Results for 'bet-hedging'

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  1. Bet hedging or not? A guide to proper classification of microbial survival strategies.Imke G. de Jong, Patsy Haccou & Oscar P. Kuipers - 2011 - Bioessays 33 (3):215-223.
    Bacteria have developed an impressive ability to survive and propagate in highly diverse and changing environments by evolving phenotypic heterogeneity. Phenotypic heterogeneity ensures that a subpopulation is well prepared for environmental changes. The expression bet hedging is commonly (but often incorrectly) used by molecular biologists to describe any observed phenotypic heterogeneity. In evolutionary biology, however, bet hedging denotes a risk‐spreading strategy displayed by isogenic populations that evolved in unpredictably changing environments. Opposed to other survival strategies, bet hedging (...)
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  2.  21
    From developmental to atavistic bet‐hedging: How cancer cells pervert the exploitation of random single‐cell phenotypic fluctuations.Jean-Pascal Capp & Frédéric Thomas - 2022 - Bioessays 44 (9):2200048.
    Stochastic gene expression plays a leading developmental role through its contribution to cell differentiation. It is also proposed to promote phenotypic diversification in malignant cells. However, it remains unclear if these two forms of cellular bet‐hedging are identical or rather display distinct features. Here we argue that bet‐hedging phenomena in cancer cells are more similar to those occurring in unicellular organisms than to those of normal metazoan cells. We further propose that the atavistic bet‐hedging strategies in cancer (...)
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  3.  33
    Mutational heterogeneity: A key ingredient of bet‐hedging and evolutionary divergence?Thomas Ferenci & Ram Maharjan - 2015 - Bioessays 37 (2):123-130.
    Here, we propose that the heterogeneity of mutational types in populations underpins alternative pathways of evolutionary adaptation. Point mutations, deletions, insertions, transpositions and duplications cause different biological effects and provide distinct adaptive possibilities. Experimental evidence for this notion comes from the mutational origins of adaptive radiations in large, clonal bacterial populations. Independent sympatric lineages with different phenotypes arise from distinct genetic events including gene duplication, different insertion sequence movements and several independent point mutations. The breadth of the mutational spectrum in (...)
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  4.  32
    At Law: Hedging Their Bets.Alexander Morgan Capron - 1993 - Hastings Center Report 23 (3):30.
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  5.  40
    Assortative Pairing and Life History Strategy.Aurelio José Figueredo & Pedro S. A. Wolf - 2009 - Human Nature 20 (3):317-330.
    A secondary analysis was performed on preliminary data from an ongoing cross-cultural study on assortative pairing. Independently sampled pairs of opposite-sex romantic partners and of same-sex friends rated themselves and each other on Life History (LH) strategy and mate value. Data were collected in local bars, clubs, coffeehouses, and other public places from three different cultures: Tucson, Arizona; Hermosillo, Sonora; and San José, Costa Rica. The present analysis found that slow LH individuals assortatively pair with both sexual and social partners (...)
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  6.  18
    Variation is function: Are single cell differences functionally important?Hannah Dueck, James Eberwine & Junhyong Kim - 2016 - Bioessays 38 (2):172-180.
    There is a growing appreciation of the extent of transcriptome variation across individual cells of the same cell type. While expression variation may be a byproduct of, for example, dynamic or homeostatic processes, here we consider whether single‐cell molecular variation per se might be crucial for population‐level function. Under this hypothesis, molecular variation indicates a diversity of hidden functional capacities within an ensemble of “identical” cells, and this functional diversity facilitates collective behavior that would be inaccessible to a homogenous population. (...)
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  7.  7
    Can a Theory of Content Rely on Selected Effect Functions? Response to Christie, Brusse, et al.Nicholas Shea - 2022 - Australasian Philosophical Review 6 (4):400-411.
    In the target article, Christie, Brusse, et al. argue that selected effect functions do not, in general, explain why a trait exists in a population and, therefore, theories of representational content should not rely on selected effect functions. This response focuses on the claim about functions-for-representation. The role of evolutionary functions in a theory of content is to pick out outcomes that have been systematically stabilized by natural selection. Correctness conditions are conditions involved in explaining how that happened. Selected effect (...)
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  8.  5
    Changing the Subject? Christie, Brusse, et al. on the Selected Effects Account of Biological Function.Justine Kingsbury - 2022 - Australasian Philosophical Review 6 (4):367-373.
