A common account sees the human genome sequencing project of the 1990s as a “natural outgrowth” of the deciphering of the double helical structure of DNA in the 1950s. The essay aims to complicate this neat narrative by putting the spotlight on the field of human chromosome research that flourished at the same time as molecular biology. It suggests that we need to consider both endeavors – the human cytogeneticists who collected samples and looked down the microscope and the molecular (...) biologists who probed the molecular mechanisms of gene function – to understand the rise of the human genome sequencing project and the current genomic practices. In particular, it proposes that what has often been described as the “molecularization” of cytogenetics could equally well be viewed as the turn of molecular biologists to human and medical genetics – a field long occupied by cytogeneticists. These considerations also have implications for the archives that are constructed for future historians and policy makers. (shrink)

Berichte zur Wissenschaftsgeschichte, Volume 45, Issue 3, Page 462-467, September 2022.

This article discusses how the persistence of child labor, especially in Brazil and the United States of America, constitutes a current facet of neo-colonialism. Cultivated as an educational and dignifying activity, exploited child labor persists and is naturalized. Schools, religions, and the legislation contribute to making the working class come to love and naturalize what in the past was understood as torture and punishment, thus jointly acting as a fundamental means of forming a new cultural form: the love of work. (...) Initially, the article discusses how the culture of work is historically founded and then argues against the idealist and postmodern explanations that naturalize it. The argument is based on the understanding that culture has a material basis and is linked to the production and social reproduction of life. Data from the empirical research on child labor in tobacco farming in Brazil and the USA reveal the persistence of the problem among Latino children and families. We conclude with the need to found a new culture for contemporary society, based on other social and economic relations, which allows the working class to free itself from what dominates and exploits it. (shrink)

As possibilidades de diálogo pedagógico entre os campos da Educação Ambiental e Formação Humana nos cursos de Educação Física é objeto deste estudo. Buscando revisar e evidenciar os princípios e objetivos construídos historicamente da Educação Ambiental e a atual realidade da formação de professores, identificando os limites e possibilidades para a construção de uma proposta crítica pedagógica que altera a lógica na Formação de Professores em Educação Física a partir do tripé ensino, pesquisa e extensão e a Educação Ambiental.The possibilities (...) pedagogical of the dialogue between the fields of Human Environmental Education and Training courses in Physical Education is an object of this study. The objective is review and clear the principles and objectives of environmental education, identifying the limits and possibilities for building critical pedagogical proposal amending the logic in the courses of the physical education from the triad education, research and outreach and environmental education. (shrink)

In this essay, I propose a comprehension of the meaning of politics based on Martin Heidegger’s thinking. I will develop the idea of the political as essential displacement of humanity. This notion will be achieved precisely by understanding the Heideggerian interpretation of Polis [πόλις] as the historical place i.e. the “site of history” [Geschichtesstätte]. In order to establish my argument, I will focus not only on explicit references to the concept of Polis in his literature, but also on a brief (...) analysis of two key concepts presented in his work in the late 1930s: machination [Machenschaft] and lived-experience [Er-lebnis]. It is through these concepts, but also how, through them, a technicity and history are related, that I will delineate a context for the meaning of politics as essential displacement of humanity, which will thereby conform to the basic character of the techno-political being. Nevertheless, a reflection upon the meaning of politics leading to the characterisation of the human as a techno-political being will show itself as the question about the place of the philosopher, a way to put philosophy itself in question. (shrink)

Carla CANULLO Paco Editorial, Trad. Íris Fátima da Silva Uribe e Luis Uribe Miranda 2021 404 páginas. Jundiaí São, Brasil ISBN: 978-85-462-1999-5.

