirmed these predictions. (shrink)

The U.S. FDA has issued emergency use authorizations for monoclonal antibodies for non-hospitalized patients with mild or moderate COVID-19 disease and for individuals exposed to COVID-19 as post-exposure prophylaxis. One EUA for an oral antiviral drug, molnupiravir, has also been recommended by FDA’s Antimicrobial Drugs Advisory Committee, and others appear likely in the near future. Due to increased demand because of the Delta variant, the federal government resumed control over the supply and asked states to ration doses. As future variants (...) with increased infectivity and/or severity emerge, further rationing may be required. We identify relevant ethical principles and priority groups for access to therapies based on an integrated approach to population health and medical factors. Using priority categories to allocate scarce therapies effectively operationalizes important ethical values. This strategy is preferable to the current approach of categorical rules based on vaccination, immunocompromise status, or older age, or the ad hoc consideration of clinical risk factors. (shrink)

The goal of this article is to better understand the diffusion of environmentally preferable manufacturing technology (as distinct from pollution control technology) in small-and medium-sized firms (SMEs) and the influence of technical assistance programs on the diffusion of these technologies. The authors draw their insights from the printing industry, a sector where small firms predominate. They find that smaller firms lag slightly in the adoption of environmental technologies. With regard to technical assistance, they find that printers identify suppliers and other (...) industry sources as more useful than government in providing information that leads to active exploration of new environmental technologies. In addition, in comparison to larger firms, smaller firms reported to be less familiar with government-sponsored programs and perceived some of the programs to be less useful. They point to several ways in which regulatory agencies are experimenting to make government sponsored programs more effective. (shrink)

The possible integration of genomic sequencing (including whole‐genome and whole‐exome sequencing) into the three contexts addressed in this special report—state‐mandated screening programs, clinical care, and direct‐to‐consumer services—raises related but distinct legal issues. This essay will outline the legal issues surrounding the integration of genomic sequencing into state newborn screening programs, parental rights to refuse and access sequencing for their newborns in clinical and direct‐to‐consumer care, and privacy‐related legal issues attending the use of sequencing in newborns.

Although the field of surgical ethics focuses primarily on informed consent, surgical decision‐making, and research ethics, some surgeons have started to consider ethical questions regarding justice and solidarity with poor and minoritized populations. To date, those calling for social justice in surgical care have emphasized increased diversity within the ranks of the surgical profession. This article, in contrast, foregrounds the agency of those most affected by injustice by bringing to bear an ethic of accompaniment. The ethic of accompaniment is born (...) from a theological tradition that has motivated work to improve health outcomes in those at the margins through its emphasis on listening, solidarity against systemic drivers of disease, and proximity to individuals and communities. Through a review of surgical ethics and exploration of a central patient case, we argue for applying an ethic of accompaniment to the care of surgical patients and their communities. (shrink)

Abstract:Water lilies flourish in clusters and hormonally communicate together within their community. They can self-reproduce and have mobility across the water surface, being both earthed and waterborne. The capacities of water lilies are further evidence that plants require critical and cultural examination, as companion species, and that plants require an accompanying shift in human perception of their vegetal status. This paper addresses the feminist nature of the water lily and develops a connection between plant biology and the creation of models (...) for cultural practice, ethical living and a better understanding of plants. (shrink)

Este artigo pretende abordar os impactos que a vivência do racismo dentro do ambiente familiar tem na subjetividade dos indivíduos. Interpela, portanto, os modos como essa experiência interfere na formação da identidade do sujeito, na sua autoimagem e na construção da estima por si mesmo. Esses processos, múltiplos e complexos, serão observados a partir da análise do relato das histórias e experiências de vida de uma pessoa, Mariana. Embora trate de Mariana, através de sua voz, muitos outros falam. Muitas famílias (...) brasileiras estão aqui representadas, na vivência dolorida de muitas mulheres e homens que experimentaram o racismo desde a tenra infância. Contado e vivificado por ela, assim como interpretado à luz dos significantes e significados que ela atribui a essas vivências, seu relato permite pensar os efeitos psicossociais da experiência da violência racial e do racismo quando ele é vivido pelos sujeitos negros nos arranjos familiares em que o branco da família é explicitamente racista. (shrink)

Business Ethics, the Environment & Responsibility, Volume 31, Issue 2, Page 419-437, April 2022.

