Correspondence testing to research discrimination in the marketplace has become common and the use of internet applications has allowed researchers to send greater numbers of applications. While qu...

Panel data from the German SOEP is used to test for risk vulnerability in the wider population. Two different survey responses are analysed: the response to the question about willingness-to-take risk in general and the chosen investment in a hypothetical lottery. A convenient indicator of background risk is the VDAX index, an established measure of volatility in the German stock market. This is used as an explanatory variable in conjunction with HDAX, the stock market index, which proxies wealth. The impacts (...) of these measures on risk attitude are identifiable by exploiting the time dimension of the panel and matching survey months with corresponding observations from these time-varying factors. Both of the survey responses allow us to test for decreasing absolute risk aversion ; in one case, we find strong evidence of DARA, while in the other, we do not. Both survey responses also allow us to test for RV, and in both cases we find strong evidence. In the case of the hypothetical lottery response, we are also able to estimate a “coefficient of risk vulnerability”. This is defined as the absolute amount by which absolute risk aversion rises in response to a doubling of background risk. We estimate CRV to be between 1.03 and 1.27. (shrink)

This article examines the problem of the origins of the correspondence principle formulated by Bohr in 1920 and intends to test the correctness of the argument that the essential elements of that principle were already present in the 1913 “trilogy”. In contrast to this point of view, moreover widely shared in the literature, this article argues that it is possible to find a connection between the formulation of the correspondence principle and the assessment that led Bohr to abandon (...) the search for a Planck-type theory. In fact, a thorough examination of Bohr’s works shows that the birth of this principle coincided with the depletion of a research program whose origins may date back to Bohr’s stay at the Rutherford’s laboratory (summer 1912). Finally, this article argues that original program of research was abandoned when it became clear that Planck’s quantum hypothesis for the harmonic oscillator was not an adequate support for the theoretical architecture of atomic physics; namely, there was evidence enough to justify a most drastic conclusion, according to Bohr: “I do not think that a theory of the Planck type can be made logical consistent”. (shrink)

The CP-violation problem and unconditional tests of discrete symmetries T and CPT are investigated in the exact quantum theory (QT) beyond the usually used Lee-Oehme-Yang (LOY) theory, which is based on the famous Weisskopf-Wigner (WW) approximation. New unconditional CP-violation effects, independent from those known before, new unconditional tests of the CPT and T invariances, and new results for correlations are derived. Corresponding general results are obtained for\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document} $$K^0 - \bar K^0,{\mathbf{ }}B^0 (...) - \bar B^0,{\mathbf{ }}D^0 - \bar D^0 $$ \end{document} mesons. On the base of these new theoretical results, some proposals for experiments by CP LEAR and ϕ, B factories are given. The new results are interesting not only for the CP-violation problem itself but also for testing violation of the standard quantum dynamics connected with ideas of quantum gravity. (shrink)

Schwartz developed his Theory of Basic Human Values and corresponding instruments, the portrait values questionnaire (PVQ) and the Schwartz values survey (SVS), in order to measure personal values. He uses these instruments (in a slightly modified form) in conjunction with his Theory of Cultural Value Orientations to measure cultural or societal values. His theoretical work is also used in studying organizational values; however, none of these instruments seem suitable to compare personal and perceived organizational values. If the PVQ is widely (...) used to measure personal values, and we need commensurate measures of the person and organization for comparative analysis, then can we not minimally adjust the PVQ to measure organizational values? In this article we discuss the testing of one such adjusted PVQ used for gauging universities’ organizational values. We developed the PVQ-uni to measure university values as perceived by students. We collected data from sociology departments at two universities, one in Austria ( n = 133) and one Nigeria ( n = 156). We then tested the reliability and the validity of the new instrument. Based on the data collected, we found that the PVQ-uni is a reliable and valid instrument; however, further refinements are needed for the instrument to be used successfully in Africa. (shrink)

The traditional role which correspondence rules, coordinating definitions, or semantical rules, have in a logical analysis of a scientific theory is questioned by providing an alternative analysis. The alternative account suggests that scientific theories are "meaningful" prior to the establishment of correspondence rules, and that correspondence rules are introduced to permit explanation and testing in the "observational" sector. The role of models is briefly assessed in connection with this prior or "antecedent theoretical meaning," and a causal (...) sequence analysis of a class of correspondence rules is presented which makes explicit the interdependence of scientific theories. (shrink)

-/- For all that digital methods—including network visualization, text analysis, and others—have begun to show extensive promise in philosophical contexts, a tension remains between two uses of those tools that have often been taken to be incompatible, or at least to engage in a kind of trade-off: the discovery of new hypotheses and the testing of already-formulated positions. This paper presents this basic distinction, then explores ways to resolve this tension with the help of two interdisciplinary case studies, taken (...) from preregistration in contemporary science and the debate over whig history in the history of science. These case studies, the paper argues, refocus our attention from a mutually exclusive testing/discovery binary to the relationship between our background data or philosophical views and the empirical generalizations that we might draw from the data. Finally, it develops a set of three challenges for philosophers and corresponding avenues for future work that will, it is hoped, allow us to better justify our use of these methods. (shrink)

Correspondences and similarities between ideas in shamanism and ideas in contemporary cognitive science are considered. The importance of interconnectedness in the web of life worldview characteristic of shamanism and in connectionist models of semantic memory in cognitive science, and the extension of meaning to elements of the natural world in shamanism and indistributed cognition, are considered. Cognitive consequences of such an extension (e.g., use of representativeness and intentional stance heuristics, magical thinking, social attribution errors, and social in‐group/out‐group differences) are discussed. (...) It is suggested that attributions of mental states, beliefs, and desires to a computer on the basis of behavioral measures (e.g., the Turing test) is consistent with the extension of meaning and intentionality to nonhuman elements of the natural world in shamanism. In general, the existence of such correspondencesand similarities suggests that elements of shamanism may reflect cognitive structures and processes that are also used by nonshamans and in nonshamanic settings. (shrink)

Exploring how people represent natural categories is a key step toward developing a better understanding of how people learn, form memories, and make decisions. Much research on categorization has focused on artificial categories that are created in the laboratory, since studying natural categories defined on high-dimensional stimuli such as images is methodologically challenging. Recent work has produced methods for identifying these representations from observed behavior, such as reverse correlation (RC). We compare RC against an alternative method for inferring the structure (...) of natural categories called Markov chain Monte Carlo with People (MCMCP). Based on an algorithm used in computer science and statistics, MCMCP provides a way to sample from the set of stimuli associated with a natural category. We apply MCMCP and RC to the problem of recovering natural categories that correspond to two kinds of facial affect (happy and sad) from realistic images of faces. Our results show that MCMCP requires fewer trials to obtain a higher quality estimate of people’s mental representations of these two categories. (shrink)

A pure significance test would check the agreement of a statistical model with the observed data even when no alternative model was available. The paper proposes the use of a modified p -value to make such a test. The model will be rejected if something surprising is observed. It is shown that the relation between this measure of surprise and the surprise indices of Weaver and Good is similar to the relationship between a p -value, a corresponding odds-ratio, and a (...) logit or log-odds statistic. The s -value is always larger than the corresponding p -value, and is not uniformly distributed. Difficulties with the whole approach are discussed. (shrink)

