BackgroundThe Public Health Service Increased Risk designation identified organ donors at increased risk of transmitting hepatitis B, hepatitis C, and human immunodeficiency virus. Despite clear data demonstrating a low absolute risk of disease transmission from these donors, patients are hesitant to consent to receiving organs from these donors. We hypothesize that patients who consent to receiving offers from these donors have decreased time to transplant and decreased waitlist mortality.MethodsWe performed a single-center retrospective review of all-comers waitlisted for liver transplant from (...) 2013 to 2019. The three competing risk events (transplant, death, and removal from transplant list) were analyzed. 1603 patients were included, of which 1244 (77.6%) consented to offers from increased risk donors.ResultsCompared to those who did not consent, those who did had 2.3 times the rate of transplant (SHR 2.29, 95% CI 1.88–2.79, p < 0.0001), with a median time to transplant of 11 months versus 14 months (p < 0.0001), as well as a 44% decrease in the rate of death on the waitlist (SHR 0.56, 95% CI 0.42–0.74, p < 0.0001). All findings remained significant after controlling for the recipient age, race, gender, blood type, and MELD. Of those who did not consent, 63/359 (17.5%) received a transplant, all of which were from standard criteria donors, and of those who did consent, 615/1244 (49.4%) received a transplant, of which 183/615 (29.8%) were from increased risk donors.ConclusionsThe findings of decreased rates of transplantation and increased risk of death on the waiting list by patients who were unwilling to accept risks of viral transmission of 1/300–1/1000 in the worst case scenarios suggests that this consent process may be harmful especially when involving “trigger” words such as HIV. The rigor of the consent process for the use of these organs was recently changed but a broader discussion about informed consent in similar situations is important. (shrink)

Although there is no more iconic, stalwart, and eloquent defender of liberty and representative democracy than J.S. Mill, he sometimes endorses non-democratic forms of governance. This article explains the reasons behind this seeming aberration and shows that Mill actually has complex and nuanced views of the transition from non-democratic to democratic government, including the comprehensive and parallel material, cultural, institutional, and character reforms that must occur, and the mechanism by which they will be enacted. Namely, an enlightened despot must cultivate (...) democratic virtues such as obedience, industriousness, spirit of nationality, and resistance to tyranny in the population and simultaneously prepare the way for his own demise and secure his own legitimacy by transitioning to the rule of law. This challenges recent scholarship that paints Mill’s non-democratic views as crudely and uncritically imperialist, because it fails to recognize and engage seriously with his sophisticated (if ultimately problematic) theory of individual and institutional development under enlightened colonialism. (shrink)

Es gibt offensichtlich nicht nur Moden der Kleidung, der Frisur oder des Wohnens, sondern auch Moden in den Wissenschaften, in Kunst, Philosophie und vielleicht sogar in der Religion. Das heisst aber gerade in Bereichen, die doch eigentlich 'feste Prinzipien' gegen den Wechsel des Zeitgeistes und der Moden verteidigen. Aber was bedeutet dann in diesen Zusammenhängen "Mode"? Und wie lassen sich solche geistigen Moden erklären? Gehören "Mode" und "Moderne" zusammen? Der vorliegende Band versucht eine systematische Antwort auf diese Fragen, indem er (...) zunächst das Phänomen des Modischen auf seinen offenkundigen Feldern untersucht: den Kleidungsmoden, Wohnmoden, Körpermoden und den Moden in Freizeitgestaltung und Tourismus sowie im Sport. Von hier aus wird nach den spezifisch intellektuellen Moden in den Natur- und Geisteswissenschaften, in der Kunst, in der Philosophie und in der Religion gefragt. Mit Beiträgen von: Georg Bertram, Hubertus Busche, Yvonne Förster, Robert Gugutzer, Rainer Hartmann, Frank Hillebrandt, Paul Hoyningen-Huene, Irene Nierhaus, Daria Pezzoli-Olgiati, Verena Potthoff, Tim Rojek. (shrink)