    In ‘Are biological traits explained by their “selected effect” functions?’, Christie, Brusse, Bourrat, Takacs, and Griffiths argue that selected effect functions only explain the presence of a trait (or the frequency of a trait in a population) in cases in which the selective environment has been uniform, illustrating their point with cases of coevolution, frequency-dependent selection, and bet-hedging. This commentary suggests that selected effect functions are explanatory even in those cases, and that Christie, Brusse, et al. are mistaken about (...)
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  9.  39
    Post‐Transcriptional Noise Control.Maike M. K. Hansen & Leor S. Weinberger - 2019 - Bioessays 41 (7):1900044.
    Recent evidence indicates that transcriptional bursts are intrinsically amplified by messenger RNA cytoplasmic processing to generate large stochastic fluctuations in protein levels. These fluctuations can be exploited by cells to enable probabilistic bet‐hedging decisions. But large fluctuations in gene expression can also destabilize cell‐fate commitment. Thus, it is unclear if cells temporally switch from high to low noise, and what mechanisms enable this switch. Here, the discovery of a post‐transcriptional mechanism that attenuates noise in HIV is reviewed. Early in (...)
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  10.  3
    Niche-construction: Environmental Heterogeneity as a Selected Effect.Clint Hurshman - 2022 - Australasian Philosophical Review 6 (4):424-428.
    Joshua Christie, Carl Brusse, Pierrick Bourrat, Peter Takacs, and Paul Griffiths argue that selected-effects (SE) functions generally fail to causally explain traits because they omit some explanatorily essential information. Heterogeneous environments, bet-hedging strategies, and frequency-dependence all produce selection dynamics that are explanatorily important but that are left out when we focus exclusively on the conditions under which a given trait was adaptive. Thus, they argue, the SE theory gives inadequate explanations since it only picks out a limited set of (...)
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  11.  68
    Reasoning with uncertain categories.Gregory L. Murphy, Stephanie Y. Chen & Brian H. Ross - 2012 - Thinking and Reasoning 18 (1):81 - 117.
    Five experiments investigated how people use categories to make inductions about objects whose categorisation is uncertain. Normatively, they should consider all the categories the object might be in and use a weighted combination of information from all the categories: bet-hedging. The experiments presented people with simple, artificial categories and asked them to make an induction about a new object that was most likely in one category but possibly in another. The results showed that the majority of people focused on (...)
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  12.  43
    Style Management: Images of Global Counter-Terrorism at the United Nations.Isobel Roele - 2022 - Law and Critique 33 (3):273-297.
    Models of global governance abound: expert governance, networked governance, algorithmic governance, and old-fashioned juridico-political governance vie for explanatory power. This article takes up style as a way of analysing configurations of governance that do not readily fit a particular model of governance. Style is particularly revealing when it comes to deliberately unspecified or over-specified, genre-busting, and bet-hedging ways of imagining governance. The UN’s use of the phrase ‘convening power’ is a case in point. This article looks at how the (...)
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  13. Fundamental Dimensions of Environmental Risk.Bruce J. Ellis, Aurelio José Figueredo, Barbara H. Brumbach & Gabriel L. Schlomer - 2009 - Human Nature 20 (2):204-268.
    The current paper synthesizes theory and data from the field of life history (LH) evolution to advance a new developmental theory of variation in human LH strategies. The theory posits that clusters of correlated LH traits (e.g., timing of puberty, age at sexual debut and first birth, parental investment strategies) lie on a slow-to-fast continuum; that harshness (externally caused levels of morbidity-mortality) and unpredictability (spatial-temporal variation in harshness) are the most fundamental environmental influences on the evolution and development of LH (...)
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  14.  35
    Global Derivatives Market.Aleksandra Stankovska - 2016 - Seeu Review 12 (1):81-93.
    Globalization of financial markets led to the enormous growth of volume and diversification of financial transactions. Financial derivatives were the basic elements of this growth. Derivatives play a useful and important role in hedging and risk management, but they also pose several dangers to the stability of financial markets and thereby the overall economy. Derivatives are used to hedge and speculate the risk associated with commerce and finance. When used to hedge risks, derivative instruments transfer the risks from the (...)
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  15.  54
    A fairy tale from before fairy tales: Egbert of Liege's “De puella a lupellis seruata” and the medieval background of “Little Red Riding Hood”.Jan M. Ziolkowski - 1992 - Speculum 67 (3):549-575.
    One vivid description of folktale research, still applicable although more than a half century old, reads, “Folktale study is like a desert journey, where the only landmarks are the bleached bones of earlier theories.” Because theories have proven to be so ephemeral in comparison with the tales themselves , it might seem prudent to place more stock in the tales and less in the theories or at least to take an eclectic approach toward theorizing so as to hedge bets; but (...)
