In this dissertation, I develop and defend a model of causation that allows for dualist mental causation in worlds where the physical domain is physically complete. In Part I, I present the dualist ontology that will be assumed throughout the thesis and identify two challenges for models of mental causation within such an ontology: the exclusion worry and the common cause worry. I also argue that a proper response to these challenges requires a thoroughly lightweight account of causation, i.e. an (...) account that allows for causes to be metaphysically distinct from the phenomena that produce or physically necessitate their effects. In Part II, I critically evaluate contemporary responses to these challenges from the philosophical literature. In particular, I discuss List and Stoljar’s criticism of exclusion worries, Kroedel’s alternative dualist ontology, concerns about the notion of causal sufficiency, and Lowe’s models of dualist mental causation. I argue that none of these proposals provide independent motivation for a thoroughly lightweight account of causation and therefore leave room for improvement. In the first four chapters of Part III, I develop a thoroughly lightweight model of causation, which builds on interventionist approaches to causation. First, I explain how so-called ‘holding fixed’-requirements in standard interventionist accounts stand in the way of dualist mental causation. I then argue that interventionist accounts should impose a robustness condition on causal correlations and that, with this condition in place, the ‘holding fixed’-requirements can be weakened such that they do allow for dualist mental causation. I dub the interventionist model with such weakened ‘holding fixed’-requirements ‘insensitive interventionism’, argue that it can counter the exclusion worry as well as the common cause worry, and explain under which circumstances it would predict there to be dualist mental causation. Importantly, these circumstances might, for all we know, hold in the actual world. In the final three chapters of Part III, I defend insensitive interventionism against some objections. I consider the objection that causation must be productive, the objection that causes must physically necessitate their effects, and the objection that insensitive interventionism is too permissive. I respond by drawing from the literature on causation by absences and on the relation between causation and fundamental physics. Overall, insensitive interventionism performs as well as standard interventionist accounts. I conclude that insensitive interventionism is a credible model of causation. (shrink)

La notion de causalité repose sur une grande prétention : rendre intelligibles l’origine, la constitution et le devenir du monde. On lui attribue donc une portée universelle : tout événement a une cause. La majeure partie des débats philosophiques sur la causalité a concerné nos jugements intuitifs selon deux types de conceptions causales, soit la conception probabiliste et la conception processuelle. Chacune d’elles fait face à d’importants obstacles conceptuels dont les principaux sont la préemption, l’inaboutissement, la déconnexion et la méconnexion. (...) Or, afin de rendre compte de certains phénomènes physiques et d’éviter le problème classique des régularités fallacieuses – comme quoi, par exemple, la chute du baromètre ne saurait être la cause de la tempête – l’approche processuelle est généralement privilégiée. Max Kistler, entre autres, offre ainsi une théorie causale processuelle basée sur la notion de transfert d’énergie. Cependant, les cas paradigmatiques d’intrication quantique imposent de sérieuses contraintes aux approches processuelles, dont celle de Kistler. (shrink)

This paper studies the causal interpretation of counterfactual sentences using a modifiable structural equation model. It is shown that two properties of counterfactuals, namely, composition and effectiveness, are sound and complete relative to this interpretation, when recursive (i.e., feedback-less) models are considered. Composition and effectiveness also hold in Lewis's closest-world semantics, which implies that for recursive models the causal interpretation imposes no restrictions beyond those embodied in Lewis's framework. A third property, called reversibility, holds in nonrecursive causal (...) models but not in Lewis's closest-world semantics, which implies that Lewis's axioms do not capture some properties of systems with feedback. Causal inferences based on counterfactual analysis are exemplified and compared to those based on graphical models. (shrink)

Modern fundamental science tends to avoid the principle of physical causality and realism, replacing it with heuristically postulated and separated mathematical constructions that impose their own rules before being adjusted to measurement results. While it is officially accepted as the single possible kind of rigorous knowledge, we argue that another, explicitly extended kind of science can provide the causally complete picture of reality avoiding the glaring gaps, growing problems and persisting stagnation of the artificially reduced knowledge paradigm. The logic of (...) science development and especially its current state call for the urgently needed transition to the extended, causally complete kind of knowledge and related sustainable progress at superior creativity levels of self-aware, reason-based society. (shrink)

The causal set programme towards a quantum theory of gravity is situated vis-à-vis the long-standing debate between eternalism (block theory) and past-presentism or possibilism (growing block theory) in the philosophy of time. It is argued that despite 'appearances' and declarations to the contrary, the programme does not side with growing block theorists when it comes to harboring a robust notion of Becoming - at least, not more than familiar relativistic theories on continuous spacetime manifolds. The problem stems mainly from (...) the postulate of discrete general covariance - a requirement imposed upon the only fully worked out kind of dynamics for causal sets to date, a dynamics of a classical stochastic process. (shrink)

John Foster presents a clear and powerful discussion of a range of topics relating to our understanding of the universe: induction, laws of nature, and the existence of God. He begins by developing a solution to the problem of induction - a solution whose key idea is that the regularities in the workings of nature that have held in our experience hitherto are to be explained by appeal to the controlling influence of laws, as forms of natural necessity. His second (...) line of argument focuses on the issue of what we should take such necessitational laws to be, and whether we can even make sense of them at all. Having considered and rejected various alternatives, Foster puts forward his own proposal: the obtaining of a law consists in the causal imposing of a regularity on the universe as a regularity. With this causal account of laws in place, he is now equipped to offer an argument for theism. His claim is that natural regularities call for explanation, and that, whatever explanatory role we may initially assign to laws, the only plausible ultimate explanation is in terms of the agency of God. Finally, he argues that, once we accept the existence of God, we need to think of him as creating the universe by a method which imposes regularities on it in the relevant law-yielding way. In this new perspective, the original nomological-explanatory solution to the problem of induction becomes a theological-explanatory solution.The Divine Lawmaker is bold and original in its approach, and rich in argument. The issues on which it focuses are among the most important in the whole epistemological and metaphysical spectrum. (shrink)