In this paper, I offer an intellectual-historical reading of Foucault’s unpublished master’s thesis. In contrast with other recent scholarship on the pre-1961 period of Foucault’s career, the purpose of this paper is to grapple with the philosophical content of this thesis on its own terms, distinguishing it as far as possible from his mature work. This allows forgotten concepts to re-emerge in the course of reading the text and for a novel engagement with such neglected facets of Foucault’s oeuvre. Indeed, (...) the key concept which I argue emerges from Foucault’s early thesis is that of language as the être-la of thought. By closely following Foucault’s Husserlian reading of Hegel, and his response to Eugen Fink’s paradoxes of phenomenology, it is possible to see how Foucault briefly lands upon a novel kind of scepticism about the reality of history and minds. In the same way, I will also show why Foucault was unable to fully develop or commit to these sceptical positions during this part of his career. The article concludes by briefly suggesting contrasts between my reading of this early text and the way Foucault’s oeuvre is more generally understood. (shrink)

Exponents and critics of semantic presupposition have almost invariably based their discussion on the ('Standard') definition of presupposition implied by Frege and Strawson. In this study Noel Burton-Roberts argues convincingly against this definition, that leads it to a three-valued semantics. He presents a very simple semantic definition which is weaker, more general and leads to a semantics more easily interpreted as two-valued with gaps. The author shows that a wide range of intuitive facts that eluded the Standard definition follow (...) directly from this ('Revised') definition itself: facts about the presuppositions of compound sentences and modal sentences, about presuppositional conflict and about differences in the logical status of simple sentences suffering from presupposition failure. The book includes a detailed argument that an ambiguity of natural language negation, generally assumed to be necessary to the defence of semantic presupposition, is neither possible nor necessary in a presuppositional semantics. Noel Burton-Roberts has made an authoritative contribution to a debate which has involved philosophers and linguists for many years. His command of the issues, his clarity of exposition and his theoretical insight may well serve to change the boundaries of that debate. (shrink)

This thesis is an investigation of the question of the probative force of the syllogism. It examines on what the probative force of propositions constituting an argument depends and some of the cases in which the conclusion of a syllogism is and is not proven by the premises. The investigation begins by looking at certain preliminary notions associated with arguments in general and categorical syllogisms in particular. In each categorical syllogism are found two claims. One is the claim to truth (...) made by each proposition, and another is the claim to validity made by the syllogism. When each of these claims are fulfilled the syllogism is then sound. The question is whether or not every sound syllogism also represents a proof of the conclusion. John Stuart Mill asserted that no deductive argument including the syllogism can be a proof of the truth of the conclusion on the grounds that the premises presuppose the conclusion. In fact each syllogism is an example of the fallacy of petitio principii which it must by its very nature commit. Alexander Pfänder instead claimed that only in certain cases is the conclusion not proven by the premises, while in other cases the truth of the conclusion is actually proven by the truth of the premises. An independent investigation of the question of the probative force of the syllogism is made. Because of a crucial difference between propositions affirming contingent states of fact and essentially necessary propositions affirming necessary states of fact, it is shown that no syllogism containing contingent propositions can be a proof, while a proof is present in the case of a syllogism containing essentially necessary propositions. When the propositions of an argument are contingent their truth follows from the fact each particular existing instance they refer to actually has what is affirmed by the proposition. Therefore, if the syllogism is valid, the conclusion will refer to at least some of the same particular existing instances on which the truth of each of the premises depends. The premises can be true only if the conclusion is true, and any uncertainty about the truth of the conclusion extends also to the premises. The premises cannot prove the truth of the conclusion since their truth presupposes the truth of the conclusion. Propositions which are essentially necessary are true regardless of whether or not any particular instance exists or will ever exist. Because the state of fact is essentially necessary, the predicate is intelligibly grounded necessarily in the subject. If these kinds of propositions are found in a syllogism, their truth will not depend on the truth of a conclusion. Essentially necessary propositions have probative force, and their presence in a valid argument results in an actual proof of the conclusion. (shrink)

1 INTRODUCTION Above the other titles he might justly have claimed, Charles S. Peirce prized the title 'logician'. He expressed in several places his ...

