BackgroundBiobanks have recently been established in several low- and middle-income countries in the Arab region of the Middle East. We aimed to explore the views of biobank managers regarding the challenges, ethical issues, and governance arrangements of their biobanks.MethodsIn-depth semi-structured qualitative interviews were conducted with a purposive sample of eight biobank managers from Egypt, Jordan, and Sudan. Interviews were performed either face-to-face, by phone, or via Zoom and lasted approximately 45–75 min. After verbal consent, interviews were recorded and then transcribed. (...) The authors performed a thematic analysis of the transcripts independently and then integrated the themes via a consensus process.ResultsBiobank managers discussed the main challenges in establishing their biobanks. These included the staff’s lack of experience and training, limited funds, deficit awareness of biobanks, obtaining funding from different sources. Only four reported they were active in distributing biospecimens and health data to researchers. Six biobanks used a broad consent model, one used tiered consent, and another allowed participants to opt-out of being recontacted. Five managers avoided partnerships with pharmaceutical companies due to concerns with unfavorable reactions from the community. Five managers did not have clear policies for returning research results to the donors. Five expressed challenges with sample and data sharing with international collaborators; all five used material transfer agreements. The biobank managers revealed variable governance arrangements and activities with community involving awareness and educational efforts rather than active engagement. Several expressed the importance of transparency with the operations of their biobanks and gaining the trust of their stakeholders.ConclusionManagers of biobanks in LMICs in the Arab Middle East encounter financial, operational, and social challenges toward their sustainability efforts. Discussions with key stakeholders are warranted to manage ethical issues involving informed consent, privacy, data sharing, and the return of results. We recommend that biobank managers in the Arab Middle East form collaborative networks within the region and internationally, develop trusting governance relationships with their stakeholders, and pursue engagement activities with their communities to enhance trust. (shrink)

This study analyzes how the board’s characteristics could be associated with globally corporate social responsibility CSR and specific areas of CSR. It is drawn on all listed firms, in 2016, on the SBF120 between 2003 and 2016. Our results provide strong evidence that diversity in boards and diversity of boards globally are positively associated with corporate social performance. However, they influence differently specific dimensions of CSR performance. First, we show that large boards are positively associated with all areas of CSR (...) performance, while specific and overall CSR scores are negatively associated with CEO-chair structures. Second, board gender diversity is positively associated with human rights and corporate governance dimensions. Third, age diversity is positively associated with corporate governance, human resources, human rights, and environmental activities. Also, our results provide evidence that outside directors care about CSR performance. Specifically, the presence of foreign directors is positively associated with environmental performance and community involvement, whereas CSR-Governance dimension is positively associated with the presence of independent directors. Regarding the director’s educational level, post-graduated directors are positively and significantly associated with overall CSR score and all CSR sub-scores, except the corporate governance one. When directors have multiple directorships, they are more concerned about human resources, environmental performance, and business ethics. Finally, our findings are robust only in non-family firms. In fact, family boards are less diverse than non-family ones; specifically, they have a lower number of independent, foreign, and high-educated directors. (shrink)

Kuhn’s famous thesis that there is ‘no unique algorithm’ for choosing between rival scientific theories is analysed using the machinery of social choice theory. It is shown that the problem of theory choice as posed by Kuhn is formally identical to a standard social choice problem. This suggests that analogues of well-known results from the social choice literature, such as Arrow’s impossibility theorem, may apply to theory choice. If an analogue of Arrow’s theorem does hold for theory choice this would (...) refute Kuhn’s thesis, but it would also pose a threat to the rationality of science, a threat that is if anything more worrying than that posed by Kuhn. Various possible ‘escape routes’ from Arrow’s impossibility result are examined, in particular Amartya Sen’s idea of ‘enriching the informational basis’. It is shown that Sen’s idea can be applied to the problem of theory choice in science. This in turn sheds light on two well-known approaches to inductive inference in philosophy of science: Bayesianism and statistical model selection. (shrink)

Derrida and the Inheritance of Democracy provides a theoretically rich and accessible account of Derrida's political philosophy. Demonstrating the key role inheritance plays in Derrida’s thinking, Samir Haddad develops a general theory of inheritance and shows how it is essential to democratic action. He transforms Derrida’s well-known idea of "democracy to come" into active engagement with democratic traditions. Haddad focuses on issues such as hospitality, justice, normativity, violence, friendship, birth, and the nature of democracy as he reads these deeply (...) political writings. (shrink)