For many philosophers, the relation of medicine to health is exemplary for understanding the relation of human power to nature in general. Drawing on Heidegger and Aquinas, this paper examines the relation of art to nature as it emerges in the second book of Aristotle’s Physics, and it does so by articulating the duality of efficient causality. The art of medicine operates as a dispositive cause rather than as a perfective cause; it removes obstacles to the achievement of health, but (...) it does not impose health. Medicine, on this conception, aids the efficient causality of the natural body rather than substituting for it. The loss of dispositive causality makes efficient causality an imposition of force that bypasses the natural power to achieve natural goods. The paper concludes, with Plato, by arguing that dispositive causality offers a way to understand not only medicine but also governing, teaching, and parenting. (shrink)

The legitimacy of going back to the classical view of God’s action in the world based on the list of causes and understanding of chance in the works of Aristotle and Aquinas – in the context of contemporary science – seems to depend on whether there is a space for causal analysis within the current models of scientific explanation. This article offers a brief account of the path leading to negation and rediscovery of the importance of causality in scientific (...) explanation and reintroduces the semicausal position of the prominent philosopher of science, Mario Bunge, who treats causation as one of several categories of determination. The diversity of the categories he lists finds analogy in the commonly accepted pluralist approach to the search of the model which adequately describes the practice of scientific research. What is more, the same diversity of the categories of determination opens the way back to the classical Aristotle’s fourfold account of causation and his understanding of chance. This fact allows us, in turn, to defend the contemporary version of the classical notion of divine action against the accusation of methodical error in the form of imposing the notion of the ancient categories of causality on the results of contemporary scientific research, which notion, as some maintain, has little in common with the models of explanation currently accepted in natural sciences. (shrink)

There is widespread belief in a tension between quantum theory and special relativity, motivated by the idea that quantum theory violates J. S. Bell’s criterion of local causality, which is meant to implement the causal structure of relativistic space-time. This paper argues that if one takes the essential intuitive idea behind local causality to be that probabilities in a locally causal theory depend only on what occurs in the backward light cone and if one regards objective probability as (...) what imposes constraints on rational credence along the lines of David Lewis’ Principal Principle, then one arrives at the view that whether or not Bell’s criterion holds is irrelevant for whether or not local causality holds. The assumptions on which this argument rests are highlighted, and those that may seem controversial are motivated. (shrink)

The invariance under interventions –account of causal explanation imposes a modularity constraint on causal systems: a local intervention on a part of the system should not change other causal relations in that system. This constraint has generated criticism against the account, since many ordinary causal systems seem to break this condition. This paper answers to this criticism by noting that explanatory models are always models of specific causal structures, not causal systems as a whole, (...) and that models of causal structures can have different modularity properties which determine what can and what cannot be explained with the model. (shrink)

Recent, well-publicized accounting scandals have shown that the penalties outsiders impose on those found culpable of earnings management can be severe. However, less is known about how colleagues within internal labor markets respond when they believe fellow managers have managed earnings. Designers of responsibility accounting systems need to understand the reputational costs managers impose on one another within internal labor markets. In an experimental study, 159 evening MBA students were asked to assume the role of a manager in a company (...) and respond to a scenario in which another manager (the target manager) has the opportunity to engage in earnings management. Participants provided causal attributions, assessed the morality of the target manager, and indicated whether they would change their judgments about the target manager's reputation. The study manipulated three between-subjects factors: (1) whether the target manager chose to engage in earnings management, (2) whether the company's budgetary control system was rigid or flexible, and (3) whether the target manager's work history was average or above average. We found that causal attributions are affected more by the budgetary systems when the target did not manage earnings than when the manager did. We also found that morality judgments were significantly associated with the target manager's behavior, but not with the budgetary system. In addition, participants' judgments about the target manager's reputation were more strongly associated with morality judgments than with causal attributions. We discuss implications of the role of reputation in management control systems design. (shrink)

This paper presents a formalism that combines useful properties of both logic and probabilities. Like logic, the formalism admits qualitative sentences and provides symbolic machinery for deriving deductively closed beliefs and, like probability, it permits us to express if-then rules with different levels of firmness and to retract beliefs in response to changing observations. Rules are interpreted as order-of-magnitude approximations of conditional probabilities which impose constraints over the rankings of worlds. Inferences are supported by a unique priority ordering on rules (...) which is syntactically derived from the knowledge base. This ordering accounts for rule interactions, respects specificity considerations and facilitates the construction of coherent states of beliefs. Practical algorithms are developed and analyzed for testing consistency, computing rule ordering, and answering queries. Imprecise observations are incorporated using qualitative versions of Jeffrey's rule and Bayesian updating, with the result that coherent belief revision is embodied naturally and tractably. Finally, causal rules are interpreted as imposing Markovian conditions that further constrain world rankings to reflect the modularity of causal organizations. These constraints are shown to facilitate reasoning about causal projections, explanations, actions and change. (shrink)

Quantal penetration through a (stationary) one-dimensional potential barrier is considered as a time evolution of an initially prepared wave packet. The large-time asymptotics of the process is concerned. Locality of the potential imposes certain analytical properties of the interaction amplitudes in the energy representation. The results are presented in terms of development of the phase-space (Wigner's) quasi-distribution. The phase-space evolution kernel is constructed, and it is shown that in the presence of a positive potential no part of the distribution is (...) transported faster than the free particle. For the case of a small initial momentum uncertainty, the deformation of the coordinate density is considered, including a possible advance of its maximum, which would not mean any noncausal signal transport. (shrink)