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  16. The Evidentialist's Wager.William MacAskill, Aron Vallinder, Caspar Oesterheld, Carl Shulman & Johannes Treutlein - 2021 - Journal of Philosophy 118 (6):320-342.
    Suppose that an altruistic agent who is uncertain between evidential and causal decision theory finds herself in a situation where these theories give conflicting verdicts. We argue that even if she has significantly higher credence in CDT, she should nevertheless act in accordance with EDT. First, we claim that the appropriate response to normative uncertainty is to hedge one's bets. That is, if the stakes are much higher on one theory than another, and the credences you assign to each of (...)
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  17. Disagreement or denialism? “Invasive species denialism” and ethical disagreement in science.David M. Frank - 2019 - Synthese 198 (Suppl 25):6085-6113.
    Recently, invasion biologists have argued that some of the skepticism expressed in the scientific and lay literatures about the risks of invasive species and other aspects of the consensus within invasion biology is a kind of science denialism. This paper presents an argument that, while some claims made by skeptics of invasion biology share important features with paradigm cases of science denialism, others express legitimate ethical concerns that, even if one disagrees, should not be dismissed as denialist. Further, this case (...)
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  18.  78
    In Defense of Fakes and Artistic Treason: Why Visually-Indistinguishable Duplicates of Paintings Are Just as Good as the Originals. [REVIEW]Peter Martin Jaworski - 2013 - Journal of Value Inquiry 47 (4):391-405.
    I argue that all that is relevant to appreciating art as art is the "abstract entity that is the work of art." The object of aesthetic contemplation, the bearer of aesthetic value, just is this abstract entity picked out by the sortal concept 'work of art,' which requires some vehicle but does not require the particular vehicle that is the original painting. Since this is so, the work of art is present in a visually-indistinguishable duplicate to the same extent and (...)
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  19.  85
    Derivatives and Capitalist Markets: The Speculative Heart of Capital.Tony Norfield - 2012 - Historical Materialism 20 (1):103-132.
    Financial derivatives have been singled out as the major villain in the latest crisis, particularly through speculative trading by banks. Yet little attention has been paid to the fundamental rôle that derivatives play in modern capitalism. Even less has there been a focus on how the boom in derivatives-trading was prompted by the crisis of profitability and capital-accumulation. This article shows that while derivatives were one means by which speculation took off, the momentum behind this was driven by low profitability. (...)
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  20. Petrick, JA and Qulnn, JF, Management Ethics: Integrity at Work.Pamela M. Hedges - 1999 - Teaching Business Ethics 3 (4):401-402.
     
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  21.  25
    From the margins of the genome: mobile elements shape primate evolution.Dale J. Hedges & Mark A. Batzer - 2005 - Bioessays 27 (8):785-794.
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  22.  32
    Constraining fossil calibrations for molecular clocks.S. Blair Hedges, Sudhir Kumar & Marcel van Tuinen - 2006 - Bioessays 28 (7):770-771.
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  23. New Developments in Archaeological Science.R. E. M. Hedges & B. C. Sykes - 1992
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  24.  25
    Post-Face Translation/Transformation.Inez Hedges - 1977 - Substance 6 (16):172.
  25.  26
    Statistical summaries in research integration.Larry V. Hedges - 1983 - Behavioral and Brain Sciences 6 (2):295-296.
  26. Tranquilina Evangelista: Light of My Life.Bet E. Montecillo - 2010 - Budhi: A Journal of Ideas and Culture 14 (2 & 3):307-310.
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  27.  24
    Is John Milbank's radical orthodoxy a form of liberal theology? A rhetorical counter.Paul Hedges - 2010 - Heythrop Journal 51 (5):795-818.
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  28.  18
    Présentation.Estelle Poirot-Betting - 2020 - Revue des Sciences Philosophiques Et Théologiques 103 (1):3-6.
    L’article a pour objectif de rendre compte du réalisme critique introduit par le théologien Ian Barbour afin d’établir un « pont » entre science et théologie. Nous verrons pourquoi et comment Ian Barbour utilise cette philosophie qui relie le mieux, selon lui, l’ontologie et l’épistémologie pour proposer un dialogue voire une intégration entre science et théologie. Ce réalisme critique a ensuite été repris par d’autres scientifiques-théologiens notamment Peacocke et Polkinghorne avec quelques nuances qui sont ici analysées.
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  29. A network of triangles.Bet Figueras - 1999 - Topos 29:93-96.
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  30. Biomolecular archaeology: past, present and future.R. E. M. Hedges & B. C. Sykes - 1992 - In Hedges R. E. M. & Sykes B. C. (eds.), New Developments in Archaeological Science. pp. 267-283.
