The principles of the 3Rs—replacement, refinement, and reduction—strongly shape discussion of methods for performing more humane animal research and the regulation of this contested area of technoscience. This special issue looks back to the origins of the 3Rs principles through five papers that explore how it is enacted and challenged in practice and that develop critical considerations about its future. Three themes connect the papers in this special issue. These are the multiplicity of roles enacted by those who use and (...) care for animals in research, the distribution of “feelings that matter” across species and spaces of laboratory animal practice, and the growing importance of “cultures of care” in animal research. (shrink)

Natural selection is commonly interpreted as the fundamental mechanism of evolution. Questions about how selection theory can claim to be the all-sufficient explanation of evolution often go unanswered by today's neo-Darwinists, perhaps for fear that any criticism of the evolutionary paradigm will encourage creationists and proponents of intelligent design.In Biological Emergences, Robert Reid argues that natural selection is not the cause of evolution. He writes that the causes of variations, which he refers to as natural experiments, are independent of (...) natural selection; indeed, he suggests, natural selection may get in the way of evolution. Reid proposes an alternative theory to explain how emergent novelties are generated and under what conditions they can overcome the resistance of natural selection. He suggests that what causes innovative variation causes evolution, and that these phenomena are environmental as well as organismal.After an extended critique of selectionism, Reid constructs an emergence theory of evolution, first examining the evidence in three causal arenas of emergent evolution: symbiosis/association, evolutionary physiology/behavior, and developmental evolution. Based on this evidence of causation, he proposes some working hypotheses, examining mechanisms and processes common to all three arenas, and arrives at a theoretical framework that accounts for generative mechanisms and emergent qualities. Without selectionism, Reid argues, evolutionary innovation can more easily be integrated into a general thesis. Finally, Reid proposes a biological synthesis of rapid emergent evolutionary phases and the prolonged, dynamically stable, non-evolutionary phases imposed by natural selection. (shrink)

How do thought and language manage to be 'about' aspects of the world? J. Robert G. Williams investigates how representation arises out of a fundamentally non-representational world, showing the explanatory relations between the representational properties of language, of thought, and of perception and intention.

The ontological status of sport: Weiss, P. Records and the man. Schacht, R. L. On Weiss on records, athletic activity, and the athlete. Fraleigh, W. P. On Weiss on records and on the significance of athletic records. Stone, R. E. Assumptions about the nature of movement. Suits, B. The elements of sport. Kretchmar, S. Ontological possibilities: sport as play. Morgan, W. An existential phenomenological analysis of sport as a religious experience. Fraleigh, W. P. The moving "I." Fraleigh, W. P. Some (...) meanings of the human experience of freedom and necessity in sport. Keenan, F. W. The concept of doing.--The ethical status of sport: Keating, J. W. The ethics of competition and its relation to some moral problems in ahtletics. Sadler, W. A., Jr. A contextual approach to an understanding of competition: a response to Keating's philosophy of athletics. Osterhoudt, R. G. On Keating on the competitive motif in athletics and playful activity. Suits, B. The grasshopper: a thesis concerning the moral idea of man. Broekhoff, J. Sport and ethics in the context of culture. Zeigler, E. F. The pragmatic (experimentalistic) ethic as it relates to sport and physical education. Roberts, T. J. and Galasso, P. J. The fiction of morally indifferent acts in sport. Osterhoudt, R. G. The Kantian ethic as a principle of moral conduct in sport and athletics. Thomas, C. E. Do you "wanna" bet: an examination of player betting and the integrity of the sporting event.--The aesthetic status of sport: Kuntz, P. G. The aesthetics of sport. Keenan, F. W. The athletic contest as a "tragic" form of art. Osterhoudt, R. G. An Hegelian interpretation of art, sport, and athletics. (shrink)