A common line of argument for the impossibility of closed causal loops is that they would involve causal paradoxes. The usual reply is that such loops impose heavy consistency constraints on the nature of causal connections in them; constraints that are overlooked by the impossibility arguments. Hugh Mellor has maintained that arguments for the possibility of causal loops also overlook some constraints, which are related to the chances (single-case, objective probabilities) that causes give to their effects. (...) And he argues that a consideration of these constraints demonstrates that causal loops are impossible. I consider Mellor's argument and more generally the nature of chance in causal loops. I argue that Mellor's line of reasoning is unwarranted since it is based on untenable premisses about the relation between chances and long-run frequencies in causal loops. Yet, this line of reasoning may still be of interest to those who maintain that causes determine the chances of their effects; for it raises some unresolved questions about the nature of chance in causal loops. (shrink)

This paper explores the origins of the term "causa sine qua non" used by Durand de Saint-Pourçain to describe the role of material things in knowledge. I show that its technical meaning comes from the Stoics and was transmitted to the Middle Ages by Boethius' commentary on Cicero's Topics. The expression "sine qua non" here does not have the ordinary and restricted meaning of "indispensable", "necessary condition", which can also apply to direct, per se causes of an effect. In the (...) present context, sine qua non causes do not act on the effect in question, either as concomitant, secondary, or instrumental causes, or as remote causes. They act only on that which hinders the actualization of a potentiality, in order to remove that obstacle. For example, the removal of a support that prevented something from falling does not act on that thing, nor does it add anything to its tendency to fall; it simply enables that thing to exercise its own actualization. Similarly, in cognitive processes, external things do not impose anything on the soul, but simply give it the opportunity to actualize its faculties of its own accord. I situate Durand's use of this form of causality in the context of late 13th/early 14th century theories of cognition, among several other attempts to find an alternative theory to the standard Aristotelian model and to maintain the pure activity of the soul with respect to the body. (shrink)

I argue that our traditional conception of the duties imposed by human rights is unable to acknowledge the nature of many contemporary human rights violations. The traditional conception is based on a broadly deontological view according to which human rights impose primarily negative and perfect duties, and these duties are held to be specific prohibitions on certain kinds of actions . I argue that given this conception of the nature of the duties imposed by human rights, not only claims to (...) aid, but in addition, claims against many of the most serious and prevalent contemporary active harms will not count as genuine human rights claims. These harms increasingly result from extremely complex causal chains involving the behaviour of a huge number of agents, few or none of whom can be singled out as responsible for a serious harm to any specific victim. Institutional structures can have just as central a role to play in specifying and allocating responsibility for fulfilling many of the negative duties imposed by human rights as the positive duties. These structures can therefore be equally important in the realisation of both kinds of rights. Before the necessary institutional reforms have taken place, both kinds of rights are equally genuine, and ground the imperative of justice to reform existing social institutions. (shrink)

The purpose of this paper is to explore the use of van Hees and Braham’s conception of causal responsibility in terms of NESS-conditions in formal models of collective action; NESS means ‘Necessary Element of a Sufficient Set’. In particular, the paper looks at their dictatorship result which arises from imposing uniformresponsibility on game forms which are augmented with a probabilistic component. Analogs for uniform NESS-responsibility are formulated within Belnap et al.’s stit models of agency—for both the instantaneous and (...) past-looking versions. In the case of instantaneous stit theory, NESS-responsibility has dstit as a special case, and the probabilistic component is unnecessary for deriving a full dictatorship result. For pastlooking agency, NESS-responsibility has astit as a special case, but uniformity, while not dictatorial, is shown to have a counterintuitive necessary condition: busy choosers. (shrink)

The key idea of the interventionist account of causation is that a variable A causes a variable B if and only if B would change if A were manipulated in the appropriate way. This paper raises two problems for Woodward's (2003) version of interventionism. The first is that the conditions it imposes are not sufficient for causation, because these conditions are also satisfied by non-causal relations of nomological dependence expressed in association laws. Such laws ground a relation of mutual (...) manipulability that is incompatible with the asymmetry of causation. Several ways of defending the interventionist account are examined and found unsatisfying. The second problem is that it often seems to be impossible, in a model that contains variables linked by an association law, to satisfy the conditions imposed on interventions on such variables. Various ways to solve this second problem, most importantly the analysis of manipulability in terms of difference making, are examined. Given that none solves the problem, I conclude that the interventionist conditions are neither sufficient nor necessary for causation. It is suggested that they provide an analysis of nomological dependence, which may be supplemented with the notion of a causal process to yield an analysis of causation. (shrink)

The causal structure of Darwinian evolution by natural selection is investigated. Its basic scheme is reproduction resulting from a feedback loop driven by internal and external causes. Causation internal to the loop connects genotype, development, phenotype, and fitness, with environmental constraints on the latter preventing runaway reproduction. External causes driving the core loop are environmental change and genetic change. This basic causal structure is complicated by modern additions such as control of mutation rate, niche construction, interactions between evolution (...) and development, and epigenetic effects. In this article it is argued that at least one of these additions, control of mutation rate, produces an additional feedback loop incorporating a continual, targeted modulation of stochasticity, and thereby produces an unusual form of causation. This form of causation entangles deterministic and stochastic causation in such a way that it imposes, in effect, an active, goal-driven role on the organisms in a line of descent. The goal is defined by the factor driving the stochasticity, which must be regarded as an intrinsic estimate made implicitly by the organism of its own fitness. The estimator itself is an evolved property of the organism, and is aligned with the apparent goal-directedness of natural selection. (shrink)