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  31. Expectation and judgment: towards a phenomenology of discrimination.Tris Hedges - 2024 - Continental Philosophy Review (1):1-23.
    In this paper, my aim is to develop a phenomenological understanding of discrimination from the perspective of the discriminator. Since early existential phenomenology, the phenomenon of discrimination has received a great deal of attention. While much of this work has focused on the experience of the discriminatee, recent scholarship has begun to reflect on the intentional structures on the side of the discriminator. In a contribution to this trend, I argue that our sense of what is (ab)normal plays a constitutively (...)
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  32. A kultura-fogalom vázlata a fiatal Lukács írásaiban.Kapocsi Erzsébet - 1983 - In László Hársing (ed.), Tanulmányok a fiatal Lukácsról. [Budapest]: Művelődési Minisztérium Marxizmus-Leninizmus Oktatási Főosztálya.
     
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  33.  23
    Substitutionary Narration in the Cinema?Inez Hedges - 1974 - Substance 3 (9):45.
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  34.  42
    The Placebo Effect and Its Implications.Dawson Hedges & Colin Burchfield - 2005 - Journal of Mind and Behavior 26 (3):161-180.
    Often regarded simply as a nuisance in clinical drug trials in which the aim is to separate drug response from placebo response in a statistically significant manner, the placebo response has important implications. These implications relate to the nature of illness, the study of non-specific factors in the treatment setting that are related to clinical improvement, methods of enhancing these non-specific sources of benefit, and the neurobiology that is associated with the placebo response. Specific sources of clinical improvement in medical (...)
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  35.  24
    Transplants for non-lethal conditions: a case against hand transplantation in minors.Charles E. Hedges & Philip M. Rosoff - 2018 - Journal of Medical Ethics 44 (10):661-665.
    Human allografts for life-threatening organ failure have been demonstrated to be lifesaving and are now considered to be standard of care for many conditions. Transplantation of non-vital anatomic body parts has also been accomplished. Hand transplantation after limb loss in adults has been shown to offer some promising benefits in both functional and psychological measures in preliminary studies. It has been suggested to expand eligibility criteria to include minors, with one such operation having already been performed. With this in mind, (...)
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  36. Discriminatory Types and Homogenising Relevances: A Schutzian Perspective on Oppression.Tris Hedges & Sabrina De Biasio - 2024 - Human Studies (4):1-22.
    In this paper, we draw on Alfred Schutz’s theoretical framework to better understand how oppression is enacted through discriminatory acts. By closely examining the role of typifications and relevances in our experience of others, and by supplementing this analysis with contemporary social scientific resources, we argue that a Schutzian perspective on oppression yields important phenomenological insights. We do this in three key steps. Firstly, we contextualise Equality and the Meaning Structure of the Social World within Schutz’s broader body of work, (...)
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  37. The Abnormality of Discrimination: A Phenomenological Perspective.Tristan Hedges - 2022 - Genealogy+Critique 8 (1):1-22.
    Over the years, phenomenology has provided illuminating descriptions of discrimination, with its mechanisms and effects being thematised at the most basic levels of embodiment, (dis)orientation, selfhood, and belonging. What remains somewhat understudied is the lived experience of the discriminator. In this paper I draw on Husserl's phenomenological account of normality to reflect on the ways in which we discriminate at the prereflective levels of perceptual experience and bodily being. By critically reflecting on the intentional structures undergirding discriminatory practices, I argue (...)
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  38. Reclaiming misandry from misogynistic rhetoric.Tris Hedges - 2024 - Feminist Review 136 (1):84-99.
    In recent years, misogyny has become a central concept in philosophy as well as an established concept in public discourse and political policy. But where is misogyny’s supposed counterpart, namely, misandry? In this paper I argue for an ameliorative analysis of "misandry", arguing that it can be reformulated in an effort to reclaim it from its misogynistic weaponisation. The term "misandry" is used almost exclusively as a misogynistic rhetorical device for attributing unjust anger, hatred, or other similar emotions to a (...)
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  39. Beyond Care?Nicki Hedge & Alison Mackenzie - 2012 - Journal of Philosophy of Education 46 (2):192-206.
    Care is a feature of all of our lives, all of the time. An analysis of Scotland's Curriculum for Excellence reveals that care and caring permeate complex dimensions of life in and after school and we ask here, if, on some accounts, care can do the work required of it. Acknowledging the significance of her contribution to care, we focus on the work of Nel Noddings suggesting that she pays insufficient attention to other emotions implicated in the work of morally (...)
