In this paper I investigate the relationship between vernacular kind terms and specialist scientific vocabularies. Elsewhere I have developed a defence of realism about the chemical elements as natural kinds. This defence depends on identifying the epistemic interests and theoretical conception of the elements that have suffused chemistry since the mid-eighteenth century. Because of this dependence, it is a discipline-specific defence, and would seem to entail important concessions to pluralism about natural kinds. I argue that making this kind of concession (...) does not imply that vernacular kind terms have independent application conditions. Nor does it preclude us saying that chemists, with their particular epistemic interests, have discovered the underlying nature of water, the stuff that is named and thought about in accordance with the practical interests of everyday life. There are limits to pluralism. (shrink)

A chemical substance is instantiated in the material world by a number of quantities of such substance, placed in different locations. A change of location implies a change in the net of relationships entertained by the QCS with the region wherein it is found. This fact entails changes of the ontological status of the CS, as this is not fully determined by the inherent features of the CS and includes a relevant relational contribution. In order to demonstrate this thesis, we (...) have chosen to analyse the status of quantities of a same CS that are synchronically located in different spacetime regions: a synthetic lab, a lab where the QCS is turned into a material, an industrial plant, the market where the QCS gets a price and a dump waste where the QCS is discarded, respectively: Chemical substance Open image in new window material Open image in new window product Open image in new window goods Open image in new window wasteThe use of first-order predicate logic, mereology and locative logic allows carrying out a regimentation process that highlights the ontological commitments implied by the formal expressions through which each element of the aforementioned series can be described. The presence of relational properties discloses the systemic nature of the CS instantiated within a spacetime region. The implications of such an aspect are discussed. (shrink)

The strategic use of disease and poison in warfare has been subject to a longstanding and cross-cultural taboo that condemns the hostile exploitation of poisons and disease as the act of a pariah. In short, biological and chemical weapons are simply not fair game. The normative opprobrium is, however, not fixed, but context dependent and, as a social phenomenon, remains subject to erosion by social (or more specifically, antisocial) actors. The cross cultural understanding that fighting with poisons and disease is (...) reprehensible, that they are taboo, is codified through a web of interconnected measures, principal amongst these are the 1925 Geneva Protocol; the Biological Weapons Convention; and the Chemical Weapons Convention. Whilst these treaties have weathered the storm of international events reasonably well, their continued health is premised on their being ‘tended to’ in the face of contextual changes, particularly facing changes in science and technology, as well as the changed nature and character of conflict. This article looks at the potential for normative erosion of the norm against chemical and biological weapons in the face of these contextual changes and the creeping legitimization of chemical and biological weapons. (shrink)

Chemistry is a highly technical field that relies heavily on a range of symbolic and imagic formalisms. These formalisms conceptualize specific chemical knowledge into semiotic resources that are rarely used elsewhere in most other academic fields or contexts. To develop an understanding of semiosis in highly technical fields such as chemistry, key questions include what this range of formalisms do and why they occur. These are key questions not only for our understanding of semiosis, but also if we wish to (...) develop integrated literacy programs that can support students to marshal the multimodal discourse of chemistry. This paper explores these questions by examining how three key chemical formalisms organize their meaning: symbolic formalisms known as chemical formulas and chemical equations, and an imagic formalism known as structural formulas. Drawing on Systemic Functional Linguistics and using a corpus of formalisms from secondary school chemistry, these formalisms are explored in terms of their overarching grammatical organization and the content meanings they realize through the concept of “field.” This is used to compare and contrast each formalism in terms of a semiotic typology so as to understand how they work and what meanings they realize. By exploring chemical formalisms in this way, this paper establishes a means of seeing the similarities and differences in meaning-making across formalisms and explaining why different formalisms occur. This then begins to provide a base upon which applied programs can interpret the literacy needs of chemistry. (shrink)

There is a persisting debate about what chemical bonds are and whether they exist. I argue that chemical bonds are real patterns of interactions between subatomic particles. This proposal resolves the problems raised in the context of existing understandings of the chemical bond and provides a novel way to defend the reality of chemical bonds.

