Recent scientific advances in the field of gene editing have led to a renewed discussion on the moral acceptability of human germline modifications. Gene editing methods can be used on human embryos and gametes in order to change DNA sequences that are associated with diseases. Modifying the human germline, however, is currently illegal in many countries but has been suggested as a ‘last resort’ option in some reports. In contrast, preimplantation genetic diagnosis is now a well-established practice within reproductive medicine. (...) Both methods can be used to prevent children from being born with severe genetic diseases. This paper focuses on four moral concerns raised in the debate about germline gene editing and applies them to the practice of PGD for comparison: Violation of human dignity, disrespect of the autonomy and the physical integrity of the future child, discrimination of people living with a disability and the fear of slippery slope towards immoral usage of the technology, e.g. designing children for specific third party interests. Our analysis did not reveal any fundamental differences with regard to the four concerns. We argue that with regard to the four arguments analyzed in this paper germline gene editing should be considered morally as acceptable as the selection of genomes on the basis of PGD. However, we also argue that any application of GGE in reproductive medicine should be put on hold until thorough and comprehensive laws have been implemented to prevent the abuse of GGE for non-medical enhancement. (shrink)

Karl Leonhard Reinhold<br>Versuch einer neuen Theorie des Vorstellungsvermögens, Teilband 1<br>Einleitung, Vorrede, Erstes Buch<br><br>Mit einer Einleitung und Anmerkungen herausgegeben von Ernst-Otto Onnasch.<br>PhB 599a. 2010. CLVII, 210 Seiten.<br>978-3-7873-1934-3. Leinen 68.00<br><br>Karl Leonhard Reinholds Versuch einer neuen Theorie des menschlichen Vorstellungsvermögens (1789) ist aufgegliedert in eine lange Vorrede und drei Bücher. In der Vorrede und im ersten Buch stellt der Autor die epochale Bedeutung der kritischen Philosophie heraus. Im zweiten Buch folgt die eigentliche Theorie des Vorstellungsvermögens, von der aus im dritten Buch Kants (...) wichtigste Entdeckungen in der Kritik der reinen Vernunft, nämlich die Unterscheidung von Sinnlichkeit, Verstand und Vernunft, neu dargestellt werden. Hier liefert Reinhold eine eigene und höchst originelle Ableitung der Kategorien und der Ideen.<br><br>In seiner Einleitung beschreibt der Herausgeber Reinholds philosophische Entwicklung und erweist ihn als einen eigenständigen Denker mit einer ganz eigenen philosophischen Agenda, die er allerdings auf eine sehr geschickte Weise mit dem philosophischen Anliegen Kants zu verbinden vermochte: Reinholds Philosophie war, entgegen der überkommenen Einschätzung, alles andere als epigonal und von enormer Bedeutung für die Ausprägung und Genese der Philosophie des deutschen Idealismus.<br><br>Bereits mit seinen populären Briefen über die Kantische Philosophie (1786/87) traf Reinhold den Nerv der Zeit und setzte damit die kritische Philosophie Kants für ein breiteres Publikum auf die philosophische Agenda (nur wenige der Zeitgenossen lasen Kant im Original, die meisten bezogen ihr Urteil über Kant aus den Briefen). Der Versuch einer neuen Theorie des menschlichen Vorstellungsvermögens ist dann sein erstes großes theoretisches Werk mit eigenem Anspruch. Reinhold präsentiert es als einen Versuch, die kritische Philosophie auf der Grundlage des Vorstellungsvermögens allgemein verständlich zu machen.<br>. (shrink)