The (dis)continuism debate in the philosophy and cognitive science of memory concerns whether remembering is continuous with episodic future thought and episodic counterfactual thought in being a form of constructive imagining. I argue that settling that dispute will hinge on whether the memory traces (or “engrams”) that support remembering impose arational, perception-like constraints that are too strong for remembering to constitute a kind of constructive imagining. In exploring that question, I articulate two conceptions of memory traces—the replay theory and the (...) prop theory—that return conflicting answers to whether remembering is constructive imagining. The prop theory’s vision of traces is suggestive of continuism, while the replay theory’s is a natural fit for discontinuism. Which view of traces is in fact correct remains undetermined by current empirical work. Nevertheless, it may already be possible to reach a compromise in the (dis)continuism debate, through the development of a conciliatory continuist causal theory. This view—only outlined here—accepts the continuism-friendly prop theory of traces, while still requiring that genuine remembering fulfills an appropriate causation condition, as required by the kinds of causal theories of remembering typically favored by discontinuists. (shrink)

This paper argues that machine learning and epidemiology are on collision course over causation. The discipline of epidemiology lays great emphasis on causation, while ML research does not. Some epidemiologists have proposed imposing what amounts to a causal constraint on ML in epidemiology, requiring it either to engage in causal inference or restrict itself to mere projection. We whittle down the issues to the question of whether causal knowledge is necessary for underwriting predictions about the outcomes (...) of public health interventions. While there is great plausibility to the idea that it is, conviction that something is impossible does not by itself motivate a constraint to forbid trying. We disambiguate the possible motivations for such a constraint into definitional, metaphysical, epistemological, and pragmatic considerations and argue that “Proceed with caution” is the outcome of each. We then argue that there are positive reasons to proceed, albeit cautiously. Causal inference enforces existing classification schema prior to the testing of associational claims, but associations and classification schema are more plausibly discovered in a back-and-forth process of gaining reflective equilibrium. ML instantiates this kind of process, we argue, and thus offers the welcome prospect of uncovering meaningful new concepts in epidemiology and public health—provided it is not causally constrained. (shrink)

I will argue for the similarity between some aspects of Aristotle’s doctrine of causes and a particular kind of interventionist theory of causality. The interventionist account hypothesizes that there is a connection between causation and human intervention: the idea of a causal relation between two events is generated by the reflection of human beings on their own operating. This view is remindful of the Aristotelian concept of αἴτιον, which is linked to the figure of the αἴτιος, the person who (...) is responsible of an action. Aristotle conceives of the efficient cause as the active element which, in the φύσις, gives rise to movement and imposes the form, in analogy with the active element that in τέχνη operates the production: the craftsman. This analogy suggests that Aristotle conceives of the causation on the basis of the human ability to modify the environment with aims. Within the debate on the manipulative theory the classical accounts worked out by Collingwood, Gasking and von Wright have been recently criticized by Woodward. von Wright’s reductive account explains causation on the basis of human free action, while Woodward regards this reduction as a dangerous move which makes causal explanations too much anthropomorphic. I will show that Aristotle’s doctrine of causes is more similar to von Wright’s account and that the Aristotelian analysis of becoming supports von Wright’s reductive interventionism against Woodward’s criticism. Furthermore, I will draw a comparison between interventionism and dispositionalism, where the latter is another contemporary account of causation that claims Aristotelian roots. (shrink)

Despite the enormity of the financial losses flowing from the 2008 financial crisis and the outrageousness of the conduct that led up to it, almost no individual involved has been prosecuted for criminal conduct, much less actually gone to prison. What this chapter argues is that the failure to punish those in management for their role in this misconduct stems from a misunderstanding of the need to prove that they personally knew of this wrongdoing and harbored an intent to defraud. (...) But not only would negligence be a sufficient legal and moral basis for imposing terms of imprisonment in these cases, mere causal responsibility would also be enough, for causal responsibility has embed in it all we need to find those causally responsible morally responsible too, and once some basis for moral responsibility is established, the imposition of terms of imprisonment is both legally permitted and morally just. (shrink)

What is an epiphenomenal property? This question needs to be settled before we can decide whether higher-level properties are epiphenomenal or not. In this paper, I offer an account of what it is for a property to have some causal power. From this, I derive a characterisation of the notion of an epiphenomenal property. I then argue that physically realized higher-level properties are not epiphenomenal because laws of nature impose causal similarities on the bearers of such properties, and (...) these similarities figure as powers in the causal profiles of these properties. (shrink)

A combination of process and counterfactual theories of causation is proposed with the aim of preserving the strengths of each of the approaches while avoiding their shortcomings. The basis for the combination, or hybrid, view is the need, common to both accounts, of imposing a stability requirement on the causal relation.

The imposing scope and penetrating insights of German philosopher Nicolai Hartmann’s work have received renewed interest in recent years. The Neo-Kantian turned ontological realist established a philosophical approach unique among his peers, and it provides a wealth of resources for considering contemporary philosophical problems. The chapters included in this volume examine his ethics, ontology, aesthetics, philosophy of mind, and philosophy of nature. They explore his ontology of values, autonomy and human enhancement, and law; his theory of levels of reality, (...) space-time and geometry, the categories of temporality, causality, and “life,” the question of realism, and social ontology. Others take inspiration from his aesthetic theory, ideas about education,and his embrace of the Socratic pathos of wonder. They bring his philosophy into conversation with that of his contemporaries, including Roman Ingarden and Konrad Lorenz’s appropriation of Hartmann, as well as with the history of philosophy, including Plato’s theory of recollection, pre-Socratic philosophy, and that of his Russian teacher Nikolai Lossky. Those familiar with Hartmann’s wide-ranging systematic philosophy will benefit from these new engagements with his work, and those new to it will find them relevant to a number of current philosophical debates. (shrink)

