For the past two decades, agricultural workers in regions of Central America have reported an epidemic of chronic kidney disease of undetermined etiology (CKDu) that is not associated with established risk factors of chronic kidney disease. Several hypotheses have emerged, but the etiology of CKDu remains elusive and controversial. The aim of this literature review was to describe the potential risk factors of CKDu in Mesoamerica and implications for the U.S. agricultural worker population. PubMed and CINAHL databases were searched for (...) articles published between 2000 and 2018 that examined CKDu in Mesoamerica; 29 original studies were included in this review. CKDu is a multifactorial disease that is often asymptomatic with hallmark characteristics of elevated serum creatinine and blood urea nitrogen (BUN), low glomerular filtration rate, electrolyte abnormalities, and non-nephrotic proteinuria. Reducing the global prevalence of CKDu will require more robust studies on causal mechanisms and on interventions that can reduce morbidity and mortality in vulnerable populations. (shrink)

A vibrant portrait of four college friends-Iris Murdoch, Philippa Foot, Elizabeth Anscombe, and Mary Midgley-who formed a new philosophical tradition while Oxford's men were away at war.

When Sartre arrives late to meet Pierre at a local establishment, he discovers not merely that Pierre is absent, but Pierre’s absence, where this depends, or so Sartre notoriously supposes, on a frustrated expectation that Pierre would be seen at that place. Many philosophers have railed against this view, taking it to entail a treatment of the ontology of absence that Richard Gale describes as ‘attitudinal’ – one whereby absences are thought to ontologically depend on psychological attitudes. In this paper, (...) I aim to make Sartre’s intuition respectable. What Sartre perceives is an absential location, only the boundaries of which are circumscribed by what Sartre is doing at that place: meeting Pierre. I explain how this Sartrean view, though not specifically attributable to Sartre, nonetheless honours some of the phenomenological data described, if a little opaquely, in Being and Nothingness. (shrink)

Finance is an area that, in practice, is plagued by accusations of unethical activity; the study of finance had adopted a largely nonbehavioral approach to business ethics research. We address this gap in by assessing whether individual ethical orientations predict the acceptability of questionable decisions about financial issues. Results show that individual ethical orientations are associated with different levels of acceptability of questionable decisions about financial issues, though the pattern of these differences varies across individual ethical orientations assessed. These results (...) represent evidence that ethical individual differences are associated with the acceptability of questionable finance decisions and are discussed in terms of methodological limitations and future directions in finance ethics research. (shrink)

'Philosophy in a world of women. I reflected, talking with Mary, Pip and Elizabeth, how much I love them.' Two brilliant young scholars uncover the major philosophical contributions of four women whose ideas could have changed the course of twentieth-century thought. Written with energy, expertise and panache, The Quartet is a page-turning blend of research and recovery, storytelling, and a call to arms. Iris Murdoch, Philippa Foot, Mary Midgley and Elizabeth Anscombe were great friends and comrades in the intellectual trenches, (...) rethinking the possibilities of moral philosophy when the men 'left the room' and taking on the establishment, ultimately embodied by President Truman. Mac Cumhaill and Wiseman bring these women out of the shadows and into vivid colour. (shrink)

O artigo apresenta uma visão de conjunto do pensamento de Lima Vaz, a partir de seu método original, caracterizado por seu cunho rememorativo, dialético e sistemático. Ele é aplicado particularmente na Antropologia Filosófica e na Ética, sintetizando a categoria de história com a de transcendência, superando assim a crise do pensamento moderno à luz da práxis ética.

I present a novel anti-sceptical BIV argument by focusing on conditions on the production and use of the locative preposition ‘in’. I distinguish two uses of ‘in’—material and descriptive phenomenological—and I explain in what respect movement is central to the concept that our use of ‘in’ expresses. I go on to argue that a functionalist semantics of the intelligible use of ‘in’ demands a materialist philosophy of action in the spirit of G.E.M. Anscombe, but also why the structure of space (...) is not irrelevant either; appeal to the structure of space unsettles the causal-empirical assumptions that ground the picture of subjectivity and agency that the biv narrative assumes. Finally, I explain why a functionalist semantics demands a Naïve Realist metaphysics of perception, consistent with some of Putnam’s last writings on philosophy of perception. (shrink)

