Early versions of satellite and radiosonde datasets suggested that the tropical surface had warmed more than the troposphere, while climate models consistently showed tropospheric amplification of surface warming in response to human-caused increases in greenhouse gases. We revisit such comparisons here using new observational estimates of surface and tropospheric temperature changes. We find that there is no longer a serious discrepancy between modeled and observed trends in the tropics. Our results contradict a recent claim that all simulated temperature trends in (...) the tropical troposphere are inconsistent with observations. This claim was based on the use of older radiosonde and satellite datasets and on two methodological errors: the neglect of observational trend uncertainties introduced by interannual climate variability and application of an inappropriate statistical “consistency test”.This emerging reconciliation of models and observations has two primary explanations. First, because of changes in the treatment of buoy and satellite information, new surface temperature datasets yield slightly reduced tropical warming relative to earlier versions. Second, recently developed satellite and radiosonde datasets now show larger warming of the tropical lower troposphere. In the case of a new satellite dataset from remote sensing systems, enhancedRSS warming is due to an improved procedure of adjusting for inter-satellite biases. When the RSS-derived tropospheric temperature trend is compared with four different observed estimates of surface temperature change, the surface warming is invariably amplified in the tropical troposphere, consistent with model results. Even if we use data from a second satellite dataset with smaller tropospheric warming than in remote sensing systems RSS, observed tropical lapse rates are not significantly different from those in all model simulations.Our results contradict a recent claim that all simulated temperature trends in the tropical troposphere and in tropical lapse rates are inconsistent with observations. This claim was based on the use of older radiosonde and satellite datasets and on two methodological errors: the neglect of observational trend uncertainties introduced by interannual climate variability and application of an inappropriate statistical “consistency test”. (shrink)

The aim of the present investigation was to describe and to classify significant ethical problems encountered by the members of the staff during the daily clinical work at a hospital medical department. A set of definitions was prepared for the purpose, including the definition of a 'significant ethical problem'. During a three month period 426 inpatients and 173 outpatients were admitted. Significant ethical problems were encountered during the management of 106 in-patients (25 per cent) and 9 out-patients (5 per cent). (...) No significant difference was found between the frequency of ethical problems in female and male patients, but a positive correlation was noted between the number of problems and the patients' age. The problem types were classified according to a problem list. The results of this investigation suggest that greater attention must be paid to discussions about ethical problems among doctors and other categories of health personnel and that, among others, medical students ought to be taught the analysis of ethical problems. (shrink)

Gesellschaftliche Veränderungen in grossem Massstab, von der Pluralisierung der Gesellschaft, der Digitalisierung, die als Vierte Kulturtechnik bezeichnet wird, bis hin zur Widerfahrnis von Kontingenzen wie Armut und Flüchtlingsströmen oder Umweltkatastrophen, stellen die Verantwortungsfähigkeit des Menschen vor neue Herausforderungen. Es wird dabei deutlich: Humanität und Vernunft, Würde und Freiheit verdanken ihren Gehalt und ihre Gestalt einem die Vernunft selbst übersteigenden Transzendenten, in dem die Vernunft je und je ihres eigenen Grundes ansichtig werden kann. Dass dieses Verhältnis zwischen Vernunft und ihrem transzendenten (...) Grund alle Wissens- und Lebensbereiche durchdringt, zeigen die interdisziplinären Beiträge dieses Bandes, die Fragen der Weltentstehung und Anthropologie, der Logik und Mystik, des Glaubens und des Gottesbildes, des Sinns und der Religion, der Gottesdienstpraxis und der Architektur behandeln. (shrink)