The causal indeterminacy suggested by quantum mechanics has led to its being the centerpiece of several proposals for divine action that does not contradict natural laws. However, even if the theoretical concerns about the reality of causal indeterminacy are ignored, quantum-level divine action fails to resolve the problem of ongoing, responsive divine activity. This is because most quantum-level actions require a significant period of time in order to reach macroscopic levels whether via chaotic amplification or complete divine control (...) of quantum events. Therefore, quantum-level divine action either requires divine foreknowledge of purportedly free or random events or imposes such limitations on divine actions that they become late, potentially impotent, and confused. I argue that the theological problem of divine action remains; even at its most promising, quantum mechanics offers insufficient resolution. This failure suggests a reexamination of the assumptions that God is temporal and lacks foreknowledge of future contingencies. (shrink)

Causal decision theory produces decision instability in cases such as Death in Damascus where a decision itself provides evidence concerning the utility of options. Several authors have proposed ways of handling this instability. William Harper (1985 and 1986) advances one of the most elegant proposals. He recommends maximizing causal expected utility among the options that are causally ratifiable. Unfortunately, Harper's proposal imposes certain restrictions; for instance, the restriction that mixed strategies are freely available. To obtain a completely general (...) method of handling decision instability, I step outside the confines of pure causal decision theory. I introduce a new kind of backtracking expected utility and propose maximizing it among the options that are causally ratifiable. In other words, I propose a hierarchical maximization of (1) conditional causal expected utility and (2) the new backtracking expected utility. I support this proposal with some intuitive considerations concerning the distinction between optimality and conditional optimality. And I prove that the proposal yields a solution in every finite decision problem. (shrink)

The problem of collecting, analyzing and evaluating evidence on adverse drug reactions (ADRs) is an example of the more general class of epistemological problems related to scientific inference and prediction, as well as a central problem of the health-care practice. Philosophical discussions have critically analysed the methodological pitfalls and epistemological implications of evidence assessment in medicine, however they have mainly focused on evidence of treatment efficacy. Most of this work is devoted to statistical methods of causal inference with a (...) special attention to the privileged role assigned to randomized controlled trials in Evidence Based Medicine. Regardless of whether the RCT’s privilege holds for efficacy assessment, it is nevertheless important to make a distinction between causal inference of intended and unintended effects, in that the unknowns at stake are heterogonous in the two contexts. This point has been emphasized by epidemiologists in the last decade. Their main focus is methodological, and regards the fact that bias and confounding do not affect studies on intended and unintended effects in the same way. However, deeper concerns ground the intuition for such a distinction; these are related to the constraints which we impose on evidence and their epistemological justification. My thesis is that such constraints ought to be understood to be different in the case of evidence for risk vs. benefit assessment. I present the recent debate on the causal association between acetaminophen and asthma in order to illustrate the point at issue. (shrink)

Causation is a macroscopic phenomenon. The temporal asymmetry displayed by causation must somehow emerge along with other asymmetric macroscopic phenomena like entropy increase and the arrow of radiation. I shall approach this issue by considering ‘causal inference’ techniques that allow causal relations to be inferred from sets of observed correlations. I shall show that these techniques are best explained by a reduction of causation to structures of equations with probabilistically independent exogenous terms. This exogenous probabilistic independence imposes a (...) recursive order on these equations and a consequent distinction between dependent and independent variables that lines up with the temporal asymmetry of causation. (shrink)

Causation has always been a philosophically controversial subject matter. While David Hume’s empiricist account of causation has been the dominant influence in analytic philosophy and science during modern times, a minority view has instead connected causation essentially to agency and manipulation. A related approach has for the first time gained widespread popularity in recent years, due to new powerful theories of causal inference in science that are based in a technical notion of intervention, and James Woodward’s closely connected interventionist (...) theory of causation in philosophy. This monograph assesses five manipulationist or interventionist theories of causation, viewed as theories that purport to tell us what causation is by providing us with the meaning of causal claims. It is shown that they cannot do this, as the conditions on causation that they impose are too weak, mainly due to ineliminable circularities in their definitions of causal terms. It is then argued that a subset of Woodward’s theory can nevertheless contribute crucially to an explanation of the unique role that manipulation has in our acquisition of causal knowledge. This explanation differs from the common regularist explanation of the epistemic utility of manipulation and experiment, and it is taken to confirm several important manipulationist intuitions. However, the success of the explanation depends on (this subset of) interventionism not itself being understood as a theory of causation, but as a theory of intervention. (shrink)

The problem of collecting, analyzing and evaluating evidence on adverse drug reactions (ADRs) is an example of the more general class of epistemological problems related to scientific inference and prediction, as well as a central problem of the health-care practice. Philosophical discussions have critically analysed the methodological pitfalls and epistemological implications of evidence assessment in medicine, however they have mainly focused on evidence of treatment efficacy. Most of this work is devoted to statistical methods of causal inference with a (...) special attention to the privileged role assigned to randomized controlled trials in Evidence Based Medicine. Regardless of whether the RCT’s privilege holds for efficacy assessment, it is nevertheless important to make a distinction between causal inference of intended and unintended effects, in that the unknowns at stake are heterogonous in the two contexts. This point has been emphasized by epidemiologists in the last decade. Their main focus is methodological, and regards the fact that bias and confounding do not affect studies on intended and unintended effects in the same way. However, deeper concerns ground the intuition for such a distinction; these are related to the constraints which we impose on evidence and their epistemological justification. My thesis is that such constraints ought to be understood to be different in the case of evidence for risk vs. benefit assessment. I present the recent debate on the causal association between acetaminophen and asthma in order to illustrate the point at issue. (shrink)

Traditional moral theory usually has either of two emphases: virtuous moral character or principles for distributing duties or goods. “Zone morality” introduces a third: families and businesses are systems created by the causal reciprocities of their members. These relations embody the duties and permissions of a system's moral code. Core systems satisfy basic interests and needs; we move easily among them, hardly noticing that moral demands vary from system to system. Moral conflicts arise because of discord within or among (...) systems but also because morality has three competing sites: personal attitudes and practices (benevolence or hostility), the moral codes of systems, and regulative principles that enhance social cohesion. A strong church or central government reduces conflict by imposing its rules. A democracy responds by encouraging persons and systems to participate in forums where claims are made; it promises fairness by requiring that all satisfy its legal procedures. (shrink)