Cellular reprogramming can manipulate the identity of cells to generate the desired cell types1– 3. The use of cell intrinsic components, including oocyte cytoplasm and transcription factors, can enforce somatic cell reprogramming to pluripotent stem cells4– 7. By contrast, chemical stimulation by exposure to small molecules offers an alternative approach that can manipulate cell fate in a simple and highly controllable manner8– 10. However, human somatic cells are refractory to chemical stimulation owing to their stable epigenome2,11,12 and reduced plasticity13,14; it (...) is therefore challenging to induce human pluripotent stem cells by chemical reprogramming. Here we demonstrate, by creating an intermediate plastic state, the chemical reprogramming of human somatic cells to human chemically induced pluripotent stem cells that exhibit key features of embryonic stem cells. The whole chemical reprogramming trajectory analysis delineated the induction of the intermediate plastic state at the early stage, during which chemical-induced dedifferentiation occurred, and this process was similar to the dedifferentiation process that occurs in axolotl limb regeneration. Moreover, we identified the JNK pathway as a major barrier to chemical reprogramming, the inhibition of which was indispensable for inducing cell plasticity and a regeneration-like program by suppressing pro-inflammatory pathways. Our chemical approach provides a platform for the generation and application of human pluripotent stem cells in biomedicine. This study lays foundations for developing regenerative therapeutic strategies that use well-defined chemicals to change cell fates in humans. (shrink)

The paper discusses how well Kuhn’s general theory of scientific revolutions fits the particular case of the chemical revolution. To do so, I first present condensed sketches of both Kuhn’s theory and the chemical revolution. I then discuss the beginning of the chemical revolution and compare it to Kuhn’s specific claims about the roles of anomalies, crisis and extraordinary science in scientific development. I proceed by comparing some features of the chemical revolution as a whole to Kuhn’s general account. The (...) result will be that Kuhn’s general description of scientific revolutions fits the chemical revolution extraordinarily well. However, this result should not be taken as an empirical confirmation of Kuhn’s theory, but rather as an indication that the chemical revolution is a constitutive part of it. (shrink)

From the perspective of successive events, chemical reactions are expressed or thought about, in terms of the cause-effect category. In this work, I will firstly discuss some aspects of causation and interaction in chemistry, argue for the interaction, and propose an alternative or complementary representation scheme called “interaction diagram”, that allows representing chemical reactions through a geometric diagram. The understanding of this diagram facilitates the analysis of reactions in terms of the interaction, or reciprocal action, among the participating entities. Secondly, (...) I will describe the model and provide examples and finally, I will discuss the scope and limitations of the current development status of the model. (shrink)

Environmental chemicals accumulate in all human bodies and have the potential to affect the health of men and women, adults, and children. This article advances “precautionary consumption”—the effort to mediate personal exposure to environmental chemicals through vigilant consumption—as a new empirical site for understanding the intersections between maternal embodiment and contemporary motherhood as a consumer project. Using in-depth interviews, I explore how a group of 25 mothers employ precautionary consumption to mediate their children’s exposure to chemicals found (...) in food, consumer products, and the home. Most of the mothers in the study situate their children’s chemical “burdens” within their own bodies and undertake the labor of precautionary consumption as part of a larger and commodity-based motherhood project. In actively expanding the sphere of responsible motherhood to include managing children’s body burdens, these mothers navigate multiple and overlapping contexts that hold women accountable for children’s futures and value the agency of the proactive consumer. Yet, as the sphere of responsible mothering expands, women without financial resources, time, and family stability are pushed to the margins of normative motherhood. (shrink)

What is it that turns a new observation into a true scientific discovery? And who may claim the credit? Theoreticians of science, the foremost thinkers of their times among them, have tried to answer these fundamental questions about the nature of scientific progress and discovery. With clear insight and the chemical as well as philosophical wisdom gained from over fifty years as a practising chemist, Jerome Berson puts their theories to the test. The development of chemistry into a "modern" science (...) during the last two centuries provides him with ample cases to illustrate the way scientific progress really happens. Kekul?'s struggle to arrive at a structure for benzene, the paradigm change that was necessary to accept the reality of molecular rearrangements, and other episodes are retold here from the philosopher's as well as from the practitioner's perspective, shedding light on the way scientists think and act. Berson's account of the rather unphilosophical way in which scientific discoveries are made includes the realization that even a false hypothesis, such as Woodward's ideas about the biosynthesis of strychnine, may help rather than hinder scientific progress. Scientists of all ages, as well as many non-scientists, will find this a highly readable and unusual book. (shrink)

Following Kripke and Putnam, the received view of chemical kinds has been a microstructuralist one. To be a microstructuralist about chemical kinds is to think that membership in said kinds is conferred by microstructural properties. Recently, the received microstructuralist view has been elaborated and defended, but it has also been attacked on the basis of complexities, both chemical and ontological. Here, I look at which complexities really challenge the microstructuralist view; at how the view itself might be made more complicated (...) in order to accommodate such challenges; and finally, at what this increasingly complicated picture implies for our standard assessment of chemical kindhood—primarily, for the widespread assumption that chemical kinds in general are more neat and tidy than those messy biological ones. _1_ The Received View _2_ A Taxonomy of Chemical Kinds _3_ Atomic Number _4_ H2O, H3O+, OH−, and More _5_ Complicating the Microstructuralist Picture _6_ Concrete and Other Mixtures _7_ Macromolecules, Especially Proteins _8_ Abandoning Sameness of Elemental Composition _9_ Not So Different after All. (shrink)