Background: Emergency exception to informed consent regulation was introduced to provide a venue to perform research on subjects in emergency situations before obtaining informed consent. For a study to proceed, institutional review boards need to determine if the regulations have been met.Aim: To determine IRB members’ experience reviewing research protocols using emergency exception to informed consent.Methods: This qualitative research used semistructured telephone interviews of 10 selected IRB members from around the US in the fall of 2003. IRB members were chosen (...) as little is known about their views of exception to consent, and part of their mandate is the protection of human subjects in research. Interview questions focused on the length of review process, ethical and legal considerations, training provided to IRB members on the regulations, and experience using community consultation and notification. Content analysis was performed on the transcripts of interviews. To ensure validity, data analysis was performed by individuals with varying backgrounds: three emergency physicians, an IRB member and a layperson.Results: Respondents noted that: emergency exception to informed consent studies require lengthy review; community consultation and notification regulations are vague and hard to implement; current regulations, if applied correctly, protect human subjects; legal counsel is an important aspect of reviewing exception to informed-consent protocols; and IRB members have had little or no formal training in these regulations, but are able to access materials needed to review such protocols.Conclusions: This preliminary study suggests that IRB members find emergency exception to informed consent studies take longer to review than other protocols, and that community consultation and community notification are the most difficult aspect of the regulations with which to comply but that they adequately protect human subjects. (shrink)

Have you been surprised by the recent development and diffusion of generative artificial intelligence (AI)? Many institutions of civil society have been caught off guard, which provides them with motivation to think ahead. And as many new plausible pathways of socio-technical development are opening up, a growing interest in technology ethics that addresses our corresponding moral uncertainties is warranted. In Sven Nyholm’s words, “[t]he field of technology ethics is absolutely exploding at the moment” (p. 262), and so the publication of (...) his introduction to the topic is well timed. (shrink)

Mark Coeckelbergh starts his book with a very powerful picture based on a real incident: On the 9th of January 2020, Robert Williams was wrongfully arrested by Detroit police officers in front of his two young daughters, wife and neighbors. For 18 hours the police would not disclose the grounds for his arrest (American Civil Liberties Union 2020; Hill 2020). The decision to arrest him was primarily based on a facial detection algorithm which matched Mr. Williams’ driving license photo with (...) the picture of a man who was suspected of watch theft two years earlier. Not only did the computer ‘get it wrong’ as one of the detectives said, when Mr. Williams made them aware that the picture of the suspect obviously wasn’t resembling him, the probably unreliable algorithm very likely contributed to racial discrimination (Hill 2020). It is well documented that many available facial detection algorithms at this time had significant problems (e.g. a comparably high false positive rate) with respect to black persons, like Mr. Williams (NIST 2019). Multiple causes may exist, such as unbalanced training datasets and insufficient optimization. Coeckelbergh compares the disturbing case of Mr. Williams with a political interpretation of Franz Kafka’s The Trial, where the protagonist, Josef K., is accused of an unspecified crime by an opaque, oppressive and absurd bureaucracy: “In the 21st-century United States, Josef K. is black and is falsely accused by an algorithm, without explanation” (p. 2). (shrink)

Existential-Ontologie und historischer Materialismus bei Herbert Marcuse, von A. Schmidt.--Das Ganze und das ganz Andere; zur Kritik der reinen revolutionären Transzendenz, von W.F. Haug.--Technik und Eindimensionalität; eine Version der Technokratiethese? Von C. Offe.--Technologische Rationalität und spätkapitalistische ökonomie, von J. Bergmann.--Die geschichtliche Dimension des Realitätsprinzips, von H. Berndt und R. Reiche.--Marcuse and the New Left in America, by P. Breines.--Ausgewählte Bibliographie der Schriften Herbert Marcuses (p. 155-[161]).

Russell writes with wit, candor, and uncommon honesty about his Victorian childhood, his painful adolescence, and his extracurricular amorous conquests. On the credit side, it must be said that it offers a remarkable insight into the development of a remarkable man. But for the benefit of those with more than a casual interest in the philosopher named Bertrand Russell, it should be mentioned that this book suffers from chronic intellectual malnutrition. Not that there isn't a lot of name-dropping and folksy (...) correspondence between the intellectual giants of the early twentieth century. There is a perfectly mad letter from Georg Cantor, who refers to Kant as "this abominable mummy"; and a perfectly charming one from Norbert Weiner's father, who, by way of introduction, states that his son has studied philosophy under "professors Royce, Perry, Palmer, Munsterberg, Schmidt, Holt, etc." In a delicious jest, Russell adds as a footnote, "Nevertheless he turned out well." There is, however, nothing substantial about philosophy in this book. At its close, Russell had completed Principia. He had returned to Cambridge already a most important figure in philosophy and mathematics. But there is no real discussion of the ideas which led up to and leavened this period in Russell's life. There is instead the dreary story of Whitehead's financial troubles. One hopes that a proper sense of the importance of things will be restored in future volumes of Russell's autobiography.—H. P. K. (shrink)