The interest in crossmodal correspondences, including those involving sounds and involving tastes, has experienced rapid growth in recent years. However, the mechanisms underlying these correspondences are not well understood. In the present study (N = 302), we used an associative learning paradigm, based on previous literature using simple sounds with no consensual taste associations (i.e., square and triangle wave sounds at 200 Hz) and taste words (i.e., sweet and bitter), to test the influence of two potential mechanisms in establishing sound–taste (...) correspondences and investigate whether either learning mechanism could give rise to new and long‐lasting associations. Specifically, we examined an emotional mediation account (i.e., using sad and happy emoji facial expressions) and a transitive path (i.e., sound‐taste correspondence being mediated by color, using red and black colored squares). The results revealed that the associative learning paradigm mapping the triangle wave tone with a happy emoji facial expression induced a novel crossmodal correspondence between this sound and the word sweet. Importantly, we found that this novel association was still present two months after the experimental learning paradigm. None of the other mappings, emotional or transitive, gave rise to any significant associations between sound and taste. These findings provide evidence that new crossmodal correspondences between sounds and tastes can be created by leveraging the affective connection between both dimensions, helping elucidate the mechanisms underlying these associations. Moreover, these findings reveal that these associations can last for several weeks after the experimental session through which they were induced. (shrink)

Approx. 60–80 million couples globally are affected by the problem of infertility. The issue is important both for the couple trying to conceive and for the whole society in which the couple lives. Lifestyle, including nutrition, may have both a positive and a negative impact on the outcomes of infertility treatment. The aim of this paper is to assess the relationship between knowledge in the area of fertility diet and its actual use, and types of fertility disorders among women undergoing (...) treatment in a fertility clinic. A group of women was analyzed statistically, divided into 3 groups according to their couple’s cause of infertility – the causes of infertility were described as: the male factor, the female factor, and the idiopathic factor. The study group answered questions that comprised a fertility diet knowledge test; the frequency of consumption of particular food products in a individual groups was also analyzed. Correspondence analysis showed differences between the groups in the number of points scored in the fertility diet knowledge test, as well as in the consumption of sweets, crisps and sticks, and nuts and seeds. Women among whom the main cause of infertility was defined as the male factor scored the highest numbers of points in the fertility diet knowledge test, women with the idiopathic cause of infertility scored slightly lower numbers of points, while women whose main cause of infertility was defined as the female factor scored the lowest numbers of points. Women from couples with idiopathic infertility consumed sweets, crisps and sticks the most often, followed by women with the cause of infertility identified on their side, with the lowest frequency of consumption of sweets identified among women whose partner was infertile. Nuts and seeds were consumed the most frequently by women whose partners were infertile, followed by women with the cause of infertility identified on their side, while women with the idiopathic cause of infertility consumed nuts and seeds the least frequently. These examples show that correspondence analysis is well suited to the assessment of the influence of lifestyle on fertility; in addition, it makes it possible to recognize certain correlations that may not be observed in standard statistical tests. (shrink)

This paper proposes a uniform method for constructing tests, confidence regions and point estimates which is called exact since it reduces to Fisher's so-called exact test in the case of the hypothesis of independence in a 2 × 2 contingency table. All the wellknown standard tests based on exact sampling distributions are instances of the exact test in its general form. The likelihood ratio and x2 tests as well as the maximum likelihood estimate appears as asymptotic approximations to the corresponding (...) exact procedures. (shrink)

A model $M$ of countable similarity type and cardinality $\kappa$ is expandable if every consistent extension $T_{1}$ of its complete theory with $|T_{1}|\leq \kappa$ is satisfiable in $M$ and it is compactly expandable if every such extension which additionally is finitely satisfiable in $M$ is satisfiable in $M$ . In the countable case and in the case of a model of cardinality $\geq 2^{\omega}$ of a superstable theory without the finite cover property the notions of saturation, expandability and compactness for (...) expandability agree. The question of the existence of compactly expandable models which are not expandable is open. Here we present a test which serves to prove that a compactly expandable model of cardinality $\geq 2^{\omega}$ of a superstable theory is expandable. It is stated in terms of the existence of a certain elementary submodel whose corresponding theory of pairs of models satisfies a weak elimination of Ramsey quantifiers. (shrink)

The well-known formal semantics of conditionals due to Stalnaker Studies in logical theory, Blackwell, Oxford, 1968), Lewis, and Gärdenfors The logic and 1140 epistemology of scientific change, North-Holland, Amsterdam, 1978, Knowledge in flux, MIT Press, Cambridge, 1988) all fail to distinguish between trivially and nontrivially true indicative conditionals. This problem has been addressed by Rott :345–370, 1986) in terms of a strengthened Ramsey Test. In this paper, we refine Rott’s strengthened Ramsey Test and the corresponding analysis of explanatory relations. We (...) show that our final analysis captures the presumed asymmetry between explanans and explanandum much better than Rott’s original analysis. (shrink)

Since Turing proposed the first test of intelligence, several modifications have been proposed with the aim of making Turing’s proposal more realistic and applicable in the search for artificial intelligence. In the modern context, it turns out that some of these definitions of intelligence and the corresponding tests merely measure computational power. Furthermore, in the framework of the original Turing test, for a system to prove itself to be intelligent, a certain amount of deceit is implicitly required which can have (...) serious security implications for future human societies. In this article, we propose a unified framework for developing intelligence tests which takes care of important ethical and practical issues. Our proposed framework has several important consequences. Firstly, it results in the suggestion that it is not possible to construct a single, context independent, intelligence test. Secondly, any measure of intelligence must have access to the process by which a problem is solved by the system under consideration and not merely the final solution. Finally, it requires an intelligent agent to be evolutionary in nature with the flexibility to explore new algorithms on its own. (shrink)

Symbolic representation acquisition is the complex cognitive process consisting of learning to use a symbol to stand for something else. A variety of non-human animals can engage in symbolic representation learning. One particularly complex form of symbol representation is the associations between orthographic symbols and speech sounds, known as grapheme–phoneme correspondence. To date, there has been little evidence that animals can learn this form of symbolic representation. Here, we evaluated whether an Umbrella cockatoo (Cacatua alba) can learn letter-speech (...) class='Hi'>correspondence using English words. The bird-participant was trained with phonics instruction and then tested on pairs of index cards while the experimenter spoke the word. The words were unknown to the bird and the experimenter was blinded to the correct card position. The cockatoo’s accuracy (M = 71%) was statistically significant. Further, we found a strong correlation between the bird’s word-identification success and the number of overlapping letters between words, where the more overlapping letters between words, the more likely the cockatoo answered incorrectly. Our results strongly suggest that parrots may have the ability to learn grapheme–phoneme correspondences. (shrink)