Long-standing neglect of the chemical senses in the philosophy of perception is due, mostly, to their being regarded as ‘lower’ senses. Smell, taste, and chemically irritated touch are thought to produce mere bodily sensations. However, empirically informed theories of perception can show how these senses lead to perception of objective properties, and why they cannot be treated as special cases of perception modelled on vision. The senses of taste, touch, and smell also combine to create unified perceptions of flavour. The (...) nature of these multimodal experiences and the character of our awareness of them puts pressure on the traditional idea that each episode of perception goes one or other of the five senses. Thus, the chemical senses, far from being peripheral to the concerns of the philosophy of perception, may hold important clues to the multisensory nature of perception in general. (shrink)

We have synthesized a 582,970-base pair Mycoplasma genitalium genome. This synthetic genome, named M. genitalium JCVI-1.0, contains all the genes of wild-type M. genitalium G37 except MG408, which was disrupted by an antibiotic marker to block pathogenicity and to allow for selection. To identify the genome as synthetic, we inserted "watermarks" at intergenic sites known to tolerate transposon insertions. Overlapping "cassettes" of 5 to 7 kilobases (kb), assembled from chemically synthesized oligonucleotides, were joined by in vitro recombination to produce intermediate (...) assemblies of approximately 24 kb, 72 kb ("1/8 genome"), and 144 kb ("1/4 genome"), which were all cloned as bacterial artificial chromosomes in Escherichia coli. Most of these intermediate clones were sequenced, and clones of all four 1/4 genomes with the correct sequence were identified. The complete synthetic genome was assembled by transformation-associated recombination cloning in the yeast Saccharomyces cerevisiae, then isolated and sequenced. A clone with the correct sequence was identified. The methods described here will be generally useful for constructing large DNA molecules from chemically synthesized pieces and also from combinations of natural and synthetic DNA segments. 10.1126/science.1151721. (shrink)

Kant conceives of chemical dissolutions as involving the infinite division and subsequent blending of solvent and solute. In the resulting continuous solution, every subvolume contains a uniform proportion of each reactant. Erich Adickes argues that this account stands in tension with other aspects of Kant’s Critical philosophy and his views on infinity. I argue that although careful analysis of Kant’s conception of dissolution addresses Adickes’ objections, the infinite division inherent to the process is beyond our human cognition, for Kant. Nevertheless, (...) such infinite division may be considered as an idea of reason to make comprehensible chemical reactions, revealing reason to play a pivotal role in the foundations of chemistry. (shrink)

The main scientific problems of chemical bonding were solved half a century ago, but adequate philosophical understanding of chemical combination is yet to be achieved. Chemists routinely use important terms ("element," "atom," "molecule," "substance") with more than one meaning. This can lead to misunderstandings. Eliminativists claim that what seems to be a baseball breaking a window is merely the action of "atoms, acting in concert." They argue that statues, baseballs, and similar macroscopic things "do not exist." When macroscopic objects like (...) baseballs move, exceedingly large numbers (1025) of microscopic components coordinate their activities. Understanding how this happens requires attention to the interactions that link parts into larger units. Eliminativists say that everything that truly exists has causal relationships in addition to those of its components—"nonredundant causality." This paper holds that if a number of entities interact in such a way that the effect of that collection on test objects is different than it would have been in the absence of the interaction, then identification of that collection as a single composite agent is warranted, for purposes to which that difference is relevant. Ordinary "chemical substances" (both elementary materials such as dihydrogen and compounds such as water) fulfill this version of the requirement of nonredundant causality. Other sorts of chemical coherences, including chemical dissipative structures (e.g., flames), also fulfill that criterion. All these types of coherences qualify as "substances" (as that term is used in philosophy) even though they are not all "chemical substances.". (shrink)

In several jurisdictions, sex offenders may be offered chemical castration as an alternative to further incarceration. In some, agreement to chemical castration may be made a formal condition of parole or release. In others, refusal to undergo chemical castration can increase the likelihood of further incarceration though no formal link is made between the two. Offering chemical castration as an alternative to further incarceration is often said to be partially coercive, thus rendering the offender’s consent invalid. The dominant response to (...) this objection has been to argue that any coercion present in such cases is compatible with valid consent. In this article, we take a different tack, arguing that, even if consent would not be valid, offering chemical castration will often be supported by the very considerations that underpin concerns about consent: considerations of autonomy. This is because offering chemical castration will often increase the offender’s autonomy, both at the time the offer is made and in the future. (shrink)