Physicalism is the default position in science and in the philosophy of mind, but it should not be, I argue, because of two errors. By its epistemological error, physicalism gives physics priority over the evidence of first person experience. Only what I experience in first person is certain, so observation is prior to any theory. Physics itself is based on observation, avoiding the epistemological error, and then physics can progress, even changing its own ontology. However, physicalism imposes the ontology of (...) physics on every science, and in physics everything is causal. By its ontological error, physicalism tries to explain causally what is intentional. And it happens that causality and intentionality are mutually exclusive, showing that the ontology of physics is insufficient wherever intentions are present. This ontological insufficiency prevents that physicalism can repeat the success of physics with any science where intentions play a rôle, and thus it is blocking the advance of both the social sciences and the philosophy of mind. To overcome this obstacle, I propose to go back to the essentials: we should consider again the transcendental problem raised by Descartes and its solutions by Hume and Kant. On top of this subjectivist solution, we should take advantage of Darwin and Turing, and we should extend our ontology beyond causality to include intentionality, and here my proposal is problem solving. Then you could join our Post-Kantian subjectivism and say with me: The world is not a huge machine, as physicalism proposes, but an enigmatic problem. (shrink)

Natural selection is commonly interpreted as the fundamental mechanism of evolution. Questions about how selection theory can claim to be the all-sufficient explanation of evolution often go unanswered by today's neo-Darwinists, perhaps for fear that any criticism of the evolutionary paradigm will encourage creationists and proponents of intelligent design.In Biological Emergences, Robert Reid argues that natural selection is not the cause of evolution. He writes that the causes of variations, which he refers to as natural experiments, are independent of natural (...) selection; indeed, he suggests, natural selection may get in the way of evolution. Reid proposes an alternative theory to explain how emergent novelties are generated and under what conditions they can overcome the resistance of natural selection. He suggests that what causes innovative variation causes evolution, and that these phenomena are environmental as well as organismal.After an extended critique of selectionism, Reid constructs an emergence theory of evolution, first examining the evidence in three causal arenas of emergent evolution: symbiosis/association, evolutionary physiology/behavior, and developmental evolution. Based on this evidence of causation, he proposes some working hypotheses, examining mechanisms and processes common to all three arenas, and arrives at a theoretical framework that accounts for generative mechanisms and emergent qualities. Without selectionism, Reid argues, evolutionary innovation can more easily be integrated into a general thesis. Finally, Reid proposes a biological synthesis of rapid emergent evolutionary phases and the prolonged, dynamically stable, non-evolutionary phases imposed by natural selection. (shrink)

What kind of epidemiological modeling works well? This is determined by the nature of the target: the relevant causal relations are unstable across contexts. I look at two influential examples of modeling from the Covid pandemic. The first is the paper from Imperial College London, which, in March 2020, was influential in persuading the UK government to impose a lockdown. Because it assumes stability, this first example of modeling fails. A different modeling strategy is required, one less ambitious but (...) more effective. This is illustrated by a second paper from Imperial College London, which, in December 2020, first estimated the transmissibility of the Alpha variant. (shrink)

Evolutionary biology distinguishes differences in survival and reproduction rates due to selection from those due to drift. The distinction is usually thought to be founded in probabilistic facts: a difference in (say) two variants' average lifespans over some period of time that is due to selection is explained by differences in the probabilities relevant to survival; in the purest cases of drift, by contrast, the survival probabilities are equal and the difference in lifespans is a matter of chance. When there (...) is a difference in actual average lifespans there is always a difference in causal histories, but in drift, the causal differences make no contribution to the relevant probabilities. Some writers have claimed that the framework that determines which causes contribute to the probabilities, and so the framework that determines when the relevant probabilities differ and when they are equal, is imposed by modelers rather than being an objective fact of nature, and so that the distinction between selection and drift, however practically useful, is unreal. This paper uses my work on biological probabilities (Bigger than Chaos) and probabilistic explanation (Depth) to argue for the objectivity of, and the importance of the objectivity of, the distinction between selection and drift. (shrink)

Does a person's liability to attack during a war depend on the nature of their individual causal contribution to the (unjust) threat posed? If so, how? The recent literature on the ethics of war has become increasingly focused on questions of this kind. According to some views on these matters, your liability hinges on the extent of your causal contribution: the larger your contribution to an unjust threat, the larger the amount of harm that we can impose on (...) you in order to avert the threat. Some philosophers have suggested that we can ground a quite general principle of civilian immunity on this basis. But, do causal contributions really come in degrees? Can we make sense of a graded notion of causal contribution that can be relevant to debates about liability in war? I argue there is good reason to be sceptical. The appearance that causal contributions come in degrees is just an illusion that can be explained away. (shrink)

A measure of good and bad is internal to something falling under it when that thing falls under the measure in virtue of what it is. The concept of an internal standard has broad application. Compare the external breed standards arbitrarily imposed at a dog show with the internal standards of health at work in the veterinarian's office. This paper is about practical standards, measures of acting well and badly, and so measures deployed in deliberation and choice. More specifically, it (...) is about the attempt to explain the unconditional validity of certain norms (say, of justice and prudence) by showing them to be internal to our agency and the causality it involves. This is constitutivism. Its most prominent incarnations share a set of assumptions about the nature of agency and our knowledge of it: conceptualism, formalism and absolutism. This essay investigates the merits and viability of rejecting all of them while still seeking the ground of practical normativity in what we are, in our fundamental activity. (shrink)