Se analizan fragmentos de Diodoro Sículo donde se manifiestan algunos de los mecanismos de dominación de los amos sobre los esclavos. Observamos larepresentación que se hace desde el discurso dominante del ejercicio del control social y el ocultamiento de las prácticas violentas propias de la relación esclavista. Se trata de fragmentos en donde aparecen referidas situaciones concretas, ocurridas tanto en el ámbito doméstico como en los espacios productivos. La teoría de la dominación social de O. Patterson y los conceptos del (...) análisis del discurso son fundamentos sobre los que se elabora nuestra perspectiva metodológica. (shrink)

This paper briefly examines the concept of the ancient mode of production as expressed in Karl Marx’s Formations. It looks at how twentieth-century Marxist historiography picks up this concept in its characterisation of the Greco-Roman city-state. It explores the feasibility of the use of the concept in relation to the advancement of knowledge of the city-state, especially through the development of archaeology. It examines how social classes are structured and relations of exploitation are presented. And it analyses the need for (...) politics in the organisation of this socio-economic form in terms of how it is joined up with the social relations of production. (shrink)

Om ett värdeobjektivistiskt inslag i Hägerströms moralfilosofiska teorier.--Till försvar för Zenon från Elea.--Den speciella relativitetsteoriens förhållande til de newtonianska föreställningarna om rum och tid.

El presente trabajo tiene como objetivo describir la funcionalidad discursivo-pragmática de sujetos adultos mayores sanos y con demencia leve, en sus aspectos de coherencia y coherencia pragmática, a través del análisis de producción lingüística oral, de ambos grupos, mediante la tarea denominada “monólogo audible” del protocolo MetAphAs. La muestra fue seleccionada de la base de datos NEUROLEN, en la cual se eligieron 9 sujetos sanos y 9 sujetos con demencia leve. Los datos fueron analizados desde una perspectiva de investigación cualitativa (...) descriptiva, con base en la funcionalidad discursiva-pragmática y la comparación con el marco teórico disponible. Los resultados arrojaron diferencias significativas en el desempeño de ambos grupos de senescentes. A pesar de presentar fallas en la producción del lenguaje a causa del envejecimiento fisiológico, los adultos mayores sanos son capaces de desarrollar comunicación funcional con su entorno, no ocurre lo mismo en el caso de los sujetos con demencia, debido a su deterioro cognitivo, el cual generaría dificultades en la producción discursiva. (shrink)

Las desigualdades sociales en Chile incluyen desigualdades territoriales que permanecen no observadas cuando se enfoca exclusivamente las regiones administrativas. Un conjunto entrelazado de tipos de territorios representativos del proceso de urbanización en un nivel subregional, es propuesto para el estudio de las desigualdades sociales desde una perspectiva territorial. Un territorio es delimitado por un mercado de trabajo común, lo que es medido por la conmutación o movilidad territorial.

The representation of events, in primates at any rate, is a separate process from their emotional evaluation. The same holds for cognitive evaluation. Here too representation and evaluation are separate operations. Acknowledging the symmetry leads to the notion of free representation.

O'Brien & Opie's connectionist interpretation of and depends heavily on the notions of and that underlie the classic account. When the assumptions, shared by both accounts, are removed, the connectionist versus classic contrast appears to be between behavioral and linguistic accounts.

Byrne & Russon's account of program imitation in primates involves propositional attitudes (expectations and goals), which limits its falsifiability. Yet their account of priming shows exactly how imitation without attitudes would look. The challenge is to upgrade the notion of priming to give an account of low-level program imitation without invoking propositional attitudes.

Notas al pie de Gaza es una novela gráfica del artista Joe Sacco en la que se retoma el conflicto palestino-israelí ya tratado en Palestina: En la Franja de Gaza. En esta obra se abocará a la investigación de dos matanzas cometidas el año 1956 en territorio palestino.. En este trabajo nos centraremos en el controvertido final de la novela, en la que Sacco, mediante una notable técnica gráfica, obliga al lector a convertirse en una de las víctimas de la (...) matanza de Rafah. ¿Es esta técnica válida o éticamente cuestionable? Para contestar a esta pregunta buscaremos orientación mediante conceptos descriptivos de Dominick LaCapra y de Judith Butler. Este ejercicio teórico previo nos permitirá retomar una evaluación crítica más serena y exacta. (shrink)