Friedrich Paneth’s conception of “chemical element” has functioned as the official definition adopted by the International Union of Pure and Applied Chemistry since 1923. Paneth maintains a distinction between empirical and “transcendental” concepts of element; furthermore, chemical science requires fluctuation between the two. The origin of the empirical-transcendental split is found in Immanuel Kant’s classic Critique of Pure Reason (1781/1787). The present paper examines Paneth’s foundational concept of element in light of Kant’s attempt, late in life, to revoke key distinctions (...) made in his Critique, including that of regulative and constitutive functions of reason. In a section of his Opus postumum devoted to the “Transition from the Metaphysical Foundations of Natural Science to Physics,” Kant bends his philosophical system to address the newly emerging sciences of matter of his time. Specifically, he tried, without success, to develop the transcendental ground for microscale motions of bodies encountered in physical, electrical and chemical processes. Paneth’s discussion of chemical element does not take the Opus postumum into account, which is why it begins with a rejection of Kant’s rejection (in his earlier writings) of chemistry’s status as science. I make the case that Paneth’s definition of element effectively maintains something very like Kant’s critical separation of regulative and constitutive principles, while a advancing the concept of chemical science. (shrink)

Late nineteenth‐century opponents of atomism questioned whether the evidence required any notion of an atom. In this spirit, Duhem developed an account of the import of chemical formulas that is clearly neutral on the atomic question rather than antiatomistic. The argument is supplemented with specific inadequacies of atomic theories of chemical combination and considerably strengthened by the theory of chemical combination provided by thermodynamics. Despite possible counterevidence available at the time, which should have tempered some of Duhem's concluding remarks, there (...) was no atomic theory of chemical combination, which is wholly a product of the twentieth century. †To contact the author, please write to: Department of Philosophy, University of Stockholm, SE‐106 91 Stockholm, Sweden; e‐mail: [email protected]. (shrink)

Despite the importance molecular structure has acquired in 20th century chemistry, more traditional macroscopic notions in terms of a continuous concept of matter continue to play a role in chemical theorising. In the light of the extensive and determined criticism of reductionism in recent philosophy of chemistry, it is of interest to see macroscopic ontology treated autonomously. One aspect of this is developed here, namely the concept of chemical substance. This is characterised by contrast with phases and solutions. The key (...) conception is that of an intensive property, which is defined by appeal to the mereological structure of parts of the entities bearing substance properties. (shrink)

The main scientific problems of chemical bonding were solved half a century ago, but adequate philosophical understanding of chemical combination is yet to be achieved. Chemists routinely use important terms with more than one meaning. This can lead to misunderstandings. Eliminativists claim that what seems to be a baseball breaking a window is merely the action of “atoms, acting in concert.” They argue that statues, baseballs, and similar macroscopic things “do not exist.” When macroscopic objects like baseballs move, exceedingly large (...) numbers of microscopic components coordinate their activities. Understanding how this happens requires attention to the interactions that link parts into larger units. Eliminativists say that everything that truly exists has causal relationships in addition to those of its components—“nonredundant causality.” This paper holds that if a number of entities interact in such a way that the effect of that collection on test objects is different than it would have been in the absence of the interaction, then identification of that collection as a single composite agent is warranted, for purposes to which that difference is relevant. Ordinary “chemical substances” fulfill this version of the requirement of nonredundant causality. Other sorts of chemical coherences, including chemical dissipative structures, also fulfill that criterion. All these types of coherences qualify as “substances” even though they are not all “chemical substances.”. (shrink)

The practice of medicine frequently involves the unconsented restriction of liberty. The reasons for unilateral liberty restrictions are typically that being confined, strapped down, or sedated are necessary to prevent the person from harming themselves or others. In this paper, we target the ethics of chemical restraints, which are medications that are used to intentionally restrict the mental states associated with the unwanted behaviors, and are typically not specifically indicated for the condition for which the patient is being treated. Specifically, (...) we aim to identify the conditions under which chemical restraints are ethically permissible. It is wrong to assume that what is morally true of physical restraints is also true of chemical restraints. Our aim is thus to identify the conditions under which chemical restraints are permissible while distinguishing these conditions from those of the application of physical restraints. (shrink)