Resumen En este trabajo se analizan 19 fórmulas rutinarias del español peninsular que comparten un mismo esquema sintáctico (Vete a+sintagma nominal o Vete a+sintagma verbal) y que se describen en los diccionarios como expresiones “de rechazo” hacia el interlocutor. Con base en las clasificaciones existentes, estas expresiones podrían considerarse fórmulas “subjetivas”, “afectivas” o “expresivas actitudinales”, ya que sirven para mostrar la actitud y las emociones del hablante. Sin embargo, conceptos complejos como “expresión afectiva”, “actitudinal” o “de rechazo” no resultan muy (...) esclarecedores a la hora de explicar el significado de este tipo de expresiones a hablantes de otras lenguas o de otras variedades del español. Por otro lado, dado que el español peninsular cuenta con al menos 19 expresiones de este tipo, es razonable pensar que entre ellas puedan existir algunas diferencias de significado. El presente estudio pretende dar respuesta a estas dos cuestiones mediante la aplicación de la Metalengua Semántica Natural (NSM) al análisis semántico-pragmático de estas unidades. Este trabajo ofrece un primer acercamiento a este tipo de expresiones mediante la elaboración de explicaciones semántico-pragmáticas para los diferentes grupos de fórmulas que, con base en los ejemplos encontrados, se han establecido en el estudio. (shrink)

Owing to unique features of their design, cluster randomized trials complicate the interpretation of standard ethics guidelines. The recently published Ottawa statement on the ethical design and conduct of cluster randomized trials provides researchers and research ethics committees with detailed guidance on the design, conduct and review of cluster trials. The Ottawa statement sets out 15 recommendations, including guidance on the justification of study design, the need for research ethics committee review, the identification of research participants, obtaining informed consent, the (...) role of gatekeepers in protecting cluster interests, the assessment of benefits and harms, and the protection of vulnerable participants. (shrink)

This research aims to study possible effects or impacts of COVID-19 in the context of a democratic organizational system analyzing how COVID-19 has influenced employees’ perception of their participation in decision-making and its impact on some psychological outcomes and emotions. COVID-19 has accelerated the process of implementation of new frameworks at work that have generated the modification of culture and employee management practices. Our hypothesis are, on the one hand, that COVID-19 has generated changes in participation structures and internal communication (...) mechanisms, having to make modifications not to deteriorate the perception of employees about their participation in decision making. On the other hand, COVID-19 has generated changes in the psychological outcomes and emotions of the employees. In the study, we analyze a cooperative belonging to the MONDRAGON cooperative group, where participation in decision-making and ownership is in its DNA. Through qualitative and quantitative methodologies, involving 42 employees, we investigate firstly, how COVID-19 has affected perceptions about participation in decision-making analyzing what role has played internal communication in these perceptions. Secondly, we investigate how COVID-19 has affected psychological outcomes and emotions. In this case, the perceptions arising from participation in decision-making focus on the assessment that participators make of the governance channels and the day-to-day meetings. Therefore, their appropriateness seems to be a key factor in the perception of participation in the COVID-19 era. Differences have been detected between the perceptions of blue and white collar employees. Such differences have also been founded in the psychological outcomes and emotions. Although this is a single case study, the analysis carried out provides elements of reflection to modify and restructure the decision-making and participation mechanisms, adapting them to the needs of blue and white collar employees in order to “guarantee” the expected outcomes. (shrink)

Dans la littérature arabe médiévale, il existe une façon spécifique de mourir à cause d’une passion amoureuse, liée à la conception d’un amour chaste qui possède ses propres valeurs et qui ne peut s’exprimer que dans les limites de ses propres règles. Le présent article étudie les vers récités par les amants avant d’exhaler leur dernier souffle contenus dans une vingtaine de notices d’al-Wāḍiḥ al-mubīn fī ḏikr man ustušhida min al-muḥibbīn (ou Précis des martyrs de l’amour) de Mughulṭāy (m. 1361). (...) En analysant les situations dans lesquelles ces vers sont prononcés, nous avons essayé de comprendre s’il existe (ou non) une manière spécifique, déclinée au féminin, d’exprimer son émotion avant de mourir. (shrink)

