Background In the course of the COVID-19 pandemic, the biomedical research community’s attempt to focus the attention on fighting COVID-19, led to several challenges within the field of research ethics. However, we know little about the practical relevance of these challenges for Research Ethics Committees. Methods We conducted a qualitative survey across all 52 German RECs on the challenges and potential solutions with reviewing proposals for COVID-19 studies. We de-identified the answers and applied thematic text analysis for the extraction and (...) synthesis of challenges and potential solutions that we grouped under established principles for clinical research ethics. Results We received an overall response rate of 42%. The 22 responding RECs reported that they had assessed a total of 441 study proposals on COVID-19 until 21 April 2020. For the review of these proposals the RECs indicated a broad spectrum of challenges regarding social value, scientific validity, favourable risk–benefit ratio, informed consent, independent review, fair selection of trial participants, and respect for study participants. Mentioned solutions ranged from improved local/national coordination, over guidance on modified consent procedures, to priority setting across clinical studies. Conclusions RECs are facing a broad spectrum of pressing challenges in reviewing COVID-19 studies. Some challenges for consent procedures are well known from research in intensive care settings but are further aggravated by infection measures. Other challenges such as reviewing several clinical studies at the same time that potentially compete for the recruitment of in-house COVID-19 patients are unique to the current situation. For some of the challenges the proposed solutions in our survey could relatively easy be translated into practice. Others need further conceptual and empirical research. Our findings together with the increasing body of literature on COVID-19 research ethics, and further stakeholder engagement should inform the development of hands-on guidance for researchers, funders, RECs, and further oversight bodies. (shrink)

1. T. Antike Philosophie -- 2. T. Christliche Philosophie.

A prominent figure in the Twin Cities art scene, Chris Faust marks the essence of the changing Midwestern landscape by documenting common scenes in an uncommon way. Known for his spectacular panoramic work, Faust is also increasingly admired for his unique night photographs, where he quietly unveils a world we never noticed was there and when the darkest hours evoke a mood of mystery and surrealism. The palette of light and shadow heightens our senses by revealing the stillness (...) and ambiguities of the landscape. Nocturnes, a beautiful collection of more than seventy tritone photographs, is a visual record of our world as few ever see it: during the nighttime hours. Emphasizing the passage of time as well as the necessity for change, the images reflect our disappearing rural terrain, abandoned urban streets, and aging industrial spaces, recalling aspects of our culture that are quickly fading into the past. With an affinity for certain old-world practices and tools, Faust works just with ambient light and uses no digital or electronic technology—only classic darkroom processing—allowing all the subtle textures and tones to emerge in his work. Faust’s photographs of the Midwest are shot in a panoramic format with wide, detailed images—spectacular in both their artistry and documentary impact. Chris Faust, a resident of St. Paul, is one of Minnesota’s finest photographers. His award-winning images are widely collected and exhibited throughout the region and the country. Joan Rothfuss is a writer and art historian who was curator of the Walker Art Center for more than seventeen years. She was coeditor of the Walker collection catalogue Bits & Pieces Put Together to Present a Semblance of a Whole. (shrink)

edited by Tuija Takala and Matti Häyry, welcomes contributions on the conceptual and theoretical dimensions of bioethics.

This book examines the history of violence and terrorism while showing how fragmentation is accelerating to such proportions that it now threatens to annihilate all of humanity. Though no different today than it was centuries ago, violence is now aided by modern technology and its promotion of destructive weapons.

The study of human judgment and its limitations is essential to an understanding of the processes involved in the acquisition of scientific knowledge. With that end in mind, David Faust has made the first comprehensive attempt to apply recent research on.

More powerful methods for studying and integrating the historical track record of scientific episodes and scientific judgment, or what Faust and Meehl describe as a program of meta‐science and meta‐scientific studies, can supplement and extend more commonly used case study methods. We describe the basic premises of meta‐science, overview methodological considerations, and provide examples of meta‐scientific studies. Meta‐science can help to clarify or resolve long‐standing questions in the history and philosophy of science and provide practical help to the working (...) scientist. (shrink)

Using Evidence Logic (EL), a logic which is conceptually to Classical Logic and which is equipped with both gradational confirmatory predications and gradational refutatory predications, further investigation of some of the persistent problematic aspects of negation is facilitated. This perspective helps to illuminate distinction of “absence of evidence”, and may help further understanding of the semantics of negation.