SummaryThis essay explains why and how nineteenth-century chemists sought to stabilize the melting and boiling points of organic substances as reliable characteristics of identity and purity and how, by the end of the century, they established these values as ‘Constants of Nature’. Melting and boiling points as characteristic values emerge from this study as products of laboratory standardization, developed by chemists in their struggle to classify, understand and control organic nature. A major argument here concerns the role played by the (...) introduction of organic synthesis in driving these changes. Synthetic organic chemistry vastly increased the number of known organic substances, precipitating the chemical identity crisis of my title. Successful natural product synthesis, moreover, depended on chemists’ ability to demonstrate the absolute identity of synthetic product and natural target – something late nineteenth-century chemists eventually achieved by making reliable, replicable melting and boiling point measurements. In the period before the establishment of national standards laboratories, chemists and scientific glassblowers worked together to standardize melting and boiling points as physical constants, such collaborations highlighting the essential importance of chemical glassware and glassblowing skill in the development of nineteenth-century organic chemistry. (shrink)

The ArgumentThe overall portrayal of early modern experimentation as a new method of securing assent within a philosophical discourse sketched in many of the recent studies on the historical origin of experimentation is questioned by the analysis of the experimental practice of chemistry at the Paris Academy. Chemical experimentation at the Paris Academy in the late seventeenth and early eighteenth century originated in a different tradition than the philosophical. It continued and developed the material culture of the chemical work shops (...) of the sixteenth and seventeenth centuries, and explored epistemic objects which had rather loose connections to philosophy. On the other hand, I argue against the classical dichotomy between the work of the mind that of the hand, and for an epistemology of experimentation that acknowledges that experimental manipulation goes hand in hand with reflexion. In particuler, I argue against the view that chemists at the Paris Academy were “pragmatists” who merely gathered experimental facts and classified substances and operations without perplexing themselves over general conceptions. I claim that the chemists at the Paris Academy constructed a general conception framework which shaped the significance of their experiments. This conception that I call conception of the chemical combination, compound and reaction was rather quickly reified into an experimental fact. Despite its generality it was a genuine chemical conception rather independent of philosophy. (shrink)

Given the rich diversity of research fields usually ascribed to chemistry in a broad sense, the present paper tries to dig our characteristic parts of chemistry that can be conceptually distinguished from interdisciplinary, applied, and specialized subfields of chemistry, and that may be called chemistry in a very narrow sense, or 'the chemical core of chemistry'. Unlike historical, ontological, and 'anti-reductive' approaches, I use a conceptual approach together with some methodological implications that allow to develop step by step a kind (...) of cognitive architecture for chemistry, which basically contains: (1) systematic chemical knowledge on the experimental level; (2) clarification of chemical species; (3) chemical classification systems; (4) theoretical foundation through the chemical theory of structural formulas. In a succeeding paper the results will be checked for resisting physicalistic reduction. (shrink)

PDF version As a scientific productive activity, engineering is closely associated with natural science on the one hand and industry on the other. The emergence of chemical engineering was influenced by the America’s industrial structures and academic institutions. The science-oriented characteristic of chemical engineering in turn impacted the development of industrial structures, especially the rapid rise of a competitive petrochemical industry.

Patterns resulting from the sole interplay between reaction and diffusion are probably involved in certain stages of morphogenesis in biological systems, as initially proposed by Alan Turing. Self-organization phenomena of this type can only develop in nonlinear systems (i.e. involving positive and negative feedback loops) maintained far from equilibrium. We present Turing patterns experimentally observed in a chemical system. An oscillating chemical reaction, the CIMA reaction, is operated in an open spatial reactor designed in order to obtain a pure reaction-diffusion (...) system. The two types of Turing patterns observed, hexagonal arrays of spots and parallel stripes, are characterized by an intrinsic wavelength. We identify the origin of the necessary difference of diffusivity between activator and inhibitor. We also describe a pattern growth mechanism by spot splitting that recalls cell division. (shrink)

In this essay, the first statistical and stochastic treatments of chemical dynamics are analyzed and discussed, in particular the diffusive description of chemical reactions. The first part of the paper introduces the historical and methodological basis of the theories about stochastic processes and diffusion as well as their lesser-known applications in chemical kinetics, which were advanced by Jens Anton Christiansen (1888–1969). In the second, part we will focus our attention on the early works of Oskar Benjamin Klein (1894–1977) and Hendrik (...) Anton Kramers (1894–1952) on electrolytes and the latter’s more mature work, which completes and gives a firm theoretical background to Christiansen’s description. (shrink)

This paper surveys some ways in which the chemical realm can be described and outlined in terms of the concept of supervenience. The particular contours of general chemical theory provide a ready basis for interpretation of determination, covariance, and nonreduction—the characteristic metaphysical facets of the supervenience relation—in mutual terms. Building on this, the extent to which chemically characterized properties and entities can be described in terms of a supervenience-scaffolded structure represents a particularly vivid application that philosophers in general interested in (...) supervenience would do well to attend to. In addition, the model of chemical supervenience given here can be used as a rubric on which to decide on issues already raised by philosophers of chemistry. (shrink)