The six essays in this volume discuss philosophical thought on scientific theory including: a call for a realist, rather than instrumentalist interpretation of science; a critique of one of the core ideas of positivism concerning the relation between observational and theoretical languages; using aerodynamics to discuss the representational aspect of scientific theories and their isomorphic qualities; the relationship between the reliability of common sense and the authenticity of the world view of science; removing long-held ambiguities on the theory of inductive (...) logic; and the relationship between the actuality of conceptual revolutions in the history of science and traditional philosophical pictures of scientific theory-building. (shrink)

Theoretical explication of a growing body of empirical data on consciousness-related anomalous phenomena is unlikely to be achieved in terms of known physical processes. Rather, it will first be necessary to formulate the basic role of consciousness in the definition of reality before such anomalous experience can adequately be represented. This paper takes the position that reality is constituted only in the interaction of consciousness with its environment, and therefore that any scheme of conceptual organization developed to represent that reality (...) must reflect the processes of consciousness as well as those of its environment. In this spirit, the concepts and formalisms of elementary quantum mechanics, as originally proposed to explain anomalous atomic-scale physical phenomena, are appropriated via metaphor to represent the general characteristics of consciousness interacting with any environment. More specifically, if consciousness is represented by a quantum mechanical wave function, and its environment by an appropriate potential profile, Schrödinger wave mechanics defines eigenfunctions and eigenvalues that can be associated with the cognitive and emotional experiences of that consciousness in that environment. To articulate this metaphor it is necessary to associate certain aspects of the formalism, such as the coordinate system, the quantum numbers, and even the metric itself, with various impressionistic descriptors of consciousness, such as its intensity, perspective, approach/avoidance attitude, balance between cognitive and emotional activity, and receptive/assertive disposition. With these established, a number of the generic features of quantum mechanics, such as the wave/particle duality, and the uncertainty, indistinguishability, and exclusion principles, display metaphoric relevance to familiar individual and collective experiences. Similarly, such traditional quantum theoretic exercises as the central force field and atomic structure, covalent molecular bonds, barrier penetration, and quantum statistical collective behavior become useful analogies for representation of a variety of consciousness experiences, both normal and anomalous, and for the design of experiments to study these systematically. (shrink)

The revolution involving the foundations of the physical sciences heralded by relativity and quantum theories has been stimulating philosophers for many years. Both of these comprehensive sets of concepts have involved profound challenges to traditional theories of epistemology, ontology, and language. This volume gathers six experts in physics, logic and philosophy to discuss developments in space exploration and nuclear science and their impact on the philosophy of science.

THIS PAPER ARGUES, AGAINST A. O. LOVEJOY AND WITH R. B.\nPERRY, THAT JAMES' THEORY OF MEANING DOES NOT CONFUSE\nCONSEQUENCES OF BELIEVING AND CONSEQUENCES OF THE\nSTATEMENTS BELIEVED. RATHER, I ARGUE THAT JAMES HOLDS THAT\nTHE MEANING OF A SYNTHETIC STATEMENT IS TO BE FOUND IN ITS\nPERCEPTUAL CONSEQUENCES WHILE CONSEQUENCES OF BELIEVING ARE\nRELEVANT TO 'JUSTIFYING' OVERBELIEFS; THAT IS, TO\nJUSTIFYING MEANINGFUL STATEMENTS FOR WHICH THE EVIDENCE IS\nINSUFFICIENT TO PROVIDE A RATIONAL, NON-PASSIONAL\nJUSTIFICATION. ALTHOUGH THIS THEORY OF MEANING APPEARS\nANTI-METAPHYSICAL, JAMES DOES NOT USE IT TO RULE (...) OUT\nMETAPHYSICS BECAUSE HE BELIEVES, ALONG WITH COMMON SENSE,\nTHAT METAPHYSICAL DOCTRINES ARE MEANINGFUL; THUS, THE\nQUESTION IS WHAT METAPHYSICAL DOCTRINES MEAN AND NOT\nWHETHER THEY ARE MEANINGFUL. ALTHOUGH JAMES IS OFTEN\nMISLEADING IN TALKING ABOUT MEANING, I ARGUE THAT THIS\nINTERPRETATION IS SUPPORTED BY HIS NUMEROUS DISCUSSIONS OF\nMETAPHYSICS. PAUL HENLE'S ATTEMPT TO PROVIDE A FAVORABLE\nINTERPRETATION OF JAMES WITHIN LOVEJOY'S FRAMEWORK, IS ALSO\nSHOWN TO BE INCOHERENT. (shrink)