The COVID-19 emergency has hit the whole world, finding all countries unprepared to face it. The first studies focused on the medical aspects, neglecting the psychological dimension of the populations that were forced to face changes in everyday life and in some cases to stay forcedly at home in order to reduce contagion. The present research was carried out in Italy, one of the countries hardest hit by the pandemic. The aim was to analyze the perception of happiness, mental health, (...) and the sense of loneliness experienced by adults during the lockdown due to the COVID pandemic. Specifically, the variables will be examined in relation to gender difference, living alone, with partner, or with partner and children. The research followed a quantitative approach using an online questionnaire. The project involved 1100 subjects from whom 721 participants were extrapolated. Of them, 17.3% claimed to live alone, 39.5% with their partner, and 43.1% with their partner and children. The results show that people in general experienced a lower level of happiness and mental health and higher levels of loneliness compared to normative sample. The lockdown and pandemic condition due to COVID-19 seems to have canceled the gender differences in the perception of happiness and mental health, while it seems to have increased the perception of loneliness experienced by males compared to the pre-pandemic condition. In addition, those who lived alone perceived a greater level of loneliness than those who lived with their partner or partner and children. Unexpectedly, no significant differences emerged regarding the level of happiness and mental health between those who had direct contact with the virus and those who did not. These data should make political decision-makers reflect on the need to pay more attention to the implications that such drastic measures as a lockdown can have on people’s psychological well-being. (shrink)

Today, anxiety is usually thought of as a pathology, the most diagnosed and medicated of all psychological disorders. But anxiety isn't always or only a medical condition. Indeed, many philosophers argue that anxiety is a normal, even essential, part of being human, and that coming to terms with this fact is potentially transformative, allowing us to live more meaningful lives by giving us a richer understanding of ourselves. In Anxiety, Samir Chopra explores valuable insights about anxiety offered by ancient (...) and modern philosophies-Buddhism, existentialism, psychoanalysis, and critical theory. Blending memoir and philosophy, he also tells how serious anxiety has affected his own life-and how philosophy has helped him cope with it. Chopra shows that many philosophers-including the Buddha, Kierkegaard, Nietzsche, Freud, and Heidegger-view anxiety as an inevitable human response to existence: to be is to be anxious. Drawing on Karl Marx and Herbert Marcuse, Chopra examines how poverty and other material conditions can make anxiety worse, but he emphasizes that not even the rich can escape it. Nor can the medicated. Inseparable from the human condition, anxiety is indispensable for grasping it. Philosophy may not be able to cure anxiety but, by leading us to greater self-knowledge and self-acceptance, it may be able to make us less anxious about being anxious. Personal, poignant, and hopeful, Anxiety is a book for anyone who is curious about rethinking anxiety and learning why it might be a source not only of suffering but of insight. (shrink)

Such obvious truth must be made even more obvious, and this is exactly what Samir Selmanovic is doing for all of us and for the future of humanity.

We consider the question: under what circumstances can the concept of adaptation be applied to groups, rather than individuals? Gardner and Grafen (2009, J. Evol. Biol.22: 659–671) develop a novel approach to this question, building on Grafen's ‘formal Darwinism’ project, which defines adaptation in terms of links between evolutionary dynamics and optimization. They conclude that only clonal groups, and to a lesser extent groups in which reproductive competition is repressed, can be considered as adaptive units. We re-examine the conditions under (...) which the selection–optimization links hold at the group level. We focus on an important distinction between two ways of understanding the links, which have different implications regarding group adaptationism. We show how the formal Darwinism approach can be reconciled with G.C. Williams’ famous analysis of group adaptation, and we consider the relationships between group adaptation, the Price equation approach to multi-level selection, and the alternative approach based on contextual analysis. (shrink)

This is a conversation that took place at Dr. Vladimir Safatle’s São Paulo home on 16 February, 2019, during Dr. Samir Gandesha’s time as a Visiting Professor at the Faculdade de Filosofia, Letras e Ciências Humanas -FFLCH-USP. It addresses the South American roots of the authoritarian Neoliberalism that has now become a truly global phenomenon.

Does natural selection act primarily on individual organisms, on groups, on genes, or on whole species? The question of levels of selection - on which biologists and philosophers have long disagreed - is central to evolutionary theory and to the philosophy of biology. Samir Okasha's comprehensive analysis gives a clear account of the philosophical issues at stake in the current debate.