The “Assyrian Century,” the period of Assyrian rule in the Levant, is usually regarded as an era of prosperity and economic progress. As far as the southern Levant is concerned, this reconstruction more or less reflects the reality on the southern edge of the region—in the areas of Philistia, Judah, and Edom. But what was the situation in the northern part of the country, in the territories of the former kingdom of Israel and adjacent territories, regions that had become Assyrian (...) provinces? It is the aim of this paper to scrutinize the archaeological data from these regions in order to shed light on the settlement and demographic reality in those provinces, and furthermore to reassess Assyrian policy in the west. After summarizing previous research, the article will present the available archaeological data, which will then be compared with that from the southern part of the country in order to enable a reexamination of the Assyrian empire’s policy in the west. (shrink)

By using preimplantation haplotype diagnosis, prospective parents are able to select embryos to implant through in vitro fertilization. If we knew that the naturally-occurring (but theoretical) MoralKinder (MK+) haplotype would predispose individuals to a higher level of morality than average, is it permissible or obligatory to select for the MK+ haplotype? I.e., is it moral to select for morality? This paper explores the various potential issues that could arise from genetic moral enhancement.

This article argues that, despite their distance across the colonial divide, a creolizing reading of Frantz Fanon and Paul Ricœur can yield valuable insights into decoloniality. Tracing their shared philosophical concerns with embodied phenomenology, social ontology and recognition, I argue that their respective accounts of sociogeny and hermeneutics can be productively read together as describing a shared end of mutual recognition untainted by racism or coloniality – a ‘new skin’ for humanity, as Fanon describes it. More specifically, Fanon contributes to (...) Ricœur an understanding of how divergences in social location can be overcome through liberatory action that posits a new logic of sociality; likewise, Ricœur provides Fanon with an account of how liberatory horizons are produced through this praxis, based on the imaginative connection between ideology and utopia. This article concludes by arguing that these congruent methodological and normative concerns can be read together to concretize – and potentially actualize – the utopic end of liberatory struggle in mutual recognition through fashioning this new skin. (shrink)

Are restrictive measures and duties to care ethically reasonably acceptable to faith-based organizations? This study describes the perceptions of individually interviewed spiritual leaders of the disease control measures used during the recent SARS outbreak in Toronto. Four central themes were identified: the relationship between religious obligation and civic responsibilities; the role of faith-based organizations in supporting public health restrictive measures; the reciprocal obligations of public health and religious communities during restrictions; and justifiable limits to duties to care. We conclude that, (...) within certain constraints, spiritual leaders find restrictive measures ethically reasonable and that spiritual leaders can play an important role during pandemic and epidemic control planning. Public health officials should therefore include them in the early and ongoing deliberations of the criteria and logistics for implementation during public health emergencies. (shrink)

In his famous essay "The Ethics of Belief," William K. Clifford claimed "it is wrong always, everywhere, and for anyone, to believe anything upon insufficient evidence." ). One might claim that a corollary to Clifford's Law is that it is wrong, always, everywhere, and for anyone, to withhold belief when faced with sufficient evidence. Seeming to operate on this principle, many religious philosophers—from St. Anselm to Alvin Plantinga—have claimed that non-believers are psychologically or cognitively deficient if they refuse to believe (...) in the existence of God, when presented with evidence for His existence in the form of relevant experience or religious arguments that are prima facie unassailable. Similarly, many atheists fail to see how believers can confront the problem of evil and still assert their belief in a benevolent, omnipotent, and omniscient Creator. In this paper, I propose to explain why religious arguments so often fail to persuade. In doing so, I first offer an account of persuasion and then apply it to religious arguments. I go on to argue that at least some religious arguments commit a form of question-begging, which I call "begging the doxastic question." An argument begs the doxastic question, on my account, when a subject would find the argument persuasive only if she antecedently believes the argument's conclusion. This form of question begging is not, strictly speaking, a case of circularity and thus, is not a fallacy; rather, it would explain why one coming to the argument would fail to be persuaded by it unless he already accepted its conclusion. This has the effect, when applied to religious argumentation, that religious arguments are rarely persuasive, which raises the further question: what good are religious arguments? I end by suggesting some non-persuasive functions of religious argument. Finally, I suggest that a full understanding of religious argumentation should give evidentialists pause, for religious beliefs look less like belief states that are sensitive to evidentiary states and more like framework principles or fundamental commitments. (shrink)

