I present—in an extremely sketchy form—a model of two-level, open, plastic and multidimensional human nature. Due to the included attribute of multidimensionality this model opposes the reductive conceptions of man dominating in today’s philosophy. The main objective of the paper is the ontological status of man, especially the ontic foundation of multidimensional man. I demonstrate that this status remains a riddle; one only knows that from the ontological perspective man is a wholly exceptional object, not explainable by to-date ontological (...) constructions. -/- . (shrink)

One of the most important recent developments in the study of concepts has been the resurgence of interest in nativist accounts of the human conceptual system. However, many theorists suppose that a key feature of neural organization—the brain’s plasticity—undermines the nativist approach to concept acquisition. We argue that, on the contrary, not only does the brain’s plasticity fail to undermine concept nativism, but a detailed examination of the neurological evidence actually provides powerful support for concept nativism.

Catherine Malabou's concept of plasticity has influenced and inspired scholars from across disciplines. The contributors to _Plastic Materialities_—whose fields include political philosophy, critical legal studies, social theory, literature, and philosophy—use Malabou's innovative combination of post-structuralism and neuroscience to evaluate the political implications of her work. They address, among other things, subjectivity, science, war, the malleability of sexuality, neoliberalism and economic theory, indigenous and racial politics, and the relationship between the human and non-human. _Plastic Materialities_ also includes three (...) essays by Malabou and an interview with her, all of which bring her work into conversation with issues of sovereignty, justice, and social order for the first time. Contributors. Brenna Bhandar, Silvana Carotenuto, Jonathan Goldberg-Hiller, Jairus Victor Grove, Catherine Kellogg, Catherine Malabou, Renisa Mawani, Fred Moten, Alain Pottage, Michael J. Shapiro, Alberto Toscano. (shrink)

Analysing Jonathan Glazer’s Under the Skin (2013), this article provides an overview of the importation of suture theory from psychoanalysis into film theory and Žižek’s revisiting of this theory, then bringing about a rapprochement between the concepts of suture and Malabou’s destructive plasticity, as expounded in her work The New Wounded. The forms of wounded subjectivity we find there are unable to stitch themselves into the illusory narratives needed to enable them to access a fixed sense of individual or (...) shared identity and enclose them in a subjectivity separated off from all else around. Here, on the contrary, alterity, the alien, is situated within. It is such a form of subjectivity, I argue, that we find in Glazer’s Under the Skin where this narrative plays out not only diegetically, as we witness the alien that has sutured itself inside a human envelope attempt and fail to articulate itself to an external narrative that remains inaccessible to it, but infratextually also. Indeed, ultimately this article suggests that Under the Skin can be read as a commentary on the viewing subject required by (and forms of subjectivity produced by) post-cinematic media forms that at first seem to operate according to a different logic to the cinematic syntax of classical cinema, but which may in fact require us to reconsider some of our assumptions with regard to all forms of cinematic subjectivity produced in the relations between spectator and screen. (shrink)

In this paper, I present an emerging explanatory framework about ageing and care. In particular, I focus on how, in contrast to most classical accounts of ageing, biomedicine today construes the ageing process as a modifiable trajectory. This framing turns ageing from a stage of inexorable decline into the focus of preventive strategies, harnessing the functional plasticity of the ageing organism. I illustrate this shift by focusing on studies of the demographic dynamics in human population, observations of ageing (...) as an intraspecifically heterogenous phenotype, and the experimental manipulation of longevity, in both model organisms and humans. I suggest that such an explanatory framework about ageing creates the epistemological conditions for the rise of a peculiar form of prevention that does not aim to address a specific condition. Rather it seeks to stall the age-related accumulation of molecular damage and functional deficits, boosting individual resilience against age-related decline. I call this preventive paradigm “ground-state prevention.” While new, ground-state prevention bears conceptual resemblance to forms of medical wisdom prominent in classic Galenic medicine, as well as in the Renaissance period. (shrink)

The growing field of evo-devo is increasingly demonstrating the complexity of steps involved in genetic, intracellular regulatory, and extracellular environmental control of the development of phenotypes. A key result of such work is an account for the remarkable plasticity of organismal form in many species based on relatively minor changes in regulation of highly conserved genes and genetic processes. Accounting for behavioral plasticity is of similar potential interest but has received far less attention. Of particular interest is (...) class='Hi'>plasticity in communication systems, where human language represents an ultimate target for research. The present paper considers plasticity of language capabilities in a comparative framework, focusing attention on examples of a remarkable fact: Whereas there exist design features of mature human language that have never been observed to occur in non-humans in the wild, many of these features can be developed to notable extents when non-humans are enculturated through human training. These examples of enculturated developmental plasticity across extremely diverse taxa suggest, consistent with the evo-devo theme of highly conserved processes in evolution, that human language is founded in part on cognitive capabilities that are indeed ancient and that even modern humans show self-organized emergence of many language capabilities in the context of rich enculturation, built on the special social/ecological history of the hominin line. Human culture can thus be seen as a regulatory system encouraging language development in the context of a cognitive background with many highly conserved features. (shrink)