Abstract: This study aimed to identify the reality of using a balanced scorecard in business incubators in Gaza Strip, and the study relied on the descriptive analytical approach, and the study population consisted of all employees working in business incubators in Gaza Strip in addition to experts and consultants in incubators, where their total number reached (62) Individually, the researchers used the questionnaire as a main tool for collecting data through the comprehensive survey method, where (55) questionnaires were retrieved with (...) a recovery rate (88.7%.). The results of the study showed that there is a high approval of all dimensions of the balanced scorecard, as it obtained a relative weight (81.44%), and the order of its dimensions came as follows, first came the incubation dimension with a relative weight (84.89%), followed by the learning dimension, which got a relative weight (82.50%), and in the third place came the entrepreneur dimension with a relative weight (80.66%), and in the last place was the societal development dimension with a relative weight (78.18%). The study came out with several recommendations, the most important of which is that business incubators seek to adopt the application of the balanced scorecard as a method for managing it and a tool for measuring and evaluating its performance, and the need to periodically evaluate its performance, and the need to hold training courses for workers in incubators to introduce them to the balanced scorecard and how to apply it. (shrink)

What is science? Is there a real difference between science and myth? Is science objective? Can science explain everything? This Very Short Introduction provides a concise overview of the main themes of contemporary philosophy of science. Beginning with a short history of science to set the scene, Samir Okasha goes on to investigate the nature of scientific reasoning, scientific explanation, revolutions in science, and theories such as realism and anti-realism. He also looks at philosophical issues in particular sciences, including (...) the problem of classification in biology, and the nature of space and time in physics. The final chapter touches on the conflicts between science and religion, and explores whether science is ultimately a good thing. (shrink)

Virtual reality allows participants to experience immersive perspective-taking which is key to stimulate empathy and emotion sharedness. Immersive interaction performed by the participants is examined in this article as an experience of cultural embodiment. Following a biosemiotic approach to culture, the study examines the virtual reality movie Waves of Grace qualitatively. It seeks to trace how participants’ interaction with the virtual worlds elicits in them a feeling of being embodied in a world of Ebola suffering that is outside the cultural (...) paradigm of their real world. Biosemiotics provides a theoretical platform which helps in deconstructing the complexity of participants’ kinetic interactions within both physical and virtual spaces, and, in a way, reconstructing the concept of cultural embodiment. Correspondingly, the analysis yields that cultural embodiment is instantiated through kinetic movement and rhythmical interaction where participants are not only told about the story of Ebola but inhabit its umwelt and reconfigure it. Enacting an umwelt-to-umwelt interaction, participants not only alter the visual scenes and affect their affordances, but they also model subjective worlds that scaffold how they feel, and how they relate to the virtual situation. The findings suggest to update the metaphors used to understand the ‘viewing’ of suffering and sufferers (most notably among them is spectatorship of suffering and distant suffering). The world of suffering is embodied rather than communicated. The article makes a contribution to biosemiotic cultural studies by introducing the concept of physical-virtual kinetic rhythms to the notion of cultural embodiment. (shrink)

In this paper we analyze the use of swearwords in Greek teenage storytelling. Our research is based on the analysis of conversational narratives that occurred in two conversations between male adolescents who belong to different social groups. Our analysis shows that the use of swearing in the story performances enables the narrators (1) to construct for themselves the identity of the powerful members of a group who share strong friendship bonds and challenge authorities in the first conversation, and (2) to (...) project the identity of individuals who conform to mainstream values in the second conversation. Therefore, we suggest that swearing can be an effective linguistic tool for the construction and negotiation of diverse youth identities, i.e. the acceptance of or the departure from social norms, in the unfolding of narrative speech. (shrink)

Samir Okasha offers a critical study of agential thinking in biology, where evolved organisms are seen as agents pursuing a goal. He examines the justification for transposing concepts from rational humans to the biological world, and considers whether agential thinking is mere anthropomorphism or plays a more intellectual role in the science.