Explorationism (see www.bu.edu/wcp/Papers/Logi/LogiFaus.htm, WCP XX, “Conflict without Contradiction”) is a perspective concerning human knowledge: as yet, our ignorance of the Real World remains great. With this perspective, all our knowledge is so far only partial and tentative. Evidence Logic (EL) (see “The Concept of Evidence”, INTER. JOURNAL OF INTELLIGENT SYSTEMS 15 (2000), 477‐493) provides an example of a reasonable Base Logic for Explorationism:EL provides machinery for the representation and processing of gradational evidential predications. Syntactically, for any evidence level e, for (...) a proposition symbol P, Pc:e asserts that there is level e confirmatory evidence regarding P, while Pr:e asserts level e refutatory evidence (n‐ary predications, for n>0, are handled similarly). Semantically, EL has similarly enriched model spaces. The Boolean sentence algebras of the variety of EL languages, varying across stipulated families of predicate and functions symbols, have been analyzed, and EL is sound and complete. Belief Systems, we will argue, are all unnecessary: in science, as well as in all broader domains of human relations and activity, it is always sufficient to have simply commitments, which entail no assertion of Truth but rather simply entail agreed‐upon consequent actions. (Agent A believes a sentence S if A asserts S is True although A does not know (have absolute evidence) that S is True.) We will further seek to explore ways in which such a perspective may help in engendering more enhanced discourse, less absolutist and shrill advocacy and violence, and more rationality, in the Global Village of the new century. (shrink)

When we know who we truly are, rather than who we take ourselves to be, we will realize that we are indeed the hero of our story and that we need not look to others or the world to find our heart's desire.

Sunnybrook Health Sciences Centre, Toronto and University of Toronto Ross E. G. Upshur * Sunnybrook Health Sciences Centre, Joint Centre for Bioethics University of Toronto, Toronto * Corresponding author: Ross E. G. Upshur, Primary Care Research Unit, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, #E-349, Toronto, Ontario, Canada M4N 3M5. Tel.: 416-480-4753; Fax: 416-480-4536; Email: ross.upshur{at}sunnybrook.ca ' + u + '@' + d + ' '//--> Abstract Are restrictive measures and duties to care ethically reasonably acceptable to faith-based organizations? This (...) study describes the perceptions of individually interviewed spiritual leaders of the disease control measures used during the recent SARS outbreak in Toronto. Four central themes were identified: the relationship between religious obligation and civic responsibilities; the role of faith-based organizations in supporting public health restrictive measures; the reciprocal obligations of public health and religious communities during restrictions; and justifiable limits to duties to care. We conclude that, within certain constraints, spiritual leaders find restrictive measures ethically reasonable and that spiritual leaders can play an important role during pandemic and epidemic control planning. Public health officials should therefore include them in the early and ongoing deliberations of the criteria and logistics for implementation during public health emergencies. CiteULike Connotea Del.icio.us What's this? (shrink)

When we reframe design through a discourse, designing on a meta level, we are actually designing design, as we are giving design a different meaning, changing frame to include or exclude what we do or don't consider as a part of the field. Therefore we need to frame at first what we understand in speaking about design. And it is far more complex to speak about media design, since it triggers the idea of designing media. Marshall McLuhan's thoughts on media (...) will help to explore what a media designer actually does; what he designs. However, if the digital media comes into place, the new medium, the digital medium, suddenly is the major carrier of all of society's messages. How does it change the designer's work, and does it require a different designer. (shrink)

Collaboration must be based on careful representation and communication of each stakeholder’s knowledge. Using a foundational logical and epistemological point of view, we explore how such representation and communication can be accomplished. We tentatively conclude, based on careful delineation of logical technicalities necessarily involved in such representation and communication, that currently a complete representation is not possible. This inference, if correct, is discouraging. However, we suggest two actions. First, we can strive to make stakeholders more aware of the incompleteness of (...) knowledge representations. Second, moderating one’s certainty of “Truth” should increase each stakeholder’s humility, thereby promoting the efficacy of collaborations. (shrink)