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  40.  12
    The Future of Love: Essays in Political Theology. By JohnMilbank. Pp. xxii, 382, London, SCM, 2009, £25.00. [REVIEW]Paul Hedges - 2015 - Heythrop Journal 56 (3):506-508.
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  41. Discriminatory Types and Homogenising Relevances: A Schutzian Perspective on Oppression.Tris Hedges & Sabrina De Biasio - 2024 - Human Studies 47 (4):727-748.
    In this paper, we draw on Alfred Schutz’s theoretical framework to better understand how oppression is enacted through discriminatory acts. By closely examining the role of typifications and relevances in our experience of others, and by supplementing this analysis with contemporary social scientific resources, we argue that a Schutzian perspective on oppression yields important phenomenological insights. We do this in three key steps. Firstly, we contextualise _Equality and the Meaning Structure of the Social World_ within Schutz’s broader body of work, (...)
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  42.  22
    La relation entre science et théologie et l’utilisation du réalisme critique.Estelle Poirot-Betting - 2020 - Revue des Sciences Philosophiques Et Théologiques 103 (1):23-41.
    L’article a pour objectif de rendre compte du réalisme critique introduit par le théologien Ian Barbour afin d’établir un « pont » entre science et théologie. Nous verrons pourquoi et comment Ian Barbour utilise cette philosophie qui relie le mieux, selon lui, l’ontologie et l’épistémologie pour proposer un dialogue voire une intégration entre science et théologie. Ce réalisme critique a ensuite été repris par d’autres scientifiques-théologiens notamment Peacocke et Polkinghorne avec quelques nuances qui sont ici analysées.
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  43.  15
    We and us: The power of the third for the first‐person plural.Tris Hedges - forthcoming - European Journal of Philosophy.
    Phenomenological discussions of sociality have long been concerned with the relations between the I, the You, and the We. Recently, dialogue between phenomenology and analytic philosophical work on collective intentionality has given rise to a corpus of literature oriented around the first-person plural “we.” In this paper, I demonstrate how these dominant accounts of the “we” are not exhaustive of first-person plural experiences as such. I achieve these aims by arguing for a phenomenological distinction between an experience of being part (...)
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  44.  12
    World cinema and cultural memory.Inez Hedges - 2015 - New York, NY: Palgrave-Macmillan.
    Cinema has long played a crucial role in the way that societies remember and represent themselves. In the last quarter century, film has been an important medium in the public debate around the memory of the Holocaust and of Hiroshima; of the Algerian war for independence and of the Spanish Civil War; of the Allende legacy in Chile, the utopian dreams of 1968, and the aborted project of the German Democratic Republic; in identity formation in Palestine and in the African (...)
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  45. We and us: The power of the Third for the first-person plural.Tris Hedges - 2023 - European Journal of Philosophy:1-14.
    Phenomenological discussions of sociality have long been concerned with the relations between the I, the You, and the We. Recently, dialogue between phenomenology and analytic philosophical work on collective intentionality has given rise to a corpus of literature oriented around the first-person plural 'we'. In this paper, I demonstrate how these dominant accounts of the 'we' are not exhaustive of first-person plural experiences as such. I achieve these aims by arguing for a phenomenological distinction between an experience of being part (...)
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  46.  36
    The Two Aesthetics of Haut Mal.Pierre Chappuis & Inez Hedges - 1975 - Substance 4 (11/12):101.
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  47.  63
    International students, export earnings and the demands of global justice.Penny Enslin & Nicki Hedge - 2008 - Ethics and Education 3 (2):107-119.
    Is it just to charge international students fees that are generally much higher than those paid by home and European Union students at UK universities? Exploring the ethical tension between universities? avowed commitment to social justice on the one hand and selling education to foreign students at a premium on the other, we argue that increased global association and the reduced salience of the sovereign state make the education of international students an issue of global justice. If we view education (...)
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  48. Luminescence and radiocarbon dating at Oxford= Datation par luminescence et radiocarbone a Oxford.R. E. M. Hedges, P. B. Pettitt & M. S. Tite - 1997 - Techne: Vers Une Science de l'Heritage Culturel: Quelques Exemples de Laboratoires Etrangers= Techne: Towards a Science for Cultural Legacy: Some Examples From Laboratories Outside France 5:54-60.
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  49.  11
    The research values of policy analysts.David M. Hedge & Jin W. Mok - 1989 - Knowledge, Technology & Policy 2 (1):21-41.
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  50.  36
    Categories and particulars: Prototype effects in estimating spatial location.Janellen Huttenlocher, Larry V. Hedges & Susan Duncan - 1991 - Psychological Review 98 (3):352-376.
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