The process dissociation procedure (PDP) of implicit sequence learning states that the correct inclusion-task response contains the incorrect exclusion-task response. However, there has been no research to test the hypothesis. The current study used a single variable (Stimulus Onset Asynchrony SOA: 850 ms vs. 1350 ms) between-subjects design, with pre-task resting-state fMRI, to test and improve the classical PDP to the mutually exclusive theory (MET). (1) Behavioral data and neuroimaging data demonstrated that the classical PDP has not been validated. In (...) the SOA = 850 ms group, the correct inclusion-task response was at chance, but the incorrect exclusion-task response occurred greater than chance. In the SOA = 850 ms group, the two responses were not correlated, but in the SOA = 1,350 ms group and putting the two groups together, the two responses were in contrast to each other. In each group, brain areas whose amplitude of low frequency fluctuations (ALFFs) in the resting-state related to the two responses were either completely different or opposite to one another. However, the results were perfectly consistent with the MET proposed by the present study which suggests that the correct inclusion-task response is equal to the correct exclusion-task response is equal toC+A1, and the incorrect exclusion-task response is equal toA2.Cdenotes the controlled response andA1andA2denote two different automatic responses. (2) The improved PDP was proposed to categorize the 12 kinds of triplets as delineating four knowledge types, namely non-acquisition of knowledge, uncontrollable knowledge, half-controllable knowledge, and controllable knowledge with the MET. ALFFs in the resting-state could predict the four knowledge types of the improved PDP among two groups. The participants’ control of the four knowledge types (degree of consciousness) gradually improved. Correspondingly, the brain areas in the resting-state positively related to the four knowledge types, gradually changed from the sensory and motor network to the somatic sensorimotor network, and then to the implicit learning network, and then to the consciousness network. The brain areas in the resting-state negatively related to the four knowledge types gradually changed from the consciousness network to the sensory and motor network. As SOA increased, the brain areas associated with almost all the four knowledge types changed. (3) The inhomogeneous hypothesis of the MET is best suited to interpret behavioral and neuroimaging data; it states that the same components among the four knowledge types are not homogeneous, and the same knowledge types are not homogeneous between the two SOA groups. (shrink)

This article describes three experiments that would advance our understanding of the import of data already generated by scientific work on free will and related issues. All three can be conducted with existing technology. The first concerns how reliable a predictor of behavior a certain segment of type I and type II RPs is. The second focuses on the timing of conscious experiences in Libet-style studies. The third concerns the effectiveness of conscious implementation intentions. The discussion of first two experiments (...) highlights some important problems with certain inferences made on the basis of existing data in scientific work on free will. The discussion of the third calls attention to powerful evidence that conscious intentions sometimes are among the causes of corresponding actions. This evidence has been largely ignored in the literature on free will. (shrink)

While epistemic democrats have claimed that majority rule recruits the wisdom of the crowd to identify correct answers to political problems, the conjecture remains abstract. This article illustrates how majority rule leverages the epistemic capacity of the electorate to practically enhance the instrumental value of elections. To do so, we identify a set of sufficient conditions that effect such a majority rule mechanism, even when the decision in question is multidimensional. We then look to the case of sociotropic economic voting (...) in US presidential elections to provide empirical tractability for these conditions. We find that absent such an epistemic capacity a number of presidential elections might well have been decided differently. By generating clear conditions for the plausibility of claims made by epistemic democrats, and demonstrating their correspondence to empirical data, this article strengthens the broader instrumental grounds recommending democracy. (shrink)

The last couple of years have seen a rapid growth of interest in the study of crossmodal correspondences – the tendency for our brains to preferentially associate certain features or dimensions of stimuli across the senses. By now, robust empirical evidence supports the existence of numerous crossmodal correspondences, affecting people’s performance across a wide range of psychological tasks – in everything from the redundant target effect paradigm through to studies of the Implicit Association Test, and from speeded discrimination/classification tasks through (...) to unspeeded spatial localisation and temporal order judgment tasks. However, one question that has yet to receive a satisfactory answer is whether crossmodal correspondences automatically affect people’s performance , as opposed to reflecting more of a strategic, or top-down, phenomenon. Here, we review the latest research on the topic of crossmodal correspondences to have addressed this issue. We argue that answering the question will require researchers to be more precise in terms of defining what exactly automaticity entails. Furthermore, one’s answer to the automaticity question may also hinge on the answer to a second question: Namely, whether crossmodal correspondences are all ‘of a kind’, or whether instead there may be several different kinds of crossmodal mapping . Different answers to the automaticity question may then be revealed depending on the type of correspondence under consideration. We make a number of suggestions for future research that might help to determine just how automatic crossmodal correspondences really are. (shrink)

This article seeks to provide a historically well-informed analysis of an important post-Newtonian area of research in experimental physics between 1798 and 1898, namely the determination of the mean density of the earth and, by the end of the nineteenth century, the gravitational constant. Traditionally, research on these matters is seen as a case of “puzzle solving.” In this article, the author shows that such focus does not do justice to the evidential significance of eighteenth- and nineteenth-century experimental research on (...) the mean density of the earth and the gravitational constant. As Newton’s theory of universal gravitation was mainly based on astronomical observation, it remained to be shown that Newton’s law of universal gravitation did not break down at terrestrial distances. In this context, Cavendish’ experiment and related nineteenth-century experiments played a decisive role, for they provided converging and increasingly stronger evidence for the universality of Newton’s theory of gravitation. More precisely, the author shall argue that, as the accuracy and precision of the experimental apparatuses and the procedures to eliminate external disturbances involved increasingly improved, the empirical support for the universality of Newton’s theory of gravitation improved correspondingly. (shrink)

Accurately assessing youth mental health involves obtaining reports from multiple informants who typically display low levels of correspondence. This low correspondence may reflect situational specificity. That is, youth vary as to where they display mental health concerns and informants vary as to where and from what perspective they observe youth. Despite the frequent need to understand and interpret these informant discrepancies, no consensus guidelines exist for integrating informants’ reports. The path to building these guidelines starts with identifying factors (...) that reliably predict the level and form of these informant discrepancies, and do so for theoretically and empirically relevant reasons. Yet, despite the knowledge of situational specificity, few approaches to integrating multi-informant data are well-equipped to account for these factors in measurement, and those that claim to be well-positioned to do so have undergone little empirical scrutiny. One promising approach was developed roughly 20 years ago by Kraemer and colleagues. Their Satellite Model leverages principal components analysis and strategic selection of informants to instantiate situational specificity in measurement, namely components reflecting variance attributable to the context in which informants observe behavior, the perspective from which they observe behavior, and behavior that manifests across contexts and perspectives. The current study represents the first construct validation test of the Satellite Model. A mixed-clinical/community sample of 134 adolescents and their parents completed six parallel surveys of adolescent mental health. Adolescents also participated in a series of simulated social interactions with research personnel trained to act as same-age, unfamiliar peers. A third informant viewed these interactions and completed the same surveys as parents and adolescents. We applied the Satellite Model to each set of surveys and observed high internal consistency estimates for each of the six-item trait, context, and perspective components. Scores reflecting the trait, context, and perspective components displayed distinct patterns of relations to a battery of criterion variables that varied in the context, perspective, and source of measurement. The Satellite Model instantiates situational specificity in measurement and facilitates unifying conceptual and measurement models of youth mental health. (shrink)