The study of the republican Roman Senate was revolutionized by Professor Broughton's Magistrates, and to a lesser extent more recently by Professor Lily Ross Taylor's Voting Districts of the Roman Republic. Naturally, neither of these two great works rounded up all the available evidence without exception, and a considerable amount of mopping-up has been carried out. More remains to be done, however, and this article aims at providing some further information on republican senators, their tribes, and their origins, as an (...) addendum to M.R.R. and its Supplement, and the prosopogra- phical chapter of Professor Taylor's book. (shrink)

Background Biobank participants often do not understand much of the information they are provided as part of the informed consent process, despite numerous attempts at simplifying consent forms and improving their readability. We report the first assessment of biobank enrollees’ comprehension under an "integrated consent” process, where patients were asked to enroll in a research biobank as part of their normal healthcare experience. A number of healthcare systems have implemented similar integrated consent processes for biobanking, but it is unknown how (...) much patients understand after enrolling under these conditions. Methods: We recruited patients who enrolled in a biobank while in a healthcare setting when receiving ordinary care. We assessed knowledge of consent materials using 11 true/false questions drawn from a well-known biobank knowledge test. After reviewing the results from 114 participants, we revised the consent form and repeated the knowledge assessment with 144 different participants. Results: Participants scored poorly on the knowledge test in both rounds, with no significant differences in overall scores or individual items between the rounds. In Phase 1, participants answered 53% of the questions correctly, 25% incorrectly, and 22% “I don’t know.” In Phase 2, participants answered 53% of questions correctly, 24% incorrectly, and 23% “I don’t know.” Participants scored particularly poorly on questions about data sharing and accessing medical records. Conclusions: Enrollees under an integrated consent model had significant misunderstandings that persisted despite an attempt to improve information specifically about those topics in a consent form. These results raise challenges for current approaches that attribute misunderstanding to overly complex consent forms. They also suggest that the pressures of the clinic may compound other problems with patient understanding of biobank consent. As health systems increasingly blend research and care, they may need to rethink their approach to educating patients about participation in a biobank. (shrink)

Exegesis of the philosophy of Madhva, 13th century founder of the Dvaita (dualistic) school of Vedanta.

The question of form and content is one of the fundamental questions of esthetics and the theory of art. However, it remains unresolved in many respects. Certain of its aspects still have not been investigated, and others have been treated only very sketchily.

Sisenna Historiarum lib. iii: Lucium Memmium, socerum Gai Scriboni, tribunum plebis, quern Marci Livi consiliarium fuisse callebant et tune Gurionis oratorem … . Erat Hortensius in bello primo anno miles, altero tribunus militum, Sulpicius legatus; aberat etiam M. Antonius; exercebatur una lege iudicium Varia, ceteris propter bellum intermissis; cui frequens aderam, quamquam pro se ipsi dicebant oratores non illi quidem principes, L. Memmius et Q. Pompeius, sed oratores tamen, teste diserto utique [Jahn: MSS. uterque] Philippo, cuius in testimonio contentio et (...) vim accusatoris habebat et copiam. Reliqui qui turn principes numerabantur in magistratibus erant cotidieque fere a nobis in contionibus audiebantur …. (shrink)

It is the almost unanimous opinion of modern scholars' that this man is M. Licinius Crassus. Manutius's explanation, that ex Nanneianis is a reference to Crassus' profiteering in the proscriptions and in particular to the property of one Nanneius, to be identified with the Nannius named as a proscription victim in Comm. Pet. 9, is accepted without hesitation.