The first Indian institution for scientific research was founded in 1876. The period 1876–1918 was a time of gestation for Indian chemistry, in which pure research gradually replaced the need-based, result-oriented research formerly promoted by the British regime. This formative period in Indian chemistry came to an end after the First World War and was succeeded by a rapid expansion of chemical research. The educational and political background against which these changes took place, and the influence of European chemistry on (...) developments in India, are discussed. Indian achievements in pure research are summarized, special consideration being given to the work of P. C. Ray, educationalist, entrepreneur, and research chemist. (shrink)

This article provides a theoretical policy-making model of chemical sunset that gradually substitutes green alternatives for persistent toxic substances within a finite timeframe. The technological inflexibility of these substances is a tough obstacle to a chemical sunset, because a chemical sunset seeks to ultimately stop, within a short period of time, the risky businesses of these substances that are highly entrenched into our society. In wrestling with this obstacle, the intelligent precautionary “polluter pays” principle integrates three policy tools: a “precautionary (...) `polluter pays' principle,” “intelligent trial and error,” and democratic “regulatory negotiation.” It is designed to promote technological pluralism and strong democracy, as well as to create either trust or mutual adjustment among relevant groups. (shrink)

In this paper, I explore a seldom-recognized connection between the ontology of abstract objects and a current issue in the philosophy of chemistry. Specifically, I argue that realism with regard to universals implies a view of chemical elements similar to F.A. Paneth’s thesis about the dual nature of the concept of element.

Since the introduction and widespread adoption of chemical herbicides, “weed management” has become almost synonymous with “herbicide management.” Over-reliance on herbicides and herbicide-resistant crops has given rise to herbicide resistant weeds. Integrated weed management (IWM) identifies three strategies for weed management— biological-cultural, chemical-technological, mechanical-physical—and recommends combining all three to mitigate herbicide resistance. However, adoption of IWM has stalled, and research to understand the adoption of IWM practices has focused on single stakeholder groups, especially farmers. In contrast, decisions about weed management (...) often occur within a social ecosystem where multiple stakeholder groups co-create knowledge and practices. To more holistically investigate perceptions and decision-making related to herbicide resistant weed management, we conducted 23 in-depth interviews in combination with Q methodology with farmers and public-/private-sector agricultural professionals in the state of Georgia (U.S.). Our investigation focused on the management of an increasingly herbicide resistant weed, Palmer amaranth, which enabled broader conversations about agricultural systems, farmer livelihoods, and sustainability. Factor and thematic analyses allowed us to identify and characterize two distinct typologies: one primarily valued agronomic efficiency and relied upon chemical-technological management practices, while the other valued diversifying weed management strategies as the pathway to agronomic and economic success. Typologies diverged substantially in attitudes toward the three weed management strategies, the role of technology, and systems management generally. These two viewpoints have implications for how we understand underlying stakeholder motivations and choices around weed management strategies, both of which are crucial in promoting and supporting farmer use of diverse, ecologically-sound, weed management strategies. (shrink)

The concept of living has changed in time along the history of biology and its specificity has been associated or to a particular matter, active such as the chemical one, or was considered as a product of the spatial organization of a passive matter. Today, these two paths can be merged in the chemical perspective that takes account of the general reflections on the complexity and on the systemic, in the “systemic complexity” approach.

Some philosophers have claimed that kinds can be construed as mereologically complex structural properties. This essay examines several strategies aimed at construing a certain class of natural kinds, namely isomeric chemical kinds, in accordance with this view. In particular, the essay examines views which posit structural proper parts in addition to micro-constitutive parts to individuate isomeric chemical kinds. It then goes on to argue that the phenomenon of chirality in stereochemistry gives the proponent of kinds-as-complex-properties evidence for positing the existence (...) of causal-cum-dispositional individuating proper parts, in addition to structural parts, for chemical enantiomeric kinds. (shrink)

The paper surveys the origins of chemical engineering in England in the late nineteenth and early twentieth centuries. It deals particularly with the recognition of the field as an independent discipline, its relations with chemistry and mechanical engineering, and the influence on its growth of industrial ‘demand’. The position of chemical engineering in public discourse, in the City and Guilds Central Institution, and at Imperial College of Science and Technology and University College London are discussed, together with the creation of (...) the Institution of Chemical Engineers in 1922. The idea that the discipline grew merely in response to the demands of industrial capitalists is rejected, and a variety of other interest groups is shown to have participated. (shrink)