Multiple versions of the Chinese Remote Associates Test have been developed. Thus far, all CRATs have employed verbal stimuli; other forms of stimuli have not yet been used. In this context, the present study compiled a Chinese Visual Remote Associates Test that conforms to the Chinese language and culture based on a picture naming database. The developed CVRAT has two versions, CVRAT-A and CVRAT-B, each comprising 20 test questions. A typical CVRAT question consists of three stimuli pictures, requiring respondents to (...) propose a target word that is semantically associated with all the pictures. When compiling the CVRAT, this study first selected target words, sifted through stimuli words and corresponding pictures, and analyzed pilot test questions. After compilation, their reliability and validity were examined. The results showed that the CVRAT had moderate internal consistency reliability, good criterion-related validity for the Chinese Word Remote Associates Test, Chinese Radical Remote Associates Test, Chinese Compound Remote Associates Test, insight problem-solving, as well as acceptable discriminant validity for fluency, flexibility, and originality of a divergent thinking test. In other words, CVRAT can effectively measure remote associative capability and provides a figural creativity test that facilitates the understanding of different kinds of remote associations. (shrink)

Koriat & Goldsmith's distinction between the correspondence and storehouse metaphors is valuable for both memory theory and methodology. It is questionable, however, whether this distinction underlies the heated debate about so called “everyday memory” research. The distinction between experimental and naturalistic methodologies better characterizes this debate. I compare these distinctions and discuss how the methodological distinction, between experimental and naturalistic designs, could give rise to different theoretical approaches.

Change seems missing in Hamiltonian General Relativity's observables. The typical definition takes observables to have $0$ Poisson bracket with \emph{each} first-class constraint. Another definition aims to recover Lagrangian-equivalence: observables have $0$ Poisson bracket with the gauge generator $G$, a \emph{tuned sum} of first-class constraints. Empirically equivalent theories have equivalent observables. That platitude provides a test of definitions using de Broglie's massive electromagnetism. The non-gauge ``Proca'' formulation has no first-class constraints, so everything is observable. The gauge ``Stueckelberg'' formulation has first-class constraints, (...) so observables vary with the definition. Which satisfies the platitude? The team definition does; the individual definition does not. Subsequent work using the gravitational analog has shown that observables have not a 0 Poisson bracket, but a Lie derivative for the Poisson bracket with the gauge generator $G$. The same should hold for General Relativity, so observables change locally and correspond to 4-dimensional tensor calculus. Thus requiring equivalent observables for empirically equivalent formulations helps to address the problem of time. (shrink)

In our dealings with animals at least most of us see them as conscious beings. On the other hand the employment of human categories to animals seems to be problematic. Reflecting on the details of human beliefs, for example, casts serious doubt on whether the cat is able to believe anything at all. These theses try to reflect on methodological issues when investigating animal minds. Developing a theory of animal mentality seems to be a test case of the interdisciplinary research (...) programme in cognitive science. From the philosopher`s perspective the most pressing problem is how to talk about animal minds. Can we just employ the vocabulary of human psychology? If not, exploring animal minds contains the non-trivial task of introducing a terminology that allows to see the distinctness of animal minds and to see its connection to the human case. The treatment of some topic in cognitive science has to reach a reflective equilibrium between our intuitions, a phenomenological approach, philosophical conceptual analysis, various empirical approaches and model building. Reflective equilibrium means in this context that we have to reach a coherent model which incorporates as much of our intuitions concerning animal consciousness and integrates at the same time the findings of the different co-operating sciences. There can be various trade-offs in case of conflict between, say, philosophical definitions of mental terms as to be applied to animals, neurophysiology, our reflected intuitions and ethological model building based on a computational theory of animal minds. The paper gives an example of reflective equilibrium in discussing the case for awareness in vertebrates. It considers the role of evolutionary reasoning. The main focus lays on two examples of comparing our human notions with corresponding abilities in animals, and how an appropriate conceptual apparatus dealing with the abilities of animals could be introduced. (shrink)

In this paper we examine the theoretical foundations underlying the testing of quantum electrodynamics. We show that for the photon propagator (together with the contiguous vertices) it is not necessary to introduce ad hoc modifications in sufficiently accurate scattering experiments. Energy, momentum transfer, and accuracy determine the tested length in a model-independent way. The situation is quite different with the electron propagator. If gauge invariance is taken for granted, the electron propagator cannot be tested with processes where diagrams with (...) open electron lines are important in the lowest order of perturbation theory. These processes can only give limits for anomalous moment and multiphoton parts of the vertices. On the other hand, processes with closed electron loops (vacuum polarization), such as photon-photon and Delbrück scattering, as well as photon splitting or corresponding low-energy, high-precision experiments can give limits also for the electron propagator. But in these cases only less accurate limits can be obtained, which depend on the modification model. Hence testing of the electron propagator, i.e., roughly speaking, the Dirac equation, is much more difficult than testing of the photon propagator, i.e, Maxwell's equations. (shrink)

If a doctor is trying to decide whether or not to provide a medical treatment, does it matter ethically whether that treatment has already been started? Health professionals sometimes find it harder to stop a treatment (withdraw) than to refrain from starting the treatment (withhold). But does that feeling correspond to an ethical difference? In this article, we defend equivalence—the view that withholding and withdrawal of treatment are ethically equivalent when all other factors are equal. We argue that preference for (...) withholding over withdrawal could represent a form of cognitive bias—withdrawal aversion. Nevertheless, we consider whether there could be circumstances in which there is a moral difference. We identify four examples of conditional nonequivalence. Finally, we reflect on the moral significance of diverging intuitions and the implications for policy. We propose a set of practical strategies for helping to reduce bias in end-of-life decision making, including the equivalence test. (shrink)

Modern medicine emphasizes treatment of the sick. It is often said that the widespread genetic testing soon to follow the completion of the Human Genome Project will usher in a new era of preventive medicine. Such changes require new ways of thinking, however. For example, there may be nothing clinically wrong with a healthy patient who requests genetic testing, even if the tests reveal disease genes. Since all individuals have genetic skeletons in their closets, it is important to (...) be careful not to confuse having disease genes with having the diseases that they cause. Unfortunately, many in the public have adopted a kind of genetic determinism that sees genes as destiny: for example, having the gene associated with colon cancer means they will develop colon cancer. Physicians tend to be more careful, yet even they are not immune to subtle versions of genetic determinism. One example of this is the uncritical categorization of certain diseases as “genetic”. In fact, an adequate concept of genetic disease is extremely difficult to come by. The simplest notion would require a 1:1 correspondence between a disease and its genes, but this is the exception rather than the rule. For example, cystic fibrosis (CF) is often put forward as a good example of a genetic disease, since it seems to result from mutations in a single gene, CFTR. Even in this case, however, the exact relationship between CFTR mutations and disease is not clear, as virtually every possible combination of sweat chloride test results, genetic test results, and symptoms has been observed.[1] If a patient presents with the classic symptoms of CF and is found to have a mutation in the CFTR gene, the physician might understandably infer that the mutation caused the disease. But if an asymptomatic patient is tested and it is discovered that he or she has a CFTR mutation, it is unclear what this means. The doctor might tell the patient the gene is abnormal and that he or she is likely to develop pulmonary problems, etc., but it’s not really known whether even this qualified prognosis is true.. (shrink)