Diese Ausagabe macht Buchbesprechungen wieder zugänglich, die in verschiedenen Zeitschriften vom Ende des 18. Jahrhunderts verstreut erschienen sind und deswegen schwer erreichbar waren. Sie sammelt alle Dokumente, in denen von mehr oder minder bekannten Zeitgenossen Einwände gegen die Elementarphilosophie erhoben wurden, auf die Reinhold selbst in seinen Büchern antwortete. Auf diese Weise wird ein philosophischer Kontext geschildert, in dem einzelne Konstellationen deutlich werden, die sich wechselseitig widerrufen und widerlegen. Viele der zeitgenössischen Rezensionen beinhalten auBerdem einen Vergleich zwischen der Kantischen (...) und der Reinholdschen Philosophie; die vorliegende Ausgabe bringt insofern Bewertungen von Kants theoretischem Unternehmen zum Ausdruck, als dieses meistens per Kontraposition zur Elementarphilosophie, aber auch direkt beurteilt wird--Back cover. (shrink)

Reinhold's Letters on the Kantian Philosophy is arguably the most influential book ever written concerning Kant. It provides a helpful introduction to Kant's philosophy and a valuable explanation of how that philosophy can be understood as an appropriate Enlightenment solution to the 'pantheism dispute' which dominated thought in the era of German Idealism. The first edition of Kant's Critique of Pure Reason was slow in gaining a positive reception, but after Reinhold's Letters appeared Kant's Critical Philosophy suddenly attained (...) the central position which it has held to this day. The Letters also brought fame to Reinhold, who developed his own influential 'Elementary Philosophy' and was succeeded by the leading figures of German Idealism: Fichte, Schelling, and Hegel. This English edition of Reinhold's work includes the original 1786–7 version as well as all the major additions and changes from the 1790 edition. (shrink)

Forthright and realistic, [this book] discusses the inevitability of social conflict, the brutal behavior of human collectives of every sort, the inability of ...

This 1935 book answered some of the theological questions raised by Moral Man and Immoral Society (1932) and articulated for the first time Niebuhr's theological position on many issues.

Humans are incapable of acting as utility maximisers. In contrast, the evolutionary process had considerable time and computational power to select optimal heuristics from a set of alternatives. To view evolution as the optimising agent has revolutionised game theory. Gigerenzer and his co-workers can help us understand the circumstances under which evolution and learning achieve optimisation and Nash equilibria.

This self-contained essay collection is published to commemorate half a century of Bell's theorem. Like its much acclaimed predecessor "Quantum [Un]Speakables: From Bell to Quantum Information" (published 2002), it comprises essays by many of the worlds leading quantum physicists and philosophers. These revisit the foundations of quantum theory as well as elucidating the remarkable progress in quantum technologies achieved in the last couple of decades. Fundamental concepts such as entanglement, nonlocality and contextuality are described in an accessible manner and, alongside (...) lively descriptions of the various theoretical and experimental approaches, the book also delivers interesting philosophical insights. The collection as a whole will serve as a broad introduction for students and newcomers as well as delighting the scientifically literate general reader. (shrink)

Volume V covers the period from September 1530 to May 1531. It therefore mainly contains information about Bucer¹s diplomatic journey after the Augsburg Diet, his correspondence with the Valdesian synod of Mérindol, his attempts to mediate between Luther and Zwingli with the help of his Konkordienschrift and to integrate the Swiss party in the Schmalcaldic confederation.

Wegen des großen Anteils an Einzelkorrespondenten in Bucers Briefwechsel von September 1532 bis Juni 1533 versammelt dieser Band eine Vielzahl von Anliegen. Bucer soll etwa bei Stellenbesetzungen vermitteln, für säumige Schuldner eintreten, seine exegetischen Werke zusenden, einen Trostbrief schreiben, zur Visitation kommen, mittellosen Autoren zum Druck ihrer Bücher verhelfen oder schlicht Fürbitte einlegen.