Contrary to assumptions that changes in brain networks are possible only during crucial periods of development, research in the past decade has supported the idea of a permanently plastic brain. Novel experience, altered afferent input due to environmental changes and learning new skills are now recognized as modulators of brain function and underlying neuroanatomic circuitry. Given findings in experiments with animals and the recent discovery of increases in gray and white matter in the adult human brain as a result (...) of learning, the old concept of cognitive reserve, that is the ability to reinforce brain volume in crucial areas and thus provide a greater threshold for age-dependent deficits, has been reinforced. The challenge we face is to unravel the exact nature of the dynamic structural alterations and, ultimately, to be able to use this knowledge for disease management. Understanding normative changes in brain structure that occur as a result of environmental changes and demands is pivotal to understanding the characteristic ability of the brain to adapt. (shrink)

This essay defends the view that, as embodied, our identities are necessarily dependent on the aesthetic environment. Toward this end, it examines the renewal of the concept of sensation (aisthesis) in phenomenology, but then concludes that the methodology and metaphysics of phenomenology must be abandoned in favor of an ontology that sees corporeal identity as generated by the materiality of aesthetic relations. It is suggested that such an ontology is available in the work of Spinoza, which helps break down the (...) natural/ artificial and human/nonhuman distinctions, and can thereby engender an environmental ethics grounded in aesthetic relations. An explication of body/ world dependence is provided via the concept of plasticity and a properly Spinozist aesthetics is invoked, but remains to be worked out. (shrink)

Philosophy & Social Criticism, Volume 48, Issue 8, Page 1140-1173, October 2022. This article explores the complexities of Marcuse’s philosophical anthropology in light of Foucault’s criticisms of Marcuse and the Frankfurt School. While Marcuse’s theory of human nature is grounded upon a dialectical conception of essential human potentialities striving for realization, it secretes a radically plastic conception of life that undermines all anthropological essentialism. This fundamental tension between essentialist and plastic conceptions of human nature has significant implications (...) for rethinking Marcuse’s project and legacy. (shrink)

Agriculture is a serious contributor to pollution and other environmental harms, making it an important site of action for the development of environmentally friendly products and practices. However, farmer adoption of such options is varied and dependent on a wide range of factors including the visual appeal of sustainable farming. Recent studies have shown that negative aesthetics related to more environmentally friendly ways of farming can delay or prevent adoption of such practices. Drawing on the concepts of good farming, cultural (...) capital, and the aesthetics of waste, this paper aims to assess the status of biodegradable plastic mulch in relation to a range of alternative and conventional specialty crop growers’ aesthetic perceptions. BDM has the potential to significantly reduce non-biodegradable polyethylene mulch waste, thus addressing serious environmental and human health concerns. However, the aesthetics of BDM may present a challenge. BDM looks identical to PE plastic, and its degradation throughout the season results in scraps in the soil. To investigate aesthetics as a possible barrier to BDM adoption, we conducted five photo-elicitation focus groups with specialty crop growers in Washington State. Results indicate that alternative growers are slightly more adverse to the aesthetics of BDM, especially because of its ‘plastic’ appearance. Conventional growers had higher rates of BDM adoption, even though they felt a strong aesthetic aversion to the messy nature of BDM degradation. Confidence in the product, particularly as a result of education and experience, was believed to be the key to overcoming this negative aesthetic. Study participants offered a variety of ways to enhance the acceptability of BDM, such as making the mulch brown instead of black. These findings have wider implications for the acceptance and adoption of practices that, although environmentally friendly, have an unattractive visual element. (shrink)