To model a (particular kind of) physical system, the perspective that encompasses preparations, tests and the interplay between them is crucial. In this paper, we employ the conceptual and technical framework presented by Buffernoir (2023) to model physical systems through this pivotal lens, utilizing Chu spaces. With some intuitive and operational axioms we manage to reproduce the following fundamental and abstract results, as well as (part of) the involved reasoning: (1) the states corresponding to a property form a (bi-orthogonally) closed (...) set; (2) the properties form an orthomodular lattice. Adding some idealistic axioms, we can derive: (1) the pure states form a quantum Kripke frame in the sense of Zhong (2017, 2021, 2023); (2) the properties form an irreducible propositional system in the sense of Piron (1976), isomorphic to the lattice of closed sets of pure states. Our axioms are different from those in Buffernoir (2023): on the one hand, they say less about the structure of mixed states; on the other hand, they are arguably more intuitive and operational. The work formalizes some important reasoning about quantum systems, reveals some implicit idealization behind the Hilbert space formalism of quantum theory and hints at other possible formalisms. Finally, it is argued that the framework can be applied to classical physics at an abstract level as well as naturally extended with probabilities. (shrink)

This paper presents the leading idea of my doctoral dissertation and thus has been shaped by the reactions of all the members of my thesis committee: Charles Chastain, Walter Edelberg, W. Kent Wilson, Dorothy Grover, and Charles Marks. I am especially grateful for the help of Professors Chastain, Edelberg, and Wilson; each worked closely with me at one stage or another in the development of the ideas contained in the present work. Shorter versions of this paper were presented at the (...) 47th Annual Northwest Conference on Philosophy (1995), the 1996 Mid-South Philosophy Conference, the 1997 meeting of the Central Division of the American Philosophical Association, and at the University of Washington, Seattle; thanks to all audiences for their insightful comments and questions and also to my conference commentators, Eric Gampel, Jonathan Cohen, and Bruce Glymour, respectively, each of whom offered a thoughtful critique. Lastly, I extend my gratitude to anonymous referees, including two from Mind and Language, whose remarks led to significant improvements in the paper. Address for correspondence: 13416, 4th Ave. S., Seattle, WA 98168, USA E-mail: robrupert@aol.com.. (shrink)

Using a design-based research approach, we studied ways to advance opportunities for children and families to engage in engineering design practices in an informal educational setting. 213 families with 5–11-year-old children were observed as they visited a tinkering exhibit at a children’s museum during one of three iterations of a program posing an engineering design challenge. Children’s narrative reflections about their experience were recorded immediately after tinkering. Across iterations of the program, changes to the exhibit design and facilitation provided by (...) museum staff corresponded to increased families’ engagement in key engineering practices. In the latter two cycles of the program, families engaged in the most testing, and in turn, redesigning. Further, in the latter cycles, the more children engaged in testing and retesting during tinkering, the more their narratives contained engineering-related content. The results advance understanding and the evidence base for educational practices that can promote engineering learning opportunities for children. (shrink)

Testing the other. It is nowadays a commonplace of academic discourse on social sciences, especially when it comes to such disciplines as anthropology and semiotics, to oppose the old (and old-fashioned) methods of the “structuralists” to post-modern and post-structural epistemological attitudes. Structuralism, it is said, was based on the idea that it is possible to apprehend the meaning of cultural productions from an exterior and therefore objective standpoint, just by making explicit their immanent principles of organization. Today, on the (...) contrary, a totally distinct approach of cultural productions would stem from the consciousness of a strict interdependence, or even of an identity in nature between subject and object at all levels of the process of knowledge, at least in the area of the humanities. However, such a crude opposition proves insufficient when one observes the effective practices of current research. The example here analysed is the account given by the American anthropologist Paul Rabinow of his first mission abroad: Reflections on Fieldwork in Morocco. The analysis, based on the use of a semiotic modelling of interaction, consists in exploring the variety of positions respectively adopted by the anthropologist and his informants according to circumstances and contexts. Four regimes are in principle distinguishable: programmation, based on regularity and predictability of the actors’ behaviour, manipulation, based on some kind of contractualization of their relationships, adjustment, based upon reciprocal sensitivity and various strategies permitting to both partners of the interaction to test one another, and a regime of consent to the unexpected or the unforeseeable. The main result of the analysis resides in the possibility of showing that at each of these styles of pragmatic interaction corresponds a specific regime at the cognitive level as well. This leads tostressing the complexity, if not heterogeneity, of the strategies of knowledge involved at various stages of anthropological research, from the collection ofdata to the cooperative production of new forms of understanding. Taking the risk of generalization, one might also consider the interactional device, which ishere tested through the reading of P. Rabinow’s report as a metatheoretical model describing the various epistemological stances at work and at stake in thepractices of research in social sciences at large. (shrink)

Theories of statistical testing may be seen as attempts to provide systematic means for evaluating scientific conjectures on the basis of incomplete or inaccurate observational data. The Neyman-Pearson Theory of Testing (NPT) has purported to provide an objective means for testing statistical hypotheses corresponding to scientific claims. Despite their widespread use in science, methods of NPT have themselves been accused of failing to be objective; and the purported objectivity of scientific claims based upon NPT has been called (...) into question. The purpose of this paper is first to clarify this question by examining the conceptions of (I) the function served by NPT in science, and (II) the requirements of an objective theory of statistics upon which attacks on NPT's objectivity are based. Our grounds for rejecting these conceptions suggest altered conceptions of (I) and (II) that might avoid such attacks. Second, we propose a reformulation of NPT, denoted by NPT*, based on these altered conceptions, and argue that it provides an objective theory of statistics. The crux of our argument is that by being able to objectively control error frequencies NPT* is able to objectively evaluate what has or has not been learned from the result of a statistical test. (shrink)

Purpose – The purpose of this paper is to explore artificial moral agency by reflecting upon the possibility of a Moral Turing Test and whether its lack of focus on interiority, i.e. its behaviouristic foundation, counts as an obstacle to establishing such a test to judge the performance of an Artificial Moral Agent. Subsequently, to investigate whether an MTT could serve as a useful framework for the understanding, designing and engineering of AMAs, we set out to address fundamental challenges within (...) the field of robot ethics regarding the formal representation of moral theories and standards. Here, typically three design approaches to AMAs are available: top-down theory-driven models and bottom-up approaches which set out to model moral behaviour by means of models for adaptive learning, such as neural networks, and finally, hybrid models, which involve components from both top-down and bottom-up approaches to the modelling of moral agency. With inspiration from Allen and Wallace as well as Prior, we elaborate on theoretically driven approaches to machine ethics by introducing deontic tense logic. Finally, within this framework, we explore the character of human interaction with a robot which has successfully passed an MTT. Design/methodology/approach – The ideas in this paper reflect preliminary theoretical considerations regarding the possibility of establishing a MTT based on the evaluation of moral behaviour, which focusses on moral reasoning regarding possible actions. The thoughts reflected fall within the field of normative ethics and apply deontic tense logic to discuss the possibilities and limitations of artificial moral agency. Findings – The authors stipulate a formalisation of logic of obligation, time and modality, which may serve as a candidate for implementing a system corresponding to an MTT in a restricted sense. Hence, the authors argue that to establish a present moral obligation, we need to be able to make a description of the actual situation and the relevant general moral rules. Such a description can never be complete, as the combination of exhaustive knowledge about both situations and rules would involve a God eye’s view, enabling one to know all there is to know and take everything relevant into consideration before making a perfect moral decision to act upon. Consequently, due to this frame problem, from an engineering point of view, we can only strive for designing a robot supposed to operate within a restricted domain and within a limited space-time region. Given such a setup, the robot has to be able to perform moral reasoning based on a formal description of the situation and any possible future developments. Although a system of this kind may be useful, it is clearly also limited to a particular context. It seems that it will always be possible to find special cases in which a given system does not pass the MTT. This calls for a new design of moral systems with trust-related components which will make it possible for the system to learn from experience. Originality/value – It is without doubt that in the near future we are going to be faced with advanced social robots with increasing autonomy, and our growing engagement with these robots calls for the exploration of ethical issues and stresses the importance of informing the process of engineering ethical robots. Our contribution can be seen as an early step in this direction. (shrink)