Since the publication of Edmund Gettier's challenge to the traditional epistemological doctrine of knowledge as justified true belief, Roberts and Wood claim that epistemologists lapsed into despondency and are currently open to novel approaches. One such approach is virtue epistemology, which can be divided into virtues as proper functions or epistemic character traits. The authors propose a notion of regulative epistemology, as opposed to a strict analytic epistemology, based on intellectual virtues that function not as rules or even as (...) skills but as habits of the heart. To that end, they divide the task of clarifying and expounding their notion in the book's two parts.In the first part, Roberts and Wood examine various components that constitute their notion of regulative epistemology. The first are the epistemic goods or goals that drive the epistemic process. What is needed, claim Roberts and Wood, is an enriched notion of these goods rather than the restricted notion of justified true belief. Epistemic agents are more than calculating devices in that …. (shrink)

This essay analyzes the known evidence for Byzantine engagement with what are conventionally termed “alchemical” texts, theories, and practices of the Islamic world. Much of the evidence is difficult to date. Nevertheless, the aggregated direct, indirect, and circumstantial evidence suggests at least some engagement by Greek-speaking scholars throughout the Middle Ages. This engagement took various forms, from the use of Arabic, Persian, and Turkish terminology to the adaptation of whole Arabic treatises in Greek. Sometimes the Byzantine texts emphasize their Islamicate (...) sources, and sometimes they do not mention these sources at all. The resulting picture is still fragmentary, but it indicates that medieval Greek-speaking scholars were active in the circulation of chemical knowledge and techniques in the Mediterranean and Middle East. Byzantium, therefore, should no longer be left out of research into long-term patterns in the history of science. (shrink)

A critical analysis of theories of commercial impossibility and frustration of purpose is best undertaken in conjunction with a theoretical analysis of contract in general. Contracts function as a means of transferring social benefit, which can be subcategorised into subjective and objective benefit. Contracts also regulate the transfer or risk, which is inherent in property and hence any contractual relationship. In the light of the transfer of subjective and objective benefit and risk, contracts can be shown to be by definition (...) ex ante Pareto superior for both parties. Frustration of purpose or commercial impossibility is pleaded where the ex post overall benefit differs greatly from the ex ante expected value. This difference results from the manifestation of a risk which one party bears under the terms of the original contractual risk/benefit equilibrium. Considering the various subjective and objective risks and benefits involved in the contract, it is possible to classify frustrating eventualities under eight heads. In at least six cases the importance of the principle of security of exchange clearly precludes the operation of frustration. One of the remaining cases corresponds with the controversial Krell v Henry; there appears to be a temptation to regard frustration as the most socially utilitarian solution. Given however the dynamics of contractual risk and benefit, allowing frustration there would be unworkable because it would entail placing a subjective risk burden on the party which is in a worse position to evaluate it. There should be no place in the law for a doctrine of frustration of contract on the grounds of commercial impossibility orchanged circumstances. (shrink)

A framework for pragmatic analysis is proposed which treats discourse as a game, with context as a scoreboard organized around the questions under discussion by the interlocutors. The framework is intended to be coordinated with a dynamic compositional semantics. Accordingly, the context of utterance is modeled as a tuple of different types of information, and the questions therein — modeled, as is usual in formal semantics, as alternative sets of propositions — constrain the felicitous flow of discourse. A requirement of (...) Relevance is satisfied by an utterance (whether an assertion, a question or a suggestion) iff it addresses the question under discussion. Finally, it is argued that the prosodic focus of an utterance canonically serves to reflect the question under discussion (at least in English), placing additional constraints on felicity in context. (shrink)