The Continuous Parameter Estimation Model is applied to develop individual genomic-level heritabilities for the latent hierarchical structure and developmental dynamics of Life History (LH) strategy LH strategies relate to the allocations of bioenergetic resources into different domains of fitness. LH has moderate to high population-level heritability in humans, both at the level of the high-order Super-K Factor and the lower-order factors, the K-Factor, Covitality Factor, and General Factor of Personality (GFP). Several important questions remain unexplored. We developed measures of genome-level (...) heritabilities employing an American sample of 316 monozygotic (MZ) and 274 dizygotic (DZ) twin dyads and a Swedish sample of 863 MZ and 475 DZ twin dyads. This novel heritability index measures individual genetic transmissibility, therefore opening new avenues for analyzing complex interactions among heritable traits inaccessible to standard structural equations methods. For these samples: (1) moderate to high heritability of factor loadings of Super-K on its lower-order factors is demonstrated, evidencing biological preparedness, genetic accommodation, and the gene-culture coevolution of biased epigenetic rules of development; (2) moderate to high heritability of the magnitudes of the effect of the higher-order factors upon their loadings on their constituent factors, evidencing genetic constraints upon phenotypic plasticity; and (3) that heritability of the LH factors, of factor loadings, and of the magnitudes of the correlations among factors are weaker among those with slower LH speeds, demonstrating that inter-individual variation in transmissibility is a function of individual socioecological selection pressures. (shrink)

After proposing the Turing Test, Alan Turing himself considered a number of objections to the idea that a machine might eventually pass it. One of the objections discussed by Turing was that no machine will ever pass the Turing Test because no machine will ever “have as much diversity of behaviour as a man”. He responded as follows: the “criticism that a machine cannot have much diversity of behaviour is just a way of saying that it cannot have much storage (...) capacity”. I shall argue that the objection cannot be dismissed so easily. The diversity exhibited by human behaviour is characterized by a kind of context-sensitive adaptive plasticity. Most of the time, human beings flexibly and fluently respond to what is relevant in a given situation. Moreover, ordinary human life involves an open-ended flow of shifting contexts to which our behaviour typically adapts in real time. For a machine to “have as much diversity of behaviour as a man” would be for that machine to keep its responses and behaviour relevant within such a flow. Merely giving a machine the capacity to store a huge amount of information and an enormous number of behaviour-generating rules will not achieve this goal. By drawing on arguments presented originally by Descartes, and by making contact with the frame problem in artificial intelligence, I shall argue that the distinctive context-sensitive adaptive plasticity of human behaviour explains why the Turing Test is such a stringent test for the presence of thought, and why it is much harder to pass than Turing himself may have realized. (shrink)

Does the writing and reading of fiction affect long-term human social behavior? The question of how imaginative literature has impacted human nature is rather difficult to answer given, of course, the minute period of evolutionary time involved. One way it has been done is by linking creative text to oral storytelling, thereby reverse engineering the function of fiction back to its Pleistocene origins. The adaptive advantages probably conferred by storytelling, as Denis Dutton so eloquently showed, include “low-cost and (...) low-risk surrogate experience,” as we explore the “what if” possibilities that might affect our chances of survival; acquiring factual information through rich and striking images; and advancing .. (shrink)

Many researchers consider language to be definitionally unique to humans. However, increasing evidence suggests that language emerged via a series of adaptations to neural systems supporting earlier capacities for visuomotor integration and manual action. This paper reviews comparative neuroscience evidence for the evolutionary progression of these adaptations. An outstanding question is how to mechanistically explain the emergence of new capacities from pre-existing circuitry. One possibility is that human brains may have undergone selection for greater plasticity, reducing the extent (...) to which brain organization is hard-wired and increasing the extent to which it is shaped by socially transmitted, learned behaviors. Mutations that made these new abilities easier or faster to learn would have undergone positive selection, and over time, the neural changes once associated with individual neural plasticity would tend to become heritable, innate, and fixed. Clearly, though, language is not entirely “innate;” it does not emerge without the requisite environmental input and experience. Thus, a mechanistic explanation for the evolution of language must address the inherent trade-off between the evolutionary pressure for underlying neural systems to be flexible and sensitive to environmental input vs. the tendency over time for continually adaptive behaviors to become reliably expressed in an early-emerging, canalized, less flexible manner. (shrink)

Neural transplantation as a recovery strategy for neuro-degenerative diseases in humans has used mainly grafting following acute denervation strategies in young adult hosts. Our work in aged mice and rats demonstrates an age-related increase in susceptibility to oxidative damage from neurotoxins, a remarkably poor recovery of C57BL/6 mice from MPTP insult with transplantation and growth factors, even at 12 months of age, and diminished plasticity of host neurons. We believe that extrapolation of data from young adult animal models to (...) aged humans without thorough investigation of transplantation and host response in aged recipients is scientifically and ethically inappropriate. (shrink)