Le choix de l’unité statistique de segmentation du corpus, ainsi que celui de la distance entre les réponses, induit une structure sur l’ensemble des réponses. Nous proposons d’appliquer une méthodologie statistique, l’analyse factorielle multiple pour tableaux de contingence, AFMTC, pour, d’une part, comparer les structures induites sur un même corpus par différentes unités statistiques et, d’autre part, définir une distance entre textes capable de prendre en compte différentes unités et de profiter ainsi de l’information véhiculée par chacune d’elles. Pour présenter (...) cette méthodologie, généralisation de l’analyse des correspondances aux tableaux de contingence multiples, on utilise une enquête auprès de femmes divorcées qui comporte une question ouverte sur les raisons de leur divorce. Comparison between the structures that are induced by the choice of the statistical unitThe election of the statistical unit, as well as that of the distance between responses, induces a structure on the whole of the responses. We propose to apply a statistical methodology, the multiple factorial analysis for contingency table, MFACT, in order to, on the one hand, compare the structures induced on a same corpus by different statistical units and, on the other hand, define a distance between texts able to take into account different units and so take advantage of the information that they convey. To present this methodology, a generalisation of correspondence analysis to multiple contingency tables, we use a survey carried out on divorced women, that includes an open-ended question about the reasons of their divorce. (shrink)

Ionizing radiation is present in various situations in the contemporary world. Defining the quantities and units for this field is a complex scientific task, especially the quantities used in radiological protection (RP) to estimate the damage caused to individuals exposed to radiation (detriment). This article highlights the lack of consensus in the scientific RP community regarding the quantities and units employed in practice from the perspective of the philosophy of science. The basic concepts related to the system of quantities are (...) presented, followed by the problems and criticisms addressed by experts in the field. Several reasons for these problems are identified. The article discusses the scant interest on the part of philosophy of science in RP. The philosophy of science is still dominated by an analytical–conceptual perspective that pays little attention to the actual influence of certain structures better understood when considered from the institutional viewpoint, which is here exemplified by the International Commission on Radiological Protection (ICRP) and the International Atomic Energy Agency (IAEA). (shrink)

Method as Identity considers how social identity shapes methodological standpoints. With a refreshing hip hop sensibility, Miller and Driscoll reorient the contemporary academic study of religion toward recognition of the costs and benefits of manufacturing “critical” distance from our objects of study.

The construction of body image consists of the ways in which the body is considered, perceived, and evaluated. The ideal body image has been changing considerably over the centuries; the discrepanc...

This paper discusses the similarities and differences between sociological and Christian approaches regarding the relationship between materialism and life satisfaction. The theoretical analysis gives reasons that advocate the view that there are resemblances between the two perspectives regarding materialism features and the impact of these values on life satisfaction. Both approaches argue for a less materialistic way of life in order to become generally happier. Nevertheless, if science gives research-based proofs to this relationship, Christianity states that worship of God, and (...) not material goods, is the only way to get true happiness. Finally, the paper attempts to give some possible explanations for these similarities between sociology and Christianity. First, similarly to the Christian religion, some sociologists criticise materialism and consumption society. Second, the scale construction can rely on popular notions of materialism, thus some items can have religious backgrounds. Eventually, the Bible and the Church Fathers’ special concern with the human nature lead to some thoughts about man that have been confirmed by researchers. (shrink)

A mediados del siglo xvii, Girolamo Graziani publica en Módena Il Conquisto di Granata, un poema épico de 26 cantos en los que se narran los acontecimientos que rodearon el asedio del Reino de Granada en sus últimos diez años. Este poema, por tanto, describe el ambiente caballeresco y el tema de la lucha entre cristianos y musulmanes a través de múltiples episodios en los que no faltan los fieros y gigantescos moros, las doncellas guerreras y toda suerte de fábulas (...) y encantamientos. En este estudio determinaremos la arquitectura espacial de este poema épico, definiendo la ciudad de Granada como centro de todo movimiento, en el que todas las acciones se valorarán y medirán a partir de la distancia y de la relación que tengan con ese lugar. Au milieu du xviie siècle, Girolamo Graziani publie à Modène Il Conquisto di Granata, un poème épique de 26 chansons qui raconte les événements des dix dernières années du siège du royaume de Grenade. Ce poème décrit donc l’atmosphère chevaleresque et la lutte entre chrétiens et musulmans en plusieurs épisodes où abondent Maures féroces et gigantesques, jeunes filles guerrières, fables diverses et enchantements. Cette étude porte sur l’architecture spatiale de cette épopée, la définition de la ville de Grenade en tant que centre de tout mouvement, l’évaluation et la mesure de toutes les actions en fonction de la distance et de la relation qu’elles ont avec ce lieu. (shrink)