Jacques Monod (1971) argued that certain molecular processes rely critically on the property of chemical arbitrariness, which he claimed allows those processes to “transcend the laws of chemistry”. It seems natural, as some philosophers have done, to interpret this in modal terms: a biological relationship is chemically arbitrary if it is possible, within the constraints of chemical “law”, for that relationship to have been otherwise than it is. But while modality is certainly important for understanding chemical arbitrariness, understanding its biological (...) role also requires an account of the concrete causal-functional features that distinguish arbitrary from non-arbitrary phenomena. In this paper I elaborate on this under-emphasised aspect by offering a general account of these features: arbitrary relations are instantiated by mechanisms that involve molecular adapters, which causally couple two properties or processes which would otherwise be uncorrelated. Additionally, adapters work by acting as intermediate rather than cooperating causes. (shrink)

This chapter contains sections titled: Toxic Chemicals in the Arctic Stratospheric Ozone Loss and Global Warming References and Further Reading.

From Mendeleev’s time on, the Periodic Table has been an attempt to exhaust all the chemical possibilities of the elements and their interactions, whether these elements are known as actual or are not known yet as such. These latter elements are called “eka-elements” and there are still some of them in the current state of the Table. There is no guarantee that they will be eventually discovered, synthesized, or isolated as actual. As long as the actual existence of eka-elements is (...) predicted, they cannot be considered as actual but only as purely possible. Given that eka-elements are chemical pure possibilities, a possibilist approach, entitled “panenmentalism,” can gain support as well as an important implication. (shrink)

We argue for an account of chemical reactivities as chancy propensities, in accordance with the ‘complex nexus of chance’ defended by one of us in the past (Suárez, 2017, 2020). Reactivities are typically quantified as proportions, and an expression such as “A + B → C” does not entail that under the right conditions some amounts of A and B react to give the amount of C that theoretically would correspond to the stoichiometry of the reaction. Instead, what is produced (...) is a fraction α < 1 of this theoretical amount, and the corresponding percentage is usually known as the yield, which expresses the relative preponderance of its reaction. This is then routinely tested in a laboratory against the observed actual yields for the different reactions. Thus, on our account, reactivities ambiguously refer to three quantities at once. They first refer to the underlying propensities effectively acting in the reaction mechanisms, and which in ‘chemical chemistry’ (Schummer, 1998) are commonly represented by means of Lewis structures. Besides, reactivities represent the probabilities that these propensities give rise to, for any amount of the reactants to combine as prescribed. This last notion is hence best understood as a single case chance and corresponds to a theoretical stoichiometric yield. Finally, reactivities represent the actual yields observed in experimental runs, which account for and provide the requisite evidence for / against both the mechanisms and single case chances ascribed. (shrink)

Medical expertise plays a major role in large-scale welfare arrangements, for example, in private insurance companies. It symbolizes the objectivity and reliability of the procedures of risk selection and legitimates the acceptance and rejection of clients. To understand "reliability" in this context, this article discusses the introduction of chemical urine analysis for life insurance examination between 1880 and 1920. The article argues that reliability of urine analysis is not an intrinsic characteristic of the technology and thus cannot serve as the (...) explanation for the relevance of this technology as a means of risk selection. The construction of a "reliable technology" went hand in hand with the development of a standardized, uniform, and predictable performance of the test and an emergence of specific network—namely, a large-scale, bureaucratic insurance practice in which examination rooms of physicians became connected to the head offices of insurance companies by administrative means. During this process, the balance of power between medical examiners and insurance companies was reversed. Insurance compa nies depended on medicine for risk selection, but physicians increasingly had to act according to the rules set by life insurance companies. (shrink)

Language is an important part of the human culture. It serves for the expression and communication of thoughts. In is article, the problem of chemical jargon as a tool for communication between scientists is discussed.

SummaryThe convening of the first three Solvay Chemistry Conferences in Brussels from 1922–1928 marked an important turning point for the discipline of chemistry. Whereas much of nineteenth-century chemical endeavour had focused on compositional and functional analysis of chemical compounds, many leaders in chemistry were turning to questions of molecular dynamics by the early twentieth century. Two competing schools of chemical dynamics, which were represented at the Solvay Conferences, were a predominantly English group (Lowry, Lapworth, Robinson, Ingold) who worked out electron (...) and ionic interpretations of organic reaction mechanisms, and a French group (Perrin, Job) who developed a generalized radiation hypothesis of reaction activation. While differences in conceptual and stylistic approach separated the two schools, they agreed on the need to apply contemporary physical theory to old chemical problems, and to develop a theoretical chemistry complementary to theoretical physics. (shrink)