Resumo: A Lei 10.639/03 depositou diante do universo docente o desafio de propalar o Ensino de História e Cultura Afro-brasileira e Africana, numa perspectiva contrária a visão eurocêntrica predominante até então. Cabia às Secretarias de Educação subsidiar as escolas, o que exigia formação de equipes aptas ao processo, bem como compreensão da lei e mudanças nas concepções de currículo e práxis dos/as educadores/as. O presente artigo vem apresentar justamente a caminhada da Secretaria Municipal de Educação no Município de Manaus/SEMED/MANAUS quanto (...) a inserção dos temas nas documentações. Apresenta a construção de uma Proposta Pedagógica Curricular/PPC, alinhada a lei. Contudo, traz a reflexão de que a mudança realizada na PPC é um avanço, mas não é garantia de disseminação de atitudes e conhecimentos necessários para a formação integral antirracista dos estudantes. A SEMED/MANAUS, reconhece que é necessário a mudança de postura dos educadores, por isso desde a implantação da referida PPC, realiza oficinas, formações e demais ações pertinentes a temática. Dessa forma conjectura-se que o trabalho dos/as professores tem caminhado na perspectiva da formação integral antirracista dos estudantes. Palavras chaves: Lei 10.639/03. Escola. Currículo. Educação integral antirracista. (shrink)

Violence -- Poliltical philosophy -- Critical theory -- Science and arts in international relations -- Psyche -- Aesthetics -- Tolstoi's War and peace.

Cette étude analyse comment Kelsen, pour libérer le droit et la démocratie des traces de ce qu'il appelle les hypostases collectives ou la mythologie de l'âme collective, prend position face aux grandes théories de la sociologie et de la psychologie sociale de son temps. D'abord, il s'agira de montrer comment Kelsen critique les métaphores de l'âme collective ; ensuite, de montrer comment la pensée kelsénienne sur le droit et la démocratie essaie d'échapper aux problèmes liés à la métaphore de l'âme (...) collective. Cela peut laisser entrevoir quelques points communs entre la théorie de Kelsen et les théories contemporaines sur le droit et la démocratie libérées des prémisses de l'idée d'une communauté homogène. The aim of this essay is to analyse how Kelsen criticises the major theories of sociology and social psychology of his time in order to liberate law and democracy from what he calls collective hypostasis or the mythology of the "collective soul". The first part investigates how Kelsen criticises the metaphors of the collective soul. The second part addresses how Kelsen built a theory of law and democracy that sought to escape from problems correlated to the metaphors of the collective soul. The results enable the reader to glimpse some common points between Kelsen's ideas and contemporary projects to elaborate a theory of law and democracy released from the premises implicated by the idea of a uniform community. (shrink)

BackgroundAlthough a large number of clinical trials on interventions demonstrating efficacy (or lack thereof) are conducted annually, much of this evidence is not accessible to scientists and clinicians.ObjectivesWe aimed to determine the publication rate of posttraumatic stress disorder (PTSD) trials that have been registered in clinical trial registries, and the factors associated with publication.MethodsTrials, completed on January 15, 2015, were identified via the US National Institutes of Health clinical trials registry, the European Union Clinical Trials Register and the WHO International (...) Clinical Trials Registry Platform. A systematic search for publications (published by the end of March 2018) related to each of the registered trials were then performed.ResultsFour hundred and thirty-eight of 1982 potentially eligible trials were included. Only 34% of interventional trials were registered prior to initiation, 9% were registered within 2 months of starting and 20% after trial completion. Of the 438 included trials, 72% had generated peer-reviewed publications, while an additional 7% had disseminated results in some other form (such as on the trial database), 26 months after trial completion. Randomisation of a trial was the only factor individually associated with publication, in logistic regression analysis (p < 0.001). Intervention type, university as sponsor and study registration prior to completion were factors that influenced the time to publication, using Cox regression (p < 0.001).ConclusionsThis study underscores the importance of timely and accurate publication and dissemination of trial results, in order to avoid the potential waste of resources and to ensure research integrity and patient safety. We suggest that authors and journal editors adhere to conditions set out by the International Committee of Medical Journal Editors and that more diligent data sharing is encouraged through prospective trial registration and trial reporting websites. (shrink)

Predicates involved in language and reasoning are claimed to radically differ from categories applied to objects. Human predicates are the cognitive result of a contrast between perceived objects. Object recognition alone cannot generate such operations as modification and explicit negation. The mechanism studied by Hurford constitutes at best an evolutionary prerequisite of human predication ability.