The building of a socialist society requires a personality developed in all respects, active in the social sense, possessing a scientific world-view, and capable of mastering the process of its own life. At the Eighth Congress of the Socialist Unity Party and at subsequent plenums of the Central Committee, these questions attracted very great attention. The task of our Party lies in indissolubly associating the further development of the socialist personality with the growth of the productive forces, the continuing improvement (...) of socialist relationships, and the total flourishing of socialist culture. (shrink)

_The Children of Light and the Children of Darkness_, first published in 1944, is considered one of the most profound and relevant works by the influential theologian Reinhold Niebuhr, and certainly the fullest statement of his political philosophy. Written and first read during the prolonged, tragic world war between totalitarian and democratic forces, Niebuhr’s book took up the timely question of how democracy as a political system could best be defended. Most proponents of democracy, Niebuhr claimed, were “children of (...) light,” who had optimistic but naïve ideas about how society could be rid of evil and governed by enlightened reason. They needed, he believed, to absorb some of the wisdom and strength of the “children of darkness,” whose ruthless cynicism and corrupt, anti-democratic politics should otherwise be repudiated. He argued for a prudent, liberal understanding of human society that took the measure of every group’s self-interest and was chastened by a realistic understanding of the limits of power. It is in the foreword to this book that he wrote, “Man’s capacity for justice makes democracy possible; but man’s inclination to injustice makes democracy necessary.” This edition includes a new introduction by the theologian and Niebuhr scholar Gary Dorrien in which he elucidates the work’s significance and places it firmly into the arc of Niebuhr’s career. (shrink)

“[Niebuhr] is one of my favorite philosophers. I take away [from his works] the compelling idea that there’s serious evil in the world, and hardship and pain. And we should be humble and modest in our belief we can eliminate those things. But we shouldn’t use that as an excuse for cynicism and inaction. I take away... the sense we have to make these efforts knowing they are hard.”—President Barack Obama Forged during the tumultuous but triumphant postwar years when America (...) came of age as a world power, The Irony of American History is more relevant now than ever before. Cited by politicians as diverse as Hillary Clinton and John McCain, Niebuhr’s masterpiece on the incongruity between personal ideals and political reality is both an indictment of American moral complacency and a warning against the arrogance of virtue. Impassioned, eloquent, and deeply perceptive, Niebuhr’s wisdom will cause readers to rethink their assumptions about right and wrong, war and peace. “The supreme American theologian of the twentieth century.”—Arthur Schlesinger Jr., New York Times “Niebuhr is important for the left today precisely because he warned about America’s tendency—including the left’s tendency—to do bad things in the name of idealism. His thought offers a much better understanding of where the Bush administration went wrong in Iraq.”—Kevin Mattson, The Good Society “Irony provides the master key to understanding the myths and delusions that underpin American statecraft.... The most important book ever written on US foreign policy.”—Andrew J. Bacevich, from the Introduction. (shrink)

Journal Name: Philologus Issue: Ahead of print.

What do the technical practices, procedures, and systems that have shaped institutions of higher learning in the United States, from the Ivy League and women's colleges to historically black colleges and land-grant universities, teach us about the production and distribution of knowledge? Addressing media theory, architectural history, and the history of academia, Knowledge Worlds reconceives the university as a media complex comprising a network of infrastructures and operations through which knowledge is made, conveyed, and withheld. Reinhold Martin argues that (...) the material infrastructures of the modern university-the architecture of academic buildings, the configuration of seminar tables, the organization of campus plans-reveal the ways in which knowledge is created and reproduced in different kinds of institutions. He reconstructs changes in aesthetic strategies, pedagogical techniques, and political economy to show how the boundaries that govern higher education have shifted over the past two centuries. From colleges chartered as rights-bearing corporations to research universities conceived as knowledge factories, educating some has always depended upon excluding others. Knowledge Worlds shows how the division of intellectual labor was redrawn as new students entered, expertise circulated, science repurposed old myths, and humanists cultivated new forms of social and intellectual capital. Combining histories of architecture, technology, knowledge, and institutions into a critical media history, Martin traces the uneven movement in the academy from liberal to neoliberal reason. (shrink)