Quine, taking the molecular constitution of matter as a paradigmatic example, offers an account of the relation between theory confirmation and ontology. Elsewhere, he deploys a similar ontological methodology to argue for the existence of mathematical objects. Penelope Maddy considers the atomic/molecular theory in more historical detail. She argues that the actual ontological practices of science display a positivistic demand for “direct observation,” and that fulfillment of this demand allows us to distinguish molecules and other physical objects from mathematical abstracta. (...) However, the confirmation of the atomic/molecular theory and the development of scientists’ ontological attitudes towards atoms was more complicated and subtle than even Maddy supposes. The present paper argues that the history of the theory in fact supports neither Quine’s and Maddy’s accounts of scientific ontology. There was no general demand from scientists to “see” atoms before they were reckoned to be real; but neither did the indispensable appearance of atoms in the best theory of chemical combination suffice to convince scientists of their reality. (shrink)

Unlike other branches of science, the scientific products of synthetic chemistry are not only ideas but also new substances that change our material world, for the benefit or harm of living beings. This paper provides for the first time a systematical analysis of moral issues arising from chemical synthesis, based on concepts of responsibility and general morality. Topics include the questioning of moral neutrality of chemical synthesis as an end in itself, chemical weapons research, moral objections against improving material conditions (...) of life by chemical means, and freedom of research. The paper aims at providing both a sound basis for moral judgements of chemistry in a public discourse and a framework for chemists to reflect on the moral relevance of their activity. (shrink)

The past thirty years have seen substantive debate on the nature of Robert Boyle’s self-described “Mechanical” or “Corpuscularian” philosophy, its treatment of kinds and qualities, its relation to his experimental studies, its relation to other sixteenth- and seventeenth-century matter theories, and its role in the development of chemistry. Using several different strands from this literature, Marina Banchetti-Robino aims to show how Boyle addresses issues relevant to philosophy of chemistry today: the emergent nature of chemical properties, the mereology of fundamental chemical (...) wholes, and the nonreducibility of chemistry to physics. The last issue frames the whole book, which she describes... (shrink)

The belief in the Darwinian theory of evolution appeared to be shaken when one tried to interpret statements of molecular biology in it. As a consequence there arose a theory of non-Darwinian neutral evolution. The supporters of this theory believe that under natural conditions no factors exist which can distinguish and select organisms on their internal (molecular) structure. In the opinion of these neutralists natural selection cannot in principle control the molecular constitution of organisms. Contrary to the viewpoint of the (...) critics of neutralism it is impossible to admit that nucleic acids, proteins and other biomolecules can evolve without the participation of natural selection. This controversy in contemporary theoretical biology can be solved by integrating the conceptions of molecular ecology with Darwinian theory. Molecular ecology acknowledges the interactions of organisms by means of chemical substances synthesized by them. Such chemical ecological factors play a leading part in the selective stages of biomolecular evolution. These diverse chemical ecological interrelations take place intensively when living beings interact with parasitic microbes. (shrink)

The debate between ontological reductionists and emergentists in chemistry has revolved around quantum mechanics. What Franklin and Seifert (BJPS 2020) add to the long-running dispute is an attention to the measurement problem. They contend that all three realist interpretations of the quantum formalism capable of resolving the measurement problem also obviate any need for chemical emergence. I push their argument further, arguing that the realist interpretations of quantum mechanics actually subvert the basis for reduction as well, by undercutting the idea (...) that fundamental physical particles are actual parts of molecules. With both reduction and traditional synchronic emergence pictures ruled out, the only option for realists about quantum chemistry is strong Thomistic emergence. (shrink)

Crutchfield and Redinger (2024) argue that, ceteris paribus, it is morally worse to deploy a restraint that undermines a basic liberty than one that does not.1 This is a plausible view, and is like...

The chemical characterization of the substance responsible for the phenomenon of “transformation” of pneumococci was presented in the now famous 1944 paper by Avery, MacLeod, and McCarty. Reception of this work was mixed. Although interpreting their results as evidence that deoxyribonucleic acid (DNA) is the molecule responsible for genetic changes was, at the time, controversial, this paper has been retrospectively celebrated as providing such evidence. The mixed and changing assessment of the evidence presented in the paper was due to the (...) work’s interpretive flexibility – the evidence was interpreted in various ways, and such interpretations were justified given the neophytic state of molecular biology and methodological limitations of Avery’s transformation studies. I argue that the changing context in which the evidence presented by Avery’s group was interpreted partly explains the vicissitudes of the assessments of the evidence. Two less compelling explanations of the reception are a myth-making account and an appeal to the wartime historical context of its publication. (shrink)