In recent years, neologicists have demonstrated that Hume's principle, based on the one-to-one correspondence relation, suffices to construct the natural numbers. This formal work is shown to be relevant for empirical research on mathematical cognition. I give a hypothetical account of how nonnumerate societies may acquire arithmetical knowledge on the basis of the one-to-one correspondence relation only, whereby the acquisition of number concepts need not rely on enumeration (the stable-order principle). The existing empirical data on the role of (...) the one-to-one correspondence relation for numerical abilities is assessed and additional empirical tests are proposed. In the final part, it is argued that the fact that the successor relation and the one-to-one correspondence relation can play independent roles in number concept acquisition may be a complication for testing the Whorfian hypothesis. (shrink)

Instead of the usual asymptotic passage from quantum mechanics to classical mechanics when a parameter tended to infinity, a sharp boundary is obtained for the domain of existence of classical reality. The last is treated as separable empirical reality following d'Espagnat, described by a mathematical superstructure over quantum dynamics for the universal wave function. Being empirical, this reality is constructed in terms of both fundamental notions and characteristics of observers. It is presupposed that considered observers perceive the world as a (...) system of collective degrees of freedom that are inherently dissipative because of interaction with thermal degrees of freedom. Relevant problems of foundation of statistical physics are considered. A feasible example is given of a macroscopic system not admitting such classical reality.The article contains a concise survey of some relevant domains: quantum and classical Bell-type inequalities; universal wave function; approaches to quantum description of macroscopic world, with emphasis on dissipation; spontaneous reduction models; experimental tests of the universal validity of the quantum theory. (shrink)

The Intelligence Quotient (IQ) tests and the corresponding psychometric explanations dominate both the scientific and popular views about human intelligence. Though the IQ tests have been in currency for long, there exists a gap in what they are believed to measure and what they do. While the IQ tests index the quality of cognitive functioning in selected domains of mental repertoire, the applied settings often inflate their predictive value leading to an interpretive gap. The present article contends that studying the (...) influence of motivational and affective processes on cognitive functioning would help to evolve a more psychologically comprehensive account of the IQ tests and bridge the interpretive gap. To conclude, the article suggests possible future research directions that could strengthen the predictive value of the IQ tests. (shrink)

In a recent study of a patient in a persistent vegetative state, [Owen, A. M., Coleman, M. R., Boly, M., Davis, M. H., Laureys, S., & Pickard, J. D. . Detecting awareness in the vegetative state. Science, 313, 1402] claimed that they had demonstrated the presence of consciousness in this patient. This bold conclusion was based on the isomorphy between brain activity in this patient and a set of conscious control subjects, obtained in various imagery tasks. However, establishing consciousness in (...) unresponsive patients is fraught with methodological and conceptual difficulties. The aim of this paper is to demonstrate that the current debate surrounding consciousness in VS patients has parallels in the artificial intelligence debate as to whether machines can think. Basically, used a method analogous to the Turing test to reveal the presence of consciousness, whereas their adversaries adopted a line of reasoning akin to Searle’s Chinese room argument. Highlighting the correspondence between these two debates can help to clarify the issues surrounding consciousness in non-communicative agents. (shrink)

This paper provides an in-depth analysis and discussion of the key issues of quality management, evaluation, and detection contained in big data for automotive application scenarios. A generalized big data quality management model and programming framework are proposed, and a series of data quality detection and repair interfaces are built to express the processing semantics of various data quality issues. Through this data quality management model and detection and repair interfaces, users can quickly build custom data quality detection and repair (...) tasks for different data quality requirements. To improve the operational efficiency of complex data quality management algorithms in large-scale data scenarios, corresponding parallelization algorithms are studied and implemented for detection and repair algorithms with long computation time, including priority-based multiconditional function-dependent detection and repair algorithms, entity detection, and extraction algorithms based on semantic information and chunking techniques, and plain Bayesian-based missing value filling algorithms, and this paper proposes a data validity evaluation algorithm and enhances the validity of the original data in practical applications by adding temporal weights, and finally it passed the experimental validation. Through the comprehensive detection process of data importance, network busyness, duration of transmission process, and failure situation, the efficiency has been increased by 20%, and an adaptive data integrity detection method based on random algorithm and encryption algorithm is designed. After experimental verification, this method can effectively detect the integrity of the data transmission process and improve the application of data value, and the final effect is increased by 30.5%. (shrink)

Health behaviours of preschool children have a considerable impact on the shaping of habits later on in their lives. Parents’ and guardians’ role is to develop positive health patterns and represent exemplary models to be followed by children. The aim of the paper is to present the use of correspondence analysis for the assessment of the relationship between eating habits of parents and children, as well as for the determination of the most common situations in which preschool children consume (...) fast-food products and to find the relationship between the frequency of fast-food consumption and BMI values in preschool children. The tests were carried out with the use of an own survey carried out in kindergartens in Białystok among parents dropping off and picking up children. 149 correctly filled questionnaires were obtained. The statistical analysis employs the chi-squared test and correspondence analysis. Among the tested children, a statistically significant relationship between body weight and sex was obtained. In the group of children and parents consuming fast-foods, a statistically significant relationship between the frequency of children’s and parents’ consumption of the products in question was noticed. A statistically significant relationship between the age of introduction of fast-food products into the child’s diet and their BMI was found. A situation that was statistically significant as far as contribution to frequent consumption of fast-food products by children, i.e. at least once a week, were children and parents shopping together. The relationship between the frequency of fast-food consumption by parents and children was presented in the form of correspondence maps, as well as the relationship between the child’s BMI and the age when the first fast-food product is served, and the relationship between the child’s BMI and the frequency of their consumption of fast-foods. Unfortunately, despite the high awareness among parents of the harmful effects of fast-food products and the widespread health education programmes, a number of the children in kindergartens were overweight or even obese. For this reason, the quality of the educational programmes in kindergartens, as well as in various media outlets, needs to be improved, with emphasis put on their effectiveness, in order to minimise the problem of the occurrence of overweight and obesity in children. It is also important for parents rearing children to pay special attention not only to their children’s menus, but also to foods consumed in the presence of children. (shrink)