In recent years, policymakers, academics, and practitioners have increasingly called for the development of global governance mechanisms for artificial intelligence (AI). This paper considers the prospects for these calls in light of two other geopolitical trends: digital sovereignty and digital expansionism. While calls for global AI governance promote the surrender of some state sovereignty over AI, digital sovereignty and expansionism seek to secure greater state control over digital technologies. To demystify the tensions between these trends and their potential consequences, we (...) undertake a case analysis of digital sovereignty and digital expansionism in China, the European Union, and the United States. We argue that the extraterritoriality embedded in these three actors’ policies and escalatory competitive narratives, particularly those from the US, will likely undermine substantive global AI governance cooperation. However, nascent areas of alignment or compromise, notably in data governance and technical standards, could prove fruitful starting points for building trust in multilateral fora, such as the G20 or United Nations. (shrink)

In recent years, the public sphere, which represents a realm in civil society where people can debate and discuss a range of issues and common concerns important to them, has become a key area for research in the humanities and social sciences. Arguably, however, Marxist theory has yet to advance a theoretical account of the most abstract and simple ideological properties of the capitalist public sphere as these appear under universal commodity relationships. The paper therefore tentatively seeks to develop such (...) an account. Specifically, the paper theoretically derives a peculiar public sphere under capitalism, which is mediated between at least two commodity owners who also possess distinctive personalities driven by desires to own commodities. The paper then explains in more detail how the social form of this public sphere develops through other elements of commodity relations and their contradictions. (shrink)

T. A. Roberts; III—Morality and Divine Commands, Proceedings of the Aristotelian Society, Volume 68, Issue 1, 1 June 1968, Pages 49–62, https://doi.org/10.1093/.

This paper describes the research carried out into small and medium enterprises (SMEs) and corporate responsibility (CR) in the Northwest of England during Phase I of Responsibility Northwest, a partnership programme designed to significantly increase the CR of the region. By engaging with significant numbers of SMEs and SME support providers across the region, key insights were gained in three key areas: • The current attitudes to, understanding of, and management of CR issues in the SME sector.• The barriers to (...) greater implementation of CR management.• The opportunities for overcoming the barriers and improving regional CR. The research revealed a large diversity both in terms of understanding of the issues and their management. Seven key barriers to improve CR performance were identified which centred round the inappropriateness and inaccessibility of current CR approaches and support services on CR, certain characteristics of SMEs which tend to reduce their interest and opportunities for engaging in CR activities and supply-chain barriers. Fortunately there was significant agreement on the mechanisms which should be used to overcome these barriers, in particular the importance of delivering CR support through existing business networks that are valued and trusted by SMEs. These results have been used to create the partnership programme, Responsibility Northwest Phase II that runs until 2008 and aims to significantly increase the overall CR of Northwest England. (shrink)

This paper describes some of the experiences of working with teenage girls' friendship groups at 'Hilltop', a large urban comprehensive school in the north of England. Working between and within mu...

The pessimistic arguments May challenges depend on an anti-Kantian philosophical assumption. That assumption is that what I call philosophical optimists about moral reason are also committed to empirical optimism, or what May calls “optimistic rationalism.” I place May's book in the literature by explaining how that assumption is resisted by Christine Korsgaard, one of May's examples of a contemporary Kantian.