Genetic counselors are on the front lines of the genetic revolution, presented with tests of varying predictive values and reliability, unfair testing distribution mechanisms, tests for conditions where no treatment exists, and companies that oversell the usefulness of their tests to physicians and nurses. Many scholars, both genetic testing task forces as well as the newly formed National Bioethics Advisory Commission, have all noted that genetic counseling programs and services are critical for adequate genetic testing. At the same time, in (...) our own work at the University of Pennsylvania we have encountered many requests for new materials for training genetic counselors in ethics and providing ethics resources for genetic counseling. One of us has noted elsewhere that it is crucial that resources from the Human Genome Project, the Centers for Disease Control, and other public agencies be devoted to providing better resources for genetic counselors facing difficult ethical issues. Although the American Board of Genetic Counseling requires that training programs include some formal coursework in ethics, many wonder whether enough is being done to prepare genetic counselors for an ever-tougher job, and in particular there has been much concern expressed about whether is an outmoded ideal that hampers this profession as it attempts to grow and identify the value of its practice. On the basis of many comments to us by genetic counselors and on the basis of our review of the current literature, we hypothesized that accredited genetic counseling training programs are poised at the turn of the century to begin planning a new approach toteaching the philosophy of genetic counseling, one that integrates philosophical, theoretical, and ethical training throughout thecurriculum in genetic counseling. (shrink)

Rorty holds that it is possible to defend a liberal democratic policy without having to substantiate it according to universal criteria linked to corresponding notions of truth, instead, he affirms that this democratic policy can be founded on a notion of truth narrowly linked to justification. Following this idea one would expect Rorty to take a position committed to pluralism understood in a strong sense, where different positions are justified and validated in relation to specific existential conditions, however, this does (...) not happen. As we will demonstrate, Rorty´s proposal, although it is partly inspired by Nietzsche´s perspectivism, as well as the ethical-political reading of plurality based on Wittgenstein´s proposal of language games, it goes no further than a contextualized pretence which is not based on a real posture of pluralism. In this article we maintain that the Rortian position, far from being pluralist, tends toward ethno-centrism and even domination through persuasion. (shrink)

O presente artigo propõe uma reflexão sobre a campanha "Pichação é Crime. Denuncie.", iniciativa da Associação Comercial do Paraná e da Prefeitura Municipal de Curitiba que mobilizaram esforços na repressão da pichação. A campanha buscou associar a pichação ao vandalismo e o pichador a um ser desprezível que emporcalha a cidade, representado pelo personagem Zé Sujeira. É possível identificar na codificação da campanha a reprodução do discurso dominante que tem impacto apenas em parte da sociedade.

The book presents insights from a mixed methodology study that examines recent mobility patterns exhibited by the middle classes. Its major contributions are two-fold: theoretically, it advances the conceptualisation of middle class migration; empirically, it analyses the migratory motivations of a relatively new Latin-American group in Australia. The accelerated insertion of the Mexican society into globalisation processes is strongly linked not only to the growing participation in migration phenomena but also to people's outflow to new destinations. Although studies of Mexican (...) emigration are vast, research on Mexican skilled migration is scarce, and research that focuses on mobility to non-USA destinations is even scarcer. Mexicans are a relatively new addition to Australia's multicultural society, and little is known about this group's profile and why they choose to migrate to Australia. Employing a mixed methodology approach, the book provides a comprehensive portrait of migration in a new group. (shrink)

The mortality rate of patients affected with oral squamous cell carcinoma has been stable in recent decades due to several factors, especially diagnostic delay, which is often associated with a late stage diagnosis and poor prognosis. The aims of this paper were to: analyze diagnostic delay in OSCC and to discuss the various psychological factors of patients with OSCC, with particular attention to the patient’s fear of receiving news regarding their health; and the professional dynamics related to the decision-making processes (...) in cases of suspected OSCC. A preliminary review of literature focusing on OSCC diagnostic delay was performed. Seven articles were included with the diagnostic delay ranging from 45 days to approximately 6 months. Patients’ fears and, to a lesser degree, the concerns of dentists, were found to be still poorly investigated. On the basis of the authors’ professional experience, the development of oral lesions of unknown origin may generate different behaviors in the decision-making processes by patients and clinicians, and fear may play a key role in the distinct steps of this process. It is crucial to increase awareness and inform patients about the onset of OSCC, and contemporaneously encourage experimental studies on patients’ fear and professional behaviors with respect to communication regarding OSCC. (shrink)