This editorial of the special issue addresses the question of whether/how responses to the Covid-19 pandemic corresponded with authentic CSR. The literature on CSR has tended to endorse a business-centric perspective and its inherent focus on the search for alignments between CSR activities and the economic/financial interests of the firm. The Covid-19 pandemic has put this perspective to the test, pushing many companies to engage in distinctively more genuine and authentic CSR and/or demonstrating the importance of prior CSR engagement in (...) facilitating crisis management. The papers included in the special issue appear to converge on the idea that firms combining evidence of both pre-crisis engagement in CSR and strong CSR performance during the crisis (demonstrated through the deployment of various CSR assets and resources, including certified reporting, social marketing, individual engagement, resilience, legitimacy, trust) have coped better. This provides interested researchers with an opportunity to appreciate the value of CSR during a crisis. (shrink)

The scientific life in mid-seventeenth-century Europe was characterised by numerous academies of sciences and scientific associations whose aim was to propagate the development of the sciences, art and literature. Some have called it “the new Age of Academies all over Europe”. These institutions brought together not only educated professionals but also a large number of amateur scientists. They called for the deliberate abandonment of verbal dispute in favour of visual demonstration/experimentation, and for the creation of paid scientific professionals who would (...) devote their full time to the enterprise. These scientists conducted numerous experiments, the results of which were demonstrated at academic sessions. Franciszek Bieliński became Grand Marshal of the Crown in 1742. During the many years of his public service, he aimed to improve the well-being of Warsaw inhabitants, especially by paving the streets and creating a modern sewerage system. In the light of recent scholarly studies, Franciszek Bieliński is perceived as a figure of very wide horizons, striving to join the Parisian academic scientific discourse in order to transfer knowledge and technology to Poland. Bieliński exchanged letters with the eminent member and three-time president of the Paris Academy of Sciences, Henri Louis Duhamel du Monceau, who among numerous other projects tested new methods of horticulture, agriculture and forestry. The article aims to discuss the scientific research undertaken by Bieliński in regards to technology transfer in the area of agriculture, on the basis of unanalysed documents. Recently found correspondence shows that Grand Marshal Bieliński was involved in experimental research supervised by Duhamel du Monceau, under the aegis of the Paris Academy of Sciences. It pertained to modern agricultural crops and the application of new technologies. The agricultural experiments that Bieliński carried out on his private lands in Otwock over many years focused on improving and increasing agricultural production in accordance with the instructions given by Duhamel du Monceau. An interesting research finding was the detailed description of one of the earliest transfers of advanced technology in the field of agricultural machinery. Reports of the work conducted in Poland, which were sent to Duhamel du Monceau, proved to be so useful and important that the latter mentioned these in the proceedings of the Paris Academy of Sciences. (shrink)

In this paper, we examine possible formalisations of the riskiness condition for hypothesis testing. First, we informally introduce derivability and riskiness as testing conditions together with the corresponding arguments for refutation and confirmation. Then, we distinguish two different senses of confirmation and focus our discussion on one of them with the aid of a historical example. In the remaining sections, we offer a brief overview of the main references to the risky condition in the literature and scrutinise different (...) options for formally capturing riskiness; we show why none of them works. We conclude with some remarks about the relation between derivability and riskiness and claim that riskiness essentially involves a contextual, pragmatic component that eludes a complete formal reconstruction. (shrink)

Data mining technology is an effective knowledge mining and data relationship induction technology based on massive data, which is widely used in data analysis in many fields. In order to improve the utilization effect of students’ performance and meet the teaching needs of modern education, data mining technology can be applied to the existing performance database to mine the data information and treatment. Data mining technology is used to analyse and process the data stored in the student achievement management system, (...) which provides the basis for improving the teaching quality and optimizing the teaching resources. Based on the analysis of the relevant data of large-scale English test results, this paper finds out the relevant rules that affect college English test results, forms the corresponding performance prediction rules, uses data mining technology to more comprehensively analyse the factors that affect students’ performance, establishes a model, and uses data mining tools to mine and analyse students’ English test data. It is of great practical significance to select the model with high accuracy, further optimize the parameters, make good use of the data, and then take targeted measures to guide the teaching reform, help students make more efficient learning plans, and improve and perfect the existing problems in teaching. (shrink)