Purpose. The article is devoted to the analysis of corporality as an attribute of plastic art in the Ancient art, the Middle Ages, the Renaissance, the modernism and the postmodernism. Theoretical basis. The authors consider historical development of the art as a change of paradigms. Within each paradigm a special understanding of art is created, which is characterized both by the act of creativity itself and by the evaluation of its results. Particularly urgent is the task to identify the origins (...) of these changes, to indicate their stages, the direction of the evolution of artistic creativity. In this context, corporality as a paradigm of European plastic art is considered in the article in the concrete historical dimension from the classics to the postmodernism. Originality. Postmodern experiments stimulate blurring the borders between the traditional forms and genres of art. Review of canonical ideas about the creation and destruction, order and chaos in art illustrates conscious reorientation from the classical understanding of artistic creativity to the construction of artifacts-simulacra, which is a characteristic feature in the oeuvre of contemporary artists, ranging from the pop art to the present day. Conclusions. The ideas of postmodern philosophers found their visual embodiment in modern artistic practices. Reconstruction of the body, re-switching of its elements according to the principle of chaotic collage, the interpretation of the human body as a separate substance isolated from the individual him/herself, which is presented as a phenomenon of mass culture, became the basis of the creative method of contemporary plastic art. The ideas of postmodern philosophers have found their visual embodiment in the contemporary artistic practices. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Plastic Turn by Ghosh, RanjanMaria MargaroniGhosh, Ranjan. The Plastic Turn. Cornell University Press, 2022. 224pp.In Plasticity at the Dusk of Writing: Dialectic, Destruction, Deconstruction (2005; 2010), Catherine Malabou argues that “the concept of plasticity is becoming both the dominant formal motif of interpretation and the most productive exegetical and heuristic tool of our time,” supplanting older theoretical paradigms such as “writing” and “the trace” (57). (...) Almost twenty years later, the truth of this statement is certainly confirmed not only by Malabou’s own developing elaboration of this concept and the growing body of works inspired by her creative adaptation of neurological theory in the realm of philosophy, but also by the proliferation of studies that seek to reflect on the ecological, anthropological, ethical, or political consequences of what has been termed the “Plasticene.”1 There is no doubt, then, that we are witnessing yet another “turn” in the Humanities and Social Sciences, the plastic turn coming to displace or supplement a host of currently competing theoretical tendencies: i.e., the material turn, the affective turn, the cognitive turn, and the mimetic turn, among others.2Ranjan Ghosh’s The Plastic Turn is the first in a trilogy intended to theorize the aims, scope and effects of a “plastic Humanities.”3 Interestingly, Ghosh does not locate the “turn” in the 1990s when plastic “gained widespread public acceptance” (Mah 31) and when (with the development of the neurosciences) brain plasticity was increasingly adopted as “the most effective sensor of energy and meaning” of our contemporary era (Malabou, Plasticity 31-32). Instead, he goes back to the turn of the twentieth century when plastic as a new material and plasticity as a scheme of thought were still in the realm of potentiality, triggering, countering, and reshaping many of our political, cultural, and aesthetic modern imaginaries.Much has been written about the promise of plastic as a “magical” substance, capable of sublimating matter into what Roland Barthes describes as the trace of a metamorphic movement that produces an abundance of forms out of the singularity of its origin (104-105). In “The Material Consciousness of Plastics,” Russell Gagg notes that “in the early part of the twentieth century, plastics were seen as leading a new utopian vision for economic growth after the depression of the pre-war and austerity of the post-war years” (32). In the interwar period, plastics were [End Page 149] promoted for their democratic, egalitarian potential in making “designed consumer goods […] commercially viable,” thus introducing an aesthetics of the popular and the banal (Gagg 44-45; Ghosh 9, 20). One of the many strengths of Ghosh’s book is that it takes inspiration not merely from plastic as the stuff of fantasy but also from the very materiality of plastic, namely, its polymeric structure, malleability of form, sensitivity to the change of temperature, crystalline-amorphous texture, diverse modes of esterification, and resistance to biodegradability. In his first chapter, Ghosh acknowledges the influence of Goethe’s Elective Affinities and Primo Levi’s The Periodic Table which, as he argues, bring “the chemical metaphor to bear on human relationships” (20). He points to the development of a body of contemporary works that elaborate a “chemo-poetics,” aiming to “connect life and its undulations with molecular formations” (21).4 In subsequent chapters, the author succeeds in re-molding the chemical metaphor exploited in these works into a full-blown “material-aesthetic” that enables him to produce new readings of the forces behind literary modernism; the possibilities, limits, and stakes of world literature; the emergence of uncanny forms of plastic nature and art; and the distinct affective modalities caused by our petro-modernity.In analyzing side-by-side the diverse histories of, on the one hand, plastic as an increasingly disgraced material and, on the other hand, our literary, aesthetic, and critical production from the early 20th century to the present, Ghosh is dependent on an analogical process that permits him to think across multiple disciplines and subjects, connecting terms, ideas, and practices that resonate but remain asymmetrical (1). As he emphasizes, it is the “asymmetrically analogous (metaphors)” that “deepens the framework of my arguments” (3). Indeed... (shrink)