In the remainder of this article, we will disarm an important motivation for epistemic contextualism and interest-relative invariantism. We will accomplish this by presenting a stringent test of whether there is a stakes effect on ordinary knowledge ascription. Having shown that, even on a stringent way of testing, stakes fail to impact ordinary knowledge ascription, we will conclude that we should take another look at classical invariantism. Here is how we will proceed. Section 1 lays out some limitations of previous (...) research on stakes. Section 2 presents our study and concludes that there is little evidence for a substantial stakes effect. Section 3 responds to objections. The conclusion clears the way for classical invariantism. (shrink)

This article examines whether people share the Gettier intuition (viz. that someone who has a true justified belief that p may nonetheless fail to know that p) in 24 sites, located in 23 countries (counting Hong Kong as a distinct country) and across 17 languages. We also consider the possible influence of gender and personality on this intuition with a very large sample size. Finally, we examine whether the Gettier intuition varies across people as a function of their disposition to (...) engage in “reflective” thinking. (shrink)

For many years, scientific heritage has received attention from multiple actors from different spheres of activity—archives, museums, scientific institutions. Beyond the heterogeneity revealed when examining the place of scientific heritage in different places, an authentic patrimonial configuration emerges and takes the form of a nebula of claims and of accomplishments that result, in some cases, in institutional and political recognition at the national level, in various country all around the world. At the international level, the creation of the international committee (...) dedicated to University Museums and Collections within the International Council of Museums certainly testified from this raising interest in academic heritage and the existence of a specific community concern with it.This article presents numerous initiatives for the preservation of scientific heritage in France, with the goal of analysing the relationship scientists have with their heritage. We argue that scientific communities have a special relationship with heritage, which is characterized by a number of ambiguities. We show that such ambivalences allow analysis of identity, discipline, professional, and social issues operative in defining heritage and being redefined by heritage. To explore these dimensions, we have chosen to present three different case studies. The first traces the institutional uses of heritage by a scientific institution, the Commissariat à l’énergie atomique, through the transformation of the first French atomic reactor into a museum. The second example describes the initiatives of French astronomers from the mid-1990s to construct a national programme for the protection of astronomy heritage. Lastly, we recount the case of universities, with the example of the Université de Strasbourg. (shrink)

Philosophers have long debated whether, if determinism is true, we should hold people morally responsible for their actions since in a deterministic universe, people are arguably not the ultimate source of their actions nor could they have done otherwise if initial conditions and the laws of nature are held fixed. To reveal how non-philosophers ordinarily reason about the conditions for free will, we conducted a cross-cultural and cross-linguistic survey (N = 5,268) spanning twenty countries and sixteen languages. Overall, participants tended (...) to ascribe moral responsibility whether the perpetrator lacked sourcehood or alternate possibilities. However, for American, European, and Middle Eastern participants, being the ultimate source of one’s actions promoted perceptions of free will and control as well as ascriptions of blame and punishment. By contrast, being the source of one’s actions was not particularly salient to Asian participants. Finally, across cultures, participants exhibiting greater cognitive reflection were more likely to view free will as incompatible with causal determinism. We discuss these findings in light of documented cultural differences in the tendency toward dispositional versus situational attributions. (shrink)

Since at least Hume and Kant, philosophers working on the nature of aesthetic judgment have generally agreed that common sense does not treat aesthetic judgments in the same way as typical expressions of subjective preferences—rather, it endows them with intersubjective validity, the property of being right or wrong regardless of disagreement. Moreover, this apparent intersubjective validity has been taken to constitute one of the main explananda for philosophical accounts of aesthetic judgment. But is it really the case that most people (...) spontaneously treat aesthetic judgments as having intersubjective validity? In this paper, we report the results of a cross‐cultural study with over 2,000 respondents spanning 19 countries. Despite significant geographical variations, these results suggest that most people do not treat their own aesthetic judgments as having intersubjective validity. We conclude by discussing the implications of our findings for theories of aesthetic judgment and the purpose of aesthetics in general. (shrink)

This article examines whether people share the Gettier intuition (viz. that someone who has a true justified belief that p may nonetheless fail to know that p) in 24 sites, located in 23 countries (counting Hong-Kong as a distinct country) and across 17 languages. We also consider the possible influence of gender and personality on this intuition with a very large sample size. Finally, we examine whether the Gettier intuition varies across people as a function of their disposition to engage (...) in “reflective” thinking. (shrink)