The COVID-19 pandemic brought unprecedented changes to daily life and in the first wave in the UK, it led to a societal shutdown including playing sport and concern was placed for the mental health of athletes. Identifying mood states experienced in lockdown and self-regulating strategies is useful for the development of interventions to help mood management. Whilst this can be done on a general level, examination of sport-specific effects and the experience of athletes and coaches can help develop interventions grounded (...) in real world experiences. The present study investigated perceived differences in mood states of boxers before and during COVID-19 isolation in the first lockdown among boxers. Boxing is an individual and high-contact sport where training tends to form a key aspect of their identity. Boxers develop close relationships with their coach and boxing. Hence boxers were vulnerable to experiencing negative mood, and support via the coach was potentially unavailable. Participants were 58 experienced participants. Boxers completed the Brunel Mood Scale to assess mood before COVID-19 using a retrospective approach and during COVID-19 using a “right now” time frame. Boxers responded to open-ended questions to capture mood regulation strategies used. Coaches responded to open ended questions to capture how they helped regulate boxer’s mood. MANOVA results indicated a large significant increase in the intensity of unpleasant moods and reduction in vigor during COVID-19. Using Lane and Terry conceptual framework, results showed participants reporting depressed mood also reported an extremely negative mood profile as hypothesized. Qualitative data indicated that effective mood-regulation strategies used included maintaining close coach-athlete contact and helping create a sense of making progress in training. When seen collectively, findings illustrate that mood state responses to COVID-19 were severe. It is suggested that that active self-regulation and self-care should be a feature of training programmes to aid coaches and boxers in regulating mood when faced with severe situational changes. (shrink)

A call to Christian discipleship that draws on the works of Søren Kierkegaard to illustrate how prevailing notions of Christianity are often at odds with genuine Christian character.

Random-excitation granule cells are likely to overwhelm spatiotemporal sequences described as in Braitenberg et al.'s target article. A mechanism is proposed involving the Golgi cells to reinforce tidal waves against noise. The recurrent inhibition by the Golgi calls can recruit random excitations of granule cells in phase with sequences of mossy fiber input.

The premise of this paper is that an adequate model of consciousness will be able to account for the fundamental duality in experience typified by thought and feeling, objectivity and subjectivity, science and art, and that it will do so without any of these terms assimilating its counterpart. The paper argues that such an account is possible using existing models of the cell assembly, but only if consciousness is conceived in structural rather than information processing terms. To this end, the (...) paper contests the viability of information processing models that identify consciousness with a substrate-independent flow of information, and instead identifies consciousness with the physical structure of the cell assembly itself. This allows a fuller and more parsimonious account of consciousness than existing information processing models, as well as the integration of a range of key related matters from the fields of neuroanatomy, psychology, philosophy, and the physical sciences. (shrink)

In the 1980s, leading philosophers at Oxford, Chicago and UCLA undertook a controversial reassessment of Marxism using the techniques of analytical philosophy. The aim of these so-called "Non-Bullshit" Marxists was no less than the complete reconstruction of Marxist theory, recasting it on a logical and rigorous basis, free from all metaphysical jargon and sentimentality. Marcus Roberts's study serves as a lucid survey of the Analytical Marxists' contributions to the understanding of historical materialism, exploitation, class structure, method, politics and ethics—a (...) panoramic tour de force which he brings up to date with considerations on John Roemer's recent work on models of socialism. Roberts charts the sinuous progress of the growth, development and ultimate dilution or disintegration of the bold theses originally put forward by such figures as Gerry Cohen, Jon Elster and John Roemer. For Roberts, the Analytical Marxist project, for all its elegance and richness, failed on its own terms, and in terms of Marxism more generally. However, as this book so persuasively demonstrates, along its winding route, the project raised questions of fundamental importance for social and political theory—questions that anyone interested in emancipation cannot avoid taking seriously. (shrink)

Are historians storytellers? Is it possible to tell true stories about the past? These are just a couple of the questions raised in this comprehensive collection of texts about philosophy, theory, and methodology of writing history. Drawing together seminal texts from philosophers and historians, this volume presents the great debate over the narrative character of history from the 1960s onwards. The History and Narrative Reader combines theory with practice to offer a unique overview of this debate and illuminates the practical (...) implications of these philosophical debates for the writing of history. The editor's introduction offers a succinct survey of the subject to support the readings, which explore the role of narrative in everything from historical understanding and human action to linguistics and the practice of history. Including the work of F. R. Ankersmit, David Carr, Hayden White, W. H. Dray, and Frederick Olafson; a detailed bibliography; and a glossary of key concepts, this collection will prove an invaluable resource for students of historical theory and methodology. (shrink)