Seeking a scientific basis for understanding and treating mental illness, and inspired by the work of Ivan Pavlov, American physiologists, psychiatrists and psychologists in the 1920s turned to nonhuman animals. This paper examines how new constructs such as “experimental neurosis” emerged as tools to enable psychiatric comparison across species. From 1923 to 1962, the Cornell “Behavior Farm” was a leading interdisciplinary research center pioneering novel techniques to experimentally study nonhuman psychopathology. Led by the psychobiologist Howard Liddell, work at the Behavior (...) Farm formed part of an ambitious program to develop new preventative and therapeutic techniques and bring psychiatry into closer relations with physiology and medicine. At the heart of Liddell’s activities were a range of nonhuman animals, including pigs, sheep, goats and dogs, each serving as a proxy for human patients. We examine how Pavlov’s conceptualization of ‘experimental neurosis’ was used by Liddell to facilitate comparison across species and communication between researchers and clinicians. Our close reading of his experimental system demonstrates how unexpected animal behaviors and emotions were transformed into experimental virtues. However, to successfully translate such behaviors from the animal laboratory into the field of human psychopathology, Liddell increasingly reached beyond, and, in effect, redefined, the Pavlovian method to make it compatible and compliant with an ethological approach to the animal laboratory. We show how the resultant Behavior Farm served as a productive “hybrid” place, containing elements of experiment and observation, laboratory and field. It was through the building of close and more naturalistic relationships with animals over extended periods of time, both normal and pathological, and within and outside of the experimental space, that Liddell could understand, manage, and make useful the myriad behavioral complexities that emerged from the life histories of experimental animals, the researchers who worked with them, and their shared relationships to the wider physical and social environments. (shrink)

Enormous and significant progress has been made in the important areas of entanglement, quantum computing and harnessing energy from the vacuum, which includes a sound theoretical basis, using the Einstein-Sachs theories to develop an anti-symmetric general relativity (AGR) approach to a higher topology O(3) electrodynamics. These developments also lead to the application of the Aharonov-Bohm effect and the Yang-Mills theory to the higher topology O(3) electrodynamics, as well as a deeper understanding and appreciation of these effects and their impact on (...) modern physics. The door is now open for the further development and unification of physics, including the gravitational, electromagnetic, weak, and strong forces, using the AGR approach. (shrink)

Introduction -- Reconstructing Nīsābūrī's early education -- Nīsābūrī's early scientific thought -- Nīsābūrī's early religious thought -- Astrology motivating inductions about God's power -- Nīsābūrī's later scientific thought -- The impact of science on Nīsābūrī's religious thought -- The limits of science's influence on Nīsābūrī's religious thought -- Conclusion.

ABSTRACT In the context of the COVID-19 pandemic, leaders are facing an ethical dilemma and a tense tradeoff between employees’ health and economic performance. From the perspective of employees’ perceptions of the work situation, this study examines the way ethical leadership enhances employee creativity during the COVID-19 pandemic by using leader-member exchange and organizational ethical climate as mediators. The sample included 308 supervisor-employee pairs from 20 high-tech companies in eight provincial regions of China. Structural equation modeling was used to test (...) the proposed hypotheses. Results indicate that ethical leadership can significantly enhance employee creativity through the fully mediating roles of employees’ perceptions of leader-member exchange and organizational ethical climate. Moreover, leader-member exchange affects employee creativity directly as well as indirectly through the mediating role of organizational ethical climate. This study offers insights into the process linking ethical leadership to employee creativity and provides practical suggestions on ways of enhancing employee creativity in situations like the COVID-19 pandemic crisis. (shrink)

This volume centers on philosophical issues of the life sciences, particularly genetics and psychology, and the relevance of statistical data as the foundation for inductive reasoning in areas such as vaccination testing, population genetics, evolutionary theory, and natural selection. Also discussed is the role of psychology in defining thought processes, experiences, and behaviors and their subsequent relation to scientific discovery, and advancing knowledge of the human condition and human potential.