This essay argues that the reigning medical and scientific understanding of the endocrine system, which insists on its fundamental biological plasticity, was historically constructed through a dual child–animal metaphor. The work accomplished by such organic metaphors, as Donna Haraway terms them, returns us to the endocrine laboratories and clinics in which they were built in Europe and the United States in the first half of the twentieth century. The child and animal metaphors implanted the concept of plasticity into (...) the human body to the effect of bringing sexed and gendered life under the jurisdiction of science and medicine, where it could not only be normalized in a sense long appreciated by transgender studies but also cultivated towards the ostensible “improvement” and “perfection” of the human. This is also, then, a history of the eugenic heritage of modern endocrinology, which has been largely ignored in recent discussions of plasticity and the body’s materiality. To interrogate the role of foundational organic metaphors in endocrinology is to open up plasticity not only to its historical context but also to radical contestation, making the contemporary assumptions of transgender medicine untimely, particularly the medicalization of the transgender child. (shrink)

This chapter analyzes the notion of human nature and the concept of inner nature from the perspective of developmental systems theory. It explores the folkbiology of human nature and looks at three features associated with traits that are expressions of the inner nature that organisms inherit from their parents: fixity, typicality, teleology.

A former student and collaborator of Jacques Derrida, Catherine Malabou has generated worldwide acclaim for her progressive rethinking of postmodern, Derridean critique. Building on her notion of plasticity, a term she originally borrowed from Hegel's _Phenomenology of Spirit_ and adapted to a reading of Hegel's own work, Malabou transforms our understanding of the political and the religious, revealing the malleable nature of these concepts and their openness to positive reinvention. In French to describe something as plastic is to recognize (...) both its flexibility and its explosiveness-its capacity not only to receive and give form but to annihilate it as well. After defining plasticity in terms of its active embodiments, Malabou applies the notion to the work of Hegel, Heidegger, Levinas, Levi-Strauss, Freud, and Derrida, recasting their writing as a process of change between dialectic and deconstruction. Malabou contrasts plasticity against the graphic element of Derrida's work and the notion of trace in Derrida and Levinas, arguing that plasticity refers to sculptural forms that accommodate or express a trace. She then expands this analysis to the realms of politics and religion, claiming, against Derrida, that "the event" of justice and democracy is not fixed but susceptible to human action. (shrink)

In this review, we focus on the evolutionary and biomedical aspects of the architecture of human chromosome 3 (HSA3) by analyzing chromosomal regions that have been conserved during the evolutionary process, compared to those that have been involved in the genomic restructuring of different placental lineages. Given that the organization of human chromosome 3 is derived when compared to the ancestral primate karyotype, and is an autosome that is commonly implicated in human tumour formation, we examined the (...) patterns of change and the genomic consequences that have resulted from its complex evolutionary history. The data show four discrete chromosomal regions that are frequently implicated in chromosomal rearrangements (3p25, 3p22, 3p12 and 3q21). These are rich in repetitive elements and are commonly implicated in structural rearrangements that underpin human genomic disorders and neoplasias. Additional Supporting Information may be found in the online version of this article. BioEssays 30:1126–1137, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

Donald J. Munro's essay, "When Science Is in Defense of Value-Linked Facts," takes a stand against the fact-value dichotomy which has been heavily pronounced within the Greco-European philosophical canon. As Munro also points out, the continuing persistence of the fact-value dichotomy is traceable to Moore's discussion of the "naturalistic fallacy" and Hume's discussion of the is-ought problem. In opposition to these two views, classical Confucian thinkers present us with descriptive statements about human commonalities, including their inborn affects....

Name der Zeitschrift: Neue Zeitschrift für Systematische Theologie und Religionsphilosophie Jahrgang: 59 Heft: 1 Seiten: 34-53.