Failings of a categorical systemFor decades, standardized classification systems have attempted to define psychiatric disorders in our mental health care system, with the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5; American Psychiatric Association (APA), 2013) and International Statistical Classification of Diseases and Related Health Problems 10th revision (ICD-10; World Health Organization, 2010) being internationally best-known. One of the major advantages of the DSM must be that it has seriously diminished the international linguistic confusion regarding psychiatric disorders. Since (...) its introduction, it contributed extensively towards one common international language for defining and conceptualizing psychiatric disorders. Strikingly, within the field of psychological testing a similar step forward seems to have not yet been taken. At present, there exists no international standard for the use of psychological tests that takes the definition of a specific symptom as listed in DSM-5 as its starting point, and reliably and validly measures this symptom. Rather, the majority of tests are measuring constructs consisting of a multitude of symptoms. For example, the Beck’s Depression Inventory (Beck et al., 1996) measures core symptoms of depression summing up to a depression score. Accordingly, we believe it is time for a change. The diagnostics of psychiatric disorders, where disorders are defined as nosological units with a single cause, a single organic substrate, and a single time course, has been problematic for centuries. The field of psychiatry has always been ambivalent about its desire to follow a medical model (Blaney, 2015), but afflicted due to its definitions of pathology. The definition of a psychiatric disorder in DSM-5 offers little room for a clear cut pathogenesis and harsh demarcation of syndromes. This is reflected in the DSM-5, where it states: “A mental disorder is a syndrome characterized by clinically significant disturbance in an individual’s cognition, emotion regulation, or behavior that reflects a dysfunction in the psychological, biological, or developmental processes underlying mental functioning” (APA, 2013, p.20). An unfortunate and recognized consequence of this definition within the current system is that many symptoms overlap within categories of psychiatric disorders and patients end up diagnosed with many co-morbid disorders.Two fundamental problemsRegardless of new attempts to improve the diagnostics of psychiatric disorders, the DSM-5 represents the status quo. Consequently, the distinction between diagnosis and classification remains substantial and more than a discussion on semantics. We identify two fundamental problems within the current framework. Generally, a psychiatric diagnosis is considered to be descriptive (Hengeveld and Schudel, 2003). The clinician will describe a syndrome (its nature, timespan, and severity) within the framework of a disorder, and often include a differential diagnosis, predisposing protective or vulnerability factors, and provoking or maintaining factors. Within the DSM-5 framework, a similar ‘approach to clinical case formulation’ is taken (APA, 2013, p. 19). Evidently, a descriptive diagnosis has a hypothetical character. It consists of the clinician’s hypothesis and is based on his or hers professional considerations according to the abovementioned factors. Once the clinician has formulated a descriptive diagnosis, it is then complementary ‘translated’ into a DSM-5 classification. Herein lies the problem. For the layman, the existence of this distinction between diagnosis and classification is usually unknown. Preceding treatment, the clinician will give the client a classification of the existing psychiatric problems and the client may attribute more meaning to it than appropriate, thereby fostering the risk of reification. Second, the DSM-5 is a categorical system. Thus, individual disorders are regarded as discrete units – ‘you either have it, or you don’t’. DSM-5 states about this: “(…) scientific evidence places many, if not most, disorders on a spectrum with closely related disorders that have shared symptoms, shared genetic and environmental risk factors (…)”. And “(…) we have come to recognize that the boundaries between disorders are more porous than originally perceived.” (APA, 2013, p. 6). This leads to a fundamental problem. Because the overwhelming majority of psychiatric disorders examined thus far using taxometric methods appear to be dimensional in nature (Haslam, 2003; Widiger and Samuel, 2005), consequently all of their categorizations become artificial and debatable. Even though DSM-5 took a modest step towards a more dimensional approach, its core remains categorical. To illustrate, consider the Borderline Personality Disorder (BPD). This classification consists of nine diagnostic criteria of which a minimum of five need to be present for the diagnosis of BPD. A simple numerical combination algorithm leads to a staggering number of 256 distinct presentations of BPD (Albion et al., 2013). Due to this chameleon-like nature, the disorder’s diagnostic validity becomes questionable. Strikingly, this number is relatively small when compared to other conditions, e.g., there are 636,120 ways to have posttraumatic stress disorder (Galatzer-Levy and Bryant, 2013).DSM-5 does propose an alternative model for personality disorders based on personality functioning and traits (APA, 2013, p. 761), as a possible answer to the problem that most patients fit with multiple co-morbid personality disorders or to the category of personality disorder not otherwise specified. In November 2012, the chair committee of APA decided to move this alternative model to section III of DSM-5 and to sustain the categorical system in section II. A potential solutionDSM-5 and its predecessors have brought about an invaluable improvement regarding the formulation of a common international language for psychiatric disorders. However, the individual disorders fit poorly with its starting point of discrete units and strict boundaries. Van Os (2014) has argued for a better balance between the categorical and personalized aspects of psychiatric disorders. We argue for a two-step approach.Particularly due to the ‘weak boundaries’ between disorders, it might be beneficial to limit ourselves by merely categorizing clients into the main categories of the DSM-5 according to their most prominent symptoms (Van Os, 2014), i.e. their main complaint. In other words, clinicians could first ask themselves whether the symptomatology is concerning a neurodevelopmental disorder, or a bipolar and related disorder, or a depressive disorder, and so on. It will drastically reduce the over 400 classifications in DSM-5 down to 20 categories. Van Os (2014) even argues to combine some of the main categories, reducing this number even further to 15 categories. The advantages of reducing the over 400 classifications are fivefold: 1) a syndrome, being an aggregation of symptoms, creates a false relation between symptoms that are that are already heterogeneous themselves; 2) 15 broad categories are functional: it results into a very heterogeneous group of clients within a category and thus prevents stereotypes and invites further personalizing of complaints; and 3) a dimensional measure of a symptom rather than a syndrome will correspond better with the client regardless of it not providing the complete picture. Focusing on the main complaint will indicate where there is an immediate need for care (Van Os, 2014); 4) it will allow clinicians to recognise subthreshold conditions more easily (Magruder and Calderone, 2000); and 5) it might facilitate the development of clear demarcations between normal and abnormal functioning (Kessler, 2002; Widiger and Samuel, 2005). Please, see also Table 1.This also fits well within scientific advances, as thus far strongest evidence has been found for a distinction between internalizing and externalizing disorders, even superseding these 15 main categories (DSM-5; APA, 2013, p.13, but see Weiss et al., 1998). The second step would concern the personalized aspect, which we argue to define on a level of core symptoms of the specific main category, to be agreed upon later. To assess these core symptoms, the field of psychological testing could develop an internationally applicable instrument to reliably and validly measure each (core) symptom on a dimensional scale. Many of these instruments are readily available and have proven its psychometric properties within scientific research. Elements from these instruments could be easily transformed to work within the new system. Within the field of psychology, this approach could aid development of a common international language to define symptoms, analogous to the field of psychiatry. Importantly, current psychological testing mainly implies the use of self-report measures. This leads to an abundance of auto-amnestic information. To increase the reliability and validity of psychological tests to assess DSM-5 symptoms, it may be important to add two additional information resources. This would entail psychological tests where a next of kin answers questions about the symptom of the client, and psychological tests that include the clinicians’ judgment, such as structured clinician-based interviews. Conversely, we also need to acknowledge the well-known limitations of clinical judgment (e.g., Faust, 1986; Garb, 1998). Advantages of a new frameworkThe changes we suggest have big implications and are not easily implemented in the current framework. Clients may prefer the comfort of a single clear label, similar to what they are used to in other areas of medicine. Health insurance providers and policy makers may argue for single labels as well. Therefore, it would require a lot of explanation from our clinicians to promote a change. Our suggestions for broader categories may not disambiguate the current situation better than the existing approach, but it will promote personalisation of health care. Difficulties in diagnostic reliability will remain in disorders that fall on the boundaries of the taxons, e.g., schizoaffective disorder versus bipolar disorder with psychotic characteristics, which may benefit from further study. There are also some politically tinged questions to keep in mind: How will we finance our health care, and how will we ensure a gradual transition from the current financing system, including clients who already have their labels? What about visitations from insurers and health inspection? How can they control for a good standard of quality in health care when considering the increasing heterogeneity? Nevertheless, we argue that the benefits outweigh the disadvantages. We will see a shift from a categorical to a personalized approach, which will lead to less (self) stigmatizing, less estrangement, and it will challenge reification thinking. DSM-V states that “a reformulation of research goals should also keep DSM-5 central to the development of dimensional approaches to diagnosis that will likely supplement or supersede current categorical approaches to diagnosis in coming years” (APA, 2013, p. 13). Our proposition for psychological testing on symptom level could contribute to this development. Furthermore, this new approach will do more justice to the heterogeneity of symptoms within and outside of classification categories, see also Table 1. Moreover, in this new approach we join forces of expert knowledge from the fields of psychiatry and psychological science. Finally, it offers new and potentially better opportunities to map health care needs. This in turn will lead to a better interface for allocation of appropriate treatment. It will present a clearer picture of when preventative care is preferred over treatment and vice versa. Importantly, health care needs will be more closely attuned to the ‘own story’ of the client.We argue for the national and international psychological associations in Europe and the United States of America to support the idea of a collective approach to develop an internationally standardized psychological testing battery to reliably assess all the core symptoms of the main categories in DSM-5. (shrink)

This dissertation explores the ethics of human subjects research with particular attention to how clinical research on vaccines differs from research on therapies. The major differences are rooted in the fact that the benefits of vaccines and vaccine research accrue to the community to which vaccines belong by inducing herd immunity and thereby protecting both vaccinated and unvaccinated individuals. Therapeutics have no corresponding benefit to the community, the primary beneficiary is the individual. The ethical justification for conducting vaccine research in (...) a given community therefore should include an evaluation of the risks and benefits to the community as well as to involved individuals. Respect for individuals extends to respect for communities and for individuals as members of communities. A three way partnership between investigators, the community, and the community members is suggested as an ethical foundation for vaccine research. ;This model is then applied to the particular and complex case of testing a preventive HIV vaccine. HIV is an unique virus which continues to cause extraordinary devastation worldwide. The characteristics of HIV, its transmission and epidemiology, along with unprecedented scientific possibilities present a formidable challenge to the development and testing of an HIV vaccine. Using the community model, specific suggestions are made for the ethical conduct of clinical efficacy trials of HIV preventive vaccines. (shrink)