In a somewhat polemical article on ‘Solstices, Equinoxes, and the Presocratics’ D. R. Dicks has recently challenged the usual view that the Presocratics in general, and the Milesians in particular, made significant contributions to the development of scientific astronomy in Greece. According to Dicks, mathematical astronomy begins with the work of Meton and Euctemon about 430 B.C. What passes for astronomy in the earlier period ‘was still in the pre-scientific stage’ of ‘rough-and-ready observations, unsystematically recorded and imperfectly understood, of practical (...) men’ whose chief concern was to fix the seasons for ploughing, seed-time, sailing voyages and religious festivals. Ionian speculation, says Dicks, took very little note of such observation: ‘some of its wilder flights of fancy might have been avoided, if it had taken more’. In this account of the rise of Greek astronomy, the natural philosophers have no part to play. Their theories represent a speculative enterprise without a scientific future, a philosophic sideline with no impact on the development of observational science from Hesiod to Meton or the development of mathematical astronomy from Meton to Ptolemy.I believe that such a dichotomy between early philosophy and early science in Greece is misguided in principle, and that it seriously distorts our picture of the initial phases of each discipline. It also imposes a considerable strain upon our credulity. Take the case of Anaxagoras who, according to Plato and Theophrastus, had given a causal explanation of eclipses of the moon a generation before Meton. (shrink)

An important part of what it means for agents to be situated in the everyday world of human affairs includes their engagement with economic practices. In this paper, we employ the concept of cognitive institutions in order to provide an enactive and interactive interpretation of market and economic reasoning. We challenge traditional views that understand markets in terms of market structures or as processors of distributed information. The alternative conception builds upon the notion of the market as a “scaffolding institution.” (...) Introducing the concept of market as a “socially extended” cognitive institution we go beyond the notion of scaffolding to provide an enactive view of economic reasoning that understands the market participant in terms of social interactive processes and relational autonomy. Markets are more than inert devices for information processing; they can be viewed as “highly scaffolded,” where strong constraints and incentives predictably direct agents’ behavior. Building on this idea we argue that markets emerge from (a) the economic interaction of both supply and demand sides, in continual and mutual interplay, and (b) more basic social interactions. Consumer behavior in the marketplace is complex, not only contributing to determine the market price, but also extending the consumer’s cognitive processes to reliably attain a correct evaluation of the good. Moreover, this economic reasoning is socially situated and not something done in isolation from other consumers. From a socially situated, interactive point of view buying or not buying a good is something that enacts the market. This shifts the status of markets from external institutions that merely causally affect participants’ cognitive processes to social institutions that constitutively extend these cognitive processes. On this view the constraints imposed by social interactions, as well as the possibilities enabled by such interactions, are such that economic reasoning is never just an individual process carried out by an autonomous individual, classically understood. In this regard, understanding the concept of relational autonomy allows us to see how economic reasoning is always embodied, embedded in, and scaffolded by intersubjective interactions, and how such interactions make the market what it is. (shrink)

The building of a global model of carcinogenesis is one of modern biology’s greatest challenges. The traditional somatic mutation theory is now supplemented by a new approach, called the Tissue Organization Field Theory. According to TOFT, the original source of cancer is loss of tissue organization rather than genetic mutations. In this paper, we study the argumentative strategy used by the advocates of TOFT to impose their view. In particular, we criticize their claim of incompatibility used to justify the necessity (...) to definitively reject SMT. First, we note that since it is difficult to build a non-ambiguous experimental demonstration of the superiority of TOFT, its partisans add epistemological and metaphysical arguments to the debate. This argumentative strategy allows them to defend the necessity of a paradigm shift, with TOFT superseding SMT. To do so, they introduce a notion of incompatibility, which they actually use as the Kuhnian notion of incommensurability. To justify this so-called incompatibility between the two theories of cancer, they move the debate to a metaphysical ground by assimilating the controversy to a fundamental opposition between reductionism and organicism. We show here that this argumentative strategy is specious, because it does not demonstrate clearly that TOFT is an organicist theory. Since it shares with SMT its vocabulary, its ontology and its methodology, it appears that a claim of incompatibility based on this metaphysical plan is not fully justified in the present state of the debate. We conclude that it is more cogent to argue that the two theories are compatible, both biologically and metaphysically. We propose to consider that TOFT and SMT describe two distinct and compatible causal pathways to carcinogenesis. This view is coherent with the existence of integrative approaches, and suggests that they have a higher epistemic value than the two theories taken separately. (shrink)

Life scientists increasingly rely upon abstraction-based modeling and reasoning strategies for understanding biological phenomena. We introduce the notion of constraint-based reasoning as a fruitful tool for conceptualizing some of these developments. One important role of mathematical abstractions is to impose formal constraints on a search space for possible hypotheses and thereby guide the search for plausible causal models. Formal constraints are, however, not only tools for biological explanations but can be explanatory by virtue of clarifying general dependency-relations and patterning (...) between functions and structures. We describe such situations as constraint-based explanations and argue that these differ from mechanistic strategies in important respects. While mechanistic explanations emphasize change-relating causal features, constraint-based explanations emphasize formal dependencies and generic organizational features that are relatively independent of lower-level changes in causal details. Our distinction between mechanistic and constraint-based explanations is pragmatically motivated by the wish to understand scientific practice. We contend that delineating the affordances and assumptions of different explanatory questions and strategies helps to clarify tensions between diverging scientific practices and the innovative potentials in their combination. Moreover, we show how constraint-based explanation integrates several features shared by otherwise different philosophical accounts of abstract explanatory strategies in biology. (shrink)

This paper defends the Causal Theory of Reference against the recent criticism that it imposes a priori constraints on the aims and practices of science. The metaphysical essentialism of this theory is shown to be compatible with the requirements of naturalistic epistemology. The theory is nevertheless unable to forestall the problem of incommensurability for scientific terms, because it misrepresents the conditions under which their reference is fixed. The resources of the Causal Theory of Reference and of the traditional (...) cluster or "network" theory of meaning for handling problems of commensurability are compared, and an alternative approach is recommended. (shrink)