Theories are processes modelled by thought. When they evolve in time, they are transformed and become new theories. They may cross from one academic discipline to another, then open up to new areas of human knowledge, mixing together the humanities, art, science and even spirituality. The way they are modelled reveals their plasticity and their elasticity is tested in their potential for transfer from one field to another, while the different contacts they make and mergers they undergo generate (...) a certain hybridity. Plasticity, elasticity and hybridity are the triad which makes the transfer of theories possible. (shrink)

Recent advances in cognitive science and cognitive neuroscience open up new vistas for human enhancement. Central to much of this work is the idea of new human-machine interfaces (in general) and new brain-machine interfaces (in particular). But despite the increasing prominence of such ideas, the very idea of such an interface remains surprisingly under-explored. In particular, the notion of human enhancement suggests an image of the embodied and reasoning agent as literally extended or augmented, rather than the (...) more conservative image of a standard (non-enhanced) agent using a tool via some new interface. In this essay, I explore this difference, and attempt to lay out some of the conditions under which the more radical reading (positing brand new integrated agents or systemic wholes) becomes justified. I adduce some empirical evidence suggesting that the radical result is well within our scientific reach. The main reason why this is so has less to do with the advancement of our science (though that certainly helps) than with our native biological plasticity. We humans, I shall try to show, are biologically disposed towards literal (and repeated) episodes of sensory re-calibration, of bodily re-configuration and of mental extension. Such potential for literal and repeated re-configuration is the mark of what I shall call "profoundly embodied agency," contrasting it with a variety of weaker (less philosophically and scientifically interesting) understandings of the nature and importance of embodiment for minds and persons. The article ends by relating the image of profound embodiment to some questions (and fears) concerning converging technologies for improving human performance. (shrink)

I identify six types of phenotypic plasticity and categorize them with respect to their cognitive status. I look at differences and relations between some of these types of plasticity and then analyze how phenotypic outcomes are transmitted across generations. I engage with the relevant literature on developmental scaffolding and entrenchment in cultural evolution. I argue that that the typology I present here can be beneficial for such a debate and therefore instructive to better comprehend the evolution and development (...) of human cognition. (shrink)

Recent developments in cognitive science provide compelling leads that need to be interpreted and synthesized within the context of semiotic and biosemiotic principles. To this end, we examine the impact of the mind-body unity on the sorts of choices that an organism is predisposed to making from its Umwelt. In multicellular organisms with brains, the relationship that an organism has with its Umwelt impacts on neural plasticity, the functional specialisations that develop within the brain, and its behaviour. Clinical observations, (...) such as those recorded by Norman Doidge, as well as historical observations from outside the field of semiotics (Plato, Aristotle, Hume) shed further light on this process, and serve to further substantiate our semiotic and biosemiotic paradigm. Our analysis develops a rather limited associationism (with reference to Peirce’s categories) into a more general and robust interpretation that is applicable to all mind-bodies, whether they be neurons, paramecia and amoebae, or humans, cats and dogs. Biosemiotics is a more universal semiotics that takes us beyond the confines of anthropocentrism, because it recognizes the role of the body in shaping Mind. (shrink)

Radically new or unexpected findings in a science demand an openness to new concepts and styles of explanation. The time is more than ripe for asking ourselves what we have learned from the research program of comparative genomics. Where not long ago the human genome was expected to reveal a close association of complexity with the quantitative expansion of the roster of unique genes, more recent findings, especially in relation to comparisons between human and chimp, have raised the (...) bracing possibility that when it comes to complexity, it may be that `less is more'. But `less is more' is not the only observation or inference that follows from the data. The idea of `progressive detachment' will be introduced and set forth as the most perspicuous conceptual resource for unifying and interpreting the overall findings from comparative genomics to date. (shrink)

Single-sided deafness (SSD) or profound unilateral hearing loss obligates the only serviceable ear to capture all acoustic information. This loss of binaural function taxes cognitive resources for accurate listening performance, especially under adverse environments or challenging tasks. We hypothesized that adults with SSD would manifest both functional and structural brain plasticity compared to controls with normal binaural hearing. We evaluated functional alterations using magnetoencephalographic imaging (MEGI) of brain activation during performance of a moderately difficult auditory syllable sequence reproduction task (...) and assessed structural integrity using diffusion tensor magnetic resonance imaging (DTI). MEGI showed the SSD cohort to have increased induced oscillations in the theta band over the left superior temporal cortex and decreased induced gamma band oscillations over the frontal and parietal cortices between 175-475 ms following stimulus onset. DTI showed the SSD cohort to have extensive fractional anisotropy reduction in both auditory and non-auditory tracts and regions. Overlaying functional and structural changes revealed by the two imaging techniques demonstrated close registration of cortical areas and white matter tracts that expressed brain plasticity. Hence, complete loss of input from one ear in adulthood triggers both functional and structural alterations to dorsal temporal and frontal-parietal areas. (shrink)