Every year, unfavorable environmental factors significantly affect crop productivity and threaten food security. Plants are sessile; they cannot move to escape unfavorable environmental conditions, and therefore, they activate a variety of defense pathways. Among them are processes regulated by stress‐associated proteins (SAPs). SAPs have a specific zinc finger domain (A20) at the N‐terminus and either AN1 or C2H2 at the C‐terminus. SAP proteins are involved in many biological processes and in response to various abiotic or biotic constraints. Most SAPs play (...) a role in conferring transgenic stress resistance and are stress‐inducible. The emerging field of SAPs in abiotic or biotic stress response regulation has attracted the attention of researchers. Although SAPs interact with various proteins to perform their functions, the exact mechanisms of these interactions remain incompletely understood. This review aims to provide a comprehensive understanding of SAPs, covering their diversity, structure, expression, and subcellular localization. SAPs play a pivotal role in enabling crosstalk between abiotic and biotic stress signaling pathways, making them essential for developing stress‐tolerant crops without yield penalties. Collectively, understanding the complex regulation of SAPs in stress responses can contribute to enhancing tolerance against various environmental stresses through several techniques such as transgenesis, classical breeding, or gene editing. (shrink)

Let T and T1 be tournaments with n elements, E a basis for T, E′ a basis for T′, and k ≥ 3 an integer. The dual of T is the tournament T” of basis E defined by T = T for all x, y ε E. A hemimorphism from T onto T′ is an isomorphism from T onto T” or onto T. A k-hemimorphism from T onto T′ is a bijection f from E to E′ such that for any (...) subset X of E of order k the restrictions T/X and T1/f are hemimorphic. The set of hemimorphisms of T onto itself has group structure, this group is called the group of hemimorphisms of T. In this work, we study the restrictions to n – 2 elements of a tournament with n elements. In particular, we prove: Let k ≥ 3 be an integer, T a tournament with n elements, where n ≥ k + 5. Then the following statements are equivalent: All restrictions of T to subsets with n – 2 elements are k-hemimorphic. All restrictions of T to subsets with n – 2 elements are 3-hemimorphic. All restrictions of T to subsets with n – 2 elements are hemimorphic. All restrictions of T to subsets with n – 2 elements are isomorphic, Either T is a strict total order, or the group of hemimorphisms of T is 2-homogeneous. (shrink)

The importance of this dictionary stems from Quatreme're's profound reflections on the nature of architecture: on the principles which are at the source of his rules and on the roles of imitation and invention within tradition. This book provides the first English translation of the theoretical essays from his seminal work, Le Dictionnaire Historique d' Architecture.

In this essay I examine Derrida’s proposal for a new understanding of responsibility in the university, as it is articulated in “Mochlos, or The Confl ict of the Faculties,” together with remarks made in “The Principle of Reason: The University in the Eyes of its Pupils” and “The University Without Condition”. I argue that this account of responsibility, while sharing some characteristics with Derrida’s later theorizations, enacts an inheritance of Kant and places an emphasis on community that is unique in (...) Derrida’s oeuvre. (shrink)

Nosso trabalho procura descrever a escola cinica atraves de seu fundador; Antistenes de Atenas (444-355) , analisando o comportamento do homem cinico e suas contradiçõess, sua busca pela virtude e pelo agir correto. Mostramos o caminho que o homem cinico deve percorrer para chegar a seu objetivo : a autarquia. Ao mesmo tempo, revelamos seu repúdio a toda cultura estabelecida e a sua relaçáo com o corpo e o prazer. O cínico deve distanciarse da cidade, das atividades mundanas e da (...) politica. (shrink)

The pandemic nature of COVID-19 has caused major changes in health, economy, and society globally. Albeit to a lesser extent, contingent access to shops and places to socialize the imposition of social distancing and the use of indoor masks is measures still in force today, with repercussions on economic, social, and psychological levels. The fear of contagion, in fact, has led us to be increasingly suspicious and to isolate ourselves from the remainder of the community. This has had repercussions on (...) the perception of loneliness, with significant psychological consequences, such as the development of stress, anxiety, and, in extreme cases, depressive symptoms. Starting from these assumptions, this research was developed with the aim of deepening the perceptions that the participants have of their own mental health, loneliness, fear linked to contagion, and attitudes toward imposed social distancing. In particular, we wanted to analyze whether there is a relationship between perceived fear and the perceived level of mental health, loneliness, and attitude toward social distancing. Finally, we wanted to analyze whether there are differences related to gender, age, marital status, current working mode, and educational qualifications. The research, performed after the diffusion of the vaccination in Italy, lasted 14 days. The participants were 500 Italians who voluntarily joined the study and were recruited with random cascade sampling. The research followed a quantitative approach. The analyzed data, from participants residing throughout the national territory, allow us to return the picture of the perceptions that Italians have of the fear of contagion, of their level of mental health, of loneliness and of their attitude toward social distancing. In particular, the data show that fear of COVID-19 is an emotional state experienced by the entire population and that young people have suffered more from loneliness and have been less inclined to accept the imposed social distancing. The data that emerged should make policymakers reflect on the need to find functional strategies to combat COVID-19 or other health emergency crises whose effects do not affect the psychological wellbeing of the population. (shrink)