Every manifestation of information, semiosis and meaning we have been able to study experimentally has a physical form. Neglect of their dynamical (energetic) ground tends towards dualism or idealism, leaving the causal basis of semiosis and the causal powers of representations mysterious. Consideration of the necessary physical requirements for the embodiment of semiotic categories imposes a discipline on semiotics required for its integration into the rest of science, especially for the emerging field of biosemiotics, as well as any (...) future extensions to chemistry physics or other realms that might constitute a general, primal semiotics. Without this discipline, or something equally strong, there is a risk of projection of anthropomorphic semiotic terminology onto unsuitable hosts, leading, if unchecked, to the sort of animism that biology in particular has only recently escaped. The problem is suspect whenever teleological notions are used outside of mental or social contexts.1 Although our animistic ancestors may have had a closer rapport with Nature than modern scientists, contemporary scientific explanation requires an understanding of causal structure (Salmon 1984). On the other hand, unless the causal rendition of semiosis can capture full blown cognitive semiosis, it is likely to be too restrictive for the evaluation of primal semiosis in general. (shrink)

An algebraic interpretation of multigraph networks is introduced in relation to conscious experience, brain and body. These multigraphs have the ability to merge by an associative binary operator \(\odot \), accounting for biological composition. We also study a mathematical formulation of splitting layers, resulting in a formal analysis of the transition from conscious to non-conscious activity. From this construction, we recover core structures for conscious experience, dynamical content and causal constraints that conscious interactions may impose. An important result is (...) the prediction of structural topological changes after conscious interactions. These results may inspire further use of formal mathematics to describe and predict new features of conscious experience while aligning well with formal tries to mathematize phenomenology, phenomenological tradition and applications to artificial consciousness. (shrink)

This paper is centred around a debate taking place among environmental scientists. One camp argues that proof of a causal connection between a chemical and a biological anomaly must be demonstrated in the laboratory. The other contends that actual damage is underestimated in the lab, and that it is therefore necessary to conduct supplemental ecoepidemiological research in order to determine the full impact of toxic chemicals. Members of the former contingent – claiming to be defending scientific rigour – sometimes (...) accuse their peers of practising an inferior science. This paper argues that this contention is supported by a philosophical tradition tending to favour abstract and formal analysis over the close examination of material detail. To the extent that this preference has been adopted by the media, industry, policy analysts, and regulatory bodies, more is at stake than an intellectual squabble. The paper provides a brief overview of the history of the formalist tendency in philosophy, followed by an illustration of the ways in which advocates of a strict laboratory methodology implicitly rely on this foundation. The work and ideas of contemporary ecoepidemiologists are then compared to this imposing edifice of traditional science. (shrink)

I distinguish Nature from the World. I also distinguish development from evolution. Development is progressive change and can be modeled as part of Nature, using a specification hierarchy. I have proposed a ‘canonical developmental trajectory’ of dissipative structures with the stages defined thermodynamically and informationally. I consider some thermodynamic aspects of the Big Bang, leading to a proposal for reviving final cause. This model imposes a ‘hylozooic’ kind of interpretation upon Nature, as all emergent features at higher levels would have (...) been vaguely and episodically present primitively in the lower integrative levels, and were stabilized materially with the developmental emergence of new levels. The specification hierarchy’s form is that of a tree, with its trunk in its lowest level, and so this hierarchy is appropriate for modeling an expanding system like the Universe. It is consistent with this model of differentiation during Big Bang development to view emerging branch tips as having been entrained by multiple finalities because of the top-down integration of the various levels of organization by the higher levels. (shrink)

A robust, if not absolute, prohibition on treating people simply as a means sits at the core of common sense deontological morality. But the principle prohibiting such treatment, the "means principle" (MP), has been notoriously hard to defend. This paper has two parts. In Part I, I survey why the interpretation of the MP in terms of intentions does not work, and why the interpretation in terms of causes, as defended up to now, is so mysterious as to be question (...) begging. I also explore Judith Jarvis Thomson's early and admittedly failed attempt to explain the MP in terms of rights. In Part II, I articulate and defend a new account of a causal interpretation of the MP. The principle I defend there, the Restricting Claims Principle, registers the moral significance of the fact that certain claims have a kind of moral externality: if they had to be respected as rights that would restrict what agents could do on behalf of other patients. Claims that impose that sort of externality, restricting claims, register as less weighty than claims that do not. The claims of those who would be used simply as a means (a causal notion) are not restricting, and that explains why they are stronger than competing restricting claims. (shrink)

Sir Karl Popper is well known for explicating science in falsificationist terms, for which his degree of corroboration formalism, C(h,e,b), has become little more than a symbol. For example, de Queiroz and Poe in this issue argue that C(h,e,b) reduces to a single relative (conditional) probability, p(e,hb), the likelihood of evidence e, given both hypothesis h and background knowledge b, and in reaching that conclusion, without stating or expressing it, they render Popper a verificationist. The contradiction they impose is easily (...) explained--de Queiroz and Poe fail to take account of the fact that Popper derived C(h,e,b) from absolute (logical) probability and severity of test, S(e,h,b), where critical evidence, p(e,b), is fundamental. Thus, de Queiroz and Poe's conjecture that p(e,hb) = C(h,e,b) is refuted. Falsificationism, not verificationism, remains a fair description of the parsimony method of inference used in phylogenetic systematics, not withstanding de Queiroz and Poe's mistaken understanding that "statistical" probability justifies that method. Although de Queiroz and Poe assert that maximum likelihood has the power "to explain data", they do not successfully demonstrate how causal explanation is achieved or what it is that is being explained. This is not surprising, bearing in mind that what is assumed about character evolution in the accompanying likelihood model M cannot then be explained by the results of a maximum likelihood analysis. (shrink)