Western science claims to provide unique, objective information about the world. This is supported by the observation that peoples across cultures will agree upon a common description of the physical world. Further, the use of scientific instruments and mathematics is claimed to enable the objectification of science. In this work, carried out by reviewing the scientific literature, the above claims are disputed systematically by evaluating the definition of physical reality and the scientific method, showing that empiricism relies ultimately upon the (...) human senses for the evaluation of scientific theories and that measuring instruments cannot replace the human sensory system. Nativist and constructivist theories of human sensory development are reviewed, and it is shown that nativist claims of core conceptual knowledge cannot be supported by the findings in the literature, which shows that perception does not simply arise from a process of maturation. Instead, sensory function requires a long process of learning through interactions with the environment. To more rigorously define physical reality and systematically evaluate the stability of perception, and thus the basis of empiricism, the development of the method of dimension analysis is reviewed. It is shown that this methodology, relied upon for the mathematical analysis of physical quantities, is itself based upon empiricism, and that all of physical reality can be described in terms of the three fundamental dimensions of mass, length and time. Hereafter the sensory modalities that inform us about these three dimensions are systematically evaluated. The following careful analysis of neuronal plasticity in these modalities shows that all the relevant senses acquire from the environment the capacity to apprehend physical reality. It is concluded that physical reality is acquired rather than given innately, and leads to the position that science cannot provide unique results. Rather, those it can provide are sufficient for a particular environmental setting. (shrink)

Experience-dependent neural plasticity is high in the developing brain, presenting a unique window of opportunity for training. To optimize existing training programs and develop new interventions, it is important to understand what processes take place in the developing brain during training. Here, we systematically review MRI-based evidence of training-induced neural plasticity in children and adolescents. A total of 71 articles were included in the review. Significant changes in brain activation, structure, microstructure, and structural and functional connectivity were reported (...) with different types of trainings in the majority of the studies. Significant correlation of performance improvement with neural changes was reported in 51% of the studies. Yet, only 48% of the studies had a control condition. Overall, the review supports the hypothesized neural changes with training while at the same time charting empirical and methodological desiderata for future research. (shrink)

There is a hoary tradition in moral philosophy that assumes we cannot determine which moral theory is acceptable or correct unless we have available a correct theory of human nature, or, in its more modern form, of the person. With such a theory of the person, however, we could at least narrow down the choice among competing ethical theories. A more recent tradition, at least in one of its standard interpretations, agrees it would be necessary to have a correct (...) theory of the person before we could determine an acceptable moral theory, but it denies there is a determinate nature of the person to be captured in such a theory. The plasticity of the person, according to this strand of Marxist theory, rules out the possibility of there being universal moral theory at all. In this paper, I would like to explore a view that treads an intermediate path. It agrees with the Marxist denial that there is a determinate nature of the person, a deep fact of the matter, that can be abstracted from the social matrix and made the subject of a theory of the person. And, it agrees with both traditions that moral theory depends on and embodies a theory of the person. But, by making the problem of arriving at an acceptable view of the person itself something that depends on overall theoretical considerations, including moral ones, the intermediary, view may be able to avoid the type of moral relativism associated with the Marxist view. (shrink)

The paper aims at proposing an extended notion of epigenesis acknowledging an actual causal import to the phenotypic dimension for the evolutionary diversification of life forms. “Introductory remarks” section offers introductory remarks on the issue of epigenesis contrasting it with ancient and modern preformationist views. In “Transmutation of forms: phenotypic variation, diversification, and complexification” section we propose to intend epigenesis as a process of phenotypic formation and diversification dependent on environmental influences, independent of changes in the genomic nucleotide sequence, and (...) occurring during the whole life span. Then, “Evolvability and phenotypic evolution” section focuses on phenotypic plasticity and offers an overview of basic properties that allows biological systems to be evolvable—i.e. to have the potentiality of producing phenotypic variation. Successively, the emphasis is put on environmentally-induced modifications in the regulation of gene expression giving rise to phenotypic variation and diversification. After some brief considerations on the debated issue of epigenetic inheritance, the issue of culture is considered. The key point is that, in the case of humans and of the evolutionary history of the genus Homo at least, the environment is also, importantly, the cultural environment. Thus, “Bio-cultural feedback” section argues that a bio-cultural feedback should be acknowledged in the “epigenic” processes leading to phenotypic diversification and innovation in Homo evolution. Finally, “Brain plasticity and cultural neural reuse” section introduces the notion of “cultural neural reuse”, which refers to phenotypic/neural modifications induced by specific features of the cultural environment that are effective in human cultural evolution without involving genetic changes. Therefore, cultural neural reuse may be regarded as a key instance of the bio-cultural feedback and ultimately of the extended notion of epigenesis proposed in this work. (shrink)