Economists, in stressing the prescriptive implications of their analysis, typically have ignored the potential contributions of their theorems and methodological principles to the understanding of human behavior as an end in itself. The purpose of the paper is to establish the principle, by detailed reference to the literature of economics, that the 'deductive pattern of explanation' constitutes a valid approach to the general study of human behavior. As such, it is a potentially useful method of analysis in the other social (...) sciences. Literature from the philosophy of social science bearing on the applicability of deductive theory to the study of human behavior is subjected to detailed critical analysis. (shrink)

Concise and clearly written, this volume surveys the doctrines of Plato, Aristotle, Descartes, Berkeley, Hume, and Kant, presenting major issues in metaphysics and the relationship between philosophy and science, and examining Cartesian rationalism and other theories of knowledge. It considers moral responsibilities and problems in ethics, discusses the philosophy of religion, and reviews some arguments for the existence of God. It concludes with an exploration of trends in twentieth-century philosophy, including pragmatism, analytical philosophy, logical positivism, and existentialism. An excellent introduction, (...) this volume provides the necessary perspective and critical insight to pursue further readings in philosophy, and will prove equally valuable in and out of the classroom. (shrink)

This article argues that the movement of dogs from pounds to medical laboratories played a critically important role in debates over the use of animals in science and medicine in the United States in the twentieth century, not least by drawing the scientific community into every greater engagement with bureaucratic political governance. If we are to understand the unique characteristics of the American federal legislation that emerges in the 1960s, we need to understand the long and protracted debate over the (...) use of pound animals at the local municipal and state level between antivivisectionists, humane activists, and scientific and medical researchers. We argue that the Laboratory Animal Care Act of 1966 reflects the slow evolution of a strategy that proved most successful in local conflicts, and which would characterize a “new humanitarianism”: not the regulation of experimental practices but of the care and transportation of the animals being provided to the laboratory. Our analysis is consistent with, and draws upon, scholarship which has established the productive power of public agencies and civil society on the periphery of the American state. (shrink)

Evolution is littered with polyphyletic parallelism: many roads lead to functional Romes. We propose consciousness embodies one such example, and represent it here with an equivalence class structure that factors the broad realm of necessary conditions information theoretic realizations of Baars’ global workspace model. The construction suggests many different physiological systems can support rapidly shifting, highly tunable, and even simultaneous temporary assemblages of interacting unconscious cognitive modules. The discovery implies various animal taxa exhibiting behaviors we broadly recognize as conscious are, (...) in fact, expressing different forms of the same underlying phenomenon. The variety of possibilities suggests minds today may be only a small surviving fraction of ancient evolutionary radiations – bush phylogenies of consciousness pruned by selection and chance extinction. Although few traces of the radiations may be found in the fossil record, exaptations and vestiges are scattered across the living mind. (shrink)

Pain management has improved in the past few decades. Opioid analgesics have become the mainstay in the treatment of cancer pain whilst inter-disciplinary pain management programmes are the generally accepted approach to chronic pain of non-malignant origin. Recently some pain specialists have advocated the use of opioids in the long-term management of non-cancer pain. This has raised some fundamental questions about the purpose of pain management. Is it best to opt for maximum pain relief and comfort, or should one emphasise (...) function and activity as higher priorities? Will the use of opioids create more autonomy for pain sufferers or will this add handicaps to lives which are already limited? Until more clinical outcome data are available we advocate caution in the use of opioid analgesia. Such caution can, and does, raise questions about the rights of the patient and the rights of the prescriber in a context where the facts do not point to a clear course of action. (shrink)

First published in 1993. Routledge is an imprint of Taylor & Francis, an informa company.