The current article is the first in a series of review articles addressing biosemiotic terminology. The biosemiotic glossary project is inclusive and designed to integrate views of a representative group of members within the biosemiotic community based on a standard survey and related publications. The methodology section describes the format of the survey conducted in November–December 2013 in preparation of the current review and targeted on the terms ‘agent’ and ‘agency’. Next, I summarize denotation, synonyms and antonyms, with special emphasis (...) on the denotation of these terms in current biosemiotic usage. The survey findings include ratings of nine citations defining or making use of the two terms. I provide a summary of respondents’ own definitions and suggested term usage. Further sections address etymology, connotations, and related terms in English and other languages. A section on the notions’ mainstream meaning vs. their meaning in biosemiotics is followed by attempt at synthesis and conclusions. Although there is currently no consensus in the biosemiotic community on what constitutes a semiotic agent, i.e., an agent in the context of semiosis, most respondents agree that core attributes of an agent include goal-directedness, self-governed activity, processing of semiosis and choice of action, with these features being vital for the functioning of the living system in question. I agree that these four features are constitutive of biosemiotic agents, and stipulate that biosemiotic agents fall within three major categories, namely 1) sub-organismic biosemiotic agents, 2) organismic biosemiotic agents and 3) super-organismic biosemiotic agents. (shrink)

According to this paper, respect for informed consent implies that subjects should often be told a good deal more than ethical guidelines explicitly or implicitly require. Unless subjects are informed of the researchers’ personal characteristics, views, and sponsors whenever they would be likely to consider them significant, their autonomy is being overridden. However, overriding subjects’ autonomy is sometimes required by the interests of researchers in not being discriminated against or suffering intrusions into their privacy. This paper resolves the conflict between (...) informed consent and the interests of researchers by recommending that (i) subjects generally should be told of the personal characteristics of researchers when relevant as part of the researchers’ job and (ii) that subjects should be told of researchers’ views when conceptually connected to the research and (iii) that subjects should almost always be told about sponsorship. While the paper explicitly limits the role of informed consent, these recommendations go significantly beyond most guidelines in their requirements about what information should be disclosed. (shrink)

The authors of the preceding articles1 raise legitimate questions about patient and staff rights and the unintended consequences of allowing ABC News to film inside teaching hospitals. We explain why we regard their fears as baseless and not supported by what we heard from individuals portrayed in the filming, our decade-long experience making medical documentaries, and the full un-aired context of the scenes shown in the broadcast. The authors don’t and can’t know what conversations we had, what documents we reviewed, (...) and what protections we put in place in each televised scene. Finally, we hope to correct several misleading examples cited by the authors as well as their offhand mischaracterization of our program as a “reality” show. (shrink)

We describe a broad class of problems, called “uncompromising problems,” which are characterized by the requirement that solutions must perform optimally on each of many test cases. Many of the problems that have long motivated genetic programming research, including the automation of many traditional programming tasks, are uncompromising. We describe and analyze the recently proposed “lexicase” parent selection algorithm and show that it can facilitate the solution of uncompromising problems by genetic programming. Unlike most traditional parent selection techniques, lexicase selection (...) does not base selection on a fitness value that is aggregated over all test cases; rather, it considers test cases one at a time in random order. We present results comparing lexicase selection to more traditional parent selection methods, including standard tournament selection and implicit fitness sharing, on four uncompromising problems: 1) finding terms in finite algebras; 2) designing digital multipliers; 3) counting words in files; and 4) performing symbolic regression of the factorial function. We provide evidence that lexicase selection maintains higher levels of population diversity than other selection methods, which may partially explain its utility as a parent selection algorithm in the context of uncompromising problems. (shrink)

La raccolta di contributi analizza alcuni dei temi più significativi dell’opera dello psicologo e filosofo Paolo Bozzi.

The author continues the preceding exchange of views on the nature of metaphor with the American philosopher Nelson Goodman that has been published in 'Poetics Today'. He offers his own theory of metaphor, which assumes a middle ground between Goodman's semantic theory and Davidson's pragmatic conception. The article also presents another argument in support of the thesis that there are only true metaphors, and that the logical space assumed by Goodman for the metaphorical falsehood is already reserved for the category (...) of statements that are nonsensical. (shrink)

Renal biopsy is a potentially hazardous procedure, generally performed for therapeutic reasons. An open renal biopsy was performed when there appeared to be no accepted clinical indication and its results published in a specialty journal, whose editors declined publication of subsequent correspondence, questioning the ethical propriety of such a procedure. The implications for clinical practice, authors, editors and readers are discussed.

Contingency-theorists have gestured to a series of phenomena such as random mutations or rare Armageddon-like events as that which accounts for evolutionary contingency. These phenomena constitute a class, which may be aptly called the ‘sources of contingency’. In this paper, I offer a probabilistic conception of what it is to be a source of contingency and then examine two major candidates: chance variation and genetic drift, both of which have historically been taken to be ‘chancy’ in a number of different (...) senses. However,contrathe gesturing of contingency-theorists, chance variation and genetic drift are not always strong sources of contingency, as they can be non-chancy in at least one sense that opposes evolutionary contingency. The probabilistic conception offered herein allows for sources of contingency to appropriately vary in strength. To this end, I import Shannon’sinformation entropyas a statistical measure for systematically assessing the strength of a source of contingency, which is part and parcel of identifying sources of contingency. In brief, the higher the entropy, the greater the strength. This is also empirically significant because molecular, mutational, and replicative studies often contain sufficient frequency or probability data to allow for entropies to be calculated. In this way, contingency-theorists can evaluate the strength of a source of contingency in real-world cases. Moreover, the probabilistic conception also makes conceptual room for the converse of sources of contingency: ‘sources of directionality’, which ought to be recognised, as they can interact with genuine sources of contingency in undermining evolutionary contingency. (shrink)

I would like to raise a pressing issue relating to the World Health Organization which should concern the medical profession throughout the UK. The WHO Charter advocates the provision of health to all—as a human right. It is therefore to be regretted that these Charter obligations have not been exercised with respect to Taiwan whose 23 million citizens still cannot benefit from its protection. This democratic country which is a beacon of human rights in Asia, is still excluded from the (...) WHO. It is expected that in 2005 the island will …. (shrink)