It is often said nowadays that to understand pleasure we must understand it as affording us a reason for or an explanation of action. It is only from the standpoint of the agent that we can avoid being misled. Both Professor Nowell-Smith and Mr. Manser have argued along these lines; and Dr. Kenny has written that “pleasure is always a reason for action” and has elucidated what he means by a footnote: “I do not mean that a thing’s being pleasant (...) is always a sufficient reason for doing it; there may be strong reasons for abstaining. I mean merely that it is always silly to ask a man why he wants pleasure.” When I first saw this point made, I had the perhaps not uncommon philosophical experience of immediately finding it both lucid and convincing, but then, afterwards gradually becoming less and less clear about the source of my conviction. The reasons for my obfuscation are as follows. In one crucial sense anything can afford an agent with a reason for action. It depends upon what the agent wants and upon the projects in which he is engaged. Moreover, without having any strong reasons for abstaining from what will give me pleasure, I may not be at all moved by the prospect of pleasure. As I write this paper I can list a dozen activities or experiences which would afford me pleasure. I have no strong reason for abstaining; I do not particularly enjoy writing papers; I am not writing with a great sense of urgency; I have the time and the money to indulge myself. Yet I do not rush to open a Guinness or Mr. Alfred Grossman’s new novel. So that far from it being silly to ask me why I do not apparently want pleasure at the moment, it is a question that I find forced upon me. But if this question makes sense, there is at least a problem as to why “it is always silly to ask a man if he wants pleasure.” For one might expect the two questions to stand or fall together. This is the problem to which I address myself in this paper. But in order to do so I must first take up certain points from recent discussions which are in danger of preventing a solution. (shrink)

Resumen: El trabajo se centra en la lectura de Fantomas contra los vampiros multinacionales, obra de Julio Cortázar de gran complejidad, un híbrido que hasta el momento ha sido poco difundido. La obra presenta la problemática entre compromiso ético y compromiso estético, ya que se centra en la asistencia y participación de Julio Cortázar en las sesiones del Tribunal Russell y las violaciones a los derechos humanos en países latinoamericanos. La propuesta de lectura es la de considerar la relación de (...) lo ético y lo estético desde el concepto derridiano de suplemento. Es decir, lo ético no sería un elemento marginal, tampoco habría una jerarquización entre ambos. El suplemento implica un nuevo modo de pensar toda relación binominal.: This work focuses on the interpretation of Fantomas contra los vampiros multinacionales,a narrative of great complexity by Julio Cortázar, a hybrid that is not so well-known. The novel presents the problematic between ethical commitment and aesthetical commitment, since it is focused on the assistance and participation of Cortázar on the Russel Tribunal sessions and human rights violations in Latin American countries. The proposal for interpretation is to consider the relationship between the ethical and the aesthetical in light of the derridian concept of supplement. In other words, the ethical is not a marginal element, and there are no hierarchical differences between both. The supplement implies a new way of thinking about all binomial relationships. (shrink)

This selection is an argument for the pharmacology of cannabinoids. It also provides a phenotypical account of the botany of cannabis.

I offer a reading of Murdoch's conception of concrete universality as it appears in 'The Idea of Perfection', the first essay in the Sovereignty of Good. I show that it has British Idealist overtones that are inflected by Wittgenstein, a thought I try to illuminate by drawing an analogy with Wittgenstein's discussion of the metre stick in Paris in Philosophical Investigations §50. In the last part of the paper, I appeal to the work of Murdoch's erstwhile tutor Donald MacKinnon to (...) respond to an objection to my strategy, which I draw from Murdoch's later work, Metaphysics as a Guide to Morals. (shrink)

Social problems such as racism, sexism, and inequality are often cited as structural rather than individual in nature. What does it mean to invoke a social structural explanation, and how do such explanations relate to individualistic ones? This article explores recent philosophical debates concerning the nature and usages of social structural explanation. I distinguish between two central kinds of social structural explanation: those that are autonomous from psychology, and those that are not. This distinction will help clarify the explanatory power (...) that each type of SSE has, points of convergence with methodological traditions such as critical theory and rational choice theory, and the difficulties that each type of SSE faces. (shrink)