Microstudies and big picture accounts are often counterposed. This paper investigates the supposed dichotomy between the two historiographical approaches. In particular it investigates how the discussions are reflected in the historiography of molecular biology and the special questions posed by the disciplinary context. Taking inspiration from the microhistory tradition as exemplified by the works of Carlo Ginzburg, Jacques Revel, and David Sabean among others, the paper highlights the heuristic value of microstudies to reconstruct the multiple contexts that link apparently small (...) events with broader structures. In a parallel fashion, the paper argues for using microstudies to open up the history of molecular biology to other fields of study and thus moving beyond the confines of the disciplinary framework. Such an approach does not dismiss the search for big pictures. Yet rather than opposing big pictures to microstudies, it sees microstudies as a valid way to gain new and broad vistas. (shrink)

Does the Ship of Theseus present a genuine puzzle about persistence due to conflicting intuitions based on “continuity of form” and “continuity of matter” pulling in opposite directions? Philosophers are divided. Some claim that it presents a genuine puzzle but disagree over whether there is a solution. Others claim that there is no puzzle at all since the case has an obvious solution. To assess these proposals, we conducted a cross-cultural study involving nearly 3,000 people across twenty-two countries, speaking eighteen (...) different languages. Our results speak against the proposal that there is no puzzle at all and against the proposal that there is a puzzle but one that has no solution. Our results suggest that there are two criteria—“continuity of form” and “continuity of matter”— that constitute our concept of persistence and these two criteria receive different weightings in settling matters concerning persistence. (shrink)

Is behavioral integration (i.e., which occurs when a subjects assertion that p matches her non-verbal behavior) a necessary feature of belief in folk psychology? Our data from nearly 6,000 people across twenty-six samples, spanning twenty-two countries suggests that it is not. Given the surprising cross-cultural robustness of our findings, we suggest that the types of evidence for the ascription of a belief are, at least in some circumstances, lexicographically ordered: assertions are first taken into account, and when an agent sincerely (...) asserts that p, non-linguistic behavioral evidence is disregarded. In light of this, we take ourselves to have discovered a universal principle governing the ascription of beliefs in folk psychology. (shrink)

In this brief essay, we combine biological, historical, philosophical and anthropological perspectives to ask anew the question about the nature of the virus. How should we understand Sars-CoV-2 and why does it matter? The argument we present is that the virus undermines any neat distinction between the natural and the human-made, the biological and the social. Rather, to understand the virus and the pandemic we need to understand both as intimately connected to our own social and historical condition. What started (...) as a reflection on the nature of the virus thus turns into a reflection on the human condition as refracted in this pandemic or an anthropology of the virus. (shrink)

ABSTRACT Monoclonal antibodies played a key role in the development of the biotechnology industry of the 1980s and 1990s. Investments in the sector and commercial returns have rivaled those of recombinant DNA technologies. Although the monoclonal antibody technology was first developed in Britain, the first patents were taken out by American scientists. During the first Thatcher government in Britain, blame for the missed opportunity fell on the scientists involved as well as on the National Research and Development Corporation, which had (...) been put in place after World War II to avoid a repeat of the penicillin story, when patent rights were not sought. Instead of apportioning the blame, this essay suggests that despite past experiences and despite the new channels that were in place, Britain was not in a “patent culture” in the 1970s. It traces the long and painful process that made a commercial attitude among publicly funded British research scientists and in a civil service institution like the Medical Research Council both possible and desirable. In this process the meaning of the term “public science” also changed dramatically. (shrink)

The history of physical anthropology has most often been situated and studied in the context of specific colonial powers and nation states. At the same time, the study of human variation had as its scope to study human evolution on a global scale. It thus necessarily included transnational border crossings and scholarly exchanges of specimen collections that allowed researchers to study migration and differentiation patterns on a large scale. In addition, scientists working in a national context often sought international approval (...) to validate their findings and gain national standing. The set of essays collected in this special issue takes this tension between national, transnational, and global impulses in the... (shrink)