This article provides an ethnographic account of pediatric cochlear implantation, revealing an important shift in the definition of deafness from a sensory loss to a neurological processing problem. In clinical and long-term therapeutic practices involved in pediatric implantation, the cochlear implant is recast as a device that merely provides access to the brain. The “real” treatment emerges as long-term therapeutic endeavors focused on neurological training. This redefinition then ushers in an ensuing responsibility to “train the brain,” subsequently displacing failure from (...) the device onto the individual’s ability to train his or her brain. New caregiving techniques that accompany implantation are understood through neuropolitics, showing how parents are encouraged to engage in neuro-self-governance, and how the concept of neuroplasticity is used to cultural ends. (shrink)

This article locates a theoretical reflection on the form of legal subjectivity against twenty-first century complexities and pressures, including the structural complexities visible in biotechnological developments, new hybridities and numerous contemporary theoretical and practical manifestations of heterogeneity, multiplicity and complexity emerging in a range of disciplines, including cybernetics, techno-theory, post-humanism and ecology. The author defends the theoretical and critical utility of understanding the legal subject as an explicit (and explicitly limited ) constructus . Criticising the constructed naturalism (and the historical (...) and contemporary exclusions) of the 'human being' of law, the author suggests that the language and concept of the 'legal entity' (rather than that of the 'legal person') draws attention to the patterned 'gap' between law and life (and to related injustices enacted by the form of the materialisation of legal subjectivity) while simultaneously providing the degree of theoretical plasticity now required by the mutable complexities of the twenty-first century and beyond. (shrink)

Plasticity of body representation fundamentally underpins human tool use. Recent studies have demonstrated remarkably complex plasticity of body representation in humans, showing that such plasticity (1) occurs flexibly across multiple time scales and (2) involves multiple body representations responding differently to tool use. Such findings reveal remarkable sophistication of body plasticity in humans, suggesting that Vaesen may overestimate the similarity of such mechanisms in humans and non-human primates.

The aim of this paper is to argue against the claim that the term “belief”, as it functions in philosophical psychology, has natural-kind term semantics; this thesis is central to the famous Lycan–Stich argument against eliminative materialism. I will argue that the current debate concerning the discrepancy between the professed opinions and actions, especially the debate concerning the idea of aliefs, shows that the concept of belief is plastic and amenable to conceptual engineering. The plasticity and amenability to conceptual (...) engineering of the concept of belief give us, in turn, a reason to doubt that “belief” functions in a way that is presupposed in the Lycan–Stich argument. Finally, I point to an alternative to both eliminativism and the natural kind view, namely the idea that we should treat belief as a human kind. (shrink)

A theoretical divide exists on the study of the adapted psychological mechanisms underlying human culture. It has been said for instance that we evolved a brain for all seasons and that this is opposed to the framework of the modularity of mind. We approach the nature of these explanatory differences based on what we judge to be a misunderstanding with respect to the evolution of domain-specific modules. We underline the fact that the input-domain of a module and its ecological (...) function should not be conflated. We propose a more generous way of considering how evolutionary functions in mental architecture account for the possibility of general adaptations for cultural cognition. We show that modularity happens to be a good tool to research and decompose mechanisms with plastic functions such as in some forms of social learning. The idea of "modules for all seasons" is so vindicated. Existe una divisoria teórica en el estudio de los mecanismos psicológicos biológicamente adaptados que subyacen a la cultura humana. Se ha dicho, por un lado, que hemos evolucionado un cerebro para todas las estaciones, lo que se opone, por el otro, al marco de la modularidad de la mente. Consideramos la naturaleza de estas diferencias explicativas sobre la base de lo que nos parece un error de comprensión acerca de la evolución de módulos específicos de dominio. Subrayamos el hecho de que el dominio de entrada de un módulo y su función ecológica no deben ser confundidos. Proponemos una manera más generosa de considerar cómo las funciones evolutivas de la arquitectura mental pueden dar cuenta de la posibilidad de adaptaciones generales a la cognición cultural. Mostramos que la modularidad resulta ser un buen instrumento para investigar y descomponer mecanismos con funciones plásticas, como las que encontramos en algunas formas de aprendizaje social. De este modo, se defiende la idea de "módulos para todas las estaciones". (shrink)

Adapting Minds: Evolutionary Psychology and the Persistent Quest for Human Nature DAVID BULLER Cambridge, MA: MIT Press, 2005 564 pages, ISBN: 0262025795 (hbk); $37.00.

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