This paper focuses on the concept of sunna, and its great theoretical and historical complexity. The term “sunna” seems nowadays to be a label for the whole set of behaviors adopted by believers, from simple details of dress or diet to the most elaborate of ritual and cultural attitudes. The daily lifestyle of the prophet is invoked so as to imitate the way he washed, how he lay down to sleep, or “sat at table”, not to mention his ritual gestures (...) during prayer, what he preferred to eat after breaking fasts, his slightest movements over the nights and days of pilgrimage. The author intends to show on the contrary, through an unprecedented study, that the Islamic society of a very large city, that of 10th century Baghdad, was for a considerable period of time completely disengaged from such obsessive scrupulousness of religious observance. It gives large evidence of this phenomenon, and tries to outline the historical reasons how the sunna eventually evolved into a rule defining the coercive power of the Islamic faith. (shrink)

Biological agency has received much attention in recent philosophy of biology. But what is the motivation for introducing talk of agency into biology and what is meant by “agent”? Two distinct motivations can be discerned. The first is that thinking of organisms as agents helps to articulate what is distinctive about organisms vis-à-vis other biological entities. The second is that treating organisms as agent-like is a useful heuristic for understanding their evolved behavior. The concept of agent itself may be understood (...) in at least four different ways: minimal agent, intelligent agent, rational agent, and intentional agent. Which understanding is most appropriate depends on which of the two motivations we are concerned with. (shrink)

Routledge (New Media and Cyberculture Series), July 2007.

This study explores gratitude as a multidimensional and work-specific construct. Utilizing a sample of 625 employees from a variety of positions in a medium-sized school district in the United States, we developed and evaluated a new measure, namely the Work Gratitude Scale, which encompasses recognized conative, cognitive, affective, and social aspects of gratitude. A systematic, six-phased approach through structural equation modeling was used to explore and confirm the factorial structure, internal consistency, measurement invariance, concurrent, convergent, and discriminant validity of the (...) WGS. The results supported a 10-item measure with three dimensions: “grateful appraisals”, “gratitude toward others”, and “intentional attitude of gratitude”. Thereafter, first-order, second-order, and bifactor confirmatory models were estimated and compared. Work gratitude was found to be best described by a second-order construct with three underlying first-order dimensions. Measurement invariance was supported in relation to gender. Concurrent validity was supported in relation to two existing dispositional gratitude scales, namely the Gratitude Questionnaire and the Gratitude, Resentment, and Appreciation Scale. Convergent validity was supported in relation to the Core Self-Evaluations Scale and the Psychological Capital Questionnaire. Discriminant validity was supported in relation to various demographic factors such as age, gender, occupation, and tenure. The findings support the WGS as a multidimensional measure that can be used in practice to measure overall work-related gratitude and to track the effectiveness of gratitude-related workplace interventions. (shrink)

Abstract:This paper explores the contrast between mentalistic and behaviouristic interpretations of decision theory. The former regards credences and utilities as psychologically real, while the latter regards them as mere representations of an agent's preferences. Philosophers typically adopt the former interpretation, economists the latter. It is argued that the mentalistic interpretation is preferable if our aim is to use decision theory for descriptive purposes, but if our aim is normative then the behaviouristic interpretation cannot be dispensed with.

Hox proteins are part of the conserved superfamily of homeodomain‐containing transcription factors and play fundamental roles in shaping animal body plans in development and evolution. However, molecular mechanisms underlying their diverse and specific biological functions remain largely enigmatic. Here, we have analyzed Hox sequences from the main evolutionary branches of the Bilateria group. We have found that four classes of Hox protein signatures exist, which together provide sufficient support to explain how different Hox proteins differ in their control and function. (...) The homeodomain and its surrounding sequences accumulate nearly all signatures, constituting an extended module where most of the information distinguishing Hox proteins is concentrated. Only a small fraction of these signatures has been investigated at the functional level, but these show that approaches relying on Hox protein alterations still have a large potential for deciphering molecular mechanisms of Hox differential control. (shrink)